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https://www.readbyqxmd.com/read/28817602/exploring-the-potential-of-a-structural-alphabet-based-tool-for-mining-multiple-target-conformations-and-target-flexibility-insight
#1
Leslie Regad, Jean-Baptiste Chéron, Dhoha Triki, Caroline Senac, Delphine Flatters, Anne-Claude Camproux
Protein flexibility is often implied in binding with different partners and is essential for protein function. The growing number of macromolecular structures in the Protein Data Bank entries and their redundancy has become a major source of structural knowledge of the protein universe. The analysis of structural variability through available redundant structures of a target, called multiple target conformations (MTC), obtained using experimental or modeling methods and under different biological conditions or different sources is one way to explore protein flexibility...
2017: PloS One
https://www.readbyqxmd.com/read/28807431/a-prospective-analysis-of-injury-rates-patterns-and-causes-in-cliff-and-splash-diving
#2
Lukas Ernstbrunner, Armin Runer, Paul Siegert, Matthäus Ernstbrunner, Johannes Becker, Thomas Freude, Herbert Resch, Philipp Moroder
INTRODUCTION: Information about injuries and its differences in Cliff Diving (CD) and Splash Diving (SD) are unknown. It was the aim to analyse (1) injury rates, patterns and causes; (2) differences (in injuries) between both disciplines; and to (3) identify targets for future injury prevention interventions. METHODS: From April to November 2013, 81 cliff and 51 splash divers were prospectively surveyed with an encrypted, monthly e-mail-based questionnaire. RESULTS: During a total of 7857h diving with an average diving height of 13 (±7)m, an overall injury rate of 7...
August 5, 2017: Injury
https://www.readbyqxmd.com/read/28797173/sphenoid-sinus-barotrauma-in-diving-case-series-and-review-of-the-literature
#3
Jochen D Schipke, Sinclair Cleveland, Markus Drees
About 50% of scuba divers have suffered from barotrauma of the ears and about one-third from barotrauma of paranasal sinuses. The sphenoid sinuses are rarely involved. Vital structures, as internal carotid artery and optic nerve, adjoin the sphenoid sinus. Thus, barotrauma could lead to serious neurologic disorders, including blindness. After searching the literature (Medline) and other sources (Internet), we present some cases of sphenoid sinus barotrauma, because these injuries may be underreported and misdiagnosed due to the lack of awareness and knowledge...
August 10, 2017: Research in Sports Medicine
https://www.readbyqxmd.com/read/28796448/matters-of-scale-sociology-in-and-for-a-complex-world
#4
Olli Pyyhtinen
The article proposes that if sociology is to make sense of a world that is ever more complex and complicated, it is important to reconsider the scale(s) of our relations and actions. Instead of assuming a nested vertical hierarchy of the micro to macro binary, scale should be treated not only as multiple, but also as something produced and sustained in practice. Coming to grips with the complex world, we are living in also necessitates attending to the conduits and connections between various sites, fields, and terrains to which our lives are entangled...
August 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/28789677/cold-adaptation-aging-and-korean-women-divers-haenyeo
#5
REVIEW
Joo-Young Lee, Joonhee Park, Siyeon Kim
BACKGROUND: We have been studying the thermoregulatory responses of Korean breath-hold women divers, called haenyeo, in terms of aging and cold adaptation. During the 1960s to the 1980s, haenyeos received attention from environmental physiologists due to their unique ability to endure cold water while wearing only a thin cotton bathing suit. However, their overall cold-adaptive traits have disappeared since they began to wear wetsuits and research has waned since the 1980s. For social and economic reasons, the number of haenyeos rapidly decreased to 4005 in 2015 from 14,143 in 1970 and the average age of haenyeos is about 75 years old at present...
August 8, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/28783886/cerebrospinal-vascular-diseases-misdiagnosed-as-decompression-illness-the-importance-of-considering-other-neurological-diagnoses
#6
Kiyotaka Kohshi, Yoshitaka Morimatsu, Hideki Tamaki, Yukio Murata, Katsuko Kohshi, Tatsuya Ishitake, Petar J Denoble
The diagnosis of decompression illness (DCI), which is based on a history of decompression and clinical findings, can sometimes be confounded with other vascular events of the central nervous system. The authors report three cases of divers who were urgently transported to a hyperbaric facility for hyperbaric oxygen treatment of DCI which at admission turned out to be something else. The first case, a 45-year-old experienced diver with unconsciousness, was clinically diagnosed as having experienced subarachnoid hemorrhage, which was confirmed by CT scan...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28783885/performance-of-life-support-breathing-apparatus-for-under-ice-diving-operations
#7
Michael A Lang, John R Clarke
INTRODUCTION: Single-hose scuba regulators dived in very cold water may suffer first- or second-stage malfunction, yielding complete occlusion of air flow or massive freeflow that rapidly expends a diver's air supply. PURPOSE: This study, conducted in Antarctica, evaluated the under-ice performance of a sampling of commercially available regulators. METHODS: Seventeen science divers logged a total of 305 dives in -1.86°C seawater under 6-meter-thick Antarctic fast-ice over two field seasons in 2008 and 2009...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777907/elimination-of-ct-detected-gas-bubbles-derived-from-decompression-illness-with-abdominal-symptoms-after-a-short-hyperbaric-oxygen-treatment-in-a-monoplace-chamber-a-case-report
#8
Takuya Oyaizu, Mitsuhiro Enomoto, Toshihide Tsujimoto, Yasushi Kojima, Atsushi Okawa, Kazuyoshi Yagishita
We report the case of a 54-year-old male compressed-air worker with gas bubbles detected by computed tomography (CT). He had complained of strong abdominal pain 30 minutes after decompression after working at a pressure equivalent to 17 meters of sea water for three hours. The initial CT images revealed gas bubbles in the intrahepatic portal vein, pulmonary artery and bilateral femoral vein. After the first hyperbaric oxygen treatment (HBO₂ at 2.5 atmospheres absolute/ATA for 150 minutes), no bubbles were detected on repeat CT examination...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777905/decompression-sickness-among-diving-fishermen-in-mexico-observational-retrospective-analysis-of-dcs-in-three-sea-cucumber-fishing-seasons
#9
Oswaldo Huchim-Lara, Walter Chin, Silvia Salas, Normando Rivera-Canul, Salvador Cordero-Romero, Juan Tec, Ellie Joo, Nina Mendez-Dominguez
The probabilities of decompression sickness (DCS) among diving fishermen are higher than in any other group of divers. Diving behavior of artisanal fishermen has been directed mainly to target high-value species. The aim of this study was to learn about the occurrence of DCS derived from sea cucumber harvesting in the Yucatán Peninsula, Mexico. We conducted a retrospective chart review of diving fishermen treated at a multiplace hyperbaric chamber in Tizimín, Mexico. In total, 233 recompression therapies were rendered to 166 diving fishermen from 2014 to 2016...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777904/cardiovascular-and-respiratory-effects-of-the-neoprene-wetsuit-in-non-immersed-divers
#10
Claudio Marabotti, Renato Prediletto, Alessandro Scalzini, Alessandro Pingitore, Mirko Passera, Marco Laurino, Antonio L'Abatte
A neoprene wetsuit is widely used to reduce thermal dispersion during diving. Recent observations have pointed out that elastic recoil of the wetsuit might have significant compressive effects, able to affect water and electrolyte homeostasis during both dry and immersed conditions. The aim of this study was to evaluate the possible cardiovascular and respiratory effects of the neoprene wetsuit in dry conditions in a sample of experienced divers. Twenty-four (24) healthy divers were evaluated by Doppler-echocardiography and by spirometry in basal conditions and while wearing a full neoprene wetsuit...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777903/hypertension-screening-of-commercial-divers-from-an-occupational-medicine-perspective
#11
Alejandro Garbino, Robert W Sanders, Charles H Mathers
Hypertension is one of the most common chronic diseases in the world: in the United States, it affects one-third of the adult population. Most cases are primary hypertension - with no identified cause - and significantly increase risk for cardiovascular disease and stroke. At NASA's Neutral Buoyancy Laboratory (NBL), there is a cadre of professional divers who provide underwater support during extravehicular activity training (EVAs, commonly referred to as "spacewalks") for astronauts. The NBL occupational health program requires regular "work-site" physical exams, including blood pressure checks, on at least a weekly basis...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777522/recurrent-cutaneous-decompression-illness-after-pfo-device-implantation-a-case-report
#12
Martin Vanden EEde
It is well known that patency of the foramen ovale (PFO) is a risk factor for decompression illness (DCI) in scuba divers, even if they adhere to the currently accepted and used decompression tables (termed "an undeserved hit"). The correction of the PFO through percutaneous closure after DCI is an ongoing discussion. We describe a case of a diver who redeveloped a cutaneous DCI due to a recurrent PFO after initial treatment with an occluder device four years earlier.
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777521/blue-fingered-diver-case-report
#13
Rebecca Cable, Lindell K Weaver, Anne B Roberts, Greg Goodman, Kayla Deru
Although Raynaud's phenomenon is a well-known consequence of exposure to cold, neither its incidence in recreational divers nor case reports in that population have been reported in the medical literature. We present a case report of the initial manifestation of primary Raynaud's phenomenon during a warm-water scuba dive. A healthy 18-year-old Caucasian male made four open-circuit compressed air scuba dives over two days in the Florida Keys to a maximum depth of 90 feet. After two of those dives, he noted painless, blue discoloration on three digits of his left hand, unaccompanied by sensory changes, which resolved within an hour of surfacing...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777520/factors-influencing-adherence-to-pre-dive-checklists-among-recreational-scuba-divers
#14
Shabbar I Ranapurwala, Charles Poole, Stephen W Marshall, Kristen L Kucera, Petar J Denoble, Steve Wing
Pre-dive checklists can prevent mishaps, injuries, and deaths in recreational scuba diving. However, the prevalence of checklist use remains low. Understanding the environmental and individual factors influencing a diver's checklist use may help in promoting checklists. In the summer of 2012, 617 divers were enrolled in the intervention group of a cluster randomized trial. The divers received an intervention pre-dive checklist to use before they made dives. Logistic regression analyses were used to model adherence to pre-dive checklist with generalized estimating equations...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28774112/enhancing-the-hydrophilicity-and-cell-attachment-of-3d-printed-pcl-graphene-scaffolds-for-bone-tissue-engineering
#15
Weiguang Wang, Guilherme Caetano, William Stephen Ambler, Jonny James Blaker, Marco Andrey Frade, Parthasarathi Mandal, Carl Diver, Paulo Bártolo
Scaffolds are physical substrates for cell attachment, proliferation, and differentiation, ultimately leading to the regeneration of tissues. They must be designed according to specific biomechanical requirements, i.e., certain standards in terms of mechanical properties, surface characteristics, porosity, degradability, and biocompatibility. The optimal design of a scaffold for a specific tissue strongly depends on both materials and manufacturing processes, as well as surface treatment. Polymeric scaffolds reinforced with electro-active particles could play a key role in tissue engineering by modulating cell proliferation and differentiation...
December 7, 2016: Materials
https://www.readbyqxmd.com/read/28769060/a-diver-operated-hyperspectral-imaging-and-topographic-surveying-system-for-automated-mapping-of-benthic-habitats
#16
Arjun Chennu, Paul Färber, Glenn De'ath, Dirk de Beer, Katharina E Fabricius
We developed a novel integrated technology for diver-operated surveying of shallow marine ecosystems. The HyperDiver system captures rich multifaceted data in each transect: hyperspectral and color imagery, topographic profiles, incident irradiance and water chemistry at a rate of 15-30 m(2) per minute. From surveys in a coral reef following standard diver protocols, we show how the rich optical detail can be leveraged to generate photopigment abundance and benthic composition maps. We applied machine learning techniques, with a minor annotation effort (<2% of pixels), to automatically generate cm-scale benthic habitat maps of high taxonomic resolution and accuracy (93-97%)...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28768086/relationship-between-clinical-and-radiologic-findings-of-spinal-cord-injury-in-decompression-sickness
#17
Jae Myun Chung, Jin Young Ahn
BACKGROUND: Decompression sickness may involve the central nervous system. The most common site is spinal cord. This study was conducted to determine the relationship between magnetic resonance(MR) imaging findings of spinal damage. METHODS: We conducted a retrospective review of 12 patients (male=10, female=2) who presented with spinal cord symptoms. We investigated their clinical features, neurological findings and radiologic findings. RESULTS: The depth and bottom time of the dive were 34...
January 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28768085/scuba-in-older-aged-divers
#18
Michael B Strauss, Jeremy A Busch, Stuart S Miller
As the population gets older, coupled with increased awareness of good health practices and the recognition that fitness contributes to participation in activities generally appropriate for younger individuals, decisions need to be made about what are appropriate activities for the older-aged scuba (self-contained underwater breathing apparatus) diver. It is essential to appreciate the distinction between chronological and physiological age. Three factors, namely fitness, comorbidities, and mobility and strength are fundamental when making decisions about participation in activities in general as well as in scuba diving for older adults...
January 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28762565/influence-of-lung-volume-on-the-interaction-between-cardiac-output-and-cerebrovascular-regulation-during-extreme-apnoea
#19
Mike Stembridge, Ryan L Hoiland, Anthony R Bain, Otto F Barak, Ivan Drvis, David B MacLeod, Douglas M MacLeod, Dennis Madden, Tonci Batinic, Peter O'Donoghue, Rob Shave, Zeljko Dujic, Philip N Ainslie
We investigated the role of lung volume-induced changes in cardiac output (Q̇) on cerebrovascular regulation during prolonged apnoea. Fifteen elite apnoea divers (1F; 185 ± 7 cm, 82 ± 12 kg, 29 ± 7 years) attended the laboratory on two separate occasions and completed maximal breath-holds at total lung capacity (TLC) and functional residual capacity (FRC) to elicit disparate cardiovascular responses. Mean arterial pressure (MAP), internal jugular venous pressure (IJVP) and arterial blood gases were measured via cannulation, global cerebral blood flow (gCBF) was quantified by ultrasound and cardiac output via photoplethysmography...
August 1, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28751139/identification-of-driver-genes-and-key-pathways-of-pediatric-brain-tumor-and-comparison-of-molecular-pathogenesis-based-on-pathological-types
#20
Sheng Zhong, Bo Wu, Yujuan Han, Yingshu Cao, Liu Yang, Sean X Luo, Yong Chen, Huimao Zhang, Gang Zhao
OBJECTIVE: This study is to identify pediatric brain tumors (PBT) diver genes, key pathways, to detect the expression of the diver genes and also to clarify the relationship between patients' prognosis and diver genes expression. METHODS: The gene expression profile of GSE50161 was analyzed to identify the DEGs (Differentially Expressed Genes) between tumor tissue and the normal tissue. GO (Gene Ontology), KEGG (Kyoto Encyclopedia of Genes and Genomes) analysis and PPI (Protein-protein interation) network analysis were conducted to find out the enrichment functions, pathways and hub genes...
July 24, 2017: World Neurosurgery
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