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https://www.readbyqxmd.com/read/28427975/surgical-management-of-vertex-epidural-hematoma-technical-case-report-and-literature-review
#1
David T Fernandes-Cabral, Ali Kooshkabadi, Sandip S Panesar, Emrah Celtikci, Hamid Borghei-Razavi, Pinar Celtikci, Juan C Fernandez-Miranda
BACKGROUND: Vertex epidural hematoma (VEH) is an uncommon presentation of extra-axial hematomas. It can represent a surgical dilemma regarding when and how to operate, particularly considering the potential implication of the superior sagittal sinus (SSS). OBJECTIVE: Here, we illustrate the surgical technique for VEH as well as review of the existing literature. METHODS: A 60-year-old male sustained a ground level fall resulting in complete diastasis of the sagittal suture with underlying large VEH causing significant mass effect on the SSS and bi-hemispheric convexities...
April 17, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28426465/neoadjuvant-treatment-a-novel-standard
#2
Sandro Pasquali, Elena Palassini, Silvia Stacchiotti, Paolo G Casali, Alessandro Gronchi
PURPOSE OF REVIEW: The aim of this study was to summarize developments in the adjuvant/neoadjuvant chemotherapy of high-risk adult-type soft tissue sarcomas (STS). RECENT FINDINGS: The role of adjuvant/neaodjuvant chemotherapy in these patients is controversial, with a meta-analysis suggesting a 10% survival benefit. Recently, a randomized controlled trial in high-risk STS of extremities and trunk wall showed a 20% improvement in progression-free and overall survival after three preoperative cycles of epirubicin along with ifosfamide compared with a histology-tailored chemotherapy...
April 19, 2017: Current Opinion in Oncology
https://www.readbyqxmd.com/read/28417577/metal-hydride-nanoparticles-with-ultrahigh-structural-stability-and-hydrogen-storage-activity-derived-from-microencapsulated-nanoconfinement
#3
Jiguang Zhang, Yunfeng Zhu, Huaijun Lin, Yana Liu, Yao Zhang, Shenyang Li, Zhongliang Ma, Liquan Li
Metal hydrides (MHs) have recently been designed for hydrogen sensors, switchable mirrors, rechargeable batteries, and other energy-storage and conversion-related applications. The demands of MHs, particular fast hydrogen absorption/desorption kinetics, have brought their sizes to nanoscale. However, the nanostructured MHs generally suffer from surface passivation and low aggregation-resisting structural stability upon absorption/desorption. This study reports a novel strategy named microencapsulated nanoconfinement to realize local synthesis of nano-MHs, which possess ultrahigh structural stability and superior desorption kinetics...
April 18, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28416834/-efficacy-of-transforaminal-endoscopic-nerve-root-decompression-in-the-treatment-of-degenerative-lumbar-spinal-stenosis
#4
Z R Yu, C D Li, S N Zhu, H L Sun, Y Zhao, L T Qi
OBJECTIVE: To evaluate the feasibility of transforaminal endoscopic nerve root decompression for degenerative lumbar spinal stenosis (DLSS). METHODS: From July 2011 to April 2016, 96 cases of single segment DLSS were involved. All the patients had unilateral lower extremity neurological symptoms, signs, neurogenic intermittent claudication of less than 500 m. Imaging examinations (CT or MRI) or diagnostic nerve root block confirmed single segment degeneration. The mean age was (71...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28414997/successful-treatment-of-nonocclusive-mesenteric-ischemia-after-aortic-valve-replacement-with-continuous-arterial-alprostadil-infusion-a-case-report
#5
Kunio Ogi, Masamitsu Sanui, Yusuke Iizuka, Akinori Aomatsu, Ikue Nakashima, Kohei Hamamoto, Tomohisa Okochi, Alan K Lefor
INTRODUCTION: Nonocclusive mesenteric ischemia (NOMI) after surgery has an extremely poor prognosis with a mortality rate of 30-100%. We report a patient with NOMI following aortic valve replacement who failed to improve despite continuous intra-arterial infusion of papaverine, but was successfully treated with alprostadil (prostaglandin E1 [PGE1]) infusion. PRESENTATION OF CASE: The patient is a 77-year-old man who underwent aortic valve replacement. Due to elevated serum lactate levels five hours after intensive care unit admission, superior mesenteric arteriography was performed, establishing the diagnosis of NOMI...
March 30, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28414671/three-s-a-crowd-an-extremely-rare-case-of-cor-triatriatum-dexter
#6
A Elagizi, R Marvin, G O'Bryan, V Vyas, L Arcement
INTRODUCTION: Cor triatriatum is a congenital cardiac anomaly in which the left (sinister) or right (dexter) atrium is divided into two compartments by residual embryonic tissue, resulting in a tri-atrial heart. As cor triatriatum dextrum can present clinically in various ways and have multiple associated cardiac anomalies, this report attempts to contribute to what is known about this exceedingly rare disorder. CASE: A 40 year old Hispanic man with a medical history of gastritis presented with complaints of palpitations, dizziness and bilateral lower extremity edema...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28409377/laparoscopic-radical-antegrade-modular-pancreatosplenectomy-for-left-sided-pancreatic-cancer-using-the-ligament-of-treitz-approach
#7
Yusuke Ome, Kazuki Hashida, Mitsuru Yokota, Yoshio Nagahisa, Okabe Michio, Kazuyuki Kawamoto
BACKGROUND: Laparoscopic distal pancreatectomy (Lap-DP) for benign lesions or those with low malignant potential has been proven safe and effective, and its performance is now widespread [1-3]. Lap-DP for left-sided pancreatic cancer (PC) is also being increasingly performed. According to some reports, Lap-DP has superior short-term outcomes (blood loss, postoperative hospital stay) and comparable oncological outcomes and overall survival with those of open distal pancreatectomy (Op-DP) [4-6]...
April 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28409112/plasticity-of-premotor-cortico-muscular-coherence-in-severely-impaired-stroke-patients-with-hand-paralysis
#8
Paolo Belardinelli, Leonard Laer, Erick Ortiz, Christoph Braun, Alireza Gharabaghi
Motor recovery in severely impaired stroke patients is often very limited. To refine therapeutic interventions for regaining motor control in this patient group, the functionally relevant mechanisms of neuronal plasticity need to be detected. Cortico-muscular coherence (CMC) may provide physiological and topographic insights to achieve this goal. Synchronizing limb movements to motor-related brain activation is hypothesized to reestablish cortico-motor control indexed by CMC. In the present study, right-handed, chronic stroke patients with right-hemispheric lesions and left hand paralysis participated in a four-week training for their left upper extremity...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28403564/location-of-residual-viable-tumor-cells-after-neoadjuvant-chemotherapy-a-new-concept-with-high-prognostic-performance-in-osteosarcoma
#9
Seung Hyun Kim, Kyoo-Ho Shin, Seong-Hwan Moon, Youngho Kong, Jin-Suck Suh, Woo-Ick Yang
BACKGROUND AND OBJECTIVES: The purpose of this study was to establish a new concept for evaluating responses to neoadjuvant chemotherapy in osteosarcoma. METHODS: A total of 56 high-grade extremity osteosarcoma patients were retrospectively reviewed. A new conceptual method was derived from locations of residual viable tumor cells (LRVTC) after chemotherapy, whether extracompartmental or intracompartmental, rather than quantitative measurements of necrosis rates of tumor cells...
April 12, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28397434/the-dufourmentel-modification-of-the-limberg-flap-does-it-fit-all
#10
Maciej Sebastian, Maciej Sroczyński, Jerzy Rudnicki
BACKGROUND: Pilonidal disease is a common problem, especially in young adults. Therapy for the acute disease involves abscess incision and drainage. Treatment of the chronic disease is more complicated, due to the variety of methods and relatively high recurrence rate after surgical therapy. OBJECTIVES: The aim of this study was to investigate the effects of the Dufourmentel modification of the Limberg flap in the treatment of pilonidal disease. MATERIAL AND METHODS: The study involved 37 cases of chronic pilonidal disease that were operated on by the method presented...
January 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28389547/engineering-of-bacteriophages-y2-dpol1-c-and-y2-luxab-for-efficient-control-and-rapid-detection-of-the-fire-blight-pathogen-erwinia-amylovora
#11
Yannick Born, Lars Fieseler, Valentin Thöny, Nadja Leimer, Brion Duffy, Martin J Loessner
Erwinia amylovora is the causative agent of fire blight, a devastating plant disease affecting members of the Rosaceae Alternatives to antibiotics for control of fire blight symptoms and outbreaks are highly desirable, due to increasing drug-resistance and tight regulatory restrictions. Moreover, the available diagnostic methods either lack sensitivity, speed, or are unable to discriminate between live and dead bacteria. Owing to their extreme biological specificity, bacteriophages are promising alternatives for both aims...
April 7, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28389489/long-term-effect-of-smartphone-delivered-interval-walking-training-on-physical-activity-in-patients-with-type-2-diabetes-protocol-for-a-parallel-group-single-blinded-randomised-controlled-trial
#12
Laura Staun Valentiner, Mathias Ried-Larsen, Kristian Karstoft, Cecilie Fau Brinkløv, Charlotte Brøns, Rasmus Oestergaard Nielsen, Robin Christensen, Jens Steen Nielsen, Allan Arthur Vaag, Bente Klarlund Pedersen, Henning Langberg
INTRODUCTION: Physical activity is a cornerstone in type 2 diabetes (T2D) rehabilitation. Effective long-term and low-cost strategies to keep these patients' physically active are needed. However, maintaining physical activity behaviour is difficult once formalised interventions end. Structured exercise training supported by mobile technology and remote feedback is potentially an effective strategy. The objective of the trial is to investigate whether mobile health support using the InterWalk application for smartphones is effective in increasing physical activity levels in persons with T2D over time compared with standard care...
April 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28388638/mechanisms-causing-size-differences-of-the-land-hermit-crab-coenobita-rugosus-among-eco-islands-in-southern-taiwan
#13
Chia-Hsuan Hsu, Keryea Soong
Numerous environmental factors can influence body size. Comparing populations in different ecological contexts is one potential approach to elucidating the most critical of such factors. In the current study, we found that the body size of the land hermit crab Coenobita rugosus was significantly larger on Dongsha Island in the South China Sea than on other eco-islands around Southern Taiwan. We hypothesized that this could be due to differences in (1) shell resources, (2) parasite impact, (3) competition, (4) predation, and (5) food...
2017: PloS One
https://www.readbyqxmd.com/read/28386743/anomalous-inferior-mesenteric-artery-supplying-the-ascending-transverse-descending-and-sigmoid-colons
#14
Tamami Abe, Ayako Ujiie, Yuya Taguchi, Shun Satoh, Takahiro Shibuya, Yan Jun, Sumio Isogai, Yoh-Ichi Satoh
We have encountered in our anatomical practice the first case and an extremely rare second case in which the ascending, transverse, descending, and sigmoid colons were supplied by the inferior mesenteric artery. The causes of colic artery anomalies are generally explained in conjunction with the development of the superior mesenteric artery, which is intimately related to embryonic elongation and midgut rotation. However, this embryological model was inapplicable to both cases. This difficulty motivated us to seek possible relationships with reported anomalous inferior mesenteric arteries in adults as well as their embryological causes...
April 6, 2017: Anatomical Science International
https://www.readbyqxmd.com/read/28382980/background-free-search-for-neutrinoless-double-%C3%AE-decay-of-76-ge-with-gerda
#15
(no author information available yet)
Many extensions of the Standard Model of particle physics explain the dominance of matter over antimatter in our Universe by neutrinos being their own antiparticles. This would imply the existence of neutrinoless double-β decay, which is an extremely rare lepton-number-violating radioactive decay process whose detection requires the utmost background suppression. Among the programmes that aim to detect this decay, the GERDA Collaboration is searching for neutrinoless double-β decay of (76)Ge by operating bare detectors, made of germanium with an enriched (76)Ge fraction, in liquid argon...
April 5, 2017: Nature
https://www.readbyqxmd.com/read/28382296/spontaneous-dissections-of-multiple-visceral-arteries-an-extremely-rare-case
#16
Trong Binh Le, Yong Sun Jeon, Kee Chun Hong, Soon Gu Cho, Keun-Myoung Park
Spontaneous dissections of visceral arteries without aortic involvement are very rare. The etiologies of these entities are unclear and their clinical managements remain controversial. We report a case of spontaneous multiple dissections affecting 4 visceral arteries including the superior mesenteric artery, the celiac artery and the bilateral renal arteries. The patient was managed conservatively and endovascularly. The clinical manifestation markedly improved and laboratory tests returned to normal limits within 1 week...
April 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28376148/adaptive-clinical-trials-advantages-and-disadvantages-of-various-adaptive-design-elements
#17
Edward L Korn, Boris Freidlin
There is a wide range of adaptive elements of clinical trial design (some old and some new), with differing advantages and disadvantages. Classical interim monitoring, which adapts the design based on early evidence of superiority or futility of a treatment arm, has long been known to be extremely useful. A more recent application of interim monitoring is in the use of phase II/III designs, which can be very effective (especially in the setting of multiple experimental treatments and a reliable intermediate end point) but do have the cost of having to commit earlier to the phase III question than if separate phase II and phase III trials were performed...
June 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28375910/dizziness-in-the-outpatient-care-setting
#18
Terry D Fife
PURPOSE OF REVIEW: This article summarizes an approach to evaluating dizziness for the general neurologist and reviews common and important causes of dizziness and vertigo. RECENT FINDINGS: Improved methods of diagnosing patients with vertigo and dizziness have been evolving, including additional diagnostic criteria and characterization of some common conditions that cause dizziness (eg, vestibular migraine, benign paroxysmal positional vertigo, chronic subjective dizziness)...
April 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28373261/how-we-treat-central-venous-access-device-related-upper-extremity-dvt
#19
Anita Rajasekhar, Michael B Streiff
Central venous access device (CVAD)-related thrombosis (CRT) is a common complication among patients requiring central venous access as part of their medical care. Complications of CRT include pulmonary embolism, recurrent deep venous thrombosis, loss of central venous access and post-thrombotic syndrome. Patient, device and treatment-related factors can influence the risk of CRT. Despite numerous randomized controlled trials, the clinical benefit of pharmacologic thromboprophylaxis for prevention of CRT remains to be established...
April 3, 2017: Blood
https://www.readbyqxmd.com/read/28371868/immediate-pain-relief-in-adhesive-capsulitis-by-acupuncture-a-randomized-controlled-double-blinded-study
#20
Sven Schröder, Gesa Meyer-Hamme, Thomas Friedemann, Sebastian Kirch, Michael Hauck, Rosemarie Plaetke, Sunja Friedrichs, Amit Gulati, Daniel Briem
Objective.:  Primary adhesive capsulitis (AC), or frozen shoulder, is an insidious and idiopathic disease. Severe pain is predominant in the first two of the three stages of the condition, which can last up to 21 months. Design, Setting, and Subjects.:  Sixty volunteers with primary AC were randomly assigned to acupuncture with press tack needles compared with press tack placebos in a patient- and observer-blinded placebo-controlled study. The participants were subsequently offered classical needle acupuncture in an open follow-up clinical application...
March 20, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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