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https://www.readbyqxmd.com/read/28454393/diagnosing-and-discriminating-between-primary-and-secondary-aneurysmal-bone-cysts
#1
Hiromi Sasaki, Satoshi Nagano, Hirofumi Shimada, Masahiro Yokouchi, Takao Setoguchi, Yasuhiro Ishidou, Osamu Kunigou, Kosuke Maehara, Setsuro Komiya
Aneurysmal bone cysts (ABCs) are benign bony lesions frequently accompanied by multiple cystic lesions and aggressive bone destruction. They are relatively rare lesions, representing only 1% of bone tumors. The pathogenesis of ABCs has yet to be elucidated. In the present study, a series of 22 cases of primary and secondary ABC from patients treated in Department of Orthopedic Surgery, Kagoshima University Hospital (Kagoshima, Japan) from 2001-2015 were retrospectively analyzed. The average age at the time of diagnosis of primary ABC was 17...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28453969/reducing-intrusive-traumatic-memories-after-emergency-caesarean-section-a-proof-of-principle-randomized-controlled-study
#2
Antje Horsch, Yvan Vial, Céline Favrod, Mathilde Morisod Harari, Simon E Blackwell, Peter Watson, Lalitha Iyadurai, Michael B Bonsall, Emily A Holmes
Preventative psychological interventions to aid women after traumatic childbirth are needed. This proof-of-principle randomized controlled study evaluated whether the number of intrusive traumatic memories mothers experience after emergency caesarean section (ECS) could be reduced by a brief cognitive intervention. 56 women after ECS were randomized to one of two parallel groups in a 1:1 ratio: intervention (usual care plus cognitive task procedure) or control (usual care). The intervention group engaged in a visuospatial task (computer-game 'Tetris' via a handheld gaming device) for 15 min within six hours following their ECS...
April 6, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28453947/a-secondary-analysis-of-mistreatment-of-women-during-childbirth-in-health-care-facilities
#3
Cheryl Tatano Beck
OBJECTIVE: To conduct a secondary qualitative analysis of a phenomenological study of traumatic childbirth to identify the types and frequency of mistreatment of women during childbirth in high-income countries. DESIGN: Analytic expansion was the type of secondary analysis chosen to make further use of a primary qualitative data set to ask a new question that was not included the original study aims. SETTING: The primary data set of women's experiences of traumatic childbirth was obtained via the Internet...
April 25, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28453826/unplanned-readmissions-within-30-days-after-discharge-improving-quality-through-easy-prediction
#4
Francesca Casalini, Susanna Salvetti, Silvia Memmini, Elena Lucaccini, Gabriele Massimetti, Pier Luigi Lopalco, Gaetano Pierpaolo Privitera
Objective: To propose an easy predictive model for the risk of rehospitalization, built from hospital administrative data, in order to prevent repeated admissions and to improve transitional care. Design: Retrospective cohort study. Setting: Azienda Ospedaliero Universitaria Pisana (Pisa University Hospital). Participants: Patients residing in the territory of the province of Pisa (Tuscany Region) with at least one unplanned hospital admission leading to a medical Diagnosis-Related Group (DRG) in the calendar year 2012...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453648/recent-advances-in-sequence-assembly-principles-and-applications
#5
Qingfeng Chen, Chaowang Lan, Liang Zhao, Jianxin Wang, Baoshan Chen, Yi-Ping Phoebe Chen
The application of advanced sequencing technologies and the rapid growth of various sequence data have led to increasing interest in DNA sequence assembly. However, repeats and polymorphism occur frequently in genomes, and each of these has different impacts on assembly. Further, many new applications for sequencing, such as metagenomics regarding multiple species, have emerged in recent years. These not only give rise to higher complexity but also prevent short-read assembly in an efficient way. This article reviews the theoretical foundations that underlie current mapping-based assembly and de novo-based assembly, and highlights the key issues and feasible solutions that need to be considered...
April 26, 2017: Briefings in Functional Genomics
https://www.readbyqxmd.com/read/28453484/can-better-management-of-periodontal-disease-delay-the-onset-and-progression-of-alzheimer-s-disease
#6
Alice Harding, Sarita Robinson, St John Crean, Sim K Singhrao
A risk factor relationship exists between periodontal disease and Alzheimer's disease (AD) via tooth loss, and improved memory following dental intervention. This links the microbial contribution from indigenous oral periodontal pathogens to the manifestation of chronic conditions, such as AD. Here, we use Porphyromonas gingivalis infection to illustrate its effect on mental health. P. gingivalis infection, in its primary sub-gingival niche, can cause polymicrobial synergy and dysbiosis. Dysbiosis describes the residency of select commensals from the oral cavity following co-aggregation around the dominant keystone pathogen, such as P...
April 25, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28453480/a-multifunctional-biocompatible-drug-candidate-is-highly-effective-in-delaying-pathological-signs-of-alzheimer-s-disease-in-5xfad-mice
#7
Hadar Segal-Gavish, Ortal Danino, Yael Barhum, Tali Ben-Zur, Ella Shai, David Varon, Daniel Offen, Bilha Fischer
BACKGROUND: Metal-ion-chelation was suggested to prevent zinc and copper ions-induced amyloid-β (Aβ) aggregation and oxidative stress, both implicated in the pathophysiology of Alzheimer's disease (AD). In a quest for biocompatible metal-ion chelators potentially useful for AD therapy, we previously tested a series of nucleoside 5'-phosphorothioate derivatives as agents for decomposition of Cu(I)/Cu(II)/Zn(II)-Aβ-aggregates, and as inhibitors of OH radicals formation in Cu(I) or Fe(II) /H2O2 solution...
April 28, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28453475/modifiable-risk-factors-for-prevention-of%C3%A2-dementia-in-midlife-late-life-and-the-oldest-old-validation-of-the-libra-index
#8
Stephanie J B Vos, Martin P J van Boxtel, Olga J G Schiepers, Kay Deckers, Marjolein de Vugt, Isabelle Carrière, Jean-François Dartigues, Karine Peres, Sylvaine Artero, Karen Ritchie, Lucia Galluzzo, Emanuele Scafato, Giovanni B Frisoni, Martijn Huisman, Hannie C Comijs, Simona F Sacuiu, Ingmar Skoog, Kate Irving, Catherine A O'Donnell, Frans R J Verhey, Pieter Jelle Visser, Sebastian Köhler
BACKGROUND: Recently, the LIfestyle for BRAin health (LIBRA) index was developed to assess an individual's prevention potential for dementia. OBJECTIVE: We investigated the predictive validity of the LIBRA index for incident dementia in midlife, late life, and the oldest-old. METHODS: 9,387 non-demented individuals were recruited from the European population-based DESCRIPA study. An individual's LIBRA index was calculated solely based on modifiable risk factors: depression, diabetes, physical activity, hypertension, obesity, smoking, hypercholesterolemia, coronary heart disease, and mild/moderate alcohol use...
April 28, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28453448/cumulative-trauma-disorders-a-review
#9
Zaheen A Iqbal, Ahmad H Alghadir
BACKGROUND: Cumulative trauma disorder (CTD) is a term for various injuries of the musculoskeletal and nervous systems that are caused by repetitive tasks, forceful exertions, vibrations, mechanical compression or sustained postures. Although there are many studies citing incidence of CTDs, there are fewer articles about its etiology, pathology and management. OBJECTIVE: The aim of our study was to discuss the etiology, pathogenesis, prevention and management of CTDs...
April 21, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28453445/the-effectiveness-of-a-cognitive-behavioral-exercise-approach-cbea-compared-to-usual-care-in-patients-with-a-whiplash-associated-disorder-a-quasi-experimental-clinical-trial
#10
Jorge Hugo Villafañe, Davide Perucchini, Joshua A Cleland, Cristina Barbieri, Fernanda de Lima E Sá Resende, Stefano Negrini
BACKGROUND: Whiplash Associated Disorders (WAD) is a biopsychosocial problem, education may be an essential part in the treatment and the prevention of chronic WAD. However, it is still unclear which type of educative intervention has already been used in WAD patients and how effective such interventions are. OBJECTIVE: To examine the effectiveness of a cognitive behavioral exercises approach (CBEA) for self-training of the neck relative to usual care in individuals with WAD in acute phase...
April 21, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28449490/transcutaneous-electrical-acupoint-stimulation-teas-ameliorates-chemotherapy-induced-bone-marrow-suppression-in-lung-cancer-patients
#11
Lili Hou, Fen Gu, Guanghui Gao, Caicun Zhou
BACKGROUND: To investigate the effect of percutaneous electrical stimulation on chemotherapy-induced bone marrow suppression in patients with lung cancer. METHODS: From December 2014 to August 2015, one hundred ninety-one non-small cell lung cancer patients with chemotherapy naive were randomly divided into control group, medication group, and transcutaneous electrical acupoint stimulation (TEAS) group. Patients with the control group received routine nursing care, the medication group was treated by oral administration of prophylactic agents, and TEAS group received electrical stimulation of acupoints including Dazhui (DU14), Geshu (BL17), Zusanli (ST36), Sanyinjiao (SP6), and Hegu (LI4)...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449387/sustaining-nurse-led-task-shifting-strategies-for-hypertension-control-a-concept-mapping-study-to-inform-evidence-based-practice
#12
Sarah Blackstone, Juliet Iwelunmor, Jacob Plange-Rhule, Joyce Gyamfi, Nana Kofi Quakyi, Micheal Ntim, Gbenga Ogedegbe
BACKGROUND: The use of task-shifting is an increasingly widespread delivery approach for health interventions targeting prevention, treatment, and control of hypertension in adults living in sub-Saharan Africa (SSA). Addressing a gap in the literature, this research examined the sustainability of an ongoing task-shifting strategy for hypertension (TASSH) from the perspectives of community health nurses (CHNs) implementing the program. METHODS: We used concept-mapping, a mixed-methods participatory approach to understand CHNs' perceptions of barriers and enablers to sustaining a task-shifting program...
April 27, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28448780/integration-strategies-of-pharmacists-in-primary-care-based-accountable-care-organizations-a-report-from-the-accountable-care-organization-research-network-services-and-education
#13
Tina Joseph, Genevieve M Hale, Sara M Eltaki, Yesenia Prados, Renee Jones, Matthew J Seamon, Cynthia Moreau, Stephanie A Gernant
BACKGROUND: The accountable care organization (ACO) is an innovative health care delivery model centered on value-based care. ACOs consisting of primary care providers are increasingly becoming commonplace in practice; however, medication management remains suboptimal. PROGRAM DESCRIPTION: As experts in medication management, pharmacists perform direct patient care and assist in the transition from one provider to another, which places them in an ideal position to manage multiple aspects of patient care...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448768/toxicity-identification-and-evaluation-tie-of-a-petroleum-refinery-wastewater
#14
Sarah D A Daflon, Igor L Guerra, Márcia V Reynier, Ana C Cerqueira, Clarice R Botta, Juacyara C Campos
Petroleum refineries generate large amounts of wastewaters, which can have acute/chronic toxicity toward aquatic organisms. Previous studies have shown that many contaminants can be responsible for this toxicity, among them ammonia, sulfide, cyanide, phenols and hydrocarbons. In the study reported herein, the cause of the chronic toxicity of a biotreated petroleum refinery wastewater was investigated by applying the TIE methodology using the microcrustacean Ceriodaphnia dubia. Five samples were analyzed, and the results suggest that copper is the primary toxicant, showing a strong correlation with wastewater toxicity in Phase III...
April 27, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28448754/clinical-evaluation-of-cost-efficacy-of-drugs-for-treatment-of-osteoporosis-a-meta-analysis
#15
Stewart G Albert, Supraja Reddy
OBJECTIVE: To assess the cost efficacy of available regimens for therapy of osteoporosis as defined as the cost time's number need to treat to prevent one fracture. PATIENTS AND METHODS: Existing meta-analyses were supplemented through electronic databases SCOPUS and PubMED between 2013 (a date overlapping the latest meta-analyses) and March 2016. Primary references included all randomized controlled trials of anti-osteoporotic drugs versus comparators using search terms "osteoporosis", "random" and "trial"...
April 27, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28448570/disease-burden-for-patients-with-primary-immunodeficiency-diseases-identified-at-reference-hospitals-in-guanajuato-mexico
#16
Eduardo Guaní-Guerra, Ana Isabel Jiménez-Romero, Ulises Noel García-Ramírez, José Manuel Velázquez-Ávalos, Edgar Martínez-Guzmán, Eunice Sandoval-Ramírez, Ignacio Camacho-Meza
BACKGROUND: In addition to the deleterious effect on health, there is considerable economic and psychosocial morbidity associated with primary immunodeficiency diseases (PID). Also, the cost of a late diagnosis frequently results in a heavy disease burden on the patient. The objective of this study was to collect and analyze data on patients with PID in the state of Guanajuato in Mexico, to indirectly estimate the burden of the disease. METHODS: An observational, longitudinal, and comparative study was conducted...
2017: PloS One
https://www.readbyqxmd.com/read/28448523/semaphorin-1a-prevents-drosophila-olfactory-projection-neuron-dendrites-from-mis-targeting-into-select-antennal-lobe-regions
#17
Hung-Chang Shen, Sao-Yu Chu, Tsai-Chi Hsu, Chun-Han Wang, I-Ya Lin, Hung-Hsiang Yu
Elucidating how appropriate neurite patterns are generated in neurons of the olfactory system is crucial for comprehending the construction of the olfactory map. In the Drosophila olfactory system, projection neurons (PNs), primarily derived from four neural stem cells (called neuroblasts), populate their cell bodies surrounding to and distribute their dendrites in distinct but overlapping patterns within the primary olfactory center of the brain, the antennal lobe (AL). However, it remains unclear whether the same molecular mechanisms are employed to generate the appropriate dendritic patterns in discrete AL glomeruli among PNs produced from different neuroblasts...
April 27, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28448327/community-osteoporosis-screening-services-for-the-prevention-of-osteoporotic-fractures-in-population-health-a-literature-review
#18
Vu H Nguyen
AIM: To determine the implications of the reviewed literature in population health improvement. METHOD: A review of the literature was conducted with the search of four databases: PubMed, PsycINFO, ERIC, and Google Scholar. Search terms entered into these databases were 'osteoporosis community'. After a thorough review of all search results, 11 studies were found to be community osteoporosis screening services, and descriptions of each study's participants and location, details and descriptions of each study's community osteoporosis screening service, and effectiveness on outcome measure(s) for each study's objective were reviewed and examined to determine their implications on population health...
April 26, 2017: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/28448203/systematic-review-and-meta-analysis-of-randomized-controlled-trials-evaluating-prophylactic-intra-operative-wound-irrigation-for-the-prevention-of-surgical-site-infections
#19
Stijn W de Jonge, Quirine J J Boldingh, Joseph S Solomkin, Benedetta Allegranzi, Matthias Egger, E Patchen Dellinger, Marja A Boermeester
BACKGROUND: Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI prevention guidelines, a systematic literature review and a meta-analysis were conducted on the effectiveness of pIOWI using different agents as a means of reducing SSI. METHODS: The PUBMED, Embase, CENTRAL, CINAHL, and WHO databases were searched...
April 27, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28447973/methods-to-study-lipid-alterations-in-neutrophils-and-the-subsequent-formation-of-neutrophil-extracellular-traps
#20
Graham Brogden, Ariane Neumann, Diab M Husein, Friederike Reuner, Hassan Y Naim, Maren von Köckritz-Blickwede
Lipid analysis performed by high performance thin layer chromatography (HPTLC) is a relatively simple, cost-effective method of analyzing a broad range of lipids. The function of lipids (e.g., in host-pathogen interactions or host entry) has been reported to play a crucial role in cellular processes. Here, we show a method to determine lipid composition, with a focus on the cholesterol level of primary blood-derived neutrophils, by HPTLC in comparison to high performance liquid chromatography (HPLC). The aim was to investigate the role of lipid/cholesterol alterations in the formation of neutrophil extracellular traps (NETs)...
March 29, 2017: Journal of Visualized Experiments: JoVE
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