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I R Costa, R S Mascarenhas, J F Corrêa, F R B Oliveira, S G Fernandes, F O Souza, G M Dos Reis, A de P R Júnior, D A Rodrigues, J V M Martins, K S F E Silva, K K V O Moura
The aim of this study was to determine the prevalence of polymorphisms in the glutathione S-transferase genes GSTM1 and GSTT1 in patients with lens opacity (cataract). Peripheral blood samples were obtained from male and female patients (N = 23) with cataract. The GSTM1 and GSTT1 polymorphic regions were amplified by polymerase chain reaction, and the amplification products were electrophoresed on a 2% agarose gel. The obtained bands were by staining with ethidium bromide. The results were compared by a chi-square test using the BioEstat software (v...
August 26, 2016: Genetics and Molecular Research: GMR
Paula Maia, Paulo Souza, Hildson Dornelas Angelo, Igor Santos, Danyelly Martins, Jose Lima Filho, Maria Mascena Maia
BACKGROUND: H19 is a strong candidate gene for influencing birth weight variation and is exclusively imprinted maternally. In an attempt to understand the relationship of this gene polymorphism with low birth weight children, we investigated association of H19/RsaI polymorphism with low birth weight and normal birth weight in children and their mothers. OBJECTIVES: The aim of our study was to establish the association between H19 gene polymorphism and LW in children born in Pernambuco, state of Brazil...
April 2015: Iranian Journal of Pediatrics
Matheus Melo Pithon, Daniel Santos Fonseca Figueiredo, Dauro Douglas Oliveira, Raildo da Silva Coqueiro
BACKGROUND: The aim of this clinical investigation was to compare the level of discomfort reported by patients during the removal of orthodontic metallic brackets performed with four different debonding instruments. METHODS: The sample examined in this split-mouth study comprised a total of 70 patients (840 teeth). Four different methods of bracket removal were used: lift-off debonding instrument (LODI), straight cutter plier (SC), how plier (HP), and bracket removal plier (BRP)...
2015: Progress in Orthodontics
Any Carolina C G Vasconcelos, Edmilson de Souza R Neto, Giovanny R Pinto, France Keiko N Yoshioka, Fábio José N Motta, Daniel Fernando P Vasconcelos, Renata Canalle
BACKGROUND: Alcohol dependence (AD) is a complex psychiatric disorder, affecting 5.4% of the general population lifetime, characterized by excessive alcohol consumption influenced by environmental risk factors and genetic factors. Genetic alterations in dopaminergic system are involved in the treatment and etiology of AD. The aim of this search was to test the association of the SLC6A3 40 bp-VNTR and DRD2/ANKK1 Taq1A single nucleotide polymorphism (SNP), a transporter and receptor of the dopaminergic system, with AD through a study in a population of northeastern Brazil...
February 2015: Alcoholism, Clinical and Experimental Research
Felipe Ferreira S Oliveira, Eliane Aparecida Suchara
OBJECTIVE: To study the epidemiology of exogenous intoxications in children and adolescents of Barra Garças, Mato Grosso, from January 2008 to September 2013. METHOD: This was a cross-sectional, retrospective, and descriptive epidemiological study. Data were collected from the Disease Notification System (Sistema de Informação de Agravos de Notificação [SINAN]) of the municipality, processed using Microsoft Excel, and evaluated through BIOESTAT statistical software...
December 2014: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Ana Maria Almeida Souza, Thiago Pimentel Muniz, Rafael Maciel Brito
OBJECTIVE: To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. METHODS: Data were collected from patient records and analyzed using BioEstat software (version 5.0). Student's t-test, Analysis of Variance (ANOVA), Wilcoxon test and Kruskal-Wallis test were used for statistical analysis. Hepatomegaly and splenomegaly were analyzed using the Kappa test. RESULTS: There was a significant increase in hemoglobin levels (p-value <0...
September 2014: Revista Brasileira de Hematologia e Hemoterapia
Rubistenia Miranda Soares de Araújo, Cynthia Farias Vieira de Melo, Fidelis Manes Neto, Juarez Nóbrega da Silva, Leonardo Ferreira Soares, Marilia de Arruda Cardoso Smith, Edilson Carvalho Sousa, Rommel Mario Rodríguez Burbano, Arnaldo Correia de Medeiros, Eleonidas Moura Lima
Cancer is a multifactorial disease with a high mortality rate in Brazil and worldwide. Gastric cancer (GC) is considered the fourth type of malignancy more frequent in the population worldwide and the second leading cause of death. This work aimed to evaluate single nucleotide polymorphisms (SNPs) of IFNGR1, GSTT1, and GSTP1 genes samples in gastric cancer. We analyzed 60 samples of gastric cancer, 26 diffuse and 34 intestinal types, totaling 120 alleles for each SNP. The results were obtained by PCR and allele-specific PCR...
May 2014: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
Adenauer Marinho de Oliveira Góes Junior, Simone de Campos Vieira Abib, Maria Teresa de Seixas Alves, Paulo Sérgio Venerando da Silva Ferreira, Mariseth Carvalho de Andrade
BACKGROUND: To evaluate vascular flow through temporary vascular shunts inserted into peripheral arteries and veins and the repercussion, on the arterial perfusion, of venous ligation and venous shunt insertion in an experimental model for damage control. METHODS: Experimental study in pigs. Animals were distributed in 5 groups: group 1, right external iliac artery (EIA) shunting and right external iliac vein (EIV) ligation; group 2, right EIA shunting and right EIV shunting; group 3, right EIV ligation; group 4, right EIV shunting; group 5, no vascular shunting and no venous ligation...
April 2014: Annals of Vascular Surgery
André Luiz Peixoto Figueiredo, Liliane Lins, Ana Carolina Cattony, Antônio Fernando Pereira Falcão
OBJECTIVE: To conduct a systematic review and meta-analysis of the effectiveness of Laser Therapy in the prevention of oral mucositis (OM) in patients undergoing oncotherapy. METHODS: To this systematic review and meta-analysis a search was performed in MEDLINE, LILACS and Cochrane using the keywords "laser therapy" and "Oral mucostitis." The case-control studies included were submitted to odds ratio (OR) analysis, which the cut-off point for statistic calculation was OM grade > 3...
September 2013: Revista da Associação Médica Brasileira
Karla Barros Bezerra, Diego Salvador Muniz da Silva, Maria Bethânia da Costa Chein, Patricia Rodrigues Ferreira, Jessika Kelly Passos Maranhão, Nayana Leite Ribeiro, Elba Gomide Mochel
The study sought to evaluate the quality of life of women treated surgically for breast cancer at the State Oncology Hospital of Reference in São Luís in the State of Maranhão. The quality of life was assessed by the Functional Assessment of Cancer Therapy-Breast (FACT-B). The variables were expressed as mean and standard deviation, and statistical analysis consisted of the ANOVA or Kruskal Wallis test and the Student t or Mann-Whitney test. The level of significance was α < 5%. For statistical tests Stata 9...
July 2013: Ciência & Saúde Coletiva
Lívia de Almeida Barros Bertulucci, Flavia Maria Barros Guimarães Pereira, Ana Emília Figueiredo de Oliveira, Luciane Maria Oliveira Brito, Fernanda Ferreira Lopes
PURPOSE: To investigate the relationship between periodontitis and osteoporosis, using a case-control study about periodontal status of postmenopausal women. METHODS: A total of 99 postmenopausal women were divided into three groups: normal bone (Gn, n=45), osteopenia (Gpenia, n=31) and osteoporosis (Gporosis, n=23). The categorization of bone mass was measured by dual energy absorptiometry with X-rays in the lumbar spine (L2 - L4), by assessing bone mineral density...
December 2012: Revista Brasileira de Ginecologia e Obstetrícia
Victor Diniz de Pochat, Nivaldo Alonso, Emilie B Ribeiro, Emanuelle A da Rocha, Edinho G Tenório, Jose Valber Lima Meneses
BACKGROUND: Upper lateral cartilage manipulation is often associated with compromise of the middle-third vault. Although the anatomical details of the upper lateral cartilages are of great importance for the maintenance or even the creation of an aesthetically pleasing dorsum with proper respiratory function, the literature includes few studies related to these themes. Thus, this study aimed to evaluate the total length of the upper lateral cartilages and their extension under the nasal bones and caudally, and examine the anatomical variations of the upper lateral cartilages and their implications in rhinoplasty...
April 2012: Aesthetic Plastic Surgery
Éldi Vendrame Parise, Gessi Carvalho de Araújo, José Gerley Diaz Castro, Fernando Pedroso Berdarrain
This study describes the epidemiological profile of malaria in the State of Tocantins, in the period 2003-2008, investigates the association between the frequency of malaria and population growth, classifies the cases by 'autochthonous' and 'imported', reports the indices of the disease and analyses the distribution of the cases by Plasmodium species, age and gender. The retrospective study was based on secondary data, stored in SIVEP-malaria and analyzed using the software Epi-Info 3.5.1. and Bioestat 5.0...
May 2011: Revista do Instituto de Medicina Tropical de São Paulo
Eldi Vendrame Parise, Gessi Carvalho de Araújo, Renato Torres Pinheiro
INTRODUCTION: In Tocantins, the behavior of malaria differs between microregions, with predominance of imported cases. This study describes a spatial analysis on malaria in the state covering 2003 to 2008, which sought to identify the incidence of autochthonous and imported cases, and the origin of the latter, in the microregions. METHODS: This was a retrospective study using secondary data. The data source was the epidemiological surveillance information system for malaria (SIVEP-Malária), and the data were analyzed using the Epi Info version 3...
January 2011: Revista da Sociedade Brasileira de Medicina Tropical
Marina Beloti Ferreira, Suely Myiagi, Carlos Goes Nogales, Marcia Sampaio Campos, José Luiz Lage-Marques
OBJECTIVE: New drugs have to be assessed in endodontic therapy due to the presence of microorganisms resistant to therapeutic procedures. Thus, this study evaluated the time- and concentration-dependent cytotoxicity of different antibiotics used in endodontic therapy. MATERIAL AND METHODS: Human gingival fibroblasts were treated and divided into the following experimental groups: Group I - control; Group II - ciprofloxacin hydrochloride; Group III - clyndamicin hydrochloride; and Group IV - metronidazole...
May 2010: Journal of Applied Oral Science: Revista FOB
Giovanna Ribeiro Souto, Marcelo Vidigal Caliari, Carolina Emmanuelle Camargos Lins, Maria Cássia Ferreira de Aguiar, Mauro Henrique Nogueira Guimarães de Abreu, Ricardo Alves Mesquita
BACKGROUND: The most important risk factor linked to the development of oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC) is tobacco use. Tobacco contains carcinogens that influence the DNA repair, cell cycle control and may produce chromosomal aberrations. The loss or acquisition of one or more chromosomes is defined as aneuploidy. METHODS: Aneuploidy was determined by means of the DNA-content included in cells obtained by exfoliative cytology and Feulgen's staining...
September 2010: Journal of Oral Pathology & Medicine
A S M Cesar, A C P Silveira, P F A Freitas, E C Guimarães, D F A Batista, L C Torido, F V Meirelles, R C Antunes
We compared carcass and meat quality of pigs from the same sire line and two different dam lines, one that included Chinese breeds and one that did not. Line A consisted of 1/4 Landrace, 1/2 Large White, 1/8 Chinese breeds (Meishan, Fengjing, Jiaxing), and 1/8 Large White, Duroc and Pietrain, and line B consisted of 1/2 Large White and 1/2 Pietrain. The animals (N = 144) were slaughtered at a live weight of 108 kg. Backfat thickness, percentage of lean meat, pH 24 h after slaughter, meat color, percentage of drip loss, and percentage of intramuscular fat were measured and compared using analysis of variance in a completely randomized design; the BioEstat 5...
2010: Genetics and Molecular Research: GMR
Joel Saraiva Ferreira, Ricardo Dutra Aydos
There has been an increase in chronic diseases affecting the population not only in the world but also in Brazil. Hypertension and obesity fit this context, including among early age individuals. This paper aims at investigating the prevalence of hypertension among obese children and adolescents, checking its manifestation in compliance with gender and age. The study involved 129 obese individuals, ages ranging from 7 to 14 years, both sexes. The evaluation consisted of anthropometric measures and blood pressure measurements...
January 2010: Ciência & Saúde Coletiva
Lucio Mitsuo Kurita, Alynne Vieira Menezes, Marcia Spinelli Casanova, Francisco Haiter-Neto
OBJECTIVE: The purpose of this investigation was to evaluate the applicability of the methods proposed by Nolla and by Nicodemo and colleagues for assessing dental age and its correlation to chronological age. METHODS: Panoramic radiographs of 360 patients from the city of Fortaleza (CE, Brazil) aged 7-15 years were used to assess the associations between dental and chronological age. Data were submitted to statistical analysis using the BioEstat 2.0 (2000) software...
April 2007: Journal of Applied Oral Science: Revista FOB
Sérgio Henrique Sampaio Meirelles, Cristina Rodrigues Mathias, Renata Rianelli Bloise, Neire Sandra Flores Stohler, Simone Duarte Liporaci, Ana Carolina Frota, Camila Cassiano Simões
PURPOSE: To evaluate the change in optic disc cupping after surgical procedure for congenital glaucoma and assess the factors that may intervene on this process. METHODS: Prospective study involving 45 eyes of 36 patients with childhood glaucoma, who underwent surgical treatment at the Hospital Municipal da Piedade, Rio de Janeiro, Brazil, between January 1998 and December 2005. The study included patients <5 years old with intraocular pressure (IOP) <19 mm Hg for at least 6 months after surgery...
September 2008: Journal of Glaucoma
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