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https://www.readbyqxmd.com/read/28749587/regional-survey-supports-national-initiative-for-water-only-schools-in-new-zealand
#1
Osman David Mansoor, Rukhsana Ali, Ruth Richards
OBJECTIVE: To support a national initiative to remove sugary drinks from schools and limit drinks to water or unflavoured milk ('water-only'). METHODS: We emailed all 201 schools with primary school aged children in the Greater Wellington region with a survey on (1) current status of, (2) support needs for, and (3) barriers to or lessons learned from, a 'water-only' school policy. RESULTS: Only 78 (39%) of schools responded. Most supported 'water-only': 22 (28%) had implemented a policy; 10 (13%) in process of doing so; 22 (28%) were considering it; and 12 (15%) were 'water-only', but did not have a policy...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749529/effect-and-acceptance-of-silver-diamine-fluoride-treatment-on-dental-caries-in-primary-teeth
#2
Jennifer Clemens, Jaana Gold, Jeffrey Chaffin
OBJECTIVES: Silver diamine fluoride (SDF) treatment has been identified as a potential solution to address the dental public health issues of untreated dental caries and insufficient access to care. The current study assessed the effectiveness of 38 percent SDF in arresting active dental caries lesions and in reducing or preventing associated dental pain and infections in young, at-risk children. METHODS: We enrolled 32 children aged 2-5 years with 118 active caries lesions in primary teeth from a community dental clinic in Oregon...
July 27, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28749281/neoplasia-in-snakes-at-zoo-atlanta-during-1992-2012
#3
Annie Page-Karjian, Megan Hahne, Kate Leach, Hayley Murphy, Brad Lock, Samuel Rivera
A retrospective study was conducted to review neoplasia of captive snakes in the Zoo Atlanta collection from 1992 to 2012. Of 255 snakes that underwent necropsy and histopathologic examination at Zoo Atlanta during the study period, 37 were observed with neoplasia at necropsy. In those 37 snakes, 42 neoplastic lesions of 18 primary cell types were diagnosed. Thirty-five of those neoplasms (83.3%) were malignant, and of those, 19 were of mesenchymal origin, whereas 14 were of epithelial origin. The median annual rate of neoplasia at necropsy was 12...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749178/validation-and-recalibration-of-the-framingham-cardiovascular-disease-risk-models-in-an-australian-indigenous-cohort
#4
Xinyang Hua, Robyn McDermott, Thomas Lung, Mark Wenitong, An Tran-Duy, Ming Li, Philip Clarke
Background In Australia, clinical guidelines for primary prevention of cardiovascular disease recommend the use of the Framingham model to help identify those at high risk of developing the disease. However, this model has not been validated for the Indigenous population. Design Cohort study. Methods Framingham models were applied to the Well Person's Health Check (WPHC) cohort (followed 1998-2014), which included 1448 Aboriginal and Torres Strait Islanders from remote Indigenous communities in Far North Queensland...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28748774/exposure-to-parental-psychopathology-and-offspring-s-risk-of-suicide-related-thoughts-and-behaviours-a-systematic-review
#5
S M Goodday, J Shuldiner, S Bondy, A E Rhodes
AIMS: The primary objective of this systematic review was to identify and synthesise analytic studies examining the association between exposure to parental psychopathology in childhood and the nature of subsequent suicide-related thoughts (SRT) and suicide-related behaviour (SRB) (severity of ideation, planned/unplanned attempts/lethality) and to describe the direction, and magnitude of associations. The secondary objective was to determine if the associations from the primary objective differ by the type(s) and timing of parental psychopathology, sex/gender of the parent and child and is mediated by child psychiatric symptoms and family functioning...
July 27, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28748715/rate-of-bleeding-related-episodes-in-elderly-patients-with-primary-immune-thrombocytopenia-a-retrospective-cohort-study
#6
Shuling Li, Julia T Molony, Karynsa Cetin, Jeffrey S Wasser, Ivy Altomare
OBJECTIVE: Immune thrombocytopenia (ITP) is characterized by low platelet counts and a tendency toward increased bleeding and bruising. We aimed to describe bleeding frequency and use of rescue ITP therapy to treat or prevent bleeding in elderly ITP patients in a real-world setting. METHODS: Using Medicare 20% sample data, 2007-2012, we identified elderly (ages ≥67 years) Medicare fee-for-service enrollees diagnosed with primary ITP January 1, 2009-September 30, 2012...
July 27, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28748509/clinical-characteristics-and-thrombosis-outcomes-of-paediatric-antiphospholipid-syndrome-analysis-of-58-patients
#7
Jingran Ma, Hongmei Song, Min Wei, Yanyan He
The study aims to analyse the clinical and immunological manifestations of paediatric antiphospholipid syndrome (APS) in patients, based on the 2006 revised classification criteria of definite APS. Fifty-eight paediatric patients with APS were enrolled and analysed retrospectively. A total of 37 female and 21 male patients with a mean age of 14 ± 3 years at disease onset were included. Fourteen (24%) cases were primary APS, and 40 (69%) cases were secondary to systemic lupus erythaematosus (SLE). Anti-nuclear antibody (ANA) positivity and hypocomplementemia were more common in secondary APS than in primary APS...
July 26, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28748083/lactadherin-orthologs-inhibit-migration-of-human-porcine-and-murine-intestinal-epithelial-cells
#8
Steffen Nyegaard, Trine Andreasen, Jan Trige Rasmussen
Lactadherin was originally described due to its appearance in milk, but is abundantly expressed especially by professional and nonprofessional phagocytes. The proteins has been shown to have a multitude of bioactive effects, including inhibition of inflammatory phospholipases, induction of effero- and phagocytosis, prevent rotavirus induced gastroenteritis, and modulate intestinal homeostasis by regulating epithelial cell migration. The level of expression seems to be important in a row of serious pathologies linked to the intestinal epithelial barrier function, vascular- and autoimmune disease...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28747959/effect-of-prophylactic-use-of-silymarin-on-anti-tuberculosis-drugs-induced-hepatotoxicity
#9
Eunyoung Heo, Deog Kyeom Kim, So Hee Oh, Jung-Kyu Lee, Ju-Hee Park, Hee Soon Chung
BACKGROUND: The first line of anti-tuberculosis (TB) drugs are the most effective standard of drugs for TB. However, the use of these drugs is associated with hepatotoxicity. Silymarin has protective effects against hepatotoxicity of anti-TB drugs in animal models. This study aims to investigate the protective effect of silymarin on hepatotoxicity caused by anti-TB drugs. METHODS: This is a prospective, randomized, double-blind and placebo-controlled study. Patients were eligible if they were 20 years of age or order and started the first-line anti-tuberculosis drugs...
July 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28747839/etiological-evaluation-of-primary-congenital-hypothyroidism-cases
#10
Diğdem Bezen, Emine Dilek, Neşe Torun, Filiz Tütüncüler
AIM: Primary congenital hypothyroidism is frequently seen endocrine disorder and one of the preventable cause of mental retardation. Aim of study was to evaluate the frequency of permanent/transient hypothyrodism, and to detect underlying reason to identfy any marker which carries potential to discriminate permanent/transient form. MATERIAL AND METHODS: Forty eight cases older than 3 years of age, diagnosed as primary congenital hypothyroidism and started thyroxin therapy in newborn-period, and followed up between January 2007-June 2013 were included in the study...
June 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28747516/redundant-and-diverse-intranodal-pacemakers-and-conduction-pathways-protect-the-human-sinoatrial-node-from-failure
#11
Ning Li, Brian J Hansen, Thomas A Csepe, Jichao Zhao, Anthony J Ignozzi, Lidiya V Sul, Stanislav O Zakharkin, Anuradha Kalyanasundaram, Jonathan P Davis, Brandon J Biesiadecki, Ahmet Kilic, Paul M L Janssen, Peter J Mohler, Raul Weiss, John D Hummel, Vadim V Fedorov
The human sinoatrial node (SAN) efficiently maintains heart rhythm even under adverse conditions. However, the specific mechanisms involved in the human SAN's ability to prevent rhythm failure, also referred to as its robustness, are unknown. Challenges exist because the three-dimensional (3D) intramural structure of the human SAN differs from well-studied animal models, and clinical electrode recordings are limited to only surface atrial activation. Hence, to innovate the translational study of human SAN structural and functional robustness, we integrated intramural optical mapping, 3D histology reconstruction, and molecular mapping of the ex vivo human heart...
July 26, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28747511/autologous-minced-muscle-grafts-improve-endogenous-fracture-healing-and-muscle-strength-after-musculoskeletal-trauma
#12
Brady J Hurtgen, Catherine L Ward, Chrissy M Leopold Wager, Koyal Garg, Stephen M Goldman, Beth E P Henderson, Todd O McKinley, Sarah M Greising, Joseph C Wenke, Benjamin T Corona
The deleterious impact of concomitant muscle injury on fracture healing and limb function is commonly considered part of the natural sequela of orthopedic trauma. Recent reports suggest that heightened inflammation in the surrounding traumatized musculature is a primary determinant of fracture healing. Relatedly, there are emerging potential therapeutic approaches for severe muscle trauma (e.g., volumetric muscle loss [VML] injury), such as autologous minced muscle grafts (1 mm(3) pieces of muscle; GRAFT), that can partially prevent chronic functional deficits and appear to have an immunomodulatory effect within VML injured muscle...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28747442/chemotherapy-induced-peripheral-neuropathy-clinical-trials-review-and-recommendations
#13
REVIEW
Jennifer S Gewandter, Roy Freeman, Rachel A Kitt, Guido Cavaletti, Lynn R Gauthier, Michael P McDermott, Nimish A Mohile, Supriya G Mohlie, A Gordon Smith, Mohamedtaki A Tejani, Dennis C Turk, Robert H Dworkin
OBJECTIVE: To assess the design characteristics and reporting quality of published randomized controlled trials (RCTs) for treatments of chemotherapy-induced peripheral neuropathy (CIPN) initiated before or during chemotherapy. METHODS: In this systematic review of RCTs of preventive or symptomatic pharmacologic treatments for CIPN initiated before or during chemotherapy treatment, articles were identified by updating the PubMed search utilized in the CIPN treatment guidelines published in the Journal of Clinical Oncology in 2014...
July 26, 2017: Neurology
https://www.readbyqxmd.com/read/28747313/long-term-complications-reoperations-and-survival-following-cardioverter-defibrillator-implant
#14
Nathaniel Mark Hawkins, Maja Grubisic, Jason G Andrade, Flora Huang, Lillian Ding, Min Gao, Jamil Bashir
OBJECTIVE: Implantable cardioverter-defibrillators (ICDs) reduce risk of death in select populations, but are also associated with harms. We aimed to characterise long-term complications and reoperation rate. METHODS: We assessed the rate, cumulative incidence and predictors of long-term reoperation and survival using a prospective, multicentre registry serving British Columbia in Canada, a universal single payer healthcare system with 4.5 million residents. 3410 patients (mean 63...
July 26, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28747201/intravenous-superoxide-dismutase-as-a-protective-agent-to-prevent-impairment-of-lung-function-induced-by-high-tidal-volume-ventilation
#15
Nan-Chun Wu, Fan-Ting Liao, Hao-Min Cheng, Shih-Hsien Sung, Yu-Chun Yang, Jiun-Jr Wang
BACKGROUND: Positive-pressure mechanical ventilation is essential in assisting patients with respiratory failure in the intensive care unit and facilitating oxygenation in the operating room. However, it was also recognized as a primary factor leading to hospital-acquired pulmonary dysfunction, in which pulmonary oxidative stress and lung inflammation had been known to play important roles. Cu/Zn superoxide dismutase (SOD) is an important antioxidant, and possesses anti-inflammatory capacity...
July 26, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28747193/impact-of-improved-recording-of-work-relatedness-in-primary-care-visits-at-occupational-health-services-on-sickness-absences-study-protocol-for-a-randomised-controlled-trial
#16
Salla Atkins, Ulla Ojajärvi, Nina Talola, Mervi Viljamaa, Jaakko Nevalainen, Jukka Uitti
BACKGROUND: Employment protects and fosters health. Occupational health services, particularly in Finland, have a central role in protecting employee health and preventing work ability problems. However, primary care within occupational health services is currently underused in informing preventive activities. This study was designed to assess whether the recording of work ability problems and improvement of follow-up of work-related primary care visits can reduce sickness absences and work disability pensions after 1 year...
July 26, 2017: Trials
https://www.readbyqxmd.com/read/28747187/general-practitioners-views-and-preferences-about-quality-improvement-feedback-in-preventive-care-a-cross-sectional-study-in-switzerland-and-france
#17
Paul Sebo, Hubert Maisonneuve, Jean-Pascal Fournier, Nicolas Senn, Dagmar M Haller
BACKGROUND: Feedback is widely used as a strategy to improve the quality of care in primary care settings. As part of a study conducted to explore the quality of preventive care, we investigated general practitioners' (GPs) views on the usefulness of feedback and their preferences regarding how feedback is provided. METHODS: This cross-sectional study was conducted in 2015 among randomly selected community-based GPs in two regions of Switzerland and France. GPs were asked to complete an anonymous questionnaire about how often they provided 12 measures of preventive care: blood pressure, weight and height measurements, screening for dyslipidemia, at-risk drinking (and advice to reduce for at-risk drinkers), smoking (and advice to stop for smokers), colon and prostate cancer, and influenza immunization for patients >65 years and at-risk patients...
July 26, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28747160/adverse-events-in-women-and-children-who-have-received-intrapartum-antibiotic-prophylaxis-treatment-a-systematic-review
#18
Farah Seedat, Chris Stinton, Jacoby Patterson, Julia Geppert, Bee Tan, Esther R Robinson, Noel Denis McCarthy, Olalekan A Uthman, Karoline Freeman, Samantha Ann Johnson, Hannah Fraser, Colin Stewart Brown, Aileen Clarke, Sian Taylor-Phillips
BACKGROUND: Adverse events from intrapartum antibiotic prophylaxis (IAP) are poorly documented yet essential to inform clinical practice for neonatal group B Streptococcus (GBS) disease prevention. In this systematic review, we appraised and synthesised the evidence on the adverse events of IAP in the mother and/or her child. METHODS: We searched MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, EMBASE, Cochrane, and Science Citation Index from date of inception until October 16th 2016...
July 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28747027/colchicine-for-prevention-of-post-cardiac-procedure-atrial-fibrillation-meta-analysis-of-randomized-controlled-trials
#19
Mohsin Salih, Aiman Smer, Richard Charnigo, Mohamed Ayan, Yousef H Darrat, Mahmoud Traina, Gustavo X Morales, Luigi DiBiase, Andrea Natale, Claude S Elayi
BACKGROUND: Development of atrial fibrillation after certain cardiac procedures is a common medical problem. The inflammatory process plays an important role in the pathogenesis of post-cardiac procedure atrial fibrillation (PCP-AF). Colchicine, a potent anti-inflammatory agent, has been used in several studies to reduce the risk of PCP-AF. This meta-analysis of randomized controlled trials (RCTs) was conducted to assess the efficacy of colchicine in prevention of PC-PAF. METHODS: We searched PubMed, EMBASE, Web of Science, Cochrane Library database and Google Scholar for RCTs, using terms "Atrial fibrillation, atrial, or fibrillation and colchicine"...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28747026/inferior-and-anterior-qrs-fragmentation-have-different-prognostic-value-in-patients-who-received-an-implantable-defibrillator-in-primary-prevention-of-sudden-cardiac-death
#20
B Vandenberk, T Robyns, G Goovaerts, S Van Soest, V Floré, C Garweg, S Van Huffel, J Ector, R Willems
AIMS: QRS fragmentation (fQRS) has been proposed as a predictor of sudden cardiac death (SCD) and all-cause mortality in ischemic (ICM) and non-ischemic cardiomyopathy patients. However the value of fQRS in patients with a LVEF <35% is a matter of debate. METHODS: All consecutive patients with an indication for an ICD in primary prevention of SCD were included in a retrospective registry from 1996 until 2013. Twelve lead electrocardiograms before implant were analyzed for the presence of fQRS in different regions...
September 15, 2017: International Journal of Cardiology
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