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Diverticulosis

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https://www.readbyqxmd.com/read/29623099/treatment-of-diverticular-disease-an-update-on-latest-evidence-and-clinical-implications
#1
REVIEW
Marilia Carabotti, Bruno Annibale
Background: Diverticular disease (DD) is a common condition, especially in Western countries. In about 80% of patients, colonic diverticula remain asymptomatic (diverticulosis), while approximately 20% of patients may develop abdominal symptoms (symptomatic uncomplicated diverticular disease, SUDD) and, eventually complications as acute diverticulitis (AD). The management of this condition has been improved, and in the last five years European countries and the USA have published guidelines and recommendations...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29608808/an-unusual-cause-of-gastrointestinal-bleeding-in-a-hemodialysis-patient
#2
Julien Aron, Aymeric Couturier, Leila Sinayoko, Viviane Duedal, Christophe Ridel, Maxime Touzot
Iron deficiency caused by gastrointestinal (GI) bleeding is a common cause of anemia in hemodialysis patient. Herein, we report the case of an 89-year-old hemodialysis patient who presented with acute anemia and melena. Endoscopy found gastritis and diverticulosis without active bleeding. A capsule endoscopy (CE) was then performed and revealed multiple vascular lesions that lead to the diagnosis of Blue Rubber Bleb Nevus syndrome (BRBNS). This rare disease is associated with multiple venous malformations in the skin and the GI tract, usually observed in children...
April 2, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29607785/the-use-of-probiotics-in-different-phases-of-diverticular-disease
#3
Veronica Ojetti, Carmine Petruzziello, Silvia Cardone, Luisa Saviano, Alessio Migneco, Luca Santarelli, Maurizio Gabrielli, Raffaella Zaccaria, Loris Lopetuso, Marcello Covino, Marcello Candelli, Antonio Gasbarrini, Francesco Franceschi
BACKGROUND & AIMS: Diverticular Disease (DD) is a common clinical condition with a dramatic increasing of the prevalence among industrialized countries. Based on the most used classification, DD may be divided into asymptomatic diverticulosis, symptomatic uncomplicated diverticular disease and complicated diverticular disease. Since recent studies pointed out the role of GUT microbiota imbalance in promoting diverticular formation and inflammation, we have designed a systematic review focusing on the possible role of probiotics in the management of this condition...
April 2, 2018: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/29596124/diverticular-disease-traditional-and-evolving-paradigms
#4
Lenore Lamanna, Patricia E Moran
Diverticular disease includes diverticulosis, which are sac protrusions of the intestinal mucosa, and diverticulitis, inflammation of the diverticula. Diverticular disease is listed as one of the top 10 leading physician diagnoses for gastrointestinal disorders in outpatient clinic visits in the United States. There are several classifications of diverticular disease ranging from asymptomatic diverticulosis to diverticulitis with complications. Several theories are linked to the development of diverticula which includes the physiology of the colon itself, collagen cross-linking, and recently challenged, low-fiber intake...
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
https://www.readbyqxmd.com/read/29563543/an-aberrant-microbiota-is-not-strongly-associated-with-incidental-colonic-diverticulosis
#5
Roshonda B Jones, Anthony A Fodor, Anne F Peery, Matthew C B Tsilimigras, Kathryn Winglee, Amber McCoy, Michael Sioda, Robert S Sandler, Temitope O Keku
Colonic diverticula are protrusions of the mucosa through weak areas of the colonic musculature. The etiology of diverticulosis is poorly understood, but could be related to gut bacteria. Using mucosal biopsies from the sigmoid colon of 226 subjects with and 309 subjects without diverticula during first-time screening colonoscopy, we assessed whether individuals with incidental colonic diverticulosis have alternations in the adherent bacterial communities in the sigmoid colon. We found little evidence of substantial associations between the microbial community and diverticulosis among cases and controls...
March 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29559789/colonic-diverticulosis-is-not-a-risk-factor-for-colonic-adenoma
#6
Wandong Hong, Lemei Dong, Maddalena Zippi, Simon Stock, Wujun Geng, Chunfang Xu, Mengtao Zhou
Background and aims: Colonic diverticulosis may represent a risk factor for colonic adenomas by virtue of the fact that evolving data suggest that these 2 conditions may share common risk factors such as Western dietary pattern and physical inactivity. This study aims to investigate the association between colonic diverticulosis and colonic adenomas in mainland China. Methods: We conducted a cross-sectional study on patients who underwent colonoscopic examination between October 2013 and December 2014 in a university hospital in mainland China...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29541987/the-effect-of-metabolic-syndrome-on-postoperative-outcomes-following-laparoscopic-colectomy
#7
A Zarzavadjian Le Bian, C Denet, N Tabchouri, H Levard, R Besson, T Perniceni, R Costi, P Wind, D Fuks, B Gayet
BACKGROUND: Among the criteria used to diagnose metabolic syndrome (MS), obesity and diabetes mellitus (DM) are associated with poor postoperative outcomes following colectomy. MS is also associated with colorectal cancer (CRC) and diverticulosis, both of which may be treated with colectomy. However, the effect of MS on postoperative outcomes following laparoscopic colectomy has yet to be clarified. METHODS: In an academic tertiary hospital, data from all consecutive patients undergoing laparoscopic colectomy from 2005 to 2014 were prospectively recorded and analysed...
March 14, 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29533249/a-variant-of-col3a1-rs3134646-is-associated-with-risk-of-developing-diverticulosis-in-white-men
#8
Matthias Christian Reichert, Juozas Kupcinskas, Marcin Krawczyk, Christoph Jüngst, Markus Casper, Frank Grünhage, Beate Appenrodt, Vincent Zimmer, Susanne Nicole Weber, Algimantas Tamelis, Jaune Ieva Lukosiene, Neringa Pauziene, Gediminas Kiudelis, Laimas Jonaitis, Christoph Schramm, Tobias Goeser, Antje Schulz, Maciej Malinowski, Matthias Glanemann, Limas Kupcinskas, Frank Lammert
BACKGROUND: Colonic diverticulosis is one of the most common gastroenterological disorders. Although diverticulosis is typically benign, many individuals develop diverticulitis or other aspects of diverticular disease. Diverticulosis is thought to stem from a complex interaction of environmental, dietary, and genetic factors; however, the contributing genetic factors remain unknown. OBJECTIVE: The aim of our present study was to determine the role of genetic variants within genes encoding for collagens of the connective tissue in diverticulosis...
May 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29525374/evaluation-and-management-of-lower-gastrointestinal-bleeding
#9
REVIEW
Aun Raza Shah, Vikram Jala, Hammad Arshad, Mohammad Bilal
Lower gastrointestinal bleeding (LGIB) is a common cause of presentation to the emergency department and hospital admissions. The incidence of LGIB increases with age and the most common etiologies are diverticulosis, angiodysplasia, malignancy and anorectal diseases. Foremost modality for evaluation and treatment of LGIB is colonosopy. Other diagnostic tools such as nuclear scintigraphy, computed tomography, angiography and capsule endoscopy are also frequently used in the workup of LGIB. Choice of treatment modality depends on the hemodynamic status of the patient, rate of bleeding, expertise and available resources...
March 7, 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29521829/obesity-and-the-risk-of-colonic-diverticulosis-a-meta-analysis
#10
Karn Wijarnpreecha, Wasin Ahuja, Supavit Chesdachai, Charat Thongprayoon, Veeravich Jaruvongvanich, Wisit Cheungpasitporn, Patompong Ungprasert
BACKGROUND: The possible relationship between obesity and the risk of colonic diverticulosis has been suggested by recent epidemiologic studies, although the results were inconsistent. OBJECTIVE: This systematic review and meta-analysis was conducted to summarize all of the available data. DATA SOURCES: A comprehensive literature review was conducted using the MEDLINE and EMBASE databases through January 2017. STUDY SELECTION: Studies that compared the risk of colonic diverticulosis among subjects with obesity versus those without obesity were included...
April 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29520457/risk-factors-associated-with-longer-cecal-intubation-time-a-systematic-review-and-meta-analysis
#11
REVIEW
Veeravich Jaruvongvanich, Tomoki Sempokuya, Passisd Laoveeravat, Patompong Ungprasert
PURPOSE: Cecal intubation time (CIT) is an indicator for difficult colonoscopy which is associated with patients' unpleasant experience as well as increased risk of complications. Several studies have attempted to identify predictors for prolonged CIT but those studies tended to be small which gave rise to inconsistent and underpowered results. This systematic review and meta-analysis was conducted to summarize all available data. METHODS: MEDLINE and EMBASE databases were searched through November 2017 for studies that investigated the factors for prolonged CIT...
March 9, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29511540/a-systematic-review-of-gallstone-sigmoid-ileus-management
#12
REVIEW
Nicholas Farkas, Vasha Kaur, Arun Shanmuganandan, John Black, Chantal Redon, Adam E Frampton, Nicholas West
Introduction: Gallstone sigmoid ileus is a rare although serious complication of cholelithiasis resulting in large bowel obstruction. The condition accounts for 4% of all gallstone ileus patients. There are no recognized management guidelines currently. Management strategies range from minimally invasive endoscopy and lithotripsy to substantial surgery. We aim to identify trends when managing patients with gallstone sigmoid ileus to help improve outcomes. Methods: Literature searches of EMBASE, Medline and by hand were conducted...
March 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29505648/diverticular-disease-the-old-the-new-and-the-ever-changing-view
#13
Michael S DiSiena, John W Birk
Our understanding of diverticular disease has evolved significantly during the last 25 years, and as such, a reexamination is in order. We performed a literature search for the years 1960-2017 of PubMed, Medline, and Google Scholar for updates regarding the epidemiology, risk factors, and therapies for traditional diverticulitis as well as the recently described subtypes of diverticular disease, segmental colitis associated with diverticulosis, and symptomatic uncomplicated diverticular disease. Although the prevalence of diverticulosis is still extremely common in the general population, the literature suggests that the incidence of diverticulitis is much less than previously believed and occurrences do not necessarily increase with age...
March 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29500612/-diverticular-disease-complications-and-differential-diagnosis
#14
REVIEW
A G Schreyer
BACKGROUND: Diverticular disease is becoming increasingly more common in the western world. It is clinically subdivided into uncomplicated diverticular disease and diverticular disease with a complicated course. In approximately 20% of cases the diverticula will become symptomatic during the lifetime of patients. RESULTS: In contrast to previous medical opinions, the occurrence of diverticula cannot be prevented by a diet rich in fiber; however, the development into complicated diverticulitis can be reduced by dietary measures...
April 2018: Der Radiologe
https://www.readbyqxmd.com/read/29487638/complicated-jejunal-diverticulitis-with-unusual-presentation
#15
Dinesh Kumar, Meenakshi
Jejunal diverticulosis is usually an asymptomatic condition characterized by herniation of mucosa through sites of weakening on the mesenteric border of the jejunum, leading to variable number of discrete outpouchings from the bowel. They are usually discovered incidentally on imaging or surgery done for some other reason. Complications such as diverticulitis with perforation and bowel obstruction and life-threatening gastrointestinal bleeding are rare. Our review highlights the correlation between radiological and surgical findings in 2 different cases of complicated jejunal diverticulitis...
February 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29432700/relationship-between-diverticulosis-and-nonalcoholic-fatty-liver-disease-in-elderly-patients
#16
Abdurrahman Sahin, Nurettin Tunc, Ulvi Demirel, Orhan Kursat Poyrazoglu, Mehmet Yalniz, Ibrahim Halil Bahcecioglu
Objective To compare clinical and laboratory features of elderly patients with and without diverticulosis and assess factors related to hepatosteatosis. Method This retrospective case-control study analysed the clinical and laboratory data, colonoscopy and abdominal ultrasonography records of patients >65 years who underwent colonoscopies. Subjects were categorized according to the presence and absence of colonic diverticulosis. Univariate/multivariate logistic regression analyses were performed to evaluate the independent predictive factors of hepatosteatosis...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29411119/selective-association-of-nonaspirin-nsaids-with-risk-of-diverticulitis
#17
Matthias C Reichert, Marcin Krawczyk, Beate Appenrodt, Markus Casper, Bettina Friesenhahn-Ochs, Frank Grünhage, Christoph Jüngst, Vincent Zimmer, Frank Lammert, Marc Dauer
PURPOSE: The purpose of this study is to investigate the association of intake of nonsteroidal anti-inflammatory drugs (NSAIDs) and in particular nonaspirin NSAIDs and compare it with other risk factors for the progression of diverticulosis to diverticulitis in patients who underwent colonoscopy. METHODS: A total of 194 patients who underwent complete colonoscopy in our center between 2012 and 2016 were recruited: 144 with diverticulosis without prior diverticulitis (median age 71 years, 59...
February 6, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29392152/small-bowel-diverticulosis-and-jejunal-perforation-in-marfan-syndrome
#18
Benjamin S Robey, Anne F Peery, Evan S Dellon
Marfan syndrome is an autosomal dominant disorder involving mutation in the FBN1 gene, which encodes fibrillin-1, a protein critical to maintain the integrity of connective tissue. A mutation in this gene can affect multiple organ systems, but it is not classically associated with gastrointestinal complications. We describe a man with Marfan syndrome with multiple small bowel diverticula leading to small intestinal bacterial overgrowth and recurrent small bowel perforations.
2018: ACG Case Reports Journal
https://www.readbyqxmd.com/read/29372651/gamma-glutamyltransferase-possible-novel-biomarker-in-colon-diverticulosis-a-case-control-study
#19
Constantin Bălăeţ, Bogdan Ioan Coculescu, Gheorghe Manole, Maria Bălăeţ, Gabi Valeriu Dincă
The gamma-glutamyltransferase (GGT) is recognized in medical practice as a useful indicator for the detection of liver lesions, especially those induced by the excessive consumption of alcoholic or cholesterol-associated drinks. The present study, although it includes a very small number of cases diagnosed with colon diverticulosis-diverticulitis associated with polyposis at the same intestinal level, identifies the presence of increased circulating concentrations of this enzyme in the serum. Its serum levels are tracked "dynamically" throughout a year after the diagnosis and start of the therapy...
December 2018: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/29344786/colonoscopy-induced-acute-diverticulitis-myth-or-reality
#20
Emre Gorgun, Ozgen Isik, Ipek Sapci, Erman Aytac, Maher A Abbas, Gokhan Ozuner, James Church, Scott R Steele
BACKGROUND: Colonoscopy in patients with diverticulosis can be technically challenging and limited data exist relating to the risk of post-colonoscopy diverticulitis. Our aim was to evaluate the incidence, management, and outcomes of acute diverticulitis following colonoscopy. METHODS: Study design is retrospective cohort study. Data were gathered by conducting an automated search of the electronic patient database using current procedural terminology and ICD-9 codes...
January 17, 2018: Surgical Endoscopy
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