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Functional muscle transfer

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https://www.readbyqxmd.com/read/28822637/porcine-dermis-patch-augmentation-of-supraspinatus-tendon-repairs-a-pilot-study-assessing-tendon-integrity-and-shoulder-function-2%C3%A2-years-after-arthroscopic-repair-in-patients-aged-60%C3%A2-years-or%C3%A2-older
#1
Matthias Flury, Dominik Rickenbacher, Christian Jung, Marco M Schneider, David Endell, Laurent Audigé
PURPOSE: To investigate the 2-year postoperative clinical and subjective outcomes after arthroscopic rotator cuff repair (ARCR) with xenologous porcine dermal patch augmentation compared with ARCR alone. METHODS: Patients aged 60 years or older with a complete supraspinatus (SSP) tendon tear underwent primary ARCR with a transosseous-equivalent technique. By use of a matched-pair comparative trial design, a consecutive series of 20 patients receiving additional xenologous porcine dermal patch augmentation (patch group) was matched by tear location with 20 patients who received ARCR only (control group)...
August 16, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28820842/-upper-extremity-innervation-patterns-and-clinical-implications-for-nerve-and-tendon-transfer
#2
Ellen Y Lee, Sandeep J Sebastin, Andre Cheah, V P Kumar, Aymeric Y T Lim
BACKGROUND: We previously studied the intramuscular innervation of 150 upper limb muscles and demonstrated that certain patterns of intramuscular innervation allowed muscles to be split into compartments with independent function. This study aims to determine the location, extra-muscular course, and number of motor nerve branches of upper limb peripheral nerves. We want to combine this information with our previous work to create a blueprint of upper limb neuromuscular anatomy that would be useful in reconstructive surgery...
August 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28813989/quantification-of-information-transfer-rate-of-the-human-hand-during-a-mouse-clicking-task-with-healthy-adults-and-one-adult-with-duchenne-muscular-dystrophy
#3
Kostas Nizamis, Wouter Schutte, Jasper Goseling, Bart F J M Koopman
Duchenne muscular Dystrophy (DMD) Is a progressive muscle degenerative disease. Active hand assistive devices, can improve the quality of life of people with DMD. Such devices show a rejection rate due to complexity. Our hypothesis is, that a simple orthosis might prove more functional and realistic in assisting people with DMD. To investigate, we developed a portable setup that provides various visual stimuli and records the response of the subjects' fingers through a mouse clicking task. Six LEDs served as visual stimuli...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28808593/combined-bone-transportation-and-lengthening-techniques-for-the-treatment-of-septic-nonunion-of-the-forearm-followed-by-tendon-transfer
#4
Konstantinos Ditsios, Eirini Iosifidou, Lazaros Kostretzis, Panagiotis Konstantinou, Iosafat Pinto, Ioannis Theodoroudis, Ippokratis Hatzokos
Infected nonunion of a forearm fracture complicated by a considerable skin-muscle defect poses a great challenge to orthopaedic surgeons. The treatment strategy comprises eradication of the infection, ensuring bony union and soft tissue coverage along with functional restoration. We report a case of a 23-year-old man with an open Gustilo-Anderson IIIb fracture complicated by infected nonunion after internal fixation. After thorough surgical debridement, a considerable soft tissue defect, extensor muscle loss, and posterior interosseous nerve laceration had to be addressed...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28777228/the-disputed-discovery-of-facial-and-trigeminal-nerve-function-revisiting-the-contributions-of-herbert-mayo-and-charles-bell
#5
Matthew L Carlson, James Bradley, Jamie J Van Gompel, R Shane Tubbs
BACKGROUND: The first description of the voluntary motor function of the facial nerve and separate sensory-motor contributions of the trigeminal nerve is most commonly attributed to Charles Bell. However, a review of the original scientific accounts and subsequent historical publications question the validity of this credit. The objective of the present historical analysis is to clarify the contributions of Herbert Mayo toward discovering the functions of the fifth and seventh cranial nerves and to raise awareness of this historical controversy within the medical literature...
August 2, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28774248/thumb-function-and-electromyography-result-after-modified-camitz-tendon-transfer
#6
Claire Marie Durban, Bernard Antolin, Chung Ying Sau, Sheung Wai Li, Wing Yuk Ip
BACKGROUND: Various techniques of opponensplasty have been developed with the aim of restoring the thumb function. The modified Camitz opponensplasty is a simple technique done together with an open carpal tunnel release. It restores thumb palmar abduction soon after the procedure, during such time that the abductor pollicis brevis (APB) is still recovering. The aim of this study was to assess the recovery and level of activity of the abductor pollicis brevis and palmaris longus (PL) muscles during thumb opposition and abduction after performing the modified Camitz opponensplasty...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28774242/adductor-tenotomy-combined-with-palmar-capsulodesis-for-spastic-thumb-in-palm-deformity-in-cerebral-palsy-description-of-a-surgical-technique-and-clinical-results
#7
García Luis-Alejandro, Gómez Bárbara
BACKGROUND: Spastic thumb deformity in cerebral palsy significantly impedes hand function. Flexion-adduction forces across the first ray is the result from imbalance between intrinsic and extrinsic muscles. Multiples surgeries have been devised for the treatment of this condition such as contracture release and by tendon transfers for balancing the muscles forces. We report the results of a less demanding surgical technique, intended to avoid hyperextension of the metacarpophalangeal joint previously described in other series...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28769755/broadband-prosthetic-interfaces-combining-nerve-transfers-and-implantable-multichannel-emg-technology-to-decode-spinal-motor-neuron-activity
#8
Konstantin D Bergmeister, Ivan Vujaklija, Silvia Muceli, Agnes Sturma, Laura A Hruby, Cosima Prahm, Otto Riedl, Stefan Salminger, Krisztina Manzano-Szalai, Martin Aman, Michael-Friedrich Russold, Christian Hofer, Jose Principe, Dario Farina, Oskar C Aszmann
Modern robotic hands/upper limbs may replace multiple degrees of freedom of extremity function. However, their intuitive use requires a high number of control signals, which current man-machine interfaces do not provide. Here, we discuss a broadband control interface that combines targeted muscle reinnervation, implantable multichannel electromyographic sensors, and advanced decoding to address the increasing capabilities of modern robotic limbs. With targeted muscle reinnervation, nerves that have lost their targets due to an amputation are surgically transferred to residual stump muscles to increase the number of intuitive prosthetic control signals...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28755158/optimizing-endothelial-cell-functionalization-for-cell-therapy-of-vascular-proliferative-disease-using-a-direct-contact-co-culture-system
#9
Mark R Battig, Ilia Fishbein, Robert J Levy, Ivan S Alferiev, David Guerrero, Michael Chorny
Increased susceptibility to thrombosis, neoatherosclerosis, and restenosis due to incomplete regrowth of the protective endothelial layer remains a critical limitation of the interventional strategies currently used clinically to relieve atherosclerotic obstruction. Rapid recovery of endothelium holds promise for both preventing the thrombotic events and reducing post-angioplasty restenosis, providing the rationale for developing cell delivery strategies for accelerating arterial reendothelialization. The successful translation of experimental cell therapies into clinically viable treatment modalities for restoring vascular endothelium critically depends on identifying strategies for enhancing the functionality of endothelial cells (EC) derived from high cardiovascular risk patients, the target group for the majority of angioplasty procedures...
July 28, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28750798/functional-pectoralis-minor-myocutaneous-flap-transplantation-for-reconstruction-of-thumb-opposition-an-anatomic-study-with-clinical-applications
#10
Yong-Qing Zhuang, Hong-Tao Xiong, Qiang Fu, Xuan Zhang, Hao-Li Jiang, Xi-Chi Fang
OBJECTIVE: To develop a myocutaneous flap for reconstruction of thumb opposition function in patients with loss of the thenar muscles and skin. METHODS: An anatomic experiment on the dimensions of the pectoralis minor muscle and its neurovascular supply in 10 adult human cadavers was conducted to evaluate the feasibility of microsurgical transplantation using part of the muscle for thumb opposition reconstruction. Based on these results, we performed surgical thenar reconstruction with a pectoralis minor myocutaneous flap in seven patients (34...
July 24, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28746282/outcomes-of-muscle-brachialis-transfer-to-restore-finger-flexion-in-brachial-plexus-palsy
#11
Brent R DeGeorge, Hillary A Becker, John H Faryna, Robert J Spinner, Allen T Bishop, Alexander Y Shin
BACKGROUND: In adults with lower trunk brachial plexus injury, proximal nerve surgery for restoration of prehension demonstrates poor outcomes secondary to long distances required for nerve regeneration and time-dependent degradation of motor endplates. Options for reconstruction are limited to distal tendon or nerve transfers and free-functioning muscle transfers. In this article, the authors describe the long-term outcomes of brachialis muscle-to-flexor digitorum profundus transfer to restore prehension in patients with traumatic lower trunk brachial plexus injuries...
August 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28746244/the-effect-of-unicycle-riding-course-on-trunk-strength-and-trunk-stability-functions-in-children
#12
Andrej Kocjan, Nejc Sarabon
PURPOSE: The aim of the study was to assess the effect of unicycling on trunk strength and timing of automatic stability actions of the selected trunk muscles (multifidus, obliquus externus, erector spine). METHODS: Twenty healthy 12-year-old children (12 boys, 8 girls; age 12.1 ± 0.2 yrs; body height 1.57 ± 0.05 m; body mass 52.8 ± 10.6 kg) were assigned to experimental and control group. Experimental group performed a supervised 12-session course of unicycling...
July 24, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28721468/are-animal-models-predictive-for-human-postmortem-muscle-protein-degradation
#13
Bianca Ehrenfellner, Angela Zissler, Peter Steinbacher, Fabio C Monticelli, Stefan Pittner
A most precise determination of the postmortem interval (PMI) is a crucial aspect in forensic casework. Although there are diverse approaches available to date, the high heterogeneity of cases together with the respective postmortal changes often limit the validity and sufficiency of many methods. Recently, a novel approach for time since death estimation by the analysis of postmortal changes of muscle proteins was proposed. It is however necessary to improve the reliability and accuracy, especially by analysis of possible influencing factors on protein degradation...
July 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28718780/biarticular-elements-as-a-contributor-to-energy-efficiency-biomechanical-review-and-application-in-bio-inspired-robotics
#14
Karen Junius, Marta Moltedo, Pierre Cherelle, Carlos David Rodriguez-Guerrero, Bram Vanderborght, Dirk Lefeber
Despite the increased interest in exoskeleton research in the last decades, not much progress has been made on the successful reduction of user effort. In humans, biarticular elements have been identied as one of the reasons for the energy economy of locomotion. This document gives an extensive literature overview concerning the function of biarticular mus- cles in human beings. The exact role of these muscles in the efficiency of human locomotion is reduced to three elementary functions: energy transfer towards distal joints, efficient control of output force direction and double joint actuation...
July 18, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28708000/reactive-oxygen-species-and-mitochondrial-homeostasis-as-regulators-of-stem-cell-fate-and-function
#15
Darren Qiancheng Tan, Toshio Suda
SIGNIFICANCE: The precise role and impact of reactive oxygen species (ROS) in stem cells, which are essential for lifelong tissue homeostasis and regeneration, remains of significant interest to the field. The long-term regenerative potential of a stem cell compartment is determined by the delicate balance between quiescence, self-renewal and differentiation; all of which can be influenced by ROS levels. Recent advances: The past decade has seen a growing appreciation for the importance of ROS and redox homeostasis in various stem cell compartments; particularly those of hematopoietic, neural and muscle tissues...
July 14, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28691601/task-specific-and-functional-effects-of-speed-focused-elliptical-or-motor-assisted-cycle-training-in-children-with-bilateral-cerebral-palsy-randomized-clinical-trial
#16
Diane L Damiano, Christopher J Stanley, Laurie Ohlrich, Katharine E Alter
BACKGROUND: Locomotor training using treadmills or robotic devices is commonly utilized to improve gait in cerebral palsy (CP); however, effects are inconsistent and fail to exceed those of equally intense alternatives. Possible limitations of existing devices include fixed nonvariable rhythm and too much limb or body weight assistance. OBJECTIVE: To quantify and compare effectiveness of a motor-assisted cycle and a novel alternative, an elliptical, in CP to improve interlimb reciprocal coordination through intensive speed-focused leg training...
July 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28689830/is-bipolar-latissimus-dorsi-transfer-a-reliable-option-to-restore-elbow-flexion-in-children-with-arthrogryposis-a-review-of-13-tendon-transfers
#17
Ramin Zargarbashi, Mohammad Hossein Nabian, Jean-David Werthel, Philippe Valenti
BACKGROUND: Scant data are published about different available therapeutic options for restoration of active elbow flexion in arthrogryposis with varying degrees of improvement. In this retrospective study we evaluated medium-term effects of bipolar latissimus dorsi transfer in patients with arthrogryposis. METHODS: Pedicled latissimus dorsi bipolar muscle transfer was used to restore elbow flexion in 11 patients (13 limbs) with arthrogryposis. Elbow and shoulder range of motions and strength of elbow flexion were measured preoperatively and at the last follow-up...
July 6, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28684374/investigating-crispr-cas-systems-in-clostridium-botulinum-via-bioinformatics-tools
#18
Manica Negahdaripour, Navid Nezafat, Nasim Hajighahramani, Seyyed Soheil Rahmatabadi, Younes Ghasemi
The Clustered regularly interspaced short palindromic repeats (CRISPR) systems are a type of innate immunity found in some prokaryotes, which protect them against alien genetic elements by targeting foreign nucleic acids. Some other functions are also attributed to these systems. Clostridium botulinum bacteria produce botulinum neurotoxins (BoNT), one of the deadliest known toxins for humans and some animals. Food poisoning due to these bacteria is still a challenge in food industries. On the other hand, BoNT has been widely investigated for therapeutic applications including different muscle disorders...
July 4, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28678067/reconstruction-of-parotidectomy-and-lateral-skull-base-defects
#19
Caitlin Bertelsen, Changxing Liu, Niels Kokot
PURPOSE OF REVIEW: The purpose of this review is to summarize the options for reconstruction of parotid and lateral skull base defects based on the size and functional requirements of the defect. RECENT FINDINGS: Free grafts with dermal fat or acellular human dermis, superficial musculoaponeurotic system flaps, and sternocleidomastoid flaps have been successful in preventing Frey's syndrome and restoring facial contour defects after superficial and total parotidectomy...
July 3, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28676167/reconstruction-of-mohs-defects-of-the-lips-and-chin
#20
REVIEW
Yuna C Larrabee, Jeffrey S Moyer
Reconstruction of defects of the lips after Mohs micrographic surgery should encompass functional and aesthetic concerns. The lower lip and chin compose two-thirds of the lower portion of the face. The focus of this article is local tissue transfer for primarily cutaneous defects after Mohs surgery. Various flaps exist for repair. For small defects, elliptical excision with primary closure is a viable option. During reconstruction of the lip, all of the involved layers need to be addressed, including mucosa, muscle, and the vermillion or cutaneous lip...
August 2017: Facial Plastic Surgery Clinics of North America
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