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https://www.readbyqxmd.com/read/29148000/the-feasibility-and-safety-of-piccs-accessed-via-the-superficial-femoral-vein-in-patients-with-superior-vena-cava-syndrome
#1
Yonghui Wan, Yuxin Chu, Yanru Qiu, Qian Chen, Wei Zhou, Qibin Song
OBJECTIVE: To investigate the feasibility and safety of the peripherally inserted central catheters (PICCs) accessed via the superficial femoral vein in patients with superior vena cava syndrome (SVCS). METHODS: From October 2010 to December 2014, 221 cancer patients with SVCS in our center received real-time ultrasound-guidance of the superficial femoral vein inserted central catheters (FICCs) at the mid-thigh. PICC insertion via upper extremity veins had also been investigated in 2604 cancer patients without SVCS as control...
November 10, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/29143001/easily-fabricated-and-lightweight-ppy-pda-agnw-composites-for-excellent-electromagnetic-interference-shielding
#2
Yan Wang, Fu-Qiang Gu, Li-Juan Ni, Kun Liang, Kyle Marcus, Shu-Li Liu, Fan Yang, Jin-Ju Chen, Zhe-Sheng Feng
Conductive polymer composites (CPCs) containing nanoscale conductive fillers have been widely studied for their potential use in various applications. In this paper, polypyrrole (PPy)/polydopamine (PDA)/silver nanowire (AgNW) composites with high electromagnetic interference (EMI) shielding performance, good adhesion ability and light weight are successfully fabricated via a simple in situ polymerization method followed by a mixture process. Benefiting from the intrinsic adhesion properties of PDA, the adhesion ability and mechanical properties of the PPy/PDA/AgNW composites are significantly improved...
November 16, 2017: Nanoscale
https://www.readbyqxmd.com/read/29142090/virtual-reality-training-for-upper-extremity-in-subacute-stroke-virtues-a-multicenter-rct
#3
Iris Brunner, Jan Sture Skouen, Håkon Hofstad, Jörg Aßmus, Frank Becker, Anne-Marthe Sanders, Hanne Pallesen, Lola Qvist Kristensen, Marc Michielsen, Liselot Thijs, Geert Verheyden
OBJECTIVE: To compare the effectiveness of upper extremity virtual reality rehabilitation training (VR) to time-matched conventional training (CT) in the subacute phase after stroke. METHODS: In this randomized, controlled, single-blind phase III multicenter trial, 120 participants with upper extremity motor impairment within 12 weeks after stroke were consecutively included at 5 rehabilitation institutions. Participants were randomized to either VR or CT as an adjunct to standard rehabilitation and stratified according to mild to moderate or severe hand paresis, defined as ≥20 degrees wrist and 10 degrees finger extension or less, respectively...
November 15, 2017: Neurology
https://www.readbyqxmd.com/read/29140077/superior-robust-ultra-thin-single-crystalline-silicon-carbide-membrane-as-a-versatile-platform-for-biological-applications
#4
Tuan-Khoa Nguyen, Hoang-Phuong Phan, Harshad Kamble, Raja Vadivelu, Toan Khac Dinh, Alan Iacopi, Glenn Walker, Leonie Hold, Nam-Trung Nguyen, Dzung Viet Dao
Micro-machined membranes are promising platforms for cell culture thanks to their miniaturization and integration capabilities. Possessing chemical inertness, bio compatibility and integration, silicon carbide (SiC) membranes have attracted great interest towards biological applications. In this paper, we present the batch fabrication, mechanical characterizations, and cell culture demonstration of robust ultra-thin epitaxial deposited SiC membranes. The as-fabricated ultra-thin SiC membranes, with an ultra-high aspect ratio (length/thickness) of up to 20,000, possess high a fracture strength up to 2...
November 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29137187/clinical-usefulness-of-the-platelet-to-lymphocyte-ratio-in-patients-with-angiosarcoma-of-the-face-and-scalp
#5
Gen Suzuki, Hideya Yamazaki, Norihiro Aibe, Koji Masui, Naomi Sasaki, Daisuke Shimizu, Takuya Kimoto, Jun Asai, Makoto Wada, Satoshi Komori, Norito Katoh, Kei Yamada
Angiosarcoma of the face and scalp (ASFS) is an extremely aggressive tumor that frequently metastasizes, often leading to death. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) are inflammatory markers that predict outcome of various cancers. We aimed to examine the relationship between pretreatment inflammatory markers and ASFS outcome. We included 17 patients with ASFS and a control group of 56 age- and gender-matched healthy individuals...
November 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29134990/dft-coupled-with-negf-study-of-ultra-sensitive-hcn-and-hnc-gases-detection-and-distinct-i-v-response-based-on-phosphorene
#6
Jiu Pang, Qun Yang, Xiaosong Ma, Liming Wang, Chunjian Tan, Daxi Xiong, Huaiyu Ye, Xianping Chen
The sensing performances of pristine and X-doped phosphorene substrates (X = Al, Si, and S atoms) toward the adsorption of the toxic gases HCN and HNC were systematically investigated by first-principles simulations. The numerical results show that the pristine phosphorene is sensitive to HCN and HNC molecules with moderate adsorption energy, excellent charge transfer, high sensitivity and selectivity, implying its potential applications as excellent HCN and HNC sensors. In addition, the Al-doped phosphorene exhibits extremely high reactive activity toward HCN and HNC gases; thus, it has potential for use as a metal-free catalyst for activating or catalyzing HCN or HNC adsorbates...
November 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29133604/canagliflozin-for-primary-and-secondary-prevention-of-cardiovascular-events-results-from-the-canvas-program-canagliflozin-cardiovascular-assessment-study
#7
Kenneth W Mahaffey, Bruce Neal, Vlado Perkovic, Dick de Zeeuw, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Elisa Fabbrini, Tao Sun, Qiang Li, Mehul Desai, David R Matthews
BACKGROUND : Canagliflozin is a sodium glucose cotransporter 2 inhibitor that significantly reduces the composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with type 2 diabetes mellitus and elevated cardiovascular risk. The comparative effects among participants with and without a history of cardiovascular disease (secondary versus primary prevention) were prespecified for evaluation. METHODS : The CANVAS Program (Canagliflozin Cardiovascular Assessment Study) randomly assigned 10 142 participants with type 2 diabetes mellitus to canagliflozin or placebo...
November 13, 2017: Circulation
https://www.readbyqxmd.com/read/29131235/anatomical-variations-of-brachial-plexus-in-fetal-cadavers
#8
Alparslan Kirik, Senem Ertuğrul Mut, Mehmet Kadri Daneyemez, Halil İbrahim Seçer
AIM: The plexus brachialis is a complex structure with anatomical variations and connections with neighboring tissues. These variations may cause disparity in the motor and sensorial innervations of the upper extremity. The knowledge of anatomy and probable variations are important for performing surgical procedures in the neck, shoulder and axilla. This study was planned to demonstrate the anatomical variations of infantile brachial plexus. MATERIAL AND METHODS: A total of 20 plexus brachialis from 11 fetal cadavers were dissected and examined microscopically...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29125567/data-retention-characterization-of-gate-injected-gold-nanoparticle-non-volatile-memory-with-low-damage-cf%C3%A2-plasma-treated-blocking-oxide-layer
#9
Yu-Hua Liu, Chyuan-Haur Kao, Tsung-Chin Cheng, Chih-I Wu, Jer-Chyi Wang
Gold-nanoparticle (Au-NP) non-volatile memories (NVMs) with low-damage CF₄ plasma treatment on the blocking oxide (BO) layer have been investigated to present the gate injection of the holes. These holes, injected from the Al gate with the positive gate bias, were explained by the bandgap engineering of the gradually-fluorinated BO layer and the effective work function modulation of the Al gate. The Si-F complex in the BO layer was analyzed by X-ray photoelectron spectroscopy (XPS), while the depth of fluorine incorporation was verified using a secondary ion mass spectrometer (SIMS)...
November 10, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29123896/superior-mesenteric-artery-syndrome-leading-to-reversible-mucosal-gangrene
#10
Satomi Uemura, Kei Suzuki, Naoyuki Katayama, Hiroshi Imai
We describe a case in which gastrointestinal distention due to superior mesenteric artery syndrome (SMAS) developed into membranous gangrene, which in turn led to septic shock in a 60-year-old woman with cerebral palsy and cachexia. The association with SMAS and septic shock is considered extremely rare, it is important to consider this combination especially in cachectic patients with gastric distension accompanying refractory shock unknown etiology.
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29122235/-acute-stress-and-broken-heart-syndrome-a-case-report
#11
Juliana Vergel, Sebastián Tamayo-Orozco, Andrés Felipe Vallejo-Gómez, María Teresa Posada, Diana Restrepo
INTRODUCTION: Stress has been associated with an acute heart failure syndrome of important morbidity and mortality. METHODS: Case report and non-systematic review of the relevant literature. CASE PRESENTATION: A 65-year-old woman with a history of an untreated generalized anxiety disorder, whom after the violent death of her son presented with oppressive chest pain irradiated to neck and left superior extremity, lasting for more than 30minutes, initial clinical suspect suggests acute coronary syndrome...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29121540/computer-aided-diagnosis-of-diabetic-foot-using-infrared-thermography-a-review
#12
Muhammad Adam, Eddie Y K Ng, Jen Hong Tan, Marabelle L Heng, Jasper W K Tong, U Rajendra Acharya
Diabetes mellitus (DM) is a chronic metabolic disorder that requires regular medical care to prevent severe complications. The elevated blood glucose level affects the eyes, blood vessels, nerves, heart, and kidneys after the onset. The affected blood vessels (usually due to atherosclerosis) may lead to insufficient blood circulation particularly in the lower extremities and nerve damage (neuropathy), which can result in serious foot complications. Hence, an early detection and treatment can prevent foot complications such as ulcerations and amputations...
October 26, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29111688/durable-anti-superbug-polymers-covalent-bonding-of-ionic-liquid-onto-the-polymer-chains
#13
Jipeng Guan, Yanyuan Wang, Shilu Wu, Yongjin Li, Jingye Li
Here, we fabricated the ionic liquid (IL) grafted poly(vinylidene fluoride) (PVDF) (PVDF-g-IL) via electron-beam irradiation to fight common bacteria and multidrug-resistant "superbugs". Two types of ILs, 1-vinyl-3-butylimmidazolium chloride (IL (Cl)) and 1-vinyl-3-ethylimidazolium tetrafluoroborate (IL (BF4)), were used. It was found that the PVDF-g-IL exhibited superior antibacterial performance, with almost the same mechanical and thermal performance as unmodified PVDF. Nonwovens and films made from PVDF-g-IL materials exhibited broad-spectrum antimicrobial activity against common bacteria and "superbugs" with the strong electrostatic interactions between ILs and microbial cell membranes...
November 16, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/29108411/hollow-n-doped-carbon-spheres-with-isolated-cobalt-single-atomic-sites-superior-electrocatalysts-for-oxygen-reduction
#14
Han Yunhu, Yang-Gang Wang, Wenxing Chen, Ruirui Xu, Li Rong Zheng, Jian Zhang, Jun Luo, Rong-An Shen, Youqi Zhu, Weng-Chon Cheong, Chen Chen, Qing Peng, Dingsheng Wang, Yadong Li
To search a low-cost, ultrastable and highly efficient non-precious metal catalyst substituting Pt for oxygen reduction is extremely urgent, especially in acidic media. Herein, we devel-oped a template-assistant-pyrolysis (TAP) method to obtain a unique Co catalyst with isolated single atomic sites anchored on hollow N-doped carbon sphere (ISAS-Co/HNCS). Both the single sites and the hollow substrate endow the catalyst with excellent ORR performance. The half-wave potential in acidic media approaches that of commercial Pt/C...
November 6, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29106053/population-pharmacokinetics-of-fosdagrocorat-pf-04171327-a-dissociated-glucocorticoid-receptor-agonist-in-patients-with-rheumatoid-arthritis
#15
Barry Weatherley, Lynn McFadyen, Brinda Tammara
Dissociated agonists of the glucocorticoid receptor (DAGRs) show similar antiinflammatory effects but improved tolerability compared with standard glucocorticoid receptor (GR) agonists. The prodrug fosdagrocorat (PF-04171327), with active DAGR metabolite PF-00251802 (Metabolite-1), is postulated to show superior efficacy over placebo and prednisone in patients with moderate to severe rheumatoid arthritis (RA). We investigated the population pharmacokinetics of active Metabolite-1 and its active metabolite PF-04015475 (Metabolite-2) in patients with moderate to severe RA enrolled in a 12-week, phase II, randomized, double-blind study (NCT01393639)...
November 4, 2017: Clinical and Translational Science
https://www.readbyqxmd.com/read/29099414/transversus-abdominis-plane-catheters-for-analgesia-following-abdominal-surgery-in-adults
#16
Brenton J Sanderson, Matthew A Doane
Transversus abdominis plane (TAP) catheters are increasingly being used as an opioid-sparing analgesic technique following abdominal surgery. The aim of this systematic review is to evaluate the efficacy and safety of TAP catheters for postoperative analgesia following abdominal surgery in adults. The authors searched electronic databases and relevant reference lists for randomized controlled trials published between inception and January 2017. Twelve randomized controlled trials were identified, comprising 661 participants, with several trials showing either an equivalence or superiority in analgesia compared with the alternative modality...
November 2, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29097650/leiomyosarcoma-of-the-inferior-vena-cava-in-an-hiv-positive-adult-patient-a-case-report-and-review-of-the-literature
#17
Jing Xu, Arash Velayati, Barbara J Berger, Ming Liu, Naga K Sucharita Cheedella, Vladimir Gotlieb
BACKGROUND Leiomyosarcoma is the most common primary malignancy of the inferior vena cava (IVC), and represents approximately 10% of primary retroperitoneal sarcomas. Leiomyosarcoma presents with non-specific symptoms, including abdominal pain or back pain. There is an increased incidence in immunosuppressed individuals. CASE REPORT An unusual presentation of IVC leiomyosarcoma is reported in a 46-year-old female patient infected with human immunodeficiency virus (HIV) who was on highly active antiretroviral therapy (HAART) and who had a normal CD4 count of 934, who presented with back pain...
November 3, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29090573/label-free-and-nondestructive-separation-technique-for-isolation-of-targeted-dna-from-dna-protein-mixture-using-magnetic-au-fe3o4-nanoprobes
#18
Ankan Dutta Chowdhury, Nidhi Agnihotri, Ruey-An Doong, Amitabha De
The interest in DNA-protein-based diagnostics has recently been growing enormously, which makes the separation process of DNA or protein from a cell extract extremely important. Unlike the traditional separation process, a novel approach is in demand which can nondestructively isolate the target biomolecules without sacrificing the other components in the mixture. In this study, we have demonstrated a new and simple separation technique by using well-established bifunctional Au-Fe3O4 nanocomposites as the separation nanoprobes to efficiently isolate the specifically targeted nanomolar concentrated DNA over 70% from its associate DNA-protein mixture in the presence of a magnetic field...
November 10, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29080821/poly-carboxybetaine-methacrylate-functionalized-magnetic-composite-particles-a-biofriendly-support-for-lipase-immobilization
#19
Haishan Qi, Yan Du, Guannan Hu, Lei Zhang
In this work, poly(carboxybetaine methacrylate) as an extremely hydrophilic polymer was modified on superparamagnetic Fe3O4 nanoparticles (pCB-Fe3O4), which were employed to immobilize porcine pancreatic lipase. The properties of immobilized lipase were investigated in comparison with the free enzyme counterpart. Enzymatic stability, reusability, and activity of the immobilized lipase were found significantly superior to that of the free lipase. In particular, at an elevated temperature of 60°C, the immobilized lipase retained 50% of its initial activity after 150min, while the free enzyme displayed only one-third activity of the immobilized enzyme...
October 26, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29077809/linking-metabolic-network-features-to-phenotypes-using-sparse-group-lasso
#20
Satya Swarup Samal, Ovidiu Radulescu, Andreas Weber, Holger Fröhlich
Motivation: Integration of metabolic networks with '-omics' data has been a subject of recent research in order to better understand the behaviour of such networks with respect to differences between biological and clinical phenotypes. Under the conditions of steady state of the reaction network and the non-negativity of fluxes, metabolic networks can be algebraically decomposed into a set of sub-pathways often referred to as extreme currents (ECs). Our objective is to find the statistical association of such sub-pathways with given clinical outcomes, resulting in a particular instance of a self-contained gene set analysis method...
November 1, 2017: Bioinformatics
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