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https://www.readbyqxmd.com/read/28320200/clinical-and-biological-features-of-interval-colorectal-cancer
#1
Yu Mi Lee, Kyu Chan Huh
Interval colorectal cancer (I-CRC) is defined as a CRC diagnosed within 60 months after a negative colonoscopy, taking into account that 5 years is the "mean sojourn time." It is important to prevent the development of interval cancer. The development of interval colon cancer is associated with female sex, old age, family history of CRC, comorbidities, diverticulosis, and the skill of the endoscopist. During carcinogenesis, sessile serrated adenomas/polyps (SSA/Ps) share many genomic and colonic site characteristics with I-CRCs...
March 21, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28316316/colonic-diverticulosis-and-diverticulitis-in-renal-transplant-recipients-management-and-long-term-outcomes
#2
Ahmet Rencuzogullari, Gokhan Ozuner, Sinan Binboga, Erman Aytac, Venkatesh Krishnamurthi, Emre Gorgun
Data regarding management of colonic diverticulitis in renal transplant recipients (RTRs) are limited. This study aims to identify prevalence, risk factors, and outcomes in RTRs with colonic diverticulosis and diverticulitis. Between January 2004 and December 2013, all patients who underwent kidney transplantation were analyzed. Among all RTSs, patients who had a pretransplant colonoscopic diagnosis of diverticulosis and patients with a proven attack of diverticulitis were included in our analysis. There were 1578 RTRs with a mean age of 50 ± 14 years at the time of transplantation...
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28286566/gastrointestinal-manifestations-of-mitochondrial-disorders-a-systematic-review
#3
REVIEW
Josef Finsterer, Marlies Frank
Mitochondrial disorders (MIDs) due to respiratory-chain defects or nonrespiratory chain defects are usually multisystem conditions [mitochondrial multiorgan disorder syndrome (MIMODS)] affecting the central nervous system (CNS), peripheral nervous system, eyes, ears, endocrine organs, heart, kidneys, bone marrow, lungs, arteries, and also the intestinal tract. Frequent gastrointestinal (GI) manifestations of MIDs include poor appetite, gastroesophageal sphincter dysfunction, constipation, dysphagia, vomiting, gastroparesis, GI pseudo-obstruction, diarrhea, or pancreatitis and hepatopathy...
January 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28270872/symptomatic-diverticular-disease-in-patients-with-severely-reduced-kidney-function-higher-rates-of-complications-and-transfusion-requirement
#4
Ahmed Dirweesh, Afolarin Amodu, Muhammad Khan, Ritika Zijoo, Bushra Ambreen, Mohammad Ibrahim, Muhammad Ijaz, Abdelhameed Nawwar, Kareem Genena, Muhammad Tahir, Naresh Kumar, Vincent A Debari, Sara Wallach
BACKGROUND: The prevalence of diverticulosis is increasing with 5-10% of patients developing diverticulitis and 5-15% developing symptomatic bleeding. Diverticulitis can result in abscess, perforation, fistula, or obstruction. Bleeding has combined morbidity and mortality rates of 10-20%. The purpose of this study was to compare diverticulitis-related complications and transfusion requirements for diverticular bleeding in patients with normal to moderately reduced kidney function (glomerular filtration rate (GFR) ≥ 30 mL/min/1...
February 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28261773/is-surgery-necessary-to-confirm-diagnosis-of-right-sided-diverticulitis-in-spite-of-relevant-clinical-and-radiological-findings
#5
Erkan Yardımcı, Mustafa Hasbahçeci, Ufuk Oğuz İdiz, Musa Atay, Hüseyin Akbulut
BACKGROUND: Diverticulosis of the right colon is an uncommon entity. Aim of the present study was to report outcome in patients with right-sided diverticulitis diagnosed using computed tomography (CT) and treated conservatively. METHODS: Twelve patients with clinical and radiological diagnosis of cecal or right-sided diverticulitis who were treated conservatively between February 2013 and December 2014 were included. Demographic and clinical data were retrospectively analyzed...
January 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28243433/a-rare-case-of-fusobacterium-necrophorum-liver-abscesses
#6
Faris Hannoodi, Hussam Sabbagh, Zain Kulairi, Sarwan Kumar
Liver abscesses are an uncommon disease that can present with vague symptoms. Fusobacterium necrophorum causing liver abscesses is a rare condition and only a few cases have been reported. An 88-year-old female presented to her primary care physician with one week of fevers, night sweats, chills, fatigue and vague right upper quadrant abdominal pain. She denied nausea, vomiting, constipation, diarrhea and unintentional weight loss. A computed tomography scan of the abdomen showed two liver abscesses in the right lobe as well as extensive diverticulosis...
January 11, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28240003/natural-history-of-bleeding-risk-in-colonic-diverticulosis-review
#7
Lior Segev, Gokhan Ozuner
Colonic diverticulosis prevalence is gradually increasing worldwide. 3-15% of the patients with diverticulosis will bleed at some point. The risk for rebleeding after the first episode is substantial but varies in the literature between 13-48%. We analyze risk factors for diverticular bleed and management options for initial and recurrent diverticular bleeding. A review of the literature on this subject is presented.
February 24, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28215517/rifaximin-and-diverticular-disease-position-paper-of-the-italian-society-of-gastroenterology-sige
#8
Rosario Cuomo, Giovanni Barbara, Bruno Annibale
Management of diverticular disease has significantly improved in the last decade. Antibiotic treatment is used for symptom relief and prevention of complications. In Italy, the non-absorbable antibiotic rifaximin is one of the most frequently used drugs, and it is perceived as the reference drug to treat symptomatic diverticular disease. Its non-systemic absorption and high faecal concentrations have oriented rifaximin use to the gastrointestinal tract, where rifaximin exerts eubiotic effects representing an additional value to its antibiotic activity...
February 1, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28211279/diverticulitis-of-the-appendix-as-debut-of-appendicular-cystadenoma-and-carcinoid-tumor
#9
Laura Fernández Gómez-Cruzado, Mikel Prieto Calvo, Christian Pérez González, Jasone Larrea Oleaga
Appendiceal diverticulosis is a rare condition with a frequency of 0.004% to 2.1%, and is sometimes an occasional finding during anatomopathologic study of the surgical specimen. It may be presented acutely as a right lower quadrant pain, similar to acute appendicitis for which differential diagnosis must be carried out, and it is associated with appendicular tumors. We report a case of diverticulitis of the appendix as debut of appendicular cystadenoma and carcinoid tumor with representative iconography, being unusual the association of both diseases and even more its preoperative diagnosis...
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28183049/case-report-of-a-giant-colonic-sigmoid-diverticulum-causing-sigmoid-volvulus
#10
John Alfred Carr
INTRODUCTION: Giant colonic diverticulum is a rare complication of colonic diverticulosis that occurs when a single diverticulum enlarges to over 4cm in diameter. There have been fewer than 200 cases reported worldwide since it was first described in 1946. PRESENTATION OF CASE: The author presents a rare case of a giant colonic diverticulum that presented as a sigmoid volvulus. The patient underwent emergency surgery with resection of the diverticulum and reduction of the volvulus...
January 25, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28152033/no-neuronal-loss-but-alterations-of-the-gdnf-system-in-asymptomatic-diverticulosis
#11
Martina Barrenschee, Thilo Wedel, Christina Lange, Ines Hohmeier, François Cossais, Michael Ebsen, Ilka Vogel, Martina Böttner
BACKGROUND: Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor known to promote the survival and maintenance of neurons not only in the developing but also in the adult enteric nervous system. As diverticular disease (DD) is associated with reduced myenteric neurons, alterations of the GDNF system were studied in asymptomatic diverticulosis (diverticulosis) and DD. METHODS: Morphometric analysis for quantifying myenteric ganglia and neurons were assessed in colonic full-thickness sections of patients with diverticulosis and controls...
2017: PloS One
https://www.readbyqxmd.com/read/28150481/life-style-and-other-risk-factors-for-diverticulitis
#12
Stephan K Böhm, Wolgang Kruis
BACKGROUND: Diverticulosis is a very common condition. Around 20% of the carriers of diverticula are believed to suffer from diverticular disease during their lifetime. This makes diverticular disease one of the clinically and economically most significant diseases in gastroenterology. The etiopathogenesis of diverticulosis and diverticular disease is not well understood. Epidemiological studies allow to define risk factors for the development of diverticulitis and its complications. METHODS: A comprehensive literature search was performed and the current knowledge about risk factors for diverticulitis and associated conditions reviewed...
February 1, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28122319/a-rare-cause-for-hartmann-s-procedure-due-to-biliary-stent-migration-a-case-report
#13
Petros Siaperas, Argyrios Ioannidis, Andreas Skarpas, Argiris Angelopoulos, Ioannis Drikos, Ioannis Karanikas
INTRODUCTION: Biliary stent migration (proximal or distal) occurs in 6% of all cases. The majority of these migrating stents are passing through the intestine, without causing any complications. Usually when a stent migration occurs, endoscopic retrieval is the proper treatment option, except in case of complications when surgical removal is the only treatment option. This report presents a case of a biliary stent which migrated and caused a sigmoid colon perforation. PRESENTATION OF CASE: A 75 years old female patient presented to the emergency department with diffuse abdominal pain, nausea and vomiting...
January 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28121030/the-gut-microbiome-and-the-mechanism-of-surgical-infection
#14
REVIEW
J C Alverdy, S K Hyoju, M Weigerinck, J A Gilbert
BACKGROUND: Since the very early days of surgical practice, surgeons have recognized the importance of considering that intestinal microbes might have a profound influence on recovery from surgical diseases such as appendicitis and peritonitis. Although the pathogenesis of surgical diseases such as cholelithiasis, diverticulosis, peptic ulcer disease and cancer have been viewed as disorders of host biology, they are emerging as diseases highly influenced by their surrounding microbiota...
January 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28115863/correlation-between-obesity-and-metabolic-syndrome-related-factors-and-cecal-intubation-time-during-colonoscopy
#15
Ryo Kawasato, Shinichi Hashimoto, Tomohiro Shirasawa, Atsushi Goto, Takeshi Okamoto, Jun Nishikawa, Isao Sakaida
PURPOSE: To investigate which colonoscopy (CS) cases should be presided over by endoscopists in training, using factors including obesity and metabolic syndrome. PATIENTS AND METHODS: Items investigated were sex, age, body mass index (BMI), waist circumference, hypertension, diabetes, hyperlipidemia, history of abdominal surgery (excluding colectomy), colon diverticulosis, prescription of antithrombotic agents, and quality of bowel preparation. Expert physicians were defined as those with at least 9 years of endoscopy experience; all other physicians were defined as being in training...
2017: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/28079347/the-diagnostic-challenge-of-symptomatic-uncomplicated-diverticular-disease
#16
Cesare Cremon, Lara Bellacosa, Maria R Barbaro, Rosanna F Cogliandro, Vincenzo Stanghellini, Giovanni Barbara
Colonic diverticulosis is a common condition in Western industrialized countries occurring in up to 65% of people over the age of 60 years. Only a minority of these subjects (about 10- 25%) experience symptoms, fulfilling Rome criteria for irritable bowel syndrome (IBS) diagnosis (IBS-like symptoms) in 10 to 66% of cases. Symptomatic uncomplicated diverticular disease (SUDD) is a syndrome characterized by recurrent abdominal symptoms attributed to diverticula in the absence of macroscopically evident alterations other than the presence of diverticula...
January 12, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28065788/western-dietary-pattern-increases-and-prudent-dietary-pattern-decreases-risk-of-incident-diverticulitis-in-a-prospective-cohort%C3%A2-study
#17
Lisa L Strate, Brieze R Keeley, Yin Cao, Kana Wu, Edward L Giovannucci, Andrew T Chan
BACKGROUND & AIMS: Dietary fiber is implicated as a risk factor for diverticulitis. Analyses of dietary patterns may provide information on risk beyond those of individual foods or nutrients. We examined whether major dietary patterns are associated with risk of incident diverticulitis. METHODS: We performed a prospective cohort study of 46,295 men who were free of diverticulitis and known diverticulosis in 1986 (baseline) using data from the Health Professionals Follow-Up Study...
January 5, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28045757/left-colonic-bleeding-secondary-to-inferior-mesenteric-vein-stenosis
#18
Thang Q Le, Donald Romanelli
Lower gastrointestinal bleeding is most commonly associated with diverticulosis, ischemic colitis, vascular ectasia, and anorectal disease and less commonly associated with colonic malignancy. Infrequently, it is associated with mesenteric varices, a rare etiology that is not well documented in the radiology literature. We present a case of a 50-year-old man diagnosed as having intermittent left colonic bleeding from mesenteric varices due to a critical stenosis at the portal vein-inferior mesenteric vein confluence...
January 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28019112/-indications-diagnoses-and-quality-markers-in-upper-and-lower-endoscopies-in-2010-and-2011-at-the-1st-department-of-medicine-semmelweis-university-budapest
#19
Lóránt Gönczi, Zsuzsanna Kürti, Petra Golovics, Zsuzsanna Végh, Barbara Lovász, Andrea Dorkó, Anna Seres, Liza Sümegi, Orsolya Menyhárt, Lajos Kiss, János Papp, Krisztina Gecse, Péter László Lakatos
INTRODUCTION AND AIM: The aim was to assess the incidence of endoscopic findings based on the indication of the procedures in upper/lower endoscopies, and measuring quality indicators of colonoscopies at the 1st Department of Medicine, Semmelweis University, Budapest. METHOD: Data of 2987 patients (male/female:1361/1626, mean age: 60.7 years(y), SD: 16.7y) between 01.01.2010 and 31.12.2011 were analyzed. Both inpatient and outpatient records were collected. RESULTS: Incidence of peptic ulcer disease, esophageal varices, gastric polyps and gastric cancer were 10...
December 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/28008410/non-meckel-s-small-bowel-diverticular-bleeding-two-case-reports-and-a-review-of-the-literature
#20
Gabriel Mansouraty, Daniel Wild
Gastrointestinal bleeding from non-Meckel's small bowel diverticulosis is uncommon. Depending on the diverticulum's location, a patient's presentation can suggest either an upper or lower gastrointestinal source. We present two cases of bleeding from non-Meckel's small bowel diverticula. One patient was managed successfully with endoscopic therapy, and the second required surgical resection after two failed attempts at achieving hemostasis endoscopically.
August 2016: ACG Case Reports Journal
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