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https://www.readbyqxmd.com/read/28104012/-simultaneous-triple-semicircular-canal-plugging-and-cochlear-implantation-in-advanced-meniere-s-disease
#1
D G Zhang, L Xu, Y C Han, Y F Lyu, J F Luo, Y W Li, R J Wang, Z M Fan, H B Wang
Objective: To evaluate the feasibility of combining simultaneous triple semicircular canal plugging (TSCP) and cochlear implantation (CI) to treat vertigo and hearing loss in advanced Meniere's disease(MD) patients, so as to provide an alternative surgical procedure for treating this disorder. Methods: Data from seven patients, who were referred to our hospital and diagnosed with unilateral MD strictly meeting the criteria issued by Chinese Academy of Otolaryngology-Head and Neck Surgery Committee (2006), from Jan...
January 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28100858/-semi-quantitative-assessment-of-tinnitus-before-and-after-endovascular-treatment-for-intracranial-dural-arteriovenous-fistula-usefulness-of-the-tinnitus-handicap-inventory-thi-score
#2
Keitaro Shiraishi, Naoki Akioka, Daina Kashiwazaki, Naoya Kuwayama, Satoshi Kuroda
Intracranial dural arteriovenous fistulas(dAVFs)cause pulsatile tinnitus that can easily impair the individual's quality of life. In this study, we aimed to assess the usefulness of the semi-quantitative Tinnitus Handicap Inventory(THI)score before and after endovascular treatment in patients with intracranial dAVF by determining the relationship between the severity of pulsatile tinnitus, radiographic findings, and the effect of treatment. This study included a total of 14 sides in 13 patients who underwent endovascular therapy for pulsatile tinnitus due to intracranial dAVFs between March 2014 and September 2015...
January 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28099967/somatosensory-tinnitus-correlation-between-cranio-cervico-mandibular-disorder-history-and-somatic-modulation
#3
Massimo Ralli, Giancarlo Altissimi, Rosaria Turchetta, Filippo Mazzei, Massimo Salviati, Francesca Cianfrone, Maria Patrizia Orlando, Valeria Testugini, Giancarlo Cianfrone
In a subpopulation of patients, tinnitus can be modulated by movements of the jaw or head and neck due to complex somatosensory-auditory interactions. In some of these subjects, tinnitus could be related to an underlying temporomandibular (TMJ) or craniocervical (NECK) dysfunction that, if correctly identified, could streamline treatment and increase chances of tinnitus improvement. However, it is still unclear whether somatic modulation of tinnitus could be used as a screening tool for identifying such patients...
January 19, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28097918/the-hearing-benefit-of-cochlear-implantation-for-individuals-with-unilateral-hearing-loss-but-no-tinnitus
#4
Henryk Skarzynski, Artur Lorens, Marika Kruszynska, Anita Obrycka, Dorota Pastuszak, Piotr Henryk Skarzynski
CONCLUSION: Cochlear implants improve the hearing abilities of individuals with unilateral hearing loss and no tinnitus. The benefit is no different from that seen in patients with unilateral hearing loss and incapacitating tinnitus. OBJECTIVE: To evaluate hearing outcomes after cochlear implantation in individuals with unilateral hearing loss and no tinnitus and compare them to those obtained in a similar group who had incapacitating tinnitus. METHODS: Six cases who did not experience tinnitus before operation and 15 subjects with pre-operative tinnitus were evaluated with a structured interview, a monosyllabic word test under difficult listening situations, a sound localization test, and an APHAB (abbreviated profile of hearing aid benefit) questionnaire...
January 18, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28089417/venous-sinus-compromise-after-pre-sigmoid-transpetrosal-approach-for-skull-base-tumors-a-study-on-the-asymptomatic-incidence-and-report-of-a-rare-dural-arteriovenous-fistula-as-symptomatic-manifestation
#5
Walter C Jean, Daniel R Felbaum, Andrew B Stemer, Michael Hoa, H Jeffrey Kim
The sigmoid sinus is routinely exposed and manipulated during pre-sigmoid, transpetrosal approaches to the skull base, but there is scant data available on the incidence of venous sinus compromise after surgery. We encountered a dural arteriovenous fistula as a result of sigmoid sinus occlusion and examined the incidence of venous sinus thrombosis or narrowing after transpetrosal surgeries. We performed a retrospective analysis of a series of patients treated by the senior surgeons (WCJ, MH, HJK), who underwent either a posterior petrosectomy or translabyrinthine approach for various skull base tumors...
January 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28089238/ruxolitinib-for-symptom-control-in-patients-with-chronic-lymphocytic-leukaemia-a-single-group-phase-2-trial
#6
Preetesh Jain, Michael Keating, Sarah Renner, Charles Cleeland, Huang Xuelin, Graciela Nogueras Gonzalez, David Harris, Ping Li, Zhiming Liu, Ivo Veletic, Uri Rozovski, Nitin Jain, Phillip Thompson, Prithviraj Bose, Courtney DiNardo, Alessandra Ferrajoli, Susan O'Brien, Jan Burger, William Wierda, Srdan Verstovsek, Hagop Kantarjian, Zeev Estrov
BACKGROUND: Disease-related symptoms impair the quality of life of patients with chronic lymphocytic leukaemia (CLL) who do not require systemic therapy. Available therapies are not specifically aimed at symptom control. Because stimulation of the B-cell receptor activates JAK2 in CLL cells and the JAK2 inhibitor ruxolitinib improves symptoms in patients with myelofibrosis, we postulated that ruxolitinib would improve disease-related symptoms in patients with CLL. We did a phase 2 trial of ruxolitinib to test this hypothesis...
January 11, 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28089173/use-of-interactive-ibooks-for-patient-education-in-otology
#7
Omid Moshtaghi, Yarah M Haidar, Ronald Sahyouni, Ramin Rajaii, Afsheen Moshtaghi, Amin Mahmoodi, Yaser Ghavami, Harrison W Lin, Hamid R Djalilian
INTRODUCTION: Physicians in the ambulatory setting face challenges in adequately educating patients in a brief office encounter. OBJECTIVE: To evaluate the efficacy of an iPad-based interactive educational module (iBook) in various otologic pathologies. METHODS: Patients presenting with symptoms of tinnitus, dizziness, hearing loss, or cochlear implant evaluation were included. In total, 44 patients received the iBook and 22 patients served as controls...
December 29, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28087419/cochlear-synaptopathy-in-acquired-sensorineural-hearing-loss-manifestations-and-mechanisms
#8
REVIEW
M Charles Liberman, Sharon G Kujawa
Common causes of hearing loss in humans - exposure to loud noise or ototoxic drugs and aging - often damage sensory hair cells, reflected as elevated thresholds on the clinical audiogram. Recent studies in animal models suggest, however, that well before this overt hearing loss can be seen, a more insidious, but likely more common, process is taking place that permanently interrupts synaptic communication between sensory inner hair cells and subsets of cochlear nerve fibers. The silencing of affected neurons alters auditory information processing, whether accompanied by threshold elevations or not, and is a likely contributor to a variety of perceptual abnormalities, including speech-in-noise difficulties, tinnitus and hyperacusis...
January 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/28077744/neuropsychiatric-outcomes-after-mefloquine-exposure-among-u-s-military-service-members
#9
Angelia A Eick-Cost, Zheng Hu, Patricia Rohrbeck, Leslie L Clark
Mefloquine was widely prescribed to U.S. military service members until 2009 when use was limited to personnel with contraindications to doxycycline and no contraindications to mefloquine. The need to estimate the occurrence of neuropsychiatric outcomes (NPOs) in service members prescribed mefloquine warranted a comprehensive evaluation of this issue. Active component service members filling a prescription for mefloquine, doxycycline, or atovaquone/proguanil (A/P) between January 1, 2008 and June 30, 2013, were included in the analysis...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28076681/computational-modeling-of-neurotransmitter-release-evoked-by-electrical-stimulation-non-linear-approaches-to-predicting-stimulation-evoked-dopamine-release
#10
James K Trevathan, Ali Yousefi, Hyung Ook Park, John J Bartoletta, Kip A Ludwig, Kendall H Lee, J Luis Lujan
Neurochemical changes evoked by electrical stimulation of the nervous system have been linked to both therapeutic and undesired effects of neuromodulation therapies used to treat obsessive-compulsive disorder, depression, epilepsy, Parkinson's disease, stroke, hypertension, tinnitus, and many other indications. In fact, interest in better understanding the role of neurochemical signaling in neuromodulation therapies has been a focus of recent government- and industry-sponsored programs whose ultimate goal is to usher in an era of personalized medicine by creating neuromodulation therapies that respond to real-time changes in patient status...
January 11, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28072813/a-case-report-on-red-ear-syndrome-with-tinnitus-successfully-treated-with-transcranial-random-noise-stimulation
#11
Peter M Kreuzer, Veronika Vielsmeier, Timm B Poeppl, Berthold Langguth
BACKGROUND: The red ear syndrome represents a rare symptom complex consisting of auricular erythema associated with painful and burning sensations. It has been described in combination with tinnitus rarely. It has been hypothesized to be etiologically related to altered trigeminal afferent input, temporomandibular disorders, and thalamic dysfunction. OBJECTIVES: The initial objective of applying transcranial random noise stimulation (tRNS) in a case of red ear syndrome in combination with tinnitus was the alleviation of the phantom sounds...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28068305/comparison-of-treatment-outcomes-following-either-prefrontal-cortical-only-or-dual-site-repetitive-transcranial-magnetic-stimulation-in-chronic-tinnitus-patients-a-double-blind-randomized-study
#12
Tae-Soo Noh, Jeong Sug Kyong, Mun Young Chang, Moo-Kyun Park, Jun-Ho Lee, Seung-Ha Oh, June Sic Kim, Chun Kee Chung, Myung-Whan Suh
OBJECTIVES: We evaluated treatment outcomes following single-site repetitive transcranial magnetic stimulation (rTMS) in the dorsolateral prefrontal cortex (DLPFC) and dual-site rTMS in the auditory cortex (AC) and DLPFC (AC + FC). STUDY DESIGN AND PATIENTS: This prospective randomized double-blind trial initially included 19 patients with chronic tinnitus and 17 of these patients received rTMS on the left AC and left DLPFC or only the left DLPFC. The subjects were randomly allocated to either the dual-site rTMS (AC + FC) protocol (Group 1, n = 9) or the singlesite rTMS (DLPFC) protocol (Group 2, n = 8)...
February 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28062999/relationship-between-increased-carotid-artery-stiffness-and-idiopathic-subjective-tinnitus
#13
C Bayraktar, S Taşolar
Tinnitus is defined as perception of sound with no external stimulus, and can separate into pulsatile and non-pulsatile types. Arterial stiffness is a parameter that can predict the cardiovascular event and associated with incidence of stroke. It has been shown that increased arterial stiffness may lead to microvascular damage in brain. Our aim was to assess the arterial stiffness of the carotid system in the development and severity of idiopathic subjective tinnitus. Forty subjective tinnitus patients and 40 age- and sex-matched controls were enrolled in the study...
January 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28062802/moving-target-transient-rotational-stenosis-precipitating-jugular-bow-hunter-s-syndrome
#14
Waleed Brinjikji, Christopher S Graffeo, Avital Perry, Terence Zimmerman, Jeffrey R Janus, Pearce P Morris, Gregory D Cascino, Giuseppe Lanzino
A 60-year-old man presented with a 10-month history of of stereotypical spells characterized by vertigo, tinnitus, blurred vision, left hemibody numbness, and occasional syncope, precipitated by turning his head leftwards. Cerebral angiography and CT angiography of the head and neck with provocative maneuvers did not demonstrate vertebral artery narrowing. However, there was narrowing of the left internal jugular vein due to extrinsic compression from the sternocleidomastoid with leftward head rotation in the setting of hypoplasia of the right internal jugular vein...
January 6, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28057614/a-case-of-pulsatile-tinnitus
#15
Karan Jolly, Pawanjit Hare, Richard Irving, Peter Monksfield
No abstract text is available yet for this article.
January 5, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28057352/sigmoid-sinus-cortical-plate-dehiscence-induces-pulsatile-tinnitus-through-amplifying-sigmoid-sinus-venous-sound
#16
Shan Tian, Lizhen Wang, Jiemeng Yang, Rui Mao, Zhaohui Liu, Yubo Fan
Sigmoid sinus cortical plate dehiscence (SSCPD) is common in pulsatile tinnitus (PT) patients, and is treated through SSCPD resurfacing surgery in clinic, but the bio-mechanism is not clear as so far. This study aimed to clarify the bio-mechanism of PT sensation induced by SSCPD, and quantify the relationship of cortical plate (CP) thickness and PT sensation intensity. It was hypothesized that SSCPD would induce PT through significantly amplifying sigmoid sinus (SS) venous sound in this study. Finite element (FE) analysis based on radiology data of typical patient was used to verify this hypothesis, and was validated with clinical reports...
December 16, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28057349/flow-patterns-in-the-jugular-veins-of-pulsatile-tinnitus-patients
#17
Evan Kao, Sarah Kefayati, Matthew R Amans, Farshid Faraji, Megan Ballweber, Van Halbach, David Saloner
Pulsatile Tinnitus (PT) is a pulse-synchronous sound heard in the absence of an external source. PT is often related to abnormal flow in vascular structures near the cochlea. One vascular territory implicated in PT is the internal jugular vein (IJV). Using computational fluid dynamics (CFD) based on patient-specific Magnetic Resonance Imaging (MRI), we investigated the flow within the IJV of seven subjects, four symptomatic and three asymptomatic of PT. We found that there were two extreme anatomic types classified by the shape and position of the jugular bulbs: elevated and rounded...
December 14, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28053240/broadened-population-level-frequency-tuning-in-the-auditory-cortex-of-tinnitus-patients
#18
Kenichi Sekiya, Mariko Takahashi, Shingo Murakami, Ryusuke Kakigi, Hidehiko Okamoto
Tinnitus is a phantom auditory perception without an external sound source and is one of the most common public health concerns that impair the quality of life of many individuals. However, its neural mechanisms remain unclear. We herein examined population-level frequency tuning in the auditory cortex of unilateral tinnitus patients with similar hearing levels in both ears using magnetoencephalography. We compared auditory evoked neural activities elicited by a stimulation to the tinnitus and non-tinnitus ears...
January 4, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28050631/head-to-head-comparison-between-18-f-fdopa-pet-ct-and-mr-ct-angiography-in-clinically-recurrent-head-and-neck-paragangliomas
#19
Céline Heimburger, Francis Veillon, David Taïeb, Bernard Goichot, Sophie Riehm, Julie Petit-Thomas, Gerlinde Averous, Marcela Cavalcanti, Fabrice Hubelé, Gerard Chabrier, Izzie Jacques Namer, Anne Charpiot, Alessio Imperiale
PURPOSE: Head and neck paragangliomas (HNPGLs) can relapse after primary treatment. Optimal imaging protocols have not yet been established for posttreatment evaluation. The aim of the present study was to assess the diagnostic value of (18)F-FDOPA PET/CT and MR/CT angiography (MRA/CTA) in HNPGL patients with clinical relapse during their follow-up. METHODS: Sixteen consecutive patients presenting with local pain, tinnitus, dysphagia, hoarse voice, cranial nerve involvement, deafness, or retrotympanic mass appearing during follow-up after the initial treatment of HNPGLs were retrospectively evaluated...
January 3, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28050210/tinnitus-in-elderly-individuals-discomfort-and-impact-in-the-quality-of-life
#20
Adriane Ribeiro Teixeira, Leticia Petersen Schmidt Rosito, Andréa Kruger Gonçalves, Michelle Gassen Paulo Nunes, Silvia Dornelles, Maira Rozenfeld Olchik
Introduction Tinnitus is a symptom that affects mainly the elderly and can negatively influence their quality of life. Objective The objective of our study is to evaluate the existence of a relationship between the quality of life and the impact caused by tinnitus in elderly individuals, considering the age and gender variables. Method We conducted a cross-sectional study in elderly people of both genders who participate in the extension activities at the university. The evaluation was composed of anamnesis and WHOQOL-OLD instruments, to evaluate the quality of life, and Tinnitus Handicap Inventory (THI) for the evaluation of the tinnitus impact...
January 2017: International Archives of Otorhinolaryngology
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