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Early pregnancy management

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https://www.readbyqxmd.com/read/29154728/neuromyelitis-optica-spectrum-disorders-and-pregnancy-interactions-and-management
#1
Eslam Shosha, Sean J Pittock, Eoin Flanagan, Brian G Weinshenker
Neuromyelitis optica spectrum disorders (NMOSD) predominantly affect women who are of childbearing age. Understanding the interactions between pregnancy and NMOSD is important for clinical management. Aquaporin-4 (AQP4), the most common target antigen in NMOSD, is expressed on placenta in early pregnancy. A variety of immune and cytokine changes in pregnancy may impact pregnancy outcomes in NMOSD patients. Relapses continue during pregnancy and increase in frequency postpartum. Preeclampsia and fetal loss are more frequent in NMOSD than in controls...
December 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29153682/home-blood-pressure-measurement-in-women-with-pregnancy-related-hypertensive-disorders
#2
Patrick G Lan, Jon Hyett, Adrian G Gillin
OBJECTIVES: To determine if home blood pressure measurement (HBPM) provides comparable results to clinic blood pressure (BP) measurement. STUDY DESIGN: A prospective, single-centre study of 37 pregnant and early post-partum women with a hypertensive pregnancy or at high-risk of developing a hypertensive pregnancy were asked to perform HBPM for a minimum period of one week. This was subsequently compared to clinic BP measurement both before and after the period of home measurement...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153671/longitudinal-evaluation-of-uterine-perfusion-endothelial-function-and-central-blood-flow-in-early-onset-pre-eclampsia
#3
Ludmila Barcelos Porto, Augusto Henriques Fulgêncio Brandão, Henrique Vítor Leite, Antônio Carlos Vieira Cabral
OBJECTIVES: Physiopathological mechanisms that trigger clinical manifestations in pre-eclampsia (PE) remain unclear, and management is still a challenge. The identification of tools to predict the onset of the disease and prevent its complications is of great interest in medical practice. The present study aims to evaluate uterine perfusion, endothelial function and central nervous system blood flow in pregnant women with high-risk factors for PE, for comparison of the results between the group of patients who developed early onset PE and those who remained normotensive throughout pregnancy...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153166/a-100-year-review-practical-female-reproductive-management
#4
J S Stevenson, J H Britt
Basic knowledge of mechanisms controlling reproductive processes in mammals was limited in the early 20th century. Discoveries of physiologic processes and mechanisms made early in the last century laid the foundation to develop technologies and programs used today to manage and control reproduction in dairy cattle. Beyond advances made in understanding of gonadotropic support and control of ovarian and uterine functions in basic reproductive biology, advancements made in artificial insemination (AI) and genetics facilitated rapid genetic progress of economically important traits in dairy cattle...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29150302/skin-advanced-glycation-content-reflects-vaginal-tissue-glycation-level-in-relation-to-pregnancy
#5
Homayemem Weli, Jason Cooper, Ying Yang
A few studies have revealed that the advanced glycation content of the vaginal wall in pelvic organ prolapse tissues is elevated. This elevation makes advanced glycation a significant association with the disease. Early detection of vaginal wall glycation could therefore be relevant in the prevention and management of pelvic organ prolapse. A vaginal wall biopsy to detect this would be ideal, but is invasive. Therefore the use of a more accessible organ to access, such as skin, would be beneficial. Our previous independent study suggests that conditions such as pregnancy, can induce a change in the vaginal tissues' glycation content...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29150237/-maternal-deaths-due-to-amniotic-fluid-embolism-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#6
E Morau, A Proust, J-C Ducloy
Amniotic fluid embolism (AFE) is an unpredictable, dreadful complication of pregnancy or childbirth. EA typically includes in the same lapse of time respiratory, haemodynamic, neurological and hemorrhagic symptoms (from early and severe coagulopathy). Immediate supportive treatment by a multidisciplinary team is the cornerstone of the management. Between 2010 an 2012 in France, 24 deaths were related to AFE giving a maternal mortality ratio of 1/100,000 live births (CI 95% 0.6-1.4). AFE ranks as the second leading cause of direct maternal death...
November 14, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29141675/delayed-initiation-of-antenatal-care-and-associated-factors-in-ethiopia-a-systematic-review-and-meta-analysis
#7
REVIEW
Gezahegn Tesfaye, Deborah Loxton, Catherine Chojenta, Agumasie Semahegn, Roger Smith
BACKGROUND: Antenatal care uptake is among the key indicators for monitoring the progress of maternal outcomes. Early initiation of antenatal care facilitates the timely management and treatment of pregnancy complications to reduce maternal deaths. In Ethiopia, antenatal care utilization is generally low, and delayed initiation of care is very common. We aimed to systematically identify and synthesize available evidence on delayed initiation of antenatal care and the associated factors in Ethiopia...
November 15, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29133363/prevalence-of-hypertensive-phenotypes-after-preeclampsia-a-prospective-cohort-study
#8
Agnès Ditisheim, Grégoire Wuerzner, Belen Ponte, Yvan Vial, Olivier Irion, Michel Burnier, Michel Boulvain, Antoinette Pechère-Bertschi
Preeclampsia is associated with increased cardiovascular and renal risk. The aim of this prospective cohort study was to characterize the early postpartum blood pressure (BP) profile after preeclampsia. We enrolled 115 women with preeclampsia and 41 women with a normal pregnancy in a prospective cohort study. At 6 to 12 week postpartum, we assessed the prevalence of different hypertensive phenotypes using 24-hour ambulatory BP monitoring (ABPM), as well as the risk of salt sensitivity and the variability of BP derived from ABPM parameters...
November 13, 2017: Hypertension
https://www.readbyqxmd.com/read/29117431/food-allergy-and-atopic-dermatitis-prediction-progression-and-prevention
#9
REVIEW
Carla Mastrorilli, Carlo Caffarelli, Karin Hoffmann-Sommergruber
The rising burden of allergic diseases in childhood requires a compelling need to identify individuals at risk for atopy very early in life or even predict the onset of food allergy and atopic dermatitis since pregnancy. The development and clinical phenotypes of atopic diseases in childhood depends on a complex interaction between genetic and environmental factors, such as allergen exposure, air pollution and infections. Preventive strategies may include avoidance measures, diet supplements and early complementary food introduction...
November 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29116396/length-of-stay-for-childbirth-in-trentino-north-east-of-italy-the-impact-of-maternal-characteristics-and-organizational-features-of-the-maternity-unit-on-the-probability-of-early-discharge-of-healthy-term-infants
#10
Riccardo Pertile, Lucia Pavanello, Massimo Soffiati, Laura Manica, Silvano Piffer
Early discharge (ED) of healthy term infants has become a common practice due to current social and economic needs. The primary objective of the present study was to evaluate trends in early discharge of healthy term neonates (≥ 37 gestational weeks) by delivery method (cesarean and vaginal) in maternity units in the Province of Trento. The secondary objective was to identify the socio-demographic characteristics (including the area of residence and distance from the designated hospital) and clinical characteristics of mothers whose infants were discharged early...
November 7, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29110978/mumps-an-emergency-medicine-focused-update
#11
Chelsea Bockelman, Thomas C Frawley, Brit Long, Alex Koyfman
BACKGROUND: Mumps is a Paramyxoviridae virus. This disease was rampant prior to introduction of the measles, mumps, and rubella vaccine, resulting in decreased incidence. This disease has demonstrated several outbreaks. OBJECTIVE: This review provides a focused evaluation of mumps, an update on outbreaks, management recommendations, and ways to decrease transmission. DISCUSSION: Clusters of mumps outbreaks continue to occur. The virus is a paramyxovirus, a single-stranded RNA virus...
October 27, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29109107/web-based-social-media-intervention-to-increase-vaccine-acceptance-a-randomized-controlled-trial
#12
Jason M Glanz, Nicole M Wagner, Komal J Narwaney, Courtney R Kraus, Jo Ann Shoup, Stanley Xu, Sean T O'Leary, Saad B Omer, Kathy S Gleason, Matthew F Daley
BACKGROUND: Interventions to address vaccine hesitancy and increase vaccine acceptance are needed. This study sought to determine if a Web-based, social media intervention increases early childhood immunization. METHODS: A 3-arm, randomized controlled trial was conducted in Colorado from September 2013 to July 2016. Participants were pregnant women, randomly assigned (3:2:1) to a Web site with vaccine information and interactive social media components (VSM), a Web site with vaccine information (VI), or usual care (UC)...
November 6, 2017: Pediatrics
https://www.readbyqxmd.com/read/29108060/effect-of-dried-distiller-s-grains-plus-solubles-in-postpartum-diets-of-beef-cows-on-reproductive-performance-of-dam-and-heifer-progeny
#13
E G Taylor, R P Lemenager, V Fellner, K R Stewart
Forty-eight primiparous and multiparous cows were fed a silage-based total mixed ration (TMR; CON), a TMR with 2.5 kg/d DM dried distiller's grains plus solubles (DDGS; MID), or a TMR with 4.7 kg/d DM DDGS (HIGH) from 8.5 ± 4 to 116 ± 4 d postpartum (DPP). All diets were formulated to be isocaloric for a postpartum ADG targeted at 0.22 kg, whereas CP exceeded requirements in both diets containing DDGS. Blood samples were collected from dams at 7- and 21-d intervals for progesterone concentration (resumption of cyclicity) and plasma urea nitrogen, respectively...
October 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/29103725/association-of-immediate-postpartum-plasma-calcium-concentration-with-early-lactation-clinical-diseases-culling-reproduction-and-milk-production-in-holstein-cows
#14
R C Neves, B M Leno, M D Curler, M J Thomas, T R Overton, J A A McArt
The objective of this study was to evaluate the association of postpartum plasma Ca concentration with early-lactation disease outcomes, culling within 60 d in milk, pregnancy to first service, and milk production. A total of 1,453 cows from 5 commercial dairy farms in New York State were enrolled in a prospective cohort study from February to November 2015. Blood samples were collected within 12 h of parturition, and plasma was submitted to a diagnostic laboratory for total Ca measurement. Early-lactation disease, reproductive performance, and milk production from Dairy Herd Improvement Association (DHIA) test-day data were compiled from each farm's management software...
November 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29102365/pregnancy-in-women-with-a-cardiomyopathy-outcomes-and-predictors-from-a-retrospective-cohort
#15
Gilles Billebeau, Martin Etienne, Riadh Cheikh-Khelifa, Daniele Vauthier-Brouzes, Estelle Gandjbakhch, Richard Isnard, Jacky Nizard, Michel Komajda, Marc Dommergues, Philippe Charron
BACKGROUND: Pregnancies in women with pre-existing cardiomyopathies are considered at high risk for complications. However, few data are available to characterize their natural history and predict the outcome. AIMS: Our aim was to evaluate the prevalence and predictors of acute cardiac and obstetric events in women with a cardiomyopathy during pregnancy, excluding peripartum cardiomyopathy. METHODS: In this retrospective study in a referral centre for cardiomyopathies, we included 43 consecutive pregnancies in 36 women with dilated, hypertrophic, arrhythmogenic right ventricular or tachycardia-induced cardiomyopathy, or left ventricular non-compaction...
October 25, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29101866/the-relationship-between-antenatal-body-attitudes-pre-pregnancy-body-mass-index-and-gestational-weight-gain
#16
Bianca Andrews, Briony Hill, Helen Skouteris
OBJECTIVES: an estimated 50% of women experience excessive gestational weight gain (GWG). Maternal body attitudes are associated with GWG, however this relationship is complex and may differ based on pre-pregnancy body mass index (BMI) or gestational age. The aim of this study was to explore the moderating role of maternal pre-pregnancy BMI on the relationship between body attitudes in early-to-mid and late pregnancy and GWG. DESIGN/PARTICIPANTS: pregnant women less than 18 weeks gestation were recruited for a postal questionnaire study via Australian pregnancy online forums, pregnancy and parenting magazines, and antenatal clinics...
October 17, 2017: Midwifery
https://www.readbyqxmd.com/read/29101756/percutaneous-nephrolithotomy-during-early-pregnancy-in-urgent-situations-is-it-feasible-and-safe
#17
Mohammad Mehdi Hosseini, Abbas Hassanpour, Ali Eslahi, Leila Malekmakan
PURPOSE: Urolithiasis during pregnancy poses risks for mother and the fetus with specific challenges in diagnosis and management. We report our experience with urgent percutaneous nephrolithotomy (PCNL) in seven pregnant patients with symptomatic renal stone in early pregnancy. MATERIALS AND METHODS: Seven pregnant patients with symptomatic renal stones were reviewed. The technique comprised PCNL with complete access under guide of ultrasonography in prone position under general anesthesiausing pneumatic lithoclast for stone fragmentation...
November 4, 2017: Urology Journal
https://www.readbyqxmd.com/read/29097507/noninvasive-prenatal-diagnosis-of-single-gene-disorders-by-use-of-droplet-digital-pcr
#18
Joan Camunas-Soler, Hojae Lee, Louanne Hudgins, Susan R Hintz, Yair J Blumenfeld, Yasser Y El-Sayed, Stephen R Quake
BACKGROUND: Prenatal diagnosis in pregnancies at risk of single-gene disorders is currently performed using invasive methods such as chorionic villus sampling and amniocentesis. This is in contrast with screening for common aneuploidies, for which noninvasive methods with a single maternal blood sample have become standard clinical practice. METHODS: We developed a protocol for noninvasive prenatal diagnosis of inherited single-gene disorders using droplet digital PCR from circulating cell-free DNA (cfDNA) in maternal plasma...
November 2, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29096284/psychosocial-predictors-of-gestational-weight-gain-and-the-role-of-mindfulness
#19
Jeni Matthews, Jennifer Huberty, Jenn Leiferman, Matthew Buman
OBJECTIVE: To identify the psychosocial factors (i.e., stress, anxiety, depression, social support) that are associated with gestational weight gain (GWG) and the relationship of mindfulness with GWG during each trimester of pregnancy. DESIGN: In this cross-sectional study, an online survey that assessed physical and mental health and wellness practices was administered to pregnant women. PARTICIPANTS: Pregnant women ≥8 weeks gestation, ≥18 years old, and could read and write in English...
October 16, 2017: Midwifery
https://www.readbyqxmd.com/read/29094753/antenatal-haemoglobin-a1c-centiles-does-one-size-fit-all
#20
Ruth C E Hughes, Jonathan A Williman, Joanna E Gullam
BACKGROUND: In New Zealand, haemoglobin A1c measurements are routinely offered at booking, preferably before 20 weeks gestation, to detect pre-existing hyperglycaemia. A haemoglobin A1c <5.9% (41 mmol/mol) is considered normal based on the reference range for the non-pregnant population. AIMS: To determine pregnancy-specific haemoglobin A1c centiles by gestation and ethnicity. MATERIALS AND METHODS: This is a population-based observational study of pregnancies uncomplicated by diabetes (pre-existing or gestational) with ≥1 haemoglobin A1c measurement...
November 2, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
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