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https://www.readbyqxmd.com/read/28527268/-seroprevalence-and-risk-factors-of-cysticercosis-in-two-rural-communities-in-anzo%C3%A3-tegui-state-venezuela
#1
Manuel Toquero, Antonio Morocoima, Elizabeth Ferrer
INTRODUCTION: Cysticercosis is caused by Taenia solium cysticerci, which are located mainly in the central nervous system causing neurocysticercosis. In Venezuela, few epidemiological studies on this disease have been conducted. OBJECTIVE: To determine the seroprevalence and risk factors for cysticercosis in two rural communities in Anzoátegui state. MATERIAL AND METHODS: We conducted a survey to collect data on possible risk factors and signs and symptoms of the disease, and we took 182 samples in two communities, Boquerón and Punto Lindo...
April 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28526608/microrna-analysis-of-taenia-crassiceps-cysticerci-under-praziquantel-treatment-and-genome-wide-identification-of-taenia-solium-mirnas
#2
Matías Gastón Pérez, Natalia Macchiaroli, Gabriel Lichtenstein, Gabriela Conti, Sebastián Asurmendi, Diego Humberto Milone, Georgina Stegmayer, Laura Kamenetzky, Marcela Cucher, Mara Cecilia Rosenzvit
MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as important regulators of gene expression and perform critical functions in development and disease. In spite of the increased interest in miRNAs from helminth parasites, no information is available on miRNAs from Taenia solium, the causative agent of cysticercosis, a neglected disease affecting millions of people worldwide. Here we performed a comprehensive analysis of miRNAs from Taenia crassiceps, a laboratory model for T. solium studies, and identified miRNAs in the T...
May 17, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28506245/comparison-of-t24h-his-gst-t24h-and-gst-ts8b2-recombinant-antigens-in-western%C3%A2-blot-elisa-and-multiplex-bead-based-assay-for-diagnosis-of-neurocysticercosis
#3
Ana Hernández-González, John Noh, María Jesús Perteguer, Teresa Gárate, Sukwan Handali
BACKGROUND: Currently, the reference standard assay for the serodiagnosis of neurocysticercosis (NCC) is the lentil lectin-bound glycoproteins/enzyme-linked immunoelectrotransfer blot (LLGP-EITB). The main disadvantage of this technique is the complexity of obtaining and purifying the LLGP extract. This could be solved by replacement with highly specific recombinant antigens from Taenia solium. Based on previous studies, we selected and produced the recombinant Ts8B2 and T24H proteins and applied them to three diagnostic techniques: western blot (WB), enzyme-linked immunosorbent assay (ELISA) and the multiplex bead-based assay (MBA)...
May 15, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28484552/isolated-lumbar-intradural-extra-medullary-spinal-cysticercosis-simulating-tarlov-cyst
#4
Sumit Bansal, Ashish Suri, Mehar Chand Sharma, Aanchal Kakkar
Spinal cysticercosis is a very uncommon manifestation of neurocysticercosis, which is caused by the larvae of Taenia solium. Here, we present a rare case of isolated lumbar intradural extramedullary neurocysticercosis, initially thought to be Tarlov cyst. A 40-year-old man, presented with low backache for 1-year with radiation of pain to right leg for 3 months. The patient was treated successfully with the surgical removal of the cyst, followed by medical treatment. Spinal neurocysticercosis should be considered in the differential diagnosis in high-risk populations, with new symptoms suggestive of a spinal mass lesion...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28467600/recent-advancements-and-new-perspectives-in-animal-models-for-neurocysticercosis-immunopathogenesis
#5
REVIEW
N Arora, S Tripathi, P Kumar, P Mondal, A Mishra, A Prasad
Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human), and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tapeworm). Hence, developing an animal model for T. solium that mimics its natural course of infection is quite challenging. We have reviewed here the animal models frequently used to study immunopathogenesis of cysticercosis and also discussed their usefulness for NCC studies...
May 3, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28450211/sero-prevalence-of-taenia-spp-infections-in-cattle-and-pigs-in-rural-farming-communities-in-free-state-and-gauteng-provinces-south-africa
#6
A M Tsotetsi-Khambule, S Njiro, T C Katsande, O M M Thekisoe, L J S Harrison
The aim of this study was to determine sero-prevalence of bovine and porcine cysticercosis in cattle and pigs in rural farming communities in Free State and Gauteng Provinces, Republic of South Africa. Blood samples were collected for a period of twelve months from live cattle (n=1315; 1159) and pigs (n=436; 240) and the serum extracted and stored before analysis by a monoclonal antibody based (HP10) antigen detection ELISA. Results revealed a generally high sero-prevalence and wide distribution throughout the two provinces with Free State having a higher sero-prevalence in both cattle and pigs (23% and 34%) than Gauteng province (15% and 14%)...
April 24, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28443982/enzyme-linked-immunosorbent-assay-for-diagnosis-of-amphimerus-spp-liver-fluke-infection-in-humans
#7
William Cevallos, Manuel Calvopiña, Victoria Nipáz, Belén Vicente-Santiago, Julio López-Albán, Pedro Fernández-Soto, Ángel Guevara, Antonio Muro
BACKGROUND: Amphimerus spp. is a liver fluke that infects humans and domestic animals. It is highly prevalent in some Ecuadorian communities. Currently, diagnosis is based on the microscopic observation of eggs in faeces, but this has variable sensitivity. More sensitive methods are needed for diagnostic testing. OBJECTIVE: The main objective of this work was to develop an enzyme-linked immunosorbent assay (ELISA) using crude antigens from Amphimerus spp. adult worms to detect anti-Amphimerus IgG in human sera...
May 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28435310/tropical-diseases-of-the-myocardium-a-review
#8
REVIEW
Zoe C Groom, Aristotle D Protopapas, Vasileios Zochios
Cardiovascular diseases are widely distributed throughout the world. Human parasitic infections are ubiquitous. Tropical parasites are increasingly recognized as causes of cardiovascular diseases. In this review, we address the most frequently reported parasites that directly infect the myocardium, including Trypanosoma cruzi, the protozoal causative agent of American trypanosomiasis (Chagas disease), and Taenia solium, the cestode causative agent of taeniasis and cysticercosis. We also discuss tropical endomyocardial fibrosis, trichinellosis and schistosomiasis...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28426664/taenia-solium-cysticercosis-and-taeniosis-achievements-from-the-past-10-years-and-the-way-forward
#9
Hélène Carabin, Andrea S Winkler, Pierre Dorny
No abstract text is available yet for this article.
April 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28423884/integrating-market-chain-assessments-with-zoonoses-risk-analysis-in-two-cross-border-pig-value-chains-in-lao-pdr
#10
Anna Okello, Tassilo Tamino Tiemann, Phouth Inthavong, Boualam Khamlome, Ammaly Phengvilaysouk, Soukanh Keonouchanh, Chattouphone Keokhamphet, Virasack Somoulay, Kate Blaszak, Stuart Blacksell, Walter Okello, John Allen
Lao PDR's recent accession to the World Trade Organization necessitates a greater understanding of the patterns and risk of livestock production in order to better align national policy with the Agreement on the Application of Sanitary and Phytosanitary Measures. This eco-health study describes the integration of market chain and zoonoses risk analyses at two strategic cross border points between Lao PDR, Thailand and Viet Nam. Information gained from smallholder farmer/trader interviews was integrated with serological surveys for pig-associated zoonoses - including hepatitis E virus, Taenia solium and Trichinella - to identify potential linkages between disease risk and pig production and slaughter in low input systems common across the country...
March 25, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28406898/spatial-relationship-between-taenia-solium-tapeworm-carriers-and-necropsy-cyst-burden-in-pigs
#11
Ian W Pray, Viterbo Ayvar, Ricardo Gamboa, Claudio Muro, Luz M Moyano, Victor Benavides, Robert H Flecker, Hector H Garcia, Seth E O'Neal
BACKGROUND: Taenia solium, a parasite that affects humans and pigs, is the leading cause of preventable epilepsy in the developing world. Geographic hotspots of pigs testing positive for serologic markers of T. solium exposure have been observed surrounding the locations of human tapeworm carriers. This clustered pattern of seropositivity in endemic areas formed the basis for geographically targeted control interventions, which have been effective at reducing transmission. In this study, we further explore the spatial relationship between human tapeworm carriers and infected pigs using necroscopic examination as a quantitative gold-standard diagnostic to detect viable T...
April 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28386968/water-lily-in-a-subcutaneous-plane-preventing-complications-of-unplanned-excision
#12
Chandraiah Madura, Chaithra Shenoy, Malavalli Lakshminarasimhaiha Girish, Byalakere Shivanna Chandrashekar
Human cysticercosis is caused by the larval form of Taenia solium (T. solium) and is a condition more commonly seen in tropical countries. The infestation can present with varied symptoms depending upon the site of infection, e.g. intramuscular, subcutaneous, intracerebral, or elsewhere. Diagnosing cysticercosis, although fairly easy, becomes challenging in unusual cases. Unplanned excisions can lead to catastrophic complications.
April 7, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28376856/the-causal-relationship-between-neurocysticercosis-infection-and-the-development-of-epilepsy-a-systematic-review
#13
REVIEW
Lucy B Gripper, Susan C Welburn
BACKGROUND: Neurocysticercosis (NCC) is a parasitic infection of the human central nervous system, the most common form of which involves infection of the brain parenchyma with the larval form of the Taenia solium tapeworm. A causal relationship between such an NCC infection and the development of epilepsy in infected individuals is acknowledged, in part supported by high levels of comorbidity in endemic countries worldwide. METHODS: This study undertook a systematic review and critical analysis of the NCC-epilepsy relationship with the primary objective of quantifying the risk of developing epilepsy following NCC infection...
April 5, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28368546/natural-history-of-patients-with-perilesional-edema-around-taenia-solium-calcified-granulomas
#14
Theodore E Nash, JeanAnne M Ware, Siddhartha Mahanty
Background: The transient development of perilesional edema (PE) around ≥1 calcification (defined as 1 episode) occurs in about 50% of the patients with recurrent seizures in calcified neurocysticercosis (NCC). We determined the long-term clinical and radiological course of persons undergoing PE episodes. Methods: Twenty-one persons with NCC who experienced ≥1 PE episode were followed for a median of 10.6 years (range, 0.4-29.2 years). Clinical evaluations and magnetic resonance imaging (MRI) were performed at the time of suggestive symptoms and during routine follow-up...
April 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28359828/tspka-r-a-potential-immunodiagnostic-antigen-for-the-detection-of-porcine-cysticercosis
#15
Guangxue Liu, Panhong Liang, Shaohua Zhang, Aijiang Guo, Lijie Wang, Yadong Zheng, Xuenong Luo
Cysticercosis, caused by metacestodes of Taenia solium, has a significant soci-economic impact and is of considerable importance in public health. However, there are no specific diagnostic antigens to distinguish between T. solim and Taenia hydatigena. In the present study, cAMP-dependent protein kinase regulatory subunit (TsPKA-r), an excretory/secretary (ES) antigen of T. solium, was used to establish a specific and sensitive diagnostic tool for detection of porcine cysticercosis. The full-length sequence encoding TsPKA-r was amplified by PCR, sequenced and then identified by bioinformatics...
March 28, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28336269/epidemiology-of-polyparasitism-with-taenia-solium-schistosomes-and-soil-transmitted-helminths-in-the-co-endemic-village-of-malanga-democratic-republic-of-congo
#16
Joule Madinga, Katja Polman, Kirezi Kanobana, Lisette van Lieshout, Eric Brienen, Nicolas Praet, Constantin Kabwe, Sarah Gabriël, Pierre Dorny, Pascal Lutumba, Niko Speybroeck
Helminth co-infections are common in sub-Saharan Africa. However, little is known about the distribution and determinants of co-infections with Taenia solium taeniasis/cysticercosis. Building on a previous community-based study on human cysticercosis in Malanga village, we investigated co-infections with Taenia solium, soil-transmitted helminths (STHs) and Schistosoma spp and associated risk factors in a random subsample of 330 participants. Real time PCR assays were used to detect DNA of soil-transmitted helminths (STHs), T...
March 20, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28327829/-western-blot-diagnostic-yield-for-simultaneous-antibody-detection-in-patients-with-human-cysticercosis-hydatidosis-and-human-fascioliasis
#17
Kelly Davelois, Hermes Escalante, César Jara
. To determine the diagnostic yield using western blotting to simultaneously detect antibodies in patients with human cysticercosis, hydatidosis, and human fascioliasis. Materials and methods . Cross-sectional study of diagnostic yield assessment. Excretory/secretory antigens were obtained from Taenia solium larvae, Echinococcus granulosus cysts, and the adult flukes of Fasciola hepática, which were then separated using the polyacrylamide gel electrophoresis technique, transferred, and attached to a nitrocellulose membrane to be probed with sera from the patient infected with the three parasites...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28327688/taenia-solium-sneezed-out-from-nose-by-an-asymptomatic-child
#18
N D Pant, M Sharma, S Neupane
Taenia solium is an intestinal parasite and may be excreted in feces in infected patients but our case is unique, as an asymptomatic child sneezed out the proglottids of the parasite from his nose. After the full course of antihelminthic drug the patient excreted a whole worm in his stool.
September 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28322765/hair-cortisol-and-dehydroepiandrosterone-concentrations-in-naturally-taenia-solium-infected-pigs-in-tanzania
#19
COMPARATIVE STUDY
Chiara Trevisan, Marta Montillo, Alberto Prandi, Ernatus M Mkupasi, Helena A Ngowi, Maria V Johansen
The aim of this study was to measure hair cortisol and dehydroepiandrosterone (DHEA) concentrations in naturally Taenia solium infected and non-infected control pigs and assess the effect of an environmental change on the aforementioned parameters. Three hair patches were obtained from 13 T. solium infected and 15 non-infected controls sows, respectively corresponding to 3 time points (prior to, at and approximately two weeks after arrival at the research facility). Cortisol and DHEA were extracted using methanol and analysed by radio immune assay...
May 15, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28320455/a-systematic-review-of-taeniasis-cysticercosis-and-trichinellosis-in-vietnam
#20
REVIEW
Dinh Ng-Nguyen, Mark A Stevenson, Rebecca J Traub
Taeniasis, cysticercosis and trichinellosis have been ranked as the most important food-borne parasites of humans in terms of public health, socioeconomic and trade impact. Despite this, information on these food-borne zoonoses in Vietnam is scarce and fragmented, and many local reports remain inaccessible to the international research community. This study aims to conduct comprehensive literature searches to report on the incidence and estimate the true prevalence of taeniasis in humans and T. solium cysticercosis in humans and pigs in Vietnam utilizing Bayesian models; in addition, to report the incidence and the distribution of trichinellosis...
March 21, 2017: Parasites & Vectors
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