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https://www.readbyqxmd.com/read/29453069/combined-effect-of-copper-and-hydrodynamic-conditions-on-myriophyllum-alterniflorum-biomarkers
#1
Maha Krayem, Véronique Deluchat, Philippe Hourdin, Patrice Fondanèche, Florence Lecavelier Des Etangs, Véronique Kazpard, Christian Moesch, Pascal Labrousse
The aim of this study is to determine the combined effect of copper and hydrodynamic conditions on the response of certain biomarkers of an aquatic macrophyte, namely Myriophyllum alterniflorum. Watermilfoil biomarkers are monitored in a synthetic medium enriched or not with copper (100 μg.L -1 ) for 21 days in aquarium systems (150 L), under three hydrodynamic conditions: laminar, turbulent, and calm. The studied biomarkers are: respiratory and photosynthetic activities; concentrations of chlorophyll a, b and carotenoids; osmotic potential; hydrogen peroxide content; and growth...
February 9, 2018: Chemosphere
https://www.readbyqxmd.com/read/29452534/co-culture-of-human-bone-marrow-mesenchymal-stem-cells-and-macrophages-attenuates-lipopolysaccharide-induced-inflammation-in-human-corneal-epithelial-cells
#2
Won-Yong Jeong, Ji-Hye Kim, Chan-Wha Kim
Dry eye syndrome (DES) is considered as an ocular surface inflammatory disease. Previous studies have shown inflammation plays an important role in the progression and onset of DES. Co-culture of human bone marrow mesenchymal stem cells (HBMSCs) and macrophages showed immunomodulatory effects via regulation of cytokine regulation. Thus, the aim of this study was to investigate the effect of the interaction of these cells on in vitro DES model. The conditioned media (CM) from macrophages, HBMSCs, and HBMSCs + macrophages were treated to human corneal epithelial cells, which showed significant reduction in IL-1α and IL-1β expression levels in HBMSCs + macrophages group...
February 16, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29450948/aduc-prizes-carl-duisberg-memorial-award-for-bill-morandi-new-members-of-the-acad%C3%A3-mie-des-sciences-max-delbr%C3%A3-ck-junior-prize-for-sabrina-disch-novartis-early-career-award
#3
(no author information available yet)
No abstract text is available yet for this article.
February 16, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29450897/molecular-imprinted-polymers-based-on-magnetic-chitosan-with-different-deep-eutectic-solvent-monomers-for-the-selective-separation-of-catechins-in-black-tea
#4
Wanwan Ma, Yunliang Dai, Kyung Ho Row
Two types of molecular-imprinted polymers-based magnetic chitosan with facile deep eutectic solvent-functional monomers (Fe 3 O 4 -CTS@DES-MIPs) were synthesized and applied as adsorbents in magnetic solid-phase extraction (MSPE) for the selective recognition and separation of (+)-catechin, (-)-epicatechin, and (-)-epigallocatechin gallate in black tea. The obtained Fe 3 O 4 -CTS@DES-MIPs were characterized by Fourier transform infrared spectroscopy and field emission scanning electron microscopy. The selective recognition ability was examined by adsorption experiments...
February 16, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29450452/effect-of-neoadjuvant-chemotherapy-plus-regional-hyperthermia-on-long-term-outcomes-among-patients-with-localized-high-risk-soft-tissue-sarcoma-the-eortc-62961-esho-95-randomized-clinical-trial
#5
Rolf D Issels, Lars H Lindner, Jaap Verweij, Rüdiger Wessalowski, Peter Reichardt, Peter Wust, Pirus Ghadjar, Peter Hohenberger, Martin Angele, Christoph Salat, Zeljko Vujaskovic, Soeren Daugaard, Olav Mella, Ulrich Mansmann, Hans Roland Dürr, Thomas Knösel, Sultan Abdel-Rahman, Michael Schmidt, Wolfgang Hiddemann, Karl-Walter Jauch, Claus Belka, Alessandro Gronchi
Importance: Patients with soft tissue sarcoma are at risk for local recurrence and distant metastases despite optimal local treatment. Preoperative anthracycline plus ifosfamide chemotherapy improves outcome in common histological subtypes. Objective: To analyze whether the previously reported improvement in local progression-free survival by adding regional hyperthermia to neoadjuvant chemotherapy translates into improved survival. Design, Setting, and Participants: Open-label, phase 3 randomized clinical trial to evaluate the efficacy and toxic effects of neoadjuvant chemotherapy plus regional hyperthermia...
February 15, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29449885/deep-eutectic-solvents-pretreatment-of-agro-industrial-food-waste
#6
Alessandra Procentese, Francesca Raganati, Giuseppe Olivieri, Maria Elena Russo, Lars Rehmann, Antonio Marzocchella
Background: Waste biomass from agro-food industries are a reliable and readily exploitable resource. From the circular economy point of view, direct residues from these industries exploited for production of fuel/chemicals is a winning issue, because it reduces the environmental/cost impact and improves the eco-sustainability of productions. Results: The present paper reports recent results of deep eutectic solvent (DES) pretreatment on a selected group of the agro-industrial food wastes (AFWs) produced in Europe...
2018: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29448619/improved-dissolution-and-oral-bioavailability-of-celecoxib-by-a-dry-elixir-system
#7
Kwan Hyung Cho, Jun-Pil Jee, Da A Yang, Sung Tae Kim, Dongjin Kang, Dae-Young Kim, Taeyong Sim, Sang Yeob Park, Kyeongsoon Kim, Dong-Jin Jang
The purpose of this study was to develop and evaluate a dry elixir (DE) system for enhancing the dissolution rate and oral bioavailability of celecoxib. DE system has been used for improving solubility, oral bioavailability of poorly water-soluble drugs. The encapsulated drugs or solubilized drugs in the matrix are rapidly dissolved due to the co-solvent effect, resting in both an enhanced dissolution and bioavailability. DEs containing celecoxib were prepared by spray-drying method and characterized by morphology, drug/ethanol content, drug crystallinity, dissolution rate and oral bioavailability...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29447787/rationale-and-design-of-the-comparison-between-a-p2y12-inhibitor-monotherapy-versus-dual-antiplatelet-therapy-in-patients-undergoing-implantation-of-coronary-drug-eluting-stents-smart-choice-a-prospective-multicenter-randomized-trial
#8
Young Bin Song, Seok Kyu Oh, Ju-Hyeon Oh, Eul-Soon Im, Deok-Kyu Cho, Byung Ryul Cho, Jong-Young Lee, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Jin-Ho Choi, Seung-Hyuck Choi, Sang Hoon Lee, Hyeon-Cheol Gwon, Joo-Yong Hahn
BACKGROUND AND RATIONALE: Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor reduces thrombotic events in patients undergoing percutaneous coronary intervention (PCI), but these benefits come at the expense of increased risk of bleeding when compared with aspirin monotherapy. It is unclear whether P2Y12 inhibitor monotherapy might maintain anti-ischemic efficacy while reducing the bleeding risk compared with DAPT after implantation of the current generation of drug-eluting stents (DES)...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447782/comparison-of-drug-eluting-stents-and-drug-coated-balloon-for-the-treatment-of-drug-eluting-coronary-stent-restenosis-a-randomized-restore-trial
#9
Yiu Tung Anthony Wong, Do-Yoon Kang, Jin Bae Lee, Seung-Woon Rha, Young Joon Hong, Eun-Seok Shin, Sung-Ho Her, Chang Wook Nam, Woo-Young Chung, Moo Hyun Kim, Cheol Hyun Lee, Pil Hyung Lee, Jung-Min Ahn, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park, Duk-Woo Park, Seung-Jung Park
BACKGROUND: This study sought to evaluate the optimal treatment for in-stent restenosis (ISR) of drug-eluting stents (DESs). METHODS: This is a prospective, multicenter, open-label, randomized study comparing the use of drug-eluting balloon (DEB) versus second-generation everolimus-eluting stent for the treatment of DES ISR. The primary end point was in-segment late loss at 9-month routine angiographic follow-up. RESULTS: A total of 172 patients were enrolled, and 74 (43...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447774/percutaneous-coronary-intervention-of-lesions-with-in-stent-restenosis-a-report-from-the-adapt-des-study
#10
Björn Redfors, Philippe Généreux, Bernhard Witzenbichler, Akiko Maehara, Giora Weisz, Thomas McAndrew, Roxana Mehran, Ajay J Kirtane, Gregg W Stone
BACKGROUND: There is a paucity of data from large contemporary cohorts of patients with in-stent restenosis (ISR) treated with drug-eluting stents (DESs), and no studies have examined the impact of high platelet reactivity (HPR) on the occurrence of ischemic events after ISR percutaneous coronary intervention (PCI) with DESs. We sought to report outcomes after PCI of ISR lesions and its association with HPR. METHODS: Patients in the prospective, multicenter ADAPT-DES study were stratified according to whether they had ISR versus non-ISR PCI...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447770/efficacy-and-safety-of-dual-antiplatelet-therapy-after-coronary-stenting-in-patients-with-chronic-kidney-disease
#11
Doyeon Hwang, Kyung Woo Park, Joo Myung Lee, Tae-Min Rhee, Myeong-Ki Hong, Yangsoo Jang, Marco Valgimigli, Antonio Colombo, Martine Gilard, Tullio Palmerini, Gregg W Stone, Hyo-Soo Kim
BACKGROUND: We compared efficacy and safety of short- (3 or 6 months) versus long-term (≥12 months) dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation, according to the presence of chronic kidney disease (CKD). METHODS: Patient-level pooled analysis was performed with 7242 patients (87.2% with 2nd generation DES) from 5 randomized controlled trials. RESULTS: In both CKD (1273 patients) and non-CKD (5969 patients) population, the rates of patient-oriented composite outcomes at 1-year (POCO, all-cause death, any myocardial infarction [MI], stroke and TIMI major bleeding) were not different between the short- and long-term DAPT (hazard ratio [HR] 1...
March 2018: American Heart Journal
https://www.readbyqxmd.com/read/29447727/n-o-129-l-exercice-physique-pendant-la-grossesse-et-le-postpartum
#12
Gregory A L Davies, Larry A Wolfe, Michelle F Mottola, Catherine MacKinnon
OBJECTIF: Énoncer une directive canadienne visant à informer les fournisseurs de soins obstétricaux des répercussions, pour la mère, le fœtus et le nouveau-né, des exercices de conditionnement aerobique et musculaire pendant la grossesse. RéSULTATS ATTENDUS: Effets sur la morbidité maternelle, fœtale et néonatale et mesures de la forme physique maternelle. PREUVES: Une recherche sur MEDLINE des articles, publiés en anglais de 1966 à 2002, appartenant aux catégories suivantes : études sur le conditionnement aérobique et musculaire chez des femmes ne faisant pas jusque-là d'exercice et chez des femmes actives avant leur grossesse, ainsi que des études sur les répercussions du conditionnement aérobique et musculaire sur les issues précoces et tardives de la grossesse ou sur les issues néonatales; rapports de synthèse et méta-analyses portant sur l'exercice pendant la grossesse...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447715/n-o-163-prise-en-charge-gyn%C3%A3-cologique-et-obst%C3%A3-tricale-des-femmes-pr%C3%A3-sentant-une-coagulopathie-h%C3%A3-r%C3%A3-ditaire
#13
Christine Demers, Christine Derzko, Michele David, Joanne Douglas
No abstract text is available yet for this article.
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447700/un-cas-de-d%C3%A3-c%C3%A3-s-d%C3%A3-coulant-des-complications-d-une-grossesse-dans-une-corne-ut%C3%A3-rine-rudimentaire
#14
Hana Harzallah, Mehdi Ben Khelil, Moncef Hamdoun
No abstract text is available yet for this article.
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29447674/green-modified-micellar-liquid-chromatography-for-isocratic-isolation-of-some-cardiovascular-drugs-with-different-polarities-through-experimental-design-approach
#15
Amir M Ramezani, Ghodratollah Absalan, Raheleh Ahmadi
Bilayer pseudo-stationary phase micellar liquid chromatography (MLC) was developed for simultaneous isocratic isolation of hydrochlorothiazide, as a basic-polar (hydrophilic) cardiovascular drug, as well as triamterene and losartan potassium, as acidic-nonpolar (hydrophobic) cardiovascular drugs. Utilizing a deep eutectic solvent (DES), as a novel green mobile phase additive in combination with acetonitrile (ACN) and acetic acid (ACA), drastically improved the chromatographic behavior of the drugs. Concentration of sodium dodecyl sulphate (SDS), as well as volume percentages of ACN, DES, and ACA were optimized by using a central composite design...
June 20, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29443486/effects-on-patients-of-variations-in-the-implementation-of-a-cardiometabolic-risk-intervention-program-in-montr%C3%A3-al
#16
Marie-Ève Beauregard, Sylvie Provost, Raynald Pineault, Dominique Grimard, José Pérez, Michel Fournier
INTRODUCTION: In 2011, the Agence de la santé et des services sociaux de Montréal (ASSSM), in partnership with the region's Centres de santé et de services sociaux (CSSS), coordinated the implementation of a program on cardiometabolic risk based on the Chronic Care Model. The program, intended for patients suffering from diabetes or hypertension, involved a series of individual follow-up appointments, group classes and exercise sessions. Our study assesses the impact on patient health outcomes of variations in the implementation of some aspects of the program among the six CSSSs taking part in the study...
February 2018: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29441749/clinical-significance-of-newly-diagnosed-diabetes-mellitus-in-the-era-of-des-for-acute-myocardial-infarction
#17
EDITORIAL
Hun Jun Park
No abstract text is available yet for this article.
February 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29441493/model-based-economic-evaluation-of-treatments-for-depression-a-systematic-literature-review
#18
REVIEW
Spyros Kolovos, Judith E Bosmans, Heleen Riper, Karine Chevreul, Veerle M H Coupé, Maurits W van Tulder
BACKGROUND: An increasing number of model-based studies that evaluate the cost effectiveness of treatments for depression are being published. These studies have different characteristics and use different simulation methods. OBJECTIVE: We aimed to systematically review model-based studies evaluating the cost effectiveness of treatments for depression and examine which modelling technique is most appropriate for simulating the natural course of depression. METHODS: The literature search was conducted in the databases PubMed, EMBASE and PsycInfo between 1 January 2002 and 1 October 2016...
September 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29439589/measurement-properties-of-the-dutch-unit%C3%A3-rhumatologique-des-affections-de-la-main-and-its-ability-to-measure-change-due-to-dupuytren-s-disease-progression-compared-with-the-michigan-hand-outcomes-questionnaire
#19
Dieuwke C Broekstra, Edwin R van den Heuvel, Rosanne Lanting, Paul M N Werker
Data of a prospective longitudinal cohort study including 233 Dupuytren's patients was used to determine: (1) whether the Unité Rhumatologique des Affections de la Main scale and Michigan Hand outcomes Questionnaire can detect change in hand function due to Dupuytren's disease progression and to compare their abilities; (2) the concurrent validity, reliability, responsiveness and interpretability of the Dutch Unité Rhumatologique des Affections de la Main. The Unité Rhumatologique des Affections de la Main and Michigan Hand outcomes Questionnaire had comparable measurement properties, and were both able to distinguish participants with disease progression from those without progression (resp...
January 1, 2018: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29439299/recurrent-in-stent-restenosis-in-the-area-of-previous-stent-fracture-a-management-dilemma
#20
Udit Bhaskar Bhatnagar, Josh Rezkalla, Tomasz Stys, Adam Stys
Drug eluting stents (DES) have been increasingly being used for treatment of coronary artery disease (CAD) and have been shown to be very effective in prevention of primary in-stent restenosis (ISR). However DES have been increasingly associated with acute to subacute risk of stent fractures (SF). There is also a paucity of data about different management strategies for SF, especially in the long term. We present a case of recurrent ISR in an area of previous acute SF at the touchdown of saphenous venous graft (SVG) to first diagonal artery (D1)...
January 2018: South Dakota Medicine: the Journal of the South Dakota State Medical Association
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