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https://www.readbyqxmd.com/read/28110516/the-social-determinants-and-starting-and-sustaining-quit-attempts-in-a-national-sample-of-aboriginal-and-torres-strait-islander-smokers
#1
David P Thomas, Kathryn S Panaretto, Maureen Davey, Viki Briggs, Ron Borland
OBJECTIVE: To assess whether social, economic and demographic measures are associated with initiating and sustaining quit attempts in a national sample of Aboriginal and Torres Strait Islander smokers. METHODS: We analysed data from 759 adults who reported smoking at least weekly in the Talking About The Smokes baseline survey (April 2012 - October 2013) and completed a follow up survey a year later (August 2013 - August 2014). RESULTS: Almost none of the standard baseline socioeconomic indicators predicted making or sustaining quit attempts...
January 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28110507/computer-assisted-quantification-of-cd3-t-cells-in-follicular-lymphoma
#2
Fazly S Abas, Arwa Shana'ah, Beth Christian, Robert Hasserjian, Abner Louissaint, Michael Pennell, Berkman Sahiner, Weijie Chen, Muhammad Khalid Khan Niazi, Gerard Lozanski, Metin Gurcan
The advance of high resolution digital scans of pathology slides allowed development of computer based image analysis algorithms that may help pathologists in IHC stains quantification. While very promising, these methods require further refinement before they are implemented in routine clinical setting. Particularly critical is to evaluate algorithm performance in a setting similar to current clinical practice. In this article, we present a pilot study that evaluates the use of a computerized cell quantification method in the clinical estimation of CD3 positive (CD3+) T cells in follicular lymphoma (FL)...
January 22, 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/28110465/spectroscopic-physicochemical-and-photophysical-investigation-of-biologically-active-2-oxo-quinoline-3-carbonitrile-derivative
#3
Mohie E M Zayed, Parveen Kumar
4-(2,3,4-trimethoxyphenyl)-8-methoxy-2-oxo-1,2,5,6 tetrahydrobenzo [h] quinoline-3-carbonitrile (TMTQ) dye was synthesized by one-pot multicomponent reactions (MCRs) of 2,3,4 trimethoxybenzaldehyd, ethyl cyanoacetate, 6-methoxy-1,2,3,4-tetrahydro-naphthalin-1-one and ammonium acetate under microwave irradiation. The structures of the synthesized compound was established by spectroscopic (FT-IR, (1)H-NMR, (13)C-NMR, EI-MS) and elemental analysis. In addition, spectroscopic and physicochemical parameters, including electronic absorption, excitation coefficient, Stokes shift, oscillator strength, transition dipole moment and fluorescence quantum yield have investigated in order to explore the analytical potential of synthesized compounds...
January 21, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28110461/the-emerging-role-of-liquid-biopsies-circulating-tumor-cells-and-circulating-cell-free-tumor-dna-in-lung-cancer-diagnosis-and-identification-of-resistance-mutations
#4
REVIEW
Angela Esposito, Carmen Criscitiello, Dario Trapani, Giuseppe Curigliano
Therapeutic advances in the treatment of lung cancer are in part due to a more complete understanding of its genomic portrait. The serial monitoring of tumor genotypes, which are instable and prone to changes under selective pressure, is becoming increasingly needed. Although tumor biopsies remain the reference standard for the diagnosis and genotyping of lung cancer, they are invasive and not always feasible. The "liquid biopsies" have the potential to overcome many of these hurdles, allowing a rapid and accurate identification of de novo and resistant genetic alterations and a real-time monitoring of treatment responses...
January 2017: Current Oncology Reports
https://www.readbyqxmd.com/read/28110428/exploring-relationship-between-spiritual-intelligence-religiosity-and-life-satisfaction-among-elderly-pakistani-muslims
#5
Khadeeja Munawar, Omama Tariq
This study is an effort to explore the relationship between spiritual intelligence, religiosity and life satisfaction in elderly Pakistani Muslims. A non-probability purposive sampling technique is utilized in order to recruit a sample of 100 elderly people (n = 50 men; n = 50 = women). Standardized questionnaires were used for collecting data. Data analysis was carried out using Pearson product-moment correlation analysis and independent sample t test. Findings revealed a significant correlation between spiritual intelligence, religiosity and life satisfaction among Pakistani elderly Muslim people...
January 21, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28110419/patients-trust-in-physician-patient-enablement-and-health-related-quality-of-life-during-colon-cancer-treatment
#6
Nicole Ernstmann, Markus Wirtz, Anika Nitzsche, Sophie E Gross, Lena Ansmann, Tristan D Gloede, Julia Jung, Holger Pfaff, Walter Baumann, Stephan Schmitz, Melanie Neumann
In cancer care, where patients and their families experience significant emotional distress and patients have to deal with complex medical information, patient centeredness is an important aspect of quality of care. The aim of this study is to examine the impact of patients' trust in their oncologists and patients' enablement on changes in health-related quality of life of colon cancer patients during follow-up care. We conducted a prospective study in a representative sample of private practices of German oncologists (N = 44)...
January 21, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28110412/prevention-of-cardiac-surgery-associated-aki-by-implementing-the-kdigo-guidelines-in-high-risk-patients-identified-by-biomarkers-the-prevaki-randomized-controlled-trial
#7
Melanie Meersch, Christoph Schmidt, Andreas Hoffmeier, Hugo Van Aken, Carola Wempe, Joachim Gerss, Alexander Zarbock
PURPOSE: Care bundles are recommended in patients at high risk for acute kidney injury (AKI), although they have not been proven to improve outcomes. We sought to establish the efficacy of an implementation of the Kidney Disease Improving Global Outcomes (KDIGO) guidelines to prevent cardiac surgery-associated AKI in high risk patients defined by renal biomarkers. METHODS: In this single-center trial, we examined the effect of a "KDIGO bundle" consisting of optimization of volume status and hemodynamics, avoidance of nephrotoxic drugs, and preventing hyperglycemia in high risk patients defined as urinary [TIMP-2]·[IGFBP7] > 0...
January 21, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28110407/in-vitro-performance-of-cad-cam-fabricated-implant-supported-temporary-crowns
#8
Martin Rosentritt, Philipp Raab, Sebastian Hahnel, Matthias Stöckle, Verena Preis
OBJECTIVES: The aim of this study was to investigate the in-vitro performance and fracture resistance of a temporary computer-aided designed and computer-aided manufactured polymethylmethacrylate (CAD/CAM-PMMA) material as implant or tooth-supported single crown with respect to the clinical procedure (permanently bonded/temporarily cemented). MATERIALS AND METHODS: Sixty-four crowns were fabricated on implants or human molar teeth simulating (a) labside procedure on prefabricated titanium-bonding base ([TiBase] implant crown bonded in laboratory, screwed chairside), (b) labside procedure ([LAB] standard abutment and implant crown bonded in laboratory, screwed chairside), (c) chairside procedure ([CHAIR] implant crown bonded to abutment), and (d) reference ([TOOTH] crowns luted on prepared human teeth)...
January 21, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28110381/minimal-residual-disease-in-acute-myeloid-leukemia
#9
REVIEW
Pamela J Sung, Selina M Luger
New technology and improved understanding of the pathogenesis of acute leukemias have allowed for sensitive detection of minimal residual disease (MRD). Despite many years of research demonstrating the prognostic value of MRD, there is no standard of care for measurement of MRD in acute myeloid leukemia. The techniques for assessment are continuing to improve at a rapid pace; however, the benefit of risk-adapted approaches for MRD positive disease remains a major question. This review focuses on recent methodological advances for MRD detection, the role of MRD in prognostication, and current application of the available evidence in guiding therapy decisions...
January 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28110380/iscev-standard-for-clinical-electro-oculography-2017-update
#10
Paul A Constable, Michael Bach, Laura J Frishman, Brett G Jeffrey, Anthony G Robson
The clinical electro-oculogram (EOG) is an electrophysiological test of the outer retina and retinal pigment epithelium (RPE) in which changes in the electrical potential across the RPE are recorded during successive periods of dark and light adaptation. This document presents the 2017 EOG Standard from the International Society for Clinical Electrophysiology of Vision (ISCEV: www.iscev.org ). This standard has been reorganized and updated to include an explanation of the mechanism of the EOG, but without substantive changes to the testing protocol from the previous version published in 2011...
January 21, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28110377/sulfasalazine-in-prevention-of-pouchitis-after-proctocolectomy-with-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#11
Eleonora Scaioli, Alessandro Sartini, Elisa Liverani, Richard John Digby, Giampaolo Ugolini, Giancarlo Rosati, Gilberto Poggioli, Davide Festi, Franco Bazzoli, Andrea Belluzzi
BACKGROUND: Pouchitis is the most frequent complication after ileal pouch-anal anastomosis for refractory ulcerative colitis. A non-standardized preventative treatment exists. Sulfasalazine has proved effective in acute pouchitis therapy. AIMS: The aim of this study was to retrospectively evaluate the effect of sulfasalazine in primary prophylaxis of pouchitis after proctocolectomy with ileal pouch-anal anastomosis. METHODS: Data files of patients who underwent total proctocolectomy with ileal pouch-anal anastomosis for refractory ulcerative colitis and/or dysplasia from January 2007 to December 2014, with a follow-up until August 2015, were analyzed...
January 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28110367/accurate-simultaneous-quantification-of-liver-steatosis-and-iron-overload-in-diffuse-liver-diseases-with-mri
#12
Manuela França, Ángel Alberich-Bayarri, Luis Martí-Bonmatí, Pedro Oliveira, Francisca Emanuel Costa, Graça Porto, José Ramón Vizcaíno, Javier Sanchez Gonzalez, Eduardo Ribeiro, João Oliveira, Helena Pessegueiro Miranda
PURPOSE: To evaluate the diagnostic performances of 3 Tesla multi-echo chemical shift-encoded gradient echo magnetic resonance (MECSE-MR) imaging to simultaneously quantify liver steatosis and iron overload in a wide spectrum of diffuse liver diseases having biopsy as reference standard. METHODS: MECSE-MR-acquired images were used to calculate fat fraction and iron content in a single breath-hold in 109 adult patients. Proton density fat fraction (PDFF) was prospectively estimated using complex-based data reconstruction with multipeak fat modeling...
January 21, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28110366/atomoxetine-treatment-for-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-adhd-a-comprehensive-meta-analysis-of-outcomes-on-parent-rated-core-symptomatology
#13
REVIEW
Jessica L Gayleard, Matthew P Mychailyszyn
Attention-Deficit/Hyperactivity Disorder (ADHD) impacts a significant number of children and adolescents and often leads to deleterious functional impairment. Psychostimulant medication has historically been the first line of pharmacological intervention, though recent years have seen greater attention paid to non-stimulant alternatives. The objective of the present study was to conduct the most comprehensive meta-analysis to date evaluating the efficacy of atomoxetine in reducing core symptomatology of ADHD according to parent report...
January 21, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28110356/predicting-conversion-to-glaucoma-using-standard-automated-perimetry-and-frequency-doubling-technology
#14
Genichiro Takahashi, Shaban Demirel, Chris A Johnson
PURPOSE: To test the hypothesis that development of glaucomatous visual fields can be predicted several years earlier from prior visual field information. METHODS: One-hundred and seven eyes with glaucomatous optic neuropathy (n = 47 eyes) or which were suspicious for glaucoma (n = 60) were prospectively enrolled in a longitudinal study. Visual fields were evaluated on an annual basis using standard automated perimetry (SAP), the original version of frequency doubling technology (FDT) perimetry, and a custom version of FDT that used the 24-2 stimulus pattern...
January 21, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28110351/determining-lead-cadmium-and-mercury-in-cosmetics-using-sweeping-via-dynamic-chelation-by-capillary-electrophoresis
#15
Kuan-Ling Chen, Shiuh-Jen Jiang, Yen-Ling Chen
International limits have been established for metal impurities in cosmetics to prevent overexposure to heavy metal ions. Sweeping via dynamic chelation was developed using capillary electrophoresis to analyze lead (Pb), cadmium (Cd) and mercury (Hg) impurities in cosmetics. The sweeping via dynamic chelation mechanism involves a large volume of metal ions being swept by a small quantity of chelating agents that were electrokinetically injected into the capillary to chelate metal ions and increase the detection sensitivity...
January 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28110328/impact-of-medical-tv-shows-on-preprocedural-fear-of-surgical-in-house-patients
#16
Kai Witzel, Horst J Koch, Cornelia Kaminski
: Background and Hypotheses: The growing number of medical television series and the increasing amount of time people spend watching TV will have an influence on what they expect from their treatment in a hospital. We suspect that reality as presented in the media and the actual reality of hospitals are not always conceived of as two different worlds. Many medical TV shows present dramatic, life-threatening operations much more often than they occur in reality. Patients who frequently watch such shows might be induced to believe that even routine operations are often dangerous, which could result in higher levels of fear before such an operation...
January 21, 2017: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/28110322/classification-of-facial-wrinkles-among-chinese-women
#17
Zhang Jiechen, Hou Wei, Feng Suying, Chen Xiangsheng, Wang Hongwei
It is generally recognized that Caucasians and Asians have different skin aging features. The aim of this study was to develop a facial wrinkle grading scale for Chinese women. Standard photographs were taken of 242 Chinese women. Six sets of 0 to 9 wrinkle scales with reference photographs and descriptions were selected, including grading scales for resting and hyperkinetic crow's feet, frontalis lines, glabellar frown lines, and nasolabial folds. To identify the scale by objective quantitative measurement, skin surface measurements from the Visioscan(®) VC98 were used...
October 17, 2016: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28110298/idh1-mutation-in-diffuse-gliomas-in-persons-age-55-years-and-over
#18
Chase Robinson, B K Kleinschmidt-DeMasters
Diffuse astrocytoma (DA), anaplastic astrocytoma (AA), and glioblastoma (GBM) are defined by the World Health Organization (WHO) based on IDH-mutational status. The vast majority of IDH-mutated gliomas (90% of which involve a mutation in IDH1 R132H, which can be assessed by IDH1 immunohistochemistry [IHC]) occur in persons younger than 55 years of age. This raises the question as to the prevalence of IDH-mutant tumors in older persons and whether the gliomas in older patients should be routinely tested. Since January 1, 2014, we have employed a standard screening panel for all gliomas regardless of patient age...
January 21, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28110285/validation-of-a-clinical-screening-instrument-for-tumour-predisposition-syndromes-in-patients-with-childhood-cancer-tups-protocol-for-a-prospective-observational-multicentre-study
#19
Floor A M Postema, Saskia M J Hopman, Corianne A J M de Borgie, Peter Hammond, Raoul C Hennekam, Johannes H M Merks, Cora M Aalfs, Jakob K Anninga, Lieke Pv Berger, Fonnet E Bleeker, Eveline Sjm de Bont, Corianne Ajm de Borgie, Charlotte J Dommering, Natasha Ka van Eijkelenburg, Peter Hammond, Raoul C Hennekam, Marry M van den Heuvel-Eibrink, Saskia Mj Hopman, Marjolijn Cj Jongmans, Wijnanda A Kors, Tom Gw Letteboer, Jan Lcm Loeffen, Johannes Hm Merks, Maran Jw Olderode-Berends, Floor Am Postema, Anja Wagner
INTRODUCTION: Recognising a tumour predisposition syndrome (TPS) in patients with childhood cancer is of significant clinical relevance, as it affects treatment, prognosis and facilitates genetic counselling. Previous studies revealed that only half of the known TPSs are recognised during standard paediatric cancer care. In current medical practice it is impossible to refer every patient with childhood cancer to a clinical geneticist, due to limited capacity for routine genetic consultation...
January 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28110265/comparative-effectiveness-of-two-disparate-policies-on-child-health-experimental-evidence-from-the-philippines
#20
John W Peabody, Stella Quimbo, Jhiedon Florentino, Riti Shimkhada, Xylee Javier, David Paculdo, Dean Jamison, Orville Solon
BACKGROUND  : Should health systems invest more in access to care by expanding insurance coverage or in health care services including improving the quality of care? Comparing these options experimentally would shed light on the impact and cost-effectiveness of these strategies. METHODS  : The Quality Improvement Demonstration Study (QIDS) was a randomized policy experiment conducted across 30 districts in the Philippines. The study had a control group and two policy intervention groups intended to improve the health of young children...
January 20, 2017: Health Policy and Planning
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