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https://www.readbyqxmd.com/read/28072853/terrestrial-macrofungal-diversity-from-the-tropical-dry-evergreen-biome-of-southern-india-and-its-potential-role-in-aerobiology
#1
Hema Priyamvada, M Akila, Raj Kamal Singh, R Ravikrishna, R S Verma, Ligy Philip, R R Marathe, L K Sahu, K P Sudheer, S S Gunthe
Macrofungi have long been investigated for various scientific purposes including their food and medicinal characteristics. Their role in aerobiology as a fraction of the primary biological aerosol particles (PBAPs), however, has been poorly studied. In this study, we present a source of macrofungi with two different but interdependent objectives: (i) to characterize the macrofungi from a tropical dry evergreen biome in southern India using advanced molecular techniques to enrich the database from this region, and (ii) to assess whether identified species of macrofungi are a potential source of atmospheric PBAPs...
2017: PloS One
https://www.readbyqxmd.com/read/28068904/long-term-kinetics-of-zika-virus-rna-and-antibodies-in-body-fluids-of-a-vasectomized-traveller-returning-from-martinique-a-case-report
#2
Guenter Froeschl, Kristina Huber, Frank von Sonnenburg, Hans-Dieter Nothdurft, Gisela Bretzel, Michael Hoelscher, Lothar Zoeller, Matthias Trottmann, Francisco Pan-Montojo, Gerhard Dobler, Silke Woelfel
BACKGROUND: The magnitude of the current Zika virus (ZIKV) epidemic has led to a declaration of a Public Health Emergency of International Concern by the WHO. Findings of viable viral particles in semen for several weeks are corroborating reports of sexual transmission of ZIKV. Serious consequences of a positive diagnostic result particularly in the pregnant patient are calling for precise diagnostic tools also at later time points after infection. Currently, recommendations suggest a diagnostic period of direct viral detection of 5 to 7 days after onset of symptoms in serum or plasma, and up to 3 weeks in urine samples...
January 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28043557/antimycobacterial-potency-and-cytotoxicity-study-of-three-medicinal-plants
#3
Patrick Valere Tsouh Fokou, Regina Appiah-Opong, Dorothy Yeboah-Manu, Abena Adomah Kissi-Twum, Lauve Rachel Tchokouaha Yamthe, Aristide Laurel Mokale Kognou, Phyllis Addo, Fabrice Fekam Boyom, Alexander Kwadwo Nyarko
OBJECTIVE/BACKGROUND: Mycobacterial infections including tuberculosis, leprosy, and buruli ulcer are among the most prevalent, debilitating, and deadly tropical diseases, especially in Sub-Saharan Africa. The development of drug resistance to the currently available drugs and the poor compliance emphasize the need for new chemotherapeutic agents. This study was designed to evaluate the in vitro activity of Cleistopholis patens, Annona reticulata, and Greenwayodendron suaveolens against Mycobacterium smegmatis...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043556/antimycobacterial-ingredients-from-plants-used-in-traditional-medicine-to-treat-buruli-ulcer
#4
Patrick Valere Tsouh Fokou, Abena Adomah Kissi-Twum, Dorothy Yeboah-Manu, Regina Appiah-Opong, Phyllis Addo, Lauve Rachel Tchokouaha Yamthe, Alvine Ngoutane Mfopa, Fabrice Fekam Boyom, Alexander Kwadwo Nyarko
AIM AND OBJECTIVES: Buruli ulcer (BU) is a neglected tropical disease caused by a mycobacteria, Mycobacterium ulcerans. The WHO recommended Rifampicin-Streptomycin combination side effects and poor compliance, leaves rural populations with no choice than to patronise indigenous remedies. This study is aimed at validating medicinal plants used in traditional medicine to treat BU by investigating the in vitro efficacy and safety as well as their composition in active molecules. METHODS: A short report-based survey was used to identify medicinal plants used traditionally for BU treatment...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043490/antimycobacterial-activity-of-medicinal-plants-against-the-causative-agent-of-buruli-ulcer-mycobacterium-ulcerans
#5
R Keumoe, M S Nguembou, F P V Tsouh, D V F Donkeng, D Dize, Y L R Tchokouaha, M C D Jiatsa, F R D Youmsi, B Ngameni, B F Fekam
OBJECTIVE/BACKGROUND: Buruli ulcer, known as necrotizing skin disease caused by Mycobacterium ulcerans, has emerged as the most prevalent mycobacteriosis after leprosy and tuberculosis. Accordingly, it has been classified by the World Health Organization as a neglected disease with high significance in tropical areas, including Cameroon. So far, the control of the disease relies mainly on the rifampin-streptomycin combination. Despite its efficiency, it has shown considerable issues, including availability and side effects...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043098/tropical-medicine-international-health
#6
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28041556/polyphenols-from-allanblackia-floribunda-seeds-identification-quantification-and-antioxidant-activity
#7
Grace A Akpanika, Ana Winters, Thomas Wilson, Gloria A Ayoola, Aderonke A Adepoju-Bello, Barbara Hauck
Oil rich seeds of Allanblackia floribunda, a tree from tropical Africa, have traditionally been used in food preparation. Furthermore, the therapeutic properties of various parts of this tree have long been exploited in traditional medicine. As both food and pharmaceutical industries show growing interest in tropical tree crops, this study aimed to investigate whether A. floribunda seeds could also be used as a source of potentially bioactive compounds. The polyphenol profile revealed six predominant compounds which were identified by HPLC-PDA-ESI/MS(n) as the biflavonoids morelloflavone, Gb-2a and volkensiflavone and their respective glucosides...
May 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28032738/-diagnosis-and-treatment-of-imported-eosinophilia-in-travellers-and-immigrants-recommendations-of-the-spanish-society-of-tropical-medicine-and-international-health-semtsi
#8
J Salas-Coronas, G Ramírez-Olivencia, J L Pérez-Arellano, M Belhassen-García, C Carranza-Rodríguez, M García-Rodríguez, J Villar-Garcia, B Treviño-Maruri, N Serre-Delcor, R López-Vélez, F Norman, J Gómez-Junyent, M J Soriano-Pérez, G Rojo-Marcos, E Rodríguez de Las Parras, M M Lago-Núñez, A Muro, J Muñoz
According to published data, prevalence of imported eosinophilia among travellers and immigrants is set between 8% and 28.5%. Etiological diagnosis is often troublesome, and depending on the depth of the study and on the population analyzed, a parasitic cause is identified in 17% to 75.9% of the individuals. Among the difficulties encountered to compare studies are the heterogeneity of the studied populations, the type of data collection (prospective/retrospective) and different diagnostic protocols. In this document the recommendations of the expert group of the Spanish Society of Tropical Medicine and International Health (SEMTSI) for the diagnosis and treatment of imported eosinophilia are detailed...
December 29, 2016: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28031600/medical-curriculum-and-pharmacology-an-appraisal
#9
P S R K Haranath
Pharmacology was introduced with Western Medical Education in India in 1900s. RN Chopra was the first Professor of Pharmacology along with patient care in School of Tropical Medicine Calcutta. Now Pharmacologists do not have clinical care nor give laboratory services to hospitals. Medical Education advanced in the West in 1960s with more emphasis on Integrated Teaching and Student Self-study and less on didactic lectures. System Based Learning and Problem Based Learning reduced importance of individual subjects...
October 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28031196/nanotized-curcumin-and-miltefosine-a-potential-combination-for-the-treatment-of-experimental-visceral-leishmaniasis
#10
Brajendra Tiwari, Richa Pahuja, Pradeep Kumar, Srikanth Kumar Rath, Kailash Chand Gupta, Neena Goyal
Leishmaniasis chemotherapy remains very challenging due to high cost of the drug and its associated toxicity and drug resistance which develops over a period of time. Now-a-days combination therapies (CT) are in use for many diseases like cancer and malaria being more effective and affordable than monotherapy. CT is believed to represent a new explorable strategy for leishmaniasis, a neglected tropical disease caused by obligate intracellular parasite Leishmania In the present work, we have adopted a rational approach, to investigate the effect of combination of traditional Indian medicine (Ayurveda), a natural product curcumin and miltefosine, the only oral drug for visceral leishmaniasis (VL) using Leishmania (Leishmania) donovani/hamster model...
December 28, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28028039/draft-genome-sequence-of-bitter-gourd-momordica-charantia-a-vegetable-and-medicinal-plant-in-tropical-and-subtropical-regions
#11
Naoya Urasaki, Hiroki Takagi, Satoshi Natsume, Aiko Uemura, Naoki Taniai, Norimichi Miyagi, Mai Fukushima, Shouta Suzuki, Kazuhiko Tarora, Moritoshi Tamaki, Moriaki Sakamoto, Ryohei Terauchi, Hideo Matsumura
Bitter gourd (Momordica charantia) is an important vegetable and medicinal plant in tropical and subtropical regions globally. In this study, the draft genome sequence of a monoecious bitter gourd inbred line, OHB3-1, was analyzed. Through Illumina sequencing and de novo assembly, scaffolds of 285.5 Mb in length were generated, corresponding to ∼84% of the estimated genome size of bitter gourd (339 Mb). In this draft genome sequence, 45,859 protein-coding gene loci were identified, and transposable elements accounted for 15...
December 27, 2016: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
https://www.readbyqxmd.com/read/28011170/antiprotozoal-drug-nitazoxanide-enhances-parasitemia-tissue-lesions-and-mortality-caused-by-trypanosoma-cruzi-in-murine-model
#12
Juan Salvador Valle-Reyes, Valery Melnikov, Oxana Dobrovinskaya, Alejandrina Rodriguez-Hernández, Cristina Wookee-Zea, Víctor Pimientel-Rodrigez, Gabriela Rueda-Valdovinos, Iván Delgado-Enciso, Uriel A López-Lemus, Francisco Espinoza-Gómez
Chagas' disease is caused by unicellular parasite Trypanosoma cruzi (T. cruzi). It is endemic throughout Latin America, but nowadays has become a global challenge due to tourism and migration. Non-treated infection may result in health-threatening complications and lead to death. Current medications for this infection are nifurtimox (NFT) and benznidazol. Both drugs may cause side effects and are ineffective in the chronic phase. Therefore, new antichagasic compounds are urgently required. Nitazoxanide (NTZ) is a broad spectrum antiparasitic drug, proposed recently as a potential candidate to be added to the list of essential medicines for integrated neglected tropical disease control and elimination...
December 21, 2016: Experimental Parasitology
https://www.readbyqxmd.com/read/28004603/asiatic-acid-attenuates-pre-neoplastic-lesions-oxidative-stress-biotransforming-enzymes-and-histopathological-alterations-in-1-2-dimethylhydrazine-induced-experimental-rat-colon-carcinogenesis
#13
Aktarul Islam Siddique, Vijay Mani, Sivaranjani Arivalagan, Nisha Susan Thomas, Namasivayam Nalini
Asiatic acid (AA), a pentacyclic triterpenoid derived from the tropical medicinal plant Centella asiatica is known to exhibit numerous pharmacological properties. We hypothesized that AA will have chemopreventive potential against 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis in male Wistar rats. Rats were arbitrarily divided into six groups. Group I rats were processed as control. Group II rats received AA (8 mg/kg b.w., p.o.) and groups III-VI rats received subcutaneous injections of DMH (20 mg/kg b...
December 22, 2016: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/27999405/moringa-oleifera-seeds-and-oil-characteristics-and-uses-for-human-health
#14
REVIEW
Alessandro Leone, Alberto Spada, Alberto Battezzati, Alberto Schiraldi, Junior Aristil, Simona Bertoli
Moringa oleifera seeds are a promising resource for food and non-food applications, due to their content of monounsaturated fatty acids with a high monounsaturated/saturated fatty acids (MUFA/SFA) ratio, sterols and tocopherols, as well as proteins rich in sulfated amino acids. The rapid growth of Moringa trees in subtropical and tropical areas, even under conditions of prolonged drought, makes this plant a reliable resource to enhance the nutritional status of local populations and, if rationalized cultivation practices are exploited, their economy, given that a biodiesel fuel could be produced from a source not in competition with human food crops...
December 20, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27998330/medical-science-meets-development-aid-transfer-and-adaptation-of-west-german-microbiology-to-togo-1960-1980
#15
Carola Rensch, Walter Bruchhausen
After losing the importance it had held around 1900 both as a colonial power and in the field of tropical medicine, Germany searched for a new place in international health care during decolonisation. Under the aegis of early government 'development aid', which started in 1956, medical academics from West German universities became involved in several Asian, African and South American countries. The example selected for closer study is the support for the national hygiene institute in Togo, a former German 'model colony' and now a stout ally of the West...
January 2017: Medical History
https://www.readbyqxmd.com/read/27991959/local-anesthetic-activity-from-extracts-fractions-and-pure-compounds-from-the-roots-of-ottonia-anisum-spreng-piperaceae
#16
Kelvin S E López, André M Marques, Davyson DE L Moreira, Leosvaldo S Velozo, Roberto T Sudo, Gisele Zapata-Sudo, Elsie F Guimarães, Maria Auxiliadora C Kaplan
Piperaceae species can be found worldwide in tropical and subtropical areas and many of them have been used for centuries in traditional folk medicine and in culinary. In Brazil, species of Piperaceae are commonly used in some communities as local anesthetic and analgesic. Countrified communities have known some species of the genus Ottonia as "anestesia" and it is a common habit of chewing leaves and roots of Ottonia species to relief toothache. The purpose of this study is to report our findings on new molecules entities obtained from the roots of Ottonia anisum Spreng, in which local anesthetic activity (sensory blockage) is demonstrated for the first time in vivo guinea pig model...
October 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27988402/traditional-uses-phytochemistry-and-pharmacology-of-wild-banana-musa-acuminata-colla-a-review
#17
REVIEW
Nimisha Sarah Mathew, Pradeep Singh Negi
ETHNOPHARMACOLOGICAL RELEVANCE: Musa acuminata, the wild species of banana is a plant of the tropical and subtropical regions. Over the past few decades, the health benefits of M. acuminata have received much attention. All parts of the plant including fruits, peel, pseudostem, corm, flowers, leaves, sap and roots have found their use in the treatment of many diseases in traditional medicine. Literature review have indicated use of M. acuminata in the treatment of various diseases such as fever, cough, bronchitis, dysentery, allergic infections, sexually transmitted infections, and some of the non-communicable diseases...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27982292/2-nd-brazilian-consensus-on-chagas-disease-2015
#18
João Carlos Pinto Dias, Alberto Novaes Ramos, Eliane Dias Gontijo, Alejandro Luquetti, Maria Aparecida Shikanai-Yasuda, José Rodrigues Coura, Rosália Morais Torres, José Renan da Cunha Melo, Eros Antonio de Almeida, Wilson de Oliveira, Antônio Carlos Silveira, Joffre Marcondes de Rezende, Fabiane Scalabrini Pinto, Antonio Walter Ferreira, Anis Rassi, Abílio Augusto Fragata, Andréa Silvestre de Sousa, Dalmo Correia, Ana Maria Jansen, Glaucia Manzan Queiroz Andrade, Constança Felícia De Paoli de Carvalho Britto, Ana Yecê das Neves Pinto, Anis Rassi, Dayse Elisabeth Campos, Fernando Abad-Franch, Silvana Eloi Santos, Egler Chiari, Alejandro Marcel Hasslocher-Moreno, Eliane Furtado Moreira, Divina Seila de Oliveira Marques, Eliane Lages Silva, José Antonio Marin-Neto, Lúcia Maria da Cunha Galvão, Sergio Salles Xavier, Sebastião Aldo da Silva Valente, Noêmia Barbosa Carvalho, Alessandra Viana Cardoso, Rafaella Albuquerque E Silva, Veruska Maia da Costa, Simone Monzani Vivaldini, Suelene Mamede Oliveira, Vera da Costa Valente, Mayara Maia Lima, Renato Vieira Alves
Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts. The disease represents a significant public health issue in Brazil, with different regional patterns. This document presents the evidence that resulted in the Brazilian Consensus on Chagas Disease. The objective was to review and standardize strategies for diagnosis, treatment, prevention, and control of Chagas disease in the country, based on the available scientific evidence...
December 2016: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/27941151/diagnosis-and-treatment-of-leishmaniasis-clinical-practice-guidelines-by-the-infectious-diseases-society-of-america-idsa-and-the-american-society-of-tropical-medicine-and-hygiene-astmh
#19
Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar M Carvalho, Moshe Ephros, Selma Jeronimo, Alan Magill
It is important to realize that leishmaniasis guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. The IDSA and ASTMH consider adherence to these guidelines to be voluntary, with the ultimate determinations regarding their application to be made by the physician in the light of each patient's individual circumstances.
December 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27941143/diagnosis-and-treatment-of-leishmaniasis-clinical-practice-guidelines-by-the-infectious-diseases-society-of-america-idsa-and-the-american-society-of-tropical-medicine-and-hygiene-astmh
#20
Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar M Carvalho, Moshe Ephros, Selma Jeronimo, Alan Magill
It is important to realize that leishmaniasis guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. The IDSA and ASTMH consider adherence to these guidelines to be voluntary, with the ultimate determinations regarding their application to be made by the physician in the light of each patient's individual circumstances.
December 15, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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