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Chronic serous chorioretinopathy

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https://www.readbyqxmd.com/read/28323591/treatment-and-monitoring-of-central-serous-chorioretinopathy-in-pilots
#1
Ari Shinojima, Ryusaburo Mori, Kyoko Fujita, Mitsuko Yuzawa
BACKGROUND: Central serous chorioretinopathy (CSC), which has the characteristics of a serous retinal detachment (SRD) in the macular area, affects mostly men in the 30- to 50-yr age range. Some patients have persistent SRD, which may cause retinal thinning and photoreceptor impairment. CSC symptoms are gradual vision loss and/or metamorphopsia. Some commercial airline pilots are concerned about CSC symptoms, which can disqualify them from flying for months and can also reoccur. Thus, careful monitoring and treatment of CSC are critical for pilots, especially those with chronic or recurrent CSC...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28283732/comparison-of-half-dose-photodynamic-therapy-and-689-nm-laser-treatment-in-eyes-with-chronic-central-serous-chorioretinopathy
#2
Andrea Russo, Raffaele Turano, Francesco Morescalchi, Elena Gambicorti, Anna Cancarini, Sarah Duse, Ciro Costagliola, Francesco Semeraro
PURPOSE: To compare visual and anatomical outcomes between half-dose photodynamic therapy (hd-PDT) and 689 nm laser therapy (689-LT) in chronic central serous chorioretinopathy (CSC). METHODS: Forty eyes of 40 patients with symptomatic chronic CSC were randomized in a 1:1 ratio to receive either hd-PDT or 689-LT delivering 95 J/cm(2) via an intensity application of 805 mW/cm(2) over 118 s. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography findings were compared between the two treatment groups...
March 10, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28277988/therapy-rationale-for-mineralocorticoid-receptor-antagonists-acetazolamide-and-a-switch-of-therapy-in-nonresponders-in-central-serous-chorioretinopathy
#3
Anne Rübsam, Claudia E Thieme, Juliane Schlomberg, Sibylle Winterhalter, Bert Müller, Antonia M Joussen, Nicole Stübiger
PURPOSE: To evaluate the efficacy of mineralocorticoid-receptor antagonists in comparison to acetazolamide and observation in the treatment of central serous chorioretinopathy. METHODS: Retrospective, interventional cohort study on 93 patients with acute or chronic central serous chorioretinopathy (37 patients: acetazolamide group, 20 patients: mineralocorticoid-receptor antagonist group, 8 patients: observation group, and 27 patients with a therapy switch between both medications)...
March 9, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28267114/optical-coherence-tomography-angiography-of-flat-irregular-pigment-epithelium-detachment-in-chronic-central-serous-chorioretinopathy
#4
Elodie Bousquet, Sophie Bonnin, Sarah Mrejen, Valérie Krivosic, Ramin Tadayoni, Alain Gaudric
PURPOSE: To assess the rate of choroidal neovascularization (CNV) detected by optical coherence tomography angiography (OCTA) in flat irregular pigment epithelium detachment (PED) in chronic central serous chorioretinopathy. METHODS: Data on all consecutive patients with chronic central serous chorioretinopathy who underwent OCTA over a 1-year period were reviewed. The presence of flat irregular PED, which was defined as an irregular elevation of the retinal pigment epithelium allowing the visualization of a distinct Bruch's membrane was assessed on high-resolution OCT B-scan...
March 3, 2017: Retina
https://www.readbyqxmd.com/read/28239828/the-relation-of-the-serum-aldosterone-level-and-central-serous-chorioretinopathy-a-pilot-study
#5
Q Gong, X-H Sun, S-T Yuan, Q-H Liu
OBJECTIVE: The aim of this study was to investigate the serum aldosterone level and abnormal levels of mineral corticoid in patients with the central serous chorioretinopathy (CSC). PATIENTS AND METHODS: All recruited patients with CSC received fundus fluorescein angiography (FFA), enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) and serum aldosterone assay. The patients were classified into spontaneously resolved group and unresolved group according to a 3-months follow-up of Optical Coherence Tomography (OCT) examination...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28181178/the-ocular-manifestations-of-drugs-used-to-treat-multiple-sclerosis
#6
REVIEW
Gregory Heath, Archana Airody, Richard Peter Gale
Recent times have seen an increase in the number of options to treat multiple sclerosis. Ocular manifestations of multiple sclerosis are well known to treating physicians; however, the medications used to treat multiple sclerosis can also have ocular side effects. This review article focuses on the ocular manifestations of corticosteroids and disease-modifying agents such as interferon, fingolomod, natalizumab, alemtuzumab and mitoxantron used to treat the disease. The ocular manifestations of multiple sclerosis treatments can be varied depending on the drug used, and include retinopathy, chronic central serous chorioretinopathy, macular oedema, Graves' ophthalmopathy and cortical blindness...
February 8, 2017: Drugs
https://www.readbyqxmd.com/read/28171877/a-multicenter-randomized-controlled-study-of-antioxidant-supplementation-with-lutein-for-chronic-central-serous-chorioretinopathy
#7
Ari Shinojima, Miki Sawa, Tetsuju Sekiryu, Yuji Oshima, Ryusaburo Mori, Chikako Hara, Yukinori Sugano, Aki Kato, Hitomi Asato, Mitsuko Yuzawa, Fumi Gomi, Yuichiro Ogura, Tatsuro Ishibashi, Tomoaki Nanri, Tsutomu Yasukawa
PURPOSE: To investigate functional and morphological changes in patients with chronic central serous chorioretinopathy after supplementation with antioxidants containing lutein or a placebo. PROCEDURES: One hundred eyes of 100 patients were randomly divided into 2 groups, one taking tablets with lutein plus other antioxidants and the other taking a placebo for 6 months. Best-corrected visual acuity (BCVA) and the subfoveal fluid height on optical coherence tomography were measured...
February 8, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28171871/effect-of-photodynamic-therapy-on-optical-coherence-tomography-angiography-in-eyes-with-chronic-central-serous-chorioretinopathy
#8
Yishuang Xu, Yu Su, Lu Li, Hang Qi, Hongmei Zheng, Changzheng Chen
PURPOSE: To analyze the use of optical coherence tomography angiography (OCTA) in order to observe the changes in chronic central serous chorioretinopathy (CCSC) after half-dose photodynamic therapy (PDT). METHODS: This is a retrospective study evaluating an imaging technique in a cohort of patients. Fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA) (Heidelberg Spectralis, Heidelberg, Germany), OCT, and OCTA with the split-spectrum amplitude-decorrelation angiography algorithm (XR Optovue, Fremont, CA, USA) were performed prior to half-dose PDT...
February 8, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28154953/half-dose-photodynamic-therapy-for-chronic-central-serous-chorioretinopathy-evaluated-by-focal-macular-electroretinograms
#9
Kazuhiro Oiwa, Keiko Kataoka, Ruka Maruko, Shinji Ueno, Yasuki Ito, Hiroko Terasaki
PURPOSE: To evaluate the effect of half-dose verteporfin photodynamic therapy (hPDT) on the physiology of the macula determined by focal macular electroretinograms (FMERGs) in eyes with chronic central serous chorioretinopathy (CSC). METHODS: Fourteen eyes of 13 patients with chronic CSC were treated with hPDT. The best-corrected visual acuity (BCVA) was measured, and optical coherence tomography (OCT) and FMERGs were performed at the baseline, and at 4 days, 1, 3, 6, and 12 months after the hPDT...
February 2, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058163/clinical-features-and-course-of-patients-with-peripheral-exudative-hemorrhagic-chorioretinopathy
#10
Zafer Cebeci, Yasemin Dere, Şerife Bayraktar, Samuray Tuncer, Nur Kır
OBJECTIVES: To evaluate the clinical characteristics of patients who were followed in our clinic with the diagnosis of peripheral exudative hemorrhagic chorioretinopathy (PEHC). MATERIALS AND METHODS: Medical records of 12 patients who were diagnosed with PEHC in İstanbul University İstanbul Faculty of Medicine, Department of Ophthalmology between July 2006 and June 2014 were reviewed retrospectively. RESULTS: This study included 21 eyes of 12 patients...
October 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28053499/chronic-central-serous-chorioretinopathy-long-term-follow-up-and-vision-related-quality-of-life
#11
Myrte B Breukink, Alexander Jm Dingemans, Anneke I den Hollander, Jan Ee Keunen, Robert E MacLaren, Sascha Fauser, Giuseppe Querques, Carel B Hoyng, Susan M Downes, Camiel Jf Boon
PURPOSE: To describe the clinical findings and long-term outcome of patients with chronic central serous chorioretinopathy (cCSC). MATERIALS AND METHODS: This was a retrospective case series in 52 eyes of 36 patients with a follow-up period of at least 1 year. Extensive ophthalmic examination and a validated questionnaire concerning vision-related quality of life (National Eye Institute Visual Function Questionnaire [NEI-VFQ]-39) were analyzed. RESULTS: Mean visual acuity showed a significant decline over time of 0...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28009402/choroidal-characteristics-of-acute-and-chronic-central-serous-chorioretinopathy-using-enhanced-depth-imaging-optical-coherence-tomography
#12
Jorge Ruiz-Medrano, Marco Pellegrini, Matteo G Cereda, Mario Cigada, Giovanni Staurenghi
PURPOSE: Central serous chorioretinopathy (CSC) is an idiopathic disorder characterized by serous detachments of the neurosensory retina and/or the retinal pigment epithelium affecting the macular area in the majority of cases. The objective of this study was to describe choroidal findings in patients with acute and chronic CSC based on enhanced depth imaging optical coherence tomography analysis. METHODS: This is a cross-sectional, noninterventional study performed at Luigi Sacco University Hospital of Milan...
November 18, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27997459/short-term-findings-on-optical-coherence-tomography-and-microperimetry-in-chronic-central-serous-chorioretinopathy-patients-treated-with-half-dose-photodynamic-therapy
#13
Elon H C van Dijk, Greet Dijkman, Thomas Theelen, Carel B Hoyng, Camiel J F Boon
PURPOSE: To assess the short-term outcome of and possible temporary vision loss after half-dose verteporfin photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC). METHODS: In this prospective study, 14 eyes of 13 cCSC patients who underwent half-dose PDT were included. Patients received spectral-domain optical coherence tomography (OCT) imaging and microperimetry before PDT on the day of treatment and 1 week after treatment...
December 16, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27902539/cystoid-macular-edema-and-cystoid-macular-degeneration-as-a-result-of-multiple-pathogenic-factors-in-the-setting-of-central-serous-chorioretinopathy
#14
Polina Astroz, Chandrakumar Balaratnasingam, Lawrence A Yannuzzi
PURPOSE: To report the pathogenic factors that account for cystoid macular edema and cystoid macular degeneration in chronic central serous chorioretinopathy (CSC). METHODS: The clinical course and multimodal imaging findings, including fundus color photography, fundus autofluorescence, spectral-domain optical coherence tomography, and fluorescein angiography, of one eye with cystoid macular edema due to chronic CSC was documented. RESULTS: A 44-year old woman with a history of chronic CSC presented with progressive visual decline in the right eye...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27826180/preliminary-analysis-of-the-relationship-between-serum-lutein-and-zeaxanthin-levels-and-macular-pigment-optical-density
#15
Shigeto Fujimura, Kohei Ueda, Yoko Nomura, Yasuo Yanagi
PURPOSE: To assess the relationship between combined serum lutein and zeaxanthin (L+Z) concentration and macular pigment optical density (MPOD), and to investigate the effect of L+Z+docosahexaenoic acid (DHA) dietary supplementation on the spatial distribution of MPOD. METHODS: Twenty healthy fellow eyes with unilateral wet age-related macular degeneration or chronic central serous chorioretinopathy were included. All participants received a dietary supplement for 6 months that contained 20 mg L, 1 mg Z, and 200 mg DHA...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27813516/comment-on-comparison-of-subthreshold-micropulse-laser-577%C3%A2-nm-treatment-and-half-dose-photodynamic-therapy-in-patients-with-chronic-central-serous-chorioretinopathy
#16
https://www.readbyqxmd.com/read/27799060/mefloquine-associated-dizziness-diplopia-and-central-serous-chorioretinopathy-a-case-report
#17
Manish Jain, Remington L Nevin, Iajaz Ahmed
BACKGROUND: Many acute and chronic neurological sequelae from the quinoline derivative antimalarial drug mefloquine, including dizziness and effects on the visual system such as diplopia and blurred vision, may be attributable to focal central nervous system toxicity. Maculopathy has also been reported with use of mefloquine, although the mechanism of this effect has remained unclear. Identification of a common mechanism of toxicity plausibly underlying these visual and non-visual effects may provide broader insights into the acute and chronic neuropsychiatric effects of this and other quinoline antimalarial drugs...
October 31, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27780174/clinical-spectrum-of-macular-foveal-capillaries-evaluated-with-optical-coherence-tomography-angiography
#18
Maria V Cicinelli, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Ilaria Zucchiatti, Vincenzo Scorcia, Francesco Bandello, Giuseppe Querques
PURPOSE: To describe macular-foveal capillaries (MFC) by means of optical coherence tomography angiography and to identify the clinical spectrum of this angiographic feature. METHODS: Patients with MFC presenting at the Medical Retina & Imaging Unit of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited. Patients underwent a complete ophthalmologic examination that included slit-lamp examination, fundus examination, measurement of best-corrected visual acuity, fundus autofluorescence, and spectral-domain optical coherence tomography (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany)...
March 2017: Retina
https://www.readbyqxmd.com/read/27689964/subfoveal-choroidal-thickness-as-a-predictor-of-central-serous-chorioretinopathy
#19
V Ambiya, R Yogi, A Li, S Shah, C Sarvaiya, P Mehta, C Meyerele, L Wu, R Singh, A Banker, J Chhablani
PurposeThe purpose of the study was to evaluate the role of subfoveal choroidal thickness (CT) measurements as a predictor for the course of central serous chorioretinopathy (CSC).Patients and methodsThirty-eight eyes of 33 patients with CSC were analyzed retrospectively. Key inclusion criteria were naive (acute or recurrent) CSC; a minimum of 12 months of follow up; and the availability of good quality enhanced depth imaging SD-OCT images at each visit. Eyes with changes suggestive of chronic CSC and history of any treatment were excluded...
December 2016: Eye
https://www.readbyqxmd.com/read/27668499/unilateral-best-disease-a-case-report
#20
Talia R Kaden, Anna C S Tan, Leonard Feiner, K Bailey Freund
PURPOSE: To describe the multimodal imaging findings observed unilaterally in a patient with Best disease due to a p.G15D mutation in the BEST1 gene. METHODS: The clinical history of a 62-year-old female patient with unilateral Best disease was reviewed. Retinal findings were documented by clinical examination and multimodal imaging. RESULTS: Posterior segment examination of the patient's right eye demonstrated retinal pigment epithelium hypopigmentation and clumping in the central macula beneath a chronic shallow serous retinal detachment (SRD), confirmed by optical coherence tomography...
January 2017: Retinal Cases & Brief Reports
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