keyword
MENU ▼
Read by QxMD icon Read
search

Burn

keyword
https://www.readbyqxmd.com/read/28437853/inhibition-of-tgf-%C3%AE-signaling-promotes-expansion-of-human-epidermal-keratinocytes-in-feeder-cell-co-culture
#1
Daisuke Suzuki, Filipa Pinto, Makoto Senoo
Cultured epidermal autografts have been used worldwide since 1981 for patients with extensive third-degree burn wounds and limited skin donor sites. Despite significant progress in techniques toward improving clinical outcome of skin grafts, the long in vitro preparation time of cultured autografts has remained a major factor limiting its widespread use. Here, we show that pharmacological inhibition of TGF-β signaling promotes the expansion of human epidermal keratinocytes (HEKs) with high proliferative potential in co-cultures with both murine 3T3-J2 cells and human feeder cells, including dermal fibroblasts and preadipocytes...
April 24, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28437835/pten-downregulation-promotes-%C3%AE-oxidation-to-fuel-hypertrophic-liver-growth-after-hepatectomy-in-mice
#2
Ekaterina Kachaylo, Christoph Tschuor, Nicolas Calo, Nathalie Borgeaud, Perparim Limani, Anne-Christine Piguet, Jean-Francois Dufour, Michelangelo Foti, Rolf Graf, Pierre A Clavien, Bostjan Humar
In regenerating liver, hepatocytes accumulate lipids before the major wave of parenchymal growth. This transient, regeneration-associated steatosis (TRAS) is required for liver recovery, but its purpose is unclear. The tumor suppressor PTEN is a key inhibitor of the AKT-mTOR axis that regulates growth and metabolic adaptations after hepatectomy. In quiescent liver, PTEN causes pathological steatosis when lost, while its role in regenerating liver remains unknown. Here, we show that PTEN downregulation promotes liver growth in a TRAS-dependent way...
April 24, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28437511/online-information-on-the-treatment-of-burning-mouth-syndrome-quality-and-readability
#3
Shatha Alnafea, Stefano Fedele, Stephen Porter, Richeal Ni Riordain
AIMS: To evaluate the quality and readability of online information about the treatment of burning mouth syndrome (BMS). METHODS: An internet search using the phrase "burning mouth syndrome treatment" was carried out on the Google search engine (www.google.co.uk) on 8 June 2015, and the first 100 websites listed were examined. Data collection included DISCERN score, the Journal of the American Medical Association (JAMA) benchmarks for website analysis score, the presence of the Health on the Net (HON) Foundation seal, and the Flesch Reading Ease Score (FRES)...
April 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28436695/the-impact-of-childhood-parental-quality-on-mental-health-outcomes-in-older-adults
#4
R A Burns, V Loh, J E Byles, H L Kendig
OBJECTIVE: Parental bonding is cited as a determinant of mental health outcomes in childhood, adolescence and early-mid adulthood. Examination of the long-term impact for older adults is limited. We therefore examine the long-term risk of perceived poor parental bonding on mental health across the lifespan and into early-old age. METHODS: Participants (N = 1255) were aged 60-64 years of age and drawn from the Australian Life Histories and Health study. Quality of parental bonding was assessed with the Parental Bonding Instrument (PBI)...
April 24, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28436021/burning-mouth-syndrome-results-of-screening-tests-for-vitamin-and-mineral-deficiencies-thyroid-hormone-and-glucose-levels-experience-at-mayo-clinic-over-a-decade
#5
Claudia S Morr Verenzuela, Mark D P Davis, Alison J Bruce, Rochelle R Torgerson
BACKGROUND: Burning mouth syndrome (BMS) is a disorder characterized by chronic mouth pain in the absence of objective clinical abnormalities. Vitamin or mineral deficiencies may have a role in BMS, but data regarding the prevalence and relevance of hematinic deficiencies are conflicting. We aimed to determine the frequency of specific laboratory abnormalities in patients with BMS. METHODS: We retrospectively reviewed the results of screening blood tests in patients with BMS at our institution between January 2003 and December 2013...
April 23, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28435821/utilization-of-pfge-as-a-powerful-discriminative-tool-for-the-investigation-of-genetic-diversity-among-mrsa-strains
#6
Solmaz Ohadian Moghadam, Mohammad Reza Pourmand, Masoumeh Douraghi, Samira Sabzi, Parisa Ghaffari
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a significant challenge to the burn patient. The implementation of proper monitoring programs and prompt identification of epidemic MRSA strains are critical to consequently control and eradicate potential outbreaks. This study aimed to define the genetic relatedness of MRSA strains isolated from burn patients by analyzing the large fragments of DNA. METHODS: In this cross-sectional study, 126 pus/wound swabs from skin and soft tissue infections (SSTIs) were collected from inpatients of Shahid Motahari Burn Center (Tehran, Iran) in 2013...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28435812/scientometrics-on-public-health-research-in-iran-increase-of-area-studies-despite-embargoes-a-review-article
#7
REVIEW
Brice Poreau
BACKGROUND: Due to embargoes and sanctions from 1979 until 2015, impact on scientific research in Iran may be critical. Public health is the main example of this burning point. In this paper, the aim was to map the scientific research in public health in Iran until 2014 with area studies as well as networks of countries involved. METHODS: We used bibliographic analyses using VOS viewer software for network analysis during the period 1975-2014. Two databases were used: Web of Science and PubMed...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28435754/establishing-successful-patient-centered-medical-homes-in-rural-hawai-i-three-strategies-to-consider
#8
Melissa Nelson Scribner, Kasey Kehoe
The challenges to healthcare delivery posed by Hawai'i's unique geography, physician shortages, and dispersed population are of particular importance in light of implementing the Affordable Care Act (ACA). This study draws on central goals laid out in the ACA - to decrease costs, increase access, and improve patient outcomes. The use of the Patient-Centered Medical Homes (PCMHs) is a care model that has the potential to meet all three goals. How to identify the most effective way to develop PCMHs in the specific context of Hawai'i is the focus of this study...
March 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28435572/does-excision-of-heterotopic-ossification-of-the-elbow-result-in-satisfactory-patient-rated-outcomes
#9
K N Sandeep, G Suresh, B Gopisankar, N Abhishek, A Sujiv
INTRODUCTION: Treatment of heterotopic ossification (HO) of the elbow is challenging and fraught with complications. Patients who sustain direct trauma to the elbow joint, the central nervous system, and thermal burns are at increased risk for development of HO. There is a paucity of studies and reports on patient's self-evaluation after the excision of the heterotopic ossification. MATERIALS AND METHODS: This retrospective study assessed outcomes after excision of heterotopic ossification around the elbow in a cohort of ten patients operated from 2012 to 2015...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435478/disseminated-extrafacial-rosacea-with-papulonecrotic-lesions
#10
Toshio Demitsu, Rieko Tsukahara, Naoka Umemoto, Satoshi Nakamura, Kazutaka Nagashima, Tomoko Yamada, Maki Kakurai, Yoshiaki Tanaka, Akihiro Kakehashi, Toshiko Miyata
BACKGROUND: Rosacea is a common skin disease and predominantly affects on the face of middle-aged women. It exceptionally occurs on the extrafacial areas such as ear, neck, axilla, and upper extremities, and has been reported as disseminated rosacea. MAIN OBSERVATION: A 40-year-old Japanese female presented with one-month history of erythematous skin eruption with burning sensation on the face, neck, and upper limbs. Physical examination showed rosacea-like eruption on the face as well as multiple papules disseminated on the neck, forearms, and hands...
December 31, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28435216/pain-perception-description-after-advanced-surface-ablation
#11
Eva M Sobas, Sebastián Videla, Amanda Vázquez, Itziar Fernández, Miguel J Maldonado, José-Carlos Pastor
PURPOSE: The objective of this study was to characterize the evolution of ocular pain after advanced surface ablation (ASA) to improve strategies in postoperative pain management. METHODS: This was a multicenter, prospective, descriptive, cohort study. The inclusion criteria were healthy individuals ≥18 years old receiving bilateral alcohol-assisted surface ablation with epithelial removal. Pain intensity was evaluated with the visual analog scale (VAS) and the numeric pain rating scale before and after surgery...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28435155/contribution-of-mucus-concentration-and-secreted-mucins-muc5ac-and-muc5b-to-the-pathogenesis-of-muco-obstructive-lung-disease
#12
A Livraghi-Butrico, B R Grubb, K J Wilkinson, A S Volmer, K A Burns, C M Evans, W K O'Neal, R C Boucher
No abstract text is available yet for this article.
May 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/28434399/the-next-generation-of-immunotherapy-keeping-lung-cancer-in-check
#13
REVIEW
Ashwin Somasundaram, Timothy F Burns
Lung cancer is the deadliest malignancy with more cancer deaths per year than the next three cancers combined. Despite remarkable advances in targeted therapy, advanced lung cancer patients have not experienced a significant improvement in mortality. Lung cancer has been shown to be immunogenic and responsive to checkpoint blockade therapy. Checkpoint signals such as CTLA-4 and PD-1/PD-L1 dampen T cell activation and allow tumors to escape the adaptive immune response. Response rates in patients with pretreated, advanced NSCLC were much higher and more durable with PD-1 blockade therapy compared to standard-of-care, cytotoxic chemotherapy...
April 24, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28434250/rolling-tobacco-in-banana-leaves-newspaper-or-copybook-paper-associated-with-significant-reduction-in-lung-function-in-vanuatu
#14
Charles A Weitz, Kathryn M Olszowy, Kelsey N Dancause, Cheng Sun, Alysa Pomer, Howard Silverman, G Lee, Len Tarivonda, Chim W Chan, Akira Kaneko, J K Lum, Ralph M Garruto
In addition to the widespread availability of packaged cigarettes, the inhabitants of island nations of the Southwest Pacific frequently smoke commercially available loose tobacco using manufactured rolling papers, as well as locally grown tobacco rolled in manufactured rolling paper or wrapped in leaves, copybook paper, and newspaper. In this study, Vanuatu men who smoked local tobacco rolled in leaves, copybook paper, or newspaper showed significantly lower forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and FEV1/FVC ratios than men who smoked packaged cigarettes, store-bought tobacco rolled in manufactured rolling paper, or who smoked locally grown tobacco rolled in manufactured rolling papers...
April 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28434157/general-practitioner-attitudes-towards-prescribing-aspirin-to-carriers-of-lynch-syndrome-findings-from-a-national-survey
#15
Samuel G Smith, Robbie Foy, Jennifer McGowan, Lindsay C Kobayashi, John Burn, Karen Brown, Lucy Side, Jack Cuzick
A dose non-inferiority study comparing 100 mg, 300 mg and 600 mg of aspirin for cancer prevention among Lynch Syndrome carriers is underway (Colorectal Adenoma/Carcinoma Prevention Programme trial 3, CaPP3). To guide implementation of the findings, we investigated general practitioner (GP) attitudes towards aspirin prescribing for Lynch Syndrome carriers. We surveyed 1007 UK GPs (9.6% response rate). Using a within-subjects design, GPs read a statement on harms and benefits of aspirin and indicated their willingness to prescribe aspirin at three doses (100 mg, 300 mg, 600 mg)...
April 22, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28433819/environmentally-and-economically-efficient-utilization-of-coal-processing-waste
#16
Margarita A Dmitrienko, Pavel A Strizhak
High concentrations of hazardous anthropogenic emissions (sulfur, nitrogen and carbon oxides) from solid fuel combustion in coal burning plants cause environmental problems that have been especially pressing over the last 20-30 years. A promising solution to these problems is a switch from conventional pulverized coal combustion to coal-water slurry fuel. In this paper, we pay special attention to the environmental indicators characterizing the combustion of different coal ranks (gas, flame, coking, low-caking, and nonbaking coals) and coal-water slurry fuels based on the coal processing waste - filter cakes...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28433763/biomass-burning-sources-and-their-contributions-to-the-local-air-quality-in-hong-kong
#17
K L Chan
In this paper, we present a quantitative estimation of the impacts of biomass burning emissions from different source regions to the local air quality in Hong Kong in 2014 using global chemistry transport model simulations, sun photometer measurements, satellite observations and local monitoring network data. This study focuses on two major biomass burning pollutants, black carbon aerosols and carbon monoxide (CO). The model simulations of atmospheric black carbon and CO show excellent agreement with sun photometer aerosol optical depth (AOD) measurements, satellite CO columns observations and local monitoring stations data...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28433617/induced-and-controlled-dietary-ketosis-as-a-regulator-of-obesity-and-metabolic-syndrome-pathologies
#18
Madeline K Gibas, Kelly J Gibas
A worsening epidemic of diabetes and its precursor, metabolic syndrome (MetS) is engulfing America. A healthy individual, with proper glucose regulation has an ability to switch between burning fat and carbohydrates. It has been suggested that signaling errors within this homeostatic system, characterized by impaired switching of substrate oxidation from glucose to fat in response to insulin, can contribute to the etiology of metabolic syndrome and occurs before the development of type II diabetes. Glucose regulation with restored insulin sensitivity facilitated through clinically regulated, benign dietary ketosis (BDK), may significantly reduce, regulate and reverse the adverse pathologies common to MetS and obesity...
March 28, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28433345/the-effect-of-pre-existing-malnutrition-on-pediatric-burn-mortality-in-a-sub-saharan-african-burn-unit
#19
Joanna Grudziak, Carolyn Snock, Stephen Mjuweni, Jared Gallaher, Bruce Cairns, Anthony Charles
INTRODUCTION: Nutritional status predicts burn outcomes in the developed world, but its effect on burn mortality in the developing world has not been widely studied. In sub Saharan Africa, burn is primarily a disease of children, and the majority of children in sub-Saharan Africa are malnourished. We therefore sought to determine the prevalence and effect of malnutrition on burn mortality at our institution. METHODS: This is a retrospective review of children aged 0-5, with anthropomorphic measurements available, who were admitted to our burn unit from July 2011 to May 2016...
April 19, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28432864/plutonium-in-the-atmosphere-a-global-perspective
#20
REVIEW
P Thakur, H Khaing, S Salminen-Paatero
A number of potential source terms have contributed plutonium isotopes to the atmosphere. The atmospheric nuclear weapon tests conducted between 1945 and 1980 and the re-entry of the burned SNAP-9A satellite in 1964, respectively. It is generally believed that current levels of plutonium in the stratosphere are negligible and compared with the levels generally found at surface-level air. In this study, the time trend analysis and long-term behavior of plutonium isotopes ((239+240)Pu and (238)Pu) in the atmosphere were assessed using historical data collected by various national and international monitoring networks since 1960s...
April 19, 2017: Journal of Environmental Radioactivity
keyword
keyword
130
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"