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Chronic serous chorioretinopathy

V Ambiya, R Yogi, A Li, S Shah, C Sarvaiya, P Mehta, C Meyerele, L Wu, R Singh, A Banker, J Chhablani
PurposeThe purpose of the study was to evaluate the role of subfoveal choroidal thickness (CT) measurements as a predictor for the course of central serous chorioretinopathy (CSC).Patients and methodsThirty-eight eyes of 33 patients with CSC were analyzed retrospectively. Key inclusion criteria were naive (acute or recurrent) CSC; a minimum of 12 months of follow up; and the availability of good quality enhanced depth imaging SD-OCT images at each visit. Eyes with changes suggestive of chronic CSC and history of any treatment were excluded...
September 30, 2016: Eye
Talia R Kaden, Anna C S Tan, Leonard Feiner, K Bailey Freund
PURPOSE: To describe the multimodal imaging findings observed unilaterally in a patient with Best disease due to a p.G15D mutation in the BEST1 gene. METHODS: The clinical history of a 62-year-old female patient with unilateral Best disease was reviewed. Retinal findings were documented by clinical examination and multimodal imaging. RESULTS: Posterior segment examination of the patient's right eye demonstrated retinal pigment epithelium hypopigmentation and clumping in the central macula beneath a chronic shallow serous retinal detachment (SRD), confirmed by optical coherence tomography...
September 23, 2016: Retinal Cases & Brief Reports
Kevin C Dietrich
BACKGROUND: Central serous chorioretinopathy (CSC) is usually a self-limiting condition; however, there is potential for recurrence and permanent visual defects. Aviation demands perfect vision to minimize risk to pilots and aircraft. Consequently, this ailment disqualifies pilots and pilots to be. CASE REPORT: A fully trained fighter pilot with 1260 h in fighter airframes has been contending with central serous chorioretinopathy in the right eye over the course of 3 yr...
2016: Aerospace Medicine and Human Performance
Takamasa Kinoshita, Yoshinori Mitamura, Terumi Mori, Kei Akaiwa, Kentaro Semba, Mariko Egawa, Junya Mori, Shozo Sonoda, Taiji Sakamoto
PURPOSE: To determine the structural changes in the choroid after half-dose photodynamic therapy (hPDT) in eyes with chronic central serous chorioretinopathy (CSC). METHODS: This was a retrospective interventional study of 29 eyes of 29 patients who underwent hPDT for chronic CSC with serous retinal detachment (SRD) and were followed for ≥3 months. Enhanced depth imaging optical coherence tomographic (EDI-OCT) images of the subfoveal choroid were converted to binary images...
2016: PloS One
Róbert Gergely, Illés Kovács, Miklós Schneider, Miklós Resch, András Papp, Zsuzsanna Récsán, Zoltán Zsolt Nagy, Mónika Ecsedy
PURPOSE: To evaluate the macular thickness, choroidal thickness, and visual acuity changes in eyes of patients with bilateral chronic central serous chorioretinopathy during eplerenone treatment. METHODS: This prospective clinical trial was conducted on patients with bilateral chronic central serous chorioretinopathy, who had subretinal fluid (SRF) in 1 eye. Twenty-eight patients were treated with 50 mg/day of oral eplerenone for 3 months and were observed for another 3 months...
September 13, 2016: Retina
Pradeep Venkatesh, Rohan Chawla, Koushik Tripathy, Harsh Inder Singh, Ravi Bypareddy
BACKGROUND: Effective therapeutic options are limited for the management of chronic central serous chorioretinopathy (CSCR) complicated by exudative retinal detachments (RD). The authors describe the resolution of one such case following partial thickness scleral resection with mitomycin C. CASE PRESENTATION: This 39-year-old male presented with a unilateral inferior exudative RD in the right eye. There was no history of steroid use either locally or systemically...
2016: Eye and Vision (London, England)
Emin Özmert, Sibel Demirel, Özge Yanık, Figen Batıoğlu
Purpose. To compare the efficacy and safety of subthreshold micropulse yellow wavelength laser (SMYL) and low-fluence photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). Methods. Thirty-three eyes of 30 patients with chronic CSC received either PDT (18 eyes) or SMYL (15 eyes) therapy. Best corrected visual acuity (BCVA), subretinal fluid (SRF) height, and central macular thickness (CMT) were evaluated at the baseline visit and one, three, six, nine, and 12 months after the therapy...
2016: Journal of Ophthalmology
Georges Azar, Benjamin Wolff, Martine Mauget-Faÿsse, Marco Rispoli, Maria-Cristina Savastano, Bruno Lumbroso
PURPOSE: To describe and interpret the features of pachychoroid neovasculopathy (PNV) using optical coherence tomography angiography (OCTA) technique. METHODS: This is an observational case series of patients who presented with PNV. Best-corrected visual acuity (BCVA), anterior segment examination, dilated funduscopic examination, infrared and autofluorescence fundus images and spectral-domain optical coherence tomography (SD-OCT; B-scan, 'en-face' and OCTA) were carried out for all patients...
September 6, 2016: Acta Ophthalmologica
Vikas Ambiya, Abhilash Goud, Annie Mathai, Padmaja Kumari Rani, Jay Chhablani
PURPOSE: To evaluate the role of navigated yellow microsecond laser in treating subfoveal leaks in nonresolving central serous chorioretinopathy (CSC). METHODS: This prospective study included ten eyes of ten consecutive patients with nonresolving CSC with subfoveal leaks. All eyes were treated with 577 nm navigated yellow microsecond laser (5% duty cycle). Key inclusion criteria include a vision loss for a duration of minimum 3 months duration due to focal subfoveal leak on fluorescein angiography...
2016: Clinical Ophthalmology
Federico Corvi, Vittorio Capuano, Lucia Benatti, Francesco Bandello, Eric Souied, Giuseppe Querques
PURPOSE: Chorioretinal folds are undulations that anatomically include the inner choroid, Bruch's membrane, and the retinal pigment epithelium, and secondarily affect the overlying neurosensory retina. We analyzed clinical data and management of six patients diagnosed with chorioretinal folds-related maculopathy with atypical presentations. CASE REPORT: The mean age of the six patients (five women) was 77 years. Best-corrected visual acuity (BCVA) ranged between 20/200 and 20/80...
October 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Pooja H Mehta, Catherine Meyerle, Shobha Sivaprasad, Camiel Boon, Jay Chhablani
PURPOSE: Central serous chorioretinopathy (CSC) management lacks well-defined guidelines given the variable natural history of this disease and the lack of prospective trials. We conducted an online preferred physician practice survey to track international trends and variations in the management of CSC data. METHODS: We designed and distributed an online 27-item questionnaire with secure confidential access to retina specialists with a publication record in CSC...
August 18, 2016: British Journal of Ophthalmology
Frank H P Lai, Danny S Ng, Malini Bakthavatsalam, Vesta C K Chan, Alvin L Young, Fiona O J Luk, Chi Wai Tsang, Mårten E Brelén
PURPOSE: To investigate long-term efficacy and prognostic factors of half-dose photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSCR). DESIGN: Retrospective multicenter interventional case series. METHODS: Patients with chronic CSCR undergoing half-dose PDT between 2005 and 2011 were reviewed. Main outcome measures included resolution of serous retinal detachment (SRD) with single PDT, change in best-corrected visual acuities (BCVAs), and recurrence rate of CSCR at 36 months after PDT...
October 2016: American Journal of Ophthalmology
Jae Hyung Lee, Hae-Young Lopilly Park, Jiwon Baek, Won Ki Lee
PURPOSE: To describe the findings of enhanced depth imaging (EDI) optical coherence tomography (OCT) of the lamina cribrosa (LC) in glaucoma and pachychoroid spectrum diseases associated with peripapillary retinoschisis. DESIGN: Retrospective, observational case series. PARTICIPANTS: A total of 16 patients from 1 institution. METHODS: Detailed medical case histories, optic disc and retinal imaging with EDI using the Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany), and clinical course were reviewed for patients with peripapillary retinoschisis without a known predisposing condition...
October 2016: Ophthalmology
Won June Lee, Jung Wook Lee, Seung Hun Park, Byung Ro Lee
AIMS: To evaluate the variable depth tomographic features of choroidal vasculature in acute and chronic central serous chorioretinopathy (CSC) using swept source optical coherence tomography (SS-OCT) en face imaging. METHODS: We retrospectively reviewed the en face SS-OCT images of 29 patients that presented with acute (12 eyes) or chronic (17 eyes) CSC. All of the patient eyes underwent 6×6 macular scans with SS-OCT (DRI OCT-1, Topcon, Tokyo, Japan), fluorescein angiography and indocyanine green angiography...
August 2, 2016: British Journal of Ophthalmology
Yao Wang, Zhi-Qing Chen, Wei Wang, Xiao-Yun Fang
Purpose. To investigate the prevalence and characteristics of focal choroidal excavation (FCE) concurrent with central serous chorioretinopathy (CSC) using multimodal imaging. Methods. This was a retrospective single-institution study. Clinical features and multimodal imaging findings were analyzed in eyes with CSC and FCEs, using imaging methods including optical coherence tomography (OCT), OCT angiography (OCTA), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF), and multispectral imaging...
2016: Journal of Ophthalmology
Cheng-Kuo Cheng, Chun-Kai Chang, Chi-Hsien Peng
PURPOSE: To compare the efficacy and the detrimental effects of half-drug dose and half-laser light fluence of photodynamic therapy (PDT) for the treatment of chronic central serous chorioretinopathy. DESIGN: We conducted a prospective randomized, observer-masked comparison study. METHODS: Forty eyes (40 patients) with chronic central serous chorioretinopathy were enrolled in this study and were equally divided into 2 groups. The first (half-dose) group received only half the standard dose of verteporfin infusion (3 mg/m) and were irradiated by the standard 83 seconds of laser light (50 J/cm) for the PDT treatment; the second (half-fluence) group received the standard dose of verteporfin infusion (6 mg/m) and were irradiated by only 42 seconds of laser light (25 J/cm)...
July 14, 2016: Retina
Elon H C van Dijk, Michiel F Nijhoff, Eiko K de Jong, Onno C Meijer, Aiko P J de Vries, Camiel J F Boon
PURPOSE: To describe ophthalmological characteristics of 13 patients with primary hyperaldosteronism (PA). METHODS: Cross-sectional study. All patients underwent extensive ophthalmological examination. RESULTS: Thirteen PA patients (9 male, 4 female) were diagnosed with arterial hypertension for 11.0 ± 11.2 years. Ophthalmological imaging revealed macular serous subretinal fluid (SRF) on optical coherence tomography in 2 patients (15 %)...
July 8, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Serra Arf, Mumin Hocaoglu, Isil Sayman Muslubas, Murat Karacorlu
The purpose of the study was to evaluate the effect of reduced-fluence photodynamic therapy (RFPDT) for chronic central serous chorioretinopathy (CSC) associated with serous retinal detachment (SRD) and fovea-involving pigment epithelial detachment (PED). Ten eyes of ten patients with chronic CSC associated with combined SRD and PED involving the fovea were included. RFPDT was applied to the hyperfluorescent area identified at the mid-to-late phase of indocyanine green angiography, which indicated the area of leakage...
July 8, 2016: International Ophthalmology
P Scholz, L Altay, S Fauser
PurposeTo compare the short-term treatment outcome of the 577 nm subthreshold micropulse laser (SML) and half-dose photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC) and persistent subretinal fluid (SRF).MethodsThis retrospective study included 100 eyes of 100 consecutive patients who were treated with the 577 nm SML (Supra Scan, Quantel Medical) (n=42) or half-dose PDT (n=58) for cCSC. The treatment was applied at the leakage sites in the fluorescein and indocyanine green angiography...
July 8, 2016: Eye
Zhu Liang, Chenbin Tian
OBJECTIVE: The aim of this prospective observational study was to evaluate the effects of acupuncture at Erjian on chronic central serous chorioretinopathy (CSC). STUDY DESIGN: Prospective case series. METHODS: Nine patients with chronic CSC were recruited and each patient received 12 sessions of acupuncture treatment. Subjective symptom measures included complications, best-corrected visual acuity (BCVA), fluorescein leakage (via fluorescein fundus angiography), and central subfield foveal subretinal fluid (on optical coherence tomography (OCT)) at 3 months...
July 7, 2016: Acupuncture in Medicine: Journal of the British Medical Acupuncture Society
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