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https://www.readbyqxmd.com/read/29775542/exercise-and-circulating-bdnf-mechanisms-of-release-and-implications-for-the-design-of-exercise-interventions
#1
Jeremy James Walsh, Michael E Tschakovsky
Engagement in regular bouts of exercise confers numerous positive effects on brain health across the lifespan. Acute bouts of exercise transiently improve cognitive function, while long-term exercise training stimulates brain plasticity, improves brain function, and helps to stave off neurological disease. The action of brain-derived neurotrophic factor (BDNF) is a candidate mechanism underlying these exercise-induced benefits and is the subject of considerable attention in the exercise-brain health literature...
May 18, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29774489/the-role-of-lifestyle-in-male-infertility-diet-physical-activity-and-body-habitus
#2
REVIEW
Russell P Hayden, Ryan Flannigan, Peter N Schlegel
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29768264/opportunities-and-challenges-in-global-perinatal-research
#3
Jessica Duby, Renee Sharma, Zulfiqar A Bhutta
BACKGROUND: The global plight of stillbirths and neonatal mortality is concentrated in low- and middle-income countries. The ambitious targets introduced by the World Health Organization in the Every Newborn Action Plan demand a commitment to research that promotes equitable perinatal outcomes. OBJECTIVES: The aim of this review was to understand the opportunities for global perinatal research and the accompanying challenges. METHODS: We conducted a literature search to identify research prioritization exercises from 2014 to 2018 pertaining to global perinatal health...
May 16, 2018: Neonatology
https://www.readbyqxmd.com/read/29764678/re-engaging-with-places-understanding-bio-geo-graphical-disruption-and-flow-in-adult-brain-injury-survivors
#4
Louise Meijering, Nicky Theunissen, Ant T Lettinga
Acquired Brain Injury (ABI) is one of the most common causes of disability and death in adults worldwide. After a period of rehabilitation, many ABI survivors still face complex mind/body conditions when they try to take up their former life again. Besides lasting visible impairments such as weakness and loss of body balance, there are often less obvious disabilities such as extreme fatigue, hypersensitivity for stimuli, memory, concentration and attention problems or personality changes. The aim of this paper is to understand how ABI survivors and their significant others renegotiate their engagements with everyday places, using the concepts of bio-geo-graphical disruption and flow...
May 5, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29760784/practical-guidance-for-the-management-of-iron-deficiency-in-patients-with-inflammatory-bowel-disease
#5
REVIEW
Dorothea Niepel, Thomas Klag, Nisar P Malek, Jan Wehkamp
Iron deficiency or iron deficiency anemia (IDA) are some of the most common systemic complications of inflammatory bowel diseases (IBD). Symptoms such as fatigue, reduced ability to concentrate and reduced exercise tolerance can mimic common symptoms of IBD and can therefore easily be overseen. Furthermore, clinicians tend to see mild to moderate anemia as an inevitable accompaniment of IBD that is sufficiently explained by the underlying disease and does not require further workup. But in contrast to these clinical routines, current guidelines recommend that any degree of anemia in patients with IBD should be further evaluated and treated...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29757444/physical-activity-sedentary-time-and-associated-factors-in-recipients-of-solid-organ-transplantation
#6
Edwin J van Adrichem, Rienk Dekker, Wim P Krijnen, Erik A M Verschuuren, Pieter U Dijkstra, Cees P van der Schans
Background: Short-term survival after solid-organ transplantation has substantially improved, and the focus has shifted to long-term survival, including the role of physical activity (PA). Knowledge about PA and sedentary time in recipients of solid-organ transplantation is limited, and identification of the levels and associated factors is necessary for intervention development. Objective: The objectives of this study were to investigate the level of PA and sedentary time in recipients of solid-organ transplantation and to identify factors associated with these behaviors...
May 10, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29754811/integrated-exposure-therapy-and-exercise-reduces-fear-of-falling-and-avoidance-in-older-adults-a-randomized-pilot-study
#7
Julie Loebach Wetherell, Emily S Bower, Kristen Johnson, Douglas G Chang, Samuel R Ward, Andrew J Petkus
OBJECTIVES: To evaluate the safety and acceptability of a novel 8-week intervention integrating exercise, exposure therapy, cognitive restructuring, and a home safety evaluation, conducted by a physical therapist, in reducing fear of falling and activity avoidance. To collect preliminary evidence of efficacy. DESIGN: Randomized pilot study comparing the intervention to time- and attention-equivalent fall prevention education. SETTING: Participants' homes...
April 12, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29751661/effects-of-2-year-cognitive%C3%A2-motor-dual-task-training-on-cognitive-function-and-motor-ability-in-healthy-elderly-people-a-pilot-study
#8
Emiko Morita, Hisayo Yokoyama, Daiki Imai, Ryosuke Takeda, Akemi Ota, Eriko Kawai, Yuta Suzuki, Kazunobu Okazaki
We aimed to examine the effect of 2-year cognitive⁻motor dual-task (DT) training on cognitive functions and motor ability of healthy elderly people without marked cognitive impairment. From the 25 participants of our 12-week DT trial conducted in 2014, we recruited 8 subjects who voluntarily participated in a new DT training program once a week for 2 years (exercise (EX) group). Their cognitive functions were evaluated by the Modified Mini-Mental State (3MS) examination and the Trail Making Test, and results were compared with those of the 11 subjects who discontinued the training and did not perform any types of exercise for 2 years (non-exercise (NO) group)...
May 11, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29746823/behavior-change-intervention-targeting-physical-function-walking-and-disability-after-dysvascular-amputation-a-randomized-controlled-pilot-trial
#9
Cory L Christiansen, Matthew J Miller, Amanda M Murray, Ryan O Stephenson, Jennifer E Stevens-Lapsley, William R Hiatt, Margaret L Schenkman
OBJECTIVE: To determine preliminary efficacy of a home-based behavior-change intervention designed to promote exercise, walking activity, and disease self-management. DESIGN: A single-blind, randomized controlled pilot trial. SETTING: One Veteran's Administration (VA) and two regional medical centers. PARTICIPANTS: Thirty-eight participants randomized to behavior-change intervention (INT; n=19) or attention control (CTL; n=19) group...
May 7, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29741205/protocol-for-a-randomized-controlled-trial-of-piano-training-on-cognitive-and-psychosocial-outcomes
#10
Jennifer Bugos
Age-related cognitive decline and cognitive impairment represent the fastest growing health epidemic worldwide among those over 60. There is a critical need to identify effective and novel complex cognitive interventions to promote successful aging. Since piano training engages cognitive and bimanual sensorimotor processing, we hypothesize that piano training may serve as an effective cognitive intervention, as it requires sustained attention and engages an executive network that supports generalized cognition and emotional control...
May 9, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29738032/does-high-intensity-exercise-affects-irisin-plasma-levels-in-hemodialysis-patients-a-pilot-study
#11
Marta Gormicho Boavida Marques Esgalhado, Milena Barcza Stockler-Pinto, Ludmila Ferreira Medeiros de França Cardozo, Jorge Eduardo Barboza, Denise Mafra
BACKGROUND: Irisin is a recently identified exercise-induced hormone that stimulates the "browning" of the white adipose tissue, at least in mice. In chronic kidney disease (CKD) patients, irisin regulation is not fully understood, and little attention has been given to the effects of exercise on irisin levels in these patients. The purpose of this study was to assess the effects of high intensity exercise on irisin plasma levels in CKD patients under hemodialysis (HD). METHODS: Fifteen HD patients (5 men, 44...
April 23, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29729687/exercise-effects-on-cognitive-functioning-in-young-adults-with-first-episode-psychosis-fitforlife
#12
Mats Hallgren, Maria Skott, Örjan Ekblom, Joseph Firth, Adrian Schembri, Yvonne Forsell
BACKGROUND: Exercise has mood-enhancing effects and can improve cognitive functioning, but the effects in first-episode psychosis (FEP) remain understudied. We examined the feasibility and cognitive effects of exercise in FEP. METHOD: Multi-center, open-label intervention study. Ninety-one outpatients with FEP (mean age = 30 years, 65% male) received usual care plus a 12-week supervised circuit-training program, consisting of high-volume resistance exercises, aerobic training, and stretching...
May 6, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29727710/evidence-for-a-long-term-protection-of-wheel-running-exercise-against-cocaine-psychomotor-sensitization-in-adolescent-but-not-in-adult-mice
#13
Louis-Ferdinand Lespine, Ezio Tirelli
Rodents housed with a running wheel can exhibit attenuated cocaine seeking and cocaine-induced psychomotor activation. However, the longevity of such a protection and the influence of the developmental stage during which exercise is displayed received little attention. Here, females and males C57BL/6 J mice, aged 28 (adolescents) or 77 (adults) days were housed with (n = 56) or without (n = 28) a running wheel. After 3 weeks in these conditions, half of the exercised mice were deprived of their wheel (n = 28) whereas the other half and the sedentary mice were kept in their respective environments...
May 1, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29725875/obesity-and-migraine-in-childhood
#14
REVIEW
Tal Eidlitz Markus, Irene Toldo
PURPOSE OF REVIEW: The purpose of this work was to review the current literature on the epidemiology and pathophysiology of pediatric obesity and migraine, underlying pathogenic mechanisms that may explain the association between the two disorders, and the effects of treatment. RECENT FINDINGS: In children and adolescents, the bulk of the available data support an association between obesity and headache disorders in general, though a small number of studies contradict these findings...
May 3, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29723066/the-effectiveness-of-web-based-patient-education-and-action-and-coping-plans-as-an-adjunct-to-patient-treatment-in-physiotherapy-a-randomized-controlled-trial
#15
Heather Clark, Sandra Bassett, Richard Siegert
OBJECTIVE: The study investigated: (1) the effect of combining web-based patient education (WBPE) with action and coping plans on patients' adherence to physiotherapy and their subsequent functional outcomes; and (2) the participants' satisfaction with the WBPE program. METHODS: One hundred and eight participants enrolled in this 8-week two group randomized controlled trial. They were allocated to either the WBPE planning group or the attention-control group. The WBPE group made action and coping plans and were familiarized with their web-based program...
May 3, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29722584/no-difference-between-the-effects-of-supplementing-with-soy-protein-versus-animal-protein-on-gains-in-muscle-mass-and-strength-in-response-to-resistance-exercise
#16
Mark Messina, Heidi Lynch, Jared M Dickinson, Katharine E Reed
Much attention has been given to determining the influence of total protein intake and protein source on gains in lean body mass (LBM) and strength in response to resistance exercise training (RET). Acute studies indicate that whey protein, likely related to its higher leucine content, stimulates muscle protein synthesis (MPS) to a greater extent than proteins such as soy and casein. Less clear is the extent to which the type of protein supplemented impacts strength and LBM in longer term studies (≥6 weeks)...
May 3, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29717392/arterial-distensibility-physical-activity-and-the-metabolic-syndrome
#17
REVIEW
Francesca Saladini, Paolo Palatini
PURPOSE OF REVIEW: Metabolic syndrome (MetS), a cluster of risk factors including central obesity, metabolic abnormalities, and arterial hypertension, is a well-known determinant of arterial wall remodeling and stiffening. The mechanisms whereby MetS promotes arterial stiffening include increased sympathetic activity with the associated fast heart rate, enhanced activity of the renin-angiotensin-aldosterone system, increased production of inflammatory cytokines and reactive oxygen species, and reduction of nitric oxide availability...
May 1, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29714565/rethinking-the-clinically-based-thresholds-of-transcelerate-biopharma-for-risk-based-monitoring
#18
Richard C Zink, Anastasia Dmitrienko, Alex Dmitrienko
BACKGROUND: The quality of data from clinical trials has received a great deal of attention in recent years. Of central importance is the need to protect the well-being of study participants and maintain the integrity of final analysis results. However, traditional approaches to assess data quality have come under increased scrutiny as providing little benefit for the substantial cost. Numerous regulatory guidance documents and industry position papers have described risk-based approaches to identify quality and safety issues...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29707168/leadership-and-post-traumatic-stress-disorder-are-soldiers-perceptions-of-organizational-justice-during-deployment-protective
#19
Andreas F Elrond, Annie Høgh, Søren B Andersen
Background : Soldiers' perception of leadership during military deployment has gained research attention as a potentially modifiable factor to buffer against the development of postdeployment post-traumatic stress disorder (PTSD). Within nonmilitary research, the organizational justice (OJ) framework, i.e. distributive justice, procedural justice (PJ) and interactional justice (IJ), has been found to relate to mental health outcomes. Aspects of OJ may, therefore, be protective against PTSD. Objectives : We examined the prospective relationship between aspects of OJ, namely the perceptions of PJ and IJ by subordinate soldiers without leadership obligations in relationship to immediate superiors and PTSD...
2018: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29705888/a-physical-exercise-program-using-music-supported-video-based-training-in-older-adults-in-nursing-homes-suffering-from-dementia-a-feasibility-study
#20
Joke Spildooren, Ite Speetjens, Johan Abrahams, Peter Feys, Annick Timmermans
BACKGROUND: Motivation towards an exercise program is higher in a small group setting in comparison to individual therapy. Due to attentional problems, group exercises are difficult for people with Alzheimer disease (AD). This study evaluates the feasibility of a music-supported video-based group exercise program in older adults suffering from AD. METHODS: Five participants with moderate AD were recruited from a nursing home. A progressive physical exercise program using a video-based training with musical accompaniment was performed and digitally recorded to investigate the adherence and performed accuracy of the exercises...
April 28, 2018: Aging Clinical and Experimental Research
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