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https://www.readbyqxmd.com/read/28090292/a-new-look-at-bronchopulmonary-dysplasia-postcapillary-pathophysiology-and-cardiac-dysfunction
#1
Arvind Sehgal, Andra Malikiwi, Eldho Paul, Kenneth Tan, Samuel Menahem
Pulmonary hypertension (PH) and right ventricular function are the focus of cardiovascular effects of bronchopulmonary dysplasia (BPD). We assessed cardiac indexes reflecting systemic afterload and pulmonary venous back pressure as pathophysiologic factors. Cardiac parameters were measured by conventional echocardiography in 20 preterm infants with severe BPD and compared with those of 10 preterm infants with no BPD and 20 healthy term infants. In infants with severe BPD, PH was noted in 5 (25%) by tricuspid regurgitation Doppler jet ≥2...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28090255/clinical-utility-of-echocardiography-for-the-diagnosis-and-prognosis-in-children-with-bronchopulmonary-dsyplasia
#2
Young Earl Choi, Hwa Jin Cho, Eun Song Song, In Seok Jeong, Namsik Yoon, Young Youn Choi, Jae Sook Ma, Young Kuk Cho
BACKGROUND: Bronchopulmonary dysplasia (BPD) may result in chronic pulmonary artery hypertension and right ventricular (RV) dysfunction. Various echocardiographic assessments of RV dysfunction have been used to determine whether echocardiographic measurements of premature infants with BPD could provide sensitive measures of RV function that correlates with BPD severity. METHODS: Twenty-eight control subjects without BPD (non BPD group), 28 patients with mild BPD, 11 patients with moderate BPD, and six patients with severe BPD underwent echocardiograms with standard measurement such as ejection fraction by M-mode, tricuspid regurgitation pressure gradient, myocardial performance index (MPI) derived from pulse Doppler, and tissue Doppler imaging (TDI) measurements...
December 2016: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28089438/a-retrospective-comparison-of-biliopancreatic-diversion-with-duodenal-switch-with-single-anastomosis-duodenal-switch-sips-stomach-intestinal-pylorus-sparing-surgery-at-a-single-institution-with-two-year-follow-up
#3
Amit Surve, Hinali Zaveri, Daniel Cottam, LeGrand Belnap, Austin Cottam, Samuel Cottam
BACKGROUND: The traditional duodenal switch is performed using a Roux-en-Y configuration. This procedure has proven to be the most effective procedure for long-term weight loss and co-morbidity reduction. Recently, stomach intestinal pylorus sparing surgery (SIPS) has been introduced as a simpler and potentially safer variation of the duodenal switch (DS). It is a single anastomosis end-to-side proximal duodeno-ileal bypass with a sleeve gastrectomy. In this study, we compare our outcomes between biliopancreatic diversion with duodenal switch (BPD-DS) and SIPS at 2 years...
December 2, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28081574/gstp1-and-cyp2b6-genetic-polymorphisms-and-the-risk-of-bronchopulmonary-dysplasia-in-preterm-neonates
#4
Sophia Zachaki, Aggeliki Daraki, Elena Polycarpou, Chrysa Stavropoulou, Kalliopi N Manola, Stavroula Gavrili
Objectives Antioxidant response plays a key role in bronchopulmonary dysplasia (BPD) pathogenesis. The glutathione-S-tranferases pi 1 (GSTP1) and cytochrome P450 (CYP) detoxification enzymes protect cells from oxidative damage. The aim of the study was to investigate whether the A(313)G GSTP1 and G(516)T CYP2B6 inactivating polymorphisms could be associated with BPD susceptibility. Study Design To test this hypothesis, we conducted a case-control study enrolled 138 premature neonates ≤32 weeks of gestational age; of the 138, 46 developed BPD and 92 did not develop BPD...
January 12, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28079864/bronchopulmonary-dysplasia-and-pulmonary-hypertension-a-meta-analysis
#5
G Al-Ghanem, P Shah, S Thomas, L Banfield, S El Helou, C Fusch, A Mukerji
OBJECTIVE: Pulmonary hypertension (PH) is a complication of bronchopulmonary dysplasia (BPD) but the true impact of PH in patients with BPD remains unclear. We sought to systematically review and meta-analyze incidence of PH in BPD and compare clinical outcomes of BPD patients with PH to those without PH in preterm infants. STUDY DESIGN: Medline, Embase, PsychINFO and CINAHL were searched from January 2000 through December 2015. Cohort, case-control and randomized studies were included...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28078790/cavum-septi-pellucidi-csp-ratio-a-marker-for-partial-agenesis-of-the-fetal-corpus-callosum
#6
K Karl, T Esser, K S Heling, R Chaoui
OBJECTIVE: While complete agenesis of the corpus callosum (CC) is often suspected on fetal ultrasound due to the absence of the cavum septi pellucidi (CSP), the suspicion of a partial agenesis (pACC) is still a challenge since the CSP is almost always present in these conditions. Aim of the study was to measure the length and width of the CSP and to calculate the ratio of the length to width as CSP-Ratio in fetuses with pACC and to compare with values from normal fetuses. PATIENTS: In a case-control study the CSP was measured in the axial plane of the fetal head in 323 normal fetuses between 20 and 34 weeks' gestation and reference ranges in relation to the biparietal diameter (BPD) were constructed...
January 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28078089/the-specificity-of-emotion-dysregulation-in-adolescents-with-borderline-personality-disorder-comparison-with-psychiatric-and-healthy-controls
#7
Marina Ibraheim, Allison Kalpakci, Carla Sharp
BACKGROUND: Research has supported the notion that emotion dysregulation is a core feature of BPD. However, given that this feature is typical of healthy adolescents as well as adolescents with other psychiatric disorders, the specificity of emotion dysregulation to BPD in this age group has not yet been determined. The overall aim of this study was to examine emotion dysregulation in adolescent inpatients with BPD compared with non-BPD inpatient adolescents and healthy non-clinical adolescents, taking into account both global emotion dysregulation deficits and more specific impairments...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/28077135/comorbidity-study-of-borderline-personality-disorder-applying-association-rule-mining-to-the-taiwan-national-health-insurance-research-database
#8
Cheng-Che Shen, Li-Yu Hu, Ya-Han Hu
BACKGROUND: Borderline personality disorder (BPD) is a complex clinical state with highly polymorphic symptoms and signs. Studies have demonstrated that people with a BPD diagnosis are likely to have numerous co-occurring psychiatric disorders and physical comorbidities. The aim of our study was to obtain further insight about the associations among comorbidities of BPD and to demonstrate the practicality of using association rule mining (ARM) technique in clinical databases. METHODS: A retrospective case-control study was conducted on information of 1460 patients (292 BPD patients and 1168 control patients) selected from the Taiwan National Health Insurance Research Database...
January 11, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28073162/refractory-subacute-steatohepatitis-after-biliopancreatic-diversion
#9
Sander Lefere, Anne Hoorens, Sarah Raevens, Roberto Troisi, Xavier Verhelst, Hans Van Vlierberghe, Anja Geerts
Steatohepatitis development after the biliopancreatic diversion (BPD) procedure for morbid obesity has rarely been reported. We present a case of fatal recurrent steatohepatitis post-PBD despite repeated liver transplantations. This article is protected by copyright. All rights reserved.
January 10, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28072044/predicting-nonsuicidal-self-injury-in-borderline-personality-disorder-using-ecological-momentary-assessment
#10
Brooke A Ammerman, Thomas M Olino, Emil F Coccaro, Michael S McCloskey
Borderline personality disorder (BPD) is a highly comorbid disorder, and these comorbidities increase the impairment associated with BPD. For example, depression, which occurs in the majority of individuals with BPD, increases the likelihood of an individual with BPD to engage in nonsuicidal self-injury (NSSI). Little research, however, has investigated potential mechanisms of NSSI engagement in this population. The current study aimed to fill this gap by examining momentary experiences, levels of distress tolerance, and NSSI among 51 individuals meeting current diagnostic criteria for BPD and a comorbid depressive disorder...
January 10, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28072043/compelled-to-risk-does-sexual-compulsivity-explain-the-connection-between-borderline-personality-disorder-features-and-number-of-sexual-partners
#11
Charles Jardin, Carla Sharp, Lorra Garey, Salome Vanwoerden, Nic Crist, Jon D Elhai, Michael J Zvolensky
Having more sexual partners increases the likelihood of new HIV infections among women. Women with more borderline personality disorder (BPD) features have been known to have greater numbers of sexual partners. However, the mechanisms linking BPD features with more sexual partners remain to be clarified. Sexual compulsivity (lack of control, increased distress over sexual behavior) may be one such explanatory factor, as it overlaps with BPD features (e.g., impulsivity, negative affectivity). The present study examined whether sexual compulsivity explained the relation of BPD features with number of sexual partners among a diverse sample of college females (N = 1,326)...
January 10, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28072041/interpersonal-threat-sensitivity-in-borderline-personality-disorder-an-eye-tracking-study
#12
Katja Bertsch, Marlene Krauch, Katharina Stopfer, Katrin Haeussler, C Herpertz, Matthias Gamer
Threat sensitivity is a prominent predictor of interpersonal dysfunctions in borderline personality disorder (BPD), leading to intense, aversive feelings of threat and eventually dysfunctional behaviors, such as aggression. In the present study, BPD patients and healthy volunteers classified angry, fearful, neutral, and happy faces presented for 150 ms or 5,000 ms to investigate initial saccades and facial scanning. Patients more often wrongly identified anger, responded slower to all faces, and made faster saccades towards the eyes of briefly presented neutral faces and slower saccades away from fearful eyes compared with healthy volunteers...
January 10, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28072040/altered-empathy-for-psychological-and-physical-pain-in-borderline-personality-disorder
#13
Vera Flasbeck, Björn Enzi, Martin Brüne
Many patients with borderline personality disorder (BPD) experience difficulties in empathizing with others and are sensitive to social exclusion. Accordingly, the authors developed a novel Social Interaction Empathy Task to examine empathy for physical and psychological pain from first- and third-person perspectives. Fifty female patients with BPD and forty-eight controls matched for age and gender were included. Alexithymia was also measured. Patients with BPD rated neutral and psychologically painful situations as more painful than healthy controls, and patients with BPD rated psychological pain as more intense in the first-person perspective than in the third-person perspective...
January 10, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28072039/a-mother-s-borderline-personality-disorder-and-her-sensitivity-autonomy-support-hostility-fearful-disoriented-behavior-and-role-reversal-with-her-young-child
#14
Jenny Macfie, Gretchen Kurdziel, Rebecca M Mahan, Stephanie Kors
There is some evidence that maternal borderline personality disorder (BPD) adversely affects parenting in infancy, resulting in disorganized attachment, which longitudinally predicts BPD symptoms in adulthood. We examined parenting related to disorganized attachment beyond infancy in offspring of mothers with BPD, when parenting becomes a goal-corrected partnership. We observed puzzle solving in a low socioeconomic status (SES) sample of mothers with BPD and their children ages 4-7, n = 36, and normative comparisons, n = 34...
January 10, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28068498/adapting-dialectical-behavior-therapy-for-the-treatment-of-dissociative-identity-disorder
#15
Brad Foote, Kim Van Orden
Dialectical Behavior Therapy (DBT), created by Marsha Linehan, has been shown to be an effective therapy for the treatment of borderline personality disorder (BPD) and for suicidal and self-harming behavior. Dissociative identity disorder (DID) is a complex post-traumatic disorder which is highly comorbid with BPD, shares a number of clinical features with BPD, and which like BPD features a high degree of suicidality. The DID treatment literature emphasizes the importance of a staged approach, beginning with the creation of a safe therapeutic frame prior to addressing traumatic material; DBT is also a staged treatment, in which behavioral and safety issues are addressed in Stage 1, and trauma work reserved for Stage 2...
December 31, 2016: American Journal of Psychotherapy
https://www.readbyqxmd.com/read/28067830/bronchopulmonary-dysplasia-chronic-lung-disease-of-infancy-and-long-term-pulmonary-outcomes
#16
REVIEW
Lauren M Davidson, Sara K Berkelhamer
Bronchopulmonary dysplasia (BPD) is a chronic lung disease most commonly seen in premature infants who required mechanical ventilation and oxygen therapy for acute respiratory distress. While advances in neonatal care have resulted in improved survival rates of premature infants, limited progress has been made in reducing rates of BPD. Lack of progress may in part be attributed to the limited therapeutic options available for prevention and treatment of BPD. Several lung-protective strategies have been shown to reduce risks, including use of non-invasive support, as well as early extubation and volume ventilation when intubation is required...
January 6, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28067624/modelling-bronchopulmonary-dysplasia-in-mice-how-much-oxygen-is-enough
#17
Claudio Nardiello, Ivana Mižíková, Diogo M Silva, Jordi Ruiz-Camp, Konstantin Mayer, István Vadász, Susanne Herold, Werner Seeger, Rory E Morty
Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective was to develop a robust hyperoxia‑based mouse model of BPD that recapitulated the pathological perturbations to lung structure noted in infants with BPD. Newborn mouse pups were exposed to a varying fraction of oxygen in the inspired air (FiO2) and a varying window of hyperoxia exposure, after which lung structure was assessed by design‑based stereology with systemic uniform random sampling...
December 14, 2016: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28065816/development-of-customized-fetal-growth-charts-in-twins
#18
Tullio Ghi, Federico Prefumo, Anna Fichera, Mariano Lanna, Enrico Periti, Nicola Persico, Elsa Viora, Giuseppe Rizzo
BACKGROUND: Twin gestations are at significantly higher risk of fetal growth restriction in comparison with singletons. Using fetal biometric charts customized for obstetrical and parental characteristics may facilitate accurate assessment of fetal growth. OBJECTIVE(S): To construct reference charts for gestation of fetal biometric parameters stratified by chorionicity and customized for obstetrical and parental characteristics. STUDY DESIGN: Fetal biometric measurements obtained from serial ultrasound examinations in uncomplicated twin pregnancies delivering after 36 weeks of gestation were collected by 19 Italian fetal medicine units under the auspices of the Società Italiana di Ecografia Ostetrica e Ginecologica...
January 5, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28063223/neurally-adjusted-ventilatory-assist-for-infants-under-prolonged-ventilation
#19
Juyoung Lee, Han-Suk Kim, Young Hwa Jung, Chang Won Choi, Yong Hoon Jun
BACKGROUND: Severe bronchopulmonary dysplasia (BPD) often leads to prolonged mechanical ventilation lasting several months. Cyanotic episodes frequently occur in these patients, which necessitate long-term sedation and/or intermittent muscle paralysis. Neurally adjusted ventilatory assist (NAVA) might provide precisely the amount of support that these patients need without sedation. METHODS: We reviewed the medical records of preterm infants who underwent a tracheostomy and required mechanical ventilation for more than 6 months during a period of 6 years...
January 7, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28062834/prenatal-no2-exposure-and-ultrasound-measures-of-foetal-growth-a-prospective-cohort-study-in-wuhan-china
#20
Weiye Wang, Chunrong Zhong, Li Huang, Xuezhen Zhou, Renjuan Chen, Jiangyue Wu, Xiating Li, Ting Xiong, Chaoqun Liu, Mei Xiao, Xuefeng Yang, Liping Hao, Nianhong Yang, Sheng Wei
OBJECTIVES: To examine the relationship between prenatal nitrogen dioxide (NO2) exposure and foetal growth in a prospective cohort of 1001 Chinese women. METHODS: The maternal NO2 exposure levels were estimated using land-use regression models based on home address. The biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL) and estimated foetal weight (EFW) were evaluated via ultrasonography. The multiple linear regression model was used to adjust for confounders, and the mixed-effect model was used to assess longitudinal effect...
January 6, 2017: Occupational and Environmental Medicine
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