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https://www.readbyqxmd.com/read/28549365/-giant-tumor-from-the-nerve-sheath
#1
L M Díaz-Rojas, A Lorente-Gómez, R Lorente-Moreno
A schwannoma is a benign nerve sheath tumor derived from Schwann cells. They are usually small and solitary tumors more frequently localized in cranial nerves and the spinal cord and rarely in the limbs. Some cases have been reported involving extremities (mainly the upper ones) but with a small size. Cases of big size schwannomas unrelated to a neurofibromatosis are very rare. We report the case of a 25 year old patient, with a giant schwannoma which invaded the ischiatic region reaching the triceps surae.
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28549335/microstructural-alterations-of-white-matter-in-juvenile-myoclonic-epilepsy
#2
Jinnan Gong, Xuebin Chang, Sisi Jiang, Benjamin Klugah-Brown, Song Tan, Dezhong Yao, Cheng Luo
Juvenile myoclonic epilepsy (JME) is a common type of idiopathic generalized epilepsy that is characterized by myoclonic jerks of the upper limbs and generalized tonic-clonic seizures. Frontal cognitive dysfunctions and abnormal coupling of the thalamocortical system have been found in neuropsychological and neuroimaging studies. This study intended to explore white matter (WM) measurement changes in JME using MRI. Twenty-six patients with JME and 25 healthy controls (HC) were recruited for the acquisition of diffusion MRI and structural MRI data...
April 4, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28548707/phenotypes-and-genotypes-in-individuals-with-smc1a-variants
#3
Sylvia Huisman, Paul A Mulder, Egbert Redeker, Ingrid Bader, Anne-Marie Bisgaard, Alice Brooks, Anna Cereda, Constanza Cinca, Dinah Clark, Valerie Cormier-Daire, Matthew A Deardorff, Karin Diderich, Mariet Elting, Anthonie van Essen, David Fitz Patrick, Cristina Gervasini, Gabriele Gillessen-Kaesbach, Katta M Girisha, Yvonne Hilhorst-Hofstee, Saskia Hopman, Denise Horn, Mala Isrie, Sandra Jansen, Cathrine Jespersgaard, Frank J Kaiser, Maninder Kaur, Tjitske Kleefstra, Ian D Krantz, Phillis Lakeman, Annemiek Landlust, Davor Lessel, Caroline Michot, Jo Moss, Sarah E Noon, Chris Oliver, Ilaria Parenti, Juan Pie, Feliciano J Ramos, Claudine Rieubland, Silvia Russo, Angelo Selicorni, Zeynep Tümer, Rieneke Vorstenbosch, Tara L Wenger, Ingrid van Balkom, Sigrid Piening, Jolanta Wierzba, Raoul C Hennekam
SMC1A encodes one of the proteins of the cohesin complex. SMC1A variants are known to cause a phenotype resembling Cornelia de Lange syndrome (CdLS). Exome sequencing has allowed recognizing SMC1A variants in individuals with encephalopathy with epilepsy who do not resemble CdLS. We performed an international, interdisciplinary study on 51 individuals with SMC1A variants for physical and behavioral characteristics, and compare results to those in 67 individuals with NIPBL variants. For the Netherlands all known individuals with SMC1A variants were studied, both with and without CdLS phenotype...
May 26, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28546809/comparison-of-brain-activation-during-motor-imagery-and-motor-movement-using-fnirs
#4
Alyssa M Batula, Jesse A Mark, Youngmoo E Kim, Hasan Ayaz
Motor-activity-related mental tasks are widely adopted for brain-computer interfaces (BCIs) as they are a natural extension of movement intention, requiring no training to evoke brain activity. The ideal BCI aims to eliminate neuromuscular movement, making motor imagery tasks, or imagined actions with no muscle movement, good candidates. This study explores cortical activation differences between motor imagery and motor execution for both upper and lower limbs using functional near-infrared spectroscopy (fNIRS)...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28544582/evaluation-by-medical-students-of-the-educational-value-of-multi-material-and-multi-colored-three-dimensional-printed-models-of-the-upper-limb-for-anatomical-education
#5
Sreenivasulu Reddy Mogali, Wai Yee Yeong, Heang Kuan Joel Tan, Gerald Jit Shen Tan, Peter H Abrahams, Nabil Zary, Naomi Low-Beer, Michael Alan Ferenczi
For centuries, cadaveric material has been the cornerstone of anatomical education. For reasons of changes in curriculum emphasis, cost, availability, expertise, and ethical concerns, several medical schools have replaced wet cadaveric specimens with plastinated prosections, plastic models, imaging, and digital models. Discussions about the qualities and limitations of these alternative teaching resources are on-going. We hypothesize that three-dimensional printed (3DP) models can replace or indeed enhance existing resources for anatomical education...
May 19, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28543751/a-pilates-exercise-program-with-pelvic-floor-muscle-contraction-is-it-effective-for-pregnant-women-a-randomized-controlled-trial
#6
Naiara T Dias, Letícia R Ferreira, Mariana G Fernandes, Ana Paula M Resende, Vanessa S Pereira-Baldon
AIMS: The aim of this study was to evaluate the effectiveness of a Pilates exercise program with pelvic floor muscle (PFM) contraction compared to a conventional intervention in pregnant women. METHODS: Fifty primiparous women, without gestational alterations, were randomized to the Pilates group (n = 25) and control group (n = 25). Interventions for both groups consisted of twice-weekly sessions of 1 h each during the period between the 14-16th and 32-34th gestational weeks...
May 23, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28542343/bone-marrow-cell-extract-promotes-the-regeneration-of-irradiated-bone
#7
Guillaume Michel, Pauline Blery, Michaël Henoux, Jérôme Guicheux, Pierre Weiss, Sophie Brouard, Olivier Malard, Florent Espitalier
Mandibular osteoradionecrosis is a severe side effect of radiotherapy after the treatment of squamous cell carcinomas of the upper aerodigestive tract. As an alternative to its treatment by micro-anastomosed free-flaps, preclinical tissular engineering studies have been developed. Total bone marrow (TBM) associated with biphasic calcium phosphate (BCP) significantly enhanced bone formation in irradiated bone. One mechanism, explaining how bone marrow cells can help regenerate tissues like this, is the paracrine effect...
2017: PloS One
https://www.readbyqxmd.com/read/28541374/motor-function-and-incident-dementia-a-systematic-review-and-meta-analysis
#8
Jacqueline Kathleen Kueper, Mark Speechley, Navena Rebecca Lingum, Manuel Montero-Odasso
Background: cognitive and mobility decline are interrelated processes, whereby mobility decline coincides or precedes the onset of cognitive decline. Objective: to assess whether there is an association between performance on motor function tests and incident dementia. Methods: electronic database, grey literature and hand searching identified studies testing for associations between baseline motor function and incident dementia in older adults...
May 25, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28541211/cortical-brain-computer-interface-for-closed-loop-deep-brain-stimulation
#9
Jeffrey Herron, Margaret Thompson, Tim Brown, Howard Chizeck, Jeffrey Ojemann, Andrew Ko
Essential Tremor is the most common neurological movement disorder. This progressive disease causes uncontrollable rhythmic motions-most often affecting the patient's dominant upper extremity-that occur during volitional movement and make it difficult for the patient to perform everyday tasks. Medication may also become ineffective as the disorder progresses. For many patients, deep brain stimulation (DBS) of the thalamus is an effective means of treating this condition when medication fails. In current use, however, clinicians set the patient's stimulator to apply stimulation at all times-whether it is needed or not...
May 18, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28540536/effects-of-robot-assisted-upper-limb-rehabilitation-in-stroke-patients-a-systematic-review-with-meta-analysis
#10
Rachele Bertani, Corrado Melegari, Maria C De Cola, Alessia Bramanti, Placido Bramanti, Rocco Salvatore Calabrò
Technology-supported training is emerging as a solution to support therapists in their efforts providing high-intensity, repetitive, and task-specific treatment, in order to enhance the recovery process. The aim of this review is to assess the effectiveness of different robotic devices (end-effector and exoskeleton robots) in comparison with any other type of intervention. Furthermore, we aim to assess whether or not better improvements are obtained in the sub-acute phase after stroke onset than in the chronic phase...
May 24, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28540415/incidence-of-osteosynthesis-of-members-in-france
#11
Patrice Papin, Eric Berthonnaud
PURPOSE: Little data is available on the number of osteosynthesis of limbs in a country. Incidence of osteosynthesis is an essential element for the formation and organization of care. Based on the data from the work of the Hospital Information Technology Agency ( http://www.atih.sante.fr/ ) and available in open access, we wanted to know the incidence of the number of osteosynthesis performed in France and their evolution over ten years between 2006 and 2015. METHODS: The data analyzed are derived from the website of the technical agency of information on the hospitalization (ATIH)...
May 24, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28540122/presurgical-role-of-mri-tractography-in-a-case-of-extensive-cervicothoracic-spinal-ependymoma
#12
Francesca Granata, Sergio Racchiusa, Enricomaria Mormina, Valeria Barresi, Giada Garufi, Giovanni Grasso, Francesco Maria Salpietro, Marcello Longo, Concetta Alafaci
BACKGROUND: Intramedullary spinal ependymoma is a tumor, hardly characterizable with conventional magnetic resonance (MR) imaging only. MR diffusion tensor imaging (DTI) with three-dimensional fiber-tracking reconstructions allows the evaluation of the relationship between neoplasm and white matter fiber tracts, being a powerful tool in presurgical planning. We present DTI findings in a case of a young female with an extensive cervicothoracic spinal ependymoma. CASE DESCRIPTION: The patient complained of a 2-month history of acute urinary retention, weakness and numbness on the lower limbs and the upper left limb...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28539911/the-use-of-functional-electrical-stimulation-on-the-upper-limb-and-interscapular-muscles-of-patients-with-stroke-for-the-improvement-of-reaching-movements-a-feasibility-study
#13
Alicia Cuesta-Gómez, Francisco Molina-Rueda, Maria Carratala-Tejada, Eukene Imatz-Ojanguren, Diego Torricelli, Juan Carlos Miangolarra-Page
INTRODUCTION: Reaching movements in stroke patients are characterized by decreased amplitudes at the shoulder and elbow joints and greater displacements of the trunk, compared to healthy subjects. The importance of an appropriate and specific contraction of the interscapular and upper limb (UL) muscles is crucial to achieving proper reaching movements. Functional electrical stimulation (FES) is used to activate the paretic muscles using short-duration electrical pulses. OBJECTIVE: To evaluate whether the application of FES in the UL and interscapular muscles of stroke patients with motor impairments of the UL modifies patients' reaching patterns, measured using instrumental movement analysis systems...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28539691/goals-set-by-patients-using-the-icf-model-before-receiving-botulinum-injections-and-their-relation-to-spasticity-distribution
#14
Kevin Choi, Jaclyn Peters, Andrew Tri, Elizabeth Chapman, Ayako Sasaki, Farooq Ismail, Chris Boulias, Shannon Reid, Chetan P Phadke
Purpose: Goal Attainment Scaling (GAS) is used to assess functional gains in response to treatment. Specific characteristics of the functional goals set by individuals receiving botulinum toxin type A (BoNTA) injections for spasticity management are unknown. The primary objectives of this study were to describe the characteristics of the goals set by patients before receiving BoNTA injections using the International Classification of Functioning, Disability and Health (ICF) and to determine whether the pattern of spasticity distribution affected the goals set...
2017: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/28539669/sensorimotor-adaptation-as-a-behavioural-biomarker-of-early-spinocerebellar-ataxia-type-6
#15
Muriel T N Panouillères, Raed A Joundi, Sonia Benitez-Riveiro, Binith Cheeran, Christopher R Butler, Andrea H Németh, R Chris Miall, Ned Jenkinson
Early detection of the behavioural deficits of neurodegenerative diseases may help to describe the pathogenesis of such diseases and establish important biomarkers of disease progression. The aim of this study was to identify how sensorimotor adaptation of the upper limb, a cerebellar-dependent process restoring movement accuracy after introduction of a perturbation, is affected at the pre-clinical and clinical stages of spinocerebellar ataxia type 6 (SCA6), an inherited neurodegenerative disease. We demonstrate that initial adaptation to the perturbation was significantly impaired in the eighteen individuals with clinical motor symptoms but mostly preserved in the five pre-clinical individuals...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28539399/using-theoretical-models-from-adult-stroke-recovery-to-improve-use-of-non-invasive-brain-stimulation-for-children-with-congenital-hemiparesis
#16
Yin-Liang Lin, Kelsey A Potter-Baker
Non-invasive brain stimulation has been widely used for adults with stroke to improve upper limb motor function. A recent study by Kirton and colleagues (Kirton A, Ciechanski P, Zewdie E et al. Neurology 2017, doi: 10.1212/WNL.0000000000003518) applied non-invasive brain stimulation to children with congenital hemiparesis but found no significant effect of non-invasive brain stimulation on motor function. Here, we explore theories about cortical reorganization in both adult and children with hemiparesis and discuss how to improve the approaches of non-invasive brain stimulation to generate optimal motor improvement and development for children with congenital hemiparesis...
May 24, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28538894/sweet-s-syndrome-associated-with-crohn-s-disease
#17
Caren Dos Santos Lima, Roberta Duarte Bezerra Pinto, Heliana Freitas de Oliveira Góes, Simone de Abreu Neves Salles, Enoi Aparecida Guedes Vilar, Carla Dos Santos Lima
Sweet's syndrome is an uncommon benign skin disorder, whose pathogenesis remains unknown. Its classic form is more common in women and presents itself as papular-nodular, painful and erythematous or violaceous lesions. It mainly affects the face, neck, and upper limbs. Fever and neutrophilic leukocytosis are also common features. Although it is considered a systemic disease marker in more than half of patients, the association of this condition with Crohn's disease is rare, with few cases reported in the literature, of which, none in Brazil...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538571/angiosome-based-allografts-vascularized-composite-allotransplantation-for-tailored-subunit-reconstruction-with-volkmann-ischemic-contracture-as-a-case-in-point
#18
G Ian Taylor, David S Sparks, Adam C Gascoigne, Russell J Corlett, Mark W Ashton
BACKGROUND: As we enter an age with new approaches to tissue reconstruction, the emphasis on the adage "like for like" has become even more relevant. This study illustrates the potential for several tailored vascularized composite allotransplantation reconstructive techniques and, in particular, for the management of Volkmann contracture. METHODS: Twenty fresh cadaver dissections and 30 archival lead oxide radiographic studies were examined to (1) identify potential upper limb vascularized composite allotransplantation donor sites (i...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538303/examining-fundamental-movement-competency-and-closed-chain-upper-extremity-dynamic-balance-in-swimmers
#19
Garrett S Bullock, Nate Brookreson, Amy M Knab, Robert J Butler
Bullock, GS, Brookreson, N, Knab, AM, and Butler, RJ. Examining fundamental movement competency and closed-chain upper-extremity dynamic balance in swimmers. J Strength Cond Res 31(6): 1544-1551, 2017-Abnormal fundamental movement patterns and upper-quarter dynamic balance are proposed mechanisms affecting athletic performance and injury risk. There are few studies investigating functional movement and closed-chain upper-extremity dynamic stability in swimmers. The purpose of this study was to determine differences in fundamental movement competency and closed-chain upper-extremity dynamic balance, using the Functional Movement Screen (FMS) and Upper-Quarter Y Balance Test (YBT-UQ), of high school (HS; n = 70) and collegiate (COL; n = 70) swimmers...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538051/mobius-syndrome-a-35-year-single-institution-experience
#20
Philip K McClure, Eray Kilinc, Scott Oishi, Anthony I Riccio, Lori A Karol
BACKGROUND: Mobius syndrome is a rare syndrome that is known to be associated with a variety of orthopaedic conditions including scoliosis, clubfoot, transverse limb deficiencies, Poland syndrome, and a myriad of hand conditions. To date, no large series exist to characterize the orthopaedic manifestations of Mobius syndrome. METHODS: Medical records at a single tertiary pediatric institution were reviewed for all patients diagnosed with Mobius syndrome from January 1, 1980 to December 31, 2015...
May 19, 2017: Journal of Pediatric Orthopedics
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