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https://www.readbyqxmd.com/read/29351288/environmental-enteric-dysfunction-pathways-and-child-stunting-a-systematic-review
#1
Kaitlyn M Harper, Maxine Mutasa, Andrew J Prendergast, Jean Humphrey, Amee R Manges
BACKGROUND: Environmental enteric dysfunction (EED) is commonly defined as an acquired subclinical disorder of the small intestine, characterized by villous atrophy and crypt hyperplasia. EED has been proposed to underlie stunted growth among children in developing countries. A collection of biomarkers, organized into distinct domains, has been used to measure different aspects of EED. Here, we examine whether these hypothesized relationships, among EED domains and between each domain and stunting, are supported by data from recent studies...
January 19, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29350450/cross-sectional-and-longitudinal-analysis-of-nutritional-status-of-school-children-from-bumbire-island-united-republic-of-tanzania
#2
Ornella Comandini, Gabriele Carmignani, Alessandro Cipriano, Giovanni Carmignani, Deodatus Tiba, Elisabetta Marini
OBJECTIVE: To analyze the nutritional status of schoolchildren from Bumbire Island (Tanzania) from cross-sectional and longitudinal perspectives. METHODS: During 2014 and 2015, we collected anthropometric measurements in a sample of 437 schoolchildren (226 males, 211 females; 5-16 years). A sub-sample of 126 children were measured in both surveys. Socio-demographic data have been taken and dietary habits investigated. The accuracy of age data was checked. Malnutrition prevalence was calculated according to the WHO references and the z-score criteria...
January 19, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29349274/long-run-effects-of-early-childhood-exposure-to-cholera-on-final-height-evidence-from-industrializing-japan
#3
Kota Ogasawara, Tatsuki Inoue
Pandemic cholera is one of the most topical and urgent issues in many developing countries. However, although a growing body of research has shown the negative long-run effects of infectious disease exposure on human health, the long-run influences of early childhood exposure to cholera have thus far been understudied. To bridge this gap in the body of knowledge, we draw both on new data describing adult height from 1899 to 1910 from comprehensive official Japanese army records and on data recording the regional variation in the intensity of cholera pandemics...
April 2018: SSM—Population Health
https://www.readbyqxmd.com/read/29339259/perturbations-of-the-gut-microbiome-genes-in-infants-with-atopic-dermatitis-according-to-feeding-type
#4
Min-Jung Lee, Mi-Jin Kang, So-Yeon Lee, Eun Lee, Kangjin Kim, Sungho Won, Dong In Suh, Kyung Won Kim, Youn Ho Sheen, Kangmo Ahn, Bong-Soo Kim, Soo-Jong Hong
BACKGROUND: Perturbations of the infant gut microbiota can shape the development of the immune system and link to the risk of allergic diseases. OBJECTIVE: To understand the role of the gut microbiome in atopic dermatitis, the metagenome of the infant gut microbiome was analyzed according to feeding types. METHODS: The composition of gut microbiota was analyzed in fecal samples from 129 infants (6-month-old) by pyrosequencing, including 66 healthy infants and 63 infants with atopic dermatitis...
January 12, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29338801/how-immediate-and-significant-is-the-outcome-of-training-on-diversified-diets-hygiene-and-food-safety-an-effort-to-mitigate-child-undernutrition-in-rural-malawi
#5
Anitha Seetha, Takuji W Tsusaka, Timalizge W Munthali, Maggie Musukwa, Agnes Mwangwela, Zione Kalumikiza, Tinna Manani, Lizzie Kachulu, Nelson Kumwenda, Mike Musoke, Patrick Okori
OBJECTIVE: The present study examined the impacts of training on nutrition, hygiene and food safety designed by the Nutrition Working Group, Child Survival Collaborations and Resources Group (CORE). DESIGN: Adapted from the 21d Positive Deviance/Hearth model, mothers were trained on the subjects of appropriate complementary feeding, water, sanitation and hygiene (WASH) practices, and aflatoxin contamination in food. To assess the impacts on child undernutrition, a randomised controlled trial was implemented on a sample of 179 mothers and their children (<2 years old) in two districts of Malawi, namely Mzimba and Balaka...
January 17, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29338002/the-associations-between-adult-body-composition-and-abdominal-adiposity-outcomes-and-relative-weight-gain-and-linear-growth-from-birth-to-age-22-in-the-birth-to-twenty-plus-cohort-south-africa
#6
Alessandra Prioreschi, Richard J Munthali, Juliana Kagura, Rihlat Said-Mohamed, Emanuella De Lucia Rolfe, Lisa K Micklesfield, Shane A Norris
BACKGROUND: The growing prevalence of overweight and obesity in low- or middle-income countries precipitates the need to examine early life predictors of adiposity. OBJECTIVES: To examine growth trajectories from birth, and associations with adult body composition in the Birth to Twenty Plus Cohort, Soweto, South Africa. METHODS: Complete data at year 22 was available for 1088 participants (536 males and 537 females). Conditional weight and height indices were generated indicative of relative rate of growth between years 0-2, 2-5, 5-8, 8-18, and 18-22...
2018: PloS One
https://www.readbyqxmd.com/read/29329533/nutritional-status-of-in-school-children-and-its-associated-factors-in-denkyembour-district-eastern-region-ghana-comparing-schools-with-feeding-and-non-school-feeding-policies
#7
Mavis Pearl Kwabla, Charlotte Gyan, Francis Zotor
BACKGROUND: Childhood malnutrition still remains a major public health problem impacting negatively on the academic aptitude of school-aged children (SAC) particularly in limited resource countries. The Government of Ghana in collaboration with the Dutch Government introduced the school feeding programme (SFP) to boost the nutritional status of SAC in the country. This study sought to compare the nutritional status of SAC enrolled in schools with the SFP and SAC enrolled in schools without the SFP in place for the purpose of identifying which group has the higher rate of malnutrition...
January 12, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/29329244/infant-development-at-the-age-of-6-months-in-relation-to-feeding-practices-iron-status-and-growth-in-a-peri-urban-community-of-south-africa
#8
Marinel Rothman, Mieke Faber, Namukolo Covic, Tonderayi M Matsungo, Marike Cockeran, Jane D Kvalsvig, Cornelius M Smuts
BACKGROUND: Evidence on the association between feeding practices, iron deficiency, anaemia, stunting, and impaired psychomotor development during infancy is limited. This study assessed the association between psychomotor development with early feeding practices, growth, iron status, and anaemia. METHODS: This was cross-sectional baseline data of a randomised controlled trial which included 6-month-old infants and their mothers or primary caregivers (n = 750) in a peri-urban community in the North West province of South Africa...
January 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29327329/microrna-mediated-r-gene-regulation-molecular-scabbards-for-double-edged-swords
#9
REVIEW
Yingtian Deng, Minglei Liu, Xiaofei Li, Feng Li
Plant resistance (R) proteins are immune receptors that recognize pathogen effectors and trigger rapid defense responses, namely effector-triggered immunity. R protein-mediated pathogen resistance is usually race specific. During plant-pathogen coevolution, plant genomes accumulated large numbers of R genes. Even though plant R genes provide important natural resources for breeding disease-resistant crops, their presence in the plant genome comes at a cost. Misregulation of R genes leads to developmental defects, such as stunted growth and reduced fertility...
January 9, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29325698/what-causes-childhood-stunting-among-children-of-san-vicente-guatemala-employing-complimentary-system-analysis-approaches
#10
Lee E Voth-Gaeddert, Matthew Stoker, Devin Cornell, Daniel B Oerther
Guatemala has the sixth worst stunting rate with 48% of children under five years of age classified as stunted according to World Health Organization standards. This study utilizes two different yet complimentary system-analysis approaches to analyze correlations among environmental and demographic variables, environmental enteric dysfunction (EED), and child height-for-age (stunting metric) in Guatemala. Two descriptive models constructed around applicable environmental and demographic factors on child height-for-age and EED were analyzed using Network Analysis (NA) and Structural Equation Modeling (SEM)...
January 5, 2018: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29325171/maternal-and-child-health-handbook-use-for-maternal-and-child-care-a-cluster-randomized-controlled-study-in-rural-java-indonesia
#11
Keiko Osaki, Tomoko Hattori, Akemi Toda, Erna Mulati, Lukas Hermawan, Kirana Pritasari, Saptawati Bardosono, Soewarta Kosen
Background: Effectiveness of the Maternal and Child Health Handbook (MCHHB), a home-based booklet for pregnancy, delivery and postnatal/child health, was evaluated on care acquisition and home care in rural Java, a low service-coverage area. Methods: We conducted a health centre-based randomized trial, with a 2-year follow-up. Intervention included (i) MCHHB provision at antenatal care visits; (ii) records and guides by health personnel on and with the MCHHB; and (iii) sensitization of care by volunteers using the MCHHB...
January 9, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29324840/malaria-increased-the-risk-of-stunting-and-wasting-among-young-children-in-ethiopia-results-of-a-cohort-study
#12
Taye Gari, Eskindir Loha, Wakgari Deressa, Tarekegn Solomon, Bernt Lindtjørn
INTRODUCTION: Given the high prevalence of malnutrition in a malaria-endemic setting, improving nutritional status could serve as a tool to prevent malaria. However, the relationship between the two conditions remains unclear. Therefore, this study assessed the association between under-nutrition and malaria among a cohort of children aged 6 to 59 months old. METHODS: Two cohorts of children were followed for 89 weeks in a rural Rift Valley area of Ethiopia. In the first approach (malaria-malnutrition), a cohort of 2,330 non-stunted and 4,204 non-wasted children were included to assess under-nutrition (outcome) based on their previous malaria status (exposure)...
2018: PloS One
https://www.readbyqxmd.com/read/29317193/an-essential-role-for-neuregulin-4-in-the-growth-and-elaboration-of-developing-neocortical-pyramidal-dendrites
#13
Blanca Paramo, Sean Wyatt, Alun M Davies
Neuregulins, with the exception of neuregulin-4 (NRG4), have been shown to be extensively involved in many aspects of neural development and function and are implicated in several neurological disorders, including schizophrenia, depression and bipolar disorder. Here we provide the first evidence that NRG4 has a crucial function in the developing brain. We show that both the apical and basal dendrites of neocortical pyramidal neurons are markedly stunted in Nrg4-/- neonates in vivo compared with Nrg4+/+ littermates...
January 6, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29316505/molecular-dissection-of-distinct-symptoms-induced-by-tomato-chlorosis-virus-and-tomato-yellow-leaf-curl-virus-based-on-comparative-transcriptome-analysis
#14
Jang-Kyun Seo, Mi-Kyeong Kim, Hae-Ryun Kwak, Hong-Soo Choi, Moon Nam, Junkyoung Choe, Boram Choi, Soo-Jung Han, Jin-Ho Kang, Choonkyun Jung
The viral infection of plants may cause various physiological symptoms associated with the reprogramming of plant gene expression. However, the molecular mechanisms and associated genes underlying disease symptom development in plants infected with viruses are largely unknown. In this study, we employed RNA sequencing for in-depth molecular characterization of the transcriptional changes associated with the development of distinct symptoms induced by tomato chlorosis virus (ToCV) and tomato yellow leaf curl virus (TYLCV) in tomato...
January 6, 2018: Virology
https://www.readbyqxmd.com/read/29316273/pilot-project-physiologic-responses-to-a-high-intensity-active-video-game-with-copd-patients-tools-for-home-rehabilitation
#15
Andrée-Anne Parent, Vincent Gosselin-Boucher, Marilyn Houle-Peloquin, Claude Poirier, Alain-Steve Comtois
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is a respiratory condition that causes a significant deterioration of the quality of life. However, exercise can improve the quality of life for COPD patients and it is for this reason previous study observed the effects of active video games to increase exercise. Using motion capture devices with short bursts of exercise never been tried with COPD patients. OBJECTIVES: The objective was to observe the feasibility of using this device safely and easily with COPD patients...
January 8, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29315413/let-us-talk-about-stunting
#16
Anuradha Bose
No abstract text is available yet for this article.
January 5, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29309520/causal-effect-of-parental-schooling-on-early-childhood-undernutrition-quasi-experimental-evidence-from-zimbabwe
#17
Jan-Walter De Neve, S V Subramanian
An estimated 3.1 million children die each year because of undernutrition. Although cross-sectional and longitudinal studies have found a protective association between greater parental education and undernutrition in their children, no randomized trial has identified a causal effect, to our knowledge. Using the 1980 education reform in Zimbabwe as a natural experiment, we estimated the causal effect of additional parental schooling on the probability of anthropometric failure in their children under 5 years of age (ages 3 through 59 months)...
January 1, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29303692/molecular-identification-and-characterization-of-the-new-16srix-j-and-cpn60-ut-ix-j-phytoplasma-subgroup-associated-with-chicory-bushy-stunt-disease-in-saudi-arabia
#18
Edel Pérez-López, Ayman F Omar, Khaled M Al-Jamhan, Tim J Dumonceaux
Chicory (Cichorium intybus) is a perennial plant (Asteraceae) that grows wild in pasture fields in Saudi Arabia. Chicory plants displaying symptoms typically induced by phytoplasmas, such as bushy phenotype and stunt, were observed in the Mulayda region, Qassim governorate, Saudi Arabia. In this study we examined samples taken from three symptomatic chicory plants and confirmed the presence of phytoplasma DNA. Analysis of the 16S rRNA-encoding sequences showed that the plants were infected with a phytoplasma from the pigeon pea witches'-broom group (16SrIX)...
January 5, 2018: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29302321/developmental-and-behavioural-problems-in-children-with-severe-acute-malnutrition-in-malawi-a-cross-sectional-study
#19
Meta van den Heuvel, Wieger Voskuijl, Kate Chidzalo, Marko Kerac, Sijmen A Reijneveld, Robert Bandsma, Melissa Gladstone
Background: Early childhood development provides an important foundation for the development of human capital. Although there is a clear relation between stunting and child development outcomes, less information is available about the developmental and behavioural outcomes of children with severe acute malnutrition (SAM). Particularly an important research gap exists in Sub-Saharan Africa where there is a high prevalence of SAM and a high rate of co-occurring HIV (human immune deficiency virus) infection...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29301293/assessment-of-nutritional-status-of-infants-living-in-arsenic-contaminated-areas-in-bangladesh-and-its-association-with-arsenic-exposure
#20
Abul Hasnat Milton, John Attia, Mohammad Alauddin, Mark McEvoy, Patrick McElduff, Sumaira Hussain, Ayesha Akhter, Shahnaz Akter, M Munirul Islam, A M Shamsir Ahmed, Vasu Iyengar, Md Rafiqul Islam
Data is scarce on early life exposure to arsenic and its association with malnutrition during infancy. This study followed the nutritional status of a cohort of 120 infants from birth to 9 months of age in an arsenic contaminated area in Bangladesh. Anthropometric data was collected at 3, 6 and 9 months of the infant's age for nutritional assessment whereas arsenic exposure level was assessed via tube well drinking water arsenic concentration at the initiation of the study. Weight and height measurements were converted to Z-scores of weight for age (WAZ-underweight), height for age (HAZ-stunting), weight for height (WHZ-wasting) for children by comparing with WHO growth standard...
January 2, 2018: International Journal of Environmental Research and Public Health
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