keyword
https://read.qxmd.com/read/38537218/intense-psma-uptake-in-solitary-fibrous-tumor-of-the-seminal-vesicle
#1
JOURNAL ARTICLE
Qian Zhao, Aisheng Dong, Huamao Ye, Changjing Zuo
Solitary fibrous tumor arising from the seminal vesicle is very rare. We describe 18F-PSMA-1007 PET/CT findings in a case of prostate adenocarcinoma with a solitary fibrous tumor of the left seminal vesicle. The solitary fibrous tumor showed intense 18F-PSMA-1007 uptake mimicking metastatic prostate adenocarcinoma. This case indicates that solitary fibrous tumor may cause false-positive result when using PSMA PET in staging of prostate cancer.
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537213/occult-smarca4-deficient-undifferentiated-carcinoma-unmasked-by-68ga-fapi-46-pet-ct
#2
JOURNAL ARTICLE
Weizhi Xu, Long Zhao, Jiayu Cai, Haojun Chen
SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are rare and aggressive neoplasms commonly found in male smokers and portend a poor prognosis. In this case, we reported 18F-FDG and 68Ga-FAPI-46 PET/CT findings in an occult SMARCA4-dUT located in the left pulmonary hilum along with mediastinal lymph node metastases. 68Ga-FAPI-46 PET/CT showed superiority over 18F-FDG for detecting SMARCA4-dUT lesions. This case highlighted that 68Ga-FAPI-46 PET/CT may be a promising imaging modality in the evaluation of SMARCA4-dUT, particularly for detecting the occult SMARCA4-dUT arising in uncommon sites...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537210/treatment-of-bone-metastases-of-breast-cancer-with-177lu-dota-iba
#3
JOURNAL ARTICLE
Jia Deng, Jian Yang, Zixuan Cheng, Yue Chen
Bone metastasis of breast cancer often presents as osteolytic. 177Lu-DOTA-ibandronic acid (177Lu-DOTA-IBA) is a new radioactive drug for bone metastasis lesion. We report a case of recurrent intermittent pain due to bone metastasis, who demonstrated a satisfactory therapy response after 2 cycles of 177Lu-DOTA-IBA. In addition, the patient did not have any observable adverse effects.
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537208/68ga-fapi-pet-ct-in-an-interesting-case-of-metastatic-pulmonary-meningioma
#4
JOURNAL ARTICLE
Priyavrat Purohit, Bhagwant Rai Mittal, Rajender Kumar, Harmandeep Singh, Jaya Shukla, Amanjit Bal, Navneet Singh
Meningiomas are one of the major primary CNS tumors. Most meningiomas are benign, but rarely, these metastasize to distant organs, the lungs being the commonest site of metastasis. 18F-FDG PET/CT has been used to evaluate metastatic pulmonary meningioma. However, 68Ga-FAPI PET/CT has not yet been evaluated. The present case highlights the 68Ga-FAPI uptake in metastatic pulmonary meningioma in a postoperated case of left tentorial meningioma presenting with lung masses. Image-guided biopsy from the lung mass was consistent with metastatic meningioma...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537207/unusual-metastasis-of-signet-ring-cell-gastric-cancer-that-could-not-be-detected-with-18f-fdg-pet-but-with-68ga-fapi-pet-ct
#5
JOURNAL ARTICLE
Murat Yilmaz Kiran, Leman Damla Ercan, Ecem Karatay, Duygu Has Simsek, Yasemin Sanli
A 70-year-old man who was scheduled for surgery because of the recurrence of gastric cancer was referred to our clinic preoperatively. The patient underwent a comprehensive evaluation through 18F-FDG and 68Ga-FAPI (68Ga-labeled FAP inhibitors) PET/CT scans. The 68Ga-FAPI PET/CT scan was particularly valuable in this case because of its ability to detect recurrent mass lesions and identify unusual metastatic sites compared with the 18F-FDG PET/CT scan.
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537205/18f-fet-pet-ct-in-calcifying-pseudoneoplasm-of-the-neuraxis-first-case
#6
JOURNAL ARTICLE
Demetrio Aricò, Giulia Giacoppo, Michelangelo Bambaci, Lorenza Marino, Andrea Girlando, Giuseppe Sortino, Giorgia Leone, Bethania Fernandes, Marco Alì, Laura Evangelista, Alberto Romano
A 66-year-old man has been treated in a psychiatric department for 4-5 years for a depressive syndrome, which is associated with poor motor initiative, confusional state, and dysosmia. Dynamic 18F-FET PET/CT showed only faint uptake of radiotracer just above the background on the left frontal calcific lesion. The time-activity curve of the neoplasms showed a descending pattern. After a left fronto-orbitary minicraniotomy surgery, histology examination concluded for a rare calcifying pseudoneoplasm of the neuraxis (CAPNON)...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537204/18f-fdg-pet-ct-in-lupus-enteritis-presenting-with-fever-and-abdominal-pain
#7
JOURNAL ARTICLE
Komal Preet, Bhagwant Rai Mittal, Harmandeep Singh, Rajender Kumar, Aravind Sekar, Kailash Kurdia
Systemic lupus erythematosus is a systemic autoimmune disease associated with various manifestations. Here, we report a compelling case of a 42-year-old woman who presented with lupus enteritis as a sole manifestation of systemic lupus erythematosus and underwent 18F-FDG PET/CT. The resected bowel segment revealed vasculitis, and subsequent workup revealed positive antinuclear and anti-double-stranded antibody levels, confirming lupus enteritis, thus highlighting the diagnostic role of 18F-FDG PET/CT in reaching the final diagnosis...
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38537076/clinical-outcomes-in-patients-with-traumatic-dehiscence-of-penetrating-keratoplasty-grafts
#8
JOURNAL ARTICLE
Jason Fan, Julia L Hudson, Akaanksh Shetty, Rahul Tonk, Harry W Flynn
PURPOSE: The purpose of this study was to report clinical characteristics and outcomes of surgical repair for patients with traumatic dehiscence of penetrating keratoplasty (PKP) grafts. METHODS: Retrospective, consecutive chart review of patients evaluated at Bascom Palmer Eye Institute between 2015 and 2020 with traumatic dehiscence of penetrating keratoplasty grafts. RESULTS: The study cohort consisted of 65 eyes of 65 patients. The mean age at presentation was 72 years (SD 18), with a male predominance (65%)...
March 27, 2024: Cornea
https://read.qxmd.com/read/38537044/toxoplasmosis-outbreak-in-s%C3%A3-o-paulo-brazil-epidemiology-and-visual-outcome
#9
JOURNAL ARTICLE
Luciana Peixoto Santos Finamor, Geraldine Madalosso, José Eduardo Levi, Yuslay Fernández Zamora, Gabriela Akemi Kamioka, Paula Marinho, Heloisa Nascimento, Cristina Muccioli, Rubens Belfort
PURPOSE: To describe a 2019 acute toxoplasmosis outbreak in the city of São Paulo, Brazil, and to evaluate the laboratory serological profile for toxoplasmosis for three consecutive years. The ophthalmological manifestations of the patients involved in the outbreak were also studied. METHODS: A cross-sectional descriptive study of a toxoplasmosis outbreak in São Paulo, Brazil, between February and May 2019. Epidemiological data were described, as were the observed ocular manifestations...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38537038/novel-optical-coherence-tomography-findings-in-a-patient-with-methanol-toxicity-a-case-report
#10
Burcu Işık, Mehmet Giray Ersoz, Mehmet Dokur, Ismail Yıldız, Mehmet Sami Islamoğlu
We report a case of acute methanol toxicity with unique optical coherence tomography findings. A 56-year-old man was referred to our ophthalmology clinic with a history of handmade vodka consumption and vision loss. On ophthalmologic examination, his vision was 20/100 in his right eye and 20/200 in his left eye. Bilateral mild optic disk hyperemia was detected on fundus examination. Because of the severity of systemic symptoms in such cases, it is very difficult to include optical coherence tomography in the ophthalmologic examination...
2024: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/38536996/perinatal-results-and-long-term-follow-up-of-fetal-cardiac-tumors-a-30-year-historical-cohort-study
#11
JOURNAL ARTICLE
Fabricio Marcondes Camargo, Maria de Lourdes Brizot, Rossana Pulcineli Vieira Francisco, Werther Brunow de Carvalho, Nana Miura Ikari, Stella Verzinhasse Peres, Marco Antônio Borges Lopes, Lilian Maria Lopes
BACKGROUND: This was a 30-year retrospective cohort study that approximates closely to the natural history of cardiac tumors diagnosed in the fetus, since there was no case of pregnancy interruption. OBJECTIVE: To assess morbidity and mortality in the perinatal period and at long term in fetuses diagnosed with cardiac tumor. Our secondary objective was to assess the evaluating factors of perinatal and postnatal results. METHODS: This was a retrospective cohort study with 74 pregnant women with an echocardiographic diagnosis of fetal cardiac tumor at two referral centers between May 1991 and November 2021...
2024: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/38536981/relative-incidence-of-interstitial-lung-diseases-in-brazil
#12
JOURNAL ARTICLE
Simone Lobo Krupok Matias, Carlos Alberto de Castro Pereira, Maria Raquel Soares, Flávia Castro Velasco Fernandes, Maria Auxiliadora Carmo Moreira, Fernanda Maciel de Aguiar Baptista, Tarciane Aline Prata, Gediel Cordeiro Junior, Eliane Viana Mancuzo
OBJECTIVE: To assess the relative frequency of incident cases of interstitial lung diseases (ILDs) in Brazil. METHODS: This was a retrospective survey of new cases of ILD in six referral centers between January of 2013 and January of 2020. The diagnosis of ILD followed the criteria suggested by international bodies or was made through multidisciplinary discussion (MDD). The condition was characterized as unclassifiable ILD when there was no specific final diagnosis following MDD or when there was disagreement between clinical, radiological, or histological data...
2024: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://read.qxmd.com/read/38536952/familial-recurrence-of-incontinentia-pigmenti-due-to-de-novo-pathogenic-variants-in-the-ikbkg-gene
#13
Julie Steffann, Judite De Oliveira Santos, Anne-Laure Zelbin, Smail Hadj-Rabia, Fabienne Charbit-Henrion, Florence Petit
Incontinentia pigmenti (IP, Bloch-Sulzberger syndrome) is a multisystem disorder which associates specific skin lesions that evolves in four stages, and occasionally, central nervous system, eye, hair, and teeth involvement. Familial (35%) and sporadic (65%) cases are caused by pathogenic variants in the IKBKG gene. Here we report an unusual family, where, in two half-sisters affected by typical IP, molecular genetic analysis identified a likely pathogenic non-sense variant in the IKBKG gene of one of the sisters, the other being not a carrier...
March 27, 2024: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/38536847/outcome-of-complicated-osteoarticular-brucellosis-in-a-tertiary-care-center-in-saudi-arabia
#14
JOURNAL ARTICLE
Ebrahim Mahmoud, Areej Alaman, Raghad Alsayari, Anadel Hakeem, Mohammad Bosaeed, Azaheer Ibrahim, Saleh Algazlan, Abdullah Almanea, Ahmed A Abulaban
OBJECTIVE: To evaluate the outcome of complicated osteoarticular brucellosis. METHODS: A retrospective chart review was conducted at King Abdulaziz Medical City (KAMC), in Riyadh, Saudi Arabia. All patients aged more than 14 who have been diagnosed with complicated brucellosis with osteoarticular disease between July 2016 and December 2022 were included. RESULTS: A total of 82 (10.7%) patients met the criteria, with a male predominance of 66 (80...
2024: PloS One
https://read.qxmd.com/read/38536822/immediate-postnatal-prediction-of-death-or-bronchopulmonary-dysplasia-among-very-preterm-and-very-low-birth-weight-infants-based-on-gradient-boosting-decision-trees-algorithm-a-nationwide-database-study-in-japan
#15
JOURNAL ARTICLE
Kota Yoneda, Tomohisa Seki, Yoshimasa Kawazoe, Kazuhiko Ohe, Naoto Takahashi
INTRODUCTION: Bronchopulmonary dysplasia (BPD) poses a substantial global health burden. Individualized treatment strategies based on early prediction of the development of BPD can mitigate preterm birth complications; however, previously suggested predictive models lack early postnatal applicability. We aimed to develop predictive models for BPD and mortality based on immediate postnatal clinical data. METHODS: Clinical information on very preterm and very low birth weight infants born between 2008 and 2018 was extracted from a nationwide Japanese database...
2024: PloS One
https://read.qxmd.com/read/38536759/risk-factors-and-characteristics-analysis-of-cognitive-impairment-in-patients-with-cerebral-infarction-during-recovery-period
#16
JOURNAL ARTICLE
Yan Li, Wenjuan Geng, Xiaomeng Zhang, Baobin Mi
Objective: To analyze the risk factors and characteristics of cognitive impairment in patients with cerebral infarction during the recovery period. Methods: This retrospective case-control study included 183 patients with cerebral infarction in the recovery period. According to the MMSE score, they were divided into a cognitive impairment group of 79 cases and a cognitive normal group of 104 cases. Collect clinical data from all patients, including age, gender, body mass index, laboratory test results, past medical history, National Institute of Health Stroke Scale (NIHSS) score, modified Barthel index, Oxfordshire Community Stroke Project (OCSP) classification, and number of infarcted lesions...
March 27, 2024: International Journal of Neuroscience
https://read.qxmd.com/read/38536723/unveiling-new-patterns-a-surgical-deep-learning-model-for-intestinal-obstruction-management
#17
JOURNAL ARTICLE
Ozan Can Tatar, Mustafa Alper Akay, Elif Tatar, Semih Metin
BACKGROUND: Swift and accurate decision-making is pivotal in managing intestinal obstructions. This study aims to integrate deep learning and surgical expertise to enhance decision-making in intestinal obstruction cases. METHODS: We developed a deep learning model based on the YOLOv8 framework, trained on a dataset of 700 images categorised into operated and non-operated groups, with surgical outcomes as ground truth. The model's performance was evaluated through standard metrics...
February 2024: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://read.qxmd.com/read/38536716/scratching-beneath-the-surface-an-evaluation-of-the-management-of-scabies-2017-2023
#18
JOURNAL ARTICLE
Bryony Broster, Amanda Clarke, Collins Iwuji, Suneeta Soni
INTRODUCTION: Possible resistance to recommended treatments for scabies has emerged recently. In response to anecdotal reports of a recent increase in treatment failure with permethrin, the British Association for Sexual Health and HIV (BASHH) released a statement alerting members to this. AIMS: To examine attendances and the treatment pathways for scabies cases seen at local sexual health clinics. METHODOLOGY: A case note review of scabies attendances between January 2017 and December 2023 was conducted...
March 27, 2024: International Journal of STD & AIDS
https://read.qxmd.com/read/38536654/surgical-technique-proximal-extension-of-instrumentation-using-sublaminar-bands-for-salvage-of-postoperative-proximal-junctional-failure-in-pediatric-patients
#19
JOURNAL ARTICLE
Mason A Fawcett, Richard M Schwend
PURPOSE: Proximal junctional failure is a complication that can occur following posterior spine surgery with instrumentation. The ability to surgically revise this complication is important for the spine surgeon, yet there is little literature on the topic, especially for pediatric patients. METHODS: The technique we describe involves proximal extension of the existing instrumentation using paired levels of sublaminar bands that allows for a smooth transition of forces at the junction of instrumented and non-instrumented regions of the spine...
March 27, 2024: Spine Deformity
https://read.qxmd.com/read/38536628/evaluation-of-the-histologic-and-immunohistochemical-cd34-glutamine-synthetase-findings-in-idiopathic-non-cirrhotic-portal-hypertension-incph
#20
JOURNAL ARTICLE
Melek Büyük, Neslihan Berker, Doğu Vurallı Bakkaloğlu, İbrahim Volkan Şenkal, Zerrin Önal, Mine Güllüoğlu
AIM: Idiopathic non-cirrhotic portal hypertension (INCPH) is a vascular disorder of uncertain origin. Diagnosis can be challenging on liver biopsy. Despite diverse histomorphologic findings documented in literature, studies on the frequency of these findings are lacking. This study aims to assess both the histomorphologic features and the immunoexpression patterns of CD34 and glutamine synthetase (GS) in liver biopsies and searched for their contribution to the pathologic diagnosis of INCPH...
March 27, 2024: Hepatology International
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