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https://www.readbyqxmd.com/read/28734257/comparison-of-femoropopliteal-artery-stents-under-axial-and-radial-compression-axial-tension-bending-and-torsion-deformations
#1
Kaspars Maleckis, Paul Deegan, William Poulson, Cole Sievers, Anastasia Desyatova, Jason MacTaggart, Alexey Kamenskiy
High failure rates of Peripheral Arterial Disease (PAD) stenting appear to be associated with the inability of certain stent designs to accommodate severe biomechanical environment of the femoropopliteal artery (FPA) that bends, twists, and axially compresses during limb flexion. Twelve Nitinol stents (Absolute Pro, Supera, Lifestent, Innova, Zilver, Smart Control, Smart Flex, EverFlex, Viabahn, Tigris, Misago, and Complete SE) were quasi-statically tested under bench-top axial and radial compression, axial tension, bending, and torsional deformations...
July 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28729250/stellarex-drug-coated-balloon-for-treatment-of-femoropopliteal-disease-12-month-outcomes-from-the-randomized-illumenate-pivotal-and-pharmacokinetic-studies
#2
Prakash Krishnan, Peter Faries, Khusrow Niazi, Ash Jain, Ravish Sachar, William B Bachinsky, Joseph A Cardenas, Martin Werner, Marianne Brodmann, J A Mustapha, Carlos I Mena-Hurtado, Michael R Jaff, Andrew H Holden, Sean P Lyden
Background -Drug-coated balloons (DCB) are a predominant revascularization therapy for symptomatic femoropopliteal artery disease. Due to differences in excipients, paclitaxel dose and coating morphologies, varying clinical outcomes have been observed with different DCBs. We report the results of two studies investigating the pharmacokinetic (PK) and clinical outcomes of a new DCB to treat femoropopliteal disease. Methods -In the ILLUMENATE Pivotal Study, 300 symptomatic patients (Rutherford class 2-4), were randomized to DCB (N=200) or standard angioplasty (PTA) (N=100)...
July 20, 2017: Circulation
https://www.readbyqxmd.com/read/28722377/-sweet-s-syndrome-a-diagnosis-to-keep-in-mind
#3
Caroline Lang, Sandrine Quenan
Sweet's syndrome is a rare neutrophilic dermatosis. Typically, patients present with a sudden onset of tender erythematous skin lesions (papules, nodules, and plaques), of asymetrical distribution, located preferentially on the superior limbs, face and neck, associated whith high fever and neutrophilia. Histologicaly, there is a diffuse infiltrate of neutrophils located in the dermis. Most of the time idiopathic, it may be associated with a respiratory or gastro-intestinal infection, with inflammatory bowel disease, pregnancy and vaccination...
March 29, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28718171/younger-patients-and-men-achieve-higher-outcome-scores-than-older-patients-and-women-after-anterior-cruciate-ligament-reconstruction
#4
Kate E Webster, Julian A Feller
BACKGROUND: There is some evidence that functional performance and validated outcome scores differ according to the gender, age, and sport participation status of a patient after anterior cruciate ligament (ACL) reconstruction. However, the impact of these three factors, and interaction among them, has not been studied across a large relatively homogeneous group of patients to better elucidate their impact. QUESTIONS/PURPOSES: We reviewed a large cohort of patients who had undergone ACL reconstruction to determine if ROM, knee laxity, objective performance measures, and validated outcome scores differed according to (1) gender; (2) age; and (3) sport participation status...
July 17, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28715806/real-time-volume-contrast-imaging-in-the-a-plane-with-a-four-dimensional-electronic-probe-facilitates-the-evaluation-of-fetal-extremities-in-midtrimester-sonograms
#5
Federica Bellussi, Giuliana Simonazzi, Ginevra Salsi, Francesca Guasina, Gianluigi Pilu
OBJECTIVE: To evaluate the efficiency of real-time volume contrast imaging in the A plane (VCI-A) of fetal extremities, compared with conventional two-dimensional ultrasound (2D). METHODS: This was a randomized controlled trial of 100 patients undergoing midtrimester sonography. The fetal limbs were imaged with either 2D or VCI-A with a four-dimensional (4D) electronic probe. Time required for the examination, number of images stored, and quality of the documentation were compared...
July 18, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28711623/prioritized-cervical-or-lumbar-surgery-for-coexisting-cervical-and-lumbar-stenosis-prognostic-analysis-of-222-case
#6
Haoxi Li, Zhaoxiong Chen, Xinhua Li, Tao Liu, Bin Shen, Yufeng Huang, Desheng Wu
BACKGROUND CONTEXT: Single-stage surgery is usually applied to improving the symptoms of coexisting cervical and lumbar stenosis. In most cases, patients' willingness, surgery affordability, surgical trauma, surgical complications and patients' tolerance to surgery all limit the application of single-stage surgery. For patients who cannot receive single-stage surgery, we hope that we can find out by weighing up merits and flaws of the two surgical sites in order to make decision of prioritize one of the two surgery, so as to bring more benefits to the patients...
July 12, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28709915/sex-differences-in-somatic-and-sensory-motor-development-after-neonatal-anoxia-in-wistar-rats
#7
Amrita Jha Kumar, Silvia Honda Takada, Lívia Clemente Motta-Teixeira, Vitor Yonamine Lee, Gilberto Fernando Xavier, Maria Inês Nogueira
Currently, one of the important causes of brain injury in new-borns is the neonatal anoxia which impacts the perinatology services worldwide. Animal models of anoxia have been used to assess its effects at cellular and behavioural levels in all ages, but few studies focus on sex differences. This study aimed to investigate some physical parameters of development, sensorimotor alterations, early neurological reflexes as well as the density of cells in motor and sensorimotor cerebral cortex of adolescent rats submitted to neonatal anoxia...
July 12, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28704294/early-detection-of-neonatal-hypoxic-ischemic-white-matter-injury-an-mr-diffusion-tensor-imaging-study
#8
Youngseob Seo, Geun-Tae Kim, Jin Wook Choi
The purpose of this study was to compare diffusion tensor metrics in normal age-matched neonates with survivors of hypoxic-ischemic encephalopathy (HIE) and extracorporeal membrane oxygenation (ECMO). Thirty-five normal, 27 HIE, and 13 ECMO infants underwent MRI at 3 T. Neurodevelopmental assessments were performed. Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) of the inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, anterior commissure, genu corpus callosum and splenium of the corpus callosum, anterior and posterior limb of the internal capsule, superior longitudinal fasciculus, and the centrum semiovale were analyzed with tract-based spatial statistics modified for use in neonates...
July 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/28700180/-superior-cava-vein-stenosis-in-a-hemodialysis-patient-with-long-term-central-venous-catheter-and-vascular-graft-a-case-report
#9
Carlo Jovane, Piera Farfaglia, Anna Maria Ierardi, Laura Rimoldi, Elisabetta Sogni, Carmela Figliola, Daniela Pogliani, Matteo Tozzi, Elena Caramella, Pasquale Esposito, Alessandro Castiglioni
Recently, the use of central venous catheters (CVC) as a vascular access in patients undergoing hemodialysis is significantly increased, mainly because of the aging of this population and the presence of several comorbidities. However, the implantation and the long stay of CVC are associated with many complications. Among them, central venous stenosis represents one of the most common problems that, if not properly diagnosed, could lead to vascular thrombosis and consequent vascular access malfunction. Here, we report a case of a 38-year-old patient, who underwent hemodialysis firstly by a CVC long-term into right jugular vein and then by a prosthetic fistula in the ipsilateral limb...
June 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28678699/turn-intent-detection-for-control-of-a-lower-limb-prosthesis
#10
Corey Pew, Glenn Klute
OBJECTIVE: An adaptable lower limb prosthesis with variable stiffness in the transverse plane requires a control method to effect changes in real time during amputee turning. This study aimed to identify classification algorithms that can accurately predict turning using inertial measurement unit (IMU) signals from the shank with adequate time to enact a change in stiffness during the swing phase of gait when the prosthesis is unloaded. METHODS: To identify if a turning step is imminent, classification models were developed around activities of daily living including 90? spin turns, 90? step turns, 180? turns, and straight walking using simulated IMU data from the prosthesis shank...
June 28, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28678059/peripheral-interventions-for-painful-stump-neuromas-of-the-lower-limb-a-systematic-review
#11
Stephanie Alexandra Poyntz, Milind Dalal, Nicholas Hacking, Stephen Fowler
OBJECTIVES: Painful stump neuromas in lower limb amputees are a significant burden on a person's quality of life due to interference with wearing prostheses and therefore the ability to walk. Treating painful stump neuromas is a challenge perhaps reflected by the lack of clinical guidelines both in the United Kingdom and internationally. METHODS: A systematic review was conducted to evaluate the efficacy of all treatments tried in the management of symptomatic neuromas in the lower limb amputation stump in order to establish whether one treatment is superior...
July 3, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28675473/localization-of-orofacial-representation-in-the-corona-radiata-internal-capsule-and-cerebral-peduncle-in-macaca-mulatta
#12
R J Morecraft, A Binneboese, K S Stilwell-Morecraft, J Ge
Subcortical white matter injury is often accompanied by orofacial motor dysfunction, but little is known about the structural substrates accounting for these common neurological deficits. We studied the trajectory of the corticobulbar projection from the orofacial region of the primary (M1), ventrolateral (LPMCv), supplementary (M2), rostral cingulate (M3) and caudal cingulate (M4) motor regions through the corona radiata (CR), internal capsule (IC) and crus cerebri of the cerebral peduncle (ccCP). In the CR each pathway was segregated...
July 4, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28673669/cerebral-venous-sinus-thrombosis-complicated-with-acute-development-of-dural-arteriovenous-fistula-a-case-report
#13
Ji-Gang Chen, Zhen-Xing Li, Dan-Feng Zhang, Jun-Yu Wang, Li-Jun Hou
Development of dural arteriovenous fistula (dAVF) after cerebral venous sinus thrombosis (CVST) was very uncommon and for all these reported cases, the dAVF was a chronic complication. We present a case of acute development of dAVF after CVST. A 40-year-old female was admitted into our department with 2day's headache and vomiting for 9h. Head computed tomography (CT) scan showed only scattered minor hematomas over the right frontal lobe. Blood test indicated an elevated D-dimer. The patient experienced transient paralysis (Todd's paralysis) after intermittent focal epilepsy from day 3, which progressed into sustained epilepsy on day 6...
June 30, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28669300/contralateral-c-7-transfer-is-direct-repair-really-superior-to-grafting
#14
Anil Bhatia, Piyush Doshi, Ashok Koul, Vitrag Shah, Justin M Brown, Mahmoud Salama
It is not uncommon for a severe traumatic brachial plexus injury to involve all 5 roots, resulting in a flail upper limb. In such cases, surgical reconstruction is often palliative, providing only rudimentary function. Nerve transfers are the mainstay of reconstructive strategies due to the predominance of root avulsions. Consistent results are obtained only for restoration of shoulder stability and elbow flexion, whereas restoring useful hand function remains a challenge. The transfer of the contralateral C-7 (cC-7) is commonly used in an attempt to restore basic hand function, but results are notoriously unreliable and inconsistent...
July 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28662867/thoracic-outlet-syndrome-after-the-nuss-procedure-for-pectus-excavatum-is-it-a-rare-complication
#15
Tomohisa Nagasao, Tadaaki Morotomi, Motone Kuriyama, Tetsukuni Kogure, Hirro Kudo, Yusuke Hamamoto, Motoki Tamai
OBJECTIVE: The present study aims to elucidate the frequency of thoracic outlet syndrome after the Nuss procedure for pectus excavatum and the conditions in which thoracic outlet syndrome is likely to develop. METHODS: A retrospective study including 85 pectus excavatum patients (58 males and 27 females) was conducted. Thoracic outlet syndrome was defined as a condition in which the patient has numbness, lassitude, or pain of the upper limbs at rest or during motion of the upper limbs...
June 3, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28658200/critical-ischemia-times-and-the-effect-of-novel-preservation-solutions-htk-n-and-tiprotec-on-tissues-of-a-vascularized-tissue-isograft
#16
Franka Messner, Theresa Hautz, Michael Jf Blumer, Mario Bitsche, Elisabeth J Pechriggl, Martin Hermann, Bettina Zelger, Bernhard Zelger, Dietmar Öfner, Stefan Schneeberger
BACKGROUND: We herein investigate critical ischemia times and the effect of novel preservation solutions HTK-N and TiProtec on the individual tissues of a rat limb isograft. METHODS: Orthotopic hind-limb transplantations were performed in male Lewis rats following 2h, 6h or 10h of cold ischemia. Limbs were flushed and stored in either HTK-N, TiProtec, HTK or saline solution. Muscle, nerve, vessel, skin and bone samples were procured on day 10 for histology, immunohistochemistry, confocal and electron microscopy and RTqPCR analysis...
June 28, 2017: Transplantation
https://www.readbyqxmd.com/read/28654608/the-efficacy-of-perforator-flaps-in-the-treatment-of-chronic-osteomyelitis
#17
Joon Pio Jp Hong, Terence L H Goh, Dong Hoon Choi, Jung Jae Kim, Hyun Suk Suh
BACKGROUND: Treatment of chronic osteomyelitis involves aggressive débridement followed by soft-tissue coverage. The dictum of muscle coverage being superior has been challenged by successful reports of coverage with skin flaps. The objective of this article is to evaluate the efficacy of perforator flaps for reconstruction of chronic osteomyelitis defects. METHODS: A retrospective review of 120 patients with chronic osteomyelitis who underwent débridement and reconstruction using perforator flaps from April of 2000 to November of 2015 was conducted...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28648791/drug-eluting-stents-versus-control-therapy-in-the-infrapopliteal-disease-a-meta-analysis-of-eight-randomized-controlled-trials-and-two-cohort-studies
#18
REVIEW
Xiaochun Liu, Guofu Zheng, Song Wen
BACKGROUD: Drug-eluting stents (DES) have been proposed for the treatment of infrapopliteal arteries disease. However, the long-term clinical impact of DES treatment in the vascular territory still remains uncertain. METHODS AND RESULTS: Pubmed, Embase, Cochrane data, CNKI and Wanfang Data were searched until December 20, 2016 for eligible studies according to identical strategies. Additional data were manually retrieved. STATA ver. 12.0 software were used to Meta-analyze the efficacies of DES and control treatment (BMS or PTA) for infrapopliteal arteries disease...
June 23, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28648654/gianturco-z-stent-fixation-of-a-modified-iliac-limb-stent-graft-endoprosthesis-for-the-treatment-of-malignant-superior-vena-cava-syndrome
#19
Jeffrey Forris Beecham Chick, Matthew L Osher, Kyle J Cooper, Wael A Saad, David M Williams, Minhaj S Khaja
Superior vena cava (SVC) syndrome, characterized by facial and arm swelling, is most frequently caused by intrathoracic malignancies. Decompression may be achieved with endovenous stent placement. Polytetrafluoroethylene-covered stents have shown to have higher long-term cumulative patency rates compared with uncovered stents for the treatment of malignant SVC syndrome. Unfortunately, polytetrafluoroethylene-covered stents are not readily available worldwide. Moreover, the existing armamentarium, including balloon-expandable iCAST stents (maximum diameter 10 mm) and heparin-coated Viabahn stent-graft endoprostheses (maximum diameter 13 mm), are too small to adequately treat malignant obstruction of the SVC...
June 23, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28648324/drug-coated-balloon-angioplasty-for-the-management-of-recurring-infrapopliteal-disease-in-diabetic-patients-with-critical-limb-ischemia
#20
Luis M Palena, Larry J Diaz-Sandoval, Efren Gòmez Jabalera, Olga Peypoch Perez, Enrico Sultato, Cesare Brigato, Enrico Brocco, Marco Manzi
OBJECTIVE: To describe the 1-year outcomes of recurring infrapopliteal disease after endovascular revascularization with the Lutonix drug-coated balloons (LDCB) in diabetic patients with critical limb ischemia (CLI), and to benchmark our findings with previously published objective performance goals (OPG) addressing safety and efficacy of new catheter-based therapies for CLI. METHODS: The present study was a retrospective, single-center, and single-arm trial of symptomatic diabetic patients with CLI, who underwent LDCB-angioplasty for recurring infrapopliteal disease...
June 20, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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