Luca Caschera, Giorgio Fiore, Simone Nava, Stefania Criscuolo, Francesco M Lo Russo, Silvia Casale, Giorgio Conte, Giulia Platania, Antonella Costa, Giorgio Carrabba, Marco Locatelli, Fabio Maria Triulzi
Diabetic ketoacidosis (DKA) is a serious complication in children with diabetes mellitus type 1 (DM1). In rare and severe cases DKA may be complicated by cerebral edema, central brain herniation and cerebral infarctions. We present the magnetic resonance imaging findings in a child with DKA and central nervous system involvement; diffusion tensor imaging (DTI) and functional MRI (fMRI) were performed to assess the white matter integrity of sensory pathways and cortical sensory processing. Conventional imaging showed bilateral uncal herniation, effacement of the perimesencephalic cisterns, wide ischemic lesions in the posterior cerebral artery (PCA) territories, sagging brainstem and Duret's hemorrhage consistent with signs of central brain herniation and intracranial hypertension...
April 23, 2024: Neuroradiology Journal