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https://www.readbyqxmd.com/read/28925013/an-animal-model-of-deep-brain-stimulation-for-treating-tinnitus-a-proof-of-concept-study
#1
Syed F Ahsan, Hao Luo, Jinsheng Zhang, Eric Kim, Yong Xu
OBJECTIVE: This proof-of-concept study aimed to demonstrate therapeutic effects of deep brain stimulation (DBS) on noise-induced tinnitus. STUDY DESIGN: Experimental animal study. METHODS: After Institutional Animal Care and Use Committee approval, nine adult rats were implanted in the caudate nucleus with custom-made electrode array. The rats were exposed to noise to induce tinnitus. Auditory brainstem response was performed to evaluate hearing threshold changes...
September 19, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28923485/functional-data-analysis-of-single-trial-auditory-evoked-potentials-recorded-in-the-awake-rat
#2
Ondrej Pokora, Jan Kolaicek, Tzai-Wen Chiu, Wei Qiu
Evoked potentials (EPs) reflect neural processing and are widely used to study sensory perception. However, methods of analyzing EP have been limited mostly to the conventional ensemble averaging of EP response trials to a repeated stimulus, and less so to single-trials analysis. Here we applied a new approach - functional data analysis (FDA) - to study auditory EP in the rat model of tinnitus, in which overdoses of salicylate (SS) are known to alter sound perception characteristically, as the same way as in humans...
September 15, 2017: Bio Systems
https://www.readbyqxmd.com/read/28922875/stent-placement-for-disabling-pulsatile-tinnitus-caused-by-a-lateral-sinus-stenosis-a-retrospective-study
#3
Stéphanie Lenck, Marc-Antoine Labeyrie, Fabrice Vallee, Jean-Pierre Saint-Maurice, Antoine Guillonnet, Anne-Laure Bernat, Pierre Vironneau, Emmanuel Houdart
BACKGROUND: Lateral sinus stenosis is a little-known cause for pulsatile tinnitus (PT). In several small series, stenting has been described as an effective treatment for disabling PT linked with this type of stenosis. OBJECTIVES: To describe the clinical, radiological, and manometric characteristics of patients treated for disabling PT by lateral sinus stenosis. Assessment of the efficacy of stenting for this indication. METHODS: Retrospective study of patients treated for isolated PT by stenting of a lateral sinus stenosis in our institution, between 2009 and 2015...
October 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28918676/cross-cultural-adaptation-and-psychometric-properties-of-the-chinese-tinnitus-functional-index
#4
Anna Chi Shan Kam, Eric Kwok Shun Leung, Patrick Yiu Bong Chan, Michael Chi Fai Tong
OBJECTIVES: To establish the reliability, validity and responsiveness of the Chinese version of the Tinnitus Functional Index (TFI-CH) in measuring tinnitus severity in Hong Kong Chinese population. DESIGN: This is a cross-sectional psychometric validation study. STUDY SAMPLE: Subjects were 124 adult Chinese who attended the audiology clinics in a hospital setting for tinnitus treatment. RESULTS: The TFI-CH showed good internal consistency reliability (α = 0...
September 18, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28914488/a-hebrew-adaptation-of-the-tinnitus-functional-index
#5
Yahav Oron, Shay Shemesh, Sharon Ovnat Tamir, Abraham Goldfarb, Tal Marom, Ofer Gluck, Sagit Shushan
Tinnitus is the perception of sounds, when no external stimuli exists. Its prevalence has been estimated to be between 8% and 30% in the general population (1). Some patients describe intrusive tinnitus which affects many aspects of their lives, while others describe an insignificant disturbance caused by the tinnitus (2). Since tinnitus is a subjective symptom in most cases, defining its effect on patients' lives can be challenging. Several questionnaires have been developed in order to characterize the effects of tinnitus on patients' lives...
September 15, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28910557/vogt-koyanagi-harada-syndrome-in-a-group-of-patients-in-two-ophthalmology-referral-centers-in-bogot%C3%A3-colombia
#6
Carol L Guayacán, Brahyan Galindo-Mendez, Alejandra de-la-Torre
PURPOSE: To describe the clinical presentation of Vogt-Koyanagi-Harada (VKH) syndrome in a group of patients in Colombia. METHODS: Retrospective review of 2638 medical records of patients with uveitis in two centers during 17 years. RESULTS: A total of 25 patients with uveitis were diagnosed with VKH syndrome (0.95%), 23 patients were included in the data analysis (0.87%), 78.3% females, and mean age of diagnosis was 37 years (SD ± 29)...
September 14, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28906245/potential-audiological-and-mri-markers-of-tinnitus
#7
Kamakshi V Gopal, Binu P Thomas, Rajesh Nandy, Deng Mao, Hanzhang Lu
BACKGROUND: Subjective tinnitus, or ringing sensation in the ear, is a common disorder with no accepted objective diagnostic markers. PURPOSE: The purpose of this study was to identify possible objective markers of tinnitus by combining audiological and imaging-based techniques. RESEARCH DESIGN: Case-control studies. STUDY SAMPLE: Twenty adults drawn from our audiology clinic served as participants. The tinnitus group consisted of ten participants with chronic bilateral constant tinnitus, and the control group consisted of ten participants with no history of tinnitus...
September 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28906162/effects-of-tinnitus-treatments-on-sleep-disorders-in-patients-with-tinnitus
#8
Satoko Wakabayashi, Hideyuki Saito, Naoki Oishi, Seiichi Shinden, Kaoru Ogawa
OBJECTIVE: To assess the effects of tinnitus treatments on sleep disorders in patients with tinnitus. DESIGN: Subjects completed the Pittsburg Sleep Quality Index (PSQI), Tinnitus Handicap Inventory (THI), Self-rating Depression Scale (SDS), and State Trait Anxiety Inventory (STAI). The questionnaire results and the patients' sex, age, time since the onset of tinnitus, and mean hearing level were examined, and differences between a sleep disorder group and a normal sleep group were examined...
September 14, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28902804/long-term-patient-reported-outcomes-after-surgery-for-superior-canal-dehiscence-syndrome
#9
Mohammed S Alkhafaji, Sanskriti Varma, Seth E Pross, Jeffrey D Sharon, Jason C Nellis, Charles C Della Santina, Lloyd B Minor, John P Carey
OBJECTIVE: Evaluate the long-term patient-reported outcomes of surgery for superior canal dehiscence syndrome (SCDS). STUDY DESIGN: Cross-sectional survey. SETTING: Tertiary referral center. PATIENTS: Adults who have undergone surgery for SCDS with at least 1 year since surgery. MAIN OUTCOME MEASURE(S): Primary outcome: change in symptoms that led to surgery. SECONDARY OUTCOMES: change in 11 SCDS-associated symptoms, change in psychosocial metrics, and willingness to recommend surgery to friends with SCDS...
October 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28902460/arabic-validation-of-the-tinnitus-handicap-inventory-and-the-mini-tinnitus-questionnaire-on-100-adult-patients
#10
Marc El Beaino, Elie Eter
Arabic formats of tinnitus questionnaires are needed to provide clinicians and researchers responsive and reliable tools to assess tinnitus. Arabic versions of the Tinnitus Handicap Inventory and the Mini-Tinnitus Questionnaire are established. Tinnitus Handicap Inventory and Mini-Tinnitus Questionnaire are reliable and valid tools for tinnitus assessment. Tinnitus Handicap Inventory and Mini-Tinnitus Questionnaire are correlated. Mini-Tinnitus Questionnaire is a quicker and more compact method of evaluating tinnitus compared to Tinnitus Handicap Inventory...
September 13, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28900863/metal-on-metal-hip-joint-prostheses-a-retrospective-case-series-investigating-the-association-of-systemic-toxicity-with-serum-cobalt-and-chromium-concentrations
#11
James H Ho, Jerrold B Leikin, Paul I Dargan, John R H Archer, David M Wood, Jeffrey Brent
INTRODUCTION: There have been concerns about prosthesis failure and the potential for systemic toxicity due to release of cobalt and chromium from metal-on-metal hip joint prostheses (MoM-HP). There is conflicting evidence on whether there is a correlation between higher cobalt and chromium concentrations and systemic toxicity. METHODS: We undertook a retrospective review of consecutive patients with MoM-HP referred for outpatient review in toxicology clinics in London, UK, and in the USA recorded in the Toxicology Investigators Consortium (ToxIC) Registry from June 2011 to June 2015...
September 12, 2017: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/28894836/the-effect-of-tinnitus-retraining-therapy-on-chronic-tinnitus-a-controlled-trial
#12
Carol A Bauer, Jennifer L Berry, Thomas J Brozoski
OBJECTIVES: The goal of this study was to compare treatment outcomes for chronic bothersome tinnitus after Tinnitus Retraining Therapy (TRT) versus standard of care treatment (SC) and to determine the longevity of the effect over an 18-month period. STUDY DESIGN: A randomized controlled trial comparing TRT to SC for chronic tinnitus. METHODS: Adults with subjective, stable, bothersome chronic tinnitus associated with hearing loss amenable to aural rehabilitation with hearing aids were recruited...
August 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28894434/tinnitus-patients-with-comorbid-headaches-the-influence-of-headache-type-and-laterality-on-tinnitus-characteristics
#13
Berthold Langguth, Verena Hund, Michael Landgrebe, Martin Schecklmann
BACKGROUND: Both clinical experience and clinical studies suggest a relationship between tinnitus and headache. Here, we aimed to investigate the influence of comorbid headache type and headache laterality on tinnitus characteristics. METHOD: The Tinnitus Research Initiative database was screened for patients of the Tinnitus Center of the University Regensburg who reported comorbid headaches. These patients were contacted to complete additional validated questionnaires...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28892822/audiometric-testing-with-pulsed-steady-and-warble-tones-in-listeners-with-tinnitus-and-hearing-loss
#14
Jennifer J Lentz, Matthew A Walker, Ciara E Short, Kimberly G Skinner
Purpose: This study evaluated the American Speech-Language-Hearing Association's recommendation that audiometric testing for patients with tinnitus should use pulsed or warble tones. Using listeners with varied audiometric configurations and tinnitus statuses, we asked whether steady, pulsed, and warble tones yielded similar audiometric thresholds, and which tone type was preferred. Method: Audiometric thresholds (octave frequencies from 0.25-16 kHz) were measured using steady, pulsed, and warble tones in 61 listeners, who were divided into 4 groups on the basis of hearing and tinnitus status...
September 18, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28888426/sudden-sensorineural-hearing-loss-in-children-and-adolescents-clinical-characteristics-and-age-related-prognosis
#15
Jin Youp Kim, Jae Joon Han, Woong Sang Sunwoo, Ja-Won Koo, Seung-Ha Oh, Min-Hyun Park, Young Ho Kim
OBJECTIVE: Although many studies have investigated sudden sensorineural hearing loss (SSNHL) in adults, there were few studies on SSNHL in the pediatric population; especially research on treatment and prognosis of pediatric SSNHL was limited. The aim of this study was to evaluate clinical characteristics, treatment outcomes and prognostic factors in children and adolescents with SSNHL. METHODS: A retrospective review of medical records of 67 pediatric patients (67 ears) who had diagnosed with SSNHL at our hospitals was performed to analyze patients' clinical manifestations and audiograms...
September 6, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28886123/increased-medial-olivocochlear-reflex-strength-in-normal-hearing-noise-exposed-humans
#16
Ishan Bhatt
Research suggests that college-aged adults are vulnerable to tinnitus and hearing loss due to exposure to traumatic levels of noise on a regular basis. Recent human studies have associated exposure to high noise exposure background (NEB, i.e., routine noise exposure) with the reduced cochlear output and impaired speech processing ability in subjects with clinically normal hearing sensitivity. While the relationship between NEB and the functions of the auditory afferent neurons are studied in the literature, little is known about the effects of NEB on functioning of the auditory efferent system...
2017: PloS One
https://www.readbyqxmd.com/read/28885581/work-related-noise-exposure-in-a-cohort-of-patients-with-chronic-tinnitus-analysis-of-demographic-and-audiological-characteristics
#17
Massimo Ralli, Maria Paola Balla, Antonio Greco, Giancarlo Altissimi, Pasquale Ricci, Rosaria Turchetta, Armando de Virgilio, Marco de Vincentiis, Serafino Ricci, Giancarlo Cianfrone
Work-related noise exposure is one of the major factors contributing to the development of adult-onset hearing loss and tinnitus. The aim of this study was to analyze, in patients with chronic tinnitus and long-term occupational noise exposure, (A) characteristics of hearing loss, tinnitus, comorbidities, demographic characteristics and a history of work-related noise exposure and (B) differences among individuals employed in occupations with high and low risk of developing work-related noise-induced hearing loss (NIHL)...
September 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28880980/progressive-tinnitus-management-level-3-skills-education-a-5-year-clinical-retrospective
#18
Catherine M Edmonds, Cheri Ribbe, Emily J Thielman, James A Henry
Purpose: The primary purpose of this study was to determine whether progressive tinnitus management Level 3 skills education workshops conducted at the Bay Pines and Boston Veterans Affairs hospitals result in consistent use of the presented tinnitus management strategies by patients 1-5 years after completing the workshops. Method: In fiscal year (FY) 2015, the tinnitus workshop follow-up form was mailed to all veterans who completed the Level 3 workshops between FY 2010 and FY 2014...
September 18, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28878660/long-term-progression-of-sensorineural-hearing-loss-and-tinnitus-after-combined-intensity-modulated-radiation-therapy-and-cisplatin-based-chemotherapy-for-nasopharyngeal-carcinoma-a-case-report
#19
Ming S Lee, Sudha Penumala, Steven Sweet, Russell R De Luca, Ariel E Stearnes, Yamac Akgun
Sensorineural hearing loss (SNHL) is a common adverse effect for nasopharyngeal carcinoma (NPC) patients treated with chemoradiotherapy. We report a case of 12-year follow-up from a patient with stage IIB NPC, treated in 2004 with intensity-modulated radiotherapy and cisplatin-based chemotherapy. Pure-tone audiograms were conducted before treatment and at two other points in the 12-year period after treatment. Analysis of the patient's audiograms reveals that the development of high-frequency SNHL started after treatment and reached a plateau accompanied by tinnitus approximately 32 months after treatment conclusion...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28878303/typewriter-tinnitus-revisited-the-typical-symptoms-and-the-initial-response-to-carbamazepine-are-the-most-reliable-diagnostic-clues
#20
Woongsang Sunwoo, Yung Jin Jeon, Yun Jung Bae, Jeong Hun Jang, Ja-Won Koo, Jae-Jin Song
Although neurovascular compression of the cochlear nerve (NVC-C) presenting as typewriter tinnitus is a discrete disease category, verified diagnostic criteria are lacking. We sought to refine the diagnostic criteria for NVC-C by reference to a relatively large case series. The medical records of 22 NVC-C patients were retrospectively reviewed. Psychoacoustic characteristics, the results of diagnostic work-up (including audiovestibular neurophysiological tests and radiological evaluations), and the initial treatment response to carbamazepine were investigated...
September 6, 2017: Scientific Reports
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