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Functional muscle transfer

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https://www.readbyqxmd.com/read/28086945/complete-deltoid-resection-in-early-childhood-without-muscle-transfer-results-in-normal-shoulder-function-at-long-term-follow-up-a-case-report
#1
Annie Arteau, Franziska Seeli, Bruno Fuchs
BACKGROUND: Musculoskeletal tumors involving the deltoid muscle and necessitating its complete resection are rare. The function after complete deltoid resection is reported to be limited, and several authors consider muscle transfer to improve shoulder motion. However, it still remains unclear whether such transfer adds function. To the best of our knowledge, all reports on complete deltoid resection refer to adult patients, and it is unknown what function results after deltoid resection in childhood...
January 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28052417/c8-cross-transfer-for-the-treatment-of-caudal-brachial-plexus-avulsion-in-three-dogs
#2
Pierre Moissonnier, Claude Carozzo, Jean-Laurent Thibaut, Catherine Escriou, Antoine Hidalgo, Stéphane Blot
OBJECTIVE: To evaluate the cervical nerve 8 cross-transfer technique (C8CT) as a part of surgical treatment of caudal brachial plexus avulsion (BPA) in the dog. STUDY DESIGN: Case series. ANIMALS: Client-owned dogs suspected to have caudal BPA based on neurological examination and electrophysiological testing (n = 3). METHODS: The distal stump of the surgically transected contralateral C8 ventral branch (donor) was bridged to the proximal stump of the avulsed C8 ventral branch (recipient) and secured with 9-0 polypropylene suture under an operating microscope...
January 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28039026/unraveling-proteome-changes-of-holstein-beef-m-semitendinosus-and-its-relationship-to-meat-discoloration-during-post-mortem-storage-analyzed-by-label-free-mass-spectrometry
#3
Qianqian Yu, Wei Wu, Xiaojing Tian, Man Hou, Ruitong Dai, Xingmin Li
: Label-free proteomics was applied to characterize the effect of post-mortem storage time (0, 4, and 9days at 4°C±1°C) on the proteome changes of M. semitendinosus (SM) in Holstein cattle, and correlations between differentially abundant proteins and meat color traits were investigated. The redness (a*) value decreased significantly (P<0.05) during post-mortem storage, meanwhile, the relative proportion of metmyoglobin increased significantly (P<0.05) from 16.99% at day 0 to 40...
December 28, 2016: Journal of Proteomics
https://www.readbyqxmd.com/read/28031243/caenorhabditis-elegans-male-copulation-circuitry-incorporates-sex-shared-defecation-components-to-promote-intromission-and-sperm-transfer
#4
Brigitte LeBoeuf, L Rene Garcia
Sexual dimorphism can be achieved using a variety of mechanisms, including sex-specific circuits and sex-specific function of shared circuits, though how these work together to produce sexually dimorphic behaviors require further investigation. Here, we explore how components of the sex-shared defecation circuitry are incorporated into the sex-specific male mating circuitry in Caenorhabditis elegans to produce successful copulation. Using behavioral studies, calcium imaging, and genetic manipulation, we show that aspects of the defecation system are co-opted by the male copulatory circuitry to facilitate intromission and ejaculation...
December 27, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28029602/use-of-both-antegrade-and-retrograde-internal-mammary-vessels-in-the-bipedicled-deep-inferior-epigastric-perforator-flap-for-unilateral-breast-reconstruction
#5
Jonatan Hernandez Rosa, Rami D Sherif, Philip J Torina, Marco A Harmaty
BACKGROUND: Autologous abdominal tissue transfer is a well-established method of breast reconstruction. The deep inferior epigastric perforator (DIEP) flap has the additional benefit of minimal donor site morbidity as it spares the muscle and fascia. Conventional DIEP flaps may not provide adequate volume in cases where the patient is thin, has midline abdominal scars, and/or has a large volume of tissue to replace. One solution is to use a bipedicled DIEP flap, incorporating all the available abdominal tissue...
September 20, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28027238/free-functioning-gracilis-muscle-transfer-for-elbow-flexion-reconstruction-after-traumatic-adult-brachial-pan-plexus-injury-where-is-the-optimal-distal-tendon-attachment-for-elbow-flexion
#6
Andrés A Maldonado, Santiago Romero-Brufau, Michelle F Kircher, Robert J Spinner, Allen T Bishop, Alexander Y Shin
BACKGROUND: Reconstruction after pan-plexus root avulsions often includes gracilis free functioning muscle transfer. For elbow flexion reconstruction, the free functioning muscle transfer distal tendon is inserted into the biceps tendon or more distally (i.e., flexor digitorum profundus/flexor pollicis longus tendons) for combined elbow and finger flexion; the theoretical drawback of the latter approach is weaker elbow flexion. The authors compared elbow flexion strength with a biceps tendon versus a flexor digitorum profundus/flexor pollicis longus tendon attachment to determine which insertion point resulted in better elbow flexion...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28027234/selective-nerve-root-transection-in-the-rat-produces-permanent-partial-nerve-injury-models-with-variable-levels-of-functional-deficit
#7
Louis H Poppler, Lauren M Schellhardt, Daniel A Hunter, Ying Yan, Susan E Mackinnon, Matthew D Wood, Amy M Moore
BACKGROUND: The goal of this study was to develop a partial, nonregenerative nerve injury model in a rat that results in permanently reduced motoneuron numbers and function. This model could serve as a platform for the study of therapeutics, such as a reverse end-to-side nerve transfer (i.e., supercharge). The authors hypothesized that transection of one or more of the L4 to L6 nerve roots supplying the sciatic nerve would cause a permanent reduction in muscle force. METHODS: Rats were randomized into five groups that underwent variations of nerve root transections or sham injury...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28005165/free-lateral-tarsal-artery-perforator-flap-with-functioning-extensor-digitorum-brevis-muscle-for-thenar-reconstruction-a-case-report
#8
Tianliang Wang, Subhash Regmi, Hongjun Liu, Junbo Pan, Ruixing Hou
In this case report, we describe reconstructive surgery in one patient using a free lateral tarsal artery perforator flap with a functioning extensor digitorum brevis muscle. A 47-year-old woman sustained a crush-avulsion injury to her dominant right hand while working in a factory. A large thenar skin and muscle defect (5.5 cm × 4.0 cm) occurred as a consequence of surgical debridement. The skin and muscle defect was repaired using a free lateral tarsal artery perforator flap with a functioning extensor digitorum brevis muscle in a single operation...
December 22, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27993833/nkx2-5-is-expressed-in-atherosclerotic-plaques-and-attenuates-development-of-atherosclerosis-in-apolipoprotein-e-deficient-mice
#9
Meng Du, Xiaojing Wang, Xin Tan, Xiangrao Li, Dandan Huang, Kun Huang, Liu Yang, Fengxiao Zhang, Yan Wang, Dan Huang, Kai Huang
BACKGROUND: NK2 homeobox 5 (Nkx2-5) is a cardiac homeobox transcription factor that is expressed in a broad range of cardiac sublineages. Embryos lacking Nkx2-5 are nonviable attributed to growth retardation and gross abnormalities of the heart. However, the role of Nkx2-5 in atherosclerosis remains elusive. This study aims to elucidate the specific functions of Nkx2-5 during atherogenesis and in established atherosclerotic plaques. METHODS AND RESULTS: Two types of atherosclerotic lesions were created in ApoE(-/-) mice through 2 different dietary manipulations...
December 19, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27993587/percutaneous-needle-tenotomy-for-the-treatment-of-muscle-and-tendon-contractures-in-adults-with-brain-damage-results-and-complications
#10
Flavia Coroian, Claire Jourdan, Jérome Froger, Claire Anquetil, Olivier Choquet, Bertand Coulet, Isabelle Laffont
OBJECTIVE: To study the results and complications of percutaneous needle tenotomy (PNT) of superficial retracted tendons in brain damaged patients. Muscle and tendon contractures are common in this population and can lead to severe functional impairment. Care management is commonly based on open surgical tenotomy. PNT is a mini-invasive surgical procedure suspected to be safer among frail patients. DESIGN: Prospective observational study SETTING: University Hospital Physical Medicine and Rehabilitation (PM&R) and Orthopedic Surgery Departments...
December 16, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27988149/a-technique-for-facial-reanimation-the-partial-temporalis-muscle-tendon-transfer-with-a-fascia-lata-sling
#11
Thomas Edward Pidgeon, Radovan Boca, Fazel Fatah
BACKGROUND: This report describes the results of a surgical procedure for facial reanimation. This single-stage technique involves the orthodromic transfer of only a superficial segment of the temporalis tendon. This is extended with fascia lata to achieve elevation of the oral commissure along the desired vector in the paralysed hemi-face. METHODS: A retrospective case note review was performed. Patients' photographs were objectively evaluated with Facial Assessment by Computer Evaluation (FACE) software...
November 10, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27984219/one-stage-aesthetic-and-functional-reconstruction-of-major-lower-lip-defects
#12
Nader Elmelegy, Dalia Mohamed Mofreh El Sakka
INTRODUCTION: Multiple techniques have been used for reconstruction of large defects of the lower lip. However, some complications, such as microstomia, distortion of oral commissure, lip functional problems, and sensory loss might occur with these techniques. The aim of this work is to evaluate a new method of reconstruction of large lower lip defects after excision of squamous cell carcinoma. PATIENTS AND METHODS: Eighteen patients with lower lip squamous cell carcinomas were managed with this new technique of reconstruction using dermal fat flap, mucobuccal flap, and muscle transfer after excision of the tumor with 1-cm safety margin on both sides...
December 14, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27976451/arteriogenesis-in-murine-adipose-tissue-is-contingent-on-cd68-cd206-macrophages
#13
Scott A Seaman, Yiqi Cao, Chris A Campbell, Shayn M Peirce
OBJECTIVE: The surgical transfer of skin, fat, and/or muscle from a donor site to a recipient site within the same patient, is a widely performed procedure in reconstructive surgeries. A surgical pre-treatment strategy that is intended to increase perfusion in the flap, termed "flap delay", is a commonly employed technique by plastic surgeons prior to flap transplantation. Here, we explored whether CD68(+) /CD206(+) macrophages are required for arteriogenesis within the flap by performing gain-of-function and loss-of-function studies in a previously published flap delay murine model...
December 15, 2016: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/27932695/posture-dependent-corticomotor-excitability-differs-between-the-transferred-biceps-in-individuals-with-tetraplegia-and-the-biceps-of-nonimpaired-individuals
#14
Carrie L Peterson, Lynn M Rogers, Michael S Bednar, Anne M Bryden, Michael W Keith, Eric J Perreault, Wendy M Murray
Background Following biceps transfer to enable elbow extension in individuals with tetraplegia, motor re-education may be facilitated by greater corticomotor excitability. Arm posture modulates corticomotor excitability of the nonimpaired biceps. If arm posture also modulates excitability of the transferred biceps, posture may aid in motor re-education. Objective Our objective was to determine whether multi-joint arm posture affects corticomotor excitability of the transferred biceps similar to the nonimpaired biceps...
December 8, 2016: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/27927653/knockdown-of-add3-impairs-the-myogenic-response-of-renal-afferent-arterioles-and-middle-cerebral-arteries
#15
Fan Fan, Mallikarjuna R Pabbidi, Ying Ge, Longyang Li, Shaoxun Wang, Paige N Mims, Richard J Roman
We have reported that the myogenic response of the renal afferent arteriole (Af-art) and middle cerebral artery (MCA), and autoregulation of renal and cerebral blood flow are impaired in Fawn Hood Hypertensive (FHH) rats. Transfer of a region of chromosome 1 containing gamma-adducin (Add3) from Brown Norway rats rescues the vascular dysfunction and the development of renal disease. To examine whether Add3 is a viable candidate gene altering renal and cerebral hemodynamics in FHH rats, we knocked down the expression of Add3 in rat Af-art and MCA cultured for 36-hours using a 27-mer Dicer-substrate short interfering RNA (DsiRNA)...
December 7, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/27918667/neuromuscular-fatigue-aetiology-after-repeated-sprints-depends-on-exercise-modality
#16
Katja Tomazin, Jean-Benoit Morin, Guillaume Y Millet
PURPOSE: The aim of the study was to compare neuromuscular fatigue induced by repeated sprint running vs cycling. METHODS: Eleven active male participants performed two repeated maximal sprint protocol (5×6 s, 24-s rest periods, 4 sets, 3-min between sets), one in running (treadmill) and one in cycling (cycle ergometer). Neuromuscular function, evaluated before (PRE), 30 s after the first (S1), the second (S2), and the last set (LAST), and 5 min after the last set (POST5), consisted in determining knee extensors maximal voluntary torque (MVC), voluntary activation (VA), single twitch (Tw), high- (Db100) and low- (Db10) frequency torque, and maximal muscle compound action potential (M-wave) amplitude and duration of vastus lateralis...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27911944/specific-stimuli-induce-specific-adaptations-sensorimotor-training-vs-reactive-balance-training
#17
Kathrin Freyler, Anne Krause, Albert Gollhofer, Ramona Ritzmann
Typically, balance training has been used as an intervention paradigm either as static or as reactive balance training. Possible differences in functional outcomes between the two modalities have not been profoundly studied. The objective of the study was to investigate the specificity of neuromuscular adaptations in response to two balance intervention modalities within test and intervention paradigms containing characteristics of both profiles: classical sensorimotor training (SMT) referring to a static ledger pivoting around the ankle joint vs...
2016: PloS One
https://www.readbyqxmd.com/read/27909699/aav-mediated-sirt1-overexpression-in-skeletal-muscle-activates-oxidative-capacity-but-does-not-prevent-insulin-resistance
#18
Laia Vilà, Carles Roca, Ivet Elias, Alba Casellas, Ricardo Lage, Sylvie Franckhauser, Fatima Bosch
Type 2 diabetes is characterized by triglyceride accumulation and reduced lipid oxidation capacity in skeletal muscle. SIRT1 is a key protein in the regulation of lipid oxidation and its expression is reduced in the skeletal muscle of insulin resistant mice. In this tissue, Sirt1 up-regulates the expression of genes involved in oxidative metabolism and improves mitochondrial function mainly through PPARGC1 deacetylation. Here we examined whether Sirt1 overexpression mediated by adeno-associated viral vectors of serotype 1 (AAV1) specifically in skeletal muscle can counteract the development of insulin resistance induced by a high fat diet in mice...
2016: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/27900313/semitendinosus-and-gracilis-free-muscle-tendon-graft-for-repair-of-massive-rotator-cuff-tears-surgical-technique
#19
Antonio Gigante, Carlo Bottegoni, Giuseppe Milano, Michele Riccio, Luca Dei Giudici
Massive rotator cuff tears are difficult to treat surgically due to retraction, degeneration and fraying of the ends of torn tendons, severe fatty infiltration and atrophy of the respective muscles. Procedures developed to close the gap between the rotator cuff and the greater tuberosity of the humerus, such as soft tissue release may be inadequate for large tears. Human or porcine dermal allografts still have uncertain benefits, and tendon transfers seem to be associated with poor outcomes, donor site morbidity and altered mechanics...
July 2016: Joints
https://www.readbyqxmd.com/read/27896688/design-simulation-and-modelling-of-auxiliary-exoskeleton-to-improve-human-gait-cycle
#20
O Ashkani, A Maleki, N Jamshidi
Exoskeleton is a walking assistance device that improves human gait cycle through providing auxiliary force and transferring physical load to the stronger muscles. This device takes the natural state of organ and follows its natural movement. Exoskeleton functions as an auxiliary device to help those with disabilities in hip and knee such as devotees, elderly farmers and agricultural machinery operators who suffer from knee complications. In this research, an exoskeleton designed with two screw jacks at knee and hip joints...
November 28, 2016: Australasian Physical & Engineering Sciences in Medicine
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