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https://www.readbyqxmd.com/read/28634380/late-onset-circulatory-collapse-and-continuous-positive-airway-pressure-are-useful-predictors-of-treatment-requiring-retinopathy-of-prematurity-a-9-year-retrospective-analysis
#1
Mitsuru Arima, Shoko Tsukamoto, Kohta Fujiwara, Miwa Murayama, Kanako Fujikawa, Koh-Hei Sonoda
Visual loss caused by retinopathy of prematurity (ROP) will be prevented if treatment-requiring ROP (TR-ROP) can be predicted. In this retrospective study including 418 infants with ≤32 weeks of gestational age (GA) and/or ≤1500 grams of birthweight, we attempted to identify useful predictors. We also examined the efficiency of significant predictors compared with existing predictive models, ROPScore and CHOP model. Multivariable logistic regression analyses supported the following factors were useful for predicting TR-ROP from all infants and infants with any ROP: GA (odds ratio [OR], 0...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28631494/a-study-on-preterm-births-during-2013-2015-shiraz-iran
#2
Elham Jaberi, Mirkazemi Roksana
Preterm birth is the leading cause of neonatal and infant mortality and a substantial portion of neonatal morbidities. The perinatal mortality and morbidity statistics in developing countries are inadequate. In this study, we assessed prevalence and health outcomes of preterm deliveries in tertiary care university hospitals. A retrospective study of hospital records of premature babies born in all the five governmental tertiary care settings during the time interval of 2013-2015 in Shiraz was conducted. Result of this study showed that there was an overall 127...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28629078/fluorescent-cds-pcl-hybrids-via-tartaric-acid-cds-cocatalyzed-polymerization
#3
Manqing Yan, Mingchen Zhou, Jing Chen, Tianlei Zhao, Longxiang Tang, Hong Bi
In this paper, the environment-friendly, water-soluble carbon dots (CDs) with stable photoluminescence (PL) have been prepared via the one-step pyrolysis of lotus leaf. Then the as-prepared CDs containing abundant hydroxylic and carboxylic groups were employed as cocatalyst with tartaric acid (TA) in ring-opening polymerization (ROP) of ε-caprolactone (ε-CL). The low-toxic organic acid TA, as main catalyst, was used to catalyze the ROP of ε-CL efficiently. The fluorescent CDs@PCL hybrids were obviously hydrophobic and they exhibited an excellent biocompatibility, and biodegradability due to the existence of PCL...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28628773/temperament-and-behavior-in-toddlers-born-preterm-with-related-clinical-problems
#4
Rafaela Guilherme Monte Cassiano, Claudia Maria Gaspardo, Ricardo Augusto de Deus Faciroli, Francisco Eulógio Martinez, Maria Beatriz Martins Linhares
OBJECTIVE: The aim of this study was to compare temperament and behavior profiles among groups of preterm toddlers differentiated by level of prematurity and the presence of bronchopulmonary dysplasia (BPD) or retinopathy of prematurity (ROP), controlling for neonatal clinical conditions and chronological age. METHOD: The sample comprised 100 preterm toddlers segregated according to level of prematurity (75 very preterm and 25 moderate/late preterm) and presence of BPD (n=36) and ROP (n=63)...
June 16, 2017: Early Human Development
https://www.readbyqxmd.com/read/28624314/anatomical-and-refractive-outcomes-in-patients-with-treated-retinopathy-of-prematurity
#5
M Lolas, A Tuma, M Zanolli, R Agurto, R Stevenson, D Ossandón
OBJECTIVE: To describe the anatomical and refractive outcomes after treatment with intravitreal bevacizumab or laser in a patient cohort with retinopathy of prematurity (ROP). METHODS: A multicentre, prospective, and observational study was performed on patients with ROP treated at Hospital Roberto del Río. Those patients with less than 6months of follow-up were excluded. Cases with posterior zone II, zone I ROP, and aggressive posterior ROP (AP-ROP) were treated with intravitreal bevacizumab...
June 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28613356/outpatient-wide-field-digital-imaging-of-infants-with-retinopathy-of-prematurity
#6
Robert W Arnold, Robin L Grendahl, R Kevin Winkle, Jack Jacob
Eight infants were closely monitored for retinopathy of prematurity (ROP) while in the neonatal intensive care unit (NICU); two required laser therapy. After discharge from the NICU, they had outpatient examination with dilated, scleral depressed ROP staging, and each had digital widefield retinal imaging (Optos, Dunfermline, United Kingdom) without lid speculum, or with lid speculum if not cooperative. Images were shared remotely using ROP-Check software (Glacier Medical Software, Anchorage, AK), from which ophthalmologists made clinical impressions...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28611651/usefulness-of-intravitreal-bevacizumab-for-retinopathy-of-prematurity-with-severely-dilated-tunica-vasculosa-lentis-and-poor-mydriasis
#7
Tomoaki Higashiyama, Sanae Muraki, Masahito Ohji
BACKGROUND: Laser therapy has been the gold standard treatment for retinopathy of prematurity (ROP), while intravitreal bevacizumab (IVB) is reported to be of significant benefit for zone I ROP. A problem with laser therapy is that it is difficult to administer in ROP patients with severely dilated tunica vasculosa lentis and poor mydriasis. However, although IVB treatment has been performed in such severe ROP cases, only 1 report has discussed its usefulness. CASE 1: A male infant was born with a birth weight of 382 g at 23 weeks' gestation...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28591403/preliminary-multiplex-microarray-igg-immunoassay-for-the-diagnosis-of-toxoplasmosis-and-rubella
#8
Priscila T Baschirotto, Marco A Krieger, Leonardo Foti
BACKGROUND: During pregnancy, toxoplasmosis and rubella can cause serious damage to the mother and the foetus through vertical transmission. Early diagnosis enables implementation of health measures aimed at preventing vertical transmission and minimising damage caused by these diseases. OBJECTIVE: Here, we report the development of a multiplex assay for simultaneous detection of IgG antibodies produced during toxoplasmosis and rubella infection. METHODS: This assay is based on xMap technology...
June 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28588680/early-clinical-characteristics-of-bacterial-endophthalmitis-in-retinopathy-of-prematurity-after-intravitreal-bevacizumab-injection-a-case-report
#9
Jianxun Wang, Daoman Xiang
Intravitreal bevacizumab injection (IVB) is emerging as a safe and effective therapy for retinopathy of prematurity (ROP); however, follow-up investigations after IVB have indicated that endophthalmitis, a rare and devastating complication, may develop. The present study reports a case of an infant with ROP who developed endophthalmitis after IVB infection. The infant was administered with an intravitreal injection of broad-spectrum antibiotics to treat the endophthalmitis. A favorable anatomic outcome was achieved after follow-up...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28587883/investigation-of-the-effect-of-hemoglobin-f-and-a-levels-on-development-of-retinopathy-of-prematurity
#10
Hidayet Erdöl, Dilek Hacioglu, Mehmet Kola, Adem Türk, Yakup Aslan
PURPOSE: To investigate the effect of hemoglobin F (HbF) and hemoglobin A (HbA) levels on development of retinopathy of prematurity (ROP) in premature infants. METHODS: In this prospective study, blood samples were collected from the side of the heel of 49 premature infants at postnatal months 0, 1, 2 and 3. HbF and HbA levels were measured in all samples and analyzed statistically. Furthermore, correlation analysis was performed regarding development of ROP, blood transfusion and HbF and HbA levels...
June 3, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28587880/colorado-retinopathy-of-prematurity-co-rop-screening-algorithm-a-validation-study-at-a-tertiary-care-center
#11
Jason M Huang, Xihui Lin, Yu-Guang He, Jennifer H Cao
PURPOSE: The Colorado retinopathy of prematurity (CO-ROP) model is a novel screening algorithm that recommends screening for ROP in infants meeting the following criteria: gestational age ≤30 weeks, birth weight of ≤1500 g, and a net weight gain of ≤650 g between birth and 4 weeks of age. This study was performed to evaluate the validity of the CO-ROP model in a tertiary referral county hospital. METHODS: Three hundred seventy-four consecutive newborns screened for ROP using national screening guidelines at Parkland Hospital (Dallas, TX) from April 1, 2009 to August 30, 2013 were retrospectively applied to the CO-ROP model...
June 3, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28576764/early-postnatal-hyperglycaemia-is-a-risk-factor-for-treatment-demanding-retinopathy-of-prematurity
#12
Carina Slidsborg, Louise Bering Jensen, Steen Christian Rasmussen, Hans Callø Fledelius, Gorm Greisen, Morten de la Cour
BACKGROUND: To investigate whether neonatal hyperglycaemia in the first postnatal week is associated with treatment-demanding retinopathy of prematurity (ROP). METHODS: This is a Danish national, retrospective, case-control study of premature infants (birth period 2003-2006). Three national registers were searched, and data were linked through a unique civil registration number. The study sample consisted of 106 cases each matched with two comparison infants. Matching criteria were gestational age (GA) at birth, ROP not registered and born at the same neonatal intensive care unit...
June 2, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28574986/an-ethnobotanical-survey-of-indigenous-medicinal-plants-in-hafizabad-district-punjab-pakistan
#13
Muhammad Umair, Muhammad Altaf, Arshad Mehmood Abbasi
Present paper offers considerable information on traditional uses of medicinal plants by the inhabitants of Hafizabad district, Punjab-Pakistan. This is the first quantitative ethnobotanical study from the area comprising popularity level of medicinal plant species intendedby using relative popularity level (RPL) and rank order priority (ROP) indices.Ethnobotanical data were collected by interviewing 166 local informants and 35 traditional health practioners (THPs) from different localities of Hafizabad district...
2017: PloS One
https://www.readbyqxmd.com/read/28573995/impact-of-expansion-of-telemedicine-screening-for-retinopathy-of-prematurity-in-india
#14
Anand Vinekar, Shwetha Mangalesh, Chaitra Jayadev, Clare Gilbert, Mangat Dogra, Bhujang Shetty
PURPOSE: The purpose of this study is to estimate the unknown burden of retinopathy of prematurity (ROP) blindness from nine states of India using demographic, incidence and treatment data from an ongoing statewide ROP program in Karnataka called the Karnataka Internet Assisted Diagnosis of ROP (KIDROP) and to calculate the fiscal quantum of preventable blindness in these states. MATERIALS AND METHODS: The KIDROP model is an ongoing tele-ROP service providing screening and treatment for ROP in Karnataka since 2008...
May 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28573924/the-lack-of-association-between-vascular-endothelial-growth-factor-and-retinopathy-of-prematurity-in-an-observational-study
#15
Yogavijayan Kandasamy, Leo Hartley, Donna Rudd, Roger Smith
PURPOSE: The objective of this study was to investigate the association between prematurity, vascular endothelial growth factor A (VEGF-A), VEGFR-1 (soluble fms-like tyrosine kinase-1 (sFLT-1)) and retinopathy of prematurity (ROP). METHODS: A cohort of 53 neonates (gestation <28 weeks) was recruited into this study and peripheral venous samples for VEGF and sFLT-1 measurement were obtained between gestational ages 32(0)-32(6) weeks. RESULTS: The mean birth weight for the preterm neonates was 850 (178) g and the median gestational age was 26...
June 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28573047/simultaneous-fluorescein-angiography-and-spectral-domain-optical-coherence-tomography-correlate-retinal-thickness-changes-to-vascular-abnormalities-in-an-in-vivo-mouse-model-of-retinopathy-of-prematurity
#16
Olachi J Mezu-Ndubuisi, Lauren K Taylor, Jamee A Schoephoerster
BACKGROUND: Retinopathy of prematurity (ROP) is a condition of abnormal retinal vascular development (RVD) in premature infants. Fluorescein angiography (FA) has depicted phases (early, mid, late, and mature) of RVD in oxygen-induced retinopathy (OIR) mice. We sought to establish the relationship between retinal structural and vascular changes using simultaneous FA and spectral domain optical coherence tomography (SD-OCT). METHOD: 63 mice were exposed to 77% oxygen at postnatal day 7 (P7) for 5 days, while 63 mice remained in room air (RA)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28548651/foetal-haemoglobin-blood-transfusion-and-retinopathy-of-prematurity-in-very-preterm-infants-a-pilot-prospective-cohort-study
#17
C J Stutchfield, A Jain, D Odd, C Williams, R Markham
PurposeTo identify if there is an association between foetal haemoglobin (HbF) concentration and retinopathy of prematurity (ROP) in very preterm infants.Patients and methodsProspective cohort study. Infants born <32 weeks' gestational age or <1501 g in two tertiary neonatal units between January 2012 and May 2013 (n=42) were enrolled. HbF and adult haemoglobin (HbA) concentrations were measured using high-pressure liquid chromatography from blood samples sent as part of routine neonatal care once routinely requested laboratory tests had been performed...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28545834/the-relationship-of-the-subtypes-of-preterm-birth-with-retinopathy-of-prematurity
#18
Anne M Lynch, Brandie D Wagner, Jennifer K Hodges, Tamara S Thevarajah, Emily A McCourt, Ashlee M Cerda, Naresh Mandava, Ronald S Gibbs, Alan G Palestine
BACKGROUND: Retinopathy of prematurity is an adverse outcome of preterm birth and is a leading cause of childhood blindness. The relationship between the subtypes of preterm birth with retinopathy of prematurity is understudied. OBJECTIVE: To investigate whether there is a difference in the incidence of type 1 or type 2 retinopathy of prematurity in infants with preterm birth resulting from spontaneous preterm labor, a medical indication of preterm birth, or preterm premature rupture of the membranes...
May 22, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28541957/the-cutting-edge-of-retinopathy-of-prematurity-care-expanding-the-boundaries-of-diagnosis-and-treatment
#19
Yoshihiro Yonekawa, Benjamin J Thomas, Aristomenis Thanos, Bozho Todorich, Kimberly A Drenser, Michael T Trese, Antonio Capone
PURPOSE: To discuss the latest advances and controversies in the diagnosis and care of infants with retinopathy of prematurity (ROP). METHODS: Literature review. RESULTS: Retinopathy of prematurity remains a major global issue. Industrialized nations now treat profoundly premature infants with posterior and aggressive disease, and middle-income nations are experiencing ROP epidemics. Remote digital imaging may address the decreasing ratio of ROP providers to premature infants, in addition to improving patient care...
May 24, 2017: Retina
https://www.readbyqxmd.com/read/28539261/g-protein-coupled-receptor-91-signaling-in-diabetic-retinopathy-and-hypoxic-retinal-diseases
#20
Jianyan Hu, Tingting Li, Xinhua Du, Qiang Wu, Yun-Zheng Le
G protein-coupled receptor 91 (GPR91) is a succinate-specific receptor and activation of GPR91 could initiate a complex signal transduction cascade and upregulate inflammatory and pro-angiogenic cytokines. In the retina, GPR91 is predominately expressed in ganglion cells, a major cellular entity involved in the pathogenesis of diabetic retinopathy (DR) and other hypoxic retinal diseases. During the development of DR and retinopathy of prematurity (ROP), chronic hypoxia causes an increase in the levels of local succinate...
May 21, 2017: Vision Research
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