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https://www.readbyqxmd.com/read/29166511/primary-cutaneous-follicle-center-lymphoma
#1
Eline Pinheiro Weba Costa, Bethänia Dias de Lucena, Gabriela Athayde Amin, Maraya de Jesus Semblano Bittencourt, Leonidas Braga Dias, Carla Andréa Avelar Pires
Cutaneous lymphomas are classified according to their cellular origin into T-cell lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000 population. We report a case of a 56-year-old male patient who presented with a two-month history of nodules of varying sizes, some ulcerated, on the face, abdomen, and upper limbs. Histopathological examination and immunohistochemical study confirmed the diagnosis of primary cutaneous centrofollicular lymphoma. Studies have shown an increased incidence of non-Hodgkin lymphomas in the last decade...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29163196/an-inertial-sensor-based-method-for-estimating-the-athlete-s-relative-joint-center-positions-and-center-of-mass-kinematics-in-alpine-ski-racing
#2
Benedikt Fasel, Jörg Spörri, Pascal Schütz, Silvio Lorenzetti, Kamiar Aminian
For the purpose of gaining a deeper understanding of the relationship between external training load and health in competitive alpine skiing, an accurate and precise estimation of the athlete's kinematics is an essential methodological prerequisite. This study proposes an inertial sensor-based method to estimate the athlete's relative joint center positions and center of mass (CoM) kinematics in alpine skiing. Eleven inertial sensors were fixed to the lower and upper limbs, trunk, and head. The relative positions of the ankle, knee, hip, shoulder, elbow, and wrist joint centers, as well as the athlete's CoM kinematics were validated against a marker-based optoelectronic motion capture system during indoor carpet skiing...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29162384/relevance-dependent-modulation-of-tactile-suppression-during-active-passive-and-pantomime-reach-to-grasp-movements
#3
Damian M Manzone, J Timothy Inglis, Ian M Franks, Romeo Chua
When we move, our ability to detect tactile events on the moving limb is reduced (e.g., movement-related tactile suppression). This process prevents unimportant sensory information from bombarding our central nervous system. This study investigated whether movement-related suppression can be modulated according to task relevance, while introducing a novel motor-driven complex upper limb movement. In three experiments participants performed volitional self-driven and passive motor-driven reaching and grasping movements...
November 18, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29162116/health-related-quality-of-life-handgrip-strength-and-falls-during-detraining-in-elderly-habitual-exercisers
#4
Izaro Esain, Ana Rodriguez-Larrad, Iraia Bidaurrazaga-Letona, Susana María Gil
BACKGROUND: The effects of regular exercise on physical functioning and health-related quality of life (HRQOL) have been thoroughly studied. In contrast, little is known about the changes which occur following cessation of activity (detraining). Here, we have investigated the effect of a 3 month detraining period on HRQOL and on handgrip strength in elderly people who had regularly exercised, and examined the association of these variables with falls. METHODS: Thirty-eight women and 11 men (mean age, 75...
November 21, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29161264/proprioceptive-assessment-in-clinical-settings-evaluation-of-joint-position-sense-in-upper-limb-post-stroke-using-a-robotic-manipulator
#5
Sara Contu, Asif Hussain, Simone Kager, Aamani Budhota, Vishwanath A Deshmukh, Christopher W K Kuah, Lester H L Yam, Liming Xiang, Karen S G Chua, Lorenzo Masia, Domenico Campolo
Proprioception is a critical component for motor functions and directly affects motor learning after neurological injuries. Conventional methods for its assessment are generally ordinal in nature and hence lack sensitivity. Robotic devices designed to promote sensorimotor learning can potentially provide quantitative precise, accurate, and reliable assessments of sensory impairments. In this paper, we investigate the clinical applicability and validity of using a planar 2 degrees of freedom robot to quantitatively assess proprioceptive deficits in post-stroke participants...
2017: PloS One
https://www.readbyqxmd.com/read/29160372/an-experimental-study-of-ascorbic-acid-effects-in-acute-renal-failure-under-general-anesthesia
#6
Omur Ozturk, Sefer Ustebay, Huseyin Avni Eroglu, Murat Günay, Yasemen Adali, İlksen Donmez, Mesut Erbas
PURPOSE: To evaluate the preventive effect of ascorbic acid on sevoflurane-induced acute renal failure in an experimental rat model. METHODS: Twenty-four adult male Wistar rats were randomly distributed into three groups. Subjects were allocated into 3 groups: Group I received sevoflurane only, whereas Groups II and III had moderate (150 mg/kg) and high (300 mg/kg) doses of AA in addition to sevoflurane, respectively. Rhabdomyolysis and myohemoglobinuric ARF was formed by intramuscular administration of glycerol on the upper hind limb on the 15th minute of inhalation anesthesia...
October 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29160240/remapping-cortical-modulation-for-electrocorticographic-brain-computer-interfaces-a-somatotopy-based-approach-in-individuals-with-upper-limb-paralysis
#7
Alan D Degenhart, Shivayogi V Hiremath, Ying Yang, Stephen T Foldes, Jennifer L Collinger, Michael L Boninger, Elizabeth C Tyler-Kabara, Wei Wang
OBJECTIVE: Brain-computer interface (BCI) technology aims to provide individuals with paralysis a means to restore function. Electrocorticography (ECoG) uses disc electrodes placed on either the surface of the dura or the cortex to record field potential activity. ECoG has been proposed as a viable neural recording modality for BCI systems, potentially providing stable, long-term recordings of cortical activity with high spatial and temporal resolution. Previously we have demonstrated that a subject with spinal cord injury (SCI) could control an ECoG-based BCI system with up to three degrees of freedom [Wang et al...
November 21, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29160145/the-graded-and-redefined-assessment-of-strength-sensibility-and-prehension-grassp-version-2-provides-interval-measure-properties
#8
Inge-Marie Velstra, Carolina Saskia Fellinghauer, Rainer Frank Abel, Sukhvinder Kalsi-Ryan, Rüdiger Rupp, Armin Curt
The GRASSP is a valid, reliable and responsive outcome measure to evaluate upper limb function in individuals with tetraplegia. GRASSP generates ordinal total scores; thus, applicability as an interval level measurement requires testing of its measurement properties. Therefore, this study examined the metric characteristics with Rasch analysis to derive interval level scales of the respective GRASSP subtests. The GRASSP was recorded within 10 days, at 1, 3, 6 and 12 months after cervical spinal cord injury (SCI)...
November 21, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29159899/extremely-painful-multifocal-acquired-predominant-axonal-sensorimotor-neuropathy-of-the-upper-limb
#9
Doris Lieba-Samal, Jeroen J J van Eijk, Marieke H J van Rosmalen, Irene M F van Balken, Aad Verrips, Jop Mostert, Sigrid Pillen, Nens van Alfen
The differential diagnosis of upper extremity mononeuritis multiplex includes neuralgic amyotrophy, vasculitic neuropathy, and Lewis-Sumner syndrome. We describe 3 patients initially suspected of neuralgic amyotrophy, who had an extremely painful, protracted, progressive disease course, not fitting one of these established diagnoses. Nerve ultrasonography showed focal caliber changes of the roots, plexus, and limb nerves. Electromyography showed predominant multifocal axonopathy. Ongoing autoimmune neuropathy was suspected...
November 21, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29159873/orthopaedic-manifestations-within-the-22q11-2-deletion-syndrome-a-systematic-review
#10
Jelle F Homans, Isabel N Tromp, Dino Colo, Tom P C Schlösser, Moyo C Kruyt, Vincent F X Deeney, Terrence B Crowley, Donna M McDonald-McGinn, René M Castelein
The 22q11.2 Deletion Syndrome (22q11.2DS) is the most common microdeletion syndrome with an estimated prevalence of 1:4,000 live births. 22q11.2DS is known to have wide phenotypic variability, including orthopaedic manifestations. The purpose of this systematic review is to increase the awareness of orthopaedic manifestations associated with 22q11.2DS. This systematic review was performed according to the PRISMA Guidelines. Original epidemiological studies on the prevalence of orthopaedic manifestations within 22q11...
November 21, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29159193/prep2-a-biomarker-based-algorithm-for-predicting-upper-limb-function-after-stroke
#11
Cathy M Stinear, Winston D Byblow, Suzanne J Ackerley, Marie-Claire Smith, Victor M Borges, P Alan Barber
Objective: Recovery of motor function is important for regaining independence after stroke, but difficult to predict for individual patients. Our aim was to develop an efficient, accurate, and accessible algorithm for use in clinical settings. Clinical, neurophysiological, and neuroimaging biomarkers of corticospinal integrity obtained within days of stroke were combined to predict likely upper limb motor outcomes 3 months after stroke. Methods: Data from 207 patients recruited within 3 days of stroke [103 females (50%), median age 72 (range 18-98) years] were included in a Classification and Regression Tree analysis to predict upper limb function 3 months poststroke...
November 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29159074/only-some-patients-with-bulbar-and-spinal-muscular-atrophy-may-develop-cardiac-disease
#12
Josef Finsterer, Claudia Stöllberger
Objectives: According to recent publications, some patients with spinal and bulbar muscular atrophy (BSMA) develop cardiac disease, manifesting as ST-segment abnormalities, Brugada-syndrome, dilative cardiomyopathy, or sudden cardiac death. Here we present neurological and cardiac data of a BSMA patient who was followed up for 10 y. Case report: In a male patient aged 47 y, BSMA was diagnosed at age 37 y upon the typical clinical presentation (postural tremor since age 12 y, dysarthria since age 15 y, muscle cramps since age 29 y, general myalgias since age 32 y, general fasciculations since age 34 y, myoclonic jerks, easy fatigability, dyspnea upon exercise since age 36 y) and a CAG-repeat expansion of 47 ± 1 repeats in the androgen-receptor gene detected at age 37 y...
March 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29159007/acute-brachial-artery-occlusion-in-an-elderly-patient-with-acute-myocardial-ischemia
#13
Gabriel O Ologun, Christian Bohan, Tiffany Lau, Mohammad Sultany, Andrew Trecartin, Zachary Wolfe, Silviu Marica, Lawrence Sampson, Umashankar Ballehaninna
We present a case of left upper extremity paresis secondary to acute brachial artery occlusion in an elderly female with active non-ST segment elevation myocardial ischemia (NSTEMI) in the setting of paroxysmal atrial fibrillation. The patient was initially suspected to have a cerebrovascular attack (CVA); however, computed tomography (CT) head was negative for acute stroke. The diagnosis was confirmed by computed tomographic angiography (CTA) of the upper extremity, confirming the diagnosis of acute left brachial artery occlusion...
September 19, 2017: Curēus
https://www.readbyqxmd.com/read/29158692/pulsed-radiofrequency-of-brachial-plexus-under-ultrasound-guidance-for-refractory-stump-pain-a-case-report
#14
Bixin Zheng, Li Song, Hui Liu
The post-amputation (pain) syndrome, including stump pain, phantom limb sensation, and phantom limb pain is common but difficult to treat. Refractory stump pain in the syndrome is an extremely challenging and troublesome clinical condition. Patients respond poorly to drugs, nerve blocks, and other effective treatments like spinal cord stimulation and surgery. Pulsed radiofrequency (PRF) technique has been shown to be effective in reducing neuropathic pain. This report describes a patient with persistent and refractory upper limb stump pain being successfully relieved with PRF of brachial plexus under ultrasound guidance after a 6-month follow-up period, suggesting that PRF may be considered as an alternative treatment for refractory stump-neuroma pain...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29157315/botulinum-toxin-type-a-injections-as-monotherapy-for-upper-limb-essential-tremor-using-kinematics
#15
Olivia Samotus, Niraj Kumar, Philippe Rizek, Mandar Jog
BACKGROUND: There is a significant need for a targeted therapy for essential tremor (ET), as medications have not been developed specifically for ET, and the ones prescribed are often not well-tolerated, so that many patients remain untreated. Recent work has shown that, unlike previous experience, kinematically guided individualized botulinum toxin type A (BoNT-A) injections provide benefit along with minimal weakness. Ours is the first long-term (96-week) safety and efficacy study of BoNT-A as monotherapy for ET using kinematically driven injection parameters...
November 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29157212/fine-motor-skills-in-a-population-of-children-in-remote-australia-with-high-levels-of-prenatal-alcohol-exposure-and-fetal-alcohol-spectrum-disorder
#16
Robyn Doney, Barbara R Lucas, Rochelle E Watkins, Tracey W Tsang, Kay Sauer, Peter Howat, Jane Latimer, James P Fitzpatrick, June Oscar, Maureen Carter, Elizabeth J Elliott
BACKGROUND: Many children in the remote Fitzroy Valley region of Western Australia have prenatal alcohol exposure (PAE). Individuals with PAE can have neurodevelopmental impairments and be diagnosed with one of several types of Fetal Alcohol Spectrum Disorder (FASD). Fine motor skills can be impaired by PAE, but no studies have developed a comprehensive profile of fine motor skills in a population-based cohort of children with FASD. We aimed to develop a comprehensive profile of fine motor skills in a cohort of Western Australian children; determine whether these differed in children with PAE or FASD; and establish the prevalence of impairment...
November 21, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29157154/risk-assessments-using-the-strain-index-and-the-tlv-for-hal-part-ii-multi-task-jobs-and-prevalence-of-cts
#17
Jay M Kapellusch, Barbara A Silverstein, Stephen S Bao, Mathew S Thiese, Andrew S Merryweather, Kurt T Hegmann, Arun Garg
BACKGROUND: The Strain Index (SI) and the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value for Hand Activity Level (TLV for HAL) have been shown to be associated with prevalence of distal upper limb musculoskeletal disorders such as carpal tunnel syndrome (CTS). The SI and TLV for HAL disagree on more than half of task exposure classifications. Similarly, Time-Weighted-Average (TWA), Peak, and Typical exposure techniques used to quantity physical exposure from multi-task jobs have shown between-technique agreement ranging from 61% to 93%, depending upon whether the SI or TLV for HAL model was used...
November 20, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29156493/virtual-reality-for-stroke-rehabilitation
#18
REVIEW
Kate E Laver, Belinda Lange, Stacey George, Judith E Deutsch, Gustavo Saposnik, Maria Crotty
BACKGROUND: Virtual reality and interactive video gaming have emerged as recent treatment approaches in stroke rehabilitation with commercial gaming consoles in particular, being rapidly adopted in clinical settings. This is an update of a Cochrane Review published first in 2011 and then again in 2015. OBJECTIVES: Primary objective: to determine the efficacy of virtual reality compared with an alternative intervention or no intervention on upper limb function and activity...
November 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29156324/influence-of-post-stroke-spasticity-on-emg-force-coupling-and-force-steadiness-in-biceps-brachii
#19
Jennilee K Carlyle, George Mochizuki
BACKGROUND: Individuals with spasticity after stroke experience a decrease in force steadiness which can impact function. Alterations in the strength of EMG-force coupling may contribute to the reduction in force steadiness observed in spasticity. The aim was to determine the extent to which force steadiness and EMG-force coupling is affected by post-stroke spasticity. METHODS: This cross-sectional study involved individuals with upper limb spasticity after stroke...
November 13, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29155725/an-efficient-and-reproducible-protocol-for-distraction-osteogenesis-in-a-rat-model-leading-to-a-functional-regenerated-femur
#20
Martine Pithioux, Flavy Roseren, Christian Jalain, Franck Launay, Philippe Charpiot, Patrick Chabrand, Sandrine Roffino, Edouard Lamy
This protocol describes the use of a newly developed external fixator for distraction osteogenesis in a rat femoral model. Distraction osteogenesis (DO) is a surgical technique leading to bone regeneration after an osteotomy. The osteotomized extremities are moved away from each other by gradual distraction to reach the desired elongation. This procedure is widely used in humans for lower and upper limb lengthening, treatment after a bone nonunion, or the regeneration of a bone defect following surgery for bone tumor excision, as well as in maxillofacial reconstruction...
October 23, 2017: Journal of Visualized Experiments: JoVE
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