keyword
MENU ▼
Read by QxMD icon Read
search

Trauma

keyword
https://www.readbyqxmd.com/read/28655133/the-effect-of-traumatic-brain-injury-history-with-loss-of-consciousness-on-rate-of-cognitive-decline-among-older-adults-with-normal-cognition-and-alzheimer-s-disease-dementia
#1
Yorghos Tripodis, Michael L Alosco, Nikolaos Zirogiannis, Brandon E Gavett, Christine Chaisson, Brett Martin, Michael D McClean, Jesse Mez, Neil Kowall, Robert A Stern
Traumatic brain injury (TBI) is thought to be a risk factor for dementia, including dementia due to Alzheimer's disease (AD). However, the influence of TBI history on the neuropsychological course of AD is unknown and, more broadly, the effect of TBI history on age-related cognitive change is poorly understood. We examined the relationship between history of TBI with loss of consciousness (LOC) history and cognitive change in participants with normal cognition and probable AD, stratified by APOEɛ4 allele status...
June 22, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28654944/perceptually-salient-sound-distortions-and-apraxia-of-speech-a-performance-continuum
#2
Katarina L Haley, Adam Jacks, Jessica D Richardson, Julie L Wambaugh
Purpose: We sought to characterize articulatory distortions in apraxia of speech and aphasia with phonemic paraphasia and to evaluate the diagnostic validity of error frequency of distortion and distorted substitution in differentiating between these disorders. Method: Study participants were 66 people with speech sound production difficulties after left-hemisphere stroke or trauma. They were divided into 2 groups on the basis of word syllable duration, which served as an external criterion for speaking rate in multisyllabic words and an index of likely speech diagnosis...
June 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28654847/a-model-comparison-approach-to-trauma-related-guilt-as-a-mediator-of-the-relationship-between-ptsd-symptoms-and-suicidal-ideation-among-veterans
#3
Katherine C Cunningham, Chloe Farmer, Stefanie T LoSavio, Paul A Dennis, Carolina P Clancy, Michael A Hertzberg, Claire F Collie, Patrick S Calhoun, Jean C Beckham
BACKGROUND: Suicidal ideation (SI) is a serious issue affecting U.S. veterans, and those with posttraumatic stress disorder (PTSD) are at an especially high risk of SI. Guilt has been associated with both PTSD and SI and may therefore be an important link between these constructs. METHODS: The present study compared models of trauma-related guilt and used path analysis to examine the direct and indirect effects of PTSD and trauma-related guilt on SI among a sample of 988 veterans receiving outpatient PTSD treatment at a Veterans Affairs (VA) specialty clinic...
June 21, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28654774/fkbp5-moderation-of-the-relationship-between-childhood-trauma-and-maladaptive-emotion-regulation-strategies-in-adolescents
#4
Thorhildur Halldorsdottir, Ana Paula Soares de Matos, Yvonne Awaloff, Eiríkur Örn Arnarson, W Edward Craighead, Elisabeth B Binder
Maladaptive emotion regulation strategies, such as rumination and catastrophizing, are transdiagnostic risk factors for psychopathology. FK506-binding protein 51 (FKBP5) has been found to moderate the relationship between stressful life events and various psychiatric disorders. Given the cross-disorder moderation effect of FKBP5 at the diagnostic level, the aim of the current study was to examine whether the relationship between exposure to childhood trauma and transdiagnostic maladaptive emotion regulation processes would also be moderated by genetic FKBP5 variation in a community sample of adolescents...
June 17, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28654581/improved-rates-of-immediate-breast-reconstruction-at-safety-net-hospitals
#5
Tiffany N S Ballard, Lin Zhong, Adeyiza O Momoh, Kevin C Chung, Jennifer F Waljee
BACKGROUND: Substantial federal resources have been directed toward ensuring the delivery of high-quality care at safety net hospitals. Although disparities in receipt of breast reconstruction persist at the patient level, the extent to which hospital factors contribute to these differences remains unclear. The rates of immediate breast reconstruction across safety net and non-safety net hospitals were investigated. METHODS: Women 21 years and older with breast cancer or increased risk of breast cancer undergoing immediate post-mastectomy reconstruction were identified in the Nationwide Inpatient Sample database...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28654462/depressed-gut-the-microbiota-diet-inflammation-trialogue-in-depression
#6
Judith K Daniels, Margreet Koopman, Sahar El Aidy
PURPOSE OF REVIEW: According to the WHO reports, around 350 billion people worldwide suffer from depression. Despite its high prevalence, the complex interaction of multiple mechanisms underlying depression still needs to be elucidated. RECENT FINDINGS: Over the course of the last few years, several neurobiological alterations have been linked to the development and maintenance of depression. One basic process that seems to link many of these findings is inflammation...
June 24, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28654444/lichenoid-dermatitis-of-the-vulva-diagnosis-and-differential-diagnosis-for-the-gynecologic-pathologist
#7
Marc R Lewin, Ryan W Hick, Maria A Selim
Inflammatory processes affecting the vulva may present a unique challenge due to location specific changes. Different factors are behind the intricacy in the presentation of vulvar dermatoses. First, the vulva is lined by different epithelia (hair-bearing keratinized epithelium, modified mucosa, and mucosa). Furthermore, among other factors, this organ is exposed to friction, occlusion, and trauma. Lastly, as there is a tendency to look for health care advice at an advanced stage of the disease, the lesion may be modified by secondary changes due to self-treatment...
June 26, 2017: Advances in Anatomic Pathology
https://www.readbyqxmd.com/read/28654094/inflammation-and-vascular-remodeling-in-the-ventral-hippocampus-contributes-to-vulnerability-to-stress
#8
J Pearson-Leary, D Eacret, R Chen, H Takano, B Nicholas, S Bhatnagar
During exposure to chronic stress, some individuals engage in active coping behaviors that promote resiliency to stress. Other individuals engage in passive coping that is associated with vulnerability to stress and with anxiety and depression. In an effort to identify novel molecular mechanisms that underlie vulnerability or resilience to stress, we used nonbiased analyses of microRNAs in the ventral hippocampus (vHPC) to identify those miRNAs differentially expressed in active (long-latency (LL)/resilient) or passive (short-latency (SL)/vulnerable) rats following chronic social defeat...
June 27, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28654066/a-mouse-model-of-single-and-repetitive-mild-traumatic-brain-injury
#9
Bevan S Main, Stephanie S Sloley, Sonia Villapol, David N Zapple, Mark P Burns
Mild Traumatic Brain Injury (mTBI) can result in the acute loss of brain function, including a period of confusion, a loss of consciousness (LOC), focal neurological deficits and even amnesia. Athletes participating in contact sports are at high risk of exposure to large number of mTBIs. In terms of the level of injury in a sporting athlete, a mTBI is defined as a mild injury that does not cause gross pathological changes, but does cause short-term neurological deficits that are spontaneously resolved. Despite previous attempts to model mTBI in mice and rats, many have reported gross adverse effects including skull fractures, intracerebral bleeding, axonal injury and neuronal cell death...
June 20, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28654057/murine-aortic-crush-injury-an-efficient-in-vivo-model-of-smooth-muscle-cell-proliferation-and-endothelial-function
#10
Dan Yu, George Makkar, Rajabrata Sarkar, Dudley K Strickland, Thomas S Monahan
Arterial reconstruction, whether angioplasty or bypass surgery, involves iatrogenic trauma causing endothelial disruption and vascular smooth muscle cell (VSMC) proliferation. Common murine models study small vessels such as the carotid and femoral arteries. Herein we describe an in vivo system in which both VSMC proliferation and endothelial barrier function can be simultaneously assessed in a large vessel. We studied the infrarenal aortic response to injury in C57BL/6 mice. The aorta was injured from the left renal vein to the aortic bifurcation by 30 transmural crushes of 5-seconds duration with a cotton-tipped applicator...
June 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28654038/rewiring-neuronal-circuits-a-new-method-for-fast-neurite-extension-and-functional-neuronal-connection
#11
Margaret H Magdesian, Madeleine Anthonisen, G Monserratt Lopez-Ayon, Xue Ying Chua, Matthew Rigby, Peter Grütter
Brain and spinal cord injury may lead to permanent disability and death because it is still not possible to regenerate neurons over long distances and accurately reconnect them with an appropriate target. Here a procedure is described to rapidly initiate, elongate, and precisely connect new functional neuronal circuits over long distances. The extension rates achieved reach over 1.2 mm/h, 30-60 times faster than the in vivo rates of the fastest growing axons from the peripheral nervous system (0.02 to 0.04 mm/h)(28) and 10 times faster than previously reported for the same neuronal type at an earlier stage of development(4)...
June 13, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28653646/early-predictors-of-outcome-after-mild-traumatic-brain-injury-upfront-an-observational-cohort-study
#12
Joukje van der Naalt, Marieke E Timmerman, Myrthe E de Koning, Harm J van der Horn, Myrthe E Scheenen, Bram Jacobs, Gerard Hageman, Tansel Yilmaz, Gerwin Roks, Jacoba M Spikman
BACKGROUND: Mild traumatic brain injury (mTBI) accounts for most cases of TBI, and many patients show incomplete long-term functional recovery. We aimed to create a prognostic model for functional outcome by combining demographics, injury severity, and psychological factors to identify patients at risk for incomplete recovery at 6 months. In particular, we investigated additional indicators of emotional distress and coping style at 2 weeks above early predictors measured at the emergency department...
July 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28653442/attachment-and-dissociation-as-mediators-of-the-link-between-childhood-trauma-and-psychotic-experiences
#13
Josie Pearce, Jane Simpson, Katherine Berry, Sandra Bucci, Andrew Moskowitz, Filippo Varese
Exposure to childhood trauma has been implicated in the development of paranoia and hearing voices, but the mechanisms responsible for these associations remain unclear. Understanding these mechanisms is essential for ensuring that targeted interventions can be developed to better support people experiencing distress associated with paranoia and voices. Recent models have proposed that dissociation may be a mechanism specifically involved in the development of voices and insecure attachment in the development of paranoia...
June 27, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28653434/injury-from-falls-in-infants-under-one-year
#14
Christopher S Mulligan, Susan Adams, Dimitra Tzioumi, Julie Brown
AIM: Falls in infants are a common cause of injury. Compared to older children, infants under age one are likely to have distinctive causation and injury patterns, as they are pre-mobile or have limited independent mobility and falls are more directly the responsibility of the care giver. There is little known about the mechanistic factors, predictors of injury and injury patterns in this age group. METHODS: We conducted a retrospective review of infants under age one who presented after a fall to a paediatric trauma centre in Sydney, Australia...
June 26, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28653376/has-the-income-of-the-residential-area-impact-on-the-use-of-intensive-care
#15
J H Liisanantti, R Käkelä, L V Raatiniemi, P Ohtonen, S Hietanen, T I Ala-Kokko
BACKGROUND: The socioeconomic factors have an impact on case mix and outcome in critical illness, but how these factors affect the use of intensive care is not studied. The aim of this study was to evaluate the incidence of intensive care unit (ICU) admissions in patients from residential areas with different annual incomes. METHODS: Single-center, retrospective study in Northern Finland. All the non-trauma-related emergency admissions from the hospital district area were included...
June 26, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28653339/fibrinogen-concentration-and-use-of-fibrinogen-supplementation-with-cryoprecipitate-in-patients-with-critical-bleeding-receiving-massive-transfusion-a-bi-national-cohort-study
#16
Zoe K McQuilten, Michael Bailey, Peter A Cameron, Simon J Stanworth, Kylie Venardos, Erica M Wood, D James Cooper
We aimed to compare hypofibrinogenaemia prevalence in major bleeding patients across all clinical contexts, fibrinogen supplementation practice, and explore the relationship between fibrinogen concentrations and mortality. This cohort study included all adult patients from 20 hospitals across Australia and New Zealand who received massive transfusion between April 2011 and October 2015. Of 3566 patients, 2829 (79%) had fibrinogen concentration recorded, with a median first and lowest concentration of 2·0 g/l (interquartile range [IQR] 1·5-2·7) and 1·8 g/l (IQR 1·3-2·4), respectively...
June 27, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28653327/are-severely-injured-trauma-victims-in-norway-offered-advanced-pre-hospital-care-national-retrospective-observational-cohort
#17
T Wisborg, E N Ellensen, I Svege, T Dehli
BACKGROUND: Studies of severely injured patients suggest that advanced pre-hospital care and/or rapid transportation provides a survival benefit. This benefit depends on the disposition of resources to patients with the greatest need. Norway has 19 Emergency Helicopters (HEMS) staffed by anaesthesiologists on duty 24/7/365. National regulations describe indications for their use, and the use of the national emergency medical dispatch guideline is recommended. We assessed whether severely injured patients had been treated or transported by advanced resources on a national scale...
June 26, 2017: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/28653305/volumetric-evaluation-of-temporal-bone-structures-in-the-cases-with-bilateral-tinnitus-clinical-and-morphometrical-study
#18
Nuket Gocmen Mas, Orhan Kahveci, Sevda Lafcı Fahrioğlu, Nazan Okur, Sinan Canan, Nilufer Demirci Yonguc, Oktay Özel, Selim Karabekir
BACKGROUND: Tinnitus is the recognition of sound in the absence of any external auditory stimulus to the noise of ringing in the ears. Middle ear aeration carries important role for ossicular coupling and normal hearing. There is restricted morphometric data on the cases with bilateral tinnitus. MATERIAL AND METHODS: In this study we evaluated hearing findings of 18 cases with subjective nonpulsatile bilateral tinnitus and also morphometry and volumetry of temporal bone substructures on the Computed Tomography images using Stereological Method compared with the gender and age matched 12 healthy subjects...
June 27, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28653261/future-enhanced-clinical-role-of-pharmacists-in-emergency-departments-in-england-multi-site-observational-evaluation
#19
Elizabeth Hughes, David Terry, Chi Huynh, Konstantinos Petridis, Matthew Aiello, Louis Mazard, Hirminder Ubhi, Alex Terry, Keith Wilson, Anthony Sinclair
Background There are concerns about maintaining appropriate clinical staffing levels in Emergency Departments. Pharmacists may be one possible solution. Objective To determine if Emergency Department attendees could be clinically managed by pharmacists with or without advanced clinical practice training. Setting Prospective 49 site cross-sectional observational study of patients attending Emergency Departments in England. Method Pharmacist data collectors identified patient attendance at their Emergency Department, recorded anonymized details of 400 cases and categorized each into one of four possible options: cases which could be managed by a community pharmacist; could be managed by a hospital pharmacist independent prescriber; could be managed by a hospital pharmacist independent prescriber with additional clinical training; or medical team only (unsuitable for pharmacists to manage)...
June 26, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28653162/completely-intracorporeal-handsewn-laparoscopic-anastomoses-during-whipple-procedure
#20
Giovanni Dapri, Nigel Antonio Bascombe, Leonardo Gerard, Carla Samaniego Ballart, Carlos Gimenez Viñas, Sven Saussez
BACKGROUND: Whipple procedure has been described since 1935,1 using classic open surgery. With the advent of minimally invasive surgery (MIS), it has been described to be feasible using the latest technology.2 (,) 3 In this video the authors report a full laparoscopic Whipple procedure, realizing the three anastomoses by intracorporeal handsewn method. VIDEO: A 70-year-old man who presented with adenocarcinoma of the ampulla of Vater, infiltrating the pancreatic parenchyma underwent to a laparoscopic Whipple...
June 26, 2017: Annals of Surgical Oncology
keyword
keyword
129
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"