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Nerve transfer

Frederic Marmel, Miriam I Marrufo-Pérez, Jan Heeren, Stephan Ewert, Enrique A Lopez-Poveda
The detection of high-frequency spectral notches has been shown to be worse at 70-80 dB sound pressure level (SPL) than at higher levels up to 100 dB SPL. The performance improvement at levels higher than 70-80 dB SPL has been related to an 'ideal observer' comparison of population auditory nerve spike trains to stimuli with and without high-frequency spectral notches. Insofar as vertical localization partly relies on information provided by pinna-based high-frequency spectral notches, we hypothesized that localization would be worse at 70-80 dB SPL than at higher levels...
June 14, 2018: Hearing Research
Peter J Ciolek, Brandon L Prendes, Michael A Fritz
INTRODUCTION: The reconstructive goals following radical parotidectomy include restoration of symmetry, reanimation of the face, and reestablishment of oral competence. We present our experience utilizing the anterolateral thigh (ALT) free flap, orthodromic temporalis tendon transfer (OTTT), and facial nerve cable grafting to reestablish form and function. MATERIAL AND METHODS: From 2010 to 2016, 17 patients underwent radical parotidectomy followed by immediate reconstruction...
June 7, 2018: American Journal of Otolaryngology
Tetsushi Aizawa, Masahiro Kuwabara, Satoshi Kubo, Shimpo Aoki, Ryuichi Azuma, Tomoharu Kiyosawa
BACKGROUND: Frey syndrome is one of the important complications of parotid surgery. Placing a barrier between the parotid gland and the skin flap is considered to be effective for preventing this syndrome by blocking misdirected regeneration of nerve fibers. Neoveil is nonwoven polyglycolic acid (PGA) felt that is used as absorbable reinforcing material. The present study evaluated the effectiveness of this PGA felt as a barrier for preventing Frey syndrome. METHODS: A total of 19 patients who underwent superficial parotidectomy from 2012 to 2017 were retrospectively reviewed...
June 13, 2018: Annals of Plastic Surgery
Husam A AlTahan, Roaa R Amer, Areej A Madani, Eman A Bakhsh
BACKGROUND Epidural venous plexus (EVP) engorgement occurs due to many conditions, so it can be easily misdiagnosed. This becomes problematic when the diagnosis requires prompt treatment for a good outcome, especially when it results in cauda equina syndrome (CES). We report a case of extensive iliocaval thrombosis leading to epidural venous plexus and ascending lumbar vein engorgement as an outcome of deep venous thrombosis (DVT) due to probable adverse effects of oral combined contraceptive pills (OCCP). CASE REPORT A 42-year-old woman presented to a rural medical facility with bilateral lower-limb swelling and skin darkening for 2 days...
June 15, 2018: American Journal of Case Reports
Kai-Xiang Yang, Shao-Hua Zhang, Da-Wei Ge, Tao Sui, Hong-Tao Chen, Xiao-Jian Cao
The study aimed to demonstrate the feasibility of an extradural nerve anastomosis technique for the restoration of a C5 and C6 avulsion of the brachial plexus. Nine fresh frozen human cadavers were used. The diameters, sizes, and locations of the extradural spinal nerve roots were observed. The lengths of the extradural spinal nerve roots and the distance between the neighboring nerve root outlets were measured and compared in the cervical segments. In the spinal canal, the ventral and dorsal roots were separated by the dura and arachnoid...
June 8, 2018: Journal of Biomedical Research
Steven F DeFroda, Joseph A Gil, Brett D Owens
There are several treatment options for recurrent shoulder instability. The Latarjet addresses bone loss via coracoid transfer, and creates a "sling effect" on the humeral head with the conjoint tendon. It does however carry a high potential risk of complications including graft resorption, hardware failure, and neurologic injury. It is hypothesized that the long head of the biceps can function similarly, without the donor site morbidity of a coracoid transfer. We present a case of recurrent instability and musculocutaneous nerve palsy following primary arthroscopic stabilization three years prior, and treatment via long head of the biceps stabilization...
June 2018: Journal of Orthopaedics
Edoardo Dalla Pozza, Bahar Bassiri Gharb, Francis A Papay, Richard L Drake, Andrew Steckler, Antonio Rampazzo
BACKGROUND: Hand transplantation in patients with severe upper extremity burns can be associated with an increased risk of exposure of vessels, tendons and nerves because of extensive skin and soft tissue deficit. This study evaluated how to reliably transfer additional extended skin flaps with a standard hand allograft. METHODS: Twenty-five upper extremities were used. Sixteen were injected with latex to map the perforating branches of the brachial (BA), superior ulnar collateral (SUCA), radial (RA), ulnar (UA) and posterior interosseous (PIA) arteries...
May 19, 2018: Plastic and Reconstructive Surgery
Joanna Stragierowicz, Krystyna Sitarek, Bartłomiej Grobelski, Anna Kilanowicz-Sapota
OBJECTIVES: Due to structural and toxicological similarities to 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD), polychlorinated naphthalenes (PCNs) were included in the Stockholm Convention on Persistent Organic Pollutants (POPs) in 2015. Hexachloronaphthalene (HxCN) is considered to be one of the most toxic congeners of PCNs. The objective of this study was to determine the maternal and fetal tissue concentrations of hexachloronaphthalene after a single administration...
June 4, 2018: International Journal of Occupational Medicine and Environmental Health
Stavros I Dimitriadis, Avraam D Marimpis
A brain-computer interface (BCI) is a channel of communication that transforms brain activity into specific commands for manipulating a personal computer or other home or electrical devices. In other words, a BCI is an alternative way of interacting with the environment by using brain activity instead of muscles and nerves. For that reason, BCI systems are of high clinical value for targeted populations suffering from neurological disorders. In this paper, we present a new processing approach in three publicly available BCI data sets: (a) a well-known multi-class ( N = 6) coded-modulated Visual Evoked potential (c-VEP)-based BCI system for able-bodied and disabled subjects; (b) a multi-class ( N = 32) c-VEP with slow and fast stimulus representation; and (c) a steady-state Visual Evoked potential (SSVEP) multi-class ( N = 5) flickering BCI system...
2018: Frontiers in Neuroinformatics
Chen Hua, Xi Yang, Yunbo Jin, Yun Zou, Hui Chen, Gang Ma, Yajin Qiu, Xiaojie Hu, Mathias Tremp, Xiaoxi Lin
BACKGROUND: Head and neck arteriovenous malformations (AVMs) involving branches of the facial nerve often cause tremendous cosmetic, functional, and psychological problems that are challenging to treat. We proposed an algorithm to obtain the optimal treatment and esthetic outcome. METHODS: Medical records of 24 patients were reviewed between 2002 and 2015. The lesions were classified into 4 types: type 1, involving no more than 2 facial nerve branches, with a maximal diameter of lesion of 5 cm or less (n = 7); type 2, involving no less than 2 facial nerve branches, with a maximal diameter of lesion of greater than 5 cm (type 2a, facial nerve preservation, n = 8; type 2b, facial reanimation, n = 5); and type 3, involving the mastoid segments or the trunk of the facial nerve (n = 4)...
May 30, 2018: Annals of Plastic Surgery
Imran Ratanshi, Tod A Clark, Jennifer L Giuffre
Intraneural ganglion cysts, which occur within the common peroneal nerve, are a rare cause of foot drop. The current standard of treatment for intraneural ganglion cysts involving the common peroneal nerve involves (1) cyst decompression and (2) ligation of the articular nerve branch to prevent recurrence. Nerve transfers are a time-dependent strategy for recovering ankle dorsiflexion in cases of high peroneal nerve palsy; however, this modality has not been performed for intraneural ganglion cysts involving the common peroneal nerve...
May 2018: Plastic Surgery
Kyeong Ryang Ko, Junghun Lee, Deokho Lee, Boram Nho, Sunyoung Kim
During the peripheral nerve regeneration process, a variety of neurotrophic factors play roles in nerve repair by acting on neuronal or non-neuronal cells. In this report, we investigated the role(s) of hepatocyte growth factor (HGF) and its receptor, c-met, in peripheral nerve regeneration. When mice were subjected to sciatic nerve injury, the HGF protein level was highly increased at the injured and distal sites. The level of both total and phosphorylated c-met was also highly upregulated, but almost exclusively in Schwann cells (SCs) distal from the injury site...
May 29, 2018: Scientific Reports
Depeng Meng, Jun Zhou, Yaofa Lin, Zheng Xie, Huihao Chen, Ronghua Yu, Haodong Lin, Chunlin Hou
BACKGROUND: Quadriceps palsy is mainly caused by proximal lesions in the femoral nerve. The obturator nerve has been previously used to repair the femoral nerve, although only a few reports have described the procedure, and the outcomes have varied. In the present study, we aimed to confirm the feasibility and effectiveness of this treatment in a rodent model using the randomized control method. METHODS: Sixty Sprague-Dawley rats were randomized into two groups: the experimental group, wherein rats underwent femoral neurectomy and obturator nerve transfer to the femoral nerve motor branch; and the control group, wherein rats underwent femoral neurectomy without nerve transfer...
May 28, 2018: Acta Neurochirurgica
Qichao Li, Zhangmin Liu, Junyue Lu, Wenchai Shao, Xiaobo Feng
Objective: To investigate the effectiveness of transferring the ulnaris proper digital nerve of index finger and its dorsal branch to repair the thumb nerve avulsion. Methods: Between January 2007 and May 2015, 23 patients with thumb nerve avulsion were treated by transferring the ulnaris proper digital nerve of index finger and its dorsal branch. There were 17 males and 6 females with an average age of 32 years (range, 16-63 years). The injuries were caused by machine twist in 10 cases, electric saw in 8 cases, and sharp article prick in 5 cases...
August 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
Dajiang Song, Zan Li, Xiao Zhou, Songlin Xie
Objective: To explore the feasibility of harvesting free thinned innervated anterolateral thigh (ALT) perforator flap for repairing the donor defect after wrap-around flap transfer. Methods: Between May 2011 and December 2013, free thinned innervated ALT perforator flap was used to repair the donor defects after wrap-around flap transfer in 9 patients. There were 8 males and 1 female, with a mean age of 31.2 years (range, 19-42 years). The interval time between injury and admission was 3-12 hours (mean, 6...
August 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
Raluca Eugenia Iorga, Ruxandra Mihailovici, Manuela Ramona Ozturk, Dănuţ Costin
Leber's hereditary optic neuropathy is the most common mitochondrial condition and is characterized by bilateral, painless, subacute visual loss that develops during young adult life. LHON is a rare condition and this lack of knowledge can make doctors suspect and treat for other causes of vision loss. Typically, a series of tests are performed to confirm LHON diagnosis or exclude any other conditions. We presented the case of two brothers, HB, of 40 years old and HF, of 38 years old, who presented with a decrease in visual acuity in both eyes...
January 2018: Romanian Journal of Ophthalmology
Thomas Tyszkiewicz, Isam Atroshi
Flexor pollicis longus paralysis related to idiopathic anterior interosseous nerve syndrome is well known, but few reports exist on bilateral disease. A 24-year-old man with no personal or family history of neurological disease developed isolated total loss of active flexion of the right thumb's interphalangeal joint after undergoing a wrist arthroscopy. Surgical exploration 5 weeks after onset showed flexor pollicis longus tendon to be intact; anterior interosseous nerve decompression was done with no abnormalities found...
2018: SAGE Open Medical Case Reports
Christopher M LaPrade, Andrew S Bernhardson, Zachary S Aman, Gilbert Moatshe, Jorge Chahla, Grant J Dornan, Robert F LaPrade, Matthew T Provencher
BACKGROUND: Although previous literature has described the relevant anatomy for an open anterior Bankart approach of the shoulder, there is little known regarding the anatomic relationship changes in the neurovascular structures after an open Latarjet procedure. PURPOSE: To define the neurovascular anatomy of the native shoulder in relation to the coracoid and to define the anatomy after the Latarjet procedure in relation to the glenoid to determine distances to these neurovascular structures with and without neurolysis of the musculocutaneous nerve (MCN) from the conjoint tendon...
May 1, 2018: American Journal of Sports Medicine
Chunyan Sun, Wei Xiong, Wei Dong Ye, Yingxuan Zheng, Ran Duan, Yanke Che, Jincai Zhao
In this work, we report the fast and ultrasensitive detection of a nerve agent simulant in the gas phase, diethyl chloro-phosphate (DCP), by using carbazole-based nanofibers from 1. When exposed to trace DCP, the formed pyridine-phosphorylated product in 1 nanofibers can cause amplified ratiometric fluorescence responses, i.e., amplified fluores-cence quenching via quenching excitons within the diffusion length of 1 nanofibers and simultaneously amplified turn-on fluorescence responses via harvesting excitons within the diffusion length to give the intramolecular charge transfer (ICT) emission at a longer wavelength...
May 24, 2018: Analytical Chemistry
Gerald Z Zhuang, Udita Upadhyay, Xiaoying Tong, Yuan Kang, Diana M Erasso, Eugene S Fu, Konstantinos D Sarantopoulos, Eden R Martin, Tim Wiltshire, Luda Diatchenko, Shad B Smith, William Maixner, Roy C Levitt
Carbonic anhydrase-8 (Car8; murine gene symbol) is an allosteric inhibitor of inositol trisphosphate receptor-1 (ITPR1), which regulates neuronal intracellular calcium release. We previously reported that wild-type Car8 overexpression corrects the baseline allodynia and hyperalgesia associated with calcium dysregulation in the waddle (wdl) mouse due to a 19 bp deletion in exon 8 of the Car8 gene. In this report, we provide preliminary evidence that overexpression of the human wild-type ortholog of Car8 (CA8 WT ), but not the reported CA8 S100P loss-of-function mutation (CA8 MT ), inhibits nerve growth factor (NGF)-induced phosphorylation of ITPR1, TrkA (NGF high-affinity receptor), and ITPR1-mediated cytoplasmic free calcium release in vitro...
April 24, 2018: Gene Therapy
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