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https://www.readbyqxmd.com/read/28173886/comparison-of-the-dsm-5-and-icd-10-panic-and-other-anxiety-disorders
#1
Borwin Bandelow
Anxiety disorders are the most prevalent mental disorders and are associated with substantial healthcare costs and a high burden of disease. In this article, changes in the new Diagnostic and Statistical Manual for Mental Disorders (the DSM-5) with respect to panic disorder/agoraphobia, generalized anxiety disorder, social anxiety disorder, specific phobias, and selective mutism are compared with the International Classification of Diseases (ICD-10) system.
February 8, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28167838/glrb-allelic-variation-associated-with-agoraphobic-cognitions-increased-startle-response-and-fear-network-activation-a-potential-neurogenetic-pathway-to-panic-disorder
#2
J Deckert, H Weber, C Villmann, T B Lonsdorf, J Richter, M Andreatta, A Arias-Vasquez, L Hommers, L Kent, C Schartner, S Cichon, C Wolf, N Schaefer, C R von Collenberg, B Wachter, R Blum, D Schümann, R Scharfenort, J Schumacher, A J Forstner, C Baumann, M A Schiele, S Notzon, P Zwanzger, J G E Janzing, T Galesloot, L A Kiemeney, A Gajewska, E Glotzbach-Schoon, A Mühlberger, G Alpers, T Fydrich, L Fehm, A L Gerlach, T Kircher, T Lang, A Ströhle, V Arolt, H-U Wittchen, R Kalisch, C Büchel, A Hamm, M M Nöthen, M Romanos, K Domschke, P Pauli, A Reif
The molecular genetics of panic disorder (PD) with and without agoraphobia (AG) are still largely unknown and progress is hampered by small sample sizes. We therefore performed a genome-wide association study with a dimensional, PD/AG-related anxiety phenotype based on the Agoraphobia Cognition Questionnaire (ACQ) in a sample of 1370 healthy German volunteers of the CRC TRR58 MEGA study wave 1. A genome-wide significant association was found between ACQ and single non-coding nucleotide variants of the GLRB gene (rs78726293, P=3...
February 7, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28160720/increasing-valued-behaviors-precedes-reduction-in-suffering-findings-from-a-randomized-controlled-trial-using-act
#3
Andrew T Gloster, Jens Klotsche, Joseph Ciarrochi, Georg Eifert, Rainer Sonntag, Hans-Ulrich Wittchen, Jürgen Hoyer
BACKGROUND: Psychological flexibility theory (PFT) suggests three key processes of change: increases in value-directed behaviors, reduction in struggle with symptoms, and reduction in suffering. We hypothesized that Acceptance and Commitment Therapy (ACT) would change these processes and that increases in valued action and decreases in struggle would precede change in suffering. METHOD: Data were derived from a randomized clinical trial testing ACT (vs. waitlist) for treatment-resistant patients with primary panic disorder with/without agoraphobia (n = 41)...
January 24, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28152236/gender-differences-among-treatment-seeking-adults-with-cannabis-use-disorder-clinical-profiles-of-women-and-men-enrolled-in-the-achieving-cannabis-cessation-evaluating-n-acetylcysteine-treatment-accent-study
#4
Brian J Sherman, Aimee L McRae-Clark, Nathaniel L Baker, Susan C Sonne, Therese K Killeen, Kasie Cloud, Kevin M Gray
BACKGROUND AND OBJECTIVES: Recent evidence suggests that women may fare worse than men in cannabis trials with pharmacologic interventions. Identifying baseline clinical profiles of treatment-seeking cannabis-dependent adults could inform gender-specific treatment planning and development. METHODS: The current study compared baseline demographic, cannabis use, and psychiatric factors between women (n = 86) and men (n = 216) entering the Achieving Cannabis Cessation-Evaluating N-acetylcysteine Treatment (ACCENT) study, a multi-site, randomized controlled trial conducted within the National Drug Abuse Treatment Clinical Trials Network...
February 2, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28144878/diverse-profiles-of-anxiety-related-disorders-in-fragile-x-cornelia-de-lange-and-rubinstein-taybi-syndromes
#5
Hayley Crawford, Jane Waite, Chris Oliver
Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein-Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive-compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive-compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive-compulsive subscales...
January 31, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28122091/d-cycloserine-augmentation-of-exposure-based-cognitive-behavior-therapy-for-anxiety-obsessive-compulsive-and-posttraumatic-stress-disorders-a-systematic-review-and-meta-analysis
#6
David Mataix-Cols, Lorena Fernández de la Cruz, Benedetta Monzani, David Rosenfield, Erik Andersson, Ana Pérez-Vigil, Paolo Frumento, Rianne A de Kleine, JoAnn Difede, Boadie W Dunlop, Lara J Farrell, Daniel Geller, Maryrose Gerardi, Adam J Guastella, Stefan G Hofmann, Gert-Jan Hendriks, Matt G Kushner, Francis S Lee, Eric J Lenze, Cheri A Levinson, Harry McConnell, Michael W Otto, Jens Plag, Mark H Pollack, Kerry J Ressler, Thomas L Rodebaugh, Barbara O Rothbaum, Michael S Scheeringa, Anja Siewert-Siegmund, Jasper A J Smits, Eric A Storch, Andreas Ströhle, Candyce D Tart, David F Tolin, Agnes van Minnen, Allison M Waters, Carl F Weems, Sabine Wilhelm, Katarzyna Wyka, Michael Davis, Christian Rück
Importance: Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclear. Objective: To clarify whether DCS is superior to placebo in augmenting the effects of cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to evaluate whether antidepressants interact with DCS and the effect of potential moderating variables...
January 25, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28114915/transdiagnostic-group-cbt-vs-standard-group-cbt-for-depression-social-anxiety-disorder-and-agoraphobia-panic-disorder-study-protocol-for-a-pragmatic-multicenter-non-inferiority-randomized-controlled-trial
#7
Sidse M Arnfred, Ruth Aharoni, Morten Hvenegaard, Stig Poulsen, Bo Bach, Mikkel Arendt, Nicole K Rosenberg, Nina Reinholt
BACKGROUND: Transdiagnostic Cognitive Behavior Therapy (TCBT) manuals delivered in individual format have been reported to be just as effective as traditional diagnosis specific CBT manuals. We have translated and modified the "The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders" (UP-CBT) for group delivery in Mental Health Service (MHS), and shown effects comparable to traditional CBT in a naturalistic study. As the use of one manual instead of several diagnosis-specific manuals could simplify logistics, reduce waiting time, and increase therapist expertise compared to diagnosis specific CBT, we aim to test the relative efficacy of group UP-CBT and diagnosis specific group CBT...
January 23, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28096880/genetic-polymorphism-of-1019c-g-rs6295-promoter-of-serotonin-1a-receptor-and-catechol-o-methyltransferase-in-panic-disorder
#8
Takashi Watanabe, Shin Ishiguro, Akiko Aoki, Mikito Ueda, Yuki Hayashi, Kazufumi Akiyama, Kazuko Kato, Kazutaka Shimoda
OBJECTIVE: Family and twin studies have suggested genetic liability for panic disorder (PD) and therefore we sought to determine the role of noradrenergic and serotonergic candidate genes for susceptibility for PD in a Japanese population. METHODS: In this age- and gender-matched case-control study involving 119 PD patients and 119 healthy controls, we examined the genotype distributions and allele frequencies of the serotonin transporter gene linked polymorphic region (5-HTTLPR), -1019C/G (rs6295) promoter polymorphism of the serotonin receptor 1A (5-HT1A), and catechol-O-methyltransferase (COMT) gene polymorphism (rs4680) and their association with PD...
January 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28045286/perceived-criticism-predicts-outcome-of-psychotherapy-for-panic-disorder-replication-and-extension
#9
Dianne L Chambless, Kelly M Allred, Fang Fang Chen, Kevin S McCarthy, Barbara Milrod, Jacques P Barber
OBJECTIVE: We tested the relation of perceived criticism (PC) from a parent or spouse/romantic partner to outcome of psychotherapy for panic disorder (PD). METHOD: Participants were 130 patients with PD (79% with agoraphobia) who received 24 twice-weekly sessions of panic-focused psychodynamic psychotherapy, cognitive-behavioral therapy, or applied relaxation therapy. Patients were predominantly White (75%), female (64%), and non-Hispanic (85%). At baseline, Week 5 of treatment, termination, and at 6- and 12-month follow-up, patients rated PC from the relative with whom they lived...
January 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28017851/immediate-and-delayed-anxiety-and-depression-like-profiles-in-the-adolescent-wistar-kyoto-rat-model-of-endogenous-depression-following-postweaning-social-isolation
#10
Reshma A Shetty, Monika Sadananda
In order to understand links that exist between inherited risk or predisposition, brain and behavioural development, endocrine regulation and social/environmental stimuli, animal models are crucial. The Wistar-Kyoto (WKY) rat has been shown to have validity as a model of adult and adolescent depression. While sex- and age-specific differences in some of the face, predictive and construct validities of the model such as depression-like behaviours have been established, anhedonia and anxiety using other induced anxiety paradigms such as elevated plus maze remain equivocal...
December 23, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27995827/prevalence-of-current-anxiety-disorders-in-people-with-bipolar-disorder-during-euthymia-a-meta-analysis
#11
B Pavlova, R H Perlis, O Mantere, C M Sellgren, E Isometsä, P B Mitchell, M Alda, R Uher
BACKGROUND: Anxiety disorders are highly prevalent in people with bipolar disorder, but it is not clear how many have anxiety disorders even at times when they are free of major mood episodes. We aimed to establish what proportion of euthymic individuals with bipolar disorder meet diagnostic criteria for anxiety disorders. METHOD: We performed a random-effects meta-analysis of prevalence rates of current DSM-III- and DSM-IV-defined anxiety disorders (panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder, specific phobia, obsessive-compulsive disorder, post-traumatic stress disorder, and anxiety disorder not otherwise specified) in euthymic adults with bipolar disorder in studies published by 31 December 2015...
December 20, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27987430/effects-of-the-cortisol-stress-response-on-the-psychotherapy-outcome-of-panic-disorder-patients
#12
Susann Wichmann, Clemens Kirschbaum, Thomas Lorenz, Katja Petrowski
BACKGROUND: A proportion of patients with panic disorder (PD) fail to show a remission after psychotherapy. Biological correlates of psychotherapy non-response have rarely been described in the literature. The aim of the present study was to research the relationship between the cortisol stress response and the psychotherapy outcome in PD patients. METHODS: Twenty-eight PD patients (20 females, mean age±SD: 35.71±13.18) seeking psychological treatment for PD and n=32 age- and sex-matched healthy control participants (21 females, aged 34...
November 30, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27971383/excess-costs-of-panic-disorder-with-or-without-agoraphobia-in-germany-the-application-of-entropy-balancing-to-multiple-imputed-datasets
#13
C Brettschneider, F Bleibler, T Hiller, A Konnopka, J Breitbart, J Margraf, J Gensichen, H König
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27951417/synthesis-and-evaluation-of-analgesic-behavioral-effects-and-chronic-toxicity-of-the-new-3-5-diaminopyrazole-and-its-precursor-the-thiocyanoacetamide
#14
Ridha Ben Ali, Amal Ben Othman, Khouloud Bokri, Samira Maghraoui, Adel Hajri, Azaiez Ben Akacha, Chadli Dziri, Michèle Véronique El May
This study aimed to explore the analgesic, antioxidant, behavioral and toxicological effects of 3,5-diaminopyrazole and thiocyanoacetamide. Caffeine was used as reference drug whose effects are known after oral treatment with an efficient dose (10mg/kg/day) for 30days. The preliminary bioassays indicated that both compounds at this dose have strong antioxidant capacities and present highly analgesic effects. The behavioral study showed an activation of the rat memory by thiocyanoacetamide. This molecule caused a phobia state to open areas in the elevated plus maze and specifically agoraphobia in the open field with a lack in the development of the exploratory capacity...
February 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27931891/a-systematic-review-of-anxiety-prevalence-in-adults-within-primary-care-and-community-settings-in-malaysia
#15
REVIEW
Chin Hoong Wong, Zia U Bakt Sultan Shah, Cheong Lieng Teng, Tzi Quen Lin, Zainab Abdul Majeed, Chun Wai Chan
BACKGROUND: Anxiety disorders are common mental health disorders with significant impact on the individual as well as burden on the country as a whole. METHODS: A systematic review of databases, reference lists, internet sources, and input from content experts revealed 42 studies that documented the prevalence of anxiety symptoms or disorders. 12 of these studies specifically evaluated anxiety disorders. RESULTS: 4 studies looked at the prevalence of anxiety disorders in the general population, whilst the remainder focused on selected population groups: university students (4 studies); substance abuse (3 studies); and victims of abuse (1 study)...
December 2016: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/27898206/doomed-for-disorder-high-incidence-of-mood-and-anxiety-disorders-in-offspring-of-depressed-and-anxious-patients-a-prospective-cohort-study
#16
Petra J Havinga, Lynn Boschloo, Annelene J P Bloemen, Maaike H Nauta, Sybolt O de Vries, Brenda W J H Penninx, Robert A Schoevers, Catharina A Hartman
OBJECTIVE: Early recognition of individuals at risk for depressive and anxiety disorders is key in influencing onset and course of these disorders. Parental history is a potent risk factor for the development of these disorders in offspring. However, knowledge about the magnitude of this risk is limited as large-scale longitudinal studies with a follow-up into adulthood are scarce. Those offspring at highest risk may possibly be identified by easy-to-determine parental psychiatric characteristics, family context, and offspring characteristics...
January 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27876300/functional-voice-disorders-the-importance-of-the-psychologist-in-clinical-voice-assessment
#17
Mafalda Andrea, Óscar Dias, Mário Andrea, Maria Luísa Figueira
OBJECTIVES: The etiopathogenesis of functional voice disorders (FVDs) is multifactorial. The purpose of this study was to analyze the severity of depression and anxiety, and the incidence of affective and anxiety disorders, in patients who presented different types of FVDs and were followed at the University Clinic of Otolaryngology. DESIGN: This is a cross-sectional study. METHODS: After ENT observation, 83 women were classified into three groups: psychogenic voice disorder (PVD = 39), primary muscle tension voice disorder (MTVD1 = 16), and secondary muscle tension voice disorder (MTVD2 = 28)...
November 18, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27861457/burden-and-distress-in-caregivers-of-patients-with-panic-disorder-and-agoraphobia
#18
Evandro Luis Pampani Borgo, Ana Teresa de Abreu Ramos-Cerqueira, Albina Rodrigues Torres
We estimated the prevalence, severity, and correlates of burden and distress in caregivers of patients with panic disorder and agoraphobia. The instruments used in this cross-sectional study with 40 caregivers and 40 outpatients were Carer Burden Interview (CBI), Family Burden Interview Schedule (FBIS-BR), Self-Reporting Questionnaire (SRQ), Panic and Agoraphobia Scale (PAS), and Mini-international Neuropsychiatric Interview. Bivariate analyses were followed by regression analyses. The patients' mean PAS score was 29...
January 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/27855338/subjective-anger-and-overt-aggression-in-psychiatric-outpatients
#19
Timothy Genovese, Kristy Dalrymple, Iwona Chelminski, Mark Zimmerman
BACKGROUND: The attention given to anger and aggression in psychiatric patients pales in comparison to the attention given to depression and anxiety. Most studies have focused on a limited number of psychiatric disorders, and results have been inconsistent. The present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project sought to replicate and extend prior findings examining which psychiatric disorders and demographic characteristics were independently associated with elevated levels of anger and aggression...
October 17, 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27809643/the-evaluation-of-anxiety-and-panic-agarophobia-scores-in-patients-with-benign-paroxysmal-positional-vertigo-on-initial-presentation-and-at-the-follow-up-visit
#20
Serif Samil Kahraman, Cengiz Arli, Umit Sertan Copoglu, Mehmet Hanifi Kokacya, Sait Colak
CONCLUSION: Patients with BPPV experienced short but intense anxiety and/or panic disorder, especially at the initial visit, but most patients recovered without medication with successful treatment. OBJECTIVE: Recent studies have shown that people with dizziness report some psychological problems such as panic and agoraphobia and anxiety. The aim of this study was to evaluate anxiety and panic agorophobia levels in patients with benign paroxysmal positional vertigo on initial presentation and at the follow-up visit and compare the scores with the control group...
November 4, 2016: Acta Oto-laryngologica
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