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Pituitary apoplexy

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https://www.readbyqxmd.com/read/29227295/an-unusual-presentation-of-pituitary-gland-apoplexy-with-noninfectious-meningitis
#1
Margaret LaPorte, Jenna Pollock, Michael Ward, James Fulcher
Pituitary adenomas make up 10% of intracranial tumors, but because of their location, they may go undetected for long periods. In this article, we report the case of a 68-year-old white man found deceased in his residence, who died of acute pituitary tumor apoplexy. He was known to have severe symptoms including acute headache, vision loss, and altered behavior. When found, his home was in extreme disarray, mimicking a possible assault. At autopsy, the decedent had multiple superficial abrasions about the upper and lower extremities, as well as a 2...
December 7, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29222208/hypersomatotropism-induced-secondary-polycythaemia-leading-to-spontaneous-pituitary-apoplexy-resulting-in-cure-of-acromegaly-and-remission-of-polycythaemia-the-virtuous-circle
#2
Shinjan Patra, Sugata Narayan Biswas, Joydip Datta, Partha Pratim Chakraborty
A young man with subtle clinical features suggestive of hypersomatotropism presented with acute-onset severe headache. Relevant investigations confirmed polycythaemia and growth hormone (GH)-secreting pituitary macroadenoma with apoplexy. Secondary polycythaemia and myeloproliferative disorders were ruled out. At follow-up after 3 months, resolution of polycythaemia and acromegaly was observed, evident on normal haemoglobin levels, a normocellular marrow, and normal insulin-like growth factor-1 (IGF-1) with glucose-suppressed GH levels...
December 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29208862/impact-of-magnetic-resonance-imaging-in-the-diagnosis-of-pituitary-adenoma
#3
M I Hossain, M G Hafiz, S Choudhury, G N Islam, A Islam, M M Ahsan, M M Hossain
Pituitary adenoma is the third most common primary intracranial neoplasm involving the adult population with clinical features due to excess or deficient hormone secretion or due to its mass effect. Debate about the diagnostic accuracy, sensitivity and specificity of MRI imaging in detecting pituitary adenoma has been continuing. The study was aimed to evaluate the accuracy, sensitivity and specificity of MR imaging in detecting pituitary adenoma. This cross sectional study was conducted in the Department of Radiology and imaging, Bangabandhu Sheikh Mujib medical University (BSMMU) from July 2013 to August 2015...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29191540/postoperative-neurological-outcome-in-patients-with-pituitary-apoplexy-after-transsphenoidal-surgery
#4
Young-Hoon Kim, Young Hyun Cho, Seok Ho Hong, Jeong Hoon Kim, Min-Seon Kim, Shin Kwang Khang, Eun Jung Lee, Kyuha Chong, Chang Jin Kim
No abstract text is available yet for this article.
November 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29191280/rare-uncommon-and-unusual-complications-after-pancreaticoduodenal-resection
#5
REVIEW
Thinzar M Lwin, Natasha Leigh, Mazen E Iskandar, Justin G Steele, Michael G Wayne, Avram M Cooperman
Complications after pancreaticoduodenal resection occur in at least 30% of patients. Most are a direct result of an intraoperative event, dissection, or anastomoses which account for the most serious morbidities, sepsis, pseudoaneurysms, and hemorrhage. Rarely, complications are due to the systemic impact of the procedure even if the procedure itself was unremarkable. Rare systemic complications after PDR (Transfusion transmitted Babesiosis, pituitary apoplexy, and TRALI) and a number of uncommon and unusual other complications are discussed...
February 2018: Surgical Clinics of North America
https://www.readbyqxmd.com/read/29182204/-long-qt-syndrome-and-polymorphic-ventricular-tachycardia-due-to-hypopituitarism-report-of-one-case
#6
José Miguel García-Castro, Antonia García-Martín, Emilio Guirao-Arrabal, Pedro Luis Carrillo-Alascio
Symptoms of hypopituitarism are usually chronic and nonspecific, but rarely the disease can have acute and life threatening manifestations. We report a 53 years old female with a pituitary adenoma that was admitted to our hospital because of syncope. The electrocardiogram showed sinus bradycardia with a prolonged QT interval. Frequent runs of non-sustained polymorphic ventricular tachycardia were noted on telemetry. The patient had a history of severe acute headaches in the previous days and laboratory tests revealed severe secondary hypothyroidism, adrenal insufficiency and a decrease in pituitary hormones...
July 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29167187/ischaemic-pituitary-tumour-apoplexy-and-concurrent-meningitis-a-diagnostic-dilemma
#7
Haris Hakeem, Shayan Sirat Maheen Anwar, Sarwar Jamil Siddiqui
Pituitary tumour apoplexy is a rare but potentially life threatening clinical syndrome that mostly results from haemorrhage in the pre-existent tumour. Pure ischaemic subtype of apoplexy is even rarer. The presentation can be hard to differentiate clinically from bacterial meningitis. Moreover, the presence of one does not necessarily exclude the other and early diagnosis of both conditions is imperative for timely management. We report a case of ischaemic pituitary tumour apoplexy that may have precipitated in the setting of bacterial meningitis...
November 21, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29055223/pituitary-apoplexy-a-single-center-retrospective-study-from-the-neurosurgical-perspective-and-review-of-the-literature
#8
Agnieszka Grzywotz, Bernadette Kleist, Lars C Möller, Volkmar H Hans, Sophia Göricke, Ulrich Sure, Oliver Müller, Ilonka Kreitschmann-Andermahr
OBJECTIVE: Thunderclap headache and visual disturbances are typical clinical features of pituitary apoplexy (PA). Because of the acute symptomatology, many patients are referred to a neurosurgical department without prior endocrinological assessment. It is the aim of the present study to analyze initial presenting symptoms, outcome and associated endocrine disturbances in a cohort of patients with pituitary apoplexy primarily seen by neurosurgeons. PATIENTS AND METHODS: Retrospective single-center study in a neurosurgical department...
December 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28980712/indomethacin-responsive-paroxysmal-hemicrania-in-an-elderly-man-an-unusual-presentation-of-pituitary-apoplexy
#9
Lou Grangeon, Lucas Moscatelli, Adrien Zanin, Audrey Rouille, David Maltete, Evelyne Guegan-Massardier
No abstract text is available yet for this article.
October 5, 2017: Headache
https://www.readbyqxmd.com/read/28979174/delayed-onset-of-isolated-unilateral-oculomotor-nerve-palsy-caused-by-post-traumatic-pituitary-apoplexy-a-case-report
#10
Tomoki Ishigaki, Yotaro Kitano, Hirofumi Nishikawa, Genshin Mouri, Shigetoshi Shimizu, Fumitaka Miya, Hidenori Suzuki
Post-traumatic pituitary apoplexy is uncommon, most of which present with a sudden onset of severe headache and visual impairments associated with a dumbbell-shaped pituitary tumor. We experienced an unusual case of post-traumatic pituitary apoplexy with atypical clinical features. A 66-year-old man presented with mild cerebral contusion and an incidentally diagnosed intrasellar tumor after a fall accident with no loss of consciousness. The patients denied any symptoms before the accident. After 4 days, the left oculomotor nerve palsy developed and deteriorated associated with no severe headache...
2017: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/28946177/surgical-intervention-for-pituitary-apoplexy-an-analysis-of-functional-outcomes
#11
Martin J Rutkowski, Sandeep Kunwar, Lewis Blevins, Manish K Aghi
OBJECTIVE Pituitary apoplexy is a clinical syndrome consisting of neurological and endocrine abnormalities secondary to hemorrhage or ischemia of an underlying pituitary adenoma. The authors investigated whether there was a significant difference in neurological, endocrine, and nonneuroendocrine outcomes for patients with pituitary apoplexy, based on the time between symptom onset and surgical intervention. METHODS The authors retrospectively analyzed the medical records of 32 patients who had presented to their institution with acute pituitary apoplexy and subsequently undergone endonasal transsphenoidal resection in the period from 2003 to 2014...
September 15, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28936095/repeated-headache-as-presentation-of-pituitary-apoplexy-in-the-adolescent-population-unusual-entity-with-review-of-literature
#12
Guru Dutta Satyarthee, B S Sharma
No abstract text is available yet for this article.
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28867316/endoscopic-endonasal-surgery-for-treatment-of-pituitary-apoplexy-16-years-of-experience-in-a-specialized-pituitary-center-endoscopic-surgery-for-pituitary-apoplexy
#13
Jackson A Gondim, Lucas Alverne F de Albuquerque, Joao Paulo Almeida, Tania Bulcao, Erica Gomes, Michele Schops, Raquel Vasconcelos, Flora da Paz, Sergio Botelho Guimarães
OBJECTIVE: Symptomatic pituitary apoplexy is a rare but life-threatening condition caused by sudden hemorrhage or infarction of a pituitary adenoma. In the current study, we aim to evaluate the clinical presentation, management and clinical outcomes in a cohort of patients who were treated for this condition in our center in the last 16 years. METHODS: We performed a retrospective analysis of all patients who underwent endoscopic endonasal surgery for treatment of symptomatic pituitary apoplexy between 2001 and 2016 in our center...
August 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28853001/sphenoid-sinus-microbiota-in-pituitary-apoplexy-a-preliminary-study
#14
Gavin J Humphreys, Mueez Waqar, Andrew J McBain, Kanna K Gnanalingham
PURPOSE: There is a high incidence of abnormal sphenoid sinus changes in patients with pituitary apoplexy (PA). Their pathophysiology is currently unexplored and may reflect an inflammatory or infective process. In this preliminary study, we characterised the microbiota of sphenoid sinus mucosa in patients with PA and compared findings to a control group of surgically treated non-functioning pituitary adenomas (NFPAs). METHODS: In this prospective observational study of patients undergoing trans-sphenoidal surgery for PA or NFPA, sphenoid sinus mucosal specimens were microbiologically profiled through PCR-cloning of the 16S rRNA gene...
December 2017: Pituitary
https://www.readbyqxmd.com/read/28835258/acute-hypopituitarism-associated-with-periorbital-swelling-and-cardiac-dysfunction-in-a-patient-with-pituitary-tumor-apoplexy-a-case-report
#15
Nobumasa Ohara, Yuichiro Yoneoka, Yasuhiro Seki, Katsuhiko Akiyama, Masataka Arita, Kazumasa Ohashi, Kazuo Suzuki, Toshinori Takada
BACKGROUND: Pituitary tumor apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction in a preexisting pituitary adenoma. It typically manifests as an acute episode of headache, visual disturbance, mental status changes, cranial nerve palsy, and endocrine pituitary dysfunction. However, not all patients present with classical symptoms, so it is pertinent to appreciate the clinical spectrum of pituitary tumor apoplexy presentation. We report an unusual case of a patient with pituitary tumor apoplexy who presented with periorbital edema associated with hypopituitarism...
August 24, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28831662/pituitary-apoplexy-and-rivaroxaban
#16
S Ly, A Naman, B Chaufour-Higel, M Patey, C Arndt, B Delemer, C F Litre
Pituitary apoplexy (PA), defined by the occurrence of a massive hemorrhagic necrotic rearrangement within a pituitary adenoma, is rare. Its occurrence can be associated with certain risk factors, including anticoagulation. We report the first case of PA with rivaroxaban which is one of the new oral anticoagulants: a 73 year-old patient presenting with severe headache and visual field deterioration. Surgery was performed. Radiotherapy treatment was decided three months after surgery because of tumor residue.
December 2017: Pituitary
https://www.readbyqxmd.com/read/28826864/surgical-outcomes-of-cavernous-sinus-syndrome-in-pituitary-adenomas
#17
Weilun Fu, Lian Duan, Sumin Geng
OBJECTIVE: The type of pituitary adenoma with a manifestation that includes cavernous sinus syndrome is rare. Based on the clinical data of 70 patients, this study investigated the pathogenesis, imaging characteristics, and prognostic factors of pituitary adenoma with cavernous sinus syndrome. METHODS: We conducted a retrospective analysis of the characteristics of patients with pituitary adenoma with cavernous sinus syndrome who received surgical treatment. The patients were classified into different prognosis groups according to the time required for them to recover from the cavernous sinus syndrome...
November 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28814709/spindle-cell-oncocytoma-of-the-anterior-pituitary-presenting-with-an-acute-clinical-course-due-to-intraventricular-hemorrhage-a-case-report-and-review-of-literature
#18
Mostafa Osman, Andrew Wild
BACKGROUND Spindle cell oncocytoma (SCO) is a rare nonfunctioning neoplasm of the adenohypophysis, and was first described in 2002. SCO has been categorized as a separate entity by the 2007 World Health Organization (WHO) and is classified as a Grade 1 tumor of the central nervous system (CNS). Review of the literature has shown that 33 cases of SCO have been reported to date, and most of them presented with a mass effect or with panhypopituitarism. However, all reported cases have described the tendency of SCO to be hypervascular on imaging and histology...
August 17, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28721598/a-retrospective-review-of-34-cases-of-pediatric-pituitary-adenoma
#19
Nannan Zhang, Peizhi Zhou, Yu Meng, Feng Ye, Shu Jiang
PURPOSE: The purpose of this paper is to study invasiveness, tumor features and clinical symptoms of pediatric pituitary adenoma, and to discuss some inconclusive results in prior studies. METHODS: We retrospectively reviewed 34 cases of children (<20 year-old) who were pathologically diagnosed with pituitary adenoma and surgically treated from 2010 to 2017. Data of general information, clinical symptoms, invasive behaviors, surgery approaches, and tumor features were collected and analyzed...
November 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28710301/pituitary-apoplexy-a-rare-complication-of-leuprolide-therapy-in-prostate-cancer-treatment
#20
Georges Tanios, Nicolas Andrews Mungo, Aaysha Kapila, Kailash Bajaj
Gonadotropin-releasing hormone agonists, used widely in the treatment of metastatic prostate cancer and hormone receptor-positive breast cancer, are associated with a rare but potentially fatal outcome of pituitary apoplexy (PA). An 85-year-old man presented with sudden onset of headache, left eye pain, sensitivity to light, nausea and vomiting. The symptoms started 4 hours after initiation of leuprolide therapy for treatment of recently diagnosed metastatic prostate carcinoma. Radiological imaging of the brain demonstrated a heterogeneously enlarged pituitary gland measuring 19×16×13 mm and T1-hyperintense signal compatible with pituitary haemorrhage...
July 14, 2017: BMJ Case Reports
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