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Pituitary apoplexy

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https://www.readbyqxmd.com/read/29928451/an-exceptional-presentation-of-pituicytoma-apoplexy-a-case-report
#1
Giulia Cossu, Julien Dimitriou, Jean-Philippe Brouland, Roy Thomas Daniel, Mahmoud Messerer
Pituicytomas are a rare form of indolent neoplasms, which typically present with visual disturbance and hypopituitarism. Complete resection by a trans-sphenoidal approach is the optimal treatment. Only 80 cases have been described thus far in the current literature and the present case is the first to describe the development of pituitary apoplexy in the context of a pituicytoma. A 77-year-old man presented with fatigue and clinical signs of hypogonadism and a sellar lesion was diagnosed at cerebral magnetic resonance imaging (MRI)...
July 2018: Oncology Letters
https://www.readbyqxmd.com/read/29860715/myasthenia-gravis-imitating-pituitary-apoplexy-in-macroprolactinoma
#2
REVIEW
Matteo Zoli, Federica Guaraldi, Marco Faustini, Diego Mazzatenta
Myasthenia gravis (MG) is an autoimmune disease affecting neuromuscular transmission that manifests with muscle weakness and typically involves the eye muscles, often producing diplopia and ptosis. Recent studies suggest that hyperprolactinaemia may have a role in the development of MG, although its association with prolactinoma is extremely rare. We report the unusual case of a 71-year-old male affected with macroprolactinoma, who presented at our Center 2 weeks after starting cabergoline treatment because of acute onset of headache, diplopia, and ptosis...
June 2, 2018: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29845000/pituitary-abscess-a-rare-clinical-entity-in-the-presence-of-acute-rhinosinusitis-a-case-report
#3
Vincent John Anagnos, Ricardo A Hanel, Iman Naseri
A pituitary abscess is an often-overlooked diagnosis in the clinical presentation of a sellar mass. Due to its rare incidence and nonspecific presentation, diagnosis and treatment is often delayed. The authors describe a 56-year-old male patient presenting with acute onset of severe headache, visual field deficit, and radiologic findings of an expansile sellar lesion. The presenting symptoms were unremarkable for the diagnosis of meningitis, cavernous sinus thrombosis, and septicemia. Recent medical history included symptoms of rhinosinusitis on the days preceding his acute presentation...
April 2018: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/29742711/pituitary-apoplexy-following-lumbar-fusion-surgery-in-prone-position-a-case-report
#4
Chunghee Joo, Geol Ha, Yeon Jang
RATIONALE: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. PA following spinal surgery is a very rare complication and may be difficult to diagnose. However, early diagnosis of PA is essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications. PATIENT CONCERNS: A 73-year-old man had a posterior lumbar fusion surgery over a period of 8 hours on prone position...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29717570/extensive-pituitary-apoplexy-after-chemotherapy-in-a-patient-with-metastatic-breast-cancer
#5
Je Hun Jang, Young San Ko, Eun Kyeong Hong, Ho Shin Gwak
Surgery, anticoagulation therapy, pregnancy, and hormone treatments, such as bromocriptine, are well-characterized precipitating factors for pituitary apoplexy. However, whether cytotoxic chemotherapy for systemic cancer could cause pituitary apoplexy has not been investigated. Here, we present a case of a 41-year-old woman who developed a severe headache with decreased visual acuity after intravenous cytotoxic chemotherapy to treat metastatic breast cancer. Preoperative neuroimaging revealed pituitary adenoma with necrosis...
April 2018: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29709755/the-outcomes-of-pituitary-apoplexy-with-conservative-treatment-experiences-at-a-single-institution
#6
Youngbeom Seo, Yong Hwy Kim, Yun-Sik Dho, Jung Hee Kim, Jin Wook Kim, Chul-Kee Park, Dong Gyu Kim
OBJECTIVE: Pituitary apoplexy is an unpredictable complication caused by hemorrhage or infarction in a pituitary adenoma. We retrospectively analyzed the radiologic and clinical outcomes of patients with conservatively managed pituitary apoplexy. METHODS: A total of 32 patients who had undergone conservative treatment with high-dose corticosteroid replacement were enrolled in this study. This cohort study consisted of 20 male and 12 female patients. The median patient age was 60 years...
April 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29675363/clinical-and-imaging-features-of-pituitary-apoplexy-and-role-of-imaging-in-differentiation-of-clinical-mimics
#7
REVIEW
Pradeep Goyal, Michael Utz, Nishant Gupta, Yogesh Kumar, Manisha Mangla, Sonali Gupta, Rajiv Mangla
To discuss the clinical syndrome, review common imaging findings of pituitary apoplexy (PA) and role of imaging in therapy and follow-up. Also, to review other acute clinical scenarios with similar clinical and/or imaging findings as PA. PA is a severe and potentially life-threatening medical emergency, characterized by constellation of symptoms/signs that occur as a result of acute hemorrhage and/or infarction in pituitary gland. Patients present with acute and sudden onset of symptoms/signs, most commonly with severe headache, vision deficits/ophthalmoplegia, altered mental status, and possible pan hypopituitarism...
March 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29615979/landscape-of-molecular-events-in-pituitary-apoplexy
#8
REVIEW
Prakamya Gupta, Pinaki Dutta
Apoplectic pituitary adenomas cause significant morbidity and even mortality. The pituitary apoplexy denotes a pituitary adenoma presenting with hemorrhage and/or infarction, implementation in remedial effects of various of drugs in pituitary apoplexy is a promising pharmacogenomic field in the near future adenoma treatment. Indisputably, this is an important horizon for complicated pituitary adenomas. In a pituitary adenoma, the interplay between genetic, cytokine, and growth factors promotes the pathogenic transformation into an apoplectic formation...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29610617/rathke-s-cleft-cyst-or-pituitary-apoplexy-a-case-report-and-literature-review
#9
Jeton Shatri, Ilir Ahmetgjekaj
BACKGROUND: During the examination of the sellar region by magnetic resonance imaging, hyperintensity in T1 weighted is a common finding. This signal intensity has different sources, and its significance depends on the clinical context. Pathologic variations in T1 signal hyperintensity may be related to clotting of blood (pituitary apoplexy) or the presence of a high concentration of protein (Rathke cleft cyst). The purpose of this study is to describe the significance of intracystic nodule, a diagnostic characteristic found in Rathke's cleft cyst, on MRI...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29593947/angioplasty-is-an-effective-treatment-for-vasospasm-following-pituitary-apoplexy-and-tumor-resection
#10
Diana G Douleh, Peter J Morone, Bret Mobley, Matthew R Fusco, Lola B Chambless
Pituitary apoplexy is a clinical syndrome characterized by acute headache, visual changes, and decreased consciousness occurring in association with hemorrhage or infarct of an existing pituitary adenoma. Surgical management involves tumor resection and decompression of surrounding structures including the optic apparatus. Vasospasm is a rare but potentially devastating complication of pituitary apoplexy. We present a case of pituitary apoplexy in a 28-year-old male treated with emergent endoscopic transsphenoidal resection...
January 26, 2018: Curēus
https://www.readbyqxmd.com/read/29588904/endoscopic-endonasal-approach-for-complex-macroadenoma-with-suprasellar-and-retrochiasmatic-extension
#11
Edinson Najera, Carl H Snyderman, Juan C Fernandez-Miranda
In this video, we describe the technical nuances of an endoscopic endonasal approach (EEA) for a complex macroadenoma with suprasellar and retrochiasmatic extension. The patient is a 51-year-old male with several years' history of progressive visual loss. Neuro-ophthalmology assessment revealed a profound visual loss with homonymous hemianopsia and left optic nerve atrophy. His pituitary hormonal profile was normal. The options for surgical approach included transcranial, endoscopic endonasal, or a combination of both...
April 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29545227/clinical-outcomes-after-endoscopic-endonasal-resection-of-giant-pituitary-adenomas
#12
Khaled Elshazly, Varun R Kshettry, Christopher J Farrell, Gurston Nyquist, Marc Rosen, James J Evans
BACKGROUND: Giant pituitary adenomas represent a surgical challenge. We present the results of the endoscopic endonasal approach (EEA) for giant pituitary adenomas. METHODS: We retrospectively reviewed the medical records of 55 patients with giant pituitary adenomas (>4 cm in maximum diameter) who underwent surgery with an EEA between 2008 and 2016. Factors affecting the extent of resection were evaluated. RESULTS: The mean patient age was 55...
June 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29534208/pituitary-apoplexy-with-a-binasal-visual-field-defect
#13
Teiko Kawahigashi, Sho Nishiguchi
No abstract text is available yet for this article.
March 9, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29492132/pituitary-apoplexy-during-treatment-of-prolactinoma-with-cabergoline
#14
Hesam Ghadirian, Mohamad Shirani, Shahab Ghazi-Mirsaeed, Saleh Mohebi, Maysam Alimohamadi
Pituitary apoplexy is a rare clinical presentation caused by infarction of the pituitary gland or adenoma with or without hemorrhage. Although pituitary apoplexy is usually spontaneous, one of the predisposing factors is treatment with dopamine agonists, especially bromocriptine. The occurrence of apoplexy during cabergoline therapy is reported much less frequently. In this article, we report a 34-year-old man with macroprolactinomas who developed sudden visual deterioration due to pituitary apoplexy 1 year after initiation of cabergoline therapy...
January 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29456390/evaluation-of-clinical-and-magnetic-resonance-imaging-profile-of-pituitary-macroadenoma-a-prospective-study
#15
Kamini Gupta, Shivam Sahni, Kavita Saggar, Gaurav Vashisht
Background: Pituitary macroadenoma is a common tumor of middle-aged people. Magnetic resonance imaging (MRI) is the investigation of choice for its evaluation. Various parameters regarding the extent, consistency, and contrast uptake can be studied and a noninvasive diagnosis is possible. Aims and Objectives: To study the MRI features and extent of pituitary macroadenomas. Materials and Methods: We studied clinical and MRI features of 33 patients of all age groups and both sexes with pituitary macroadenomas who presented to Dayanand Medical College and Hospital, Ludhiana from January 2014 to June 2015...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29398620/corrigendum-to-in-reply-to-the-letter-to-the-editor-regarding-endoscopic-endonasal-surgery-for-pituitary-apoplexy-evidence-on-a-75-case-series-from-a-tertiary-care-center-world-neurosurgery-109-2018-502
#16
Matteo Zoli, Laura Milanese, Marco Faustini-Fustini, Federica Guaraldi, Sofia Asioli, Corrado Zenesini, Alberto Righi, Giorgio Frank, Maria Pia Foschini, Carmelo Sturiale, Ernesto Pasquini, Diego Mazzatenta
No abstract text is available yet for this article.
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29383476/apoplexy-in-nonfunctioning-pituitary-adenomas
#17
REVIEW
Luiz Eduardo Wildemberg, Andrea Glezer, Marcello D Bronstein, Mônica R Gadelha
Pituitary apoplexy is an uncommon event, occurring due to the infarction and/or haemorrhage usually of a previously unknown pituitary adenoma. It can occur in all adenoma subtypes but is more common in nonfunctioning pituitary adenomas. The physiopathology is not completely clear, and precipitating factors, such as major surgeries, anticoagulant use or pituitary dynamic tests, can be found in up to 40% of patients. The clinical presentation is characterized by a rapid onset with a headache as the main symptom, but visual disturbances can also be present as well as meningism and intracranial hypertension...
April 2018: Pituitary
https://www.readbyqxmd.com/read/29368293/epidemiology-clinical-presentation-and-diagnosis-of-non-functioning-pituitary-adenomas
#18
REVIEW
Georgia Ntali, John A Wass
PURPOSE: Non-functioning pituitary adenomas (NFPAs) are benign pituitary neoplasms that do not cause a hormonal hypersecretory syndrome. An improved understanding of their epidemiology, clinical presentation and diagnosis is needed. METHOD: A literature review was performed using Pubmed to identify research reports and clinical case series on NFPAs. RESULTS: They account for 14-54% of pituitary adenomas and have a prevalence of 7-41.3/100,000 population...
April 2018: Pituitary
https://www.readbyqxmd.com/read/29344069/pituitary-ring-sign-plus-sphenoid-sinus-mucosal-thickening-neuroimaging-signs-of-pituitary-apoplexy
#19
REVIEW
Michael S Vaphiades
Two magnetic resonance imaging (MRI) signs of pituitary apoplexy are the "pituitary ring sign" and "sphenoid sinus mucosal thickening". The occurrence of both these MRI signs together in patients with ischaemic pituitary apoplexy was investigated. A literature review searching the terms "pituitary ring sign" and "sphenoid sinus mucosal thickening" in the context of pituitary apoplexy from 1990 until present was performed. To be included in the study, each case had to have ischaemic pituitary apoplexy defined as acute expansion of a pituitary adenoma or, less commonly, in a non-adenomatous gland, from infarction without haemorrhage or very little haemorrhage and a T1-weighted MRI of the brain with contrast that displayed both "sphenoid sinus mucosal thickening" and a "pituitary ring sign" either on an actual study (the author's cases) or in a figure in an article from the literature that could be reviewed and clearly illustrate these two signs...
December 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29288106/pituitary-apoplexy-should-endoscopic-surgery-be-the-gold-standard
#20
Joaquim Cruz Teixeira, José Lavrador, Diogo Simão, José Miguéns
BACKGROUND: Pituitary apoplexy is an uncommon, potentially fatal condition due to spontaneous ischemia or hemorrhage in a pituitary adenoma. The treatment of this disorder has long been a matter of debate. METHODS: Retrospective cohort study including all patients admitted with pituitary apoplexy in our department between 2005 and 2015 was undertaken. Clinical symptoms and signs on admission, treatment (conservative vs. surgical), neurologic deficit on discharge and at 6 months' follow-up, and endocrinologic evaluation at 6 months' follow-up were analyzed...
March 2018: World Neurosurgery
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