R Bergholm, S Mäkimattila, M Valkonen, M L Liu, S Lahdenperä, M R Taskinen, A Sovijärvi, P Malmberg, H Yki-Järvinen
Physical training increases free radical production and consumes antioxidants. It has previously been shown that acute exercise markedly increases the susceptibility of LDL to oxidation but whether such changes are observed during physical training is unknown. We measured circulating antioxidants, lipids and lipoproteins, and blood flow responses to intrabrachial infusions of endothelium-dependent (acetylcholine, ACh, L-N-monomethyl-arginine, L-NMMA) and -independent (sodium nitroprusside, SNP) vasoactive agents, before and after 3 months of running in 9 fit male subjects...
August 1999: Atherosclerosis