keyword
https://read.qxmd.com/read/38321237/evaluation-of-the-effect-of-intraventricular-haemorrhage-on-cerebral-perfusion-in-preterm-neonates-using-three-dimensional-pseudo-continuous-arterial-spin-labelling
#21
JOURNAL ARTICLE
Chi Qin, Xin Zhao, Yanyong Shen, Yu Lu, Sike Li, Chunxiang Zhang, Xiaoan Zhang
BACKGROUND: Intraventricular haemorrhage (IVH) often arises as a cerebral complication directly related to preterm birth. The impaired autoregulation of cerebral blood flow is closely associated with IVH in preterm neonates. Three-dimensional pseudo-continuous arterial spin labelling (3D-pCASL) is a noninvasive magnetic resonance imaging (MRI) technique used for evaluating cerebral perfusion. OBJECTIVE: This study aimed to compare cerebral blood flow values among three distinct groups using 3D-pCASL: preterm neonates with and without IVH and preterm neonates at term-equivalent age...
February 7, 2024: Pediatric Radiology
https://read.qxmd.com/read/38310200/validation-of-winrop-algorithm-as-screening-tool-of-retinopathy-of-prematurity-among-egyptian-preterm-neonates
#22
JOURNAL ARTICLE
Asmaa Fares, Sherif Abdelmonaim, Dina Sayed, Sherin Sadek, Abdulrahman Abdulrazek, Youssef Helmy, Sara Maher
BACKGROUND: Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness worldwide. Proper screening for ROP can prevent loss of vision. WINROP (weight, insulin-like growth factor 1, neonatal, retinopathy of prematurity) is an online surveillance system based on gestational age, birth weight and weekly weight gain that can predict infants at risk of sight-threatening retinopathy of prematurity. AIMS: To evaluate the diagnostic accuracy of WINROP algorithm in detecting sight-threatening ROP in Egyptian preterm neonates...
February 3, 2024: Eye
https://read.qxmd.com/read/38301326/cannabidiol-reduces-intraventricular-hemorrhage-brain-damage-preserving-myelination-and-preventing-blood-brain-barrier-dysfunction-in-immature-rats
#23
JOURNAL ARTICLE
Aarón Del Pozo, María de Hoz-Rivera, Angela Romero, María Villa, María Martínez, Laura Silva, Fabiana Piscitelli, Vincenzo Di Marzo, Ana Gutiérrez-Rodríguez, William Hind, José Martínez-Orgado
Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. This study assessed the potential neuroprotective effects of cannabidiol (CBD) in an IVH model using immature rats. IVH was induced in 1-day-old (P1) Wistar rats by left periventricular injection of Clostridial collagenase. Some rats received CBD prenatally (10 ​mg/kg i.p. to the dam) and then 5 ​mg/kg i.p. 6, 30 and 54 ​h after IVH (IVH+CBD, n ​= ​30)...
January 31, 2024: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://read.qxmd.com/read/38279057/incidence-of-brain-injuries-in-a-large-cohort-of-very-preterm-and-extremely-preterm-infants-at-term-equivalent-age-results-of-a-single-tertiary-neonatal-care-center-over-10%C3%A2-years
#24
JOURNAL ARTICLE
Karla Drommelschmidt, Thomas Mayrhofer, Britta Hüning, Anja Stein, Borek Foldyna, Bernd Schweiger, Ursula Felderhoff-Müser, Selma Sirin
OBJECTIVES: Cerebral magnetic resonance imaging (cMRI) at term-equivalent age (TEA) can detect brain injury (BI) associated with adverse neurological outcomes in preterm infants. This study aimed to assess BI incidences in a large, consecutive cohort of preterm infants born < 32 weeks of gestation, the comparison between very (VPT, ≥ 28 + 0 to < 32 + 0 weeks of gestation) and extremely preterm infants (EPT, < 28 + 0 weeks of gestation) and across weeks of gestation...
January 27, 2024: European Radiology
https://read.qxmd.com/read/38276984/assessing-adverse-pregnancy-outcomes-in-women-with-uncontrolled-asthma-vs-mild-asthma-a-retrospective-comparative-analysis
#25
JOURNAL ARTICLE
Ali Taner Anuk, Atakan Tanacan, Özgür Kara, Dilek Sahin
PURPOSE: The aim of this study was to evaluate perinatal outcomes between the uncontrolled asthma group and the mild asthma group and to reveal the relationship between disease severity and adverse maternal-fetal outcomes in this study. METHODS: This retrospective cohort study analyzed 180 pregnant women diagnosed with asthma, hospitalized, and delivered at our center between September 1, 2019, and December 1, 2021. We compared two groups: 160 with mild asthma and 20 with uncontrolled asthma...
January 26, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38275024/the-frequency-of-intraventricular-hemorrhage-and-its-risk-factors
#26
JOURNAL ARTICLE
Mohsen Haghshenas-Mojaveri, Forough Alikabranya Omran, Soraya Khafri, Raheleh Mehraein, Ebrahim Hejazian, Zahr Akbarian-Rad
BACKGROUND: Intraventricular hemorrhage) IVH(is the most prevalent type of cerebrovascular accident in premature infants, which can result in lasting neurological complications. The aim of this study was to ascertain the frequency of IVH and its associated risk factors within our particular context. MATERIALS AND METHODS: This cross-sectional study was carried out in a tertiary neonatal intensive care unit of a maternal and neonatal hospital from September 2018 to August 2019...
January 24, 2024: Current Pediatric Reviews
https://read.qxmd.com/read/38270816/clinical-impact-of-craniectomy-on-shunt-dependent-hydrocephalus-after-intracerebral-hemorrhage-a-propensity-score-matched-analysis
#27
JOURNAL ARTICLE
Shin Heon Lee, Myeong Jin Ko, Young-Seok Lee, Joon Cho, Yong-Sook Park
PURPOSE: A consensus on decompressive craniectomy for intracerebral hemorrhage (ICH) has not yet been established. We aimed to investigate the development of shunt-dependent hydrocephalus based on the method of ICH surgery, with a focus on craniectomy. METHODS: We retrospectively enrolled 458 patients with supratentorial ICH who underwent surgical hematoma evacuation between April 2005 and December 2021 at two independent stroke centers. Multivariate analyses were performed to characterize risk factors for postoperative shunt-dependent hydrocephalus...
January 25, 2024: Acta Neurochirurgica
https://read.qxmd.com/read/38270182/laryngeal-mask-airway-surfactant-administration-for-prevention-of-morbidity-and-mortality-in-preterm-infants-with-or-at-risk-of-respiratory-distress-syndrome
#28
REVIEW
Mohamed E Abdel-Latif, Elizabeth Walker, David A Osborn
BACKGROUND: Laryngeal mask airway surfactant administration (S-LMA) has the potential benefit of surfactant administration whilst avoiding endotracheal intubation and ventilation, ventilator-induced lung injury and bronchopulmonary dysplasia (BPD). OBJECTIVES: To evaluate the benefits and harms of S-LMA either as prophylaxis or treatment (rescue) compared to placebo, no treatment, or intratracheal surfactant administration via an endotracheal tube (ETT) with the intent to rapidly extubate (InSurE) or extubate at standard criteria (S-ETT) or via other less-invasive surfactant administration (LISA) methods on morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome (RDS)...
January 25, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38263492/textbook-outcomes-among-patients-with-aneurysmal-subarachnoid-hemorrhage-following-endovascular-treatment
#29
JOURNAL ARTICLE
Zisheng Liu, Yuhao Tan, Yanpeng Wei, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Pengfei Yang, Jun Sun, Jianmin Liu, Qiao Zuo
INTRODUCTION: The case fatality rate among patients with aneurysmal subarachnoid hemorrhage (aSAH) has decreased progressively, with numerous patients subjected to contemporary paradigms that minimize the use of agonizing therapeutic processes. The concept of the "Textbook Outcome" (TO), a composite outcome that highlights numerous favorable outcomes, was developed in the context of gastrointestinal tumor surgeries and expeditiously extended across diverse surgical spheres. The aim of this study was to explore the factors hindering the achievement of optimal prognoses in postinterventional aSAH patients, employ textbook outcomes, and establish predictive models...
January 23, 2024: Neurology and Therapy
https://read.qxmd.com/read/38261286/-anatomo-functional-state-of-the-central-retina-in-premature-infants-with-intraventricular-hemorrhage-and-retinopathy-of-prematurity
#30
JOURNAL ARTICLE
I B Astasheva, M R Guseva, R Atamuradov, V V Marenkov, Yu A Kyun, E I Lobanova
OBJECTIVE: Assessment of the anatomo-functional state of the central retina in children with intraventricular hemorrhage (IVH) and retinopathy of prematurity (ROP) in the long-term period. MATERIAL AND METHODS: We examined 51 patients (102 eyes) born 25-34 weeks' of gestation (birth weight 700-2290 g), aged 8.83±3.5 years, and 18 children (36 eyes) born prematurely aged 10.8±3.2 years. The children underwent standard ophthalmologic examination, optical coherence tomography (OCT) and visual evoked potentials (VEP)...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38256563/is-parity-a-risk-factor-for-late-preterm-birth-results-from-a-large-cohort-study
#31
JOURNAL ARTICLE
Lior Kashani-Ligumsky, Ran Neiger, Ella Segal, Ronnie Cohen, Miriam Lopian
Most preterm births occur in the late preterm period. While prematurity-related adverse outcomes are significantly diminished when birth occurs during this period, these infants are still at increased risk of complications. Parity affects the incidence of obstetric complications. The purpose of this study was to determine whether parity impacts the risk of spontaneous late preterm birth (SLPTB) and associated complications. A retrospective observational cohort study was conducted. Patients were divided into three study groups according to parity...
January 12, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38253913/histological-chorioamnionitis-and-pathological-stages-on-very-preterm-infant-outcomes
#32
JOURNAL ARTICLE
Jiajia Duan, Falin Xu, Chaoya Zhu, Ju Wang, Xiaoli Zhang, Yiran Xu, Bingbing Li, Xirui Peng, Jinjin Zhu, Xiaoyang Wang, Changlian Zhu
AIMS: Histological chorioamnionitis (HCA) is a condition linked to preterm birth and neonatal infection and its relationship with various pathological stages in extremely preterm neonates, and with their associated short- and long-term consequences, remains a subject of research. This study investigated the connection between different pathological stages of HCA and both short-term complications and long-term outcomes in preterm infants born at or before 32 weeks of gestational age...
January 22, 2024: Histopathology
https://read.qxmd.com/read/38238178/descriptive-registry-study-on-outcome-and-complications-of-external-ventricular-drainage-treatment-of-intraventricular-haemorrhage-in-a-danish-cohort-a-study-protocol
#33
JOURNAL ARTICLE
Chenghao Gu, Mette Haldrup, Mads Rasmussen, Stig Dyrskog, Claus Ziegler Simonsen, Mads Hjortdal Grønhøj, Frantz Rom Poulsen, Thor Busse, Joakim Wismann, Birgit Debrabant, Anders Rosendal Korshoej
INTRODUCTION: Intraventricular haemorrhage (IVH) is associated with high morbidity and mortality. External ventricular drainage (EVD) has been shown to decrease mortality. Although EVD is widely used, outcome and complication rates in EVD-treated patients with IVH are not fully elucidated. This study aims to describe EVD complication rates and outcomes in patients with primary and secondary IVH at two university hospitals in Denmark. The study will provide a historical reference of relevant endpoints for use in future clinical trials involving patients with IVH...
January 18, 2024: BMJ Open
https://read.qxmd.com/read/38235838/non-pharmacological-interventions-for-the-prevention-of-pain-during-endotracheal-suctioning-in-ventilated-neonates
#34
JOURNAL ARTICLE
Sofie Pirlotte, Katrien Beeckman, Isabel Ooms, Filip Cools
BACKGROUND: Pain, when treated inadequately, puts preterm infants at a greater risk of developing clinical and behavioural sequelae because of their immature pain system. Preterm infants in need of intensive care are repeatedly and persistently exposed to noxious stimuli, and this happens during a critical window of their brain development with peak rates of brain growth, exuberant synaptogenesis and the developmental regulation of specific receptor populations. Nearly two-thirds of infants born at less than 29 weeks' gestation require mechanical ventilation for some duration during the newborn period...
January 18, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38234113/is-the-frequency-of-imaging-markers-still-a-predictor-for-revised-intracerebral-hemorrhage-expansion
#35
JOURNAL ARTICLE
Lei Song, Hang Zhou, Jun Cheng, Wenmin Guo, Yu Ye, Rujia Wang, Jiao Chen, Hui Xiong, Ji Zhang, Dongfang Tang, Liwei Zou, Lianghong Kuang, Xiaoming Qiu, Tingting Guo
INTRODUCTION: Frequency of imaging markers (FIM) has been described as a novel predictor for hematoma expansion after intracerebral hemorrhage (ICH). A revised definition of hematoma expansion that incorporates intraventricular hemorrhage (IVH) growth, that is, revised hematoma expansion (RHE), has also been proposed. Nevertheless, the associations between FIM and IVH growth or RHE remains unexplored. The objective of this study was to assess the influence and performance of the FIM on two types...
January 17, 2024: European Stroke Journal
https://read.qxmd.com/read/38231413/glycogen-synthase-kinase-3%C3%AE-inhibitor-vp3-15-ameliorates-neurogenesis-neuronal-loss-and-cognitive-impairment-in-a-model-of-germinal-matrix-intraventricular-hemorrhage-of-the-preterm-newborn
#36
JOURNAL ARTICLE
Isabel Atienza-Navarro, Angel Del Marco, Pilar Alves-Martinez, Maria de Los Angeles Garcia-Perez, Alvaro Raya-Marin, Isabel Benavente-Fernandez, Carmen Gil, Ana Martinez, Simon Lubian-Lopez, Monica Garcia-Alloza
Advances in neonatology have significantly reduced mortality rates due to prematurity. However, complications of prematurity have barely changed in recent decades. Germinal matrix-intraventricular hemorrhage (GM-IVH) is one of the most severe complications of prematurity, and these children are prone to suffer short- and long-term sequelae, including cerebral palsy, cognitive and motor impairments, or neuropsychiatric disorders. Nevertheless, GM-IVH has no successful treatment. VP3.15 is a small, heterocyclic molecule of the 5-imino-1,2,4-thiadiazole family with a dual action as a phosphodiesterase 7 and glycogen synthase kinase-3β (GSK-3β) inhibitor...
January 17, 2024: Translational Stroke Research
https://read.qxmd.com/read/38222756/magnitude-of-dural-tear-and-its-associated-factors-among-patients-with-depressed-skull-fracture
#37
JOURNAL ARTICLE
Yohannis D Molla, Hirut T Alemu, Samrawit A Kassa, Deresse A Gebrehana, Samuel A Abera, Helina E Tebeje, Abel G Demise
INTRODUCTION: Trauma is a huge problem seen in developed countries as well as developing countries. Head injury is a major factor responsible for mortality in young populations. Up to 6% of all head injuries and 11% of severe head traumas might result in a depressed skull fracture (DSF), a catastrophic injury. The aim of this study was to determine the prevalence of dural tear and to identify its predictors. METHOD: A retrospective review of medical records of all patients operated on for DSFs at the University Comprehensive Specialized Hospital from 1 January 2021 to 1 January 2023 G...
January 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38218082/early-red-blood-cell-transfusion-and-the-occurrence-of-intraventricular-hemorrhage-in-very-preterm-infants
#38
JOURNAL ARTICLE
Aleksandra Skubisz, Linda S de Vries, Sophie J Jansen, Hilde van der Staaij, Enrico Lopriore, Sylke J Steggerda
BACKGROUND: Preterm infants are at risk of developing both intraventricular hemorrhage (IVH) and anemia of prematurity. Several studies reported an association between early postnatal red blood cell (RBC) transfusion and IVH, however the timing and causality between these two remains unclear. AIMS: To describe the temporal sequence between administration of early RBC transfusion (within the first week of life) and diagnosis of IVH in very preterm infants. STUDY DESIGN: Retrospective single center case-series...
February 2024: Early Human Development
https://read.qxmd.com/read/38212403/retinopathy-of-prematurity-screening-prevalence-and-risk-factors-of-ophthalmic-complications-in-non-treated-preterm-infants
#39
JOURNAL ARTICLE
Jacob I Strelnikov, Rakesh Rao, Shahriyar Majidi, Gregg Lueder, Andrew Lee, Margaret M Reynolds
INTRODUCTION: Retinopathy of prematurity (ROP) is a vision-threatening disease of premature infants. Practice guidelines recommend that all infants screened for ROP receive follow-up eye examinations to screen for ophthalmic complications.1 The purpose of this study was to identify risk factors for the development of strabismus, amblyopia, high refractive error, and cataracts among ROP-screened, non-treated infants. METHODS: Retrospective single-centre study of ROP-screened, non-treated premature infants with ophthalmic follow-up...
January 11, 2024: Eye
https://read.qxmd.com/read/38200247/continuous-irrigation-with-thrombolytics-for-intraventricular-hemorrhage-case-control-study
#40
JOURNAL ARTICLE
Diego A Carrera, Marc C Mabray, Michel T Torbey, Jason E Andrada, Danika E Nelson, Preeyaporn Sarangarm, Heather Spader, Chad D Cole, Andrew P Carlson
Intraventricular hemorrhage (IVH) is a complication of a spontaneous intracerebral hemorrhage. Standard treatment is with external ventricular drain (EVD). Intraventricular thrombolysis may improve mortality but does not improve functional outcomes. We present our initial experience with a novel irrigating EVD (IRRAflow) that automates continuous irrigation with thrombolysis.Single-center case-control study including patients with IVH treated with EVD compared to IRRAflow. We compared standard demographics, treatment, and outcome parameters between groups...
January 10, 2024: Neurosurgical Review
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