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https://www.readbyqxmd.com/read/28433809/biocorona-formation-on-gold-nanoparticles-modulates-human-proximal-tubule-kidney-cell-uptake-cytotoxicity-and-gene-expression
#1
M T Ortega, J E Riviere, K Choi, N A Monteiro-Riviere
Gold nanoparticles (AuNP) adsorb macromolecules to form a protein corona (PC) after systemic delivery, to which the kidney as the primary excretory organ is constantly exposed. The role of the PC on AuNP cell uptake and toxicity was investigated in vitro in human proximal tubule cells (HPTC) using 40 and 80nm branched polyethylenimine (BPEI), lipoic acid (LA) and polyethylene glycol (PEG) coated AuNP with or without (bare) PCs composed of human plasma (HP) or human serum albumin (HSA) for 0.25 to 24h. Time-dependent intracellular uptake, assessed by ICP-MS showed PC modulated cell uptake and cytotoxicity; with bare 40nm BPEI-AuNP showing the greatest responses...
April 19, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28432507/study-of-the-potential-of-barnyard-grass-for-the-remediation-of-cd-and-pb-contaminated-soil
#2
Jianling Xu, Qiongyao Cai, Hanxi Wang, Xuejun Liu, Jing Lv, Difu Yao, Yue Lu, Wei Li, Yuanyuan Liu
In this study, the microwave digestion method was used to determine total cadmium (Cd) and lead (Pb) concentrations, the BCR method was used to determine different states of Cd and Pb, and atomic absorption spectroscopy (AAS) and inductively coupled plasma optical emission spectrometry (ICP-OES) were used to determine Cd and Pb concentrations in simulated soil and barnyard grass before and after planting barnyard grass to provide a theoretical basis for the remediation of Cd- and Pb-contaminated soil. The results showed that the bioconcentration factor changes with different Cd concentrations are relatively complex and that the removal rate increases regularly...
May 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28431870/the-effect-of-hypertonic-saline-and-mannitol-on-coagulation-in-moderate-traumatic-brain-injury-patients
#3
Haifeng Wang, Hongshi Cao, Xiaohong Zhang, Liang Ge, Li Bie
BACKGROUND: Hyperosmolar therapy, using either hypertonic saline (HTS) or mannitol (MT), is considered the treatment of choice for intracranial hypertension, a disorder characterized by high intracranial pressure (ICP). However, hyperosmolar agents have been postulated to impair coagulation and platelet function. The aim of this study was to identify whether HTS and MT could affect coagulation in moderate traumatic brain injury (TBI) patients. METHODS: In this prospective and randomized double-blind study, we included adult patients with moderate TBI...
April 14, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28429272/electrocatalytic-dechlorination-of-2-3-5-trichlorophenol-on-palladium-carbon-nanotubes-nafion-film-titanium-mesh-electrode
#4
Zhirong Sun, Xiaoyue Ma, Xiang Hu
Palladium/carbon nanotubes-nafion film-modified titanium mesh electrode (Pd/CNTs-nafion film/Ti electrode) was prepared and used for catalytic dechlorination of 2,3,5-trichlorophenol (2,3,5-TCP). The influences of factors, such as Pd(2+) concentration, plating solution pH, and electrodeposition time and current, on the preparation of the electrode were studied by cyclic voltammetry (CV) to establish the optimal electrode preparation conditions. Additionally, the CV results highlighted that the addition of the CNTs-nafion film could enhance the electrochemical performance of the electrode...
April 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28427624/ultrasound-assisted-biodiesel-production-by-a-novel-composite-of-fe-iii-based-mof-and-phosphotangestic-acid-as-efficient-and-reusable-catalyst
#5
Ahmad Nikseresht, Asra Daniyali, Mahdi Ali-Mohammadi, Ahmad Afzalinia, Abbas Mirzaie
In this work, esterification of oleic acid by various alcohols is achieved with high yields under ultrasonic irradiation. This reaction performed with a novel heterogeneous catalyst that fabricated by heteropoly acid and Fe(III)-based MOF, namely MIL-53 (Fe). Syntheses of MIL-53 and encapsulation process carry out by ultrasound irradiation at ambient temperature and atmospheric pressure. The prepared composite was characterized by various techniques such as XRD, FT-IR, SEM, BET and ICP that demonstrate excellent catalytic activities, while being highly convenient to synthesize...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28425536/cisplatin-resistance-in-cell-models-evaluation-of-metallomic-and-biological-predictive-biomarkers-to-address-early-therapy-failure
#6
Marta Espina, Mario Corte-Rodríguez, Leticia Aguado, María Montes-Bayón, Marta I Sierra, Pablo Martínez-Camblor, Elisa Blanco-González, L María Sierra
Cisplatin, one of the most extensively used metallodrugs in cancer treatment, presents the important drawback of patient resistance. This resistance is the consequence of different processes including those preventing the formation of DNA adducts and/or their quick removal. Thus, a tool for the accurate detection and quantitation of cisplatin-induced adducts might be valuable for predicting patient resistance. To prove the validity of such an assumption, highly sensitive plasma mass spectrometry (ICP-MS) strategies were applied to determine DNA adduct levels and intracellular Pt concentrations...
April 20, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28425250/retrospective-analysis-of-maternal-fetal-and-neonatal-outcomesof-intrahepatic-cholestasis-of-pregnancy-at-gazi-university
#7
Berrin Günaydin, Merih Bayram, Melis Altuğ, Semra Cevher, Nuray Bozkurt
BACKGROUND/AIM: Maternal, fetal, and neonatal outcomes in parturients with intrahepatic cholestasis of pregnancy (ICP) have been retrospectively documented. We aimed to present pregnancy outcomes of parturients with ICP who underwent delivery. The study was conducted during a 1-year period. MATERIALS AND METHODS: After ethics committee approval, data from 1 January to 31 December 2015 were collected to identify parturients with ICP. RESULTS: Ten out of 37 patients underwent normal spontaneous vaginal delivery (NSVD), and the remaining 27 parturients underwent cesarean section (CS)...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28424959/non-essential-element-concentrations-in-brown-grain-rice-assessment-by-advanced-data-mining-techniques
#8
Roxana Villafañe, Melisa Hidalgo, Analía Piccoli, Eduardo Marchevsky, Roberto Pellerano
The concentrations of 17 non-essential elements (Al, As, Ba, Be, Cd, Ce, Cr, Hg, La, Li, Pb, Sb, Sn, Sr, Th, Ti, and Tl) were determined in brown grain rice samples of two varieties: Fortuna and Largo Fino. The samples were collected from the four main producing regions of Corrientes province (Argentina). Quantitative determinations were performed by inductively coupled plasma mass spectrometry (ICP-MS), using a validated method. The contents of As, Be, Cd, Ce, Cr, Hg, Pb, Sb, Sn, Th, and Tl were very low or not detected in most samples...
April 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28424825/a-magnetized-nanoparticle-based-solid-phase-extraction-procedure-followed-by-inductively-coupled-plasma-atomic-emission-spectrometry-to-determine-arsenic-lead-and-cadmium-in-water-milk-indian-rice-and-red-tea
#9
Salameh Azimi, Zarrin Es'haghi
A sensitive and simple method using magnetic multi-walled carbon nanotube (MWCNTs-Fe3O4 MNP), as the adsorbent, has been successfully developed for extraction and pre-concentration of arsenic, lead and cadmium with detection by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The nanosorbent was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction pattern (XRD), vibrating sample magnetometer (VSM) and transmission electron microscopy (TEM). The key factors affecting the signal intensity such as pH, adsorbent amount, etc...
April 19, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28424000/heavy-metals-and-pahs-in-canned-fish-supplies-on-the-serbian-market
#10
Nikolina J Novakov, Željko A Mihaljev, Brankica D Kartalović, Bojan J Blagojević, Jelana M Petrović, Miroslav A Ćirković, Dragan R Rogan
The aim of this study was to determine the level of heavy metals and PAHs in 57 samples of canned tuna, 25 samples of canned sardines and 16 samples of canned smoked sprouts, collected from supermarkets in Serbia. Heavy metal levels (lead, cadmium, mercury, arsenic, iron, copper and zinc) were determined using an ICP-MS method. Sixteen analyzed PAHs were determined using a GC-MS method. The trace elements in canned fish were in the range (mg kg(-1)) of 0.01-0.28 for lead, 0.003-0.08 for cadmium, 0.007-0.64 for mercury, 0...
April 20, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/28423108/-potential-health-risks-from-consumption-of-water-with-arsenic-in-colima-mexico
#11
Oliver Mendoza-Cano, Ramón Alberto Sánchez-Piña, Julián Barrón-Quintana, Herguin Benjamin Cuevas-Arellano, Pilar Escalante-Minakata, Ramón Solano-Barajas
Objective: To estimate potential health risks due to chronic ingestion of arsenic from groundwater in Colima, Mexico. Materials and methods: Samples were randomly taken in 36 wells from 10 local aquifers. Analysis was performed by ICP-OES following international standards. Geostatistical interpolation was performed with ArcGIS, implementing a model weighting inverse distance to estimate arsenic routes of exposure and consumption on each locality. The Hazard Quotient Ratio (HQ) and carcinogenic risk (R) for As were estimated...
January 2017: Salud Pública de México
https://www.readbyqxmd.com/read/28421189/optic-nerve-sheath-diameter-ultrasound-evaluation-in-intensive-care-unit-possible-role-and-clinical-aspects-in-neurological-critical-patients-daily-monitoring
#12
M Toscano, G Spadetta, P Pulitano, M Rocco, V Di Piero, O Mecarelli, E Vicenzini
Background. The increase of the optic nerve sheath diameter (ONSD) is a reliable, noninvasive sonographic marker of intracranial hypertension. Aim of the study was to demonstrate the efficacy of ONSD evaluation, when monitoring neurocritical patients, to early identify malignant intracranial hypertension in patients with brain death (BD). Methods. Data from ultrasound ONSD evaluation have been retrospectively analyzed in 21 sedated critical patients with neurological diseases who, during their clinical course, developed BD...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28420900/intracranial-pressure-monitoring-for-pediatric-acute-encephalopathy
#13
Nobuyuki Nosaka, Kohei Tsukahara, Emily Knaup, Toshihiko Yabuuchi, Tomonobu Kikkawa, Yosuke Fujii, Masato Yashiro, Takao Yasuhara, Ayumi Okada, Toyomu Ugawa, Atsunori Nakao, Hirokazu Tsukahara, Isao Date
Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management...
April 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28420186/using-moss-to-assess-airborne-heavy-metal-pollution-in-taizhou-china
#14
Xiaoli Zhou, Qin Chen, Chang Liu, Yanming Fang
Bryophytes act as bioindicators and bioaccumulators of metal deposition in the environment. To understand the atmospheric deposition of heavy metals (cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), nickel (Ni), lead (Pb), and zinc (Zn)) in Taizhou, East China, samples of moss (Haplocladium microphyllum) were collected from 60 sites selected by a systematic sampling method during the summer of 2012, and the concentrations of these heavy metals were determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES)...
April 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28418431/body-burdens-sources-and-interrelations-of-selected-toxic-and-essential-elements-among-the-nine-cree-first-nations-of-eeyou-istchee-james-bay-region-of-northern-quebec-canada
#15
Evert Nieboer, Ian D Martin, Eric N Liberda, Eric Dewailly, Elizabeth Robinson, Leonard J S Tsuji
BACKGROUND: this article constitutes a report on the comprehensive Nituuchischaayihtitaau Aschii multi-community environment-and-health study conducted among the Cree peoples (Eeyouch) of northern Quebec, Canada. OBJECTIVES: to interpret observed concentrations of a suite of chemical elements in a multi-media biological monitoring study in terms of sources and predictors. METHODS: the concentrations of 5 essential and 6 toxic chemical elements were measured in whole blood, and/or in urine or hair by ICP-MS...
April 18, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28417342/adipose-tissue-derived-stem-cell-therapy-for-erectile-dysfunction-in-rats-a-systematic-review-and-meta-analysis
#16
REVIEW
Quan-Liang Hou, Meng-Ying Ge, Cheng-da Zhang, Dan-Dan Tian, Lian-Ke Wang, Hui-Zi Tian, Wen-Hua Wang, Wei-Dong Zhang
OBJECTIVE: We aimed to systematically assess the effect of adipose tissue-derived stem cell (ADSC) therapy and its influential factors on the treatment of erectile dysfunction (ED) in rats. METHODS: Two authors independently searched for published studies through PubMed and EMBASE from study inception until August 31, 2016. A meta-analysis was used to combine the effect estimate from the published studies. A subgroup analysis was performed to identify the effect of some influential factors...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28417130/iron-isotopic-composition-of-blood-serum-in-anemia-of-chronic-kidney-disease
#17
Yulia Anoshkina, Marta Costas-Rodríguez, Marijn Speeckaert, Wim Van Biesen, Joris Delanghe, Frank Vanhaecke
Chronic kidney disease (CKD) is a general term for disorders that affect the structure and function of the kidneys. Iron deficiency (ID) and anemia occur in the vast majority of CKD patients, most of whom are elderly. However, establishing the cause of anemia in CKD, and therefore making an informed decision concerning the corresponding therapeutic treatment, is still a challenge. High-precision Fe isotopic analysis of blood serum samples of CKD patients with and without ID/anemia was performed via multi-collector inductively coupled plasma-mass spectrometry (MC-ICP-MS) for such a purpose...
April 18, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28415549/the-precursors-effects-on-biomimetic-hydroxyapatite-ceramic-powders
#18
Afife Binnaz Hazar Yoruç, Aysu Aydınoğlu
In this study, effects of the starting material on chemical, physical, and biological properties of biomimetic hydroxyapatite ceramic powders (BHA) were investigated. Characterization and chemical analysis of BHA powders were performed by using XRD, FT-IR, and ICP-AES. Microstructural features such as size and morphology of the resulting BHA powders were characterized by using BET, nano particle sizer, pycnometer, and SEM. Additionally, biological properties of the BHA ceramic powders were also investigated by using water-soluble tetrazolium salts test (WST-1)...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415463/in-vitro-characterisation-of-a-sol-gel-derived-in-situ-silica-coated-silicate-and-carbonate-co-doped-hydroxyapatite-nanopowder-for-bone-grafting
#19
Seyed Mohsen Latifi, Mohammadhossein Fathi, Ali Sharifnabi, Jaleh Varshosaz
Design and synthesis of materials with better properties and performance are essential requirements in the field of biomaterials science that would directly improve patient quality of life. For this purpose, in situ silica-coated silicate and carbonate co-doped hydroxyapatite (Sc/S.C.HA) nanopowder was synthesized via the sol-gel method. Characterisation of the prepared nanopowder was carried out by XRD, FTIR, TEM, SEM, EDX, ICP, zeta potential, acid dissolution test, and cell culture test. The substitution of the silicate and carbonate ions into hydroxyapatite structure was confirmed by FTIR analysis...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415449/complementary-approaches-for-the-evaluation-of-biocompatibility-of-90-y-labeled-superparamagnetic-citric-acid-fe-er-3o4-coated-nanoparticles
#20
Bratislav Antic, Marko Boskovic, Jasmina Nikodinovic-Runic, Yue Ming, Hongguo Zhang, Emil S Bozin, Drina Janković, Vojislav Spasojevic, Sanja Vranjes-Djuric
Magnetic nanoparticles (MNPs) are of immense interest for diagnostic and therapeutic applications in medicine. Design and development of new iron oxide-based MNPs for such applications is of rather limited breadth without reliable and sensitive methods to determine their levels in body tissues. Commonly used methods, such as ICP, are quite problematic, due to the inability to decipher the origin of the detected iron, i.e. whether it originates from the MNPs or endogenous from tissues and bodily fluids. One of the approaches to overcome this problem and to increase reliability of tracing MNPs is to partially substitute iron ions in the MNPs with Er...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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