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Chronic serous chorioretinopathy

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https://www.readbyqxmd.com/read/29016451/concurrent-idiopathic-macular-telangiectasia-type-2-and-central-serous-chorioretinopathy
#1
Alexandre Matet, Suzanne Yzer, Emily Y Chew, Alejandra Daruich, Francine Behar-Cohen, Richard F Spaide
PURPOSE: To describe cases presenting with features of idiopathic macular telangiectasia (MacTel) Type 2 and central serous chorioretinopathy (CSC). METHODS: Databases from four tertiary retina centers were searched for cases copresenting CSC and MacTel Type 2. RESULTS: Five cases were identified (4 men, 1 woman; mean age: 67.2 years). Four patients were referred for chronic or nonresolving CSC, and the diagnosis of MacTel Type 2 was made based on multimodal imaging findings...
October 9, 2017: Retina
https://www.readbyqxmd.com/read/28860700/changes-of-outer-retinal-microstructures-after-photodynamic-therapy-for-chronic-central-serous-chorioretinopathy
#2
Kimiko Shimizu, Yohei Hashimoto, Keiko Azuma, Yoko Nomura, Ryo Obata, Hidenori Takahashi, Yasuo Yanagi
PURPOSE: To evaluate the morphological changes in retinal microstructures following modified photodynamic therapy (PDT) for chronic central serous chorioretinopathy. SUBJECTS AND METHODS: Retrospective study of 21 consecutive eyes (age, 59±8.0 years [mean ± SD]) of 21 patients with chronic central serous chorioretinopathy. Inner foveal thickness (the distance between the internal limiting membrane and external limiting membrane), photoreceptor outer segment (PROS) length at the point without serous retinal detachment and choroidal thickness were assessed with enhanced depth imaging optical coherence tomography before treatment and at 1, 3 and 6 months after modified PDT...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28832738/multimodal-assessment-of-patients-with-chronic-central-serous-chorioretinopathy
#3
COMPARATIVE STUDY
Karlos Ítalo Souza Viana, Pedro M Souza Leão, Letícia Fernandes, Rubens Siqueira, Jefferson Ribeiro, Rodrigo Jorge
PURPOSE: To examine differences between fluorescein angiography (FA) and indocyanine green angiography (ICG) findings in patients with chronic central serous chorioretinopathy (CSC), comparing these with optical coherence tomography (OCT) findings. METHODS: Ten consecutive patients with chronic CSC (19 eyes; 7 men; mean age, 50.7 ± 8.4 years) underwent multimodal evaluation that included FA, ICG, and OCT (Spectralis HRA-OCT, Heidelberg Engineering, Heidelberg, Germany)...
June 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28831603/functional-and-morphological-outcome-in-patients-with-chronic-central-serous-chorioretinopathy-treated-by-subthreshold-micropulse-laser
#4
Maciej Gawęcki, Agnieszka Jaszczuk-Maciejewska, Anna Jurska-Jaśko, Andrzej Grzybowski
BACKGROUND: Chronic central serous chorioretinopathy is a serious therapeutic problem as it may lead to significant visual impairment. The aim of this retrospective study is to evaluate functional and morphological effects, as well as factors influencing visual outcome in patients treated by subthreshold micropulse laser. METHODS: Fifty-one eyes with chronic central serous chorioretinopathy lasting longer than 4 months (18 months on average) underwent up to two sessions of subtreshold micropulse laser treatment...
August 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28814876/neutrophil-lymphocyte-ratio-and-mean-platelet-volume-in-central-serous-chorioretinopathy
#5
Muhammet Kazim Erol, Ayse Balkarli, Ozgur Yucel, Yusuf Akar, Berna Dogan, Elcin Suren
PURPOSE: This study aimed to evaluate mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) values and their relationship with clinical findings in patients with central serous chorioretinopathy (CSCR). METHODS: Overall, 87 patients fulfilling inclusion criteria and 320 age- and sex-matched healthy individuals as controls were included in the study. The CSCR patients (n=87) were classified into 2 groups as acute CSCR (group 1, n=43) and chronic CSCR (group 2, n=44)...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28798899/diagnosed-a-patient-with-central-serous-chorioretinopathy-now-what-management-of-central-serous-chorioretinopathy
#6
Brian E Goldhagen, Raquel Goldhardt
PURPOSE OF REVIEW WHAT IS THE GOAL OF YOUR PAPER? WHAT QUESTIONS DID YOU SEEK TO ANSWER?: The goal of this paper is to provide a comprehensive review of the management options for central serous chorioretinopathy (CSCR). RECENT FINDINGS SUMMARIZE THE LATEST RESEARCH ON YOUR TOPIC: The majority of cases of acute CSCR may be managed with observation and cessation of corticosteroids, if possible, as well as life-style modifications including stress reduction and control of hypertension...
June 2017: Current Ophthalmology Reports
https://www.readbyqxmd.com/read/28797227/changes-in-macular-sensitivity-after-half-dose-photodynamic-therapy-for-chronic-central-serous-chorioretinopathy
#7
Alp Atik, Yijun Hu, Honghua Yu, Chun Yang, Bin Cai, Yijing Tao, Dongli Li, Yan Chen, Li Lu, Guodong Li, Ling Yuan
BACKGROUND: To evaluate the macular sensitivity changes after half-dose photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR). METHODS: Eighteen patients (26 eyes) with chronic CSCR were recruited in the same hospital between April 2011 and December 2012. All patients were treated with one session of half-dose PDT after complete ophthalmic examination. Macular sensitivity examination was performed at baseline and 1, 3 and 6 months post-treatment...
August 10, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28791061/visual-and-anatomical-outcomes-of-spironolactone-therapy-in-patients-with-chronic-central-serous-chorioretinopathy
#8
Khalil Ghasemi Falavarjani, Anahita Amirsardari, Abbas Habibi, Acieh Eshaghi, Shohreh Bakhti, Kaveh Abri Aghdam
PURPOSE: To evaluate the effect of spironolactone on chronic central serous chorioretinopathy (CSC). METHODS: In this prospective interventional case series, patients with chronic CSC were treated with spironolactone (25 mg daily) for at least 6 weeks. If the subretinal fluid (SRF) had not completely resolved by this time, treatment was continued, and the dosage was increased to 25 mg twice daily. Primary outcome measure was the change in maximum SRF height at the final follow-up visit, as detected by optical coherence tomography...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28774289/acute-uveal-effusion-during-phacoemulsification-with-preoperative-central-serous-chorioretinopathy-a-case-report
#9
Ruiqi Chang, Yu Du, Zhou Peng, Yi Lu, Xiangjia Zhu
BACKGROUND: We report a case of acute uveal effusion during phacoemulsification in an eye with preoperative chronic central serous chorioretinopathy (CSC). CASE PRESENTATION: A 55-year-old man with a history of chronic CSC for >18 months presented with bilateral opaque lenses. A preoperative ophthalmic examination showed suspected lenticonus and risky anatomical features, including a thick ciliary body, and anterior rotation of the ciliary process and iris root in both eyes...
August 3, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28742138/long-term-prognostic-factors-of-chronic-central-serous-chorioretinopathy-after-half-dose-photodynamic-therapy-a-3-year-follow-up-study
#10
Fuminori Haga, Ruka Maruko, Chiaki Sato, Keiko Kataoka, Yasuki Ito, Hiroko Terasaki
PURPOSE: To evaluate the long-term efficacy and factors involved in the recurrence and persistence of subretinal fluid (SRF) after half-dose photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). METHODS: In this retrospective observational case series, 79 eyes (73 patients) with chronic CSC were treated with half-dose PDT and followed up for at least 3 years. They were divided into successful (64 eyes) and unsuccessful (15 eyes) groups based on SRF absorption and disease recurrence after one PDT session...
2017: PloS One
https://www.readbyqxmd.com/read/28728183/early-focal-laser-photocoagulation-in-acute-central-serous-chorioretinopathy-a-prospective-randomized-study
#11
RANDOMIZED CONTROLLED TRIAL
Vikas Ambiya, Mitali Khodani, Abhilash Goud, Raja Narayanan, Mudit Tyagi, Padmaja Kumari Rani, Jay Chhablani
BACKGROUND AND OBJECTIVE: To evaluate the role of early focal laser photocoagulation in acute central serous chorioretinopathy (CSC). PATIENTS AND METHODS: A total of 58 eyes with acute naïve CSC (less than 2 months' duration) with focal leak on fundus fluorescein angiography (FFA) were randomized into either a laser or a sham laser group. Eyes with chronic CSC and subfoveal leak were excluded. Visual acuity assessment, microperimetry, optical coherence tomography, and FFA were done at baseline, 1 month (minus FFA), 3 months, and 6 months after treatment...
July 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28699928/anti-vegf-therapy-versus-photodynamic-therapy-in-the-treatment-of-choroidal-neovascularization-secondary-to-central-serous-chorioretinopathy
#12
Enrico Peiretti, Giulia Caminiti, Rita Serra, Lea Querques, Riccardo Pertile, Giuseppe Querques
PURPOSE: To evaluate the efficacy of photodynamic therapy (PDT) compared with intravitreal vascular endothelial growth factor (VEGF) inhibitors alone or combined with PDT in the treatment of choroidal neovascularization (CNV) secondary to chronic central serous chorioretinopathy (CSCR). METHODS: Retrospective study of a consecutive series of 34 white patients (34 eyes) with angiographic evidence of choroidal neovascularization secondary to chronic central serous chorioretinopathy, divided into two groups followed for at least 12 months: 16 were treated with full fluence PDT (PDT group) and 18 with vascular endothelial growth factor inhibitors (intravitreal [IVT] group)...
July 7, 2017: Retina
https://www.readbyqxmd.com/read/28674835/photodynamic-therapy-in-chronic-central-serous-chorioretinopathy-with-subretinal-fluid-outside-the-fovea
#13
Elon H C van Dijk, Greet Dijkman, Camiel J F Boon
PURPOSE: To assess the efficacy of photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC), in whom subretinal fluid (SRF) was solely present outside the foveal area. METHODS: In this retrospective study, 16 eyes of 15 cCSC patients who received half-dose PDT because of notable subjective visual complaints due to the presence of extrafoveal SRF, were included. An ophthalmic examination was performed before treatment, including Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, applanation tonometry, slit-lamp examination, and indirect ophthalmoscopy, followed by multimodal imaging, including fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography (OCT), enhanced-depth imaging OCT of the choroid, fluorescein angiography, and indocyanine green angiography...
July 3, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28671968/systemic-complement-activation-in-central-serous-chorioretinopathy
#14
Elon H C van Dijk, Roula Tsonaka, Ngaisah Klar-Mohamad, Diana Wouters, Aiko P J de Vries, Eiko K de Jong, Cees van Kooten, Camiel J F Boon
PURPOSE: A clear link between several variants in genes involved in the complement system and chronic central serous chorioretinopathy (CSC) has been described. In age-related macular degeneration, a disease that shows clinical features that overlap with CSC, both genetic risk factors and systemic activation of the complement system have previously been found. In this case-control study, we assessed whether there is evidence of either systemic activation or inhibition of the complement system in patients with chronic CSC...
2017: PloS One
https://www.readbyqxmd.com/read/28653813/eplerenone-for-chronic-central-serous-chorioretinopathy-a-randomized-controlled-prospective-study
#15
Roy Schwartz, Zohar Habot-Wilner, Michael R Martinez, Amir Nutman, Dafna Goldenberg, Shai Cohen, Shiri Shulman, Hanan Guzner-Gur, Anat Loewenstein, Michaella Goldstein
PURPOSE: To evaluate the efficacy and safety of eplerenone for chronic nonresolving central serous chorioretinopathy (CSC). METHODS: Prospective, double-blind, randomized placebo-controlled study. Nineteen eyes of 17 patients with persistent subretinal fluid (SRF) due to CSC were enrolled and randomized to receive eplerenone 50 mg/day or placebo for 3 months, followed by a 3-month follow-up. The main outcome measure was change in SRF from baseline to 3 months of treatment...
June 27, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28626824/atypical-chronic-central-serous-chorioretinopathy-with-cystoid-macular-edema-therapeutic-response-to-medical-and-laser-therapy
#16
Jiun L Do, Lisa C Olmos de Koo, Hossein Ameri
PURPOSE: To describe an atypical case of chronic central serous chorioretinopathy (CSCR). METHODS: A 58-year-old man with longstanding, bilateral visual impairment was self-referred for a second opinion. RESULTS: Findings by direct ophthalmoscopy, optical coherence tomography, fluorescein angiography, and fundus autofluorescence (FAF) were suggestive of atypical, chronic CSCR. Treatment with oral anti-mineralocorticoids resulted in moderate improvement, and photodynamic therapy (PDT) had minimal effect...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28616258/the-comparison-of-multimodal-imaging-findings-of-central-serous-chorioretinopathy-patients-in-regard-to-the-early-anatomically-treatment-response-to-half-fluence-photodynamic-therapy-a-retrospective-case-control-study
#17
Abdullah Ozkaya, Ruveyde Garip, Zeynep Alkin, Muhittin Taskapili
BACKGROUND: To compare the multimodal imaging findings of chronic central serous chorioretinopathy (CSC) patients who are good or poor responders to low-fluence photodynamic therapy (PDT). METHODS: Retrospective, interventional comparative study. The CSC patients who were admitted to our clinic for the first time between January 2013 and December 2015 were included in the study. Patients were treated with PDT only if they did not show any sign of resolution after at least 6 months from the initial signs of the disease...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28514814/-possibilities-and-limitations-of-oct-angiography-in-patients-with-central-serous-chorioretinopathy
#18
B Cakir, M Reich, S J Lang, A Bühler, A Stahl, D Böhringer, H Agostini, C Lange
Purpose Central serous chorioretinopathy (CSC) is a commonly acquired maculopathy characterized by the accumulation of subretinal fluid at the posterior pole. This study aims to analyze optical coherence tomography angiography (OCTA) findings in patients with acute and chronic CSC and to compare them to conventional imaging methods. Methods A series of 43 consecutive eyes of 29 patients diagnosed with CSC and 18 eyes of 9 healthy control subjects were included in this retrospective study. The OCTA images were assessed and compared to conventional fluorescence (FAG) and indocyanine green angiography (ICG)...
May 17, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28497336/the-overlapping-spectrum-of-flat-irregular-pigment-epithelial-detachment-investigated-by-optical-coherence-tomography-angiography
#19
Francesco Pichi, Mariachiara Morara, Chiara Veronese, Antonio P Ciardella
PURPOSE: To describe the OCT angiography characteristics of flat irregular pigment epithelial detachments (PEDs), an overlapping tomographic feature of various macular disorders. METHODS: Consecutive patients with a dimpled retinal pigment epithelium profile on OCT, referred for a second opinion, were enrolled. Fluorescein (FA) and indocyanine green angiography (ICGA) were performed in all patients and compared to previous examinations, when available. In all patients, enhanced depth imaging-OCT and OCT angiography were performed upon referral and at subsequent follow-ups...
May 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28489695/classification-of-haller-vessel-arrangements-in-acute-and-chronic-central-serous-chorioretinopathy-imaged-with-en-face-optical-coherence-tomography
#20
Maria C Savastano, Kunal K Dansingani, Marco Rispoli, Gianni Virgili, Alfonso Savastano, K Bailey Freund, Bruno Lumbroso
PURPOSE: To compare the prevailing patterns of Haller vessel arrangements at the posterior pole between healthy eyes and those with central serous chorioretinopathy (CSC) using en face optical coherence tomography. METHODS: Eyes of normal subjects and patients with acute or chronic CSC underwent optical coherence tomography imaging (RTVue 100; Optovue Inc, Fremont, CA). En face sections at the level of the Haller layer were classified by two masked graders into five mutually exclusive morphologic categories (temporal herringbone, branched from below, laterally diagonal, double arcuate, and reticular)...
May 9, 2017: Retina
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