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https://www.readbyqxmd.com/read/27914280/trace-isotope-analysis-of-ricinus-communis-seed-core-for-provenance-determination-by-laser-ablation-icp-ms
#1
Christina K Bagas, Rachel L Scadding, Cameron J Scadding, R John Watling, Warren Roberts, Simon P B Ovenden
The castor bean plant, Ricinus communis, grows wild throughout many regions of Australia. The seeds of the plant contain the schedule 1 chemical agent ricin, a type II ribosomal inhibiting protein. Currently there are limited analytical techniques that can be applied in analysis of the seeds to establish attribution. In this study, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was used for the analysis of seeds collected from 68 plants across 38 locations around Australia. Of the 92 elemental isotopes measured, fifteen ((24)Mg, (27)Al, (44)Ca, (53)Cr, (55)Mn, (57)Fe, (60)Ni, (65)Cu, (66)Zn, (75)As, (85)Rb, (88)Sr, (98)Mo, (138)Ba and (202)Hg) yielded data that were relevant to all collection sites...
November 25, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27913831/high-transport-efficiency-of-nanoparticles-through-a-total-consumption-sample-introduction-system-and-its-beneficial-application-for-particle-size-evaluation-in-single-particle-icp-ms
#2
Shin-Ichi Miyashita, Hiroaki Mitsuhashi, Shin-Ichiro Fujii, Akiko Takatsu, Kazumi Inagaki, Toshiyuki Fujimoto
In order to facilitate reliable and efficient determination of both the particle number concentration (PNC) and the size of nanoparticles (NPs) by single-particle ICP-MS (spICP-MS) without the need to correct for the particle transport efficiency (TE, a possible source of bias in the results), a total-consumption sample introduction system consisting of a large-bore, high-performance concentric nebulizer and a small-volume on-axis cylinder chamber was utilized. Such a system potentially permits a particle TE of 100 %, meaning that there is no need to include a particle TE correction when calculating the PNC and the NP size...
December 2, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27909780/interrogating-the-variation-of-element-masses-and-distribution-patterns-in-single-cells-using-icp-ms-with-a-high-efficiency-cell-introduction-system
#3
Hailong Wang, Meng Wang, Bing Wang, Lingna Zheng, Hanqing Chen, Zhifang Chai, Weiyue Feng
Cellular heterogeneity is an inherent condition of cell populations, which results from stochastic expression of genes, proteins, and metabolites. The heterogeneity of individual cells can dramatically influence cellular decision-making and cell fate. So far, our knowledge about how the variation of endogenous metals and non-metals in individual eukaryotic cells is limited. In this study, ICP-MS equipped with a high efficiency cell introduction system (HECIS) was developed as a method of single-cell ICP-MS (SC-ICP-MS)...
December 1, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27909561/korean-solar-salts-reduce-obesity-and-alter-its-related-markers-in-diet-induced-obese-mice
#4
Jaehyun Ju, Jia-Le Song, Eui-Seong Park, Myoung-Sool Do, Kun-Young Park
BACKGROUND/OBJECTIVES: The aim of this experiments was to show anti-obesity effects of Korean solar salt from different salt fields in diet-induced obese mice. SUBJECTS/METHODS: Diet-induced obesity (DIO) was induced by a high-fat diet (HFD; 45% cal from fat) in C57BL/6J mice for eight weeks. The mice were fed with the designated diets (chow diet for Normal, HFD for Control, 0.47%-salt-mixed HFD for purified salt (PS), Guerande solar salt from France (SS-G), solar salt from Y salt field (SS-Y), solar salts from T salt field (SS-T) and S salt field (SS-S)) for another eight weeks...
December 2016: Nutrition Research and Practice
https://www.readbyqxmd.com/read/27908430/evaluation-of-tissue-metal-and-trace-element-content-in-a-rat-model-of-non-alcoholic-fatty-liver-disease-using-icp-drc-ms
#5
Eugenia R Gatiatulina, Elizaveta V Popova, Valentina S Polyakova, Anastasia A Skalnaya, Eduard F Agletdinov, Alexandr A Nikonorov, Anatoly V Skalny, Alexey A Tinkov
The primary objective of the study was to assess the level of metals and trace elements in liver, serum, and hair of rats with diet-induced non-alcoholic fatty liver disease (NAFLD) using inductively coupled plasma dynamic reaction cell mass spectrometer (ICP-DRC-MS). 56 female 3-months-old Wistar rats divided into two equal groups were fed either standard (10% calories from fat) or high-fat high-carbohydrate diet (60% calories from fat in chow and 10% sucrose solution) for 6 weeks. Serum was examined for insulin resistance markers, lipid profile, and alanine aminotransferase (ALT) activity...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908426/environmental-exposures-of-trace-elements-assessed-using-keratinized-matrices-from-patients-with-chronic-kidney-diseases-of-uncertain-etiology-ckdu-in-sri-lanka
#6
Saranga Diyabalanage, Sanjeewani Fonseka, D M S N B Dasanayake, Rohana Chandrajith
An alarming increase in chronic kidney disease with unknown etiology (CKDu) has recently been reported in several provinces in Sri Lanka and chronic exposures to toxic trace elements were blamed for the etiology of this disease. Keratinized matrices such as hair and nails were investigated to determine the possible link between CKDu and toxic element exposures. Elements Li, B, Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Ba, Hg and Pb of hair and nails of patients and age that matched healthy controls were determined with Inductively Coupled Plasma Mass Spectrometry (ICP-MS)...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908409/evaluation-of-sulfur-isotopic-enrichment-of-urine-metabolites-for-the-differentiation-of-healthy-and-prostate-cancer-mice-after-the-administration-of-34-s-labelled-yeast
#7
Oscar Galilea San Blas, Fernando Moreno Sanz, Pilar Herrero Espílez, Rosa María Sainz Menéndez, Juan Carlos Mayo Barallo, Juan Manuel Marchante-Gayón, José Ignacio García Alonso
Sulfur isotopic enrichment of urine metabolites in healthy and prostate cancer mice using (34)S enriched yeast and High Performance Liquid Chromatography coupled to Multicollector Inductively Coupled Plasma Mass Spectrometry (HPLC-MC-ICP-MS) has been evaluated. A 30 weeks experiment (since the eleventh to the fortieth week of life) was carried out collecting the urine of three healthy mice and three transgenic mice with prostate cancer during 24h after a single oral administration of a (34)S enriched yeast slurry...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908408/protective-effect-of-magnesium-acetyltaurate-against-nmda-induced-retinal-damage-involves-restoration-of-minerals-and-trace-elements-homeostasis
#8
Azliana Jusnida Ahmad Jafri, Natasha Najwa Nor Arfuzir, Lidawani Lambuk, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Norhafiza Razali, Anna Krasilnikova, Maria Kharitonova, Vasily Demidov, Evgeny Serebryansky, Anatoly Skalny, Alexander Spasov, Ahmad Pauzi Md Yusof, Nafeeza Mohd Ismail
Glutamate-mediated excitotoxicity involving N-methyl-d-aspartate (NMDA) receptors has been recognized as a final common outcome in pathological conditions involving death of retinal ganglion cells (RGCs). Overstimulation of NMDA receptors results in influx of calcium (Ca) and sodium (Na) ions and efflux of potassium (K). NMDA receptors are blocked by magnesium (Mg). Such changes due to NMDA overstimulation are also associated with not only the altered levels of minerals but also that of trace elements and redox status...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27907158/effects-of-exposure-to-blast-overpressure-on-intracranial-pressure-and-blood-brain-barrier-permeability-in-a-rat-model
#9
Usmah Kawoos, Ming Gu, Jason Lankasky, Richard M McCarron, Mikulas Chavko
Exposure to blast overpressure (BOP) activates a cascade of pathological processes including changes in intracranial pressure (ICP) and blood-brain barrier (BBB) permeability resulting in traumatic brain injury (TBI). In this study the effect of single and multiple exposures at two intensities of BOP on changes in ICP and BBB permeability in Sprague-Dawley rats was evaluated. Animals were exposed to a single or three repetitive (separated by 0.5 h) BOPs at 72 kPa or 110 kPa. ICP was monitored continuously via telemetry for 6 days after exposure to BOP...
2016: PloS One
https://www.readbyqxmd.com/read/27906948/cervical-interlaminar-epidural-injections-at-high-doses-do-not-increase-optic-nerve-sheath-diameter-on-a-long-term-basis
#10
Hyunzu Kim, Joo Hyeon O, Sung-Jun Hong, Keun Man Shin, JungChan Park, Sang Soo Kang
BACKGROUND: Cervical epidural injection (CEI) is widely performed on patients with pain originating from the cervical spine. Studies have shown a good relationship between the optic nerve sheath diameter (ONSD) and the intracranial pressure (ICP). OBJECTIVE: The aim of this study was to evaluate the changes in the ONSD as a non-invasive surrogate marker of ICP after CEI. STUDY DESIGN: Prospective observational study. SETTING: Hospital and ambulatory pain clinic...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27906426/continuous-monitoring-of-intracranial-pressure-for-prediction-of-postoperative-complications-of-hypertensive-intracerebral-hemorrhage
#11
S-X Yu, Q-S Zhang, Y Yin, Z Liu, J-M Wu, M-X Yang
OBJECTIVE: This study evaluates the value of continuous dynamic monitoring of intracranial pressure (ICP) in patients with hypertensive intracerebral hemorrhage to predict early postoperative complications. PATIENTS AND METHODS: Data from 80 patients treated in our hospital from February 2014 to February 2015 were analyzed. The patients all underwent decompressive craniectomies, and their ICP changes were monitored invasively and continuously for 1 to 7 days after surgery...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27905283/comparative-analysis-of-serum-mineral-levels-and-parasite-load-in-goats-naturally-infected-with-gastrointestinal-nematodes
#12
Serap Ünübol Aypak, Süleyman Aypak, Hüseyin Voyvoda, Gülşen Güven, Evrim Dereli Fidan, Gamze Tosun, Mehmet Gültekin, Emrah Şimşek, Asude Gülçe Güler
OBJECTIVE: This study aimed to investigate the relationship between serum mineral levels and parasite load in Saanen (n=37) and Damascus (n=13) goats, which were all approximately 2 months pregnant and naturally infected with gastrointestinal nematodes. METHODS: To determine parasite concentration individually, fecal samples were taken from each goat, and the eggs per gram (EPG) of feces was detected via a modified McMaster technique. To investigate the possible effects of parasite concentration on serum mineral levels, blood was drawn from the goats and serum calcium, phosphorus, magnesium, iron, copper, zinc, manganese, nickel, and cadmium levels were measured via the ICP-OES technique...
September 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/27903020/dynamic-decompressive-craniotomy-with-a-novel-reversibly-expandable-plate
#13
Rohit Khanna
Objective To assess the feasibility of a dynamic craniotomy procedure with the use of a novel reversibly expandable cranial bone flap fixation plate. The expandable plate allows outward bone flap migration with an increase in intracranial volume or intracranial pressure (ICP). Methods Dynamic craniotomy intracranial hypertension compliance was evaluated in a skull model with progressive increase in intracranial volume and compared with the standard craniotomy with fixed plates. Results Dynamic craniotomy provided significant control of ICP with increasing intracranial volume compared with the standard craniotomy...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27903013/isoflurane-associated-mydriasis-mimicking-blown-pupils-in-a-patient-treated-in-a-neurointensive-care-unit
#14
Eva Magdalena Korf, Volker Martin Tronnier, Jan Gliemroth, Jan Nils Küchler
We report a misinterpretation of bilateral mydriasis as blown pupils related to elevated intracranial pressure (ICP) under volatile sedation with isoflurane (Anesthetic Conserving Device [AnaConDa], Hudson RCI, Uppland Vasby, Sweden) in a 59-year-old patient with a severe traumatic brain injury with frontal contusion. The patient showed bilateral mydriasis and a missing light reflex 8 hours after changing sedation from intravenous treatment with midazolam and esketamine to volatile administration of isoflurane...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27900951/tuning-the-morphology-luminescence-and-magnetic-properties-of-hexagonal-phase-nagdf4-yb-er-nanocrystals-via-altering-the-addition-sequence-of-the-precursors
#15
Shuwen Zhao, Donglin Xia, Ruimin Zhao, Hao Zhu, Yiru Zhu, Yuda Xiong, Youfa Wang
Hexagonal-phase NaGdF4: Yb, Er upconversion nanocrystals (UCNCs) with tunable morphology and properties were successfully prepared via a thermal decomposition method. The influences of the adding sequence of the precursors on the morphology, chemical composition, luminescence and magnetic properties were investigated by transmission electron microscopy (TEM), inductively coupled plasma-atomic emission spectrometry (ICP-AES), upconversion (UC) spectroscopy, and a vibrating sample magnetometer (VSM). It was found that the resulting nanocrystals, with different sizes ranging from 24 to 224 nm, are in the shape of spheres,  hexagonal plates and flakes; moreover, the composition percentage of Yb(3+)-Er(3+) and Gd(3+) ions was found to vary in a regular pattern with the adding sequence...
November 30, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27898038/a-method-for-determining-the-content-of-glycoproteins-in-biological-samples
#16
Yang Gao, Duoduo Xu, Hongyue Li, Xianling Yang, Mingxing Wang, Qipin Gao
The glycoprotein purified from the mycelium extract of Tremella fuciformis was marked with iodine through the iodine substitution reaction. The content of iodine, which is indicative of the amount of the marked tremella glycoprotein (ITG), was detected with Inductively coupled plasma mass spectrometry (ICP-MS). The method was found to be stable, sensitive, and accurate at detecting the content of iodine-substituted glycoprotein, and was used in the quantitative analysis of biological samples, including blood and organs...
November 26, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27896228/the-european-innovation-partnership-on-active-and-healthy-ageing-synergies-protocol-for-a-prospective-observational-study-to-measure-the-impact-of-a-community-based-program-on-prevention-and-mitigation-of-frailty-icp-pmf-in-community-dwelling-older-adults
#17
G Liotta, F Orfila, M Vollenbroek-Hutten, R Roller-Winsberger, M Illario, D Musian, S Alvino, R O'Caoimh, A Cano, W Molloy, G Iaccarino, M C Marazzi, M C Inzerilli, O Madaro, C Paul, P Csonka, A C Vince, E Menditto, M Maggio, P Scarcella, F Gilardi, F Lucaroni, P Abete, V Girardi, R Barra, L Palombi
Aim of this paper is to describe the protocol of the study "Impact of a Community-based Program on Prevention and Mitigation of Frailty in community-dwelling older adults" developed in the framework of the European Innovation Partnership on Active and Healthy Ageing. This proposal has been developed by the Partnership Action groups on frailty, fall prevention and polypharmacy in older. The proposal wants to assess the impact of community-based programs aimed to counteract three main outcomes related to frailty: hospitalization, institutionalization and death...
November 2016: Translational Medicine @ UniSa
https://www.readbyqxmd.com/read/27895924/urinary-arsenic-species-concentration-in-residents-living-near-abandoned-metal-mines-in-south-korea
#18
Jin-Yong Chung, Byoung-Gwon Kim, Byung-Kook Lee, Jai-Dong Moon, Joon Sakong, Man Joong Jeon, Jung-Duck Park, Byung-Sun Choi, Nam-Soo Kim, Seung-Do Yu, Jung-Wook Seo, Byeong-Jin Ye, Hyoun-Ju Lim, Young-Seoub Hong
BACKGROUND: Arsenic is a carcinogenic heavy metal that has a species-dependent health effects and abandoned metal mines are a source of significant arsenic exposure. Therefore, the aims of this study were to analyze urinary arsenic species and their concentration in residents living near abandoned metal mines and to monitor the environmental health effects of abandoned metal mines in Korea. METHODS: This study was performed in 2014 to assess urinary arsenic excretion patterns of residents living near abandoned metal mines in South Korea...
2016: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27895895/allergy-immunotherapy-across-the-life-cycle-to-promote-active-and-healthy-ageing-from-research-to-policies-an-airways-integrated-care-pathways-icps-programme-item-action-plan-b3-of-the-european-innovation-partnership-on-active-and-healthy-ageing-and-the-global
#19
REVIEW
M A Calderon, P Demoly, T Casale, C A Akdis, C Bachert, M Bewick, B M Bilò, B Bohle, S Bonini, A Bush, D P Caimmi, G W Canonica, V Cardona, A M Chiriac, L Cox, A Custovic, F De Blay, P Devillier, A Didier, G Di Lorenzo, G Du Toit, S R Durham, P Eng, A Fiocchi, A T Fox, R Gerth van Wijk, R M Gomez, T Haathela, S Halken, P W Hellings, L Jacobsen, J Just, L K Tanno, J Kleine-Tebbe, L Klimek, E F Knol, P Kuna, D E Larenas-Linnemann, A Linneberg, M Matricardi, H J Malling, R Moesges, J Mullol, A Muraro, N Papadopoulos, G Passalacqua, E Pastorello, O Pfaar, D Price, P Rodriguez Del Rio, R Ruëff, B Samolinski, G K Scadding, G Senti, M H Shamji, A Sheikh, J C Sisul, D Sole, G J Sturm, A Tabar, R Van Ree, M T Ventura, C Vidal, E M Varga, M Worm, T Zuberbier, J Bousquet
Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing...
2016: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/27894122/b-cell-lymphoma-2-modified-bone-marrow-derived-mesenchymal-stem-cells-transplantation-for-the-treatment-of-diabetes-mellitus-induced-erectile-dysfunction-in-a-rat-model
#20
Xiang Sun, Long-Hua Luo, Liang Feng, Dong-Shui Li, Ke-Zhao Zhong
OBJECTIVE: The study aimed to explore the effects of B cell lymphoma-2 (Bcl-2)-modified bone marrow-derived mesenchymal stem cells (BMSCs) transplantation for the treatment of diabetes mellitus-induced erectile dysfunction (DMED) in a rat model. METHODS: The DMED rat model was successfully established. Thirty-six DMED rats were assigned into the Bcl-2-BMSCs, null-BMSCs, BMSCs and phosphate buffered saline (PBS) groups. Meanwhile, 9 normal rats injected with PBS were taken as the normal control group...
November 29, 2016: Urologia Internationalis
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