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Superior extremity

Chun-De Liao, Jau-Yih Tsauo, Hung-Chou Chen, Tsan-Hon Liou
OBJECTIVE: Extracorporeal shock wave therapy (ESWT), including radial shock wave (RaSW) and focused shock wave (FoSW) types, is widely used for managing tendinopathies. The difference in efficacy between the 2 shock wave characteristics with different dosage levels remains controversial, and the purpose of this meta-analysis was to examine it for patients with lower extremity (LE) tendinopathy. DESIGN: A comprehensive search of online databases and search engines was performed...
March 19, 2018: American Journal of Physical Medicine & Rehabilitation
Chiara DE Biase, Antonios Mastrokostopoulos, Raphael Philippart, Laurent Bonfils, Pierre Berthoumieu, Nicolas Dumonteil
Transcatheter aortic valve implantation (TAVI) is a recognized therapy for patients with symptomatic severe aortic stenosis (AS). TAVI is superior compared to medical therapy as for mortality in extreme-risk patients, is non-inferior or superior to surgery in high- risk patients and non-inferior to surgery in intermediate-risk patients. However, several limitations affect outcomes after TAVI. Adverse events related to this procedure, like vascular complications, need forpacemaker implantation, paravalvular regurgitation, can be factors limiting TAVI treatment in younger patients at lower risk, as well as uncertainties regarding valve durability...
March 19, 2018: Journal of Cardiovascular Surgery
Haofeng Gao, Chanjuan Li, Ramesh Bandikari, Ziduo Liu, Nan Hu, Qiang Yong
BACKGROUND: In industries lipolytic reactions occur in insensitive conditions such as high temperature thus novel stout esterases with unique properties are attracts to the industrial application. Protein engineering is the tool to obtain desirable characters of enzymes. A novel esterase gene was isolated from South China Sea and subjected to a random mutagenesis and site directed mutagenesis for higher activity and thermo-stability compared to wild type. RESULTS: A novel esterase showed the highest hydrolytic activity against p-nitrophenyl acetate (pNPA, C2) and the optimal activity at 40 °C and pH 8...
March 19, 2018: Microbial Cell Factories
Miltos K Lazarides, Christos Argyriou, Andreas Koutsoumpelis, Efstratios I Georgakarakos, George S Georgiadis
Thigh arteriovenous grafts are required in a number of patients with exhausted upper extremity veins and comprise 1%-5% of the total access procedures performed. Alternative autogenous lower extremity options are the rarely used sapheno-tibial arteriovenous fistulae, the saphenous vein transpositions, and the femoral vein transpositions. The latter have proven to be the most durable lower limb access procedures, with low infection rates and their primary patency rates ranged from 74% up to 87% at 2 years...
March 1, 2018: Journal of Vascular Access
Chunyan Chen, Ni Sun, Dongsheng Li, Sihua Long, Xiaoyu Tang, Guoqing Xiao, Linyuan Wang
Kitchen waste oil (KWO) from catering industries or households was used as a low-cost carbon source for producing biosurfactants by self-isolated Pseudomonas aeruginosa. Fermentation performance with KWO was superior to those with four other carbon sources, with higher optical density (OD600 ) of 2.33 and lower interfacial tension of 0.57 mN/m. Culture conditions for biosurfactant production were optimized, with optimal pH of 8.0 and nitrogen source concentration of 2.0 g/L, respectively. The results of infrared spectroscopy and liquid chromatography-mass spectrometry (LC-MS) showed that the biosurfactant was a mixture of six rhamnolipid congeners, among which Rha-Rha-C10 -C10 and Rha-C10 -C10 were the main components, with mass fraction of approximately 34...
March 16, 2018: Environmental Science and Pollution Research International
Keiji Uchida, Norihisa Karube, Keiichiro Kasama, Tomokazu Minami, Shota Yasuda, Motohiko Goda, Shinichi Suzuki, Kiyotaka Imoto, Munetaka Masuda
OBJECTIVE: The control of malperfusion is the key to improving the outcomes of surgery for type A acute aortic dissection. We revised our treatment strategy to reperfuse each ischemic organ before central repair. METHODS: Our current early reperfusion strategy consists of percutaneous coronary artery intervention for coronary malperfusion, direct surgical fenestration for carotid artery occlusion, active perfusion of the superior mesenteric artery for visceral malperfusion, and external shunting from the brachial artery to the femoral artery for lower limb ischemia...
February 13, 2018: Journal of Thoracic and Cardiovascular Surgery
Malgorzata A Gazda, Pedro Andrade, Sandra Afonso, Jolita Dilyte, John P Archer, Ricardo J Lopes, Rui Faria, Miguel Carneiro
Racing pigeons have been selectively bred to find their way home quickly over what are often extremely long distances. This breed is of substantial commercial value and is also an excellent avian model to gain empirical insights into the evolution of traits associated with flying performance and spatial orientation. Here, we investigate the molecular basis of the superior athletic and navigational capabilities of racing pigeons using whole-genome and RNA sequencing data. We inferred multiple signatures of positive selection distributed across the genome of racing pigeons...
March 13, 2018: Molecular Biology and Evolution
Tingting Liu, Shuo Wang, Qiuju Zhang, Liang Chen, Weihua Hu, Chang Ming Li
Ultrasmall ruthenium phosphide nanoparticles grown on reduced graphene oxide nanosheets (Ru2P/RGO-20) are reported as a highly efficient hydrogen evolution reaction (HER) catalyst. It achieves a current density of -10 mA cm-2 at extremely low overpotentials of -22 and -13 mV under acidic and alkaline conditions, respectively, superior to those of commercial Pt/C.
March 16, 2018: Chemical Communications: Chem Comm
Barbara Demmig-Adams, Jared J Stewart, Christopher R Baker, William W Adams
We review the role of a family of transcription factors and their regulons in maintaining high photosynthetic performance across a range of challenging environments with a focus on extreme temperatures and water availability. Specifically, these transcription factors include CBFs (C-repeat binding factors) and DREBs (dehydration-responsive element-binding), with CBF/DREB1 primarily orchestrating cold adaptation and other DREBs serving in heat, drought, and salinity adaptation. The central role of these modulators in plant performance under challenging environments is based on (i) interweaving of these regulators with other key signaling networks (plant hormones and redox signals) as well as (ii) their function in integrating responses across the whole plant, from light-harvesting and sugar-production in the leaf to foliar sugar export and water import and on to the plant's sugar-consuming sinks (growth, storage, and reproduction)...
March 15, 2018: International Journal of Molecular Sciences
Christina D Cota
Ascidians are increasingly being used as a system for investigating cell biology during development. The extreme genetic and cellular simplicity of ascidian embryos in combination with superior experimental tractability make this an ideal system for in vivo analysis of dynamic cellular processes. Transgenic approaches to cellular and sub-cellular analysis of ascidian development have begun to yield new insights into the mechanisms regulating developmental signaling and morphogenesis. This chapter focuses on the targeted expression of fusion proteins in ascidian embryos and how this technique is being deployed to garner new insights into the cell biology of development...
2018: Advances in Experimental Medicine and Biology
Zongbi Bao, Danyan Xie, Ganggang Chang, Hui Wu, Liangying Li, Wei Zhou, Hailong Wang, Zhiguo Zhang, Huabin Xing, Qiwei Yang, Michael J Zaworotko, Qilong Ren, Banglin Chen
Research on HOFs has been developed for quite a long time; however, those with both established permanent porosities and functional properties are extremely rare due to weak hydrogen-bonding interactions among molecular organic linkers which are much more fragile and difficult to stabilize. Herein, through judiciously combining the superiority of both the moderately stable coordination bonds in MOFs and hydrogen bonds, we have realized a microporous hydrogen-bonded organometallic framework HOF-21, which not only shows permanent porosity but also exhibits highly selective separation performance of C2H2/C2H4 at room temperature...
March 14, 2018: Journal of the American Chemical Society
Liuqi Peng, Xuan Mei, Jun He, Jiekun Xu, Weiku Zhang, Ruizheng Liang, Min Wei, David G Evans, Xue Duan
2D nanomaterials have attracted considerable research interest in drug delivery systems, owing to their intriguing quantum size and surface effect. Herein, Gd3+ -doped monolayered-double-hydroxide (MLDH) nanosheets are prepared via a facile bottom-up synthesis method, with a precisely controlled composition and uniform morphology. MLDH nanosheets as drug carrier are demonstrated in coloading of doxorubicin and indocyanine green (DOX&ICG), with an ultrahigh drug loading content (LC) of 797.36% and an encapsulation efficiency (EE) of 99...
March 14, 2018: Advanced Materials
Ang Qiao, Thomas D Bennett, Haizheng Tao, Andraž Krajnc, Gregor Mali, Cara M Doherty, Aaron W Thornton, John C Mauro, G Neville Greaves, Yuanzheng Yue
Glass-forming ability (GFA) is the ability of a liquid to avoid crystallization during cooling. Metal-organic frameworks (MOFs) are a new class of glass formers ( 1 - 3 ), with hitherto unknown dynamic and thermodynamic properties. We report the discovery of a new series of tetrahedral glass systems, zeolitic imidazolate framework-62 (ZIF-62) [Zn(Im2- x bIm x )], which have ultrahigh GFA, superior to any other known glass formers. This ultrahigh GFA is evidenced by a high viscosity η (105 Pa·s) at the melting temperature T m , a large crystal-glass network density deficit (Δρ/ρg )network , no crystallization in supercooled region on laboratory time scales, a low fragility ( m = 23), an extremely high Poisson's ratio (ν = 0...
March 2018: Science Advances
Ren-Mian Chin, Shinn-Jen Chang, Chia-Chen Li, Cha-Wen Chang, Ruo-Han Yu
HYPOTHESIS: Finding an efficient dispersant for obtaining a good dispersion of 5-nm detonation nanodiamond (DND) is always a challenge. Two newly designed diblock copolymers, both poly(ammonium methacrylate)-block-poly(2-phenoxyethyl acrylate) (PMA-b-PBEA) but with different molar ratios of PMA to PBEA, were proposed to be efficient dispersants in stabilizing the concentrated aqueous suspensions of DND. EXPERIMENTS: The dispersion efficiency of dispersants for DND in aqueous suspensions was studied by the measurements of particle size, sedimentation property, and rheological behavior...
March 7, 2018: Journal of Colloid and Interface Science
Mustafa Kemal Demir, Ozlem Yapıcıer, Teyyub Hasanov, Baran Yılmaz, Türker Kılıç
Extra-axial hydatid disease (HD) is rare and may create a diagnostic challenge. Herein, we report an extremely rare case of calvarial HD with superior sagittal sinus invasion and an extension to the scalp with unusual magnetic resonance imaging findings simulating osteomyelitis and abscess. Recognition of detached endocystic membranes was the most important clue for the correct diagnosis. HD should be included in the differential diagnosis for a patient having a destructive skull lesion with peripheral enhancing extra-axial soft tissue component...
January 1, 2018: Neuroradiology Journal
Guangfa Zhang, Qinghua Zhang, Tiantian Cheng, Xiaoli Zhan, Fengqiu Chen
High durability, low cost, and superior anti-icing and active de-icing multifunctional surface coatings, espeicially in the extreme environment, are highly desired to inhibit and/or eliminate the detriment of icing in many fields, such as automobile, aerospace, and power transmission. Herein, we first report a facile and versatile strategy to prepare novel slippery polyols-infused porous surfaces (SPIPSs) with the inexpensive polyols as the lubricant liquids. These SPIPSs are fabricated by a spray-coating approach based on amino-modified magnetic Fe3O4 nanoparticles (MNP@NH2) and amphiphilic P(Poly(ethylene glycol) methyl ether methacrylate-co-glycidyl methacrylate)) copolymer (P(PEGMA-co-GMA) ) covalent cross-linked hybrids, followed by infusion with various polyols...
March 12, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Alper Çıraklı, Pınar Naile Gürgör, Erdal Uzun, Havva Erdem, Soner Çankaya, Orhan Baş
OBJECTIVES: This study aims to evaluate the potential adverse effects of tranexamic acid (TA) on tendon healing. MATERIALS AND METHODS: Twelve male Wistar-Albino rats (weighing 300 g to 350 g) were used in the study. Rats were divided into two groups. Right legs of the rats were determined as the TA group and left legs as the serum physiologic (SP) group. Bilateral Achilles tenotomy was performed and surgically repaired. For the right side, 1 mL of TA and for the left side, 1 mL of SP were applied...
April 2018: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
Ali Mohtashami, Andrew Kiat, Jane Cross, Robert Simon, Austin Curtin
INTRODUCTION: Abernethy malformations are extremely rare congenital anomalous portosystemic shunts. We report the case of a patient with a rare variant Abernethy malformation between the superior mesenteric vein and left renal vein, associated with a massive jejunal diverticulum. PRESENTATION OF CASE: A 37-year-old Caucasian female presented to our emergency department with severe abdominal pain and proceeded to laparotomy for a presumed small bowel obstruction...
February 27, 2018: International Journal of Surgery Case Reports
Yanping Zhao, Bin Xie, Qiang Liu, Rongguang Luo, Yanna Wan, Karolina Malik, Efrem Civilini
Superior mesenteric arteriovenous fistulae (SMAVF) are extremely rare with no consensus about therapeutic indications and optimal approach. Here we present a case of a symptomatic SMAVF found in a young patient a few years after a penetrating abdominal injury. Following a complex clinical management of the acute status, we successfully managed the fistula with three covered stents in two consecutive endovascular procedures. Technical details of the performed procedures, including the main pitfalls and chosen solutions, have been explored and discussed...
March 5, 2018: Annals of Vascular Surgery
Frank M Davis, Jeremy Albright, Katherine A Gallagher, Hitinder S Gurm, Gerald C Koenig, Theodore Schreiber, P Michael Grossman, Peter K Henke
OBJECTIVES: Acute limb ischemia (ALI) of the lower extremity is a potentially devastating condition that requires urgent and definitive management. This challenging scenario is often treated with endovascular, open surgical, or hybrid revascularization in an urgent basis, but the comparative effects of such therapies remain poorly defined. The purpose of this study was to compare outcomes of endovascular, open surgical, and hybrid revascularization for ALI in the contemporary era. METHODS: A large statewide cardiovascular consortium of 45 hospitals was queried for patients between January 2012 and June 2015 who underwent an endovascular, open surgical, or hybrid revascularization for ALI deemed at high risk of limb loss if not treated within 24 hours (Rutherford class IIA or IIB)...
March 5, 2018: Annals of Vascular Surgery
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