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https://www.readbyqxmd.com/read/29049932/determinants-of-comorbid-depression-and-anxiety-postnatally-a-longitudinal-cohort-study-of-chinese-canadian-women
#1
Cindy-Lee Dennis, Hilary K Brown, Susitha Wanigaratne, Simone N Vigod, Sophie Grigoriadis, Kenneth Fung, Flavia Marini, Sarah Brennenstuhl
BACKGROUND: Women with comorbid depression and anxiety in the postpartum period experience more complex and severe symptoms than women with depression or anxiety alone; however, little is known about what influences these symptoms, especially among women from specific ethnic backgrounds. The objective of this study was to identify determinants of comorbid depression and anxiety symptomatology by 24 weeks postpartum in a cohort of Chinese-Canadian women. METHODS: A longitudinal cohort study was completed where 549 Chinese immigrant and Canadian-born women in Toronto were followed to 24 weeks postpartum...
September 25, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29048739/pharmacotherapy-for-social-anxiety-disorder-sand
#2
REVIEW
Taryn Williams, Coenraad J Hattingh, Catherine M Kariuki, Sean A Tromp, Anton J van Balkom, Jonathan C Ipser, Dan J Stein
BACKGROUND: Recognition is growing that social anxiety disorder (SAnD) is a chronic and disabling disorder, and data from early trials demonstrate that medication may be effective in its treatment. This systematic review is an update of an earlier review of pharmacotherapy of SAnD. OBJECTIVES: To assess the effects of pharmacotherapy for social anxiety disorder in adults and identify which factors (methodological or clinical) predict response to treatment. SEARCH METHODS: We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR-Studies and CCMDCTR-References) to 17 August 2015...
October 19, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29048300/intensive-family-exposure-based-cognitive-behavioral-treatment-for-adolescents-with-anorexia-nervosa
#3
Marina Iniesta Sepúlveda, Joshua M Nadeau, Megan K Whelan, Christina M Oiler, Amaya Ramos, Bradley C Riemann, Eric A Storch
BACKGROUND: Anorexia nervosa exhibits high comorbidity rates and shared features with anxiety disorders and obsessive-compulsive disorder. Anxiety-based etiological models have proposed that fear of eating-related stimuli is the central mechanism around which avoidance of food and food-related rituals are performed. Building on this approach, exposure-based interventions have demonstrated promising results. Limited evidence in adolescents encourages the evaluation of exposure approaches in this population...
November 2017: Psicothema
https://www.readbyqxmd.com/read/29046179/coping-and-changes-in-arousal-after-exposure-to-gz-load
#4
Marcin Piotr Biernacki, Rafal Lewkowicz, Piotr Zieliński, Mieczyslaw Wojtkowiak
BACKGROUND: Acceleration load causes several physiological changes that play important roles in pilot performance. One of the problems is determining individual factors responsible for the differences in changes in the level of central nervous system (CNS) arousal after exposure to acceleration loads. We were interested in whether the coping style and anxiety as a trait might differentiate the subjects in terms of reactions of the CNS to +Gz load-related stress. METHODS: Examined were 31 male volunteers with ages between 23 and 30 yr...
November 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29045928/factors-associated-with-alcohol-consumption-among-medical-cannabis-patients-with-chronic-pain
#5
Alan K Davis, Maureen A Walton, Kipling M Bohnert, Carrie Bourque, Mark A Ilgen
INTRODUCTION: Chronic pain is the most common reason for medical cannabis certification. Data regarding alcohol use and risky drinking among medical cannabis patients with pain is largely unknown. Therefore, we examined the prevalence and correlates of alcohol use and risky drinking in this population. METHODS: Participants completed surveys regarding demographics, pain-related variables, anxiety, cannabis use, and past six-month alcohol consumption. Alcohol use groups were defined using the AUDIT-C [i...
October 12, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29045745/long-term-oral-appliance-therapy-improves-daytime-function-and-mood-in-upper-airway-resistance-syndrome-patients
#6
Luciana B M Godoy, Luciana Palombini, Dalva Poyares, Cibele Dal-Fabbro, Thaís Moura Guimarães, Priscila Calixto Klichouvicz, Sergio Tufik, Sonia Maria Togeiro
Objectives: To evaluate the long term effects of an oral appliance on clinical symptoms, respiratory sleep parameters, sleep quality and sustained attention in patients with Upper Airway Resistance Syndrome (UARS) compared with placebo. Methods: This study was a randomized placebo-controlled clinical trial. Thirty UARS patients were randomized in two groups: placebo and mandibular advancement device (MAD) groups. UARS criteria were presence of sleepiness (Epworth Sleepiness Scale ≥ 10) and/or fatigue (Modified Fatigue Impact Scale ≥ 38) associated with an apnea/hypopnea index (AHI) ≤ 5 and a respiratory disturbance index (RDI) > 5 events/hour of sleep, and/or flow limitation in more than 30% of total sleep time...
October 17, 2017: Sleep
https://www.readbyqxmd.com/read/29044497/pediatric-headache-and-sleep-disturbance-a-comparison-of-diagnostic-groups
#7
Jonathan Rabner, Karen J Kaczynski, Laura E Simons, Alyssa LeBel
OBJECTIVE: To examine whether sleep disturbance differs by headache diagnosis in a pediatric sample, and whether this effect remains when other factors affecting sleep are included. BACKGROUND: Primary headache disorders can be severe and disabling, impacting a child's functioning and quality of life. Many children and adolescents with chronic headaches also experience sleep difficulties, and there is likely a bidirectional relationship between headaches and sleep difficulties...
October 17, 2017: Headache
https://www.readbyqxmd.com/read/29044007/depressive-symptoms-monoamines-levels-mao-b-activity-and-effect-of-treatment-in-a-subset-of-depressed-individuals-from-government-sector-hospital-at-karachi
#8
Farah Zeb, Sabira Naqvi, Razaur Rahman, Ahsana Dar Farooq
Depression is one of the leading causes of disability in developing countries including Pakistan. This study was designed to assess the frequency and severity of depressive symptoms, monoamines and their metabolite levels, MAO-B activities before and after treatment with antidepressants in a sub-set of Karachi population in Pakistan. Drug naive depressed subjects were evaluated before and after treatment with selective serotonin reuptake inhibitors. Symptoms of depressed mood and anxiety psychic (90%) were more frequent whereas, suicidal thoughts (~50%) and feelings of guilt (~30%) were less common...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29042764/the-association-between-objectively-measured-physical-activity-and-morning-symptoms-in-copd
#9
Amanda R van Buul, Marise J Kasteleyn, Niels H Chavannes, Christian Taube
PURPOSE: The morning is the most bothersome period for COPD patients. Morning symptom severities in different Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages are not well studied. Furthermore, factors that are associated with morning symptoms, especially the associations with objectively measured physical activity, are also not well described. MATERIALS AND METHODS: The aim of this cross-sectional observational study was to assess morning symptom severity in GOLD A, B, C and D patients, according to the definitions of the GOLD 2015 statement...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29042389/what-s-up-doc-a-national-cross-sectional-study-of-psychological-wellbeing-of-hospital-doctors-in-ireland
#10
Blánaid Hayes, Lucia Prihodova, Gillian Walsh, Frank Doyle, Sally Doherty
OBJECTIVES: To measure levels of psychological distress, psychological wellbeing and self-stigma in hospital doctors in Ireland. DESIGN: National cross-sectional study of randomised sample of hospital doctors. Participants provided sociodemographic data (age, sex, marital status), work grade (consultant, higher/basic specialist trainee), specialty and work hours and completed well-being questionnaires (the Depression Anxiety Stress Scale, WHO Well-being Index, General Health Questionnaire) and single-item scales on self-rated health and self-stigma...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29042065/analgesic-and-anxiolytic-effects-of-leu-31-pro-34-neuropeptide-y-microinjected-into-the-periaqueductal-gray-in-rats
#11
Priscila Vázquez-León, Luis G Mendoza-Ruiz, Eduardo Ramírez-San Juan, German Alberto Chamorro-Cevallos, Abraham Miranda-Páez
Several reports have demonstrated that neuropeptide Y (NPY) is involved in food intake, epilepsy, circadian rhythms, drug seeking, pain and anxiety, and other physiological or pathological conditions. On the other hand, periaqueductal gray (PAG) is a key brain center for modulating pain, anxiety and fear. It is the main structure implicated in integrated defensive behaviors. One such behavior, tonic immobility (TI), resembles fear and is able to induce analgesia. After microinjection of [Leu(31),Pro(34)]-Neuropeptide Y ([Leu(31),Pro(34)]-NPY) into the PAG dorsal (D) or ventrolateral (VL) of adult male Wistar rats, the following parameters were assessed: i) the analgesic effect by means of the tail-flick test (TF), ii) the duration of TI as a passive defensive behavioral response and as an anxiety/fear model (considering both TF and TI as single behaviors), iii) TI-induced analgesia by the combination of TF/TI, and iv) the anxious-like state through the elevated plus maze (EPM), and defensive burying behavior (DBB)...
October 12, 2017: Neuropeptides
https://www.readbyqxmd.com/read/29041880/-efficacy-of-antihypertensive-therapy-combined-with-psychotropic-drugs-in-patients-with-hypertension-and-affective-disorders
#12
V V Skibitskiy, V D Kovalev, N A Kurzanov, I A Ponomareva
AIM: To compare effects of isolated antihypertensive therapy (AHT) and AHT combined with anxiolytic and antidepressant on parameters of 24‑hour blood pressure (BP) profile, severity of affective disorders, and quality of life (QL) in patients with uncontrolled arterial hypertension (AH) and anxiety or depressive disorders. MATERIAL AND METHODS: We randomized 140 patients (age 48.6±5.9 year, 72 women) into 2 groups. During 1 year patients of each group received 2 variants of pharmacotherapy: isolated AHT and AHT combined with psychotropic medication (PM) - anxiolytic for persons with anxiety disorder and antidepressant for persons with depressive disorder (AHT+PM)...
July 2017: Kardiologiia
https://www.readbyqxmd.com/read/29040890/omega-3-and-omega-6-fatty-acid-levels-in-depressive-and-anxiety-disorders
#13
Carisha S Thesing, Mariska Bot, Yuri Milaneschi, Erik J Giltay, Brenda W J H Penninx
BACKGROUND: Blood levels of polyunsaturated fatty acids (PUFAs) have been associated to current depression. However, it is unclear whether this association extends to remitted depression and to anxiety disorders. This study examined the relationship of PUFAs with the presence and clinical characteristics of depressive and anxiety disorders. METHODS: Cross-sectional data was used from the Netherlands Study of Depression and Anxiety, including persons with current pure depressive disorder (n=304), current pure anxiety disorder (n=548), current comorbid depressive and anxiety disorder (n=529), remitted depressive/anxiety disorder(s) (n=897), and healthy controls (n=634)...
October 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29040524/potentiation-of-excitatory-synaptic-transmission-ameliorates-aggression-in-mice-with-stxbp1-haploinsufficiency
#14
Hiroyuki Miyamoto, Atsushi Shimohata, Manabu Abe, Teruo Abe, Emi Mazaki, Kenji Amano, Toshimitsu Suzuki, Tetsuya Tatsukawa, Shigeyoshi Itohara, Kenji Sakimura, Kazuhiro Yamakawa
Genetic studies point to a major role of de novo mutations in neurodevelopmental disorders of intellectual disability, autism spectrum disorders, and epileptic encephalopathy. The STXBP1 gene encodes the syntaxin-binding protein 1 (Munc18-1) that critically controls synaptic vesicle exocytosis and synaptic transmission. This gene harbors a high frequency of de novo mutations, which may play roles in these neurodevelopmental disorders. However, the system and behavioral-level pathophysiological changes caused by these genetic defects remain poorly understood...
October 11, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29040021/flexible-sigmoidoscopy-and-ct-colonography-screening-patients-experience-with-and-factors-for-undergoing-screening-insight-from-the-proteus-colon-trial
#15
Carlo Senore, Loredana Correale, Daniele Regge, Cesare Hassan, Gabriella Iussich, Marco Silvani, Arrigo Arrigoni, Lia Morra, Nereo Segnan
Purpose To compare the acceptability of computed tomographic (CT) colonography and flexible sigmoidoscopy (FS) screening and the factors predicting CT colonographic screening participation, targeting participants in a randomized screening trial. Materials and Methods Eligible individuals aged 58 years (n = 1984) living in Turin, Italy, were randomly assigned to be invited to screening for colorectal cancer with FS or CT colonography. After individuals who had died or moved away (n = 28) were excluded, 264 of 976 (27...
October 17, 2017: Radiology
https://www.readbyqxmd.com/read/29039150/anxiety-depression-and-coping-behaviors-with-pain-in-cancer-patients-who-are-aware-or-unaware-of-their-cancer
#16
Gülcan Güleç, Sacit Güleç, Dilek Ceyhan, Muhtelime Bahar, Soner Özdemir
OBJECTIVES: This study aimed to investigate whether there are differences in depression, anxiety, pain and styles of coping with pain between cancer patients with and without awareness of their cancer diagnosis. METHODS: In this study, 30 cancer patients aware of their diagnosis and 30 cancer patients unaware of their diagnosis, all of whom visited a clinic for pain treatment, were enrolled in this study. A sociodemographic information form, a questionnaire comprising questions about pain severity and related variables, Hospital Anxiety Depression Scale, and the Pain Coping Questionnaire were administered to the patients...
July 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29038946/cognitive-and-behavioral-disorders-in-parkinson-s-disease-an-update-ii-behavioral-disorders
#17
Luigi Trojano, Costanza Papagno
Patients with Parkinson's disease (PD) can experience several behavioral symptoms, such as apathy, agitation, hypersexuality, stereotypic movements, pathological gambling, abuse of antiparkinsonian drugs, and REM sleep behavioral disorders. Psychoses and hallucinations, depression and anxiety disorders, and difficulties in recognizing and experiencing emotions also impair behavior and can cause severe psychosocial problems in patients with PD. Symptoms can be present since early stages of the disease, sometimes even before the appearance of classical motor symptoms, likely in relation to dopamine depletion in basal ganglia and/or to dysfunctions of other neurotrasmitter systems, and others can develop later, in some cases in relation to dopaminergic treatment...
October 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29038686/the-assessment-of-psychopathology-among-traumatized-refugees-measurement-invariance-of-the-harvard-trauma-questionnaire-and-the-hopkins-symptom-checklist-25-across-five-linguistic-groups
#18
Tim R Wind, Niels van der Aa, Simone de la Rie, Jeroen Knipscheer
Background: Questionnaires are widely used to assess the mental health status of refugees, whereas their construct validity largely remains unexplored. Objective: This study examined the construct validity of two widely-used instruments for the assessment of PTSD symptoms (Harvard Trauma Questionnaire [HTQ]; 16 items) and symptoms of anxiety and depression (Hopkins Symptom Check list-25 [HSCL-25]; 25 items) among Dutch and refugee patients with different linguistic backgrounds. Method: We applied exploratory factor analyses and measurement invariance analyses to test construct validity...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29037196/unmet-clinical-needs-and-burden-in-angelman-syndrome-a-review-of-the-literature
#19
REVIEW
Anne C Wheeler, Patricia Sacco, Raquel Cabo
BACKGROUND: Angelman syndrome (AS) is a rare disorder with a relatively well-defined phenotype. Despite this, very little is known regarding the unmet clinical needs and burden of this condition, especially with regard to some of the most prevalent clinical features-movement disorders, communication impairments, behavior, and sleep. MAIN TEXT: A targeted literature review using electronic medical databases (e.g., PubMed) was conducted to identify recent studies focused on specific areas of the AS phenotype (motor, communication, behavior, sleep) as well as epidemiology, diagnostic processes, treatment, and burden...
October 16, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29036013/patient-experience-based-value-sets-are-they-stable
#20
A Simon Pickard, Yu-Ting Hung, Fang-Ju Lin, Todd A Lee
BACKGROUND: Although societal preference weights are desirable to inform resource-allocation decision-making, patient experienced health state-based value sets can be useful for clinical decision-making, but context may matter. OBJECTIVE: To estimate EQ-5D value sets using visual analog scale (VAS) ratings for patients undergoing knee replacement surgery and compare the estimates before and after surgery. METHODS: We used the Patient Reported Outcome Measures data collected by the UK National Health Service on patients undergoing knee replacement from 2009 to 2012...
October 13, 2017: Medical Care
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