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https://www.readbyqxmd.com/read/28087551/cost-effectiveness-of-superficial-femoral-artery-endovascular-interventions-in-the-uk-and-germany-a-modelling-study
#1
Benjamin C Kearns, Steven M Thomas
OBJECTIVES: To assess the lifetime costs and cost-effectiveness of 5 endovascular interventions to treat superficial femoral arterial disease. DESIGN: A model-based health economic evaluation. An existing decision analytical model was used, with updated effectiveness data taken from the literature, and updated costs based on purchasing prices. SETTING: UK and German healthcare perspectives were considered. PARTICIPANTS: Patients with intermittent claudication of the femoropopliteal arteries eligible for endovascular treatment...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28081585/drug-eluting-stent-placement-versus-coronary-artery-bypass-surgery-for-unprotected-left-main-coronary-artery-disease-a-meta-analysis-of-randomized-controlled-trials
#2
Sunil Upadhaya, Ramkaji Baniya, Seetharamprasad Madala, Suresh Kumar Subedi, Jahangir Khan, Ravi Kanth Velagapudi, Ghassan Bachuwa
BACKGROUND: Coronary artery bypass grafting (CABG) is the standard of care for treating left main coronary lesions. However, recently published randomized controlled trials (RCT) have shown conflicting results. We sought to compare clinical outcomes of percutaneous coronary intervention (PCI) with drug-eluting stent placement to CABG using a meta-analysis of randomized controlled trials. METHODS: A systemic search of Pubmed, Scopus, Cochrane library, and Clinicaltrials...
January 12, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28079127/functional-nanoarchitectures-for-enhanced-drug-eluting-stents
#3
Yomna E Saleh, Mohamed A Gepreel, Nageh K Allam
Different strategies have been investigated to allow for optimum duration and conditions for endothelium healing through the enhancement of coronary stents. In this study, a nanoarchitectured system is proposed as a surface modification for drug eluting stents. Highly oriented nanotubes were vertically grown on the surface of a new Ni-free biocompatible Ti-based alloy, as a potential material for self-expandable stents. The fabricated nanotubes were self-grown from the potential stent substrate, which are also proposed to enhance endothelial proliferation while acting as drug reservoir to hinder Vascular Smooth Muscle Cells (VSMC) proliferation...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28073668/drug-eluting-stenting-for-femoropopliteal-lesions-followed-by-cilostazol-treatment-reduces-stent-restenosis-in-patients-with-symptomatic-peripheral-artery-disease
#4
Kan Zen, Mitsuyoshi Takahara, Osamu Iida, Yoshimitsu Soga, Daizo Kawasaki, Shinsuke Nanto, Hiroyoshi Yokoi, Satoaki Matoba
BACKGROUND: Cilostazol improves clinical endovascular therapy outcomes for femoropopliteal (FP) lesions in patients with symptomatic peripheral arterial disease, but whether it also has clinical benefits for patients after drug-eluting stent implantation remains unclear. METHODS: This study is a subanalysis of the ZilvEr PTX for tHe Femoral ArterY and Proximal Popliteal ArteRy (ZEPHYR) study, a prospective multicenter study investigating FP lesions treated with the Zilver (Cook Medical, Bloomington, Ind) paclitaxel-eluting stent...
January 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28073430/outcomes-of-first-versus-second-generation-drug-eluting-stent-implanted-for-right-coronary-artery-ostial%C3%A2-narrowing
#5
Ryuta Sugihara, Yasunori Ueda, Yuji Nishimoto, Kuniaki Takahashi, Ayaka Murakami, Keisuke Ueno, Yasuharu Takeda, Akio Hirata, Kazunori Kashiwase, Yoshiharu Higuchi, Yoshio Yasumura
Clinical outcome is generally poor when stents are implanted at right coronary artery ostial lesion (RCAos). We compared the clinical outcome between the first-generation drug-eluting stent (first DES) and second-generation drug-eluting stent (second DES) used for RCAos. Consecutive 88 patients who underwent percutaneous coronary interventions of de novo RCAos using the first DES (33 patients) or second DES (55 patients) were analyzed. The incidence of major adverse cardiac events (MACE) defined as the composite of cardiac death, myocardial infarction attributed to right coronary artery, and target lesion revascularization within 2...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28072714/optical-coherence-tomography-assessment-of-a-complex-bifurcation-lesion-treated-with-double-kissing-crush-technique-a-case-report
#6
Jin-Zan Cai, Yao-Jun Zhang, Tian Xu, Yong-Xiang Zhu, Chen-Yu Mao, Christos V Bourantas, Tom Crake, Shao-Liang Chen
The DEFINITION (Impact of the complexity of bifurcation lesions treated with drug-eluting stents) study has provided a novel classification to evaluate the complexity of coronary bifurcation lesion according to coronary angiography, but angiographic imaging due to its low resolution and inherited limitation may result in an inaccurate adjudication.We used optical coherence tomography (OCT) to further evaluate the coronary characteristics in a patient with "simple" bifurcation lesion which was classified by the DEFINITION criteria...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28069015/impact-of-smoking-on-health-related-quality-of-life-after-percutaneous-coronary-intervention-treated-with-drug-eluting-stents-a-longitudinal-observational-study
#7
Chao Xue, Lin Bian, Yu Shui Xie, Zhao Fang Yin, Zuo Jun Xu, Qi Zhi Chen, Hui Li Zhang, Chang Qian Wang
BACKGROUND: Smoking has been shown to reduce health-related quality of life (HRQOL) in patients with coronary artery disease (CAD) undergoing percutanous coronary intervention (PCI) either by means of balloon angioplasty or with the use of bare-metal stents (BMS). Drug-eluting stents (DES) have now been widely used and are related to substantial reduction of restenosis and significantly improved HRQOL compared with BMS. This study aimed to evaluate the effects of smoking on HRQOL in patients after PCI in DES era...
January 3, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28067198/outcomes-of-patients-treated-with-durable-polymer-platinum-chromium-everolimus-eluting-stents-a-meta-analysis-of-randomized-trials
#8
Salvatore Cassese, Gjin Ndrepepa, Robert A Byrne, Sebastian Kufner, Erion Xhepa, Antoinette de Waha, Tobias Rheude, Roisin Colleran, Daniele Giacoppo, Yukinori Harada, Karl-Ludwig Laugwitz, Heribert Schunkert, Massimiliano Fusaro, Adnan Kastrati
AIMS: The durable-polymer platinum-chromium everolimus-eluting stent (PtCr-EES) is a new- generation drug-eluting stent (DES) with a platinum-enriched metallic platform developed to improve the percutaneous treatment of patients with coronary artery disease. We sought to investigate the performance of durable-polymer PtCr-EES versus other new-generation DES. METHODS AND RESULTS: We undertook a meta-analysis of trials, in which patients receiving percutaneous coronary intervention (PCI) were randomly assigned to durable-polymer PtCr-EES versus other new-generation DES (other DES)...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28066576/to-complete-or-not-to-complete-that-is-the-question-of-revascularization-in-percutaneous-coronary-intervention-with-drug-eluting-stents-for-multivessel-disease
#9
EDITORIAL
Hisato Takagi, Tomo Ando, Takuya Umemoto
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28065691/difference-in-vascular-response-between-sirolimus-eluting-and-everolimus-eluting-stents-in-ostial-left-circumflex-artery-after-unprotected-left-main-as-observed-by-optical-coherence-tomography
#10
Yusuke Fujino, Guilherme F Attizzani, Satoko Tahara, Toru Naganuma, Kensuke Takagi, Hiroto Yabushita, Wei Wang, Kentaro Tanaka, Takahiro Matsumoto, Hiroyoshi Kawamoto, Yuya Yamada, Shinnosuke Amano, Yusuke Watanabe, Takayuki Warisawa, Tomohiko Sato, Satoru Mitomo, Naoyuki Kurita, Hisaaki Ishiguro, Koji Hozawa, Takahiro Tsukahara, Masahiro Motosuke, Hiram G Bezerra, Shotaro Nakamura, Sunao Nakamura
BACKGROUND: Kissing-balloon technique (KBT) is commonly performed during percutaneous coronary intervention of distal unprotected left main coronary artery (ULM) aiming at obtaining optimal opening of the side branch (left circumflex artery; LCX) ostium. Nonetheless, detailed evaluation of vascular response to stents in LCX ostium is lacking. We therefore evaluated the vascular response to different drug-eluting stents (DES) in ostial LCX after ULM by means of optical coherence tomography (OCT)...
December 23, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28062139/efficacy-and-safety-of-everolimus-and-zotarolimus-eluting-stents-versus-first-generation-drug-eluting-stents-in-patients-with-diabetes-a-meta-analysis-of-randomized-trials
#11
Chirag Bavishi, Usman Baber, Sadik Panwar, Stefania Pirrotta, George D Dangas, Pedro Moreno, Jacqueline Tamis-Holland, Annapoorna S Kini, Samin K Sharma
INTRODUCTION: Patients with diabetes and coronary artery disease remain at high risk for adverse cardiovascular events after percutaneous coronary intervention. The efficacy and safety of the various drug-eluting stents (DES) in patients with diabetes is unclear. METHODS: Randomized controlled trials comparing first-generation DES [paclitaxel-eluting stents (PES) and sirolimus-eluting stents (SES)] with everolimus-eluting stents (EES) and zotarolimus-eluting stents (ZES) in diabetic patients were systematically searched...
December 27, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28061808/effect-of-diabetes-mellitus-on-long-term-outcomes-after-repeat-drug-eluting-stent-implantation-for-in-stent-restenosis
#12
Lin Zhao, Weiwei Zhu, Xiaojiang Zhang, Dongfang He, Chengjun Guo
BACKGROUND: Whether diabetes mellitus (DM) is a predictor of long-term adverse clinical outcomes after repeat drug eluting stent (DES) implantation for DES in-stent restenosis (ISR) remains controversial. We sought to evaluate the effect of DM on the long-term clinical outcomes in patients undergoing repeat DES implantation for DES-ISR lesions. METHODS: In the present study, 254 patients with DES-ISR were divided into DM or non-DM groups according to the presence or absence of DM...
January 6, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28058211/organ-transplantation-and-drug-eluting-stents-perioperative-challenges
#13
REVIEW
Aparna Dalal
Patients listed for organ transplant frequently have severe coronary artery disease (CAD), which may be treated with drug eluting stents (DES). Everolimus and zotarolimus eluting stents are commonly used. Newer generation biolimus and novolimus eluting biodegradable stents are becoming increasingly popular. Patients undergoing transplant surgery soon after the placement of DES are at increased risk of stent thrombosis (ST) in the perioperative period. Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor such as clopidogrel, prasugrel and ticagrelor is instated post stenting to decrease the incident of ST...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28057284/very-late-scaffold-thrombosis-of-bioresorbable-vascular-scaffold-systematic-review-and%C3%A2-a%C3%A2-meta-analysis
#14
Toshiaki Toyota, Takeshi Morimoto, Hiroki Shiomi, Yusuke Yoshikawa, Hidenori Yaku, Yugo Yamashita, Takeshi Kimura
OBJECTIVES: This study sought to compare the 2-year outcomes between bioresorbable vascular scaffold (BVS) and everolimus-eluting metallic drug-eluting stent (EES). BACKGROUND: The occurrence of very late stent/scaffold thrombosis (VLST) of BVS beyond 1 year after implantation is an increasing concern. METHODS: We conducted a meta-analysis of 24 studies (BVS: n = 2,567 and EES: n = 19,806) reporting the 2-year outcomes of BVS and/or EES to compare the risk of BVS versus EES for stent/scaffold thrombosis (ST) and target lesion failure (TLF) in 7 comparative studies (3 randomized and 4 observational), and to estimate the pooled incidence rates of ST and TLF including additional 17 single-arm studies...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28056791/ticagrelor-induced-systemic-inflammatory-response-syndrome
#15
Philipp Krisai, Manuel Haschke, Peter T Buser, Christian Mueller
BACKGROUND: Ticagrelor is a reversible and direct-acting oral antagonist of the adenosine diphosphate receptor P2Y12. Possible adenosine-mediated effects of ticagrelor on inflammation are complex and incompletely understood. To our knowledge, ticagrelor-induced systemic inflammatory response syndrome (SIRS) has not yet been described. CASE PRESENTATION: We report the case of an 84 years old patient presenting with SIRS subsequent to initiation of ticagrelor after implantation of two drug eluting stents...
January 6, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28054461/comparative-efficacy-of-sirolimus-eluting-stents-and-paclitaxel-eluting-stents-in-east-asian-versus-non-east-asian-patients-a-systematic-review-meta-analysis
#16
Rui Zhao, Qianwei Lu, Rui Yang, Jianlin Du, Songbo Deng, Qiang She
BACKGROUND: First-generation drug-eluting stents - such as the sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) - have become attractive options for percutaneous coronary intervention (PCI) and are still widely used in Asia. However, the effect of East Asian ethnicity on their efficacy remains unclear. METHODS: Pubmed, EMBASE, and the Cochrane Central Register of Controlled Trials were searched for randomized controlled trials comparing the efficacy of the Cypher SES and Taxus PES...
January 5, 2017: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/28049984/clinical-outcomes-in-diabetic-patients-who-underwent-percutaneous-coronary-intervention-during-the-plain-old-balloon-angioplasty-poba-bare-metal-stents-bms-and-drug-eluting-stents-des-eras-from-1984-to-2010
#17
Ryo Naito, Katsumi Miyauchi, Hirokazu Konishi, Shuta Tsuboi, Manabu Ogita, Tomotaka Dohi, Takatoshi Kasai, Hiroshi Tamura, Shinya Okazaki, Kikuo Isoda, Hiroyuki Daida
Objective Diabetes is a negative predictor in coronary artery disease patients. Since the introduction of percutaneous coronary intervention (PCI), PCI has evolved through technological advances in devices, improvements in operators' techniques and the establishment of effective therapeutic protocols. The aim of this study is to examine the changes in the clinical outcomes following PCI in patients with diabetes. Methods We compared the clinical outcomes in patients with diabetes following PCI from 1984 to 2010 at Juntendo University over three eras (plain old balloon angioplasty (POBA)-, bare metal stents (BMS)- and drug-eluting stents (DES)-eras)...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28045410/clinical-and-angiographic-outcomes-at-more-than-1-year-after-treatment-of-chronic-total-occlusions-with-the-everolimus-eluting-bioresorbable-vascular-scaffold
#18
Aylin Hatice Yamaç, Abdülkadir Yıldız, Meherrem Nasifov, Ahmet Taştan, Nemat Bashirov, Ömer Göktekin
OBJECTIVE: Treatment of chronic total occlusion (CTO) with everolimus-eluting bioresorbable vascular scaffold (BVS) is safe and effective at short-term follow-up (FU). The current study investigated clinical and angiographic outcomes after treatment of CTO with BVS at >1 year. METHODS: Thirty patients who underwent successful recanalization of 35 CTOs were included in this study. Quantitative coronary angiography (QCA) was performed at median FU period of 402 days...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28044987/drug-eluting-stents-versus-bare-metal-stents-for-the-prevention-of-restenosis-in-patients-with-renovascular-disease
#19
Christian Bradaric, Kristin Eser, Stephanie Preuss, Michael Dommasch, Isabell Wustrow, Nicolas Langwieser, Bernhard Haller, Ilka Ott, Massimiliano Fusaro, Uwe Heemann, Karl-Ludwig Laugwitz, Adnan Kastrati, Tareq Ibrahim
AIMS: To assess the impact of drug-eluting stents (DES) compared to bare-metal stents (BMS) for the endovascular treatment of atherosclerotic renal artery stenosis (ARAS). METHODS AND RESULTS: We retrospectively evaluated all of our endovascular BMS- and DES-implantations performed in de- novo ARAS between 2000-2014 at our institution. The occurrence of in-stent restenosis (ISR) detected by ultrasound or angiography, kidney function, blood pressure (BP), and the number of antihypertensive drugs were analyzed as endpoints...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28043665/angioscopic-observation-of-extremely-late-arterial-repair-after-intracoronary-implantation-of-the-first-generation-sirolimus-eluting-stents
#20
Minoru Ichikawa, Kazunori Bando, Yoshiyuki Kijima
BACKGROUND: Arterial repair delays after intracoronary implantation of Cypher sirolimus-eluting stents (SES), a representative first-generation drug-eluting stent. It remains unclear whether this delay would catch up with bare metal stents (BMS) during extremely long observation. The aim of this study was angioscopic observation of extremely late arterial repair after Cypher SES implantation. METHODS: Thirty-seven SES and 17 BMS were implanted into 22 and 9 patients with angina pectoris, respectively...
December 21, 2016: International Journal of Cardiology
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