keyword
https://read.qxmd.com/read/38534716/assessment-of-colistin-heteroresistance-among-multidrug-resistant-klebsiella-pneumoniae-isolated-from-intensive-care-patients-in-europe
#1
JOURNAL ARTICLE
Anouk J M M Braspenning, Sahaya Glingston Rajakani, Adwoa Sey, Mariem El Bounja, Christine Lammens, Youri Glupczynski, Surbhi Malhotra-Kumar
Heteroresistance (HR) to colistin is especially concerning in settings where multi-drug-resistant (MDR) K. pneumoniae are prevalent and empiric use of colistin might lead to treatment failures. This study aimed to assess the frequency of occurrence of colistin HR (CHR) among (MDR) K. pneumoniae ( n = 676) isolated from patients hospitalized in 13 intensive care units (ICUs) in six European countries in a clinical trial assessing the impact of decolonization strategies. All isolates were whole-genome-sequenced and studied for in vitro colistin susceptibility...
March 20, 2024: Antibiotics
https://read.qxmd.com/read/38524719/diagnosis-and-prevention-of-periprosthetic-joint-infections-by-staphylococcus-aureus-after-hip-fracture-a-systematic-review-of-the-literature
#2
JOURNAL ARTICLE
Bianca Gabriella de Oliveira, Victor Hugo Ruis da Costa, Igor Rodrigues Gama, Murilo Halberstadt Beskow, Elisson Rafael Silva Dos Santos
Hip arthroplasties are surgical procedures widely performed all over the world, seeking to return functionality, relieve pain, and improve the quality of life of patients affected by osteoarthritis, femoral neck fractures, osteonecrosis of the femoral head, among other etiologies. Periprosthetic joint infections are one of the most feared complications due to the high associated morbidity and mortality, with a high number of pathogens that may be associated with its etiology. The aim of the present study was to analyze aspects correlated with the occurrence of infection, diagnosis and prevention of periprosthetic joint infections in the hip associated with Staphylococcus aureus after corrective surgery for hip fractures...
February 2024: Revista Brasileira de Ortopedia
https://read.qxmd.com/read/38510358/does-the-south-african-government-have-a-duty-to-fund-influenza-vaccination-of-adults-65%C3%A2-years-and-older
#3
JOURNAL ARTICLE
Ruach Sarangarajan, Cornelius Ewuoso
In this paper, we draw on the thinking about solidarity, reciprocity and distributive justice grounded in Afro-communitarian ethics from the Global South to argue for institutions, particularly the South African (SA) government, have a prima facie duty to foster influenza vaccine uptake for adults 65 years and older. Although we focus specifically on the South African government to defend our position, we believe that our argument extends to all governments. Notably, these duties are that the SA government ought to make influenza vaccines freely available for the older adult in both the public and private health facilities, provided financial allocation and their extant relationships allow for this...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38498166/decolonization-strategies-against-multidrug-resistant-organisms-in-the-icu
#4
EDITORIAL
Pedro Póvoa, Paula Ramirez, Stijn Blot
No abstract text is available yet for this article.
March 18, 2024: Intensive Care Medicine
https://read.qxmd.com/read/38482592/a-culturally-humble-approach-to-designing-a-sports-based-youth-development-program-with-african-australian-community
#5
JOURNAL ARTICLE
Rachel Goff, Patrick O'Keeffe, Abraham Kuol, Rob Cunningham, Ronnie Egan, Bawa Kuyini, Robyn Martin
This article draws on the concept of cultural humility, to describe and analyze a decolonizing approach to co-designing a primary prevention basketball program for young African-Australian people in Melbourne, Australia. We explore the potential for genuine collaboration and power-sharing with a culturally diverse community through collaboratively developing the co-design process and resultant program design. This article highlights the central role of UBUNTU in the co-design process, prioritizing African ways of knowing, being, and doing within a Westernized social work and design context...
March 14, 2024: Qualitative Health Research
https://read.qxmd.com/read/38478462/long-and-short-term-effects-of-fecal-microbiota-transplantation-on-antibiotic-resistance-genes-results-from-a-randomized-placebo-controlled-trial
#6
RANDOMIZED CONTROLLED TRIAL
Armin Rashidi, Maryam Ebadi, Tauseef Ur Rehman, Heba Elhusseini, David Kazadi, Hossam Halaweish, Mohammad H Khan, Andrea Hoeschen, Qing Cao, Xianghua Luo, Amanda J Kabage, Sharon Lopez, Shernan G Holtan, Daniel J Weisdorf, Chang Liu, Satoshi Ishii, Alexander Khoruts, Christopher Staley
In small series, third-party fecal microbiota transplantation (FMT) has been successful in decolonizing the gut from clinically relevant antibiotic resistance genes (ARGs). Less is known about the short- and long-term effects of FMT on larger panels of ARGs. We analyzed 226 pre- and post-treatment stool samples from a randomized placebo-controlled trial of FMT in 100 patients undergoing allogeneic hematopoietic cell transplantation or receiving anti-leukemia induction chemotherapy for 47 ARGs. These patients have heavy antibiotic exposure and a high incidence of colonization with multidrug-resistant organisms...
2024: Gut Microbes
https://read.qxmd.com/read/38475516/preserving-ethnoveterinary-medicine-evm-along-the-transhumance-routes-in-southwestern-angola-synergies-between-international-cooperation-and-academic-research
#7
JOURNAL ARTICLE
David Solazzo, Maria Vittoria Moretti, José J Tchamba, Marina Filomena Francisco Rafael, Matteo Tonini, Gelsomina Fico, Txaran Basterrecea, Silvano Levi, Lorenzo Marini, Piero Bruschi
This study delves into the ethnoveterinary medicine (EVM) practiced by pastoralists along the transhumance routes in southwestern Angola. Within the framework of three cooperation projects, we conducted 434 interviews, collecting information on 89 taxa used for treating 16 livestock diseases. The most cited species was Ptaeroxylon obliquum (132 citations), followed by Salvadora persica (59) and Elaeodendron transvaalense (49). Contagious bovine pleuropneumonia (CBPP) was the disease most cited (223 citations; 44 species), followed by wounds (95; 20) and Newcastle (86; 14)...
February 28, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38461969/efficacy-of-233-nm-led-far-uv-c-radiation-against-clinically-relevant-bacterial-strains-in-the-phase-2-step-2-in-vitro-test-on-basis-of-en-14561-and-on-an-epidermis-cell-model
#8
JOURNAL ARTICLE
Claudia Sicher, Nevin Opitz, Pia Elen Becker, Neysha Lobo Ploch, Johannes Schleusener, Michael Kneissl, Axel Kramer, Paula Zwicker
INTRODUCTION: Healthcare-acquired infections and overuse of antibiotics are a common problem. Rising emergence of antibiotic and antiseptic resistances requires new methods of microbial decontamination or decolonization as the use of far-UV-C radiation. METHODS: The microbicidal efficacy of UV-C radiation (222 nm, 233 nm, 254 nm) was determined in a quantitative carrier test and on a 3D-epidermis model against Staphylococcus (S.) aureus, S. epidermidis, S. haemolyticus, S...
March 8, 2024: Microbes and Infection
https://read.qxmd.com/read/38461914/radiologists-role-in-decolonizing-global-health
#9
REVIEW
Farouk Dako, Toma S Omofoye, John Scheel
The colonial origins and power imbalances between western high-income countries (HICs) and low and middle-income countries (LMICs) are barriers to self-reliance and sustained structural improvements to healthcare systems. Radiologists working in global health (Global Radiologists) are tasked with improving the state of imaging in LMICs while mitigating the effects of colonial structures and processes. To accomplish this, we need to be aware of factors such as colonialism, neocolonialism, parachute research, and brain drain that contribute to global health inequities...
March 8, 2024: Journal of the American College of Radiology: JACR
https://read.qxmd.com/read/38460550/monitoring-staphylococcus-aureus-nasal-colonization-murine-model-using-a-bioluminescent-methicillin-resistant-s-aureus-mrsa
#10
JOURNAL ARTICLE
Juliana G da Silva, Juliana Pc Boechat, Bruno Dj Silva, Rodrigo Müller, José Pm Senna
Staphylococcus aureus nasal carriage is considered a risk factor for infections, and the development of nasal decolonization strategies is highly relevant. Despite they are not naturally colonized by Staphylococcus , mice are a good model for S. aureus nasal colonization. Murine models are easy to manipulate, and inter-laboratory reproducibility makes them suitable for nasal colonization studies. Strategies using bioluminescent bacteria allow for the monitoring of infection over time without the need to sacrifice animals for bacterial quantification...
March 9, 2024: Laboratory Animals
https://read.qxmd.com/read/38451641/bewilderment-aquilombar-and-the-antimanicolonial-three-ideas-to-radicalize-brazilian-psychiatric-reform
#11
JOURNAL ARTICLE
Emiliano de Camargo David, Maria Cristina Gonçalves Vicentin, Lia Vainer Schucman
This article is part of a study aimed to map antiracist knowledge and practices in mental health by monitoring the practices of three collectives of professionals working in/with the psychosocial care network in the city of São Paulo, allowing us to characterize their intervention strategies. To contribute to the conceptualization of this article, through a review of the decolonial literature, three major ideas have been outlined that have allowed us to give substance to the decolonization of Psychiatric Reform: bewilderment, which, in dialogue with Achille Mbembe and Frantz Fanon, invites us to affirm madness and blackness without, however, establishing fixations; the antimanicolonial, which occurs in the promotion of the free and countercultural exercise of imagining diasporas, in light of that proposed by Édouard Glissant, Paul Gilroy, and Lélia Gonzales regarding an Atlantic (de)orientation in which elements of the black diaspora and Latin America can re-signify blackness and unreason; and aquilombar, as a liberatory praxis whose genesis lies in the quilombos as a living metaphor for the radicalisation of relationships in differences, based on Abdias do Nascimento's quilombismo, Clóvis Moura's quilombagem, Beatriz Nascimento's (k)quilombo, and Mariléa de Almeida's devir quilomba...
March 2024: Ciência & Saúde Coletiva
https://read.qxmd.com/read/38440877/impact-of-universal-chlorhexidine-bathing-with-or-without-covid-19-intensive-training-on-staff-and-resident-covid-19-case-rates-in-nursing-homes
#12
JOURNAL ARTICLE
Gabrielle M Gussin, Raveena D Singh, Shruti K Gohil, Raheeb Saavedra, Thomas T Tjoa, Kristine P Nguyen, Robert Pedroza, Joshua B Hsi, Kevin O'Brien, Chase Berman, Jessica Park, Emily A Hsi, Kimia Ghasemian, Avy Osalvo, Stephanie Chun, Emily Fonda, Susan S Huang
We evaluated whether universal chlorhexidine bathing (decolonization) with or without COVID-19 intensive training impacted COVID-19 rates in 63 nursing homes (NHs) during the 2020-2021 Fall/Winter surge. Decolonization was associated with a 43% lesser rise in staff case-rates ( P < .001) and a 52% lesser rise in resident case-rates ( P < .001) versus control.
March 5, 2024: Infection Control and Hospital Epidemiology
https://read.qxmd.com/read/38436256/re-framing-the-importance-of-group-b-streptococcus-as-a-gut-resident-pathobiont
#13
REVIEW
Joie Ling, Andrew J Hryckowian
Streptococcus agalactiae (Group B Streptococcus , GBS) is a Gram-positive bacterial species that causes disease in humans across the lifespan. While antibiotics are used to mitigate GBS infections, it is evident that antibiotics disrupt human microbiomes (which can predispose people to other diseases later in life), and antibiotic resistance in GBS is on the rise. Taken together, these unintended negative impacts of antibiotics highlight the need for precision approaches for minimizing GBS disease. One possible approach involves selectively depleting GBS in its commensal niches before it can cause disease at other body sites or be transmitted to at-risk individuals...
March 4, 2024: Infection and Immunity
https://read.qxmd.com/read/38435470/self-determination-in-global-health-practices-voices-from-the-global-south
#14
JOURNAL ARTICLE
Maureen Kesande, Jane Jere, Sandra I McCoy, Abel Wilson Walekhwa, Bongekile Esther Nkosi-Mjadu, Eunice Ndzerem-Shang
Despite the commendable progress made in addressing global health challenges and threats such as child mortality, HIV/AIDS, and Tuberculosis, many global health organizations still exhibit a Global North supremacy attitude, evidenced by their choice of leaders and executors of global health initiatives in low- and middle-income countries (LMICs). While efforts by the Global North to support global health practice in LMICs have led to economic development and advancement in locally led research, current global health practices tend to focus solely on intervention outcomes, often neglecting important systemic factors such as intellectual property ownership, sustainability, diversification of leadership roles, and national capacity development...
2024: Annals of Global Health
https://read.qxmd.com/read/38424491/best-practice-models-of-aged-care-implemented-for-first-nations-people-a-systematic-review-aligned-with-the-good-spirit-good-life-quality-of-life-principles
#15
JOURNAL ARTICLE
Caleb Rivers, Emma Haynes, Dina LoGiudice, Kate Smith, Dawn Bessarab
BACKGROUND: Aged-care programs that are based in First Nations worldviews are believed to translate to improved quality of life for First Nations Elders. First Nations perspectives of health and well-being incorporates social and cultural determinants in addition to traditional Western biomedical approaches. This is exemplified by the Good Spirit Good Life (GSGL) framework, which comprises 12 strength-based factors determined by First Nations Elders as constituting culturally appropriate ageing...
February 29, 2024: BMC Geriatrics
https://read.qxmd.com/read/38416126/hygiene-measures-and-decolonization-of-staphylococcus-aureus-made-simple-for-the-pediatric-practitioner
#16
JOURNAL ARTICLE
Fabien Cane, Klara M Posfay-Barbe, Laure F Pittet
No abstract text is available yet for this article.
February 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38402131/modifiable-preoperative-risk-factors-to-mitigate-postoperative-site-infection-following-pediatric-gastrostomy
#17
JOURNAL ARTICLE
Shelby R Sferra, Sara Donnelly, Sandra Kabagambe, Erica M Fallon
PURPOSE: There are limited studies assessing modifiable preoperative risk factors for pediatric laparoscopic gastrostomy tubes (LGT) and percutaneous endoscopic gastrostomy (PEG) tubes. We sought to evaluate the effect of demographics and surgical/infectious history on the superficial infection rate following gastrostomy tube (GT) placement. METHODS: After IRB approval, we conducted a single-institution retrospective cohort study from 2015 to 2021 of pediatric patients undergoing LGT or PEG tube...
February 13, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38399456/in-vitro-and-ex-vivo-investigation-of-the-antibacterial-effects-of-methylene-blue-against-methicillin-resistant-staphylococcus-aureus
#18
JOURNAL ARTICLE
Deniz Gazel, Mehmet Erinmez, Gönenç Çalışkantürk, Khandakar A S M Saadat
Methylene blue (MB) is a water-soluble dye that has a number of medical applications. Methicillin-resistant Staphylococcus aureus (MRSA) was selected as a subject for research due to the numerous serious clinical diseases it might cause and because there is a significant global resistance challenge. Our main goal was to determine and analyze the antibacterial effects of MB against S. aureus both in vitro and ex vivo to enhance treatment options. A total of 104 MRSA isolates recovered from various clinical specimens were included in this study...
February 13, 2024: Pharmaceuticals
https://read.qxmd.com/read/38385692/clinical-validation-of-loop-mediated-isothermal-amplification-for-the-detection-of-escherichia-coli-sequence-type-complex-131
#19
JOURNAL ARTICLE
Gisele Peirano, L Ricardo Castellanos, Yasufumi Matsumura, Ryan Chaffee, Daniel Castañeda-Mogollón, Dylan R Pillai, Johann D D Pitout
The dissemination of Escherichia coli multidrug-resistant (MDR) STc131 is related to its persistence in the human gastrointestinal tract as efficient gut colonizers. Infection and prevention measures are the cornerstones for preventing STc131 spread. Oral decolonization therapies that target ST131 are being developed. There are no rapid methods available to identify STc131 in human specimens. A loop-mediated isothermal amplification (LAMP) assay (named LAMP-ST131) was developed for the detection of STc131 on well-characterized E...
February 22, 2024: Journal of Clinical Microbiology
https://read.qxmd.com/read/38383948/understanding-african-american-help-seeking-for-romantic-relationships-advocacy-barriers-and-considerations
#20
JOURNAL ARTICLE
Aimee Hubbard, Steven Harris, Mary Dick, DasJohn McGee
African American couples experience greater levels of relationship distress than other racial/ethnic groups, but they are less likely to seek formal couple counseling. Existing literature highlights the importance of community support in the form of church, family, and friends. While the literature suggests that African Americans encounter unique barriers, we do not know how racism and discrimination impact the couple help-seeking process. This study seeks to address this gap and better understand unique barriers in the African American couple help-seeking (AACHS) process via a grounded theory-informed qualitative study...
February 21, 2024: Journal of Marital and Family Therapy
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