keyword
MENU ▼
Read by QxMD icon Read
search

Neurocysticercosis burden

keyword
https://www.readbyqxmd.com/read/28821422/adhesion-molecules-chemokines-and-matrix-metallo-proteinases-response-after-albendazole-and-albendazole-plus-steroid-therapy-in-swine-neurocysticercosis
#1
Satyendra K Singh, Kashi N Prasad, Aloukick K Singh, Kamlesh K Gupta, Amrita Singh, Mukesh Tripathi, Rakesh K Gupta
The treatment of neurocysticercosis (NCC) varies with location, number and stage of the Taenia solium cysticerci (cysts). Albendazole (ABZ) effectively kills cysticerci, and subsequently induces neuro-inflammation facilitated by leukocyte infiltration. We hypothesize that immune response varies around drug responder (degenerating/dying) and non-responder (viable) cysts after ABZ and ABZ plus steroid (ABZS) therapy, which may determine the disease pathogenesis. Twenty cysticercotic swine were treated with ABZ (n = 10; group1) and ABZS (n = 10; group2)...
August 15, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28658758/a-stratified-analysis-of-clinical-manifestations-and-different-diagnostic-methods-of-neurocysticercosis-suspected-tamilian-population-residing-in-and-around-puducherry
#2
Piriyatharisini Thamilselvan, Krishna Raja Muthuraman, Sheeba Arockiamary Thasan, Gayathri Kasinathan, Jharna Mandal, Subhash Chandra Parija
INTRODUCTION: Human beings are accidental hosts for Cysticercus cellulosae showing varied clinical manifestations based on the site harbored by the parasitic cyst because of which disease profile remains unexplored at large. Besides this, diagnosis of the disease with a single conventional method is problematic due to lack of specificity and sensitivity. AIM: To assess the varied clinical manifestations and stratify based on imaging and serological methods for diagnosis of Neurocysticercosis (NCC) in our study population...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28615981/human-taeniasis-current-insights-into-prevention-and-management-strategies-in-endemic-countries
#3
REVIEW
Anna L Okello, Lian Francesca Thomas
Human taeniasis is a zoonotic condition resulting from infection with the adult stages of Taenia saginata ("beef tapeworm"), Taenia solium ("pork tapeworm") or Taenia asiatica ("Asian tapeworm"). Although these parasites have a worldwide distribution, the overwhelming burden is felt by communities in low- and middle-income countries. This is particularly true for T. solium, whereby infection of the central nervous system with the larval stage of the parasite (neurocysticercosis) is a major cause of acquired epilepsy in low-resource settings...
2017: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/28552103/needs-of-exploring-the-burden-of-recent-onset-seizures-due-to-neurocysticercosis-and-challenges-in-southeast-asia-focusing-on-scenario-in-malaysia
#4
REVIEW
Priyadarshi S Sahu, Yvonne A L Lim, Rohela Mahmud, Sushela D Somanath, Chong T Tan, C P Ramachandran
Seizures due to neurocysticercosis (NCC) is a neglected human-to-human transmitted disorder and an emerging problem worldwide. A substantial portion of recent onset seizures is known to be attributed to NCC in Taenia solium (T. solium) endemic areas where populations which neither raise pigs nor eat pig meat are also at risk. High prevalence of NCC causing epilepsy has been reported in the underdeveloped areas of Southeast Asia (SEA) however, only fragmentary information on its incidence is available in countries like Malaysia...
April 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28376856/the-causal-relationship-between-neurocysticercosis-infection-and-the-development-of-epilepsy-a-systematic-review
#5
REVIEW
Lucy B Gripper, Susan C Welburn
BACKGROUND: Neurocysticercosis (NCC) is a parasitic infection of the human central nervous system, the most common form of which involves infection of the brain parenchyma with the larval form of the Taenia solium tapeworm. A causal relationship between such an NCC infection and the development of epilepsy in infected individuals is acknowledged, in part supported by high levels of comorbidity in endemic countries worldwide. METHODS: This study undertook a systematic review and critical analysis of the NCC-epilepsy relationship with the primary objective of quantifying the risk of developing epilepsy following NCC infection...
April 5, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28289849/geo-helminthiasis-among-migrants-in-sicily-a-possible-focus-for-re-emerging-neurocysticercosis-in-europe
#6
Ildebrando Patamia, Piermario Nicotra, Davide Amodeo, Loretta Giuliano, Calogero Edoardo Cicero, Alessandra Nicoletti
A dramatic increasing immigration flow was recorded in Europe during the last years. Only in Sicily 120,239 people arrived in 2014. Immigrants may carry neglected tropical diseases endemic in their origin countries. The aim of our study was to evaluate the frequency of geo-helminthiasis, and in particular of intestinal taeniasis, in a sample of migrants hosted in a large asylum seeker centre in the province of Catania. A stool sample was obtained from all the enrolled subjects and a coproparasitological examination was performed...
June 2017: Neurological Sciences
https://www.readbyqxmd.com/read/27986419/epilepsy-in-the-tropics-emerging-etiologies
#7
REVIEW
Jaime Carrizosa Moog, Angelina Kakooza-Mwesige, Chong Tin Tan
Epilepsy is considered by the World Health Organization a public health priority with more than 50 million human beings affected by the disease. More than 80% of persons with epilepsy live in low and middle income countries and most of them in tropical areas. Several emerging, re-emerging and neglected diseases are symptomatic etiologies that jointly contribute to the enormous global burden of epilepsy. Besides the clinical strengths to reduce diagnostic and treatment gaps, other strategies in social, economic, cultural, educational and health policies are needed to prevent and treat appropriately vulnerable and affected persons with epilepsy...
January 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27880878/neurocysticercosis-infection-and-disease-a-review
#8
REVIEW
Lucy B Gripper, Susan C Welburn
Neurocysticercosis (NCC) is the most common parasitic disease of the human central nervous system (CNS), a pleomorphic disease with a diverse array of clinical manifestations. The infection is pleomorphic and dependent on a complex range of interconnecting factors, including number and size of the cysticerci, their stage of development and localisation within the brain with resulting difficulties in accurate diagnosis and staging of the disease. This review examines the factors that contribute to the accurate assessment of NCC distribution and transmission that are critical to achieving robust disease burden calculations...
February 2017: Acta Tropica
https://www.readbyqxmd.com/read/27794094/neurocysticercosis-in-bhutan-a-cross-sectional-study-in-people-with-epilepsy
#9
Kate Brizzi, Sonam Pelden, Tshokey Tshokey, Damber K Nirola, Megan B Diamond, Joshua P Klein, Lhab Tshering, Sonam Deki, Dechen Nidup, Veronica Bruno, Pierre Dorny, Hector Hugo Garcia, Farrah J Mateen
BACKGROUND: We sought to provide an assessment of the burden of neurocysticercosis among people with epilepsy (PWE) in Bhutan and evaluate the yield of various tests for Taenia solium. METHODS: PWE were enrolled at the National Referral Hospital in Thimphu (2014-2015). Serum was tested for anti-Taenia solium IgG using ELISA (Ab-ELISA), enzyme-linked immunoelectrotransfer blot (EITB), and parasite antigen. Results were compared to brain MRI. Participants were categorized as definite neurocysticercosis (MRI and EITB positive), probable neurocysticercosis (MRI or EITB positive), or without neurocysticercosis...
September 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27697089/human-cysticercosis-in-portugal-long-gone-or-still-contemporary
#10
M Vilhena, A G Fonseca, S Dias, J Marques DA Silva, J Torgal
Cysticercosis, a leading cause of acquired epilepsy in developing countries, has been controlled or eradicated in industrialized countries. This paradigm has recently been challenged, with human neurocysticercosis (NCC) being increasingly diagnosed in these countries. In order to assess the NCC burden in Portugal, a retrospective study on NCC hospitalizations (2006-2013) was conducted based on the national database on hospital morbidity: 357 hospitalized cases were detected. NCC was most frequent in the following age groups: 20-64 years (n = 197, 55·2%) >64 years (n = 111, 31·1%), and <20 years (n = 49, 13·7%)...
January 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/27642465/neurocysticercosis-among-patients-with-first-time-seizure-in-northern-namibia
#11
Innocent Lule Segamwenge, Ngalyuka Paul Kioko, Celia Mukulu, Ogunsina Jacob, Wanzira Humphrey, Josephine Augustinus
INTRODUCTION: Neurocysticercosis is a common cause of seizures in low resource countries. There is a paucity of data regarding the extent of this infection in Namibia. There are multiple causes of First-time seizure including electrolyte abnormalities, infections, trauma, drugs, alcohol and many times no apparent cause can be found. We sought to describe the burden of Neurocysticercosis among individuals with a first-time seizure in Namibia. METHODS: We recruited 221 patients with a First-time seizure who presented to the Intermediate Hospital Oshakati between August 2012 and March 2014...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27493081/host-th1-th2-immune-response-to-taenia-solium-cyst-antigens-in-relation-to-cyst-burden-of-neurocysticercosis
#12
J Tharmalingam, A T Prabhakar, P Gangadaran, P Dorny, J Vercruysse, P Geldhof, V Rajshekhar, M Alexander, A Oommen
Neurocysticercosis (NCC), Taenia solium larval infection of the brain, is an important cause of acquired seizures in endemic countries, which relate to number, location and degenerating cysts in the brain. Multicyst infections are common in endemic countries although single-cyst infection prevails in India. Single-cyst infections in an endemic country suggest a role for host immunity limiting the infection. This study examined ex vivo CD4(+) T cells and in vitro Th1 and Th2 cytokine responses to T. solium cyst antigens of peripheral blood mononuclear cells of healthy subjects from endemic and nonendemic regions and of single- and multicyst-infected patients for association with cyst burden of NCC...
October 2016: Parasite Immunology
https://www.readbyqxmd.com/read/27332553/reduced-leukocyte-infiltration-in-absence-of-eosinophils-correlates-with-decreased-tissue-damage-and-disease-susceptibility-in-%C3%AE-dblgata-mice-during-murine-neurocysticercosis
#13
Pramod K Mishra, Qun Li, Luis E Munoz, Chris A Mares, Elizabeth G Morris, Judy M Teale, Astrid E Cardona
Neurocysticercosis (NCC) is one of the most common helminth parasitic diseases of the central nervous system (CNS) and the leading cause of acquired epilepsy worldwide. NCC is caused by the presence of the metacestode larvae of the tapeworm Taenia solium within brain tissues. NCC patients exhibit a long asymptomatic phase followed by a phase of symptoms including increased intra-cranial pressure and seizures. While the asymptomatic phase is attributed to the immunosuppressive capabilities of viable T. solium parasites, release of antigens by dying organisms induce strong immune responses and associated symptoms...
June 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27250121/pulmonary-neuroendocrine-carcinoma-mimicking-neurocysticercosis-a-case-report
#14
John C Lam, Stephen R Robinson, Andrew Schell, Stephen Vaughan
BACKGROUND: Neurocysticercosis occurs when the eggs of the pork tapeworm (Taenia solium) migrate and hatch into larvae within the central nervous system. Neurocysticercosis is the most common cause of seizures in the developing world and is characterized on brain imaging by cysts in different stages of evolution. In Canada, cases of neurocysticercosis are rare and most of these patients acquire the disease outside of Canada. We report the case of a patient with multiple intracranial lesions whose history and diagnostic imaging were consistent with neurocysticercosis...
June 2, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27054160/data-and-the-associated-r-code-used-to-estimate-health-and-economic-burden-of-neurocysticercosis-in-india
#15
B B Singh, M S Khatkar, J P S Gill, N K Dhand
This article contains epidemiological, demographic and other data used for estimating health and economic burden of neurocysticercosis (NCC)-associated active epilepsy in India [1]. Most of the data are embedded in the R-code used for analyses so that the reader is able to replicate the results or adapt the code to their own data. However, data used to conduct sensitivity analyses to evaluate the effect of changing important input values such as prevalence and per capita income on health and economic impact of NCC in India are included in tables...
June 2016: Data in Brief
https://www.readbyqxmd.com/read/26802489/estimation-of-the-health-and-economic-burden-of-neurocysticercosis-in-india
#16
B B Singh, M S Khatkar, J P S Gill, N K Dhand
Taenia solium is an endemic parasite in India which occurs in two forms in humans: cysticercosis (infection of soft tissues) and taeniosis (intestinal infection). Neurocysticercosis (NCC) is the most severe form of cysticercosis in which cysts develop in the central nervous system. This study was conducted to estimate health and economic impact due to human NCC-associated active epilepsy in India. Input data were sourced from published research literature, census data and other official records. Economic losses due to NCC-associated active epilepsy were estimated based on cost of treatment, hospitalisation and severe injury as well as loss of income...
January 2017: Acta Tropica
https://www.readbyqxmd.com/read/26580325/global-research-priorities-for-infections-that-affect-the-nervous-system
#17
REVIEW
Chandy C John, Hélène Carabin, Silvia M Montano, Paul Bangirana, Joseph R Zunt, Phillip K Peterson
Infections that cause significant nervous system morbidity globally include viral (for example, HIV, rabies, Japanese encephalitis virus, herpes simplex virus, varicella zoster virus, cytomegalovirus, dengue virus and chikungunya virus), bacterial (for example, tuberculosis, syphilis, bacterial meningitis and sepsis), fungal (for example, cryptococcal meningitis) and parasitic (for example, malaria, neurocysticercosis, neuroschistosomiasis and soil-transmitted helminths) infections. The neurological, cognitive, behavioural or mental health problems caused by the infections probably affect millions of children and adults in low- and middle-income countries...
November 19, 2015: Nature
https://www.readbyqxmd.com/read/26527895/managing-neurocysticercosis-challenges-and-solutions
#18
REVIEW
Yannick Fogoum Fogang, Abdoul Aziz Savadogo, Massaman Camara, Dènahin Hinnoutondji Toffa, Anna Basse, Adjaratou Djeynabou Sow, Mouhamadou Mansour Ndiaye
Taenia solium neurocysticercosis (NCC) is a major cause of neurological morbidity in the world. Variability in the neuropathology and clinical presentation of NCC often make it difficult to diagnose and manage. Diagnosis of NCC can be challenging especially in endemic and resource-limited countries where laboratory and imaging techniques are often lacking. NCC management can also be challenging as current treatment options are limited and involve symptomatic agents, antiparasitic agents, or surgery. Although antiparasitic treatment probably reduces the number of active lesions and long-term seizure frequency, its efficacy is limited and strategies to improve treatment regimens are warranted...
2015: International Journal of General Medicine
https://www.readbyqxmd.com/read/26519884/neurocysticercosis-in-a-rural-population-with-extensive-pig-production-in-ang%C3%A3-nia-district-tete-province-mozambique
#19
Yunus Amade Assane, Chiara Trevisan, Clara Maria Schutte, Emilia Virginia Noormahomed, Maria Vang Johansen, Pascal Magnussen
Neurocysticercosis (NCC) is an important neurological disease in countries with high prevalence of Taenia solium infection and is emerging as a serious public health and economic problem. The aim of this study was to estimate the prevalence of NCC in Angónia district, Tete province, Mozambique based on: prevalence of human T. solium cysticercosis assessed by antigen Enzyme-linked Immunosorbent Assay (Ag-ELISA) seropositivity, history of epilepsy, and brain computed tomography (CT) scan results. A cross sectional study was conducted between September and November 2007 in Angónia district...
January 2017: Acta Tropica
https://www.readbyqxmd.com/read/26336013/immune-response-to-taenia-solium-cysticerci-after-anti-parasitic-therapy
#20
Aloukick K Singh, Satyendra K Singh, Amrita Singh, Kamlesh K Gupta, Jahanarah Khatoon, Amit Prasad, Ravi P Rai, Rakesh K Gupta, Mukesh Tripathi, Nuzhat Husain, Kashi N Prasad
Albendazole is the drug of choice for Taenia solium infection. Concomitant administration of steroid has been advocated to avoid adverse reactions to albendazole therapy in neurocysticercosis. Some T. solium cysticerci (larvae) respond to albendazole therapy while others do not and the reasons remain unexplained. We hypothesise that the immune response differs between treatment responder and non-responder cysticerci and this may determine the outcome. Twenty swine naturally infected with T. solium were purchased from the market and the infection was confirmed by magnetic resonance imaging...
October 2015: International Journal for Parasitology
keyword
keyword
12933
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"