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https://www.readbyqxmd.com/read/28231011/ultrahigh-responsivity-photodetectors-from-perovskite-nanowire-arrays-for-sequentially-tunable-spectral-measurement
#1
Wei Deng, Liming Huang, Xiuzhen Xu, Xiujuan Zhang, Xiangcheng Jin, Shuit-Tong Lee, Jiansheng Jie
Compared with polycrystalline films, single-crystalline methylammonium lead halide (MAPbX3, X = halogen) perovskite nanowires (NWs) with well-defined structure possess superior optoelectronic properties for optoelectronic applications. However, most of the prepared perovskite NWs exhibit properties below expectations due to poor crystalline quality and rough surfaces. It also remains a challenge to achieve aligned growth of single-crystalline perovskite NWs for integrated device applications. Here, we report a facile fluid-guided anti-solvent vapor-assisted crystallization (FGAVC) method for large-scale fabrication of high-quality single-crystalline MAPb(I1-xBrx)3 (X = 0, 0...
February 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28230594/alveolar-molding-effect-in-infants-with-unilateral-cleft-lip-and-palate-comparison-of-two-and-three-dimensional-measurements
#2
Won Hee Lim, Eun Woo Park, Hwa Sung Chae, Soon Man Kwon, Hoi-In Jung, Seung-Hak Baek
The purpose of this study was to compare the results of two- (2D) and three-dimensional (3D) measurements for the alveolar molding effect in patients with unilateral cleft lip and palate. The sample consisted of 23 unilateral cleft lip and palate infants treated with nasoalveolar molding (NAM) appliance. Dental models were fabricated at initial visit (T0; mean age, 23.5 days after birth) and after alveolar molding therapy (T1; mean duration, 83 days). For 3D measurement, virtual models were constructed using a laser scanner and 3D software...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230406/test-retest-reliability-of-the-facial-expression-labeling-task
#3
Jennifer L Cecilione, Lance M Rappaport, Brad Verhulst, Dever M Carney, R J R Blair, Melissa A Brotman, Ellen Leibenluft, Daniel S Pine, Roxann Roberson-Nay, John M Hettema
Recognizing others' emotional expressions is vital for socioemotional development; impairments in this ability occur in several psychiatric disorders. Further study is needed to map the development of this ability and to evaluate its components as potential transdiagnostic endophenotypes. Before doing so, however, research is required to substantiate the test-retest reliability of scores of the face emotion identification tasks linked to developmental psychopathology. The current study estimated test-retest reliability of scores of one such task, the facial expression labeling task (FELT) among a sample of twin children (N = 157; ages 9-14)...
February 23, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28230260/elevation-of-sharpin-protein-levels-in-prostate-adenocarcinomas-promotes-metastasis-and-impairs-patient-survivals
#4
Hai Huang, Tao Du, Yiming Zhang, Yiming Lai, Kaiwen Li, Xinxing Fan, Dingjun Zhu, Tianxin Lin, Kewei Xu, Jian Huang, Leyuan Liu, Zhenghui Guo
BACKGROUND: SHARPIN, SHANK-associated RH domain interacting protein, associates with a linear ubiquitin chain assembly complex (LUBAC) to regulate inflammation and immunity. It has been reported that SHARPIN is highly expressed in several human tumors including ovarian cancer and liver cancer. We found that SHARPIN is also highly expressed in prostate cancer cell lines of DU145, LNCAP, and PC-3. Suppression of SHARPIN caused an inhibition of NF-κB signal and decreases in tumorigenesis of cultured cells in NOD/SCID mouse model...
February 23, 2017: Prostate
https://www.readbyqxmd.com/read/28229578/growth-and-pubertal-development-in-adolescent-male-wrestlers
#5
İbrahim E Pişkin, Mustafa Gümüş, Taner Bayraktaroğlu, Tevfik C Akalin, Faruk Yamaner
BACKGROUND: Adolescence is a crucial period for linear growth, and sports training during this time may have positive or negative effects on some physiological processes as growth. The purpose of this study was to evaluate the effects of intense training during somatic growth on the onset of puberty and growth development in adolescent wrestlers. METHODS: Fifty adolescent male wrestlers and twenty-one sedentary healthy male controls aged between 13-15 years were selected...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28229260/dehydroepiandrosterone-sulfate-dhea-s-sex-and-age-in-zoo-housed-western-lowland-gorillas-gorilla-gorilla-gorilla
#6
Ashley N Edes
Among humans, dehydroepiandrosterone-sulfate (DHEA-S) declines with age and is hypothesized to be involved in somatic maintenance and healthy aging. Men have significantly higher DHEA-S than women, contradicting longer lifespans in the latter. Declines of DHEA-S with age also are observed in chimpanzees. In both chimpanzees and bonobos, males and females show no differences in DHEA-S production. Based on human and chimpanzee data, gorillas were predicted to show declining DHEA-S with age. Similar to chimpanzees and bonobos, it also was predicted DHEA-S would not be significantly different between males and females...
February 22, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28227835/multi-chip-dataflow-architecture-for-massive-scale-biophysically-accurate-neuron-simulation
#7
Jaco Hofmann, Amir Zjajo, Carlo Galuzzi, Rene van Leuken, Jaco Hofmann, Amir Zjajo, Carlo Galuzzi, Rene van Leuken, Carlo Galuzzi, Rene Van Leuken, Jaco Hofmann, Amir Zjajo
State-of-the-art neuron simulators are capable of simulating at most few tens/hundreds of neurons in real-time due to the exponential growth in the communication costs with the number of simulated neurons. In this paper, we present a novel, reconfigurable, multi-chip system architecture based on localized communication, which effectively reduces the communication cost to a linear growth. The system is very flexible and it allows to tune, at run-time, various parameters, e.g. the intracellular concentration of chemical compounds, the interconnection scheme between the neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226646/comparison-of-data-mining-techniques-applied-to-fetal-heart-rate-parameters-for-the-early-identification-of-iugr-fetuses
#8
G Magenes, R Bellazzi, A Malovini, M G Signorini, G Magenes, R Bellazzi, A Malovini, M G Signorini, R Bellazzi, M G Signorini, G Magenes, A Malovini
The onset of fetal pathologies can be screened during pregnancy by means of Fetal Heart Rate (FHR) monitoring and analysis. Noticeable advances in understanding FHR variations were obtained in the last twenty years, thanks to the introduction of quantitative indices extracted from the FHR signal. This study searches for discriminating Normal and Intra Uterine Growth Restricted (IUGR) fetuses by applying data mining techniques to FHR parameters, obtained from recordings in a population of 122 fetuses (61 healthy and 61 IUGRs), through standard CTG non-stress test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226409/effects-of-xylanase-supplementation-on-growth-performance-nutrient-digestibility-blood-parameters-fecal-microbiota-fecal-score-and-fecal-noxious-gas-emission-of-weaning-pigs-fed-corn-soybean-meal-based-diet
#9
Ruixia Lan, Tianshui Li, Inho Kim
This study was conducted to evaluate the effects of xylanase supplementation on nutrient digestibility, growth performance, blood parameters, fecal microflora shedding, fecal score and fecal noxious gas emission of weaning pigs fed corn-soybean meal based diet. A total of 150 weaning pigs with an average initial body weight (BW) of 7.85 ± 0.93 kg were randomly allocated to three treatments based on BW and sex (10 replicate pens with five pigs, two gilts and three barrows) were used in this 42-day trial...
February 22, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28225306/hydrocortisone-therapy-and-growth-trajectory-in-children-with-classical-congenital-adrenal-hyperplasia
#10
Carla Bizzarri, Nicola Improda, Chiara Maggioli, Donatella Capalbo, Silvia Roma, Ottavia Porzio, Mariacarolina Salerno, Marco Cappa
OBJECTIVE: Poor linear growth is one of the main concerns in children with congenital adrenal hyperplasia (CAH). We aimed to analyze factors affecting growth trajectory in children with classical CAH. METHODS: Clinical records of children followed from infancy up to the end of growth at two Italian tertiary referral hospitals were reviewed. Fifty-seven patients (31 males), treated with hydrocortisone and fludrocortisone only, were included. Clinical observations were divided into 3 groups: 0-2 years: 172 observations; from 2 years to puberty onset: 813 observations; after puberty onset: 527 observations...
February 22, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28224267/selection-of-dna-aptamers-for-extra-cellular-domain-of-human-epidermal-growth-factor-receptor-2-to-detect-her2-positive-carcinomas
#11
A Sett, B B Borthakur, U Bora
BACKGROUND: Human epidermal growth factor receptor 2 (Her2, an orphan receptor of ErbB family) is considered as an important biomarker as it plays a key role in the development and progression of aggressive types of breast, ovarian, stomach and gastric cancer. In the present study, we developed novel DNA aptamers against the extra-cellular domain (ECD) of Her2 protein for detection of Her2-positive carcinomas. METHODS: We cloned and expressed Her2-ECD protein in E...
February 21, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28222325/household-food-group-expenditure-patterns-are-associated-with-child-anthropometry-at-ages-5-8-and-12-years-in-ethiopia-india-peru-and-vietnam
#12
Debbie L Humphries, Kirk A Dearden, Benjamin T Crookston, Tassew Woldehanna, Mary E Penny, Jere R Behrman
: Population-level analysis of dietary influences on nutritional status is challenging in part due to limitations in dietary intake data. Household expenditure surveys, covering recent household expenditures and including key food groups, are routinely conducted in low- and middle-income countries. These data may help identify patterns of food expenditure that relate to child growth. OBJECTIVES: We investigated the relationship between household food expenditures and child growth using factor analysis...
February 14, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28221878/prediction-of-escherichia-coli-o157-h7-salmonella-and-listeria-monocytogenes-growth-in-leafy-greens-without-temperature-control
#13
Abhinav Mishra, Miao Guo, Robert L Buchanan, Donald W Schaffner, Abani K Pradhan
A recent study by the Centers for Disease Control and Prevention reported that between 1998 and 2008, leafy greens outbreaks accounted for 22.3% of foodborne outbreaks in the United States. Several studies on the growth of bacteria at different temperatures have been conducted; however, there is a need for the prediction of bacterial growth when leafy greens are transported without temperature control. Food products, when taken out of refrigeration, undergo a temperature change, with the rate of temperature change being proportional to the difference in the temperature of food and its surroundings...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28221346/synthesis-of-ent-be-43547a1-reveals-a-potent-hypoxia-selective-anticancer-agent-and-uncovers-the-biosynthetic-origin-of-the-apd-cld-natural-products
#14
Nikolaj L Villadsen, Kristian M Jacobsen, Ulrik B Keiding, Esben T Weibel, Bjørn Christiansen, Thomas Vosegaard, Morten Bjerring, Frank Jensen, Mogens Johannsen, Thomas Tørring, Thomas B Poulsen
Tumour hypoxia is speculated to be a key driver of therapeutic resistance and metastatic dissemination. Consequently, the discovery of new potent agents that selectively target the hypoxic cell population may reveal new and untapped antitumour mechanisms. Here we demonstrate that the BE-43547 subclass of the APD-CLD (amidopentadienoate-containing cyclolipodepsipeptides) natural products possesses highly hypoxia-selective growth-inhibitory activity against pancreatic cancer cells. To enable this discovery, we have developed the first synthesis of the BE-43547-macrocyclic scaffold in 16 steps (longest linear sequence), which also allowed access to the full panel of relative stereoisomers and ultimately to the assignment of stereochemical configuration...
March 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28221023/polymorph-dependent-electrogenerated-chemiluminescence-of-low-dimensional-organic-semiconductor-structures-for-sensing
#15
Jianmin Gu, Yahui Gao, Jingxiao Wu, Qing Li, Aixue Li, Wei Zhang, Haiyun Dong, Bin Wen, Faming Gao, Yong Sheng Zhao
A sensitive electrogenerated chemiluminescence (ECL) sensor with organic semiconductor as active materials for detecting trace amounts of molecules have been highly desired. However, the crystal structure responses of the ECL properties of the organic semiconductor materials, that is structure-property relationship, is not clear, which limits the development of the sensitive ECL sensors. Herein, for the first time, we reported a novel concept for molecular stacking arrangement dependent electrogenerated chemiluminescence properties of organic semiconductor rubrene microstructures...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28220970/in-situ-growth-of-120-cm-2-ch3-nh3-pbbr3-perovskite-crystal-film-on-fto-glass-for-narrowband-photodetectors
#16
Hua-Shang Rao, Wen-Guang Li, Bai-Xue Chen, Dai-Bin Kuang, Cheng-Yong Su
Organometal trihalide perovskites have been attracting intense attention due to their enthralling optoelectric characteristics. Thus far, most applications focus on polycrystalline perovskite, which however, is overshadowed by single crystal perovskite with superior properties such as low trap density, high mobility, and long carrier diffusion length. In spite of the inherent advantages and significant optoelectronic applications in solar cells and photodetectors, the fabrication of large-area laminar perovskite single crystals is challenging...
February 21, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28218686/natural-products-as-chemopreventive-agents-by-potential-inhibition-of-the-kinase-domain-in-erbb-receptors
#17
Maria Olivero-Acosta, Wilson Maldonado-Rojas, Jesus Olivero-Verbel
Small molecules found in natural products provide therapeutic benefits due to their pharmacological or biological activity, which may increase or decrease the expression of human epidermal growth factor receptor (HER), a promising target in the modification of signaling cascades involved in excessive cellular growth. In this study, in silico molecular protein-ligand docking protocols were performed with AutoDock Vina in order to evaluate the interaction of 800 natural compounds (NPs) from the NatProd Collection (http://www...
February 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28218579/effect-of-obstructive-sleep-apnea-on-carotid-artery-intima-media-thickness-related-to-inflammation
#18
Delei Kong, Zheng Qin, Wei Wang, Jian Kang
PURPOSE: Obstructive sleep apnea hypopnea syndrome (OSAHS) is an independent risk factor for atherosclerosis. To ascertain the effect of OSAHS on the development of atherosclerosis in Chinese OSAHS patients, we evaluated markers of atherosclerosis as well as vascular endothelial function and inflammation. METHODS: Chinese men with polysomnography-diagnosed OSAHS were subgrouped into mild-moderate (n = 28) and severe (n = 54) OSAHS groups on the basis of apnea hypopnea index (AHI) scores...
February 19, 2017: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/28218496/functional-analysis-of-bioactivated-surfaces
#19
Selgai Haidari, Marko Boskov, Ulrike Schillinger, Klaus-Dietrich Wolff, Christian Plank, Andreas Kolk
Common scaffold surfaces, such as titanium, can have side effects, e.g., infections, cytotoxicity, impaired osseointegration or low regeneration rates for bone tissue. These effects lead to poor implant integration or even implant loss. Therefore, bioactive implants are promising instruments in tissue regeneration. Osteoinductive elements, such as growth factors and anti-infectives, support wound healing and bone growth and thereby enable faster osseointegration, even in elderly patients. In this study, titanium surfaces were coated with a poly-(D,L-lactide) (PDLLA) layer containing different concentrations of copolymer-protected gene vectors (COPROGs) to locally provide bone morphogenetic protein-2 (BMP-2) or activated anti-infective agents, such as chlorhexidine gluconate, triclosan and metronidazole, to prevent peri-implantitis...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28218279/multi-constituent-simulation-of-thrombus-deposition
#20
Wei-Tao Wu, Megan A Jamiolkowski, William R Wagner, Nadine Aubry, Mehrdad Massoudi, James F Antaki
In this paper, we present a spatio-temporal mathematical model for simulating the formation and growth of a thrombus. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus (solid) phase. The transport and reactions of 10 chemical and biological species are incorporated using a system of coupled convection-reaction-diffusion (CRD) equations to represent three processes in thrombus formation: initiation, propagation and stabilization. Computational fluid dynamic (CFD) simulations using the libraries of OpenFOAM were performed for two illustrative benchmark problems: in vivo thrombus growth in an injured blood vessel and in vitro thrombus deposition in micro-channels (1...
February 20, 2017: Scientific Reports
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