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https://www.readbyqxmd.com/read/29792546/application-of-a-mixture-model-to-assess-the-effect-of-measles-mumps-rubella-vaccine-on-the-mumps-epidemic-in-children-from-kindergarten-to-early-school-age-in-jiangsu-province-china
#1
Lei Zhang, Zhiguo Wang, Ying Hu, Xiuying Deng, Hongxiong Guo, Xiang Sun, Fenyang Tang, Minghao Zhou, Yuanbao Liu
A single dose of the measles-mumps-rubella (MMR) vaccine has been applied in routine immunizations for children in China; however, the Immunoglobulin G (IgG) antibody level of mumps in children from kindergarten to early school age with MMR vaccine immunization history has not been elucidated. This study aimed to describe the immunity profile of children from kindergarten to early school age to identify the susceptible population. In Jiangsu Province, a cross-sectional survey of 4- to 8-year-old children who were vaccinated with at least one dose of MMR vaccine was conducted...
May 24, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29792314/severe-and-predominantly-active-atopic-eczema-in-adulthood-and-long-term-risk-of-cardiovascular-disease-population-based-cohort-study
#2
Richard J Silverwood, Harriet J Forbes, Katrina Abuabara, Anna Ascott, Morten Schmidt, Sigrún A J Schmidt, Liam Smeeth, Sinéad M Langan
OBJECTIVE: To investigate whether adults with atopic eczema are at an increased risk of cardiovascular disease and whether the risk varies by atopic eczema severity and condition activity over time. DESIGN: Population based matched cohort study. SETTING: UK electronic health records from the Clinical Practice Research Datalink, Hospital Episode Statistics, and data from the Office for National Statistics, 1998-2015. PARTICIPANTS: Adults with a diagnosis of atopic eczema, matched (on age, sex, general practice, and calendar time) to up to five patients without atopic eczema...
May 23, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29792224/health-technology-assessment-of-public-health-interventions-an-analysis-of-characteristics-and-comparison-of-methods-study-protocol
#3
Tim Mathes, Gerald Willms, Stephanie Polus, Constance Stegbauer, Melanie Messer, Corinna Klingler, Heidi Ehrenreich, Dea Niebuhr, Georg Marckmann, Ansgar Gerhardus, Dawid Pieper
BACKGROUND: Conducting a health technology assessment (HTA) of public health interventions (PHIs) poses some challenges. PHIs are often complex interventions, which affect the number and degree of interactions of the aspects to be assessed. Randomized controlled trials on PHIs are rare as they are difficult to conduct because of ethical or feasibility issues. The aim of this study is to provide an overview of the methodological characteristics and to compare the applied assessment methods in HTAs on PHIs...
May 23, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29792202/the-effects-of-a-lifestyle-focused-text-messaging-intervention-on-adherence-to-dietary-guideline-recommendations-in-patients-with-coronary-heart-disease-an-analysis-of-the-text-me-study
#4
Karla Santo, Karice Hyun, Laura de Keizer, Aravinda Thiagalingam, Graham S Hillis, John Chalmers, Julie Redfern, Clara K Chow
BACKGROUND: A healthy diet is an important component of secondary prevention of coronary heart disease (CHD). The TEXT ME study was a randomised clinical trial of people with CHD that were randomised into standard care or a text-message programme in addition to standard care. This analysis aimed to: 1) assess the effects of the intervention onadherence to the dietary guideline recommendations; 2) assess the consistency of effect across sub-groups; and 3) assess whether adherence to the dietary guideline recommendations mediated the improvements in objective clinical outcomes...
May 23, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29792125/characteristics-of-apixaban-treated-patients-evaluation-of-the-dose-prescribed-and-the-persistence-of-treatment-a-cohort-study-in-catalonia
#5
Ainhoa Gomez-Lumbreras, Jordi Cortes, Maria Giner-Soriano, M Angeles Quijada-Manuitt, Rosa Morros
BACKGROUND: Apixaban is a direct oral anticoagulant, which inhibits factor Xa. It has demonstrated clinical efficacy in prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation and a better safety profile compared to warfarin. OBJECTIVES: (1) To describe the characteristics of patients with nonvalvular atrial fibrillation beginning treatment with apixaban, (2) to analyze concomitant prescriptions of medications that could potentially interact with apixaban, (3) to evaluate the level of appropriate usage according to the recommended dosage, and (4) to estimate the level of apixaban persistence among naive and non-naive patients...
January 1, 2018: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29792058/utilization-of-progesterone-and-cervical-length-screening-for-prevention-of-recurrent-preterm-birth
#6
Rupsa C Boelig, Eva Jiang, Brooke Scheidemantle, Michela Villani, Vincenzo Berghella
OBJECTIVE: To assess utilization of progesterone and cervical length (CL) screening among women with prior spontaneous preterm birth (sPTB). METHODS: This is a retrospective cohort study of women with prior sPTB. Primary outcomes were the use of progesterone and CL screening. Secondary outcomes were reasons for failure to utilize interventions and factors associated with use of recommended interventions. RESULTS: One hundred and eighty women had a prior sPTB...
May 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29791911/improving-translation-from-preclinical-studies-to-clinical-trials-in-acute-kidney-injury
#7
Marco Fiorentino, John A Kellum
BACKGROUND: Several cellular and molecular targets and mechanisms have been investigated in preclinical studies of acute kidney injury (AKI), but translation in successful clinical studies has failed to date. This article reviews many issues that have limited this and the potential future perspectives in AKI prevention and treatment. SUMMARY: Preclinical models of AKI should closely mimic the complexity of human AKI, considering the importance of several comorbidities in determining the clinical course and outcomes in the human disease...
May 23, 2018: Nephron
https://www.readbyqxmd.com/read/29791794/photolysis-of-mono-and-di-chloramines-in-uv-hydrogen-peroxide-effects-on-1-4-dioxane-removal-and-relevance-in-water-reuse
#8
Samuel Patton, Mariano Romano, Vincenzo Naddeo, Kenneth P Ishida, Haizhou Liu
Growing demands and increasing scarcity of fresh water resources necessitate potable water reuse, which has been implemented with the aid of UV-based advanced oxidation processes (UV/AOPs) that remove potentially hazardous trace organic contaminants from reclaimed water. During the potable reuse treatment process, chloramines are added to prevent membrane fouling that are carried over to the UV/AOP, where hydrogen peroxide (H2O2) is commonly added. However, the impact of chloramines on the photolysis of H2O2 and the overall performance of the UV/AOP remains unknown...
May 23, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29791673/development-of-a-clinical-protocol-for-detection-of-cervical-cancer-precursor-lesions
#9
Deise Maria Do Nascimento Sousa, Ana Carolina Maria Araújo Chagas, Camila Teixeira Moreira Vasconcelos, Airton Tetelbom Stein, Mônica Oliveira Batista Oriá
OBJECTIVE: to develop and validate the content of a clinical protocol aimed at prevention of cervical cancer in primary care. METHOD: technological research according to the steps: (1) submission of the project to the research ethics committee; (2) bibliographic survey; (3) elaboration of the clinical protocol; and (4) content validation. In the third step, the information was collected through bibliographic research and gynecology specialists were consulted. For the final step, four judges were selected to evaluate the clinical protocol according to AGREE 2...
2018: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29791646/repercussions-of-hospitalization-due-to-fall-of-the-elderly-health-care-and-prevention
#10
Adriana Remião Luzardo, Newton Ferreira de Paula Júnior, Marcelo Medeiros, Paula Carolina Bejo Wolkers, Silvia Maria Azevedo Dos Santos
OBJECTIVE: To know the repercussions of the fall reported by the elderly and their caregiver during hospitalization in a public hospital in Florianópolis city from October to December 2014. METHOD: Exploratory research with a qualitative approach, conducted by depth interviews with 16 participants, the eight elderly were hospitalized for falls and eight elderly caregivers. Data analysis were performed through the Thematic Content Analysis. RESULTS: It was evidenced the thematic axis: Faller Elderly supported by four thematic categories: Changes caused by Falls, I am a faller, I take care of me and Prevention of the Fall...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791623/social-representation-of-elderly-people-on-falls-structural-analysis-and-in-the-light-of-neuman
#11
Jéssica de Castro Santos, Cristina Arreguy-Sena, Paulo Ferreira Pinto, Elenir de Paiva Pereira, Marcelo da Silva Alves, Fabiano Bolpato Loures
OBJECTIVE: To understand the symbolic elements and the hierarchical system of representations of elderly people on falls, according to Abric's structural analysis and Neuman's theory. METHOD: Abric structural approach developed at the home of primary care users in a city of Minas Gerais. A free evocation technique of images triggered by images was performed in 2016 with elderly individuals (≥65 years old). Data treated by dictionary of equivalent terms; processed in Evoc 2000 software converging, analytically, according to Neuman...
2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29791465/predictors-of-subclinical-carotid-atherosclerosis-in-middle-aged-women
#12
Isly L de Barros, Laura Costa, Bento Bezerra, Rafael Gomes, Natanael Morais, Célia M C Strunz, Moacir Novaes, Otávio C E Gebara, Rodrigo Pinto Pedrosa, José C Nicolau
BACKGROUND: Traditional strategies for primary cardiovascular prevention have been insufficient in reducing the high rates of coronary ischemic events in women, probably because these women are often stratified into low-risk groups. However, cardiovascular diseases continue to be the main cause of morbidity and mortality in women worldwide. We hypothesized that carotid atherosclerosis (CA) is common in middle-aged women. METHODS: We prospectively evaluated asymptomatic peri- and post-menopausal women with no cardiovascular diseases or the use of hormone therapy from two gynecologic clinics...
2018: PloS One
https://www.readbyqxmd.com/read/29791437/a-randomized-controlled-trial-on-the-effect-of-a-silver-carboxymethylcellulose-dressing-on-surgical-site-infections-after-breast-cancer-surgery
#13
Gerson M Struik, Wietske W Vrijland, Erwin Birnie, Taco M A L Klem
BACKGROUND: The incidence of surgical site infections (SSIs) after breast cancer surgery is relatively high; ranging from 3 to 19%. The role of wound dressings in the prevention of SSI after breast cancer surgery is unclear. This study compares a silver carboxymethylcellulose dressing (AQUACEL Ag Surgical (Aquacel) with standard wound dressing in SSI rate after breast cancer surgery. PATIENTS AND METHODS: A single-centre randomized controlled trial among women ≥18 years, diagnosed with breast cancer, undergoing breast conserving or ablative surgery, was conducted in a combined in and outpatient setting...
2018: PloS One
https://www.readbyqxmd.com/read/29791276/isolating-the-association-of-sleep-depressive-state-and-other-independent-indicators-for-suicide-ideation-in-united-states-teenagers
#14
Lynn M Whitmore, Tyler C Smith
According to the Centers for Disease Control and Prevention, suicide is the second leading cause of death in American teenagers, and is a growing public health concern. This study uses multivariable logistic regression to investigate the independent relationship between suicide ideation and sleep duration in teenagers using the 2015 Youth Behavior Risk Surveillance Study, controlling for demographic, behavioral, and other factors found to be associated. Sleep durations of 4-5 hours and 6-7 hours per night were associated with approximately 75-80% and 20-40% increased adjusted odds of suicide ideation, as compared to teens sleeping the recommended 8 hours or more, and should be considered as a potential important indicator for adolescent suicidal ideation in in primary-care screens...
May 23, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/29791244/the-need-for-mapping-personal-goals-to-exercise-dosage-in-community-based-exercise-programs-for-people-with-parkinson-s-disease
#15
Allison L Amateis, Chelsea L Boesel, Bryan P Ehnert, Abby S Evans, Katheryn E Hurst, Katie L Marek, Amanda C Sullivan, Kathryn R Zalewski, Wendy E Huddleston
PURPOSE: Community-based exercise can support long-term management of Parkinson's disease, although it is not known if personal goals are met in these programs. The objectives of this study were to: (1) examine the goals of community based exercise programs from the participant and instructor perspectives; (2) establish the extent to which these programs meet self-described exercise outcomes; and (3) explore participant and instructor perspectives on barriers to meeting exercise expectations...
May 23, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29790923/missed-opportunities-to-prescribe-preexposure-prophylaxis-in-south-carolina-2013-2016
#16
Dawn K Smith, Man-Huei Chang, Wayne A Duffus, Stella Okoye, Sharon Weissman
Introduction: Expanding use of preexposure prophylaxis (PrEP) in ways that address current racial/ethnic disparities is an important HIV prevention goal. We investigated missed opportunities to provide PrEP during healthcare visits occurring prior to HIV infection. Methods: This retrospective cohort study linked South Carolina HIV case surveillance data to 3 statewide healthcare databases. Characteristics of patients, health care visits and providers, sexually transmitted diseases (STD), and other diagnoses, were assessed for medical encounters occurring before an initial HIV diagnosis...
May 22, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29790727/pathophysiology-of-severe-traumatic-brain-injury-overview
#17
Ruth A O'leary, Alistair D Nichol
Traumatic brain injury is a leading cause of morbidity and mortality globally, particularly among young people, with significant social and economic effects. The World Health Organization (WHO) estimates that more than five million people die each year from traumatic injuries worldwide. While public health initiative such as seatbelts and airbags have had a major impact, it will be impossible to prevent traumatic brain injury, it is therefore that we understand the pathophysiology of secondary brain injury to be able to effectively treat our patient but aloes to develop novel targets of future interventions...
May 22, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29790571/-epidemiology-of-alzheimer-s-disease-and-other-dementias
#18
REVIEW
J Garre-Olmo
INTRODUCTION: Dementia is a clinical syndrome resulting from a number of causations and which is usually accompanied by progressive and diffuse brain dysfunction. The different subtypes are characterised by a clinical picture with common symptoms that differ in terms of their aetiology, age, clinical presentation, clinical course and associated disorders. AIM: To present an update on the information available about the descriptive epidemiology of dementia and its main subtypes...
June 1, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29790552/quantum-dot-polymer-conjugates-for-stable-luminescent-displays
#19
Sushant Ghimire, Anjali Sivadas, Ken-Ichi Yuyama, Yuta Takano, Raju Francis, Vasudevanpillai Biju
The broad absorption of light in the UV-Vis-NIR region and the size-based tunable photoluminescence color of semiconductor quantum dots make these tiny crystals one of the most attractive antennae in solar cells and phosphors in electrooptical devices. One of the primary requirements for such real-world applications of quantum dots is their stable and uniform distribution in optically transparent matrices. In this work, we prepare transparent thin films of polymer-quantum dot conjugates, where CdSe/ZnS quantum dots are uniformly distributed at high densities in a chitosan-polystyrene copolymer (CS-g-PS) matrix...
May 23, 2018: Nanoscale
https://www.readbyqxmd.com/read/29790202/incidence-and-cost-of-medication-harm-in-older-adults-following-hospital-discharge-a-multicentre-prospective-study-in-the-uk
#20
Nikesh Parekh, Khalid Ali, Jennifer M Stevenson, J Graham Davies, Rebekah Schiff, Tischa Van der Cammen, Jatinder Harchowal, James Raftery, Chakravarthi Rajkumar
AIMS: Polypharmacy is increasingly common in older adults, placing them at risk of medication-related harm (MRH). Patients are particularly vulnerable to problems with their medications in the period following hospital discharge due to medication changes, and poor information transfer between hospital and primary care. The aim of this study was to investigate the incidence, severity, preventability and cost of medication-related harm (MRH) in older adults in England post-discharge. METHODS: An observational multicentre prospective cohort study recruited 1280 older adults (median age 82 years) from five teaching hospitals in Southern England, UK...
May 22, 2018: British Journal of Clinical Pharmacology
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