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H Gasparyan, Derek Mariner, Christopher Wright, James Nicol, James Murphy, Chuan Liu, Christopher Proctor
ISO 4387 Standard determines the main aerosol constituents (total particulate matter, water, nicotine, and nicotine-free-dry-particulate matter, referred to as "tar") in cigarette mainstream smoke (ISO, 2000). Heated Tobacco Products (also called Tobacco Heating Products or Heat-not-Burn Products) are designed to form aerosol by heating tobacco rather than burning like in combustible cigarettes. In this study we have evaluated the suitability of ISO 4387 Standard to be adapted for quantifying main aerosol constituents for HTP aerosol...
September 19, 2018: Regulatory Toxicology and Pharmacology: RTP
Patricia Gallego-Muñoz, Elvira Lorenzo-Martín, Itziar Fernández, Cristina Herrero-Pérez, M Carmen Martínez-García
Nidogen-2 is a basement membrane (BM) glycoprotein that could be a key to understanding why defects in BM regeneration occur after severe trauma to the cornea. We monitored the location and expression of nidogen-2 during corneal repair after alkali burn in rabbits. In rabbits that received both general and ocular topical anaesthesia, the central cornea of the left eye was burned by placing an 8-mm diameter filter paper soaked in 0.5 N NaOH for 60 s. Right corneas were used as controls. The eyes were evaluated at 2, 7, 15, and 30 days after burning and analysed by immunohistochemistry for nidogen-2 and α-smooth muscle actin, a myofibroblast marker...
September 19, 2018: Experimental Eye Research
Egle Köster, Kajar Köster, Frank Berninger, Anatoly Prokushkin, Heidi Aaltonen, Xuan Zhou, Jukka Pumpanen
Rising air temperatures and changes in precipitation patterns in boreal ecosystems are changing the fire occurrence regimes (intervals, severity, intensity, etc.). The main impacts of fires are reported to be changes in soil physical and chemical characteristics, vegetation stress, degradation of permafrost, and increased depth of the active layer. Changes in these characteristics influence the dynamics of carbon dioxide (CO2 ) and methane (CH4 ) fluxes. We have studied the changes in CO2 and CH4 fluxes from the soil in boreal forest areas in central Siberia underlain by continuous permafrost and the possible impacts of the aforementioned environmental factors on the emissions of these greenhouse gases...
September 19, 2018: Journal of Environmental Management
Ying Pan, Longxiang Liu, Xin Wang, Lei Song, Yuan Hu
In this work, a facile method to manufacture the layer-by-layer (LbL) assembled coating with durable flame-resistant effect on the polyester-cotton blend fabrics was reported. The LbL coating modified polyester-cotton fabric was treated with positively charged polyethyleneimine (PEI) and negatively charged oxidized sodium alginate (OSA) successively. Subsequently, the PEI/OSA coating was cross-linked by hypophosphorous acid (HA). As characterized by X-ray photoelectron spectroscopy and scanning electron microscopy, the HA cross-linked PEI/OSA coatings were successfully deposited on the surfaces of polyester and cotton fibers...
December 1, 2018: Carbohydrate Polymers
Tam N Pham, Joshua N Wong, Tonya Terken, Nicole S Gibran, Gretchen J Carrougher, Aaron Bunnell
INTRODUCTION: The advent of consoles that deliver both interactive games and therapy may augment rehabilitation options in burn patients. The Jintronix software combines therapy-specific software and interactive gaming as a form of coaching and records patient performance on the Kinect® platform. Our objective was to determine the feasibility of a set of Jintronix games and therapy modules in hospitalized adult burn patients. METHODS: We conducted a prospective single center feasibility study from August through October 2016...
September 18, 2018: Burns: Journal of the International Society for Burn Injuries
Daniel S Kreitzberg, Dhiraj Murthy, Alexandra Loukas, Keryn E Pasch
No abstract text is available yet for this article.
September 6, 2018: Addictive Behaviors
Jackie Mc Ferguson, David Pépin, Chinwe Duru, Paul Matejtschuk, Patricia K Donahoe, Chris J Burns
RESEARCH QUESTION: Is formulated and lyophilized, recombinant human Müllerian inhibiting substance, also known as anti-Müllerian hormone (AMH), suitable for the preparation of a WHO international standard to calibrate AMH immunoassays? DESIGN: The AMH content of a trial preparation, coded SS-581, was determined by five laboratories using seven immunoassay methods. Participants were requested to report the content of the preparation in terms of their method calibrators through the measurement of a minimum of five concentrations in the linear part of the dose-response curve...
September 5, 2018: Reproductive Biomedicine Online
I Jardin, G Canlorbe, J-L Mergui, M Nikpayam, J Belghiti, C Uzan, H Azaïs
Genitourinary syndrome of menopause (GSM) brings together a collection of signs including vaginal dryness, burning sensation and itching discomfort as well as deterioration of sexual health, dysuria, urgenturia and repeated urinary infections and may be responsible for a significant impairment of quality of life in symptomatic postmenopausal women. The management of GSM therefore represents a public health issue. Systemic or local hormonal treatments are frequently offered, as well as non-hormonal treatments...
September 18, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
Gianmaria Pio, Ernesto Salzano
Natural gas represents an attractive fuel for industrialized and developing countries seeking an alternative to petroleum. Due to economic and safety considerations, liquefied natural gas (LNG) at cryogenic conditions is preferred for storage and transportation. The main drawback is the poor understanding of the physical and chemical phenomena that occur at the storage conditions of liquid methane, i.e. at ultra-low temperatures around 110 K and, if released, at temperatures below ambient. In this work, a procedure to evaluate the laminar burning velocity, the flammability limit (FL) and the limiting oxygen concentration (LOC) of methane-air-diluent mixtures based on detailed kinetic mechanism at ultra-low temperatures is proposed...
September 7, 2018: Journal of Hazardous Materials
Jason F Wang, Nicole M Hindman
No abstract text is available yet for this article.
September 18, 2018: Journal of the American Academy of Dermatology
Thittamaranahalli Muguregowda Honnegowda, Pramod Kumar, Padmanabha Udupa, Pragna Rao
Burn injuries constitute a major public health problem and account for a significant cause of mortality and morbidity amongst the Indian population. This 2-year prospective study was undertaken to find out the exact epidemiological determinants of 737 patients admitted with burn injuries and, thus, to try and formulate effective preventive strategies. This study was conducted in the department of plastic surgery and burns from September 2011 to June 2013. All consecutive patients with major burns admitted for in-hospital treatment during the study period were included in the study...
September 21, 2018: International Wound Journal
Ruth J Pepper, Stephen P McAdoo, Sarah M Moran, Dearbhla Kelly, Jennifer Scott, Sally Hamour, Aine Burns, Megan Griffith, Jack Galliford, Jeremy B Levy, Thomas D Cairns, Seerapani Gopaluni, Rachel B Jones, David Jayne, Mark A Little, Charles D Pusey, Alan D Salama
Objectives: Glucocorticoids (GCs) are a mainstay of treatment for patients with ANCA-associated vasculitis (AAV) but are associated with significant adverse effects. Effective remission induction in severe AAV using extremely limited GC exposure has not been attempted. We tested an early rapid GC withdrawal induction regimen for patients with severe AAV. Methods: Patients with active MPO- or PR3-ANCA vasculitis or ANCA-negative pauci-immune glomerulonephritis were included...
September 18, 2018: Rheumatology
Andrea Dai, Megan Moore, Anna Polyakovsky, Tracy Gooding, Tara Lerew, Gretchen J Carrougher, Nicole S Gibran, Tam N Pham
Introduction: Little is understood about the inpatient experience from the burn patients' perspectives. Rather, hospitals emphasize quantitative feedback as part of the ongoing process improvement. Comments returned with the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) administrative survey may provide important patient perspectives. We analyzed quantitative and qualitative HCAHPS data to identify areas for care improvement. Methods: We reviewed our burn center HCAHPS results over 2 years...
September 18, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
Andrew Murton, Fredrick J Bohanon, John O Ogunbileje, Karel D Capek, Ellen A Tran, Tony Chao, Labros S Sidossis, Craig Porter, David N Herndon
Sepsis is a common and often fatal consequence of severe burn injury, but its exact effects on whole body and muscle metabolism in the burn patient is unclear. To address this, 13 septic and 11 nonseptic patients (age: 36.9 ± 13.0 years) with burns encompassing >30% of their total body surface area underwent muscle protein kinetic studies under postabsorptive conditions using bolus injections of ring-C6 and N phenylalanine isotopes. In parallel, whole-body lipid and carbohydrate kinetics were assessed using constant infusions of [U-C6]palmitate, [6,6-H2]glucose, and [H5]glycerol, and during a 2-h hyperinsulinemic euglycemic clamp...
September 19, 2018: Shock
Justyna Glik, Armand Cholewka, Beata Englisz, Agata Stanek, Karolina Sieroń, Karolina Mikuś-Zagórska, Grzegorz Knefel, Mariusz Nowak, Marek Kawecki
BACKGROUND: One of the methods to treat chronic wounds is the use of hyperbaric oxygen (HBO). Objective measurement of the wound surface is an important element in the process of monitoring and predicting the progress of treatment. OBJECTIVES: The aim of the study was to evaluate the effect of hyperbaric oxygen therapy (HBOT) on ulcer wound healing in patients with chronic venous insufficiency ulcers and diabetic foot syndrome using thermal imaging and computerized planimetry...
September 21, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Kozeta Miliku, Janine F Felix, Trudy Voortman, Henning Tiemeier, Darryl W Eyles, Thomas H Burne, John J McGrath, Vincent W V Jaddoe
Maternal vitamin D deficiency during pregnancy may have persistent adverse effects on childhood growth and development. We examined whether 25-hydroxyvitamin D (25(OH)D) concentrations during pregnancy and at cord blood were associated with childhood body composition and cardiovascular outcomes. This study was embedded in a population-based prospective cohort in Rotterdam, The Netherlands, among 4,903 mothers and their offspring. We measured 25(OH)D concentrations at a median gestational age of 20.4 weeks (95% range 18...
September 21, 2018: Maternal & Child Nutrition
Teresa N P T Bui, Kristian F Mose, Flemming Andersen
No abstract text is available yet for this article.
September 20, 2018: Contact Dermatitis
Si Jack Chong, Yee Onn Kok, Rosanna Xiang Ying Tay, Desai Suneel Ramesh, Kok Chai Tan, Bien Keem Tan
Background: Inhalational injury is a major cause of morbidity and mortality in burns patients. This study aims to analyse the clinical outcomes, complications and bacteriology of inhalational burn patients. Methods: A prospective study was done on consecutive admissions to Burn Department, Singapore General Hospital over 15 months from January 2015 to March 2016. Presence of inhalational injury, demographics, complications and outcomes was recorded. Diagnosis of inhalational injury was based on history, symptoms and nasoendoscopy...
2018: Burns and Trauma
Nina Jovanovic, Admira Dizdarevic, Nedzad Dizdarevic, Amir Haracic, Lamija Gafurovic
Introduction: Eye lid reconstruction followed by severe, extensive body and facial burns represents a surgical challenge due to difficulties to obtain proper, healthy skin graft, tissue ischemia and necrosis. Presentation of case: We present a reconstructive lid surgery of cicatricial bilateral lower eyelid ectropion in a case of 31-year-old man who sustained thermal injuries, affecting more than 60% of total body surface area, causing severe, deep dermal burns...
October 2018: Annals of Medicine and Surgery
Lauren M Kropp, Christopher B Parsley, Omer Lee Burnett
Fire corals (Millepora spp) are the second most common reef-forming organisms and are frequently found in tropical and subtropical waters. Fire corals are not true corals but rather hydrozoans more closely related to jellyfish and sea nettles. Rigidly affixed to the reef and with a branching structure, each fire coral is a colony of numerous individual hydrozoans forming a collective symbiotic organism. It is common for divers to accidentally make contact with fire corals. Fire coral contact is characterized by the immediate onset of burning pain caused by venom discharge from numerous tiny nematocysts located externally on the creature...
September 17, 2018: Wilderness & Environmental Medicine
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