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https://www.readbyqxmd.com/read/29766970/fetal-meningocele-manqu%C3%A3
#1
M H Shabina Banu, Rajeswaran Rangasami, Indrani Suresh
No abstract text is available yet for this article.
May 2018: Neurology India
https://www.readbyqxmd.com/read/29528401/assessment-of-knowledge-attitudes-and-practices-towards-newborn-screening-for-congenital-hypothyroidism-before-and-after-a-health-education-intervention-in-pregnant-women-in-a-hospital-setting-in-pakistan
#2
Batha Tariq, Ayesha Ahmed, Atif Habib, Ali Turab, Noshad Ali, Sajid Bashir Soofi, Shanila Nooruddin, Rekha J Kumar, Amin Tariq, Fariha Shaheen, Shabina Ariff
Background: Most congenital hypothyroidism (CH) is not avertable; however, the adverse effects of CH are preventable with early detection and treatment. It is a common congenital endocrine disorder that affects 1 in 2000-4000 newborns globally. The true incidence in Pakistan is unknown. Data from hospital studies quote an incidence of 1 in 1600-2000. The aim of this study was to uncover existing knowledge of CH and screening for the condition and to assess the impact of health education on mothers' knowledge and attitudes towards having their newborns screened...
March 1, 2018: International Health
https://www.readbyqxmd.com/read/29470320/exchangeable-zinc-pool-size-at-birth-in-pakistani-small-for-gestational-age-and-appropriate-for-gestational-age-infants-do-not-differ-but-are-lower-than-in-us-infants
#3
Shabina Ariff, Nancy F Krebs, Jamie E Westcott, Michael Hambidge, Leland V Miller, Arjumand Rizvi, Sajid B Soofi, Zulfiqar A Bhutta
OBJECTIVES: Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not been examined. METHODS: In a community-based, observational, longitudinal study in a peri-urban settlement of Karachi, Pakistan, we compared the size of the exchangeable zinc pools (EZPs) in term SGA and AGA infants at birth and at 6 months of age, hypothesizing that the EZP would be lower in the SGA group...
March 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29319147/factors-associated-with-low-birthweight-in-term-pregnancies-a-matched-case-control-study-from-rural-pakistan
#4
Muhammad A Habib, Camille R Greenow, Shabina Ariff, Sajid Soofi, Abid Hussain, Qamar Junejo, Amjad Hussain, Fariha Shaheen, Kirsten I Black
Low birthweight (LBW) remains a significant public health problem in Pakistan and further understanding of factors associated with LBW is required. We conducted a hospital-based matched case control study to identify risk factors associated with LBW in a rural district of Pakistan. We found that illiteracy (AOR: 2.68; 95% CI: 1.59 - 4.38), nulliparity (AOR: 1.82; 95% CI: 1.26-2.44), having a previous miscarriage/abortion (AOR: 1.22; 95% CI: 1.06-2.35), having < 2 antenatal care (ANC) visits during last pregnancy (AOR: 2...
January 2, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29275342/prevalence-and-possible-factors-associated-with-anaemia-and-vitamin-b-12-and-folate-deficiencies-in-women-of-reproductive-age-in-pakistan-analysis-of-national-level-secondary-survey-data
#5
Sajid Soofi, Gul Nawaz Khan, Kamran Sadiq, Shabina Ariff, Atif Habib, Sumra Kureishy, Imtiaz Hussain, Muhammad Umer, Zamir Suhag, Arjumand Rizvi, Zulfiqar Bhutta
OBJECTIVE: To determine the prevalence and possible factors associated with anaemia, and vitamin B12 and folate deficiencies in women of reproductive age (WRA) in Pakistan. METHODS: A secondary analysis was conducted on data collected through the large-scale National Nutrition Survey in Pakistan in 2011. Anaemia was defined as haemoglobin levels <12 g/dL, vitamin B12 deficiency as serum vitamin B12 levels of <203 pg/mL (150 pmol/L) and folate deficiency as serum folate levels <4 ng/mL (10 nmol/L)...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29133249/immunomodulation-of-dual-specificity-phosphatase-4-during-visceral-leishmaniasis
#6
Shabina Parveen, Atish Roy Chowdhury, Junaid Jibran Jawed, Suchandra Bhattacharyya Majumdar, Bhaskar Saha, Subrata Majumdar
DUSP4, an inducible protein has a substrate specificity toward ERK1/2, a component of MAP kinase which is enhanced during Leishmania infection. The DUSP4-/- mice show increased susceptibility towards the infection caused by Toxoplasma gondii and Leishmania mexicana. These observations emphatically established the fact that unlike DUSP1, DUSP4 has host protective role. In our study, it has been Leishmania donovani, the causative agent of visceral leishmaniasis (VL) significantly reduced the expression of DUSP4 during infection...
February 2018: Microbes and Infection
https://www.readbyqxmd.com/read/29082019/antenatal-corticosteroids-for-women-at-risk-of-imminent-preterm-birth-in-low-resource-countries-the-case-for-equipoise-and-the-need-for-efficacy-trials
#7
REVIEW
Joshua P Vogel, Olufemi T Oladapo, Cynthia Pileggi-Castro, Ebunoluwa A Adejuyigbe, Fernando Althabe, Shabina Ariff, Adejumoke Idowu Ayede, Abdullah H Baqui, Anthony Costello, Davy M Chikamata, Caroline Crowther, Bukola Fawole, Luz Gibbons, Alan H Jobe, Monica Lulu Kapasa, John Kinuthia, Alka Kriplani, Oluwafemi Kuti, James Neilson, Janna Patterson, Gilda Piaggio, Rahat Qureshi, Zahida Qureshi, Mari Jeeva Sankar, Jeffrey S A Stringer, Marleen Temmerman, Khalid Yunis, Rajiv Bahl, A Metin Gülmezoglu
The scientific basis for antenatal corticosteroids (ACS) for women at risk of preterm birth has rapidly changed in recent years. Two landmark trials-the Antenatal Corticosteroid Trial and the Antenatal Late Preterm Steroids Trial-have challenged the long-held assumptions on the comparative health benefits and harms regarding the use of ACS for preterm birth across all levels of care and contexts, including resource-limited settings. Researchers, clinicians, programme managers, policymakers and donors working in low-income and middle-income countries now face challenging questions of whether, where and how ACS can be used to optimise outcomes for both women and preterm newborns...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29081267/delayed-versus-immediate-cord-clamping-in-preterm-infants
#8
RANDOMIZED CONTROLLED TRIAL
William Tarnow-Mordi, Jonathan Morris, Adrienne Kirby, Kristy Robledo, Lisa Askie, Rebecca Brown, Nicholas Evans, Sarah Finlayson, Michael Fogarty, Val Gebski, Alpana Ghadge, Wendy Hague, David Isaacs, Michelle Jeffery, Anthony Keech, Martin Kluckow, Himanshu Popat, Lucille Sebastian, Kjersti Aagaard, Michael Belfort, Mohan Pammi, Mohamed Abdel-Latif, Graham Reynolds, Shabina Ariff, Lumaan Sheikh, Yan Chen, Paul Colditz, Helen Liley, Margo Pritchard, Daniele de Luca, Koert de Waal, Peta Forder, Lelia Duley, Walid El-Naggar, Andrew Gill, John Newnham, Karen Simmer, Katie Groom, Philip Weston, Joanna Gullam, Harshad Patel, Guan Koh, Kei Lui, Neil Marlow, Scott Morris, Arvind Sehgal, Euan Wallace, Roger Soll, Leslie Young, David Sweet, Susan Walker, Andrew Watkins, Ian Wright, David Osborn, John Simes
BACKGROUND: The preferred timing of umbilical-cord clamping in preterm infants is unclear. METHODS: We randomly assigned fetuses from women who were expected to deliver before 30 weeks of gestation to either immediate clamping of the umbilical cord (≤10 seconds after delivery) or delayed clamping (≥60 seconds after delivery). The primary composite outcome was death or major morbidity (defined as severe brain injury on postnatal ultrasonography, severe retinopathy of prematurity, necrotizing enterocolitis, or late-onset sepsis) by 36 weeks of postmenstrual age...
December 21, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29040888/physical-capability-predicts-mortality-in-late-mid-life-as-well-as-in-old-age-findings-from-a-large-british-cohort-study
#9
Victoria L Keevil, Robert Luben, Shabina Hayat, Avan A Sayer, Nicholas J Wareham, Kay-Tee Khaw
INTRODUCTION: Low physical capability predicts mortality, perhaps by association with co-morbidity. However, few studies include participants <70years old with lower co-morbidity burdens compared to older adults. We examined relationships between usual walking speed (UWS), timed chair stands speed, grip strength, standing balance and all-cause mortality in 8477 participants aged 48-92years enrolled in the European Prospective Investigation of Cancer-Norfolk study. METHODS: Participants (55...
January 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29036009/exchangeable-zinc-pool-size-at-birth-in-pakistani-sga-and-aga-infants-do-not-differ-but-are-lower-than-in-us-infants
#10
Shabina Ariff, Nancy F Krebs, Jamie E Westcott, K Michael Hambidge, Leland V Miller, Arjumand Rizvi, Sajid Bashir Soofi, Zulfiqar A Bhutta
OBJECTIVES: Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not been examined. METHODS: In a community-based, observational, longitudinal study in a peri-urban settlement of Karachi, Pakistan, we compared the size of the exchangeable zinc pools (EZP) in term SGA and AGA infants at birth and at 6 months of age, hypothesizing that the EZP would be lower in the SGA group...
October 13, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28936229/determinants-of-infant-and-young-child-feeding-practices-by-mothers-in-two-rural-districts-of-sindh-pakistan-a-cross-sectional-survey
#11
Gul Nawaz Khan, Shabina Ariff, Ubaidullah Khan, Atif Habib, Muhammad Umer, Zamir Suhag, Imtiaz Hussain, Zaid Bhatti, Asmat Ullah, Ali Turab, Ali Ahmad Khan, Alba Cecilia Garzon, Mohammad Imran Khan, Sajid Soofi
BACKGROUND: Infant and young child feeding (IYCF) practices during the first two years of life are important for the growth and development of a child. The aim of this study was to assess IYCF practices and its associated factors in two rural districts of Pakistan. METHODS: A cross-sectional study was conducted in two rural districts of Sindh province, Pakistan as part of a stunting prevention project between May and August 2014. A standard questionnaire on IYCF practices recommended by World Health Organization was used to collect information from 2013 mothers who had a child aged between 0 and 23 months...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/28903935/glaucoma-and-intraocular-pressure-in-epic-norfolk-eye-study-cross-sectional-study
#12
Michelle P Y Chan, David C Broadway, Anthony P Khawaja, Jennifer L Y Yip, David F Garway-Heath, Jennifer M Burr, Robert Luben, Shabina Hayat, Nichola Dalzell, Kay-Tee Khaw, Paul J Foster
Objectives  To report the distribution of intraocular pressure (IOP) by age and sex and the prevalence of glaucoma. Design  Community based cross sectional observational study. Setting  EPIC-Norfolk cohort in Norwich and the surrounding rural and urban areas. Participants  8623 participants aged 48-92 recruited from the community who underwent ocular examination to identify glaucoma. Main outcome measures  Prevalence and characteristics of glaucoma, distribution of IOP, and the sensitivity and specificity of IOP for case finding for glaucoma...
September 13, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28852255/temporal-lobe-seizures-presenting-as-abrupt-clinging-behavior-in-a-child
#13
Shabina A Sheth, Nilanjan C Chandra, Ritambhara Y Mehta
True and psychogenic nonepileptic seizures (PNES) go hand in hand. One colors the picture of other. Although it is thought that children carry lower risk for PNES than adults, this may represent the under-diagnosis of this condition in childhood due to few studies on this specific topic. Again, true seizure can be misdiagnosed by dramatic and varied manifestations appearing as psychological phenomena. We report a case of a 9-year-old boy presenting with sudden onset, short lasting, off and on different "melodramatic" episodic behavioral problems with La-Belle' indifference without loss of consciousness, appearing to be of psychogenic origin but finally ended with a diagnosis of temporal lobe epilepsy and responded dramatically with antiepileptics...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28716351/effect-of-provision-of-home-based-curative-health-services-by-public-sector-health-care-providers-on-neonatal-survival-a-community-based-cluster-randomised-trial-in-rural-pakistan
#14
RANDOMIZED CONTROLLED TRIAL
Sajid Soofi, Simon Cousens, Ali Turab, Yaqub Wasan, Shah Mohammed, Shabina Ariff, Zaid Bhatti, Imran Ahmed, Steve Wall, Zulfiqar A Bhutta
BACKGROUND: Although the effectiveness of community mobilisation and promotive care delivered by community health workers in reducing perinatal and neonatal mortality is well established, evidence in support of home-based neonatal resuscitation and infection management is mixed. We assessed the effectiveness of adding training in neonatal bag and mask resuscitation and oral antibiotic therapy for suspected neonatal infections to a basic preventive and promotive interventions package delivered by public sector community-based lady health workers (LHWs) in rural Pakistan...
August 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28529044/synthesis-and-anticancer-activity-of-novel-aza-artemisinin-derivatives
#15
Sampad Jana, Shabina Iram, Joice Thomas, Sandra Liekens, Wim Dehaen
Three series of aza-artemisinin derivatives were synthesized for studies of anticancer activity. The first series of compounds were prepared via copper(I)-catalyzed azide alkyne cycloaddition, so called "click reaction", starting from propargyl derivatives of 11-aza-artemisinin and various azides, whereas the second and third series of compounds were prepared by triazolization reaction starting from enolizable ketones and primary amines connected to artemisinin. In vitro studies of the 23 synthesized artemisinin derivatives unveiled that 9 compounds displayed antiproliferative activity in the low micromolar range, with 5d being the most promising compound showing 50% inhibition of Cem and HeLa cell growth at 0...
July 15, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28507387/multidisciplinary-approach-to-the-prenatal-diagnosis-and-post-natal-management-of-a-large-suprasellar-arachnoid-cyst-a-case-report
#16
Omar Irfan, Heera Nand Rathore, Sarfraz Karim, Shabina Ariff, Aneela Darbar
Arachnoid cysts are intra-arachnoid sacs filled with cerebrospinal fluid representing a rare occurence in neonates. We report the case of a suprasellar arachnoid cyst diagnosed prenatally at 21 weeks gestation on routine obstetric ultrasound. A cystic lesion was picked up incidentally at routine antenatal scan. The cyst was noted to be increasing in size over a series of radiological scans. The cyst was diagnosed as a suprasellar arachnoid cyst compressing the third ventricle and bilateral lateral ventricles...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28407759/a-new-clinical-algorithm-scoring-for-management-of-suspected-foreign-body-aspiration-in-children
#17
Ibrahim A Janahi, Shabina Khan, Prem Chandra, Noora Al-Marri, Ammar Saadoon, Lolwa Al-Naimi, Maryam Al-Thani, William Greer
BACKGROUND: Foreign Body Aspiration (FBA) is a serious problem in children and delays in diagnosis and management can be devastating. The history is often vague, with subtle physical and chest radiograph abnormalities. This study aims to determine the indications for bronchoscopy in children with suspected FBA and evaluate the key clinical and statistically significant predictors of FBA, based on the patients' historical, physical and radiological findings at presentation. METHODS: This is a retrospective observational study, including patients who were admitted between January 2001 to January 2011 with suspected FBA...
April 13, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28401036/anomalous-origin-of-the-left-pulmonary-artery-hemi-truncus-arteriosus
#18
Ali Shabbir Hussain, Mariam Shakir, Shabina Ariff, Rehan Ali, Babar Hassan
Hemi-truncus arteriosus is a rare congenital cardiovascular malformation. It usually presents in infancy and leads to development of progressive pulmonary vascular disease, heart failure, and death. We report a case of hemi truncus arteriosus in a 12-day-old neonate who was successfully managed at our institute.
March 2017: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/28368272/consensus-statement-of-the-indian-academy-of-pediatrics-on-evaluation-and-management-of-autism-spectrum-disorder
#19
Samir Dalwai, Shabina Ahmed, Vrajesh Udani, Nandini Mundkur, S S Kamath, M K C Nair
JUSTIFICATION: Autism Spectrum Disorder (ASD) is a clinically heterogenous condition with a wide range of etiological factors and causing significant public health burden. ASD poses a serious developmental disadvantage to the child in the form of poor schooling, social function and adult productivity. Thus, framing evidence-based national guidelines is a pressing need. PROCESS: The meeting on formulation of national consensus guidelines on neurodevelopmental disorders was organized by Indian Academy of Paediatrics in Mumbai on 18th and 19th December 2015...
May 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28319863/binding-affinity-and-adhesion-force-of-organophosphate-hydrolase-enzyme-with-soil-particles-related-to-the-isoelectric-point-of-the-enzyme
#20
Shah Md Asraful Islam, Shabina Yeasmin, Md Saiful Islam, Md Shariful Islam
The binding affinity of organophosphate hydrolase enzyme (OphB) with soil particles in relation to the isoelectric point (pI) was studied. Immobilization of OphB with soil particles was observed by confocal microscopy, Fourier transform infrared spectroscopy (FT-IR), and Atomic force microscopy (AFM). The calculated pI of OphB enzyme was increased from 8.69 to 8.89, 9.04 and 9.16 by the single, double and triple mutant of OphB enzyme, respectively through the replacement of negatively charged aspartate with positively charged histidine...
July 2017: Ecotoxicology and Environmental Safety
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