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https://www.readbyqxmd.com/read/29332099/association-between-the-intron-8-vntr-polymorphism-of-the-dat1-gene-and-crack-cocaine-addiction
#1
Anderson R Stolf, Diana Müller, Jaqueline B Schuch, Gláucia C Akutagava-Martins, Luciano S P Guimaraes, Claudia M Szobot, Ricardo Halpern, Felix H P Kessler, Flavio Pechansky, Tatiana Roman
BACKGROUND: This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users and nonaddicted individuals. Due to its involvement in drug addiction, this gene is a good candidate for molecular studies. METHODS: A cross-sectional sample of 239 current adult crack abusers or dependents from in- and outpatient clinics and 211 control individuals was collected in Brazil...
January 12, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29321705/attention-deficit-hyperactivity-disorder-and-nicotine-dependence-in-adults
#2
Bülent Bilgi, Umut Mert Aksoy, Özge Şahmelikoğlu Onur, Ayşe Fulya Maner
Introduction: The aim of this study is to assess clinical characteristics and smoking profiles of individuals diagnosed with attention-deficit/hyperactivity disorder (ADHD) and compare their nicotine dependence status with healthy controls for better understanding the mutual and complex relationship between ADHD and smoking. Methods: We included the following participants in the study: 40 adults with the diagnosis of ADHD, 40 participants who visited the smoking cessation polyclinic without any psychiatric disorders, and 40 healthy controls...
December 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29320768/attention-deficit-hyperactivity-disorder-symptoms-are-common-in-patients-in-opioid-maintenance-treatment
#3
Kristine Fiksdal Abel, Edle Ravndal, Thomas Clausen, Jørgen G Bramness
INTRODUCTION AND AIMS: Knowledge of attention deficit hyperactivity disorder (ADHD) symptoms among patients in opioid maintenance treatment (OMT) is important for treatment optimization and yet limited. We investigated the prevalence of ADHD symptoms, and factors associated with high ADHD symptom burden in a group of Norwegian OMT patients. METHODS: We interviewed individuals entering OMT across Norway in 2 steps between 2012 and 2016. ADHD symptoms were measured by the Adult ADHD Self-Report Scale (ASRS; n = 175)...
January 10, 2018: European Addiction Research
https://www.readbyqxmd.com/read/29317844/a-survey-of-adult-referrals-to-specialist-attention-deficit-hyperactivity-disorder-clinics-in-canada
#4
Larry J Klassen, C Matthew Blackwood, Christopher J Reaume, Samuel Schaffer, James G Burns
Background: Canadian guidelines encourage family physicians to diagnose/manage adults with uncomplicated attention-deficit/hyperactivity disorder (ADHD); specialist referral is recommended only for complex cases. This retrospective case review investigated adults referred to Canadian ADHD clinics. Methods: Adult ADHD specialists reviewed referral letters/charts of patients (aged ≥18 years and no family history/known/expressed childhood ADHD) from family physicians/psychiatrists over 2 years...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29317442/maternal-adhd-symptoms-child-adhd-symptoms-and-broader-child-outcomes
#5
Daryl Efron, Kirsten Furley, Alisha Gulenc, Emma Sciberras
OBJECTIVE: This study investigated the associations between maternal symptoms of attention deficit hyperactivity disorder (ADHD) and child functional outcomes in a community-based sample of children with and without ADHD. DESIGN AND SETTING: In this cohort study, children with ADHD and healthy controls were recruited through schools in Melbourne, Australia, using a combined screening (Conners 3 ADHD Index) and case confirmation (Diagnostic Interview Schedule for Children Version IV) procedure...
January 9, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29315559/substance-use-through-adolescence-into-early-adulthood-after-childhood-diagnosed-adhd-findings-from-the-mta-longitudinal-study
#6
Brooke S G Molina, Andrea L Howard, James M Swanson, Annamarie Stehli, John T Mitchell, Traci M Kennedy, Jeffery N Epstein, L Eugene Arnold, Lily Hechtman, Benedetto Vitiello, Betsy Hoza
BACKGROUND: Inconsistent findings exist regarding long-term substance use (SU) risk for children diagnosed with attention-deficit/hyperactivity disorder (ADHD). The observational follow-up of the Multimodal Treatment Study of Children with ADHD (MTA) provides an opportunity to assess long-term outcomes in a large, diverse sample. METHODS: Five hundred forty-seven children, mean age 8.5, diagnosed with DSM-IV combined-type ADHD and 258 classmates without ADHD (local normative comparison group; LNCG) completed the Substance Use Questionnaire up to eight times from mean age 10 to mean age 25...
January 8, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29308693/prevalence-estimates-of-adhd-in-a-sample-of-inpatients-with-alcohol-dependence
#7
Mathias Luderer, Christian Sick, Nurcihan Kaplan-Wickel, Iris Reinhard, Agnes Richter, Falk Kiefer, Tillmann Weber
OBJECTIVE: ADHD is common in patients with alcohol dependence, but prevalence results are inconsistent. We investigated ADHD prevalence in a complex design to avoid over- or underdiagnosing. METHOD: Patients with alcohol dependence starting long-term residential treatment were included. A structured interview (Diagnostic Interview for ADHD in Adults [DIVA]) was conducted on all patients. DIVA results indicating childhood or adulthood ADHD were assessed in successive diagnostic interviews by two expert clinicians...
January 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29305714/diagnoses-of-cardiovascular-disease-or-substance-addiction-abuse-in-us-adults-treated-for-adhd-with-stimulants-or-atomoxetine-is-use-consistent-with-product-labeling
#8
Kathleen A Fairman, Lindsay E Davis, Alyssa M Peckham, David A Sclar
BACKGROUND: Among US adults, utilization of pharmacotherapy for attention-deficit hyperactivity disorder (ADHD) has increased more than ninefold since 1995-1996. Potential contraindications to ADHD pharmacotherapy include serious cardiovascular disease (CVD) and, for stimulants, addictions and bipolar disorder (BPD). OBJECTIVE: To assess the prevalence of potential contraindications among adults treated with ADHD pharmacotherapy. METHODS: A retrospective cohort analysis was performed using the Truven Health MarketScan® database...
January 5, 2018: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29301669/sexually-transmitted-infection-among-adolescents-and-young-adults-with-attention-deficit-hyperactivity-disorder-a-nationwide-longitudinal-study
#9
Mu-Hong Chen, Ju-Wei Hsu, Kai-Lin Huang, Ya-Mei Bai, Nai-Ying Ko, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Shih-Jen Tsai, Tai-Long Pan, Wen-Han Chang, Tzeng-Ji Chen
OBJECTIVE: Previous studies have suggested that attention-deficit/hyperactivity disorder (ADHD) is related to risky sexual behaviors, which have been regarded as a major risk factor of sexually transmitted infection (STI). However, the association between ADHD and subsequent STIs remains unknown. METHOD: Using the Taiwan National Health Insurance Research Database, 17,898 adolescents and young adults who were diagnosed with ADHD by psychiatrists and 71,592 age- and sex-matched comparisons without ADHD were enrolled from 2001 through 2009 and followed to the end of 2011...
January 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29300140/role-of-fault-attributions-and-other-factors-in-adults-attitudes-toward-hypothetical-children-with-an-undesirable-characteristic
#10
Taylor W Wadian, Tammy L Sonnentag, Tucker L Jones, Mark A Barnett
A total of 184 adults read descriptions of six hypothetical children with various undesirable characteristics (i.e., being extremely overweight, extremely aggressive, extremely shy, a poor student, a poor athlete, displaying symptoms of attention deficit hyperactivity disorder). Following each description, the participants were asked to rate how much they disagree or agree that the child, the child's parents, and the child's biological condition (i.e., "something wrong inside the child's body or brain") are at fault for the onset and the perpetuation of the undesirable characteristic...
January 1, 2018: Psychological Reports
https://www.readbyqxmd.com/read/29299870/adhd-in-acute-care-psychiatric-inpatients
#11
Katherine L Lines, Joseph Sadek
Attention-deficit hyperactivity disorder (ADHD) is a neurocognitive disorder characterized by symptoms of inattention, impulsivity and motor hyperactivity. The worldwide prevalence of ADHD, in the general adult population, has been estimated to be 2.8%. Patients with ADHD have a high incidence of comorbidity with other psychiatric disorders. Those with a psychiatric disorder as well as ADHD have more psychosocial difficulties than those without ADHD. Despite knowing that ADHD is often comorbid with other psychiatric diagnoses, there are currently no studies elucidating the prevalence of ADHD in the inpatient psychiatric population, nor is there significant information about its impact...
January 3, 2018: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/29298278/the-impact-of-air-pollution-to-central-nervous-system-in-children-and-adults
#12
Radim J Sram, Milos Veleminsky, Milos Veleminsky, Jana Stejskalová
The aim of this paper was to review studies analyzing the associations between air pollution and neurodevelopment in children as well as the effect on adult population. Effect of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs, benzo[a]pyrene, B[a]P) were already studied on cohorts from New York, Poland, China, and Spain. All results indicate changes of child behavior and neurodevelopment at the age of 3-9 years, decrease of IQ, increase of Attention Deficit Hyperactivity Disorder (ADHD), decrease of brain-derived neurotrophic factor (BDNF), reduction of left hemisphere white matter...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29295472/a-prospective-birth-cohort-study-on-maternal-cholesterol-levels-and-offspring-attention-deficit-hyperactivity-disorder-new-insight-on-sex-differences
#13
Yuelong Ji, Anne W Riley, Li-Ching Lee, Heather Volk, Xiumei Hong, Guoying Wang, Rayris Angomas, Tom Stivers, Anastacia Wahl, Hongkai Ji, Tami R Bartell, Irina Burd, David Paige, Margaret D Fallin, Barry Zuckerman, Xiaobin Wang
Growing evidence suggests that maternal cholesterol levels are important in the offspring's brain growth and development. Previous studies on cholesterols and brain functions were mostly in adults. We sought to examine the prospective association between maternal cholesterol levels and the risk of attention deficit hyperactivity disorder (ADHD) in the offspring. We analyzed data from the Boston Birth Cohort, enrolled at birth and followed from birth up to age 15 years. The final analyses included 1479 mother-infant pairs: 303 children with ADHD, and 1176 neurotypical children without clinician-diagnosed neurodevelopmental disorders...
December 23, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29291476/neurodevelopmental-disorders-in-prison-inmates-comorbidity-and-combined-associations-with-psychiatric-symptoms-and-behavioural-disturbance
#14
Susan Young, Rafael A González, Hannah Mullens, Laura Mutch, Isabella Malet-Lambert, Gisli H Gudjonsson
The identification and management of inmates with neurodevelopmental disorders (ND) has been insufficiently addressed in the literature. We estimated the proportion of cases with Attention deficit/hyperactivity disorder (ADHD), Autism spectrum disorder (ASD) and Intellectual disability (ID) in prison, their comorbidity, and associations with disruptive behaviours and with psychiatric symptoms. Further, we examined the role of coexisting ND on psychiatric symptoms and attitudes toward violence. All 390 male inmates underwent an assessment that included the Diagnostic Interview for ADHD in Adults 2...
December 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29291475/brain-arousal-regulation-in-adults-with-attention-deficit-hyperactivity-disorder-adhd
#15
Maria Strauß, Christine Ulke, Madlen Paucke, Jue Huang, Nicole Mauche, Christian Sander, Tetyana Stark, Ulrich Hegerl
The main aim of the current study was to test the hypothesis that adult patients with attention-deficit/hyperactivity disorder (ADHD) have less stable brain arousal regulation than healthy controls. We objectively assessed brain arousal regulation using the Vigilance Algorithm Leipzig (VIGALL 2.1) to analyze 15-min resting EEG data of thirty-three ADHD patients and thirty-five matched controls. Based on automatically classified 1-s segments we computed mean EEG-vigilance (indexing arousal level) and arousal stability score (indexing arousal regulation)...
December 18, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29282731/cognitive-behavioural-therapy-for-adult-attention-deficit-hyperactivity-disorder-a-proof-of-concept-randomised-controlled-trial
#16
A J Dittner, J Hodsoll, K A Rimes, A J Russell, T Chalder
OBJECTIVE: To investigate efficacy, patient acceptability and feasibility of formulation-based cognitive-behavioural therapy (CBT) for adults with attention-deficit hyperactivity disorder (ADHD). NICE guidelines for adult ADHD recommend further research into psychological treatments. METHOD: Sixty participants with adult ADHD were randomly allocated to treatment as usual (TAU) vs. TAU plus up to 16 sessions of individual formulation-based CBT for ADHD. RESULTS: Adding formulation-based CBT to TAU for ADHD significantly improved ADHD symptoms on the Barkley Current Symptoms Scale and scores on the Work and Social Adjustment Scale...
December 27, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29280392/comorbidity-of-internet-use-disorder-and-attention-deficit-hyperactivity-disorder-two-adult-case-control-studies
#17
Martin Bielefeld, Marion Drews, Inken Putzig, Laura Bottel, Toni Steinbüchel, Jan Dieris-Hirche, Gregor R Szycik, Astrid Müller, Mandy Roy, Martin Ohlmeier, Bert Theodor Te Wildt
Objectives There is good scientific evidence that attention deficit hyperactivity disorder (ADHD) is both a predictor and a comorbidity of addictive disorders in adulthood. These associations not only focus on substance-related addictions but also on behavioral addictions like gambling disorder and Internet use disorder (IUD). For IUD, systematic reviews have identified ADHD as one of the most prevalent comorbidities besides depressive and anxiety disorders. Yet, there is a need to further understand the connections between both disorders to derive implications for specific treatment and prevention...
December 1, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29274569/risk-factors-for-adverse-driving-outcomes-in-dutch-adults-with-adhd-and-controls
#18
Tannetje I Bron, Denise Bijlenga, Minda Breuk, Marieke Michielsen, Aartjan T F Beekman, J J Sandra Kooij
OBJECTIVE: To identify risk factors for adverse driving outcomes and unsafe driving among adults with and without ADHD in a Dutch sample. METHODS: In this cross-sectional study, validated self-report questionnaires were used to compare driving history and current driving behavior between 330 adults diagnosed with ADHD and 330 controls. RESULTS: Adults with ADHD had significantly more adverse driving outcomes when compared to controls. Having an ADHD diagnosis significantly increased the odds for having had 3 or more vehicular crashes (OR = 2...
December 20, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29259561/aberrant-spatial-and-temporal-prefrontal-activation-patterns-in-medication-na%C3%A3-ve-adults-with-adhd
#19
Bun Yamagata, Yuichi Takei, Takashi Itahashi, Shenghong Pu, Jinichi Hirano, Masaru Mimura, Akira Iwanami
Previous near-infrared spectroscopy (NIRS) studies using a verbal fluency task (VFT) have consistently reported that adults with attention-deficit hyperactivity disorder (ADHD) showed significantly smaller oxygenated-hemoglobin [oxy-Hb] activations in the prefrontal cortex (PFC) compared to those in healthy controls (HC). Despite this consistent evidence of brain dysfunction in ADHD, ADHD is currently diagnosed based only on subjective clinical and scoring measures, which are often unreliable. Hence, it is necessary to establish objective neuroimaging biomarkers for ADHD...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29240924/effect-of-omega-3-fatty-acids-on-cognition-an-updated-systematic-review-of-randomized-clinical-trials
#20
Oscar D Rangel-Huerta, Angel Gil
Context: The increasing number of studies on the effects of n-3 long-chain polyunsaturated fatty acids (LC-PUFAs) on health, particularly cognition, in the last 5 years reflects the growing interest in this area of research. Objective: The aim for this systematic review was to evaluate the scientific evidence published in the last 5 years (2012-2017) on the effects of n-3 LC-PUFA intake on cognition, cognitive development, and cognitive decline to determine whether n-3 LC-PUFAs support cognitive development and prevent cognitive decline...
December 12, 2017: Nutrition Reviews
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