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https://www.readbyqxmd.com/read/27908913/comfrey-herbal-remedy-causing-second-degree-heart-block-do-not-be-outfoxed-by-digitalis
#1
Mathew Kurian Vithayathil, Matthew Edwards
A previously well woman aged 63 years presents to the emergency department with vomiting, palpitations and 3 presyncopal episodes. She had no previous medical or cardiac history, with the patient stating that she tried a herbal remedy of boiled comfrey leaves for insomnia 18 hours before arrival to the department. Her ECG showed multiple abnormalities, including bradycardia, second-degree atrioventricular node block, Mobitz Type 2, a shortened QT interval, downsloping ST depression and presence of U waves...
December 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27908158/similarity-measurement-of-lung-masses-for-medical-image-retrieval-using-kernel-based-semisupervised-distance-metric
#2
Guohui Wei, He Ma, Wei Qian, Min Qiu
PURPOSE: To develop a new algorithm to measure the similarity between the query lung mass and reference lung mass data set for content-based medical image retrieval (CBMIR). METHODS: A lung mass data set including 746 mass regions of interest (ROIs) was assembled. Among them, 375 ROIs depicted malignant lesions and 371 depicted benign lesions. Each mass ROI is represented by a vector of 26 texture features. A kernel function was employed to map the original data in input space to a feature space...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27906601/association-between-pre-operative-cefazolin-dose-and-surgical-site-infection-in-obese-patients
#3
William J Peppard, David G Eberle, Nathan W Kugler, Danielle M Mabrey, John A Weigelt
BACKGROUND: A fixed dose of cefazolin results in serum concentrations that decrease as body mass increases. Current national guidelines suggest a pre-operative cefazolin dose of two grams may be insufficient for patients ≥120 kg; thus a three gram dose is recommended. These recommendations, however, are based on pharmacokinetic rather than outcome data. We evaluate the efficacy of pre-operative cefazolin two gram and three gram doses as measured by the rate of surgical site infection (SSI)...
December 1, 2016: Surgical Infections
https://www.readbyqxmd.com/read/27903999/burnout-syndrome-among-hemodialysis-and-peritoneal-dialysis-nurses
#4
Ayten Karakoc, Murvet Yilmaz, Nilufer Alcalar, Bennur Esen, Hasan Kayabasi, Dede Sit
INTRODUCTION: Burnout, a syndrome with 3 dimensions of emotional exhaustion, depersonalization, and reduction of personal accomplishment, is very common among hemodialysis nurses, while data are scarce regarding the prevalence of burnout syndrome (BS) among peritoneal dialysis (PD) nurses. This study aimed to assess and compare demographic and professional characteristics and burnout levels in hemodialysis and PD nurses, and to investigate factors that increase the level of burnout in dialysis nurses...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27903252/shifting-tides-in-the-emigration-patterns-of-canadian-physicians-to-the-united-states-a-cross-sectional-secondary-data-analysis
#5
Thomas R Freeman, Stephen Petterson, Sean Finnegan, Andrew Bazemore
BACKGROUND: The relative ease of movement of physicians across the Canada/US border has led to what is sometimes referred to as a 'brain drain' and previous analysis estimated that the equivalent of two graduating classes from Canadian medical schools were leaving to practice in the US each year. Both countries fill gaps in physician supply with international medical graduates (IMGs) so the movement of Canadian trained physicians to the US has international ramifications. Medical school enrolments have been increased on both sides of the border, yet there continues to be concerns about adequacy of physician human resources...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27898260/inpatient-palliative-care-for-neurological-disorders-lessons-from-a-large-retrospective-series
#6
Ying Liu, Danielle Kline, Shanae Aerts, Jeanie M Youngwerth, Jean S Kutner, Stefan Sillau, Benzi M Kluger
BACKGROUND: Patients with neurological disorders are the second most common patient population to receive inpatient palliative care services after cancer; however, there have been few reports describing the characteristics and needs of this population. OBJECTIVE: To understand which patients with neurological diagnoses utilized these services, reasons for consultation, and whether patterns of use changed over time. DESIGN: Retrospective case series...
November 29, 2016: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#7
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
November 25, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27890564/phytochemical-and-phytopharmacological-review-of-perilla-frutescens-l-labiatae-a-traditional-edible-medicinal-herb-in-china
#8
Hua Yu, Jian Feng Qiu, Li Juan Ma, Yuan Jia Hu, Peng Li, Jian Bo Wan
Perilla frutescens (L.) Britt., a worldwide distributed plant, is an important economic crop and with a long cultivation history in China as well as some other countries in Asia. Except for the edible applications, the plant of P. frutescens is also traditionally used as a medicinal herb in China for thousands years. The leaves, seeds and stems of P. frutescens are recommended by the Chinese Pharmacopeia as three medicinal materials for various therapeutic applications. In the past decades, amount investigations have been done about different aspects for P...
November 24, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27890030/longitudinal-emergency-medical-technician-attributes-and-demographic-study-leads-design-and-methodology
#9
Roger Levine
OBJECTIVES: The objective of this study is to describe the Longitudinal Emergency Medical Technician (EMT) Attributes and Demographic Study (LEADS) design, instrument development, pilot testing, sampling procedures, and data collection methodology. Response rates are provided, along with results of follow-up surveys of non-responders (NRs) and a special survey of Emergency Medical Services (EMS) professionals who were not nationally certified. METHODS: Annual surveys from 1999 to 2008 were mailed out to a random, stratified sample of nationally registered EMT-Basics and Paramedics...
November 28, 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27886882/pharmacologic-management-of-acute-spinal-cord-injury
#10
REVIEW
Michael Karsy, Gregory Hawryluk
Spinal cord injury is a serious global public health problem that often leaves patients with devastating permanent disabilities. Although advances in supportive care have improved outcome in recent decades, there remains great need for a safe and efficacious medical treatment that improves neurologic outcome. This article reviews pharmacologic treatments evaluated or in the process of development in humans. Cellular transplantation strategies are briefly reviewed especially where they have been evaluated with pharmacologic treatments...
January 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/27884918/patients-beliefs-on-the-impediments-to-good-diabetes-control-a-mixed-methods-study-of-patients-in-general-practice
#11
Amanda Jane Elliott, Fiona Harris, Sandra G Laird
BACKGROUND: Most people with diabetes are not attaining desirable levels of HbA1c (glycated haemoglobin), or of blood pressure and cholesterol, leaving them at risk of developing complications. AIM: To identify ways of improving diabetes control by gaining insight into patients' attitudes/beliefs. DESIGN AND SETTING: Questionnaires were offered to patients attending for a diabetes review in the 24 GP practices of North East Hampshire and Farnham Clinical Commissioning Group...
December 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/27884215/public-perception-of-emergency-medical-services-in-the-united-states
#12
Remle P Crowe, Roger Levine, Severo Rodriguez, Ashley D Larrimore, Ronald G Pirrallo
OBJECTIVE: The objective of this study was to assess the public's experience, expectations, and perceptions related to Emergency Medical Services (EMS). METHODS: A population-based telephone interview of adults in the United States was conducted. The survey instrument consisted of 112 items. Demographic variables including age, race, political beliefs, and household income were collected. Data collection was performed by trained interviewers from Kent State University's (Kent, Ohio USA)Social Research Laboratory...
November 25, 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27884042/valproate-for-schizophrenia
#13
REVIEW
Yijun Wang, Jun Xia, Bartosz Helfer, Chunbo Li, Stefan Leucht
BACKGROUND: Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used, and valproate is one of these. OBJECTIVES: To examine whether:1. valproate alone is an effective treatment for schizophrenia and schizoaffective psychoses; and2. valproate augmentation of antipsychotic medication is an effective treatment for the same illnesses. SEARCH METHODS: We searched the Cochrane Schizophrenia Group's Study-Based Register of Trials (July 2002; February 2007; July 2012; March 04, 2016)...
November 24, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27877047/antiallergic-effect-of-the-atomized-extract-of-rhizome-of-curcuma-longa-flowers-of-cordia-lutea-and-leaves-of-annona-muricata
#14
Jorge Arroyo-Acevedo, Cesar Franco-Quino, Eliberto Ruiz-Ramirez, Roberto Chávez-Asmat, Andrea Anampa-Guzmán, Ernesto Raéz-González, José Cabanillas-Coral
INTRODUCTION: Allergies are a problem that greatly affects the population, and hence the use of antiallergic medications is fairly widespread. However, these drugs have many adverse effects. The use of medicinal plants could be an option, but they need to be evaluated. OBJECTIVE: This study was designed to evaluate the antiallergic effect of the atomized extract of rhizome of Curcuma longa, flowers of Cordia lutea, and leaves of Annona muricata. MATERIALS AND METHODS: Twenty-four New Zealand white albino rabbits were randomized into 2 groups...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27871822/geroscience-addressing-the-mismatch-between-its-exciting-research-opportunities-its-economic-imperative-and-its-current-funding-crisis
#15
REVIEW
George M Martin
There is at present a huge disconnect between levels of funding for basic research on fundamental mechanisms of biological aging and, given demographic projections, the anticipated enormous social and economic impacts of a litany of chronic diseases for which aging is by far the major risk factor: One valuable approach, recently instigated by Felipe Sierra & colleagues at the US National Institute on Aging, is the development of a Geroscience Interest Group among virtually all of the NIH institutes. A complementary approach would be to seek major escalations of private funding...
November 18, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27871000/comparison-of-atlas-based-techniques-for-whole-body-bone-segmentation
#16
Hossein Arabi, Habib Zaidi
We evaluate the accuracy of whole-body bone extraction from whole-body MR images using a number of atlas-based segmentation methods. The motivation behind this work is to find the most promising approach for the purpose of MRI-guided derivation of PET attenuation maps in whole-body PET/MRI. To this end, a variety of atlas-based segmentation strategies commonly used in medical image segmentation and pseudo-CT generation were implemented and evaluated in terms of whole-body bone segmentation accuracy. Bone segmentation was performed on 23 whole-body CT/MR image pairs via leave-one-out cross validation procedure...
November 12, 2016: Medical Image Analysis
https://www.readbyqxmd.com/read/27870104/clinical-experience-with-daptomycin-in-pediatrics
#17
Katie C Namtu, Julianna C Crain, Allison F Messina, Juan A Dumois, David M Berman
INTRODUCTION: The management of Gram-positive infections has been complicated in recent years by the emergence of antimicrobial resistance, leaving fewer options for therapy. Daptomycin is a lipopeptide antibiotic used for the systemic treatment of Gram-positive infections and has a distinct mechanism of action, favorable side effect profile, and requires once daily dosing. Unfortunately, there is a paucity of safety, efficacy, and pharmacokinetic data in neonatal and pediatric patients...
November 21, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27864987/-mental-health-day-sickness-absence-amongst-nurses-and-midwives-workplace-workforce-psychosocial-and-health-characteristics
#18
Scott Lamont, Scott Brunero, Lin Perry, Christine Duffield, David Sibbritt, Robyn Gallagher, Rachel Nicholls
AIM: To examine the workforce, workplace, psychosocial and health characteristics of nurses and midwives in relation to their reported use of sickness absence described as 'mental health days'. BACKGROUND: The occupational stress associated with the nursing profession is increasingly recognised and nurse/midwifery absenteeism is a significant global problem. Taking a 'mental health day' as sickness absence is a common phenomenon in Australian healthcare. No previous studies have empirically explored the characteristics of nurses and midwives using such sickness absence...
November 16, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27862117/irritable-bowel-syndrome-and-active-inflammatory-bowel-disease-diagnosed-by-faecal-gas-analysis
#19
R B M Aggio, P White, H Jayasena, B de Lacy Costello, N M Ratcliffe, C S J Probert
BACKGROUND: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, there are no tests to positively diagnose irritable bowel syndrome and invasive tests are still used to rule out other pathologies. AIM: To investigate a platform technology for diagnosing inflammatory bowel disease and irritable bowel syndrome based on faecal gas...
January 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27858472/approaches-to-biofilm-associated-infections-the-need-for-standardized-and-relevant-biofilm-methods-for-clinical-applications
#20
Matthew Malone, Darla M Goeres, Iain Gosbell, Karen Vickery, Slade Jensen, Paul Stoodley
The concept of biofilms in human health and disease is now widely accepted as cause of chronic infection. Typically, biofilms show remarkable tolerance to many forms of treatments and the host immune response. This has led to vast increase in research to identify new (and sometimes old) anti-biofilm strategies that demonstrate effectiveness against these tolerant phenotypes. Areas covered: Unfortunately, a standardized methodological approach of biofilm models has not been adopted leading to a large disparity between testing conditions...
November 18, 2016: Expert Review of Anti-infective Therapy
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