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Intracranial hemorrhage

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https://www.readbyqxmd.com/read/29662916/intracranial-hemorrhage-and-autoimmune-thrombocytopenia-in-a-neonate-a-rare-unpredictable-event
#1
Andrea Becocci, Cristina Felice-Civitillo, Méryle Laurent, Françoise Boehlen, Roberta De Luca, Joel Fluss
Neonatal thrombocytopenia is a rare complication of maternal autoimmune thrombocytopenia, and no maternal predictors of its gravity and potential complications have been identified. Neonatal cerebral hemorrhage, a feared event in the setting of autoimmune thrombocytopenia, is fortunately uncommon, but it can occur in utero or in the perinatal period, with potentially serious consequences. The authors report the case of a boy born to a mother affected by autoimmune thrombocytopenia, who presented with severe thrombocytopenia at birth and developed intracranial hemorrhage despite mild maternal thrombocytopenia at delivery and a prompt preventive treatment of the newborn...
2018: Child Neurology Open
https://www.readbyqxmd.com/read/29660065/in-reply-angio-architectural-features-of-high-grade-intracranial-dural-arteriovenous-fistulas-correlation-with-aggressive-clinical-presentation-and-hemorrhagic-risk
#2
https://www.readbyqxmd.com/read/29660030/letter-angio-architectural-features-of-high-grade-intracranial-dural-arteriovenous-fistulas-correlation-with-aggressive-clinical-presentation-and-hemorrhagic-risk
#3
Sandra A Cornelissen, Leonard L L Yeo, Michael Söderman
No abstract text is available yet for this article.
April 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29658450/-influence-of-acute-pancreatitis-in-pregnancy-on-pregnancy-outcomes-and-neonates
#4
Shu-Juan Fan, Jun-Xi Xiang, Mi Xiao, Fang-Hui Wang, Xiao-Jie Lin, Xi-Hui Zhou, Ting Ai, Li Liu
OBJECTIVE: To study the influence of acute pancreatitis in pregnancy (APIP) on pregnancy outcomes and neonates. METHODS: A retrospective analysis was performed for 33 APIP patients and 31 neonates born alive. RESULTS: Of the 33 APIP patients, 26 (79%) developed APIP in the late pregnancy. Fourteen (45%) patients had hyperlipidemic APIP, 13 (42%) had biliary APIP, and 4 (13%) had other types of APIP. According to the severity, 22 (67%) were mild APIP, 5 (15%) were moderate APIP, and 6 were severe APIP...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29658447/-treatment-and-prognosis-of-pulmonary-hemorrhage-in-preterm-infants-during-2007-2016
#5
Wei-Wei Pan, Xiao-Mei Tong
OBJECTIVE: To study the treatment and prognosis of pulmonary hemorrhage in preterm infants. METHODS: A total of 106 preterm infants diagnosed with pulmonary hemorrhage, who were hospitalized in the neonatal ward of Peking University Third Hospital between 2007 and 2016, were enrolled. These patients were divided into 2007-2011 group (34 cases) and 2012-2016 group (72 cases) according to the time of hospitalization, divided into conventional-frequency ventilation group (43 cases) and high-frequency oscillatory ventilation (HFOV) group (63 cases) according to the respiratory support method used after the development of pulmonary hemorrhage, and divided into non-operation group (34 cases) and operation group (14 cases) according to whether PDA ligation was performed for the unclosed PDA before pulmonary hemorrhage...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29657898/slow-elevation-in-protein-c-activity-without-a-proc-mutation-in-a-neonate-with-intracranial-hemorrhage
#6
Erika Uehara, Hiro Nakao, Yusuke Tsumura, Hisaya Nakadate, Shoichiro Amari, Hideshi Fujinaga, Yoshiyuki Tsutsumi, Dongchon Kang, Shouichi Ohga, Akira Ishiguro
Severe protein C (PC) deficiency leads to purpura fulminans and stroke in newborns. However, the clinical impact of plasma PC activity on the development of neonatal cerebral disease remains elusive. We report a case of hemorrhagic stroke associated with neonatal asphyxia and severe PC deficiency. Plasma PC and protein S activity 7 days after birth was 12% and 43%, respectively. No PROC mutation was found. PC levels did not exceed 20% until 2 months of age, even in the absence of consumption coagulopathy or vitamin K deficiency...
April 2018: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29657592/design-and-baseline-characteristics-of-the-xarelto-post-authorization-safety-effectiveness-study-in-japanese-patients-with-atrial-fibrillation-xapass
#7
Satoshi Ogawa, Kazuo Minematsu, Takanori Ikeda, Takanari Kitazono, Jyoji Nakagawara, Susumu Miyamoto, Yuji Murakawa, Yohei Ohashi, Makiko Takeichi, Yutaka Okayama, Satoshi Yamanaka, Lyo Inuyama
Background: The phase III Japanese Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (J-ROCKET AF) showed that the rivaroxaban group had a lower event rate of intracranial bleeding than the warfarin group and that rivaroxaban was noninferior to warfarin for the principal safety outcome. However, safety and effectiveness data from unselected patients with AF in everyday clinical practice in Japan are lacking...
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29657060/characteristics-and-outcomes-of-ischemic-stroke-in-patients-with-known-atrial-fibrillation-or-atrial-fibrillation-diagnosed-after-stroke
#8
Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung
BACKGROUND: It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS. METHODS: Consecutive patients hospitalized between 2000 and 2012 for first-ever stroke along with atrial fibrillation, either diagnosed before or during the stroke hospitalization, were identified from a nationwide claims database in Taiwan...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29656986/eight-and-a-half-syndrome-a-combination-of-intracranial-capillary-telangiectasia-and-hematencephalon
#9
Wei Li, Deren Hou, Yanyao Deng, Yi Tian
Eight-and-a-half syndrome, a combination of one-and-a-half syndrome and ipsilateral facial palsy, was first described by Eggenberger in 1998. Intracranial capillary telangiectasia (ICT) is a rare type of latent cerebral vascular malformation characterized by a number of small, dilated, and thin-walled blood capillaries with normal brain tissues between them. Susceptibility weighted imaging is the recommended diagnostic method to detect ICT. Oommen once reported 1 case about pontine hemorrhage causing Fisher one-and-a-half syndrome with facial paralysis...
April 12, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29656278/anxiety-depression-and-adverse-clinical-outcomes-in-patients-with-atrial-fibrillation-starting-warfarin-cardiovascular-research-network-wave-study
#10
Christine Baumgartner, Dongjie Fan, Margaret C Fang, Daniel E Singer, Daniel M Witt, John R Schmelzer, Marc S Williams, Jerry H Gurwitz, Sue Hee Sung, Alan S Go
BACKGROUND: Anxiety and depression are associated with worse outcomes in several cardiovascular conditions, but it is unclear whether they affect outcomes in atrial fibrillation (AF). In a large diverse population of adults with AF, we evaluated the association of diagnosed anxiety and/or depression with stroke and bleeding outcomes. METHODS AND RESULTS: The Cardiovascular Research Network WAVE (Community-Based Control and Persistence of Warfarin Therapy and Associated Rates and Predictors of Adverse Clinical Events in Atrial Fibrillation and Venous Thromboembolism) Study included adults with AF newly starting warfarin between 2004 and 2007 within 5 health delivery systems in the United States...
April 14, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29656154/acute-recanalization-of-a-partially-thrombosed-large-intracranial-aneurysm
#11
E Atallah, E Valle-Giler, T Elarjani, N Chalouhi, S Tjoumakaris, R H Rosenwasser, N Herial, M R Gooch, H Zarzour, P Jabbour
BACKGROUND: Thrombosed large intracranial aneurysms(TLIAs) are not continuously contemplated as stable lesions. Completely occluded large IAs' spontaneous recanalization has been previously described. CASE DESCRIPTION: We report the case of a middle-aged patient presenting with agitation, acute headache, visual field defects and left hemiparesis. A large thrombosed Posterior Communicating (PCom) artery aneurysm was identified with an infarct at the same arterial territory on neuroimaging studies...
April 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29651951/inflammatory-events-following-subarachnoid-hemorrhage-sah
#12
U C Schneider, R Xu, P Vajkoczy
Acute SAH from a ruptured intracranial aneurysm contributes for 30% of all hemorrhagic strokes. The bleeding itself occurs in the subarachnoid space. Nevertheless, injury to the brain parenchyma occurs as a consequence of the bleeding, directly, via several well-defined mechanisms and pathways, but also indirectly, or secondarily. This secondary brain injury following SAH has a variety of causes and possible mechanisms. Amongst others, inflammatory events have been shown to occur in parallel to, to contribute to, or even to initiate programmed cell death (PCD) within the central nervous system (CNS) in human and animal studies alike...
April 11, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29650593/human-neural-stem-cell-extracellular-vesicles-improve-recovery-in-a-porcine-model-of-ischemic-stroke
#13
Robin L Webb, Erin E Kaiser, Brian J Jurgielewicz, Samantha Spellicy, Shelley L Scoville, Tyler A Thompson, Raymond L Swetenburg, David C Hess, Franklin D West, Steven L Stice
BACKGROUND AND PURPOSE: Recent work from our group suggests that human neural stem cell-derived extracellular vesicle (NSC EV) treatment improves both tissue and sensorimotor function in a preclinical thromboembolic mouse model of stroke. In this study, NSC EVs were evaluated in a pig ischemic stroke model, where clinically relevant end points were used to assess recovery in a more translational large animal model. METHODS: Ischemic stroke was induced by permanent middle cerebral artery occlusion (MCAO), and either NSC EV or PBS treatment was administered intravenously at 2, 14, and 24 hours post-MCAO...
April 12, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29648985/feasibility-of-telemetric-intracranial-pressure-monitoring-in-the-neuro-intensive-care-unit
#14
Alexander Lilja-Cyron, Jesper Kelsen, Morten Andresen, Kåre Fugleholm, Marianne Juhler
Intracranial pressure (ICP) monitoring is crucial in the management of acute neurosurgical conditions such as traumatic brain injury (TBI). However, pathological ICP may persist beyond the admission to the neuro intensive care unit (NICU). We investigated the feasibility of telemetric ICP monitoring in the NICU, as this technology provides the possibility of long-term ICP assessment beyond NICU discharge. In this prospective investigation, we implanted telemetric ICP sensors (Raumedic Neurovent-P-tel) instead of conventional, cabled ICP sensors in patients undergoing decompressive craniectomy...
March 16, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29644277/isolated-orbital-roof-blow-in-fracture
#15
Kaitlyn M Rountree, John J Blase
We report a rare case of a right orbital roof blow-in fracture in a 40-year-old male with concomitant basal skull fracture and intracranial hemorrhage after a fall backward. Trauma, neurosurgery, ophthalmology, and maxillofacial surgery consultations were obtained. Conservative, non-surgical management was recommended for all injuries, and outpatient follow up for orbital fracture with no surgery offered.
December 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29629522/the-influence-of-sex-in-stroke-thrombolysis-a-systematic-review-and-meta-analysis
#16
REVIEW
Mingsu Liu, Guangqin Li, Jie Tang, Yan Liao, Lin Li, Yang Zheng, Tongli Guo, Xin Kang, Maoting Yuan
BACKGROUND AND PURPOSE: There is increasing recognition of the importance of stroke in females to both clinical and public health. The natural course of stroke is worse in females than in males, but the evidence regarding sex disparities in the responses to thrombolysis in stroke patents is still controversial. We compared outcomes after thrombolysis treatment between females and males. METHODS: Clinical trials reported in the Embase, PubMed, and Cochrane Library electronic databases up to March 13, 2017 were included in this analysis...
April 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29628946/a-prospective-multicenter-trial-of-the-transform-occlusion-balloon-catheter-trial-design-and-results
#17
M Asif Taqi, Syed A Quadri, Ajit S Puri, Brian F Fitzsimmons, Jianhua Nancy Jin, Ansaar T Rai, Curtis A Given, Javier Masso, Ciaran J Powers, Joey D English, Osama O Zaidat
Background and Purpose: Adjunctive treatments like balloon-assisted coil embolization (BACE) and stent-assisted coil embolization play a major role in the treatment of wide-neck and large intracranial aneurysms. The TransForm™ Occlusion Balloon Catheter (TOBC) registry is intended to evaluate the safety, efficacy, and efficiency of BACE using the TOBC. Method and Study Design: The TOBC registry is a prospective multicenter registry trial. Seven sites in the USA and 1 site in Spain participated and enrolled 81 patients...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628945/balloon-assisted-cannulation-for-difficult-anterior-cerebral-artery-access
#18
Varun Naragum, Mohamad AbdalKader, Thanh N Nguyen, Alexander Norbash
The anterior communicating artery is a common location for intracranial aneurysms. Compared to surgical clipping, endovascular coiling has been shown to improve outcomes for patients with ruptured aneurysms and we have seen a paradigm shift favoring this technique for treating aneurysms. Access to the anterior cerebral artery can be challenging, especially in patients with tortuous anatomy or subarachnoid hemorrhage or in patients presenting with vasospasm. We present a technique for cannulating the anterior cerebral artery using a balloon inflated in the proximal middle cerebral artery as a rebound surface...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628944/is-the-efficacy-of-endovascular-treatment-for-acute-ischemic-stroke-sex-related
#19
Andreia Carvalho, André Cunha, Tiago Gregório, Ludovina Paredes, Henrique Costa, Miguel Veloso, Sérgio Castro, Manuel Ribeiro, Pedro Jorge Gonçalves Barros
Background: Several reports refer to differences in stroke between females and males, namely in incidence and clinical outcome, but also in response to treatments. Driven by a recent analysis of the MR CLEAN trial, which showed a higher benefit from acute stroke endovascular treatment (EVT) in males, we intended to determine if clinical outcomes after EVT differ between sexes, in a real-world setting. Methods: We analyzed 145 consecutive patients submitted to EVT for anterior circulation large-vessel occlusion, between January 2015 and September 2016, and compared the outcomes between sexes...
February 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29628941/early-outcome-after-intracranial-hemorrhage-related-to-non-vitamin-k-oral-anticoagulants
#20
Senta Frol, Janja Pretnar Oblak
Background: Intracranial hemorrhage (ICH) is a serious, life-threatening, but fortunately rare complication of non-vitamin K oral anticoagulant (NOAC) therapy. There are limited data on NOAC-related ICH prognosis. Methods: All consecutive patients admitted to a single center due to acute NOAC-related ICH from September 2012 until the beginning of 2017 were included. Risk factors, type of NOAC, and location of ICH were evaluated. Risk for ischemic and bleeding events and clinical status upon admission and at discharge were evaluated using standard scales...
February 2018: Interventional Neurology
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