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https://www.readbyqxmd.com/read/28079308/greater-temperature-sensitivity-of-plant-phenology-at-colder-sites-implications-for-convergence-across-northern-latitudes
#1
Janet Prevéy, Mark Vellend, Nadja Rüger, Robert D Hollister, Anne D Bjorkman, Isla H Myers-Smith, Sarah C Elmendorf, Karin Clark, Elisabeth J Cooper, Bo Elberling, Anna Maria Fosaa, Gregory H R Henry, Toke T Høye, Ingibjörg Svala Jónsdóttir, Kari Klanderud, Esther Lévesque, Marguerite Mauritz, Ulf Molau, Susan M Natali, Steven F Oberbauer, Zoe A Panchen, Eric Post, Sabine B Rumpf, Niels M Schmidt, Ted Schuur, Phillip R Semenchuk, Tiffany Troxler, Jeffrey M Welker, Christian Rixen
Warmer temperatures are accelerating the phenology of organisms around the world. Temperature sensitivity of phenology might be greater in colder, higher-latitude sites than in warmer regions, in part because small changes in temperature constitute greater relative changes in thermal balance at colder sites. To test this hypothesis, we examined up to 20 years of phenology data for 47 tundra plant species at 18 high-latitude sites along a climatic gradient. Across all species, the timing of leaf emergence and flowering were more sensitive to a given increase in summer temperature at colder than warmer high-latitude locations...
January 11, 2017: Global Change Biology
https://www.readbyqxmd.com/read/27936278/the-relationship-between-grammatical-development-and-disfluencies-in-preschool-children-who-stutter-and-those-who-recover
#2
Julia Hollister, Amanda Owen Van Horne, Patricia Zebrowski
Purpose: The dual diathesis stressor model indicates that a mismatch between a child's endogenous linguistic abilities and exogenous linguistic contexts is one factor that contributes to stuttering behavior. In the present study, we used a developmental framework to investigate if reducing the gap between endogenous and exogenous linguistics factors would result in less disfluency for typical children, children who recover from stuttering (CWS-R), and children who persist. Method: Children between 28 and 43 months of age participated in this study: 8 typical children, 5 CWS-R, and 8 children who persist...
December 9, 2016: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/27935209/tailoring-the-physicochemical-and-shape-memory-properties-of-the-biodegradable-polymer-poly-glycerol-dodecanoate-via-curing-conditions
#3
Loran D Solorio, Martin L Bocks, Scott J Hollister
A major challenge in the repair and regeneration of soft tissue damage occurring as a result of aging, injury, or disease is recapitulating the biomechanical properties of the native tissue. Ideally, a candidate biomaterial for soft tissue engineering applications should be biocompatible, nonlinearly elastic to match soft tissue mechanical behavior, biodegradable to enable tissue remodeling, and tailorable to achieve a range of nonlinear elastic mechanical properties to match specific soft tissues. In addition, for cardiac and other applications, the biomaterial should have shape memory characteristics to facilitate minimally invasive and/or catheter-based delivery...
December 9, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27896978/development-and-performance-of-text-mining-algorithms-to-extract-socioeconomic-status-from-de-identified-electronic-health-records
#4
Brittany M Hollister, Nicole A Restrepo, Eric Farber-Eger, Dana C Crawford, Melinda C Aldrich, Amy Non
Socioeconomic status (SES) is a fundamental contributor to health, and a key factor underlying racial disparities in disease. However, SES data are rarely included in genetic studies due in part to the difficultly of collecting these data when studies were not originally designed for that purpose. The emergence of large clinic-based biobanks linked to electronic health records (EHRs) provides research access to large patient populations with longitudinal phenotype data captured in structured fields as billing codes, procedure codes, and prescriptions...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27764088/ten-simple-rules-for-digital-data-storage
#5
Edmund M Hart, Pauline Barmby, David LeBauer, François Michonneau, Sarah Mount, Patrick Mulrooney, Timothée Poisot, Kara H Woo, Naupaka B Zimmerman, Jeffrey W Hollister
No abstract text is available yet for this article.
October 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27711917/advances-in-3-dimensional-printing-in-otolaryngology-a-review
#6
Kyle K VanKoevering, Scott J Hollister, Glenn E Green
Importance: Three-dimensional (3-D) printing is an exponentially growing technology that enables the use of a patient's image data to create patient-specific models, devices, and implants. Three-dimensional printing, developed in the 1980s, has emerged in the past decade with the potential to create new paradigms in personalized medicine. Observations: The field of otolaryngology has advanced many current and evolving future medical applications of 3-D printing...
October 6, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27593871/different-responses-in-induction-of-allergen-specific-immunoglobulin-g4-and-ige-blocking-factors-for-three-mite-subcutaneous-immunotherapy-products
#7
Kyung Hee Park, Sang Chul Lee, Young Woong Son, Kyoung Yong Jeong, Yoo Seob Shin, Jung U Shin, Da Woon Sim, Hye Jung Park, Jae Hyun Lee, Kwang Hoon Lee, Jung Won Park
PURPOSE: Specific immunoglobulin G4 (sIgG4) and immunoglobulin E (IgE)-blocking factors produced by subcutaneous immunotherapy (SCIT) play a critical role in the induction of allergen tolerance. However, comparative studies of available SCIT reagents on the induction of sIgG4 are limited. We compared increases in sIgG4 for three different house dust mite (HDM) SCIT reagents. MATERIALS AND METHODS: Seventy-two HDM sensitized allergic patients were enrolled and classified into four groups: 1) control (n=27), 2) SCIT with Hollister-Stier® (n=19), 3) Tyrosine S® (n=16), and 4) Novo-Helisen® (n=10)...
November 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27582889/the-mucosal-microbiota-in-a-young-child-with-severe-non-helicobacter-gastritis
#8
Geoffrey A Preidis, Ruth Ann Luna, Emily B Hollister, Deborah Schady, Chunxu Gao, Milton J Finegold, James Versalovic, Robert J Shulman
No abstract text is available yet for this article.
September 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27458085/gaba-producing-bifidobacterium-dentium-modulates-visceral-sensitivity-in-the-intestine
#9
K Pokusaeva, C Johnson, B Luk, G Uribe, Y Fu, N Oezguen, R K Matsunami, M Lugo, A Major, Y Mori-Akiyama, E B Hollister, S M Dann, X Z Shi, D A Engler, T Savidge, J Versalovic
BACKGROUND: Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. γ-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal and central pain perception from peripheral afferent neurons. Although gut bacteria are reported to produce GABA, it is not known whether the microbial-derived neurotransmitter modulates abdominal pain...
January 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27420311/development-of-subcortical-pitch-representation-in-three-month-old-chinese-infants
#10
Fuh-Cherng Jeng, Chia-Der Lin, Meng-Shih Chou, Grant R Hollister, John T Sabol, Garrett N Mayhugh, Tang-Chuan Wang, Ching-Yuan Wang
This study investigated the development of subcortical pitch processing, as reflected by the scalp-recorded frequency-following response, during early infancy. Thirteen Chinese infants who were born and raised in Mandarin-speaking households were recruited to partake in this study. Through a prospective-longitudinal study design, infants were tested twice: at 1-3 days after birth and at three months of age. A set of four contrastive Mandarin pitch contours were used to elicit frequency-following responses. Frequency Error and Pitch Strength were derived to represent the accuracy and magnitude of the elicited responses...
February 2016: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/27357660/borrowed-alleles-and-convergence-in-serpentine-adaptation
#11
Brian J Arnold, Brett Lahner, Jeffrey M DaCosta, Caroline M Weisman, Jesse D Hollister, David E Salt, Kirsten Bomblies, Levi Yant
Serpentine barrens represent extreme hazards for plant colonists. These sites are characterized by high porosity leading to drought, lack of essential mineral nutrients, and phytotoxic levels of metals. Nevertheless, nature forged populations adapted to these challenges. Here, we use a population-based evolutionary genomic approach coupled with elemental profiling to assess how autotetraploid Arabidopsis arenosa adapted to a multichallenge serpentine habitat in the Austrian Alps. We first demonstrate that serpentine-adapted plants exhibit dramatically altered elemental accumulation levels in common conditions, and then resequence 24 autotetraploid individuals from three populations to perform a genome scan...
July 19, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27298357/shock-synthesis-of-quasicrystals-with-implications-for-their-origin-in-asteroid-collisions
#12
Paul D Asimow, Chaney Lin, Luca Bindi, Chi Ma, Oliver Tschauner, Lincoln S Hollister, Paul J Steinhardt
We designed a plate impact shock recovery experiment to simulate the starting materials and shock conditions associated with the only known natural quasicrystals, in the Khatyrka meteorite. At the boundaries among CuAl5, (Mg0.75Fe(2+) 0.25)2SiO4 olivine, and the stainless steel chamber walls, the recovered specimen contains numerous micron-scale grains of a quasicrystalline phase displaying face-centered icosahedral symmetry and low phason strain. The compositional range of the icosahedral phase is Al68-73Fe11-16Cu10-12Cr1-4Ni1-2 and extends toward higher Al/(Cu+Fe) and Fe/Cu ratios than those reported for natural icosahedrite or for any previously known synthetic quasicrystal in the Al-Cu-Fe system...
June 28, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27281428/corrigendum-combinatorial-hydrogel-library-enables-identification-of-materials-that-mitigate-the-foreign-body-response-in-primates
#13
Arturo J Vegas, Omid Veiseh, Joshua C Doloff, Minglin Ma, Hok Hei Tam, Kaitlin Bratlie, Jie Li, Andrew R Bader, Erin Langan, Karsten Olejnik, Patrick Fenton, Jeon Woong Kang, Jennifer Hollister-Locke, Matthew A Bochenek, Alan Chiu, Sean Siebert, Katherine Tang, Siddharth Jhunjhunwala, Stephanie Aresta-Dasilva, Nimit Dholakia, Raj Thakrar, Thema Vietti, Michael Chen, Josh Cohen, Karolina Siniakowicz, Meirigeng Qi, James McGarrigle, Stephen Lyle, David M Harlan, Dale L Greiner, Jose Oberholzer, Gordon C Weir, Robert Langer, Daniel G Anderson
No abstract text is available yet for this article.
June 9, 2016: Nature Biotechnology
https://www.readbyqxmd.com/read/27234977/tendon-entrapments-and-dislocations-in-ankle-and-hindfoot-fractures-evaluation-with-multidetector-computed-tomography
#14
David H Ballard, Kevin J Campbell, Lee E Blanton, Jason T Williams, Guillermo Sangster, Anne M Hollister, Alberto A Simoncini
The purpose of this study was to assess the incidence of tendon entrapments and tendon dislocations associated with ankle and hindfoot fractures in patients studied by multidetector computed tomography (MDCT). Additionally, we describe particular tendon injuries associated with specific fractures. This was a retrospective review of all individuals with a trauma-protocol CT for suspected ankle and/or hindfoot fractures during a consecutive 41-month time period at a single Level I Trauma Center. Each patient's images were evaluated by two radiologists and an orthopedic surgeon for tendon entrapment, tendon dislocation, and bone(s) fractured or dislocated...
August 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27218411/dna-methylation-at-stress-related-genes-is-associated-with-exposure-to-early-life-institutionalization
#15
Amy L Non, Brittany M Hollister, Kathryn L Humphreys, Ainash Childebayeva, Kyle Esteves, Charles H Zeanah, Nathan A Fox, Charles A Nelson, Stacy S Drury
OBJECTIVES: Differences in DNA methylation have been associated with early life adversity, suggesting that alterations in methylation function as one pathway through which adverse early environments are biologically embedded. This study examined associations between exposure to institutional care, quantified as the proportion of time in institutional care at specified follow-up assessment ages, and DNA methylation status in two stress-related genes: FKBP5 and SLC6A4. MATERIALS AND METHODS: We analyzed data from the Bucharest Early Intervention Project, which is a prospective study in which children reared in institutional settings were randomly assigned (mean age 22 months) to either newly created foster care or care as usual (to remain in their current placement) and prospectively followed...
September 2016: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/27217061/composition-and-function-of-the-pediatric-colonic-mucosal-microbiome-in-untreated-patients-with-ulcerative-colitis
#16
Rajesh Shah, Julia L Cope, Dorottya Nagy-Szakal, Scot Dowd, James Versalovic, Emily B Hollister, Richard Kellermayer
Inflammatory bowel diseases (IBD) are chronic intestinal inflammatory disorders characterized by a complex disruption of the physiologic interaction between the host immune system and intestinal microbes precipitated by environmental factors. Numerous observations indicate the altered composition and function of the intestinal microbiome of patients with ulcerative colitis (UC), a subtype of IBD. The accuracy of these results may be limited by confounding factors, such as concurrent medication use. To address these limitations, we examined the colonic mucosal microbiome of pediatric patients with UC prior to initiating treatment...
September 2, 2016: Gut Microbes
https://www.readbyqxmd.com/read/27152363/trimeprazine-increases-irs2-in-human-islets-and-promotes-pancreatic-%C3%AE-cell-growth-and-function-in-mice
#17
Alexandra Kuznetsova, Yue Yu, Jennifer Hollister-Lock, Lynn Opare-Addo, Aldo Rozzo, Marianna Sadagurski, Lisa Norquay, Jessica E Reed, Ilham El Khattabi, Susan Bonner-Weir, Gordon C Weir, Arun Sharma, Morris F White
The capacity of pancreatic β cells to maintain glucose homeostasis during chronic physiologic and immunologic stress is important for cellular and metabolic homeostasis. Insulin receptor substrate 2 (IRS2) is a regulated adapter protein that links the insulin and IGF1 receptors to downstream signaling cascades. Since strategies to maintain or increase IRS2 expression can promote β cell growth, function, and survival, we conducted a screen to find small molecules that can increase IRS2 mRNA in isolated human pancreatic islets...
2016: JCI Insight
https://www.readbyqxmd.com/read/27127617/associations-between-chlorophyll-a-and-various-microcystin-lr%C3%A2-health-advisory-concentrations
#18
Jeffrey W Hollister, Betty J Kreakie
Cyanobacteria harmful algal blooms (cHABs) are associated with a wide range of adverse health effects that stem mostly from the presence of cyanotoxins. To help protect against these impacts, several health advisory levels have been set for some toxins. In particular, one of the more common toxins, microcystin-LR, has several advisory levels set for drinking water and recreational use. However, compared to other water quality measures, field measurements of microcystin-LR are not commonly available due to cost and advanced understanding required to interpret results...
2016: F1000Research
https://www.readbyqxmd.com/read/27104930/evaluation-of-multi-scale-mineralized-collagen-polycaprolactone-composites-for-bone-tissue-engineering
#19
D W Weisgerber, K Erning, C L Flanagan, S J Hollister, B A C Harley
A particular challenge in biomaterial development for treating orthopedic injuries stems from the need to balance bioactive design criteria with the mechanical and geometric constraints governed by the physiological wound environment. Such trade-offs are of particular importance in large craniofacial bone defects which arise from both acute trauma and chronic conditions. Ongoing efforts in our laboratory have demonstrated a mineralized collagen biomaterial that can promote human mesenchymal stem cell osteogenesis in the absence of osteogenic media but that possesses suboptimal mechanical properties in regards to use in loaded wound sites...
August 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27080737/psyllium-fiber-reduces-abdominal-pain-in-children-with-irritable-bowel-syndrome-in-a-randomized-double-blind-trial
#20
Robert J Shulman, Emily B Hollister, Kevin Cain, Danita I Czyzewski, Mariella M Self, Erica M Weidler, Sridevi Devaraj, Ruth Ann Luna, James Versalovic, Margaret Heitkemper
BACKGROUND & AIMS: We sought to determine the efficacy of psyllium fiber treatment on abdominal pain and stool patterns in children with irritable bowel syndrome (IBS). We evaluated effects on breath hydrogen and methane production, gut permeability, and microbiome composition. We also investigated whether psychological characteristics of children or parents affected the response to treatment. METHODS: We performed a randomized, double-blind trial of 103 children (mean age, 13 ± 3 y) with IBS seen at primary or tertiary care settings...
April 11, 2016: Clinical Gastroenterology and Hepatology
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