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https://www.readbyqxmd.com/read/29233408/structured-academic-discussions-through-an-online-education-specific-platform-to-improve-pharm-d-students-learning-outcomes
#1
Srikanth Kolluru, James T Varughese
OBJECTIVE: To facilitate active academic discussions using an online, education-centered platform and reinforce concepts, in order to improve overall course outcomes. MATERIALS AND METHODS: A third year integrated pharmacotherapy course was enrolled on an online searchable platform, Piazza®, to facilitate academic discussions. Students could ask, answer, and explore content, and build on submitted answers in wiki style in collaboration. Instructor posted learning objectives, endorsed student responses with correct answers and led follow-up discussions...
March 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29233302/validation-of-a-motivation-survey-tool-for-pharmacy-students-exploring-a-link-to-professional-identity-development
#2
Martina F Mylrea, Tarun Sen Gupta, Beverley D Glass
INTRODUCTION: Self-determination theory (SDT), which describes a continuum of motivation regulators, is proposed as an appropriate framework to study pharmacy student motivation. The aim was to develop a Pharmacy Motivation Scale (Pharm-S) to determine motivation regulators in undergraduate students and explore a possible link to professional identity development. METHODS: The Pharm-S was adapted from the SDT-based, Sports Motivation Scale (SMS-II), and administered to undergraduate students in an Australian pharmacy course...
September 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29222046/erratum-to-ultrasound-mediated-nanoparticle-delivery-across-ex-vivo-bovine-retina-after-intravitreal-injection-eur-j-pharm-biopharm-119-2017-125-136
#3
Di Huang, Ying-Shan Chen, Sachin S Thakur, Ilva D Rupenthal
No abstract text is available yet for this article.
December 5, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29200459/competency-programming-and-emerging-innovation-in-graduate-education-within-schools-of-pharmacy-the-report-of-the-2016-2017-research-and-graduate-affairs-committee
#4
Samuel M Poloyac, Kirsten F Block, Jane E Cavanaugh, Linda P Dwoskin, Russell B Melchert, Ruth E Nemire, James M O'Donnell, Ronny Priefer, Daniel R Touchette
Graduate education in the pharmaceutical sciences is a cornerstone of research within pharmacy schools. Pharmaceutical scientists are critical contributors to addressing the challenges of new drug discovery, delivery, and optimal care in order to ensure improved therapeutic outcomes in populations of patients. The American Association of Colleges of Pharmacy (AACP) charged the 2016-2017 Research and Graduate Affairs Committee (RGAC) to define the competencies necessary for graduate education in the pharmaceutical sciences (Charge 1), recommend collaborative curricular development across schools of pharmacy (Charge 2), recommend AACP programing for graduate education (Charge 3), and provide guidance on emerging areas for innovation in graduate education (Charge 4)...
October 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/29195125/effects-of-continuation-electroconvulsive-therapy-on-quality-of-life-in-elderly-depressed-patients-a-randomized-clinical-trial
#5
W Vaughn McCall, Sarah H Lisanby, Peter B Rosenquist, Mary Dooley, Mustafa M Husain, Rebecca G Knapp, Georgios Petrides, Matthew V Rudorfer, Robert C Young, Shawn M McClintock, Martina Mueller, Joan Prudic, Robert M Greenberg, Richard D Weiner, Samuel H Bailine, Nagy A Youssef, Laryssa McCloud, Charles H Kellner
We examined whether electroconvulsive therapy (ECT) plus medications ("STABLE + PHARM" group) had superior HRQOL compared with medications alone ("PHARM" group) as continuation strategy after successful acute right unilateral ECT for major depressive disorder (MDD). We hypothesized that scores from the Medical Outcomes Study Short Form-36 (SF-36) would be higher during continuation treatment in the "STABLE + PHARM" group versus the "PHARM" group. The overall study design was called "Prolonging Remission in Depressed Elderly" (PRIDE)...
November 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29157801/corrigendum-to-structure-and-pharmaceutical-formulation-development-of-a-new-long-acting-recombinant-human-insulin-analog-studied-by-nmr-and-ms-j-pharm-biomed-anal-135-2017-126-132
#6
Elżbieta Bednarek, Jerzy Sitkowski, Wojciech Bocian, Piotr Borowicz, Grażyna Płucienniczak, Dorota Stadnik, Weronika Surmacz-Chwedoruk, Beata Jaworska, Lech Kozerski
No abstract text is available yet for this article.
January 30, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29150175/-erratum-to-synthesis-and-binding-affinity-to-human-steroid-hormone-receptors-of-3-phenoxy-4-hydroxycoumarins-and-3-phenoxy-4-phenylcoumarins-ann-pharm-fr-2017-75-455-462
#7
R Bakhchinian, F Bouchoux, S Kirkiacharian
No abstract text is available yet for this article.
November 14, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29144022/collagen-a-review-on-its-sources-and-potential-cosmetic-applications
#8
REVIEW
María Isabela Avila Rodríguez, Laura G Rodríguez Barroso, Mirna Lorena Sánchez
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. It has been established that the collagen fibers are damaged with the pass of time, losing thickness and strength which has been strongly related with skin aging phenomena [Colágeno para todo...
November 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29080846/safety-against-nephrotoxicity-in-paclitaxel-treatment-oral-nanocarrier-as-an-effective-tool-in-preclinical-evaluation-with-marked-in-vivo-antitumor-activity
#9
Hira Choudhury, Bapi Gorain, Rakesh Kumar Tekade, Manisha Pandey, Sanmoy Karmakar, Tapan Kumar Pal
Oral paclitaxel (PTXL) formulations freed from cremophor® EL (CrEL) is always in utmost demand by the cancerous patients due to toxicities associated with the currently marketed formulation. In our previous investigation [Int. J. Pharm. 2014; 460:131], we have developed an oral oil based nanocarrier for the lipophilic drug, PTXL to target bioavailability issue and patient compliance. Here, we report in vivo antitumor activity and 28-day sub-chronic toxicity of the developed PTXL nanoemulsion. It was observed that the apoptotic potential of oral PTXL nanoemulsion significantly inhibited the growth of solid tumor (59...
December 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29079370/impact-of-an-emergency-medicine-pharmacist-on-initial-antibiotic-prophylaxis-for-open-fractures-in-trauma-patients
#10
Somer Harvey, A Brad Hall, Kayla Wilson
BACKGROUND: Targeted antibiotic treatment reduces the infection risk of open fractures when soft tissue and bone are exposed to the environment. The risk of infection increases with higher degrees of injury. The Gustilo-Anderson system was developed to identify the degree of injury of open fractures and can be utilized to guide initial antibiotic therapy. Few studies have been published evaluating the potential impact of emergency medicine pharmacists in trauma, and currently no study has evaluated a pharmacist's influence on antibiotic selection and timing for open fractures...
October 17, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29029668/the-de-pharm-project-a-pharmacist-driven-deprescribing-initiative-in-a-nursing-facility
#11
Jennifer Pruskowski, Steven M Handler
OBJECTIVE: Many residents with life-limiting illnesses are being prescribed and taking potentially inappropriate medications (PIMs) and questionably beneficial medications either near or at the end of life. These medications can contribute to adverse drug reactions, increase morbidity, and increase unnecessary burden and cost. It is crucial that the process of deprescribing be incorporated into the care of these residents. After developing a clinical pharmacist-driven deprescribing initiative in the nursing facility, the objective of this project was to reduce the number of PIMs via accepted recommendations from the clinical pharmacist to the primary team...
August 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28991203/pharmacy-practice-and-education-in-the-czech-republic
#12
Petr Nachtigal, Tomáš Šimůnek, Jeffrey Atkinson
The PHARMINE ("Pharmacy Education in Europe") project studied the organisation of pharmacy education, practice and legislation in the European Union (EU) with the objectives of evaluating to what degree harmonisation had taken place with the EU, and producing documents on each individual EU member state. Part of this work was in the form of a survey of pharmacy education, practice, and legislation in the various member states. We will publish the individual member state surveys as reference documents. This paper presents the results of the PHARMINE survey on pharmacy education, training, and practice in the Czech Republic...
October 9, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28985194/current-status-of-blood-pharming-megakaryoctye-transfusions-as-a-source-of-platelets
#13
Kandace Gollomp, Michele P Lambert, Mortimer Poncz
PURPOSE OF REVIEW: Donor-derived platelets have proven to be of hemostatic value in many clinical settings. There is a fear that the need for platelets may outgrow the donor pool in first-world countries. Moreover, there are other challenges with donor platelets that add to the impetus to find an alternative platelet source, especially after the megakaryocyte cytokine thrombopoietin was identified. Megakaryocytes have since been differentiated from numerous cell sources and the observed released platelet-like particles (PLPs) have led to calls to develop such products for clinical use...
November 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/28980237/avian-biotechnology
#14
Yoshiaki Nakamura
Primordial germ cells (PGCs) generate new individuals through differentiation, maturation and fertilization. This means that the manipulation of PGCs is directly linked to the manipulation of individuals, making PGCs attractive target cells in the animal biotechnology field. A unique biological property of avian PGCs is that they circulate temporarily in the vasculature during early development, and this allows us to access and manipulate avian germ lines. Following the development of a technique for transplantation, PGCs have become central to avian biotechnology, in contrast to the use of embryo manipulation and subsequent transfer to foster mothers, as in mammalian biotechnology...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28970607/adaptation-and-validation-of-the-fresno-test-of-competence-in-evidence-based-medicine-in-doctor-of-pharmacy-students
#15
Valerie Coppenrath, Lee Anne Filosa, Elizabeth Akselrod, Katherine M Carey
Objective. To adapt and validate an instrument assessing competence in evidence-based medicine (EBM) in Doctor of Pharmacy students. Methods. The Fresno test was validated in medical residents. We adapted it for use in pharmacy students. A total of 120 students and faculty comprised the validation set. Internal reliability, item difficulty, and item discrimination were assessed. Construct validity was assessed by comparing mean total scores of students to faculty, and comparing proportions of students and faculty who passed each item...
August 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28970458/current-status-and-future-suggestions-for-improving-the-pharm-d-curriculum-towards-clinical-pharmacy-practice-in-pakistan
#16
Saima Mahmood Malhi, Hassan Raza, Kiran Ajmal, Sumbul Shamim, Saniya Ata, Salman Farooq, Syed Muhammad Sharib, Sidrat-Ul Muntaha
Objectives & Background: Good curriculum is reflected as the backbone for standard universities to develop competitive professionals having great potential. Pharmacy education in Pakistan has gone through the same developmental stages as in other countries, but is still striving for improvement. In the present study, we want (i) to know the opinion on whether the current pharmacy curriculum requires any improvement in order to meet the training needs of pharmacy professionals regarding clinical knowledge and pharmacy practice; and (ii) to present some humble suggestions to decision-making authorities in order to improve it with respect to patient-focused programs (PFP)...
August 17, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28970446/pharmacy-practice-and-education-in-bulgaria
#17
Valentina Petkova, Jeffrey Atkinson
Pharmacies in Bulgaria have a monopoly on the dispensing of medicinal products that are authorized in the Republic of Bulgaria, as well as medical devices, food additives, cosmetics, and sanitary/hygienic articles. Aptekari (pharmacists) act as responsible pharmacists, pharmacy owners, and managers. They follow a five year Masters of Science in Pharmacy (M.Sc. Pharm.) degree course with a six month traineeship. Pomoshnik-farmacevti (assistant pharmacists) follow a three year degree with a six month traineeship...
June 22, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28969929/ibutilide-effectiveness-and-safety-in-the-cardioversion-of-atrial-fibrillation-and-flutter-in%C3%A2-the-community-emergency-department
#18
David R Vinson, Nelya Lugovskaya, E Margaret Warton, Aaron M Rome, Matthew D Stevenson, Mary E Reed, Manvi R Nagam, Dustin W Ballard
STUDY OBJECTIVE: Little is known about the use of ibutilide for cardioversion in atrial fibrillation and flutter outside of clinical trials. We seek to describe patient characteristics, ibutilide administration patterns, cardioversion rates, and adverse outcomes in the community emergency department (ED) setting. We also evaluate potential predictors of cardioversion success. METHODS: Using a retrospective cohort of adults who received ibutilide in 21 community EDs between January 2009 and June 2015, we gathered demographic and clinical variables from electronic health records and structured manual chart review...
September 29, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28968723/ccfold-rapid-and-accurate-prediction-of-coiled-coil-structures-and-application-to-modeling-intermediate-filaments
#19
Dmytro Guzenko, Sergei V Strelkov
Motivation: Accurate molecular structure of the protein dimer representing the elementary building block of intermediate filaments (IFs) is essential towards the understanding of the filament assembly, rationalizing their mechanical properties and explaining the effect of disease-related IF mutations. The dimer contains a ~300-residue long α-helical coiled coil which cannot be assessed by either direct experimental structure determination or modelling using standard approaches. At the same time, coiled coils are well-represented in structural databases...
September 4, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28952490/photocurable-bioink-for-the-inkjet-3d-pharming-of-hydrophilic-drugs
#20
Giovanny F Acosta-Vélez, Chase S Linsley, Madison C Craig, Benjamin M Wu
Novel strategies are required to manufacture customized oral solid dosage forms for personalized medicine applications. 3D Pharming, the direct printing of pharmaceutical tablets, is an attractive strategy, since it allows for the rapid production of solid dosage forms containing custom drug dosages. This study reports on the design and characterization of a biocompatible photocurable pharmaceutical polymer for inkjet 3D printing that is suitable for hydrophilic active pharmaceutical ingredients (API). Specifically, hyaluronic acid was functionalized with norbornene moieties that, in the presence of poly(ethylene) glycol dithiol, Eosin Y as a photoinitiator, and a visible light source, undergoes a rapid step-growth polymerization reaction through thiol-ene chemistry...
January 28, 2017: Bioengineering
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