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Pregnancy sleep apnea

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https://www.readbyqxmd.com/read/29029347/childhood-health-and-educational-outcomes-associated-with-maternal-sleep-apnea-a-population-record-linkage-study
#1
Yu Sun Bin, Peter A Cistulli, Christine L Roberts, Jane B Ford
Objectives: Sleep apnea in pregnancy is known to adversely affect birth outcomes. Whether in utero exposure to maternal sleep apnea is associated with long-term childhood consequences is unclear. Methods: Population-based longitudinal study of singleton infants born during 2002 to 2012 was conducted using linked birth, hospital, death, developmental, and educational records from New South Wales, Australia. Maternal sleep apnea during pregnancy was identified from hospital records...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/28926639/risk-of-glucose-intolerance-and-gestational-diabetes-mellitus-in-relation-to-maternal-habitual-snoring-during-early-pregnancy
#2
Chunfang Qiu, Wayne Lawrence, Bizu Gelaye, Lee Stoner, Ihunnaya O Frederick, Daniel A Enquobahrie, Tanya K Sorensen, Michelle A Williams
BACKGROUND: Obstructive sleep apnea (OSA) or habitual snoring is known to be associated with impaired glucose tolerance and type 2 diabetes among both men and non-pregnant women. We examined the association of habitual snoring during early pregnancy with risk of impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM). METHODS: A cohort of 1,579 women was interviewed during early pregnancy. We collected information about snoring frequency during early pregnancy...
2017: PloS One
https://www.readbyqxmd.com/read/28845959/sleep-disorders-restless-legs-syndrome
#3
Deepa Burman
Restless legs syndrome (RLS) is a common disorder that often is underdiagnosed and undertreated. Patients with RLS describe an urge to move their legs, especially in the evenings and during periods of inactivity. The prevalence of clinically significant RLS is approximately 2% to 3% in adults in Europe and North America. RLS can be an independent disorder or may occur in conjunction with other conditions (eg, iron deficiency, pregnancy, chronic renal failure). Diagnosis is based on clinical history. Routine polysomnography typically is not recommended unless there is suspicion of other sleep disorders (eg, obstructive sleep apnea)...
September 2017: FP Essentials
https://www.readbyqxmd.com/read/28841741/-obstructive-sleep-apnea-syndrome-and-pregnancy
#4
M Orth, T Schäfer, S Schiermeier, K Rasche
No abstract text is available yet for this article.
August 25, 2017: Pneumologie
https://www.readbyqxmd.com/read/28828052/the-role-of-obstructive-sleep-apnea-in-developing-gestational-hypertension-and-preeclampsia
#5
Laura Lungeanu-Juravle, Natalia Patrascu, Oana Claudia Deleanu, Mircea Cinteza
Gestational hypertension and preeclampsia are the most frequent medical complications in pregnancy and major causes of maternal and fetal morbidity and mortality. It is also known that these conditions are associated with a long term increased cardiovascular global risk for these young women. Obstructive sleep apnea (OSA) seems to be not only a frequent pathology associated with pregnancy but also an independent factor for developing gestational hypertension. It is well known the relationship between gestational hypertension, preeclampsia and intrauterine growth restriction of the foetus so the outcomes of this pathologies are important for both mother and child...
December 2016: Mædica
https://www.readbyqxmd.com/read/28796676/sleep-disorder-diagnosis-during-pregnancy-and-risk-of-preterm-birth
#6
Jennifer N Felder, Rebecca J Baer, Larry Rand, Laura L Jelliffe-Pawlowski, Aric A Prather
OBJECTIVE: To test the hypothesis that sleep disorder diagnosis would be associated with increased risk of preterm birth and to examine risk by gestational age, preterm birth type, and specific sleep disorder (insomnia, sleep apnea, movement disorder, and other). METHODS: In this observational study, participants were from a cohort of nearly 3 million women in California between 2007 and 2012. Inclusion criteria were women with singleton neonates liveborn between 20 and 44 weeks of gestation without chromosomal abnormalities or major structural birth defects linked to a hospital discharge database maintained by the California Office of Statewide Health Planning and Development and without mental illness during pregnancy...
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28739361/gender-affects-long-term-neurological%C3%A2-outcome-of-neonates
#7
Amir Freud, Eyal Sheiner, Tamar Wainstock, Daniella Landau, Asnat Walfisch
OBJECTIVE: We evaluated the possible association between fetal gender and long-term pediatric neurological morbidity. METHODS: We performed a population-based retrospective cohort analysis comparing the risk of long-term neurological morbidity (up to age 18 years) of children born during the years 1991 to 2013 according to their gender. Neurological morbidity evaluated included hospitalizations in childhood involving pervasive developmental disorder, obstructive sleep apnea, cerebral palsy, epilepsy, and infantile spasms and disorders of eating as recorded in the hospital files...
September 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28735925/upper-airway-flow-limitation-and-transcutaneous-carbon-dioxide-during-sleep-in-normal-pregnancy
#8
Ville Rimpilä, Riina Jernman, Katariina Lassila, Jukka Uotila, Heini Huhtala, Johanna Mäenpää, Olli Polo
OBJECTIVE: Sleep during pregnancy involves a physiological challenge to provide sufficient gas exchange to the fetus. Enhanced ventilatory responses to hypercapnia and hypoxia may protect from deficient gas exchange, but sleep-disordered breathing (SDB) may predispose to adverse events. The aim of this study was to analyze sleep and breathing in healthy pregnant women compared to non-pregnant controls, with a focus on CO2 changes and upper-airway flow limitation. METHODS: Healthy women in the third trimester and healthy non-pregnant women with normal body mass index (BMI) were recruited for polysomnography...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28692233/-sleep-apnea-in-pregnancy
#9
Wawrzyniec Rieder, Raphaël Heinzer, David Baud
Snoring, chronic rhinitis and fragmentation of sleep are common symptoms in pregnancy, especially in the third trimester. The prevalence of obstructive sleep apnea is also increased in pregnant women and can be associated with pregnancy induced hypertension, preeclampsia and diabetes mellitus. The fetus is as well exposed to a higher risk of prematurity and intra-uterine growth restriction. Given the lack of adequate screening tool, the diagnosis of obstructive sleep apnea is a challenge for the physician and a high degree of clinical suspicion is necessary in order to identify the patients at risk and propose an appropriate management...
October 26, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28449892/medical-comorbidity-in-narcolepsy-findings-from-the-burden-of-narcolepsy-disease-bond-study
#10
J Black, N L Reaven, S E Funk, K McGaughey, M M Ohayon, C Guilleminault, C Ruoff
OBJECTIVE/BACKGROUND: The objective of this study was to evaluate medical comorbidity patterns in patients with a narcolepsy diagnosis in the United States. PATIENTS/METHODS: This was a retrospective medical claims data analysis. Truven Health Analytics MarketScan® Research Databases were accessed to identify individuals ≥18 years of age with ≥1 diagnosis code for narcolepsy (International Classification of Diseases (ICD)-9, 347.0, 347.00, 347.01, 347.1, 347...
May 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28306346/risk-factors-for-central-serous-chorioretinopathy-multivariate-approach-in-a-case-control-study
#11
Irini Chatziralli, Stamatina A Kabanarou, Efstratios Parikakis, Alexandros Chatzirallis, Tina Xirou, Panagiotis Mitropoulos
PURPOSE: The purpose of this prospective study was to investigate the potential risk factors associated independently with central serous retinopathy (CSR) in a Greek population, using multivariate approach. MATERIALS AND METHODS: Participants in the study were 183 consecutive patients diagnosed with CSR and 183 controls, matched for age. All participants underwent complete ophthalmological examination and information regarding their sociodemographic, clinical, medical and ophthalmological history were recorded, so as to assess potential risk factors for CSR...
March 17, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28236270/oxidative-and-carbonyl-stress-in-pregnant-women-with-obstructive-sleep-apnea
#12
Nazia Khan, Geralyn Lambert-Messerlian, Joao Filipe Monteiro, Julius Hodosy, Ľubomíra Tóthová, Peter Celec, Elizabeth Eklund, Patrizia Curran, Ghada Bourjeily
PURPOSE: Pregnant women are particularly susceptible to sleep-disordered breathing. Obstructive sleep apnea (OSA) in pregnancy is associated with poor pregnancy and fetal outcomes. Oxidative stress caused by intermittent hypoxemia and reoxygenation may impact pregnancy health. We hypothesize that pregnant women with OSA have a pronounced oxidative stress profile. METHODS: A case-control study was performed to study oxidative stress markers in the serum of pregnant women with or without OSA...
February 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28134938/obstructive-sleep-apnea-and-perinatal-risk
#13
REVIEW
Margarita Reyes-Zúñiga, Luis Torre-Bouscoulet
Obstructive sleep apnea is characterized by total or partial interruptions of airflow during sleep, despite ongoing efforts to breathe. These pauses result from repeated upper airway obstructions that generate a systemic inflammatory condition with consequences for the endothelial function that increase the risk of cardiometabolic events. The prevalence of obstructive sleep apnea during pregnancy is greater than that observed in the general population and increases in the third trimester. Although limited, the information currently available supports the notion that obstructive sleep apnea is an independent, and potentially modifiable, risk factor for maternal and perinatal morbidity and mortality...
November 2016: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28121644/peripartum-management-of-obstructive-sleep-apnea
#14
Jessica M Booth, Ashley M Tonidandel
The prevalence of obstructive sleep apnea is unknown during pregnancy, but the syndrome is likely underdiagnosed and rising in frequency along with the obesity epidemic. Obstructive sleep apnea is associated with adverse outcomes, including hypertensive disorders of pregnancy, gestational diabetes, preterm, and cesarean delivery. Obese pregnant women should be screened and referred to a sleep medicine specialist for evaluation. Continuous positive airway pressure is the treatment of choice with demonstrated safety and compliance in pregnancy...
June 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28103130/serum-progesterone-levels-in-pregnant-women-with-obstructive-sleep-apnea-a-case-control-study
#15
Jennifer Lee, Elizabeth E Eklund, Geralyn Lambert-Messerlian, Glenn E Palomaki, Kristen Butterfield, Patrizia Curran, Ghada Bourjeily
BACKGROUND: Pregnancy is a risk factor for sleep disordered breathing, including obstructive sleep apnea (OSA). Progesterone, one of the key hormones in pregnancy, a known respiratory drive stimulant, increases ventilation and may protect against OSA. We aimed to examine the relationship between circulating progesterone and OSA, after accounting for body weight and gestational age. METHODS: A case control study was conducted of pregnant women with OSA and those at low risk for the disorder...
March 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28090638/late-gestational-intermittent-hypoxia-induces-metabolic-and-epigenetic-changes-in-male-adult-offspring-mice
#16
Abdelnaby Khalyfa, Rene Cortese, Zhuanhong Qiao, Honggang Ye, Riyue Bao, Jorge Andrade, David Gozal
KEY POINTS: Late gestation during pregnancy has been associated with a relatively high prevalence of obstructive sleep apnoea (OSA). Intermittent hypoxia, a hallmark of OSA, could impose significant long-term effects on somatic growth, energy homeostasis and metabolic function in offspring. Here we show that late gestation intermittent hypoxia induces metabolic dysfunction as reflected by increased body weight and adiposity index in adult male offspring that is paralleled by epigenomic alterations and inflammation in visceral white adipose tissue...
April 15, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28040612/association-of-obstructive-sleep-apnea-with-adverse-pregnancy-related-outcomes-in-military-hospitals
#17
Dennis L Spence, Rhonda C Allen, Monica A Lutgendorf, Virginia R Gary, John D Richard, Sara C Gonzalez
BACKGROUND: Obstructive sleep apnea (OSA) is associated with significant morbidity and mortality in non-obstetrical and obstetrical patients. OBJECTIVES: To estimate the prevalence of OSA and its relationship with pregnancy-related complications in a general obstetric population of Department of Defense beneficiaries receiving direct-care at military treatment facilities. STUDY DESIGN: A retrospective cohort study of all women (N=305,001) who gave birth at a military treatment facility from 2008 to 2014...
March 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28007402/performance-of-screening-questionnaires-for-obstructive-sleep-apnea-during-pregnancy-a-systematic-review-and-meta-analysis
#18
REVIEW
Visasiri Tantrakul, Pawin Numthavaj, Christian Guilleminault, Mark McEvoy, Panyu Panburana, Win Khaing, John Attia, Ammarin Thakkinstian
This review aims to evaluate the performance of obstructive sleep apnea (OSA) screening questionnaires during pregnancy. A systematic review and meta-analysis was performed using MEDLINE Scopus, CINAHL, and the Cochrane library. A bivariate meta-analysis was applied for pooling of diagnostic parameters. Six of the total 4719 articles met the inclusion criteria. The Berlin questionnaire (BQ, N = 604) and Epworth sleepiness scale (ESS, N = 420) were the most frequently used screening tools during pregnancy...
November 15, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/27974870/hemodynamic-response-to-upper-airway-obstruction-in-hypertensive-and-normotensive-pregnant-women
#19
John Reid, Riley A Glew, Joe Mink, John Gjevre, Mark Fenton, Robert Skomro, Femi Olatunbosun
Background. Mild obstructive sleep apnea is common in pregnancy and may have an exacerbating role in gestational hypertension, although currently the interaction between these two diseases is uncertain. Methods. We analyzed 43 pregnant subjects, 28 with gestational hypertension (GH) and 15 with normal healthy pregnancy, by level I polysomnography. Additionally, diastolic and systolic blood pressure changes in response to obstructive respiratory events were measured by noninvasive beat-by-beat monitoring. We also assessed a subgroup (n = 27) of women with respiratory disturbance indexes <5, for blood pressure responses to very subtle obstructive respiratory disturbances ("airflow reductions")...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/27926645/association-between-sleep-disordered-breathing-and-hypertensive-disorders-of-pregnancy-and-gestational-diabetes-mellitus
#20
MULTICENTER STUDY
Francesca L Facco, Corette B Parker, Uma M Reddy, Robert M Silver, Matthew A Koch, Judette M Louis, Robert C Basner, Judith H Chung, Chia-Ling Nhan-Chang, Grace W Pien, Susan Redline, William A Grobman, Deborah A Wing, Hyagriv N Simhan, David M Haas, Brian M Mercer, Samuel Parry, Daniel Mobley, Shannon Hunter, George R Saade, Frank P Schubert, Phyllis C Zee
OBJECTIVE: To estimate whether sleep-disordered breathing during pregnancy is a risk factor for the development of hypertensive disorders of pregnancy and gestational diabetes mellitus (GDM). METHODS: In this prospective cohort study, nulliparous women underwent in-home sleep-disordered breathing assessments in early (6-15 weeks of gestation) and midpregnancy (22-31 weeks of gestation). Participants and health care providers were blinded to the sleep test results...
January 2017: Obstetrics and Gynecology
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