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https://www.readbyqxmd.com/read/29774842/detection-of-low-pathogenicity-influenza-a-h7n3-virus-during-duck-mortality-event-cambodia-2017
#1
Annika Suttie, Sokhoun Yann, Phalla Y, Sothyra Tum, Yi-Mo Deng, Vibol Hul, Viseth Srey Horm, Ian Barr, Andrew Greenhill, Paul F Horwood, Kristina Osbjer, Erik A Karlsson, Philippe Dussart
In January 2017, an estimated 3,700 (93%) of 4,000 Khaki Campbell ducks (Anas platyrhynchos domesticus) died in Kampong Thom Province, Cambodia. We detected low pathogenicity avian influenza A(H7N3) virus and anatid herpesvirus 1 (duck plague) in the affected flock; however, the exact cause of the mortality event remains unclear.
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29774294/seroprevalence-and-awareness-of-porcine-cysticercosis-across-different-pig-production-systems-in-south-central-cambodia
#2
Aderosoye Adenuga, Ana Mateus, Chhay Ty, Khieu Borin, Davun Holl, Sorn San, Victoria Duggan, Madeleine Clark, Gavin J D Smith, Richard Coker, Andrew Vaughn, James W Rudge
Background: Taeniasis/cysticercosis, caused by the pork tapeworm Taenia solium , represents an important public health and economic burden in endemic countries. However, there is a paucity of data on infection among pigs in many parts of Southeast Asia, particularly Cambodia. We aimed to estimate seroprevalence of porcine cysticercosis, and investigate husbandary practices and knowledge of the disease among livestock workers, across different pig sector units in south-central Cambodia...
February 2018: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29770612/identification-of-novel-mutations-causing-pediatric-cataract-in-bhutan-cambodia-and-sri-lanka
#3
Shari Javadiyan, Sionne E M Lucas, Dechen Wangmo, Meng Ngy, Kapila Edussuriya, Jamie E Craig, Adam Rudkin, Robert Casson, Dinesh Selva, Shiwani Sharma, Karen M Lower, James Meucke, Kathryn P Burdon
BACKGROUND: Pediatric cataract is an important cause of blindness and visual impairment in children. A large proportion of pediatric cataracts are inherited, and many genes have been described for this heterogeneous Mendelian disease. Surveys of schools for the blind in Bhutan, Cambodia, and Sri Lanka have identified many children with this condition and we aimed to identify the genetic causes of inherited cataract in these populations. METHODS: We screened, in parallel, 51 causative genes for inherited cataracts in 33 probands by Ampliseq enrichment and sequencing on an Ion Torrent PGM...
May 16, 2018: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/29764451/phenotypic-and-genotypic-characterization-of-thai-isolates-of-plasmodium-falciparum-after-an-artemisinin-resistance-containment-project
#4
Thunyapit Thita, Pimrat Jadsri, Jarupatr Thamkhantho, Toon Ruang-Areerate, Nantana Suwandittakul, Naruemon Sitthichot, Kittiya Mahotorn, Peerapan Tan-Ariya, Mathirut Mungthin
BACKGROUND: In Thailand, artemisinin-based combination therapy (ACT) has been used to treat uncomplicated falciparum malaria since 1995. Unfortunately, artemisinin resistance has been reported from Thailand and other Southeast Asian countries since 2003. Malarone® , a combination of atovaquone-proguanil (ATQ-PG), has been used to cease artemisinin pressure in some areas along Thai-Cambodia border, as part of an artemisinin resistance containment project since 2009. This study aimed to determine genotypes and phenotypes of Plasmodium falciparum isolates collected from the Thai-Cambodia border after the artemisinin resistance containment project compared with those collected before...
May 15, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29764422/hmmibd-software-to-infer-pairwise-identity-by-descent-between-haploid-genotypes
#5
Stephen F Schaffner, Aimee R Taylor, Wesley Wong, Dyann F Wirth, Daniel E Neafsey
BACKGROUND: A number of recent malaria studies have used identity by descent (IBD) to study epidemiological processes relevant to malaria control. In this paper, a software package, hmmIBD, is introduced for estimating pairwise IBD between haploid genomes, such as those of the malaria parasite, sampled from one or two populations. Source code is freely available. METHODS: The performance of hmmIBD was verified using simulated data and benchmarked against an existing method for detecting IBD within populations...
May 15, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29763452/factors-affecting-forest-area-change-in-southeast-asia-during-1980-2010
#6
Nobuo Imai, Takuya Furukawa, Riyou Tsujino, Shumpei Kitamura, Takakazu Yumoto
While many tropical countries are experiencing rapid deforestation, some have experienced forest transition (FT) from net deforestation to net reforestation. Numerous studies have identified causative factors of FT, among which forest scarcity has been considered as a prerequisite for FT. In fact, in SE Asia, the Philippines, Thailand and Viet Nam, which experienced FT since 1990, exhibited a lower remaining forest area (30±8%) than the other five countries (68±6%, Cambodia, Indonesia, Laos, Malaysia, and Myanmar) where forest loss continues...
2018: PloS One
https://www.readbyqxmd.com/read/29758170/comparison-of-human-milk-fatty-acid-composition-of-women-from-cambodia-and-australia
#7
Chang Gao, Ge Liu, Kyly C Whitfield, Hou Kroeun, Timothy J Green, Robert A Gibson, Maria Makrides, Shao J Zhou
BACKGROUND: Human milk is a rich source of omega-3 long-chain polyunsaturated fatty acids, which are postulated to be important for brain development. There is a lack of data on the human milk fatty acid composition of Cambodian women compared with data from Western women. Research Aim: The aim of this study was to determine the human milk fatty acid composition of women living in Cambodia and compare it with that of women living in Australia. METHOD: Human milk samples from Cambodian ( n = 67) and Australian ( n = 200) mothers were collected at 3 to 4 months postpartum...
May 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29751449/industrial-pollution-load-assessment-in-phnom-penh-cambodia-using-an-industrial-pollution-projection-system
#8
Vibol San, Vin Spoann, Johannes Schmidt
Approximately 56% out of the total 1302 Cambodian firms are operated in the Capital city of Cambodia. The necessary information on industrial pollution to set strategies, priorities and action plans on environmental protection issues is absent in Cambodia. In the absence of this data, effective environmental protection cannot be implemented. The objective of this study is to estimate industrial pollution load by employing the Industrial Pollution Projection System, a rapid environmental management tool for assessment of pollution load, to produce a scientific rational basis for preparing future policy direction to reduce industrial pollution in Phnom Penh city...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29742870/unraveling-haplotype-diversity-of-the-apical-membrane-antigen-1-gene-in-plasmodium-falciparum-populations-in-thailand
#9
Lalita Lumkul, Vorthon Sawaswong, Phumin Simpalipan, Morakot Kaewthamasorn, Pongchai Harnyuttanakorn, Sittiporn Pattaradilokrat
Development of an effective vaccine is critically needed for the prevention of malaria. One of the key antigens for malaria vaccines is the apical membrane antigen 1 ( AMA -1) of the human malaria parasite Plasmodium falciparum , the surface protein for erythrocyte invasion of the parasite. The gene encoding AMA -1 has been sequenced from populations of P. falciparum worldwide, but the haplotype diversity of the gene in P. falciparum populations in the Greater Mekong Subregion (GMS), including Thailand, remains to be characterized...
April 2018: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/29739433/-because-if-we-talk-about-health-issues-first-it-is-easier-to-talk-about-human-trafficking-findings-from-a-mixed-methods-study-on-health-needs-and-service-provision-among-migrant-and-trafficked-fishermen-in-the-mekong
#10
Nicola S Pocock, Reena Tadee, Kanokwan Tharawan, Wansiri Rongrongmuang, Brett Dickson, Soksreymom Suos, Ligia Kiss, Cathy Zimmerman
BACKGROUND: Human trafficking in the fishing industry or "sea slavery" in the Greater Mekong Subregion is reported to involve some of the most extreme forms of exploitation and abuse. A largely unregulated sector, commercial fishing boats operate in international waters far from shore and outside of national jurisdiction, where workers are commonly subjected to life-threatening risks. Yet, research on the health needs of trafficked fishermen is sparse. This paper describes abuses, occupational hazards, physical and mental health and post-trafficking well-being among a systematic consecutive sample of 275 trafficked fishermen using post-trafficking services in Thailand and Cambodia...
May 9, 2018: Globalization and Health
https://www.readbyqxmd.com/read/29733242/four-decades-following-the-khmer-rouge-sociodemographic-factors-impacting-depression-anxiety-and-ptsd-in-cambodia
#11
Desiree M Seponski, Cindy J Lahar, Sareth Khann, Sovandara Kao, Tanja Schunert
BACKGROUND: Reliable population-based epidemiological data of Cambodian mental health is lacking. AIMS: This study identifies the prevalence of and factors associated with anxiety, depression and PTSD in Cambodian adults. METHODS: A nationally representative sample of Cambodian adults (N = 2690) was interviewed utilizing the Harvard Trauma Questionnaire (assessment of PTSD symptoms) and the Hopkins Symptom Checklist-25 (assessment of symptoms of anxiety and depression)...
May 7, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29724181/high-pregnancy-incidence-and-low-contraceptive-use-among-a-prospective-cohort-of-female-entertainment-and-sex-workers-in-phnom-penh-cambodia
#12
Putu Duff, Jennifer L Evans, Ellen S Stein, Kimberly Page, Lisa Maher
BACKGROUND: While HIV and unintended pregnancies are both occupational risks faced by female sex workers, the epidemiology of pregnancy and its drivers in this population remains understudied. This includes Cambodia, where the drivers of pregnancy among female entertainment and sex workers (FESW) remain unknown. The current study aimed to examine factors associated with incident pregnancy, as well as describe contraceptive use among FESW in Phnom Penh, Cambodia. METHODS: This analysis drew from the Young Women's Health Study (YWHS)-2, a 12-month observational cohort of 220 FESW aged 15-29 years, conducted between August 2009 and August 2010...
May 3, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29709036/insectivorous-bat-reproduction-and-human-cave-visitation-in-cambodia-a-perfect-conservation-storm
#13
Thona Lim, Julien Cappelle, Thavry Hoem, Neil Furey
Cave roosting bats represent an important component of Southeast Asian bat diversity and are vulnerable to human disturbance during critical reproductive periods (pregnancy, lactation and weaning). Because dramatic growth of cave tourism in recent decades has raised concerns about impacts on cave bats in the region, we assessed the reproductive phenology of two insectivorous species (Hipposideros larvatus sensu lato and Taphozous melanopogon) at three caves in Cambodia for 23 months in 2014-2016 and evaluated human visitation to these sites between 2007 and 2014...
2018: PloS One
https://www.readbyqxmd.com/read/29706310/the-associated-risk-factors-for-underweight-and-overweight-high-school-students-in-cambodia
#14
Yat Yen, Yumin Shi, Bunly Soeung, Ratny Seng, Channy Dy, Rathny Suy, Kimlong Ngin
PURPOSE: Overweight and underweight are one of the leading risk factors for non-communicable diseases (NCDs), but little research on this area has been undertaken in Cambodia. Therefore, this study aimed to measure underweight and overweight and their associated risk behaviors among Cambodian high school students. METHODS: 3806 students (mean ag = 15.65 years, SD = 1.80, age range = 11-18 years) from the 2013 Cambodia-Global School-based Student Health Survey were used to yield representative samples of the Cambodian students...
April 21, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29703425/effect-of-generalised-access-to-early-diagnosis-and-treatment-and-targeted-mass-drug-administration-on-plasmodium-falciparum-malaria-in-eastern-myanmar-an-observational-study-of-a-regional-elimination-programme
#15
Jordi Landier, Daniel M Parker, Aung Myint Thu, Khin Maung Lwin, Gilles Delmas, François H Nosten
BACKGROUND: Potentially untreatable Plasmodium falciparum malaria threatens the Greater Mekong subregion. A previous series of pilot projects in Myanmar, Laos, Cambodia, and Vietnam suggested that mass drug administration was safe, and when added to provision of early diagnosis and treatment, could reduce the reservoir of P falciparum and interrupts transmission. We examined the effects of a scaled-up programme of this strategy in four townships of eastern Myanmar on the incidence of P falciparum malaria...
April 24, 2018: Lancet
https://www.readbyqxmd.com/read/29698516/how-to-combat-emerging-artemisinin-resistance-lessons-from-the-three-little-pigs
#16
Thanat Chookajorn
It is rare to come across an Aesop's fable in respectable journals. It might catch scientists outside the malaria field by surprise to learn that the famous story of "The Boy Who Cried Wolf" has been repeatedly compared to the threat from artemisinin-resistant malaria parasites, including the two latest reports on the rise of a specific haplotype in Cambodia and Thailand, sensationally dubbed "Super Malaria" by the media [1, 2]. The comparison to a children's tale should not negate the fact that malaria drug resistance is one of the most pressing threats to the global public health community...
April 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29694372/data-quality-and-timeliness-of-outbreak-reporting-system-among-countries-in-greater-mekong-subregion-challenges-for-international-data-sharing
#17
Saranath Lawpoolsri, Jaranit Kaewkungwal, Amnat Khamsiriwatchara, Ly Sovann, Bun Sreng, Bounlay Phommasack, Viengsavanh Kitthiphong, Soe Lwin Nyein, Nyan Win Myint, Nguyen Dang Vung, Pham Hung, Mark S Smolinski, Adam W Crawley, Moe Ko Oo
Cross-border disease transmission is a key challenge for prevention and control of outbreaks. Variation in surveillance structure and national guidelines used in different countries can affect their data quality and the timeliness of outbreak reports. This study aimed to evaluate timeliness and data quality of national outbreak reporting for four countries in the Mekong Basin Disease Surveillance network (MBDS). Data on disease outbreaks occurring from 2010 to 2015 were obtained from the national disease surveillance reports of Cambodia, Lao PDR, Myanmar, and Vietnam...
April 25, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29691702/nutritional-composition-of-the-diet-of-the-northern-yellow-cheeked-crested-gibbon-nomascus-annamensis-in-northeastern-cambodia
#18
Naven Hon, Alison M Behie, Jessica M Rothman, Ken G Ryan
This study measured the nutritional composition of foods consumed by the northern yellow-cheeked crested gibbon (Nomascus annamensis) in northeastern Cambodia. One group of N. annamensis was studied, and focal animal sampling was used to observe their feeding behavior. The study was conducted for 4 months (January-April 2015) in the dry season and 69 foods were collected for nutritional analyses. N. annamensis fed on 37 plant species, but only seven species made up more than 80% of feeding time. N. annamensis spent the majority of their time feeding on fruit (60...
April 24, 2018: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/29690902/use-of-family-planning-and-child-health-services-in-the-private-sector-an-equity-analysis-of-12-dhs-surveys
#19
Nirali M Chakraborty, Andrea Sprockett
BACKGROUND: A key component of universal health coverage is the ability to access quality healthcare without financial hardship. Poorer individuals are less likely to receive care than wealthier individuals, leading to important differences in health outcomes, and a needed focus on equity. To improve access to healthcare while minimizing financial hardships or inequitable service delivery we need to understand where individuals of different wealth seek care. To ensure progress toward SDG 3, we need to specifically understand where individuals seek reproductive, maternal, and child health services...
April 24, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29690890/a-novel-field-based-molecular-assay-to-detect-validated-artemisinin-resistant-k13-mutants
#20
Laurence Vachot-Ganée, Nimol Khim, Alexandra Iannello, Eric Legrand, Saorin Kim, Rotha Eam, Chanra Khean, Malen Ken, Elizabeth Ashley, Kyaw Myo Tun, Mehul Dhorda, François Nosten, Issa Mahamat Souleymane, Sophie Blein, Alexandre Pachot, Frédéric Ariey, Karine Kaiser, Didier Ménard
BACKGROUND: Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be expedited. Molecular biology techniques used for monitoring rely on the detection of k13 validated mutants by using PCR and Sanger sequencing approach, usually not available in malaria endemic areas. METHODS: A semi-automated workflow based on the easyMAG® platform and the Argene Solution® (bioMérieux, Marcy l'Etoile, France) as a field-based surveillance tool operable at national level was developed in four steps...
April 24, 2018: Malaria Journal
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