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https://www.readbyqxmd.com/read/28529306/normalization-of-diffuse-st-depression-with-avr-elevation-after-rehydration-in-a-patient-with-severe-aortic-stenosis
#1
Sachin R Patel, Vikas J Patel, Brittany Clark, George Rust
BACKGROUND Isolated ST elevation in lead aVR in combination with global ST depression with normalization after rehydration is a unique electrocardiographic pattern that is associated with a broad range of diagnoses. Its association with left main coronary artery disease and other acute coronary syndromes suggest the need for early and aggressive cardiac evaluation. CASE REPORT A 53-year-old man presented with altered mental status and loss of consciousness. He was unresponsive, hypotensive, tachycardiac, and diaphoretic...
May 22, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28525541/safety-behaviors-and-stuttering
#2
Robyn Lowe, Fjola Helgadottir, Ross Menzies, Rob Heard, Sue O'Brian, Ann Packman, Mark Onslow
Purpose: Those who are socially anxious may use safety behaviors during feared social interactions to prevent negative outcomes. Safety behaviors are associated with anxiety maintenance and poorer treatment outcomes because they prevent fear extinction. Social anxiety disorder is often comorbid with stuttering. Speech pathologists reported in a recent publication (Helgadottir, Menzies, Onslow, Packman, & O'Brian, 2014a) that they often recommended procedures for clients that could be safety behaviors...
May 19, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28515502/ismp-adverse-drug-reactions-pregabalin-induced-stuttering-nitroglycerine-induced-bradycardia-progressing-to-asystole-minocycline-induced-dress-leading-to-liver-transplantation-and-type-1-diabetes-increased-risk-of-vertebral-fractures-in-women-receiving-thiazide
#3
Michael A Mancano
The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Write to Dr. Mancano at ISMP, 200 Lakeside Drive, Suite 200, Horsham, PA 19044 (phone: 215-707-4936; e-mail: mmancano@temple.edu). Your report will be published anonymously unless otherwise requested...
April 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/28511232/-priapism-in-children-and-adolescents
#4
Abhishek Pandey, Hansjörg Keller
Priapism is a prolonged erection without sexual stimulation. In most cases it requires prompt management in order to avoid long-term consequences such as erectile dysfunction or penile deformity. Priapism is rare in children, but haematological diseases play an important role. The diagnosis is generally not difficult. Blood gas analysis and Doppler sonography are used to establish the form of priapism and determine its further management. The management of low-flow priapism consists of immediate blood aspiration and intracavernosal injection of sympathomimetic drugs as needed...
May 16, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28500247/man-stops-stuttering-with-alcohol-dependence-drug
#5
Zosia Kmietowicz
No abstract text is available yet for this article.
May 11, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28497957/crimp-accumulation-and-compression-of-billions-of-ions-for-ion-mobility-ms-using-traveling-waves-in-structures-for-lossless-ion-manipulations
#6
Liulin Deng, Sandilya V B Garimella, Ahmed M Hamid, Ian K Webb, Isaac K Attah, Randolph V Norheim, Spencer A Prost, Xueyun Zheng, Jeremy A Sandoval, Erin Shammel Baker, Yehia M Ibrahim, Richard D Smith
We report on the implementation of a traveling wave (TW) based compression ratio ion mobility programming (CRIMP) approach within Structures for Lossless Ion Manipulations (SLIM) that enables both greatly enlarged trapped ion charge capacities and also efficient ion population compression for use in ion mobility (IM) separations. Ion accumulation is conducted in a SLIM serpentine ultra-long path with extended routing (SUPER) region after which CRIMP compression allows the large ion populations to be 'squeezed'...
May 12, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28495786/speaking-fluently-with-baclofen
#7
Esther Beraha, Pieter Bodewits, Wim van den Brink, Reinout Wiers
Baclofen is a new and promising pharmacological compound for the treatment of alcohol dependence (AD). Although several randomised trials found a reduction of craving and higher abstinence rates with low and high doses of baclofen, others failed to show positive effects. In this case study, the successful treatment of a patient with AD with daily 120 mg of baclofen is described. In addition to a decrease in alcohol use, we observed the cessation of stuttering during treatment with baclofen, reoccurrence of stuttering following discontinuation, and cessation of stuttering after reinstatement of the treatment...
May 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28487827/an-automatic-prolongation-detection-approach-in-continuous-speech-with-robustness-against-speaking-rate-variations
#8
Iman Esmaili, Nader Jafarnia Dabanloo, Mansour Vali
In recent years, many methods have been introduced for supporting the diagnosis of stuttering for automatic detection of prolongation in the speech of people who stutter. However, less attention has been paid to treatment processes in which clients learn to speak more slowly. The aim of this study was to develop a method to help speech-language pathologists (SLPs) during diagnosis and treatment sessions. To this end, speech signals were initially parameterized to perceptual linear predictive (PLP) features...
January 2017: Journal of Medical Signals and Sensors
https://www.readbyqxmd.com/read/28483857/cortical-dynamics-of-disfluency-in-adults-who-stutter
#9
Ranit Sengupta, Shalin Shah, Torrey M J Loucks, Kristin Pelczarski, J Scott Yaruss, Katie Gore, Sazzad M Nasir
Stuttering is a disorder of speech production whose origins have been traced to the central nervous system. One of the factors that may underlie stuttering is aberrant neural miscommunication within the speech motor network. It is thus argued that disfluency (any interruption in the forward flow of speech) in adults who stutter (AWS) could be associated with anomalous cortical dynamics. Aberrant brain activity has been demonstrated in AWS in the absence of overt disfluency, but recording neural activity during disfluency is more challenging...
May 2017: Physiological Reports
https://www.readbyqxmd.com/read/28483259/cortical-auditory-evoked-potentials-in-children-who-stutter
#10
Naema Ismail, Yossra Sallam, Reda Behery, Ameera Al Boghdady
INTRODUCTION: It has been hypothesized that impaired auditory processing influence the occurrence of stuttering. Also, it is suggested that speech perception in children who stutter differed from normal. Auditory processing should be investigated in children who stutter shortly after the onset of stuttering in order to evaluate the extent to which impaired auditory processing contributes to the development of stuttering. CAEPs provide the necessary temporal and spatial resolution to detect differences in auditory processing and the neural activity that is related or time-locked to the auditory stimulus...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28480849/impact-of-internet-gambling-on-mental-and-psychological-health-of-children-of-various-ages
#11
M Khundadze, N Geladze, N Kapanadze
The aim of the study was to assess the impact of internet gambling on children's mental and physical health and find correlation between the age, duration of internet use and type of comorbidity associated with internet gambling. The study assessed 50 patients with internet gambling (35 boys, 15 girls) from 2013-2016 y. The age range was 3-15 years. 15 patients were from 3-7 y of age, 20 patients from 7-12 y and 15 - from 12-15 y of age. The core problem common for all patients were internet overuse by computer games, mobile device and other gadgets...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28475659/fear-of-negative-evaluation-trait-anxiety-and-judgment-bias-in-adults-who-stutter
#12
Shelley B Brundage, Katherine L Winters, Janet M Beilby
Purpose: Persons who stutter (PWS) and those with social anxiety disorder may exhibit fear of negative evaluation (FNE) and anxiety in social situations. However, the information processing biases that perpetuate these characteristics have had limited investigation. This study investigated judgment bias in social situations. Method: Participants included 50 adults who stutter and 45 age- and gender-matched fluent persons who do not stutter (PWNS), who made up the control group...
May 17, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28470081/a-comparison-of-attitudes-towards-stuttering-of-non-stuttering-preschoolers-in-the-united-states-and-turkey
#13
Mary E Weidner, Kenneth O St Louis, Egemen Nakisci, Ramazan S Ozdemir
BACKGROUND AND OBJECTIVES: Extensive research documents ubiquitous negative attitudes towards stuttering, but when and how they develop is unclear. This non-experimental, comparative study examined US and Turkish preschoolers to explore the origin of stuttering attitudes cross-culturally. METHOD: The authors compared stuttering attitudes of 28 US and 31 Turkish non-stuttering preschoolers on English and Turkish versions of experimental prototypes of the newly developed Public Opinion Survey on Human Attributes-Stuttering/Child (POSHA-S/Child)...
April 21, 2017: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://www.readbyqxmd.com/read/28445836/a-forensic-multiplex-of-nine-novel-pentameric-repeat-strs
#14
M de la Puente, C Phillips, M Fondevila, M Gelabert-Besada, Á Carracedo, M V Lareu
Pentameric-repeat short tandem repeats (STRs), consisting of loci with repeat units of five base-pairs, have the advantage of reduced stutter products compared to their tetrameric-repeat STR counterparts. This characteristic potentially helps the interpretation of mixed DNA profiles when minor component alleles may coincide with stutter peaks from the major components. To develop a simple but informative forensic multiplex with the capability to aid mixture interpretation, we designed an 11-plex assay of nine pentameric STRs new to forensic analysis plus two male- specific markers: DYS391 and the Y-Indel rs2032678 used in GlobalFiler™ (Life Technologies)...
April 15, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28432288/overexpression-of-human-nr2b-receptor-subunit-in-lman-causes-stuttering-and-song-sequence-changes-in-adult-zebra-finches
#15
Mukta Chakraborty, Liang-Fu Chen, Emma E Fridel, Marguerita E Klein, Rebecca A Senft, Abhra Sarkar, Erich D Jarvis
Zebra finches (Taeniopygia guttata) learn to produce songs in a manner reminiscent of spoken language development in humans. One candidate gene implicated in influencing learning is the N-methyl-D-aspartate (NMDA) subtype 2B glutamate receptor (NR2B). Consistent with this idea, NR2B levels are high in the song learning nucleus LMAN (lateral magnocellular nucleus of the anterior nidopallium) during juvenile vocal learning, and decreases to low levels in adults after learning is complete and the song becomes more stereotyped...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28431323/transcranial-magnetic-stimulation-in-developmental-stuttering-relations-with-previous-neurophysiological-research-and-future-perspectives
#16
REVIEW
P Busan, P P Battaglini, M Sommer
Developmental stuttering (DS) is a disruption of the rhythm of speech, and affected people may be unable to execute fluent voluntary speech. There are still questions about the exact causes of DS. Evidence suggests there are differences in the structure and functioning of motor systems used for preparing, executing, and controlling motor acts, especially when they are speech related. Much research has been obtained using neuroimaging methods, ranging from functional magnetic resonance to diffusion tensor imaging and electroencephalography/magnetoencephalography...
June 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28418529/anxiety-in-11-year-old-children-who-stutter-findings-from-a-prospective-longitudinal-community-sample
#17
Kylie A Smith, Lisa Iverach, Susan O'Brian, Fiona Mensah, Elaina Kefalianos, Anna Hearne, Sheena Reilly
Purpose: To examine if a community sample of 11-year-old children with persistent stuttering have higher anxiety than children who have recovered from stuttering and nonstuttering controls. Method: Participants in a community cohort study were categorized into 3 groups: (a) those with persistent stuttering, (b) those with recovered stuttering, and (c) nonstuttering controls. Linear regression modeling compared outcomes on measures of child anxiety and emotional and behavioral functioning for the 3 groups...
April 16, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28413060/stuttering-treatment-and-brain-research-in-adults-a-still-unfolding-relationship
#18
REVIEW
Roger J Ingham, Janis C Ingham, Harald A Euler, Katrin Neumann
PURPOSE: Brain imaging and brain stimulation procedures have now been used for more than two decades to investigate the neural systems that contribute to the occurrence of stuttering in adults, and to identify processes that might enhance recovery from stuttering. The purpose of this paper is to review the extent to which these dual lines of research with adults who stutter have intersected and whether they are contributing towards the alleviation of this impairment. METHOD: Several areas of research are reviewed in order to determine whether research on the neurology of stuttering is showing any potential for advancing the treatment of this communication disorder: (a) attempts to discover the neurology of stuttering, (b) neural changes associated with treated recovery, and (c) direct neural intervention...
February 28, 2017: Journal of Fluency Disorders
https://www.readbyqxmd.com/read/28409657/estimates-of-functional-cerebral-hemispheric-differences-in-monolingual-and-bilingual-people-who-stutter-dual-task-paradigm
#19
Myriam Kornisch, Michael P Robb, Richard D Jones
The inter-relationship of stuttering and bilingualism to functional cerebral hemispheric processing was examined on a dual-task paradigm. Eighty native German (L1) speakers, half of whom were sequential bilinguals (L2 = English), were recruited. The participants (mean age = 38.9 years) were organised into four different groups according to speech status and language ability: 20 bilinguals who stutter (BWS), 20 monolinguals who stutter (MWS), 20 bilinguals who do not stutter (BWNS), and 20 monolinguals who do not stutter (MWNS)...
2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28400266/eeg-mu-%C3%A2%C2%B5-rhythm-spectra-and-oscillatory-activity-differentiate-stuttering-from-non-stuttering-adults
#20
Tim Saltuklaroglu, Ashley W Harkrider, David Thornton, David Jenson, Tiffani Kittilstved
Stuttering is linked to sensorimotor deficits related to internal modeling mechanisms. This study compared spectral power and oscillatory activity of EEG mu (μ) rhythms between persons who stutter (PWS) and controls in listening and auditory discrimination tasks. EEG data were analyzed from passive listening in noise and accurate (same/different) discrimination of tones or syllables in quiet and noisy backgrounds. Independent component analysis identified left and/or right μ rhythms with characteristic alpha (α) and beta (β) peaks localized to premotor/motor regions in 23 of 27 people who stutter (PWS) and 24 of 27 controls...
April 8, 2017: NeuroImage
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