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https://www.readbyqxmd.com/read/28221348/self-assembly-of-nanoparticles-into-biomimetic-capsid-like-nanoshells
#1
Ming Yang, Henry Chan, Gongpu Zhao, Joong Hwan Bahng, Peijun Zhang, Petr Král, Nicholas A Kotov
Nanoscale compartments are one of the foundational elements of living systems. Capsids, carboxysomes, exosomes, vacuoles and other nanoshells easily self-assemble from biomolecules such as lipids or proteins, but not from inorganic nanomaterials because of difficulties with the replication of spherical tiling. Here we show that stabilizer-free polydispersed inorganic nanoparticles (NPs) can spontaneously organize into porous nanoshells. The association of water-soluble CdS NPs into self-limited spherical capsules is the result of scale-modified electrostatic, dispersion and other colloidal forces...
March 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28209031/carbon-nanomaterial-formation-on-fresh-reduced-iron-by-converted-natural-gas
#2
A Nebesnyi, V Kotov, A Sviatenko, D Filonenko, A Khovavko, B Bondarenko
The mechanism of carbon nanomaterial formation at moderate temperatures while processing fresh-reduced iron by products of air conversion of natural gas is considered. It is shown that under given conditions, the size and the shape of the resulting carbon are dependent on the temperature and the size of microscopic iron grains formed during reduction. These iron grains are the catalyzer of the reaction of carbon monoxide disproportionation. It is concluded that the formation of a nucleus of the new carbon phase occurs at the contact boundaries of neighboring grains of newly reduced iron with the subsequent formation in these places of ring-shaped carbon cuffs...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28199099/nanoscience-and-nanotechnology-cross-borders
#3
Ali Khademhosseini, Warren W C Chan, Manish Chhowalla, Sharon C Glotzer, Yury Gogotsi, Jason H Hafner, Paula T Hammond, Mark C Hersam, Ali Javey, Cherie R Kagan, Nicholas A Kotov, Shuit-Tong Lee, Yan Li, Helmuth Möhwald, Paul A Mulvaney, Andre E Nel, Wolfgang J Parak, Reginald M Penner, Andrey L Rogach, Raymond E Schaak, Molly M Stevens, Andrew T S Wee, Jeffrey Brinker, Xiaoyuan Chen, Lifeng Chi, Michael Crommie, Cees Dekker, Omid Farokhzad, Christoph Gerber, David S Ginger, Darrell J Irvine, Laura L Kiessling, Kostas Kostarelos, Christy Landes, Takhee Lee, Graham J Leggett, Xing-Jie Liang, Luis Liz-Marzán, Jill Millstone, Teri W Odom, Aydogan Ozcan, Maurizio Prato, C N R Rao, Michael J Sailor, Emily Weiss, Paul S Weiss
No abstract text is available yet for this article.
February 15, 2017: ACS Nano
https://www.readbyqxmd.com/read/28190795/progress-in-understanding-the-molecular-functions-of-ddx3y-dby-in-male-germ-cell-development-and-maintenance
#4
Alexei A Kotov, Oxana M Olenkina, Baira K Godneeva, Vladimir E Adashev, Ludmila V Olenina
Human DDX3 paralogs are housed on the X chromosome (DDX3X) as well as in the non- recombining region Yq11 of the Y-chromosome (DDX3Y or DBY). A gene encoding RNA helicase DDX3Y is located in the AZoospermia Factor a (AZFa) region of the Y-chromosome and expressed only in male germ cells. Deletions encompassing the DDX3Y gene lead to azoospermia and cause Sertoli Cell-Only Syndrome (SCOS) in humans. SCOS is characterized by a complete germ cell lack with preservation of somatic Sertoli cells. This review summarizes current advances in the study of DDX3Y functions in maintenance and development of early male germ cells...
February 12, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/28099776/understanding-the-connection-between-posttraumatic-stress-symptoms-and-respiratory-problems-contributions-of-anxiety-sensitivity
#5
Brittain L Mahaffey, Adam Gonzalez, Samantha G Farris, Michael J Zvolensky, Evelyn J Bromet, Benjamin J Luft, Roman Kotov
Respiratory problems and posttraumatic stress disorder (PTSD) are the signature health consequences associated with the September 11, 2001 (9/11), World Trade Center disaster and frequently co-occur. The reasons for this comorbidity, however, remain unknown. Anxiety sensitivity is a transdiagnostic trait that is associated with both PTSD and respiratory symptoms. The present study explored whether anxiety sensitivity could explain the experience of respiratory symptoms in trauma-exposed smokers with PTSD symptoms...
February 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28075573/functional-graphene-nanomaterials-based-architectures-biointeractions-fabrications-and-emerging-biological-applications
#6
Chong Cheng, Shuang Li, Arne Thomas, Nicholas A Kotov, Rainer Haag
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely unique physical and chemical properties and physiological ability to interfere and/or interact with bioorganisms; as a result, FGNs present manifold possibilities for diverse biological applications. Beyond their use in drug/gene delivery, phototherapy, and bioimaging, recent studies have revealed that FGNs can significantly promote interfacial biointeractions, in particular, with proteins, mammalian cells/stem cells, and microbials...
January 11, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28024354/nanoscience-and-nanotechnology-impacting-diverse-fields-of-science-engineering-and-medicine
#7
Warren W C Chan, Manish Chhowalla, Sharon Glotzer, Yury Gogotsi, Jason H Hafner, Paula T Hammond, Mark C Hersam, Ali Javey, Cherie R Kagan, Ali Khademhosseini, Nicholas A Kotov, Shuit-Tong Lee, Yan Li, Helmuth Möhwald, Paul A Mulvaney, Andre E Nel, Peter J Nordlander, Wolfgang J Parak, Reginald M Penner, Andrey L Rogach, Raymond E Schaak, Molly M Stevens, Andrew T S Wee, C Grant Willson, Laura E Fernandez, Paul S Weiss
No abstract text is available yet for this article.
December 27, 2016: ACS Nano
https://www.readbyqxmd.com/read/28013272/trauma-focused-smoking-cessation-for-smokers-exposed-to-the-world-trade-center-disaster-a-randomized-clinical-trial
#8
Adam Gonzalez, Fred Friedberg, Xiaotong Li, Michael J Zvolensky, Evelyn J Bromet, Brittain L Mahaffey, Anka A Vujanovic, Benjamin J Luft, Roman Kotov
INTRODUCTION: The main objective was to evaluate the efficacy of an 8-session, group-based comprehensive smoking cessation and trauma management (CSC-T) treatment among daily smokers (≥ 5 cigarettes/day) exposed to the WTC disaster with elevated WTC-related PTSD symptoms. METHODS: Participants (N=90) were randomly assigned to CSC-T (N=44; 63.6% White; 27.3% female; mean age = 51.32±7.87) or comprehensive smoking cessation (CSC) alone (N=46; 71.7% White; 28.3% female; mean age=48...
December 24, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28005053/-leber-s-hereditary-optic-neuropathy-and-epilepsy-a-case-report
#9
A S Kotov, E V Gushchina, Yu V Matyuk, M N Borisova, M V Panteleeva, A V Shatalin
A clinical case of a young man with rapid bilateral visual impairment developed 2 months after the onset of generalized convulsive seizures is presented. The replacement of valproate to levetiracetam led to the remission of seizures, but the prognosis for vision remains poor, particularly given the pessimistic results of optical coherence tomography (OCT).
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27995812/social-support-buffers-the-effect-of-interpersonal-life-stress-on-suicidal-ideation-and-self-injury-during-adolescence
#10
D M Mackin, G Perlman, J Davila, R Kotov, D N Klein
BACKGROUND: The effect of life stress on suicidal symptoms during adolescence is well documented. Stressful life events can trigger suicidality, but most adolescents are resilient and it is unclear which factors protect against the deleterious impact of stress. Social support is thought to be one such factor. Therefore, we investigated the buffering effect of specific sources of social support (parental and peer) on life stress (interpersonal and non-interpersonal) in predicting suicidal symptoms during adolescence...
December 20, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27992559/phylogeography-of-the-chydorus-sphaericus-group-cladocera-chydoridae-in-the-northern-palearctic
#11
Alexey A Kotov, Dmitry P Karabanov, Eugeniya I Bekker, Tatiana V Neretina, Derek J Taylor
The biodiversity and the biogeography are still poorly understood for freshwater invertebrates. The crustacean Chydorus sphaericus-brevilabris complex (Cladocera: Chydoridae) is composed of species that are important components of Holarctic freshwater food webs. Recent morphological and genetic study of the complex has indicated a substantial species diversity in the northern hemisphere. However, we know little of the geographic boundaries of these novel lineages. Moreover, a large section of the Palearctic remains unexamined at the genetic level...
2016: PloS One
https://www.readbyqxmd.com/read/27978770/the-20-year-longitudinal-trajectories-of-social-functioning-in-individuals-with-psychotic-disorders
#12
Eva Velthorst, Anne-Kathrin J Fett, Avraham Reichenberg, Greg Perlman, Jim van Os, Evelyn J Bromet, Roman Kotov
OBJECTIVE: Social impairment is a long-recognized core feature of schizophrenia and is common in other psychotic disorders. Still, to date the long-term trajectories of social impairment in psychotic disorders have rarely been studied systematically. METHODS: Data came from the Suffolk County Mental Health Project, a 20-year prospective study of first-admission patients with psychotic disorders. A never-psychotic comparison group was also assessed. Latent class growth analysis was applied to longitudinal data on social functioning from 485 respondents with schizophrenia spectrum disorders and psychotic mood disorders, and associations of the empirically derived trajectories with premorbid social adjustment, diagnosis, and 20-year outcomes were examined...
December 16, 2016: American Journal of Psychiatry
https://www.readbyqxmd.com/read/27976812/hurricane-sandy-exposure-alters-the-development-of-neural-reactivity-to-negative-stimuli-in-children
#13
Ellen M Kessel, Brady D Nelson, Autumn Kujawa, Greg Hajcak, Roman Kotov, Evelyn J Bromet, Gabrielle A Carlson, Daniel N Klein
This study examined whether exposure to Hurricane Sandy-related stressors altered children's brain response to emotional information. An average of 8 months (Mage  = 9.19) before and 9 months after (Mage  = 10.95) Hurricane Sandy, 77 children experiencing high (n = 37) and low (n = 40) levels of hurricane-related stress exposure completed a task in which the late positive potential, a neural index of emotional reactivity, was measured in response to pleasant and unpleasant, compared to neutral, images...
December 15, 2016: Child Development
https://www.readbyqxmd.com/read/27828501/strong-coupling-of-localized-surface-plasmons-and-ensembles-of-dye-molecules
#14
V N Peters, T U Tumkur, Jing Ma, Nicholas A Kotov, M A Noginov
We have studied strong exciton-plasmon coupling in the films of Ag nanoislands as well as in the layer-by-layer (LBL) deposited films of Au nanoparticles (NPs) coated with highly concentrated rhodamine 6G (R6G) dye. Their absorbance and the reflectance spectra featured the peaks or dips, which were not characteristic of dye or NPs/nanoislands taken separately. The positions of the spectral maxima (or minima) in the dye-doped films, plotted against those in pristine Ag nanoislands films, resulted in the dispersion curves comprised of three branches...
October 31, 2016: Optics Express
https://www.readbyqxmd.com/read/27819471/validating-dimensions-of-psychosis-symptomatology-neural-correlates-and-20-year-outcomes
#15
Roman Kotov, Dan Foti, Kaiqiao Li, Evelyn J Bromet, Greg Hajcak, Camilo J Ruggero
Heterogeneity of psychosis presents significant challenges for classification. Between 2 and 12 symptom dimensions have been proposed, and consensus is lacking. The present study sought to identify uniquely informative models by comparing the validity of these alternatives. An epidemiologic cohort of 628 first-admission inpatients with psychosis was interviewed 6 times over 2 decades and completed an electrophysiological assessment of error processing at year 20. We first analyzed a comprehensive set of 49 symptoms rated by interviewers at baseline, progressively extracting from 1 to 12 factors...
November 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27814456/the-role-of-parental-psychopathology-and-personality-in-adolescent-non-suicidal-self-injury
#16
Molly A Gromatsky, Monika A Waszczuk, Greg Perlman, Katie Lee Salis, Daniel N Klein, Roman Kotov
Adolescent non-suicidal self-injury (NSSI), a significant risk factor for suicidal behavior, is strongly associated with adolescent psychopathology and personality traits, particularly those characterized by poor self-regulation. Some parental psychopathology and personality traits have also been identified as risk factors for adolescent NSSI, but specific parental characteristics and mechanisms involved in this association have not been systematically examined. The current study comprehensively investigated the contribution of parental psychopathology and personality to adolescent NSSI using data from the baseline wave of the Adolescent Development of Emotion and Personality Traits (ADEPT) study of 550 adolescent girls (mean age = 14...
February 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27798171/polymicrobial-sepsis-diminishes-dendritic-cell-numbers-and-function-directly-contributing-to-impaired-primary-cd8-t-cell-responses-in-vivo
#17
Robert K Strother, Derek B Danahy, Dmitri I Kotov, Tamara A Kucaba, Zeb R Zacharias, Thomas S Griffith, Kevin L Legge, Vladimir P Badovinac
Patients surviving acute stages of sepsis often display impaired adaptive-immune responses. Using the cecal ligation and puncture model, we demonstrated that sepsis leads to substantial and long-lasting changes in the naive CD8 T cell repertoire, affecting the capacity of the host to respond to new infections. However, the identity of CD8 T cell-extrinsic factor(s) and mechanism(s) that contribute to impaired CD8 T cell responses after sepsis is unknown. Priming of naive CD8 T cells is critically dependent on the ability of dendritic cells (DCs) to provide Ag, costimulation, and inflammatory signal 3 cytokines; therefore, the sepsis-induced changes in the DC compartment might represent a contributing factor leading to diminished CD8 T cell immunity in septic hosts...
December 1, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27756045/etiologic-specificity-of-waking-cortisol-links-with-maternal-history-of-depression-and-anxiety-in-adolescent-girls
#18
Brandon L Goldstein, Greg Perlman, Roman Kotov, Joan E Broderick, Keke Liu, Camilo Ruggero, Daniel N Klein
BACKGROUND: Many previous studies have indicated that individuals who are depressed or at risk for depression are characterized by increased levels of morning cortisol and a greater cortisol awakening response (CAR). However, despite the high comorbidity between depressive and anxiety disorders, fewer studies have examined whether these diurnal cortisol abnormalities are also characteristic of anxiety or risk for anxiety. METHODS: In the present study we examined cortisol in a community sample of 476 female adolescents and related it to maternal history of depression and/or anxiety disorders...
January 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27735906/-the-neurological-manifestations-of-fabry-disease-a-review
#19
K V Firsov, A S Kotov
Fabry disease (Anderson-Fabry disease) is an X-linked recessive lysosomal storage disorder resulting from deficient activity of lysosomal hydrolase, alpha-galactosidase A (alpha-Gal A), which leads to progressive accumulation of globotriaosylceramide (Gb3) in various cells, predominantly endothelial and vascular smooth muscle cells, with clinical manifestations affecting major organs including the central nervous system. Manifestations of Fabry disease include progressive renal and cardiac insufficiency, neuropathic pain, stroke and cerebral disease, skin and gastrointestinal symptoms...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27723734/particle-self-assembly-superstructures-simplified
#20
Nicholas A Kotov
No abstract text is available yet for this article.
December 2016: Nature Nanotechnology
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