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Diverticulosis

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https://www.readbyqxmd.com/read/28815036/bacterial-stimuli-activate-nitric-oxide-colonic-mucosal-production-in-diverticular-disease-protective-effects-of-l-casei-dg%C3%A2-lactobacillus-paracasei-cncm-i-1572
#1
Fabio Turco, Paolo Andreozzi, Ilaria Palumbo, Francesco Paolo Zito, Martina Cargiolli, Walter Fiore, Nicola Gennarelli, Giovanni Domenico De Palma, Giovanni Sarnelli, Rosario Cuomo
BACKGROUND: Micro-inflammation and changes in gut microbiota may play a role in the pathogenesis of diverticular disease (DD). OBJECTIVE: The objective of this article is to evaluate the expression of nitric oxide (NO)-related mediators and S100B in colonic mucosa of patients with DD in an ex vivo model of bacterial infection. METHODS: Intestinal biopsies obtained from patients with diverticulosis, symptomatic uncomplicated diverticular disease (SUDD) and SUDD with previous acute diverticulitis (SUDD+AD) were stimulated with the probiotic L...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28808610/association-between-alcohol-consumption-and-diverticulosis-and-diverticular-bleeding-a-systematic-review-and-meta-analysis
#2
Veeravich Jaruvongvanich, Anawin Sanguankeo, Sikarin Upala
There have been conflicting reports on the association of alcohol use and diverticular disease. We aimed to determine the odds of developing diverticular disease and diverticular bleeding in patients who consumed alcohol on a regular basis compared with those who did not. MEDLINE and PUBMED were searched up until February 2017 on observational trials, which investigated the effect of alcohol use on two outcomes of diverticular disease: diverticulosis and diverticular bleeding. Quantitative estimates (odds ratios [OR] and confidence intervals [CI]) from included studies were pooled by using a random-effects model...
August 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28799428/full-spectrum-endoscopy-fuse-versus-standard-forward-viewing-endoscope-sfv-in-a-high-risk-population
#3
Søren Roepstorff, Sabah Anwar Hadi, Morten Rasmussen
OBJECTIVES: To investigate the diagnostic performance of Full Spectrum Endoscopy (FUSE) compared to a conventional standard forward-viewing endoscope (SFV). The primary outcome was adenoma detection rate (ADR) and mean adenoma detection. Secondary outcome was feasibility of FUSE opposed to SFV. MATERIALS AND METHODS: Consecutive patients participating in the Danish colorectal cancer (CRC) screening programme were prospectively included in the study (n = 205)...
August 11, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28776378/colonic-diverticulosis-and-the-metabolic-syndrome-an-association
#4
Cristina Teixeira, Daniel Trabulo, Suzane Ribeiro, Cláudio Rodrigues Martins, Ana Luísa Alves, Isabelle Cremers, Ana Paula Oliveira
BACKGROUND AND OBJECTIVES: Colonic diverticulosis (CD) is related to advanced age and a lack of dietary fiber. Recently, several studies have shown that metabolic syndrome (MS) is also implicated in the etiopathogenesis of CD. This study aimed to assess the association between MS, obesity and CD. METHODS: This was a prospective study of a one-year duration. The MS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III)...
August 4, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28768296/dietary-pattern-and-colonic-diverticulosis
#5
Antonio Tursi
PURPOSE OF REVIEW: To assess the role of dietary pattern on the occurrence of colonic diverticulosis, diverticular disease and acute diverticulitis. RECENT FINDINGS: High-fiber diet does not prevent diverticulosis occurrence, and results about prevention/treatment of diverticular disease and acute diverticulitis are still conflicting.No association was seen between nut, corn or popcorn consumption and occurrence of diverticulosis, diverticular disease and acute diverticulitis...
September 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28764591/segmental-colectomy-for-bleeding-diverticular-disease-guided-by-the-peep-test
#6
Vijay Naraynsingh, Shamir O Cawich, Dale Hassranah, Feisal Daniel, Ravi Maharaj, Patrick Harnarayan
Many patients with massive lower gastrointestinal (GI) haemorrhage from diverticulosis are subjected to total colectomy when preoperative localisation is unavailable. We dissected colectomy specimens and noted that there was limited retrograde reflux in most of these cases. Therefore, we sought to assess the value of a positive endoluminal erythrocyte presence (PEEP) test (presence of fresh blood in the caecum) to direct segmental colectomies in 14 patients who required emergency operations for massive lower GI haemorrhage...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28756484/distal-esophageal-spasm-with-multiple-esophageal-diverticula-successfully-treated-by-peroral-endoscopic-myotomy
#7
Koji Otani, Shinwa Tanaka, Fumiaki Kawara, Junichi Fujikawa, Akinari Sawada, Risa Uemura, Tetsuya Tanigawa, Toshio Watanabe, Takeshi Azuma, Yasuhiro Fujiwara
Distal esophageal spasm (DES) is a primary esophageal motility disorder. We encountered a rare case of DES accompanied by multiple esophageal diverticula. A 72-year-old woman complained of prolonged dysphagia and chest pain. A barium esophagogram showed multiple esophageal diverticula and significant contraction of the lower esophagus just above the cardia. Esophagogastroduodenoscopy revealed a corkscrew-like appearance, with spiral contractions and diverticula. High-resolution manometry revealed that the integrated relaxation pressure was normal; premature contractions were observed in ≥20% of the swallowing wave; the distal contractile integral was normal...
July 29, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28756358/jejunal-diverticula-with-perforation-in-non-steroidal-anti-inflammatory-drug-user-a-case-report
#8
Shobhit Gupta, Naveen Kumar
INTRODUCTION: Multiple diverticulosis of the jejunum constitutes an uncommon pathology of the small bowel. The disease is often asymptomatic and must be taken into consideration in cases of unexplained malabsorption, anemia, chronic abdominal pain and discomfort. CASE PRESENTAION: We are thereby reporting a 50yr patient on chronic NSAID ingestion presenting to us with acute abdomen. On exploration, there were multiple (14) jejunal diverticuli on both mesenteric and antimesentric border from 10cm to 90cm distal to duedenojejunal junction with a perforation in one of the diverticulum, 80cm distal to the ligament of Treitz...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28747951/esophageal-diverticulosis
#9
Karina Witkiewicz, Janusz Wójcik, Jarosław Pieróg, Norbert Wójcik, Bogumił Maciąg, Tomasz Grodzki
No abstract text is available yet for this article.
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28723285/case-244-systemic-amyloidosis-a-complication-of-waldenstr%C3%A3-m-macroglobulinemia
#10
Maja Hrabak-Paar, Marko Kralik
History A 68-year-old man was admitted to the hospital for work-up because of generalized fatigue, anorexia, chronic diarrhea, and weight loss. Laboratory work-up revealed an erythrocyte sedimentation rate of 58 mm/h (reference range, 3-23 mm/h), a hemoglobin level of 14.1 g/dL (reference range, 13.8-17.5 g/dL), a leukocyte count of 8.1 × 10(9)/L (reference range, [3.4-9.7] × 10(9)/L), a platelet count of 223 × 10(9)/L (reference range, [158-424] × 10(9)/L), an alkaline phosphatase level of 85 U/L (1.42 μkat/L) (normal level, <142 U/L [2...
August 2017: Radiology
https://www.readbyqxmd.com/read/28712196/small-gut-volvulus-a-rare-twist-in-the-setting-of-an-even-rarer-entity-multiple-giant-jejuno-ileal-diverticula
#11
Ayesha Khan, Faheem Khan, Kashif Rafique, Sarwar Khan, Anam Majid, Khalid Khan, Asad Ullah
Small gut volvulus with multiple Jejuno-ileal diverticulosis is an unusual pathology of the small intestine with a scarce number of cases reported so far. It usually goes unnoticed because it is often asymptomatic but complications like diverticulitis, perforation, bleeding or intestinal obstruction can occur in 10-30% of the cases. Mechanical obstruction, if it occurs, can be caused by adhesions or stenosis due to diverticulitis, intussusception at the site of the diverticulum and volvulus of the segment containing the diverticula...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28703111/clinical-and-microbiological-aspects-of-the-use-of-lactobacillus-rhamnosus-pl1-strains-in-proctological-patients-with-symptoms-of-chronic-proctitis
#12
K Borycka-Kiciak, M Strus, P Pietrzak, K Wawiernia, D Mikołajczyk, M Gałęcka, P Heczko, W Tarnowski
Recurrent proctitis and the symptoms associated therewith pose significant clinical problem in proctological patients. The objective of this study was to assess the impact of the probiotic Lactobacillus rhamnosus PL1 strain on the clinical presentation and composition of intestinal microbiota in patients with symptoms of proctitis in the course of hemorrhoidal disease and diverticulosis. Material consisted of 24 patients in whom no complete clinical improvement could be obtained after the treatment of the underlying disease...
June 30, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28683025/visceral-pain-as-a-triggering-factor-for-fibromyalgia-symptoms-in-comorbid-patients
#13
Raffaele Costantini, Giannapia Affaitati, Ursula Wesselmann, Peter Czakanski, Maria Adele Giamberardino
Fibromyalgia syndrome (FMS) is a central sensitization syndrome; however, peripheral pain sources potentially exacerbate its symptoms of chronic diffuse musculoskeletal pain and hyperalgesia. This prospective study evaluated visceral pain as a possible triggering factor for FMS pain and hyperalgesia in comorbid patients. Women with (1) FMS + irritable bowel syndrome (IBS); (2) FMS + primary dysmenorrhea (Dys); (3) FMS + Dys secondary to endometriosis (Endo); (4) FMS + colon diverticulosis (Div) were compared with FMS-only women, for fibromyalgia pain (number and intensity of episodes and analgesic consumption) over comparable periods and for somatic hyperalgesia (electrical and pressure pain thresholds) in painful (tender points) and control areas (trapezius, deltoid, quadriceps muscles, and overlying subcutis and skin)...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28667725/right-atrial-diverticulosis-and-early-onset-arrhythmia-rare-cause-of-incessant-neonatal-arrhythmia
#14
Neeraj Aggarwal, Raja Joshi, Reena K Joshi, Mridul Agarwal
BACKGROUND: Atrial flutter not responding to medications could be secondary to structural malformations of heart. CASE CHARACTERISTICS: A 5-year-old child with resistant arrhythmia, with onset in neonatal period. OBSERVATIONS: Multiple right atrial diverticuli were detected on CT angiography and cardiac catheterization. Patient reverted to sinus rhythm following surgical excision of diverticuli. MESSAGE: In cases of intractable supraventricular tachycardia, structural anomalies of atrium should be suspected...
June 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28623877/5-aminosalicylic-acid-agents-for-prevention-of-recurrent-diverticulitis-a-systematic-review-and-meta-analysis
#15
Seigo Urushidani, Akira Kuriyama, Masami Matsumura
BACKGROUND AND AIM: Prevalence of colonic diverticulosis is increasing worldwide with age, and up to 25% of patients who have colonic diverticulosis might experience diverticulitis. However, a definitive approach of preventing recurrent diverticulitis remains unknown. 5-aminosalicylic acid (5-ASA) agents are anti-inflammatory agents and have been used to prevent recurrent diverticulitis, and there have been some randomized, clinical trials (RCTs). However, the efficacy results for secondary prevention in uncomplicated diverticulitis differed across studies...
June 17, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28619727/rna-seq-implicates-deregulation-of-the-immune-system-in-the-pathogenesis-of-diverticulitis
#16
Kathleen M Schieffer, Christine S Choi, Scott Emrich, Leonard Harris, Sue Deiling, Dipti M Karamchandani, Anna Salzberg, Yuka I Kawasawa, Gregory S Yochum, Walter A Koltun
Individuals with diverticula or outpouchings of the colonic mucosa and submucosa through the colonic wall have diverticulosis, which is usually asymptomatic. In 10-25% of individuals, the diverticula become inflamed, resulting in diverticulitis. Very little is known about the pathophysiology or gene regulatory pathways involved in the development of diverticulitis. To identify these pathways, we deep sequenced RNAs isolated from full-thickness sections of sigmoid colon from diverticulitis patients and control individuals...
June 15, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28603053/colonic-diverticula-are-not-associated-with-mucosal-inflammation-or-chronic-gastrointestinal-symptoms
#17
Anne F Peery, Temitope O Keku, Cassandra Addamo, Amber N McCoy, Christopher F Martin, Joseph A Galanko, Robert S Sandler
BACKGROUND & AIMS: Colonic diverticulosis has been reported to be associated with low-grade mucosal inflammation, possibly leading to chronic gastrointestinal symptoms. However, there is poor evidence for this association. We aimed to determine whether colonic diverticula are associated with mucosal inflammation and whether diverticula are associated with chronic gastrointestinal symptoms. We explored whether inflammation was present among symptomatic participants with and without diverticula...
June 8, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28597674/diverticulitis-of-the-cecal-appendix-a-case-report
#18
Marta Alberich, Carla Bettonica, Mario Huete, Juan Azcarate
Appendicular diverticulosis is a rare condition. It is important to know its insidious form of presentation for its early diagnosis and treatment, thus diminishing morbimortality. In case of incidental findings, an appendicectomy will be performed to prevent complications and the development of malignancy.
June 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28583217/denis-burkitt-and-the-origins-of-the-dietary-fibre-hypothesis
#19
John H Cummings, Amanda Engineer
For more than 200 years the fibre in plant foods has been known by animal nutritionists to have significant effects on digestion. Its role in human nutrition began to be investigated towards the end of the 19th century. However, between 1966 and 1972, Denis Burkitt, a surgeon who had recently returned from Africa, brought together ideas from a range of disciplines together with observations from his own experience to propose a radical view of the role of fibre in human health. Burkitt came late to the fibre story but built on the work of three physicians (Peter Cleave, G...
June 6, 2017: Nutrition Research Reviews
https://www.readbyqxmd.com/read/28556447/tobacco-smoking-and-the-risk-of-diverticular-disease-a-systematic-review-and-meta-analysis-of-prospective-studies
#20
REVIEW
D Aune, A Sen, M F Leitzmann, S Tonstad, T Norat, L J Vatten
AIM: This systematic review and meta-analysis aimed to clarify whether tobacco smoking is associated with an increased risk of diverticular disease. METHOD: The PubMed and Embase databases were searched for studies of smoking and diverticular disease up to 19 February 2016. Prospective studies that reported adjusted relative risk (RR) estimates and 95% confidence intervals (CIs) of diverticular disease associated with current or previous smoking were included. Summary RRs were estimated using a random effects model...
July 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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