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Post traumatic stress disorder

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https://www.readbyqxmd.com/read/28551591/evidence-that-anhedonia-is-a-symptom-of-opioid-dependence-associated-with-recent-use
#1
Joshua B B Garfield, Sue M Cotton, Nicholas B Allen, Ali Cheetham, Marni Kras, Murat Yücel, Dan I Lubman
BACKGROUND: Anhedonia is prevalent among substance-dependent populations. The hedonic allostasis model suggests this is due to the effects of addictive substances on neural substrates of reward processing. However, previous research may have been confounded by other factors likely to influence anhedonia, including tobacco use, psychopathology, and history of trauma and other stressors. Thus it remains unclear whether elevated anhedonia in substance-dependent populations is caused by substance use itself, or is due to other correlates of substance dependence...
May 17, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28551590/higher-pretreatment-blood-pressure-is-associated-with-greater-alcohol-drinking-reduction-in-alcohol-dependent-individuals-treated-with-doxazosin
#2
Carolina L Haass-Koffler, Kimberly Goodyear, William H Zywiak, Molly Magill, Sarah E Eltinge, Paul M Wallace, Victoria M Long, Nitya Jayaram-Lindström, Robert M Swift, George A Kenna, Lorenzo Leggio
BACKGROUND: Preclinical and clinical research suggest that the α1 receptor antagonist prazosin reduces alcohol consumption. Furthermore, clinical studies indicate a role for prazosin in treating Post-Traumatic Stress Disorder (PTSD) symptoms and a recent trial suggested that pre-treatment blood pressure (BP) predicts therapeutic response for prazosin in PTSD patients. Whether pre-treatment BP may predict response to α1 blockers in alcohol-dependent (AD) patients is unknown. We previously reported a randomized controlled trial (RCT) where doxazosin, an α1 receptor antagonist with a more favorable pharmacokinetic profile than prazosin, reduced drinks per week (DPW) and heavy drinking days (HDD) in AD patients with a high family history density of alcoholism...
May 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28551446/intimate-partner-violence-and-pregnancy-epidemiology-and-impact
#3
REVIEW
Christian A Chisholm, Linda Bullock, James E Jef Ferguson
Intimate partner violence (IPV) is a significant public health problem in our society, affecting women disproportionately. IPV takes many forms, including physical violence, sexual violence, stalking, and psychological aggression. While the scope of IPV is not fully documented, nearly 40% of women in the US are victims of sexual violence in their lifetimes and 20% are victims of physical IPV. Other forms of IPV are likely particularly underreported. IPV has a substantial impact on a woman's physical and mental health...
May 24, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28551393/content-specificity-of-attentional-bias-to-threat-in-post-traumatic-stress-disorder
#4
A Zinchenko, M M Al-Amin, M M Alam, W Mahmud, N Kabir, H M Reza, T H J Burne
BACKGROUND: Attentional bias to affective information and reduced cognitive control may maintain the symptoms of post-traumatic stress disorder (PTSD) and impair cognitive functioning. However, the role of content specificity of affective stimuli (e.g., trauma-related, emotional trauma-unrelated) in the observed attentional bias and cognitive control is less clear, as this has not been tested simultaneously before. Therefore, we examined the content specificity of attentional bias to threat in PTSD...
May 18, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28549330/impact-of-post-traumatic-stress-disorder-on-oral-health
#5
Ana Cristina de Oliveira Solis, Álvaro Cabral Araújo, Felipe Corchs, Marcio Bernik, Érica Panzani Duran, Cláudio Silva, Francisco Lotufo-Neto
BACKGROUND: The stress experienced as an intense and traumatic event can increase the odds of orofacial pain, affect the biomechanics of masticatory system and compromise the periodontal health. This study was conducted to investigate the impact of post-traumatic stress disorder (PTSD) on oral health. METHODS: A case-control study with a convenience sample was designed. Probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing, and plaque were recorded at 6 sites per tooth...
May 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28549317/frontal-and-subcortical-grey-matter-reductions-in-ptsd
#6
Daniel C M O'Doherty, Ashleigh Tickell, Will Ryder, Charles Chan, Daniel F Hermens, Maxwell R Bennett, Jim Lagopoulos
Post-traumatic stress disorder (PTSD) is characterised by a range of debilitating psychological, physical and cognitive symptoms. PTSD has been associated with grey matter atrophy in limbic and frontal cortical brain regions. However, previous studies have reported heterogeneous findings, with grey matter changes observed beyond limbic/frontal areas. Seventy-five adults were recruited from the community, 25 diagnosed with PTSD along with 25 healthy and 25 trauma exposed age and gender matched controls. Participants underwent clinical assessment and magnetic resonance imaging...
May 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28545794/the-natural-history-of-sleep-disturbance-among-oef-oif-veterans-with-tbi-and-ptsd-and-the-role-of-proxy-variables-in-its-measurement
#7
Paul R King, Kerry T Donnelly, Gary Warner, Michael Wade, Wilfred R Pigeon
OBJECTIVE: Sleep disturbance crosscuts post-traumatic stress disorder (PTSD) and traumatic brain injury (TBI). Though previous cross-sectional findings demonstrate a compounding effect of PTSD and TBI comorbidity, relatively little is known about the longitudinal trajectory of sleep-related complaints in veterans with TBI history and current PTSD symptoms. In this study, we explored patterns and predictors of sleep complaints in a sample of combat veterans with and without TBI and PTSD...
May 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28544554/concept-analysis-of-posttraumatic-stress-disorder
#8
Bikram Sekhon
PURPOSE: Mental health nursing is not the same as psychiatry, so it is important for nurses to have an understanding of the defining attributes, antecedents, consequences, model cases, and empirical referents of post-traumatic stress disorder (PTSD). METHOD: Walker and Avant's (2005) method is used to guide this concept analysis of PTSD. FINDINGS: Four attributes arise from this concept analysis, which are addressed through both the DSM-IV and DSM-5 (American Psychiatric Association, /): triggering event or events, re-experiencing, fear, and helplessness...
May 23, 2017: International Journal of Nursing Knowledge
https://www.readbyqxmd.com/read/28543929/prevalence-and-impact-of-childhood-adversities-and-post-traumatic-stress-disorder-in-women-with-fibromyalgia-and%C3%A2-chronic-widespread-pain
#9
E Coppens, P Van Wambeke, B Morlion, N Weltens, H Giao Ly, J Tack, P Luyten, L Van Oudenhove
OBJECTIVE: This study investigates the prevalence of different types of childhood adversities (CA) and posttraumatic stress disorder (PTSD) in female patients with Fibromyalgia or Chronic Widespread Pain (FM/CWP) compared to patients with Functional Dyspepsia (FD) and achalasia. In FM/CWP, we also investigated the association between CA and PTSD on the one hand and pain severity on the other. METHODS: Patient samples consisted of 154 female FM/CWP, 83 female FD and 53 female achalasia patients consecutively recruited from a tertiary care hospital...
May 24, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28543322/why-did-adolescents-have-sleep-problems-after-earthquakes-understanding-the-role-of-traumatic-exposure-fear-and-ptsd
#10
Xiao Zhou, Xinchun Wu, Qiuyan Chen, Rui Zhen
To examine the relationships between trauma exposure, fear, post-traumatic stress disorder, and sleep problems in adolescents, 746 adolescent survivors of the 2008 Wenchuan earthquake in China were assessed at 1 year (T1) and 1.5 years (T2) after the earthquake using a trauma exposure questionnaire, a fear questionnaire, a child posttraumatic stress disorder symptom scale, and a subscale on child sleep problems. The results showed that T1 trauma exposure were not directly associated with sleep problems at T1 and T2, but played a positive role in sleep problems at both T1 and T2 indirectly through T1 posttraumatic stress disorder and T1 fear...
June 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/28539417/exposure-to-stressors-facilitates-long-term-synaptic-potentiation-in-the-lateral-habenula
#11
Hoyong Park, Jeehae Rhee, Kwanghoon Park, Jung-Soo Han, Roberto Malinow, ChiHye Chung
The lateral habenula (LHb) is a small part of the epithalamus that projects to monoamine centers in the brain. Previously, neurotransmission onto the LHb was shown to be abnormally potentiated in animal models of depression. However, synaptic plasticity in this brain area and the effect of stressor exposure on synaptic plasticity of the LHb have not been investigated. Thus, we explored whether the LHb undergoes dynamic changes in synaptic efficacy or not. First, we observed that a moderate long-term potentiation (LTP) occurs in a fraction of LHb neurons obtained from naïve Sprague Dawley rats...
May 24, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28535839/separation-from-parents-during-childhood-trauma-predicts-adult-attachment-security-and-post-traumatic-stress-disorder
#12
R A Bryant, M Creamer, M O'Donnell, D Forbes, K L Felmingham, D Silove, G Malhi, M van Hoof, A C McFarlane, A Nickerson
BACKGROUND: Prolonged separation from parental support is a risk factor for psychopathology. This study assessed the impact of brief separation from parents during childhood trauma on adult attachment tendencies and post-traumatic stress. METHOD: Children (n = 806) exposed to a major Australian bushfire disaster in 1983 and matched controls (n = 725) were assessed in the aftermath of the fires (mean age 7-8 years) via parent reports of trauma exposure and separation from parents during the fires...
May 24, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28534873/molecular-indicators-of-stress-induced-neuroinflammation-in-a-mouse-model-simulating-features-of-post-traumatic-stress-disorder
#13
S Muhie, A Gautam, N Chakraborty, A Hoke, J Meyerhoff, R Hammamieh, M Jett
A social-stress mouse model was used to simulate features of post-traumatic stress disorder (PTSD). The model involved exposure of an intruder (male C57BL/6) mouse to a resident aggressor (male SJL) mouse for 5 or 10 consecutive days. Transcriptome changes in brain regions (hippocampus, amygdala, medial prefrontal cortex and hemibrain), blood and spleen as well as epigenome changes in the hemibrain were assayed after 1- and 10-day intervals following the 5-day trauma or after 1- and 42-day intervals following the 10-day trauma...
May 23, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28532449/the-factor-structures-and-correlates-of-ptsd-in-post-conflict-timor-leste-an-analysis-of-the-harvard-trauma-questionnaire
#14
Alvin Kuowei Tay, Mohammed Mohsin, Susan Rees, Zachary Steel, Natalino Tam, Zelia Soares, Jessica Baker, Derrick Silove
BACKGROUND: Post-traumatic stress disorder (PTSD) is the most widely assessed form of mental distress in cross-cultural studies conducted amongst populations exposed to mass conflict and displacement. Nevertheless, there have been longstanding concerns about the universality of PTSD as a diagnostic category when applied across cultures. One approach to examining this question is to assess whether the same factor structure can be identified in culturally diverse populations as has been described in populations of western societies...
May 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28532277/temporal-parameters-of-post-stress-prophylactic-glucose-treatment-in-rats
#15
M A Conoscenti, E E Hart, N J Smith, T R Minor
Acute trauma can lead to life-long changes in susceptibility to psychiatric disease, such as Post-Traumatic Stress Disorder (PTSD). Rats given free access to a concentrated glucose solution for 24 hours beginning immediately after trauma failed to show stress-related pathology in the learned helplessness model of PTSD and comorbid major depression. We assessed effective dosing and temporal constraints of the glucose intervention in three experiments. We exposed 120 male Sprague-Dawley rats to 100, 1 mA, 3-15s, inescapable and unpredictable electric tail shocks (over a 110 minute period) or simple restraint in the learned helplessness procedure...
May 22, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28530344/-suppression-of-a-non-trauma-related-threatening-thought-as-an-avoidance-strategy-in-post-traumatic-stress-disorder-patients
#16
Lilach Abramsky-Arazi, Zeev Kaplan, Hagit Cohen
AIMS: Our goal was to examine how suppression of nontrauma- related thoughts differs between PTSD patients and patients with non-PTSD anxiety disorder compared to a group of matched controls. BACKGROUND: Intrusive recollections of aspects of the traumatic event and its sequelae are at the core of the post-traumatic stress disorder (PTSD). People who have suffered a traumatic event may implement some form of avoidance coping strategies in order to deal with the unwanted memories that accompany them...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28530342/-behavioral-physiological-and-morphological-characteristics-associated-with-post-traumatic-response-to-continuous-exposure-versus-alternate-exposure-in-an-animal-model-of-post-traumatic-stress-disorder
#17
Ishay Ostfeld, Zeev Kaplan, Hagit Cohen
AIMS: The aim of this study was to approximate these conditions in an animal model of post-traumatic stress disorder (PTSD). More specifically, the neurobiological basis of these conditions, focusing on stress-related behavioral changes, HPA-axis and morphological were evaluated. The intention was to employ this well-validated, reproducible and reliable model for PTSD, to elicit data which will provide some guidance in the planning of a prospective study involving military personal. BACKGROUND: Combat personnel are exposed to significant stress and hardship, both physical and emotional, during their service and especially during active combat...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28530340/-can-post-traumatic-stress-disorder-be-prevented-with-glucocorticoids
#18
REVIEW
Hagit Cohen, Zeev Kaplan, Joseph Zohar
Glucocorticoids (GCs) play a major role in orchestrating the complex physiological and behavioral reactions essential for the maintenance of homeostasis. These compounds enable the organism to prepare for, respond to and cope with the acute demands of physical and emotional stressors. The appropriate GC release, commensurate with stressor severity, enables the body to properly contain stress responses so as to promote recovery by rapidly restoring homeostasis. Indeed, inadequate GC release following stress not only delays recovery by disrupting biological homeostasis in the short run but can also interfere with the processing or interpretation of stressful information that results in long-term disruptions in memory integration...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28530334/-from-theory-to-practice-implementing-the-bio-psycho-social-model-in-clinical-and-research-activities-in-the-beer-sheva-mental-health-center
#19
Hagit Cohen, Doron Todder
The Beer Sheva Mental Health Center is the second largest mental health hospital in Israel and provides acute and chronic in-patient services for the entire population of the Southern District of Israel, from Ashdod to Eilat (about 1.2 million people) from adolescence to the elderly. The outpatient services include a variety of regional specialty services such as bipolar, eating disorders, anxiety, neuromodulation, gender-oriented, attention deficit hyperactivity disorder, sleep, dual diagnosis, geronto-psychiatry and post-traumatic stress disorder clinics and various rehabilitation day-care services...
December 2016: Harefuah
https://www.readbyqxmd.com/read/28528244/heart-rate-variability-of-chronic-posttraumatic-stress-disorder-in-the-korean-veterans
#20
Joo Eon Park, Ji Yeon Lee, Suk-Hoon Kang, Jin Hee Choi, Tae Yong Kim, Hyung Seok So, In-Young Yoon
Patients with post-traumatic stress disorder (PTSD) have lower heart rate variability (HRV) than the general population, but findings in this area have been inconsistent. This study was conducted to investigate the characteristics of HRV in patients with PTSD and to evaluate associations between PTSD symptoms and HRV indices. Sixty-eight patients with PTSD and 73 controls without PTSD were evaluated. HRV was measured in all subjects after they completed self-reported questionnaires. Patients with PTSD had significantly more depressed moods, anxiety, and poorer sleep quality than individuals in the non-PTSD group...
May 9, 2017: Psychiatry Research
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