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https://www.readbyqxmd.com/read/29779613/facial-plastic-surgery-in-the-geriatric-population
#1
REVIEW
Ian Newberry, Eric W Cerrati, J Regan Thomas
Greater life expectancy with advancements in technology and medicine has led to an increasing interest in facial rejuvenation. Facial aging is an inevitable process that largely results from soft tissue descent and volumetric deflation. However, a comprehensive knowledge of the aging process and precise assessment of the exact pathologies yielding the patient's senescent appearance is essential to produce the best cosmetic outcome. The surgeon must evaluate each region independently and the aging face as a whole to ensure a pleasing, natural appearance...
May 17, 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29764162/the-evolving-role-of-immune-oncology-in-colorectal-cancer
#2
Shaheenah Dawood
Metastatic colorectal cancer still remains an essentially non curable disease. However, with advances in chemotherapeutic and personalizing therapeutic approaches with the incorporation of targeted therapy such as anti-EGFR and anti-VEGF agents survival associated with metastatic colorectal cancer has certainly improved over the last two decades. Patients who are not amenable to surgery median survival remain approximately 2 to 3 years. In an attempt to improve prognostic outcome over the last decade research has focused on therapeutic options geared towards harnessing the immune system with success observed with the use of immune checkpoint inhibitors in the realm of a number of solid tumors including lung and renal cancer...
April 2018: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/29742860/essential-anatomy-of-the-anorectum-for-colorectal-surgeons-focused-on-the-gross-anatomy-and-histologic-findings
#3
REVIEW
Jong Min Lee, Nam Kyu Kim
The anorectum is a region with a very complex structure, and surgery for benign or malignant disease of the anorectum is impossible without accurate anatomical knowledge. The conjoined longitudinal muscle consists of smooth muscle from the longitudinal muscle of the rectum and the striate muscle from the levator ani and helps maintain continence; the rectourethralis muscle is connected directly to the conjoined longitudinal muscle at the top of the external anal sphincter. Preserving the rectourethralis muscle without damage to the carvernous nerve or veins passing through it when the abdominoperineal resection is implemented is important...
April 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29709331/the-importance-of-lymph-node-ratio-for-patients-with-mandibular-infiltration-of-oral-squamous-cell-carcinoma
#4
Ali-Farid Safi, Martin Kauke, Andrea Grandoch, Hans-Joachim Nickenig, Joachim Zöller, Matthias Kreppel
PURPOSE: Lymph node ratio (LNR) essentially improves assessment of prognosis and therapeutic decision making for patients with oral squamous cell carcinoma, as it considers both the number of positive lymph nodes and the number of dissected lymph nodes. Mandibular infiltration by oral squamous cell carcinoma is a vital clinicopathological feature, significantly worsens prognosis. However, to the best of our knowledge, data on the influence of LNR on prognosis for patients with OSCC and mandibular infiltration are not available...
April 5, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29698405/mining-co-occurrence-and-sequence-patterns-from-cancer-diagnoses-in-new-york-state
#5
Yu Wang, Wei Hou, Fusheng Wang
The goal of this study is to discover disease co-occurrence and sequence patterns from large scale cancer diagnosis histories in New York State. In particular, we want to identify disparities among different patient groups. Our study will provide essential knowledge for clinical researchers to further investigate comorbidities and disease progression for improving the management of multiple diseases. We used inpatient discharge and outpatient visit records from the New York State Statewide Planning and Research Cooperative System (SPARCS) from 2011-2015...
2018: PloS One
https://www.readbyqxmd.com/read/29659161/neurovascular-relations-of-the-trigeminal-nerve-in-asymptomatic-individuals-studied-with-high-resolution-three-dimensional-magnetic-resonance-imaging
#6
Fernando Ruiz-Juretschke, LaíN H González-Quarante, Roberto García-Leal, Vicente Martínez de Vega
Neurovascular compression (NVC) is considered the main cause of classic trigeminal neuralgia (TN) and may be surgically addressed with microvascular decompression (MVD). Preoperative high-resolution three-dimensional magnetic resonance has proven a reliable tool to diagnose NVC in patients with refractory TN undergoing MVD. However, there is still scarce data regarding the rate, degree, and characteristics of neurovascular compression in asymptomatic individuals. This article describes the vascular relations of the trigeminal nerve in the cerebellopontine angle (CPA) in 100 subjects without known TN studied with 3...
April 16, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29628333/multidisciplinary-difficult-airway-course-an-essential-educational-component-of-a-hospital-wide-difficult-airway-response-program
#7
W Robert Leeper, Elliott R Haut, Vinciya Pandian, Sajan Nakka, Jeffrey Dodd-O, Nasir Bhatti, Elizabeth A Hunt, Mustapha Saheed, Nicholas Dalesio, Adam Schiavi, Christina Miller, Thomas D Kirsch, Lauren Berkow
OBJECTIVE: A hospital-wide difficult airway response team was developed in 2008 at The Johns Hopkins Hospital with three central pillars: operations, safety monitoring, and education. The objective of this study was to assess the outcomes of the educational pillar of the difficult airway response team program, known as the multidisciplinary difficult airway course (MDAC). DESIGN: The comprehensive, full-day MDAC involves trainees and staff from all provider groups who participate in airway management...
April 5, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29621061/spontaneous-regression-of-diffuse-periosteal-melanotic-neuroectodermal-tumor-of-infancy-in-the-tibia-with-13-year-follow-up
#8
Li Lei, Brandon D Ellsworth, Lionel W Young, Albert Kheradpour, Craig W Zuppan
Melanotic neuroectodermal tumor of infancy (MNTI) is a rare entity primarily affecting the craniofacial bones during the first year of life, with only 5 reported cases involving peripheral long bones. We herein present a case of MNTI in the tibia of an infant, with a somewhat atypical presentation, and a noteworthy clinical course characterized by progressive spontaneous resolution without therapy, thus sparing the child the trauma of amputation. There is no evidence of active residual or recurrent disease with 13-year follow-up...
April 4, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29616218/recent-insights-into-the-contribution-of-the-changing-hypertrophic-chondrocyte-phenotype-in-the-development-and-progression-of-osteoarthritis
#9
REVIEW
Ellen G J Ripmeester, Ufuk Tan Timur, Marjolein M J Caron, Tim J M Welting
Osteoarthritis (OA) is an extremely prevalent age-related condition. The economic and societal burden due to the cost of symptomatic treatment, inability to work, joint replacement, and rehabilitation is huge and increasing. Currently, there are no effective medical therapies that delay or reverse the pathological manifestations of OA. Current treatment options are, without exception, focused on slowing down progression of the disease to postpone total joint replacement surgery for as long as possible and keeping the associated pain and joint immobility manageable...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29616107/awareness-of-hepatic-arterial-variants-is-required-in-surgical-oncology-decision-making-strategy-case-report-and-review-of-literature
#10
Robert Sitarz, Monika Berbecka, Jerzy Mielko, Karol Rawicz-Pruszyński, Grzegorz Staśkiewicz, Ryszard Maciejewski, Wojciech Polkowski
Surgery for the treatment of pancreatic cancer remains the gold standard, however, the identification of the vascular supply of the pancreas and the nearby organs remains a crucial difficulties in a curative resection. During pancreatic head resection for carcinoma dissection of regional arterial vasculature is mandatory. Normal coeliac and hepatic arterial anatomy occurs in ~50-70% of patients and multiple variations have been described. Knowledge of multiple arterial anomalies is essential in hepato-pancreatico-billary surgery to avoid unnecessary complications...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29615572/the-role-of-hedgehog-signalling-in-the-formation-of-the-ventricular-septum
#11
REVIEW
Antonia Wiegering, Ulrich Rüther, Christoph Gerhardt
An incomplete septation of the ventricles in the vertebrate heart that disturbes the strict separation between the contents of the two ventricles is termed a ventricular septal defect (VSD). Together with bicuspid aortic valves, it is the most frequent congenital heart disease in humans. Until now, life-threatening VSDs are usually treated surgically. To avoid surgery and to develop an alternative therapy (e.g., a small molecule therapy), it is necessary to understand the molecular mechanisms underlying ventricular septum (VS) development...
December 12, 2017: Journal of Developmental Biology
https://www.readbyqxmd.com/read/29613894/metabolic-and-toxic-myelopathies
#12
Robert N Schwendimann
PURPOSE OF REVIEW: Myelopathy may occur as a consequence of various metabolic and toxic conditions. This article provides an update on the clinical presentations, diagnostic evaluations, and management of metabolic and toxic myelopathies. RECENT FINDINGS: Myelopathy and myeloneuropathy due to vitamin B12 deficiency is increasing in prevalence partly because of an aging population. Early recognition of the clinical symptoms and rapid initiation of treatment is essential...
April 2018: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29610626/knowledge-and-awareness-of-medical-practitioners-of-jazan-city-towards-oral-and-maxillofacial-surgery-as-a-specialty
#13
Fareedi Mukram Ali, Ghassan M Al-Iryani, Sultan Mohammed Namis, Asma Ali Hezam, Salma Abdu Swaid, Anas Esam Alomar
BACKGROUND: In many health services communities the scope of oral and maxillofacial surgery (OMFS) as a discipline is frequently not probably understood. Good awareness towards OMFS among different branches of health services providers is essential for better referral strategies and will be for the benefit of the patient. MATERIALS AND METHODS: The cross-sectional study was done using a specially prepared questionnaire distributed randomly to 125 general medical practitioners working in Jazan province...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29600215/tuberculous-tenosynovitis-of-the-wrist-and-the-hand-the-3-anatomo-clinical-forms-described-by-kanavel-about-4-cases
#14
Coulibaly Ndeye Fatou, B A Amadou, Gueye Alioune Badara, Dembele Badara, Daffe Mohamedi, Dieme Charles Bertini
Introduction: Tuberculous tenosynovitis localization is rare. This unusual presentation, often misunderstood, results in frequent misdiagnosis. We report 4 cases of patients which represent the 3 anatomo-clinical forms described by Kanavel. The knowledge of its different manifestations will make it possible to recognize and to suspect the tuberculous origin. Case Report: This was a retrospective study from January 2006 to May 2017 which involved all patients received and treated with tuberculous tenosynovitis...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29581690/mentoring-in-surgery-mentor-parshuram-dronacharya-krishan
#15
REVIEW
Brij B Agarwal, Nayan Agarwal, Neeraj Dhamija, Chintamani
Success in any profession has no well-defined predictors. Knowledge, skills, training, and talent come in plenty but fail at times to achieve the universal goal of success. Some attribute it to luck. Apart from the tangible ingredients of a successful career, the intangibles like luck or something ill-defined is a real challenge. The intangibles seem like a chasm, an abyss, or a phantom obstacle. Presence of a guiding spirit who can handhold you to overcome these is essential for success. The aim of a professional is to learn, earn, and yearn for creativity...
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29579445/a-collaborative-for-implementation-of-an-evidence-based-clinical-pathway-for-enhanced-recovery-in-colon-and-rectal-surgery-in-an-affiliated-network-of-healthcare-organizations
#16
David W Larson, Jenna K Lovely, Jesse Welsh, Sho Annaberdyev, Chris Coffey, Cybil Corning, Bret Murray, Douglas Rose, Lawrence Prabhakar, Marcus Torgenson, Eugene Dankbar, Mark V Larson
BACKGROUND: In 2015 the Mayo Clinic Care Network (MCCN), in an effort to extend medical knowledge and share these best practices, embarked on an education mission to diffuse the clinical practice redesign involving the practice of colon and rectal surgery at Mayo Clinic (Rochester, Minnesota) to members of the MCCN. They elected to use a collaborative framework in an attempt to transfer knowledge to multiple teams in an efficient and supportive manner. METHODS: Eight MCCN members assembled a multidisciplinary team, which participated in both a didactic learning session delivered by frontline experts, as well as follow-up remote sessions regarding Mayo Clinic's enhanced recovery pathway for colon and rectal surgery...
April 2018: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29578875/strategies-for-the-prevention-and-treatment-of-surgical-site-infection-in-the-lumbar-spine
#17
Joseph S Butler, Scott C Wagner, Patrick B Morrissey, Ian D Kaye, Arjun S Sebastian, Gregory D Schroeder, Kristen Radcliff, Alexander R Vaccaro
Surgical site infection (SSI) following spine surgery can be devastating for both the patient and the surgeon. It leads to significant morbidity and associated health care costs, from readmissions, reoperations, and subsequent poor clinical outcomes. Complications associated with SSI following spine surgery include pseudarthrosis, neurological deterioration, sepsis, and death. Its management can be very challenging. The diagnosis of SSI involves the interpretation of combined clinical, laboratory, and occasionally radiologic findings...
March 23, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29574988/effects-of-postoperative-pain-management-educational-interventions-on-the-outcomes-of-parents-and-their-children-who-underwent-an-inpatient-elective-surgery-a-randomised-controlled-trial
#18
Lixia Zhu, Wai Chi Sally Chan, Joanne Li Wee Liam, Chunxiang Xiao, Evelyn Chin Choo Lim, Nan Luo, Kin Fong Karis Cheng, Hong-Gu He
AIM: To examine the effects of a postoperative pain management educational intervention on the outcomes of parents and their children who underwent inpatient elective surgery. BACKGROUND: Equipping parents with knowledge and skills to manage their children's postoperative pains is essential. Very limited studies have examined the effects of educational interventions on parents' knowledge, attitudes and use of pharmacological and non-pharmacological pain relief methods...
March 25, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29557490/anatomy-and-injuries-of-the-pediatric-wrist-beyond-the-basics
#19
REVIEW
Ezekiel Maloney, Andrew M Zbojniewicz, Jie Nguyen, Yu Luo, Mahesh M Thapa
Ligamentous injuries of the pediatric wrist, once thought to be relatively uncommon, are increasingly recognized in the context of acute high-energy mechanism trauma and chronic axial loading, including those encountered in both recreational and high-performance competitive sports. Recent advances in MR-based techniques for imaging the pediatric wrist allow for sensitive identification of these often radiographically occult injuries. Detailed knowledge of the intrinsic and supportive extrinsic ligamentous complexes, as well as normal developmental anatomy and congenital variation, are essential to accurately diagnose injuries to these structures...
March 20, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29541887/how-i-do-it-surgical-clipping-of-vertebrobasilar-junction-aneurysms-through-a-far-lateral-transcondylar-approach
#20
Vladimir Nakov, Toma Spiriev, Evgeni Stavrev
BACKGROUND: Vertebrobasilar junction aneurysms occur rarely, but have a higher rupture rate than supratentoral aneurysms, and higher morbidity and mortality. Their location ventral to the neuroaxis makes them a challenging surgical lesion. METHODS: In this paper, we share our experience with the surgical technique for the management of these complex aneurysms. CONCLUSION: An in-depth understanding of the anatomy of these aneurysms, careful preoperative planning, and a meticulous surgical technique, including knowledge of every detail of the procedure-positioning, an advanced skull base technique, and careful aneurysm dissection and clipping-is essential for a successful outcome of the surgery...
March 14, 2018: Acta Neurochirurgica
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