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https://www.readbyqxmd.com/read/29043944/courting-apocalypse-creating-a-zombie-themed-evidence-based-medicine-game
#1
Amy E Blevins, Elizabeth Kiscaden, Jason Bengtson
In 2015, two librarians at the Hardin Library for the Health Sciences at the University of Iowa turned their dreams into a reality and secured funding to build a zombie-themed evidence-based medicine game. The game features a "choose your own adventure" style that takes students through a scenario where a disease outbreak is taking place and a resident is asked to use evidence-based medicine skills to select a screening and diagnostic tool to use on potentially infected patients. Feedback on the game has been positive, and future plans include building additional modules on therapy, harm, and prognosis...
October 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29031310/in-a-bad-place-carers-of-patients-with-head-and-neck-cancer-experiences-of-travelling-for-cancer-treatment
#2
Myles Balfe, Kieran Keohane, Katie O' Brien, Rachael Gooberman-Hill, Rebecca Maguire, Paul Hanly, Eleanor O' Sullivan, Linda Sharp
PURPOSE: To explore the effect that treatment-related commuting has on carers of patients with head and neck cancer. METHOD: Semi-structured interviews, thematically analysed, with 31 carers. RESULTS: Treatment-related commuting had a considerable impact on carers of patients with head and neck cancer, both in practical terms (economic costs, disruption) and also in psychological terms. Many carers of patients with head and neck cancer described becoming distressed by their commute...
October 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/29021246/zombie-reviews-taking-over-the-prospero-systematic-review-registry-it-s-time-to-fight-back
#3
EDITORIAL
Renato Andrade, Rogério Pereira, Adam Weir, Clare L Ardern, João Espregueira-Mendes
No abstract text is available yet for this article.
October 11, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28991606/zombie-issues-in-ophthalmology
#4
EDITORIAL
Nick Mamalis
No abstract text is available yet for this article.
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28610553/zombie-projects-negative-networks-and-multigenerational-science-the-temporality-of-the-international-map-of-the-world
#5
William Rankin
The International Map of the World was a hugely ambitious scheme to create standardized maps of the entire world. It was first proposed in 1891 and remained a going concern until 1986. Over the course of the project's official life, nearly every country in the world took part, and map sheets were published showing all but a few areas of the planet. But the project ended quite unceremoniously, repudiated by cartographers and mapping institutions alike, and it is now remembered as a 'sad story' of network failure...
June 2017: Social Studies of Science
https://www.readbyqxmd.com/read/28606127/augmentation-of-the-anticancer-activity-of-cyt997-in-human-prostate-cancer-by-inhibiting-src-activity
#6
Yong Teng, Yafei Cai, Wenhu Pi, Lixia Gao, Chloe Shay
BACKGROUND: Abnormalities of tubulin polymerization and microtubule assembly are often seen in cancer, which make them very suitable targets for the development of therapeutic approach against rapidly dividing and aggressive cancer cells. CYT997 is a novel microtubule-disrupting agent with anticancer activity in multiple cancer types including prostate cancer. However, the molecular mechanisms of action of CYT997 in prostate cancer have not been well characterized. METHODS: Src knockdown cells were achieved by lentiviral-mediated interference...
June 12, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28539682/the-human-body-as-an-energetic-hybrid-new-perspectives-for-chronic-disease-treatment
#7
REVIEW
Michał Gajewski, Przemysław Rzodkiewicz, Sławomir Maśliński
Inflammatory response is accompanied by changes in cellular energy metabolism. Proinflammatory mediators like plasma C-reactive protein, IL-6, plasminogen activator inhibitor-1, TNF-α or monocyte chemoattractant protein-1 released in the site of inflammation activates immune cells and increase energy consumption. Increased demand for energy creates local hypoxia and lead in consequence to mitochondrial dysfunction. Metabolism of cells is switched to anaerobic glycolysis. Mitochondria continuously generate free radicals that what result in imbalance that causes oxidative stress, which results in oxidative damage...
2017: Reumatologia
https://www.readbyqxmd.com/read/28535871/zombie-soldier-beetles-epizootics-in-the-goldenrod-soldier-beetle-chauliognathus-pensylvanicus-coleoptera-cantharidae-caused-by-eryniopsis-lampyridarum-entomophthoromycotina-entomophthoraceae
#8
Donald C Steinkraus, Ann E Hajek, Jim K Liebherr
Adult goldenrod soldier beetles, Chauliognathus pensylvanicus, were found infected by the fungus Eryniopsis lampyridarum (Entomophthoromycotina) in Arkansas during September - October (1996, 2001, 2015 and 2016). Living and dead infected beetles were found on flowering frost aster, Symphyotrichum pilosum, common boneset, Eupatorium perfoliatum, and Canada goldenrod, Solidago canadensis. Live and dead beetles (n=446) were collected in 1996 from S. pilosum flowers and held individually in the laboratory for determination of fungal prevalence...
September 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28408592/tb-exploits-zombie-cells
#9
Stella M Hurtley
No abstract text is available yet for this article.
April 14, 2017: Science
https://www.readbyqxmd.com/read/28408493/bio-zombie-the-rise-of-pseudoenzymes-in-biology
#10
REVIEW
James M Murphy, Hesso Farhan, Patrick A Eyers
Pseudoenzymes are catalytically dead counterparts of enzymes. Despite their first description some 50 years ago, the importance and functional diversity of these 'fit-for-purpose' polypeptides is only now being appreciated. Pseudoenzymes have been identified throughout all the kingdoms of life and, owing to predicted deficits in enzyme activity due to the absence of catalytic residues, have been variously referred to as pseudoenzymes, non-enzymes, dead enzymes, prozymes or 'zombie' proteins. An important goal of the recent Biochemical Society Pseudoenzymes-focused meeting was to explore the functional and evolutionary diversity of pseudoenzymes and to begin to evaluate their functions in biology, including cell signalling and metabolism...
April 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28376445/are-we-the-walking-dead-burnout-as-zombie-apocalypse
#11
Benjamin R Doolittle
The Walking Dead, one of the most popular television shows in recent history, uses the plot of a zombie apocalypse as a lens into exploring the human condition. Amidst a particularly dangerous moment, the show's hero references the human struggle to survive by remarking, "We are the walking dead." This offhand comment sheds light upon physicians' struggles in medicine, in particular the high prevalence of burnout and the challenge to cultivate compassion and meaning. This is an important question for our age and for our profession...
November 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/28374170/invitromatics-invitrome-and-invitroomics-introduction-of-three-new-terms-for-in-vitro-biology-and-illustration-of-their-use-with-the-cell-lines-from-rainbow-trout
#12
REVIEW
Niels C Bols, Phuc H Pham, Vivian R Dayeh, Lucy E J Lee
The literature on cell lines that have been developed from rainbow trout (RT) (Oncorhynchus mykiss) is reviewed to illustrate three new terms: invitromatics, invitrome, and invitroomics. Invitromatics is defined as the history, development, characterization, engineering, storage, and sharing of cell lines. RT invitromatics differs from invitromatics for humans and other mammals in several ways. Nearly all the RT cell lines have developed through spontaneous immortalization. No RT cell line undergoes senescence and can be described as being finite, whereas many human cell lines undergo senescence and are finite...
April 3, 2017: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28300125/-zombie-patent-fights-over-mutant-mice-return
#13
Heidi Ledford
No abstract text is available yet for this article.
March 15, 2017: Nature
https://www.readbyqxmd.com/read/28148842/real-life-zombie-apocalypse-in-new-york-city
#14
J Mark Brown
Synthetic cannabinoid use elicits "zombie-like" symptoms in New York.
February 1, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28033647/a-new-method-for-evaluating-stallion-sperm-viability-and-mitochondrial-membrane-potential-in-fixed-semen-samples
#15
F J Peña, B A Ball, E L Squires
Multiparametric assessment of stallion sperm quality using flow cytometry can be a useful adjunct in semen evaluation; however, the availability of flow cytometers in veterinary practice is limited. The ability to preserve and transport sperm samples for later flow cytometric analysis using fixable probes would potentially facilitate this process. In the current study, we validated the combination of live/dead Zombie Green(®) (a fixable dye used to assess live and dead sperm) and MitoTracker Deep Red(®) (used to assess mitochondrial membrane potential)...
December 29, 2016: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/27973993/-zombie-outbreak-caused-by-the-synthetic-cannabinoid-amb-fubinaca-in-new-york
#16
Axel J Adams, Samuel D Banister, Lisandro Irizarry, Jordan Trecki, Michael Schwartz, Roy Gerona
BACKGROUND: New psychoactive substances constitute a growing and dynamic class of abused drugs in the United States. On July 12, 2016, a synthetic cannabinoid caused mass intoxication of 33 persons in one New York City neighborhood, in an event described in the popular press as a "zombie" outbreak because of the appearance of the intoxicated persons. METHODS: We obtained and tested serum, whole blood, and urine samples from 8 patients among the 18 who were transported to local hospitals; we also tested a sample of the herbal "incense" product "AK-47 24 Karat Gold," which was implicated in the outbreak...
January 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/27885639/cosmopolitanism-and-the-relevance-of-zombie-concepts-the-case-of-anomic-suicide-amongst-alevi-kurd-youth
#17
Umit Cetin
Against Beck's claims that conventional sociological concepts and categories are zombie categories, this paper argues that Durkheim's theoretical framework in which suicide is a symptom of an anomic state of society can help us understand the diversity of trajectories that transnational migrants follow and that shape their suicide rates within a cosmopolitan society. Drawing on ethnographic data collected on eight suicides and three attempted suicide cases of second-generation male Alevi Kurdish migrants living in London, this article explains the impact of segmented assimilation/adaptation trajectories on the incidence of suicide and how their membership of a 'new rainbow underclass', as a manifestation of cosmopolitan society, is itself an anomic social position with a lack of integration and regulation...
November 25, 2016: British Journal of Sociology
https://www.readbyqxmd.com/read/27877000/psychiatric-aspects-of-toxoplasmosis-an-indian-perspective
#18
Ajish G Mangot
Toxoplasma gondii is one of the well-studied parasites because of its medical and veterinary importance, and its suitability as a model for cell biology and molecular studies. Latent toxoplasmosis in an immunocompetent host was considered benign until recently. The importance of this parasite has been steadily rising in the field of psychiatry and neurology as it has been implicated in numerous neuropsychiatric disorders. Researchers in India have unfortunately restricted themselves to finding the prevalence of toxoplasma antibodies in special populations and animals...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27837014/concerns-with-entertainment-education-zombie-pandemic-preparedness-and-the-unanticipated-promotion-of-a-weapons-culture
#19
Frank Houghton, Jeremy Toms, Ghazal Meratnia, Krista Loney, Edward Hopkins, Katie Del Monte
Entertainment-education has proved to be an engaging medium through which to explore health and social issues in populations. Given the popularity of the zombie theme in popular culture it is no surprise therefore that the Centers for Disease Control and Prevention adopted this theme in an effort to engage youth and young adults in emergency preparedness. However, an earlier observational study involving elementary school children based on this premise raised concerns that it may have unexpectedly promoted a focus on firearms...
August 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/27835992/the-evolving-world-of-pseudoenzymes-proteins-prejudice-and-zombies
#20
Patrick A Eyers, James M Murphy
Pseudoenzymes are catalytically deficient variants of enzymes that are represented in all major enzyme families. Their regulatory functions in signalling pathways are shedding new light on the non-catalytic functions of active enzymes, and are suggesting new ways to target cellular signalling mechanisms with drugs.
November 11, 2016: BMC Biology
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