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Sophie Bischoff, Gesine Wieder, Franziska Einsle, Moritz B Petzold, Christiane Janßen, Jennifer L M Mumm, Hans-Ulrich Wittchen, Thomas Fydrich, Jens Plag, Andreas Ströhle
Exposure-based Cognitive Behavioral Therapy (eb-CBT) represents the most evidence-based psychotherapeutic approach in anxiety disorders. However, its efficacy may be limited by a delay in onset of action and a substantial number of patients does not respond sufficiently to treatment. In this context, aerobic exercise was found to be effective in reducing clinical anxiety as well as to improve (elements of) disorder-specific CBT in some mental disorders. We therefore investigated the effect of aerobic exercise supplementary to an eb-CBT in panic disorder and agoraphobia (PD/AG)...
March 5, 2018: Journal of Psychiatric Research
Julia Wendt, Alfons O Hamm, Christiane A Pané-Farré, Julian F Thayer, Alexander Gerlach, Andrew T Gloster, Thomas Lang, Sylvia Helbig-Lang, Paul Pauli, Thomas Fydrich, Andreas Ströhle, Tilo Kircher, Volker Arolt, Jürgen Deckert, Hans-Ulrich Wittchen, Jan Richter
No abstract text is available yet for this article.
March 13, 2018: Psychotherapy and Psychosomatics
B Gulpers, A Lugtenburg, M Zuidersma, F R J Verhey, R C Oude Voshaar
BACKGROUND: Anxiety possibly interferes with executive functioning, although most studies rely on anxiety symptoms or lack control for comorbid depression. The objective of the present study is to examine the association between executive functioning and (individual) anxiety disorders with ak,ld without controlling for depression. METHOD: Generalized anxiety disorder (GAD), panic disorder with and without agoraphobia, agoraphobia, social phobia, as well as depressive disorder according to DSM-IV criteria were assessed with the Mini International Neuropsychiatric Interview in 82,360 community-dwelling people participating in the Lifelines cohort...
February 17, 2018: Journal of Affective Disorders
M Dold, L Bartova, J Mendlewicz, D Souery, A Serretti, S Porcelli, J Zohar, S Montgomery, S Kasper
OBJECTIVE: This multicenter, multinational, cross-sectional study aimed to investigate clinical characteristics and treatment outcomes associated with augmentation/combination treatment strategies in major depressive disorder (MDD). METHOD: Sociodemographic, clinical, and treatment features of 1410 adult MDD patients were compared between MDD patients treated with monotherapy and augmentation/combination medication using descriptive statistics, analyses of covariance (ancova), and Spearman's correlation analyses...
February 28, 2018: Acta Psychiatrica Scandinavica
Luana D Laurito, Carla P Loureiro, Rafaela V Dias, Paula Vigne, Gabriela B de Menezes, Rafael C Freire, Ulrich Stangier, Leonardo F Fontenelle
We investigated the rates of current and past benzodiazepine (BZD) use in a sample of 102 subjects attending specialized anxiety disorder clinics, including panic disorder (PD; N = 36), social anxiety disorder (SAD; N = 28) and obsessive-compulsive disorder (OCD; N = 38) patients. Almost 56% of the entire sample was using BZDs at the moment of the assessment, and 74.5% described having used them at some point during their lifetimes. The duration of psychiatric treatment and a lifetime history of PD, but not any other "transdiagnostic" measure of severity (such as the Panic and Agoraphobia Scale, the Social Phobia Inventory, the Dimensional Obsessive-Compulsive Scale, the Anxiety Sensitivity Index-36, and the Beck Inventories) were independent risk factors for current prescription of BZDs...
February 9, 2018: Psychiatry Research
Mariana B de Matos, Christian L de Mola, Jéssica P Trettim, Karen Jansen, Ricardo A da Silva, Luciano D de Mattos Souza, Liliane da Costa Ores, Mariane L Molina, Fernanda T Coelho, Ricardo T Pinheiro, Luciana de A Quevedo
OBJECTIVE: To evaluate the association between abuse of and dependence on different psychoactive substances and the presence of anxiety disorders in a sample of young adults from a city in southern Brazil. METHODS: Between 2007 and 2009, we carried out a cross-sectional, population-based study of individuals aged 18-24 years who lived in Pelotas, a city in southern Brazil. We evaluated anxiety disorders using the Mini International Neuropsychiatric Interview 5.0 (MINI), and use of psychoactive substances with the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST 2...
February 15, 2018: Revista Brasileira de Psiquiatria
Peter G van der Velden, Mauro Pecoraro, Mijke S Houwerzijl, Erik van der Meulen
Whistleblowers play a very important and indispensable role in society and health care sector, but their act may elicit retaliation and other negative effects, which may impact their mental health. The main aim of the present comparative study is to assess to what extent whistleblowers ( N = 27) more often suffer from severe mental health problems than other population-based groups in the Netherlands, i.e., matched controls ( N = 135), cancer patients ( N = 130), persons with (partial) work disabilities ( N = 194), physically "healthy" persons ( N = 200), and general population ( N = 1026), using the 36-Item Short-Form Health Survey scales (for general mental health) and the Symptom Checklist-90-Revised scales (for specific mental health problems: depression, anxiety, agoraphobia, interpersonal sensitivity and distrust, and sleeping problems)...
January 1, 2018: Psychological Reports
Justin S Feinstein, Sahib S Khalsa, Hung-Wen Yeh, Colleen Wohlrab, W Kyle Simmons, Murray B Stein, Martin P Paulus
Floatation-REST (Reduced Environmental Stimulation Therapy) reduces sensory input to the nervous system through the act of floating supine in a pool of water saturated with Epsom salt. The float experience is calibrated so that sensory signals from visual, auditory, olfactory, gustatory, thermal, tactile, vestibular, gravitational and proprioceptive channels are minimized, as is most movement and speech. This open-label study aimed to examine whether Floatation-REST would attenuate symptoms of anxiety, stress, and depression in a clinical sample...
2018: PloS One
Susann Wichmann, Stefan R Bornstein, Thomas Lorenz, Katja Petrowski
This study tested whether the hormonal stress response to the DEX-CRH test may be predictive of the psychotherapy success for panic disorder (PD). Thirty-four patients diagnosed either with agoraphobia with PD or PD without agoraphobia were subjected to cognitive behavioural therapy (CBT). Patients (pre-therapy) and healthy volunteers were exposed to the DEX-CRH test. Blood samples were taken for cortisol and adrenocorticotropic hormone (ACTH) assessment. Established panic-specific questionnaires were handed out for the pre-therapy and post-therapy evaluation of disease severity (with reference to panic beliefs and agoraphobic cognitions, fear of bodily sensations, agoraphobic avoidance behaviour)...
February 2, 2018: Translational Psychiatry
A Ströhle, T Fydrich
According to the Federal Healthcare Survey (Bundesgesundheitssurvey), approximately 15% of the German population fulfil the diagnostic criteria for at least one anxiety disorder within (any) 1 year. Women are affected approximately twice as often as men. The study by the Robert Koch Institute included the systematic assessment of panic disorder, agoraphobia, generalized anxiety disorder, social anxiety disorder and specific phobias; therefore, the question for both those affected and the treating therapist is "anxiety disorders: which psychotherapy for whom?" is of great clinical and healthcare political importance...
January 30, 2018: Der Nervenarzt
Petrus J W Naudé, Annelieke M Roest, Dan J Stein, Peter de Jonge, Bennard Doornbos
Objectives - Growing evidence indicates that inflammatory processes may play a role in the pathogenesis of anxiety disorders. Nevertheless, much remains to be learned about the involvement of inflammation, including C-reactive protein (CRP), in specific anxiety disorders. This study examines the relation between anxiety disorders and CRP. Methods - Associations of serum CRP with anxiety disorders were determined in a large population study (n = 54,326 participants, mean age = 47 years; 59% female), the LifeLines cohort...
January 29, 2018: World Journal of Biological Psychiatry
M Sadetski, M L Tourinho Moretto, R P Correia de Araujo, J F de Carvalho
Objectives To detect the frequency of psychological alterations in primary antiphospholipid syndrome patients. Methods Thirty-six primary antiphospholipid syndrome patients were analyzed by a psychological interview using a standard protocol and review of medical charts. Clinical manifestations, associated comorbidities, antiphospholipid antibodies, and treatment were also evaluated. Results The mean age was 44.2 ± 10.8 years, 29 (80%) were women and 29 (80%) were of Caucasian race. The mean duration of disease was 7...
January 1, 2018: Lupus
S Ogawa, M Kondo, K Ino, T Ii, R Imai, T A Furukawa, T Akechi
OBJECTIVE: To examine the relationship of fear of fear and broad dimensions of psychopathology in panic disorder with agoraphobia over the course of cognitive behavioural therapy in Japan. METHODS: A total of 177 Japanese patients with panic disorder with agoraphobia were treated with group cognitive behavioural therapy between 2001 and 2015. We examined associations between the change scores in Agoraphobic Cognitions Questionnaire or Body Sensations Questionnaire and the changes in subscales of Symptom Checklist-90 Revised during cognitive behavioural therapy controlling the change in panic disorder severity using multiple regression analysis...
December 2017: East Asian Archives of Psychiatry: Official Journal of the Hong Kong College of Psychiatrists
Jennifer Glaus, Roland von Känel, Aurélie M Lasserre, Marie-Pierre F Strippoli, Caroline L Vandeleur, Enrique Castelao, Mehdi Gholam-Rezaee, Ciro Marangoni, En-Young N Wagner, Pedro Marques-Vidal, Gérard Waeber, Peter Vollenweider, Martin Preisig, Kathleen R Merikangas
BACKGROUND: Although there has been abundant research on chronic low-grade inflammation as a potential mechanism underlying the link between mood disorders and cardiovascular risk, less is known about the role of inflammatory factors and anxiety disorders. The aim of this paper is to evaluate the bi-directional associations between inflammatory markers including interleukin (IL)-6, tumor necrosis factor (TNF)-α, and high sensitivity C-reactive protein (hsCRP) with anxiety disorders and its subgroups...
December 15, 2017: Depression and Anxiety
John R Keefe, Barbara L Milrod, Robert Gallop, Jacques P Barber, Dianne L Chambless
BACKGROUND: No studies of psychotherapies for panic disorder (PD) have examined effects on comorbid personality disorders (PersD), yet half such patients have a PersD. METHODS: In a randomized trial for PD with and without agoraphobia comparing Cognitive-Behavioral Therapy (CBT) and Panic-Focused Psychodynamic Psychotherapy (PFPP), PersD was assessed pre-to-post treatment with the Structured Clinical Interview for the Diagnosis of Axis-II Disorders (SCID-II). For patients completing therapy (n = 118, 54 with PersD), covariance between panic and SCID-II criteria improvements was analyzed...
March 2018: Depression and Anxiety
Marina Christoforou, José Andrés Sáez Fonseca, Elias Tsakanikos
BACKGROUND: Despite the large body of literature demonstrating the effectiveness of cognitive behavioral treatments for agoraphobia, many patients remain untreated because of various barriers to treatment. Web-based and mobile-based interventions targeting agoraphobia may provide a solution to this problem, but there is a lack of research investigating the efficacy of such interventions. OBJECTIVE: The objective of our study was to evaluate for the first time the effectiveness of a self-guided mobile-based intervention primarily targeting agoraphobic symptoms, with respect to a generic mobile app targeting anxiety...
November 24, 2017: Journal of Medical Internet Research
Lisa M McTeague, Marie-Claude Laplante, Hailey W Bulls, Joshua R Shumen, Peter J Lang, Andreas Keil
BACKGROUND: Theories of aberrant attentional processing in social anxiety, and anxiety disorders more broadly, have postulated an initial hypervigilance or facilitation to clinically relevant threats and consequent defensive avoidance. However, existing objective measurements utilized to explore this phenomenon lack the resolution to elucidate attentional dynamics, particularly covert influences. METHODS: We utilized a continuous measure of visuocortical engagement, the steady-state visual evoked potential in response to naturalistic angry, fearful, happy, and neutral facial expressions...
October 13, 2017: Biological Psychiatry
Alexandra S Creighton, Tanya E Davison, David W Kissane
BACKGROUND: Little is known about anxiety in aged care populations, despite its increase in this frail population. This study investigated the prevalence, recording, and treatment rate of anxiety disorders among aged care residents. METHODS: A cross-sectional, observational design was used to assess 180 elderly residents from 12 aged care facilities in Melbourne, Australia. Participants were assessed for threshold and subthreshold anxiety disorders and comorbid depression using the MINI for DSM-5...
November 10, 2017: Journal of Affective Disorders
Béatrice Ithier
No abstract text is available yet for this article.
December 2017: International Journal of Psycho-analysis
John David Eun, Diana Paksarian, Jian-Ping He, Kathleen Ries Merikangas
PURPOSE: We examined associations between parenting style and past-year mental disorders in a nationally representative cross-sectional survey of US adolescents and whether the associations differed by adolescent demographic characteristics. METHODS: The sample included 6483 adolescents aged 13-18 years who were interviewed for a full range of DSM-IV mental disorders. Parenting style was assessed by adolescent-reported maternal and paternal care and control using items from the Parental Bonding Instrument...
November 6, 2017: Social Psychiatry and Psychiatric Epidemiology
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