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https://www.readbyqxmd.com/read/28344469/acute-toxicity-profiling-of-the-ethyl-acetate-fraction-of-swietenia-macrophylla-seeds-and-in-vitro-neuroprotection-studies
#1
Mustak Sayyad, Ning Tiang, Yatinesh Kumari, Bey Hing Goh, Yogini Jaiswal, Rozita Rosli, Leonard Williams, Mohd Farooq Shaikh
Swietenia macrophylla (SM) is a medicinally important plant found in tropical and subtropical regions of the world. The ethyl acetate fraction of the seeds of S. macrophylla (SMEAF) is reported to exhibit potent anticancer, antitumor, anti-inflammatory and antifeedant activities. Till date, there have been no studies reported on the acute oral toxicity profile of the ethyl acetate fraction of the seeds of SM. The objective of the present study was to determine the acute toxicity of SMEAF and evaluate the in-vitro neuroprotective activity of SMEAF using primary neuronal cell cultures...
February 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28341010/history-and-development-of-ophthalmology-in-taiwan
#2
REVIEW
Yu-Chih Hou, Gale A Oren, Muh-Shy Chen, Fung-Rong Hu
Western medicine was first introduced to Taiwan by medical missionaries in the mid-19(th) century. Modernization of medicine was systematically transplanted to Taiwan in the Japanese colonial period, and ophthalmology was established third among hospital departments, following internal medicine and surgery. Dr Hidetaka Yamaguchi, an ophthalmologist, was the first head of the Taihoku Hospital, later known as National Taiwan University Hospital (NTUH; Taipei, Taiwan). Ophthalmologists during the colonial period conducted studies on tropical and infectious eye diseases...
December 2016: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28338625/-r-aloesaponol-iii-8-methyl-ether-from-eremurus-persicus-a-novel-compound-against-leishmaniosis
#3
Daniela Rossi, Karzan Mahmood Ahmed, Raffaella Gaggeri, Serena Della Volpe, Lauretta Maggi, Giuseppe Mazzeo, Giovanna Longhi, Sergio Abbate, Federica Corana, Emanuela Martino, Marisa Machado, Raquel Varandas, Maria do Céu Sousa, Simona Collina
Leishmaniosis is a neglected tropical disease which affects several millions of people worldwide. The current drug therapies are expensive and often lack efficacy, mainly due to the development of parasite resistance. Hence, there is an urgent need for new drugs effective against Leishmania infections. As a part of our ongoing study on the phytochemical characterization and biological investigation of plants used in the traditional medicine of western and central Asia, in the present study, we focused on Eremurus persicus root extract in order to evaluate its potential in the treatment of leishmaniosis...
March 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28334826/military-officers-tropical-medicine-and-racial-thought-in-the-formation-of-the-west-india-regiments-1793-1802
#4
Michael Joseph
No abstract text is available yet for this article.
March 9, 2017: Journal of the History of Medicine and Allied Sciences
https://www.readbyqxmd.com/read/28333074/assessment-of-the-anti-hyperglycaemic-anti-inflammatory-and-antioxidant-activities-of-the-methanol-extract-of-moringa-oleifera-in-diabetes-induced-nephrotoxic-male-wistar-rats
#5
Elizabeth I Omodanisi, Yapo G Aboua, Oluwafemi O Oguntibeju
Diabetes mellitus is an endocrine disease of multiple aetiologies in insulin secretion. A deficiency in insulin results in hyperglycemia with metabolic disturbances of biomolecules. Moringa oleifera (MO) is endemic in the tropics with a variety of ethnomedicinal importance. The leaf of this plant has been reported to possess antioxidant and medicinal properties that may be helpful in the treatment and management of diabetes and its associated complications. Diabetes was induced intraperitoneally in rats by a single dose of streptozotocin (55 mg/kg) and treated with methanolic extract of Moringa oleifera (250 mg/kg b...
March 23, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28330275/phytochemicals-of-moringa-oleifera-a-review-of-their-nutritional-therapeutic-and-industrial-significance
#6
REVIEW
Ramesh Kumar Saini, Iyyakkannu Sivanesan, Young-Soo Keum
Moringa oleifera Lam., also known as the 'drumstick tree,' is recognized as a vibrant and affordable source of phytochemicals, having potential applications in medicines, functional food preparations, water purification, and biodiesel production. The multiple biological activities including antiproliferation, hepatoprotective, anti-inflammatory, antinociceptive, antiatherosclerotic, oxidative DNA damage protective, antiperoxidative, cardioprotective, as well as folk medicinal uses of M. oleifera (MO) are attributed to the presence of functional bioactive compounds, such as phenolic acids, flavonoids, alkaloids, phytosterols, natural sugars, vitamins, minerals, and organic acids...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28290949/dod-supported-overseas-training-rotations-in-tropical-medicine-and-global-health-2000-2015
#7
James D Mancuso, Patrick W Hickey, Rodney L Coldren, Amy K Korman, Lisa W Keep, Robert F DeFraites, Maria Smith, Luke J Mancuso, Jose L Sanchez
In 1999, the Department of Defense developed a tropical medicine training program (TMTP) to train military physicians, medical students, and scientists in performing surveillance activities in an overseas environment. This review describes the competencies, educational approach, program participants, institutional collaborations, and process outcomes of the TMTP from 2000 to 2015. TMTP-sponsored rotations addressed a wide variety of interdisciplinary competencies, many of which have military-unique applications...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28284793/toxic-pyrrolizidine-alkaloids-in-herbal-medicines-commonly-used-in-ghana
#8
Emmanuel Letsyo, Gerold Jerz, Peter Winterhalter, Till Beuerle
ETHNOPHARMACOLOGICAL RELEVANCE: Herbal medicines have been used for centuries for the management and treatment of various ailments due to the belief that they pose only little or no health risk and side effects, and also, in part, due to their availability, affordability and/or self-supply. However, the increasing information over the recent years on the occurrence of pyrrolizidine alkaloids (PAs) in honey, herbal food and tea products has raised concerns about the safety of herbal medicines with respect to contamination...
March 8, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28279997/association-between-highly-active-antiretroviral-therapy-and-selected-cardiovascular-disease-risk-factors-in-sub-saharan-africa-a-systematic-review-and-meta-analysis-protocol
#9
Christian Akem Dimala, Hannah Blencowe
INTRODUCTION: The increasing highly active antiretroviral therapy (HAART) coverage in sub-Saharan Africa (SSA) has been associated with increasing cardiovascular disease (CVD) incidence. However, the epidemiology of the association between HAART and CVD risk factors in SSA is sparse. We aim to assess the extent to which HAART is associated with selected cardiovascular risk factors (hypertension, diabetes, dyslipidaemia and metabolic syndrome) in SSA. METHODS AND ANALYSIS: This will be a systematic review and meta-analysis of published studies on the association between HAART and CVD risk factors retrieved from Medline, Embase, Popline, Africa-Wide Information, African Index Medicus and the Cochrane library databases...
March 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28279633/kikuchi-fujimoto-disease-a-rare-cause-of-lymphadenopathy-in-africa-description-of-the-first-case-in-senegal-and-review-of-the-literature
#10
C-A Lame, B Loum, A-K Fall, J Cucherousset, A-R Ndiaye
INTRODUCTION: Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is a benign disease most commonly affecting adult females. It generally presents in the form of febrile cervical lymphadenopathy. This diagnosis must be considered in the setting of tropical medicine, dominated by a high prevalence of tuberculous lymphadenitis and haematological malignancies. CASE REPORT: The authors report the case of a 33-year-old Senegalese woman who presented with subacute cervical lymphadenopathy associated with fever and laboratory signs of inflammation...
March 6, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28271980/mosquito-borne-diseases-and-omics-salivary-gland-proteome-of-the-female-aedes-aegypti-mosquito
#11
Rakhi Dhawan, Manish Kumar, Ajeet Kumar Mohanty, Gourav Dey, Jayshree Advani, T S Keshava Prasad, Ashwani Kumar
The female Aedes aegypti mosquito is an important vector for several tropical and subtropical diseases such as dengue, chikungunya, and Zika and yellow fever. The disease viruses infect the mosquito and subsequently spread to the salivary glands after which the viruses can be transmitted to humans with probing or feeding by the mosquito. Omics systems sciences offer the opportunity to characterize vectors and can inform disease surveillance, vector control and development of innovative diagnostics, personalized medicines, vaccines, and insecticide targets...
January 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28266011/traditional-uses-phytochemistry-and-pharmacology-of-the-medicinal-species-of-the-genus-cordia-boraginaceae
#12
REVIEW
Manisha J Oza, Yogesh A Kulkarni
OBJECTIVES: Cordia (family Boraginaceae) is a genus of deciduous flowering trees or shrubs comprising more than 300 species distributed widely in the tropical regions. The aim of this review was to provide exhaustive scientific information on traditional uses, phytochemistry and pharmacological activities of the 36 important species with medicinal value from the genus Cordia, to divulge prospects for further research on its therapeutic potential. KEY FINDINGS: Leaves, fruit, bark and seed of a majority of the species were found to possess abundant ethnomedicinal value, but leaves were found to be used most frequently to treat many ailments such as respiratory disorders, stomach pain, wound, inflammation, myalgia, cough, dysentery and diarrhoea...
March 7, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28252174/molecular-marker-based-genetic-diversity-analysis-of-scantly-studied-brazilian-accessions-of-a-medicinal-plant-morinda-citrifolia-l-noni
#13
P N Bordallo, A M R Monteiro, J A Sousa, F A S Aragão
Morinda citrifolia L., commonly known as noni, has been used for the treatment of various diseases for over two centuries. It was introduced and widely disseminated in Brazil because of its high market value and ease of adaptation to the soil and climatic conditions of the country. The aim of this study was to estimate the genetic variability of noni accessions from the collection of Embrapa Agroindústria Tropical in Brazil. We evaluated 36 plants of the 13 accessions of noni from the germplasm collection of M...
February 23, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28249253/selective-anti-proliferative-activities-of-carica-papaya-leaf-juice-extracts-against-prostate-cancer
#14
Saurabh Pandey, Carina Walpole, Peter J Cabot, Paul N Shaw, Jyotsna Batra, Amitha K Hewavitharana
BACKGROUND: Prostate cancer (PCa) is the leading cause of cancer related deaths in men. Carica papaya is a popular tropical plant that has been traditionally used for its nutritional and medicinal properties. METHODS: We investigated the anti-proliferative responses of papaya leaf juice (LJP) and its various extracts ("biological"- in vitro digested, "physical"- size exclusion, and "chemical"-solvent extraction) on a range of cell lines representing benign hyperplasia, tumorigenic and normal cells of prostate origin...
February 26, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28248871/partial-thickness-burn-wounds-healing-by-topical-treatment-a-randomized-controlled-comparison-between-silver-sulfadiazine-and-centiderm
#15
RANDOMIZED CONTROLLED TRIAL
Amin Saeidinia, Faeze Keihanian, Ardalan Pasdaran Lashkari, Hossein Ghavvami Lahiji, Mohammadreza Mobayyen, Abtin Heidarzade, Javad Golchai
BACKGROUND: Burns are common event and associated with a high incidence of death, disability, and high costs. Centella asiatica (L.) is a medicinal herb, commonly growing in humid areas in several tropical countries that improve wound healing. On the basis of previous studies, we compared the efficacy of Centiderm versus silver sulfadiazine (SSD) in partial thickness burning patients. METHODS: Study population comprised burn victims referred to Velayat Burning Hospital at Rasht, Iran...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28247996/tropical-medicine-international-health
#16
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28243901/the-genus-carissa-an-ethnopharmacological-phytochemical-and-pharmacological-review
#17
REVIEW
Joseph Sakah Kaunda, Ying-Jun Zhang
Carissa L. is a genus of the family Apocynaceae, with about 36 species as evergreen shrubs or small trees native to tropical and subtropical regions of Africa, Asia and Oceania. Most of Carissa plants have been employed and utilized in traditional medicine for various ailments, such as headache, chest complains, rheumatism, oedema, gonorrhoea, syphilis, rabies. So far, only nine Carissa species have been phytochemically studied, which led to the identification of 123 compounds including terpenes, flavonoids, lignans, sterols, simple phenolic compounds, fatty acids and esters, and so on...
February 27, 2017: Natural Products and Bioprospecting
https://www.readbyqxmd.com/read/28243398/serum-midkine-and-osteopontin-levels-as-diagnostic-biomarkers-of-hepatocellular-carcinoma
#18
Hossam Hodeib, Ola ELshora, Amal Selim, Nesreen Mohammed Sabry, Heba Mohamed El-Ashry
INTRODUCTION: Hepatocellular Carcinoma (HCC) is a primary tumor of the liver; it is one of the most common cancers worldwide. Osteopontin (OPN) is a phosphorylated glycoprotein which is implicated in enhancing invasive and metastatic progression of many tumors. Midkine (MDK) is a 13-kDa small heparin-binding growth factor which plays a significant role in carcinogenesis related activities. The aim of this study was to assess the efficacy of serum Midkine and Osteopontin levels as diagnostic biomarkers of Hepatocellular Carcinoma...
January 2017: Electronic Physician
https://www.readbyqxmd.com/read/28217577/physicians-of-colonial-india-1757-1900
#19
REVIEW
Anu Saini
The period of British rule from 1757 to 1900 is marked by major sociopolitical changes and scientific breakthroughs that impacted medical systems, institutions, and practitioners in India. In addition, historians have debated whether the colonial regime used Western medicine as a tool to expand and legitimize its rule. This paper reviews the secondary literature on this subject with emphasis on the individual physicians. During this period, the practice of "Doctory" or Western medicine gained momentum in India, buoyed with the support of the British as well as Western-educated Indians...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28216948/averrhoa-bilimbi-linn-a-review-of-its-ethnomedicinal-uses-phytochemistry-and-pharmacology
#20
REVIEW
Alhassan Muhammad Alhassan, Qamar Uddin Ahmed
Averrhoa bilimbi Linn. is principally cultivated for medicinal purposes in many tropical and subtropical countries of the world. Literature survey about this plant shows that A. bilimbi is mainly used as a folk medicine in the treatment of diabetes mellitus, hypertension, and as an antimicrobial agent. The prime objective of this review is to accumulate and organize literature based on traditional claims and correlate those with current findings on the use of A. bilimbi in the management of different ailments...
October 2016: Journal of Pharmacy & Bioallied Sciences
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