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Atorvastatin fistula

Laisel Martinez, Juan C Duque, Luis A Escobar, Marwan Tabbara, Arif Asif, Fadi Fayad, Roberto I Vazquez-Padron, Loay H Salman
PURPOSE: Whether statins improve arteriovenous fistula (AVF) outcomes is still a matter of debate. Taking into consideration the existing physicochemical differences between individual drugs, this study evaluates the impact of three different statins (atorvastatin, rosuvastatin and simvastatin) on one-stage and two-stage AVF outcomes. METHODS: Using a retrospective cohort of 535 patients, we analyzed the effects of each statin on primary failure and primary patency using multivariate logistic regressions and Cox proportional hazard models...
October 15, 2016: Journal of Vascular Access
Rizwana Abid, Riaz Mahmood, Hulikal Shivashankara Santosh Kumar
CONTEXT: The plant Cassia fistula L. (Caesalpiniaceae) fruit was widely used by traditional practitioners to treat cardiovascular diseases (CVDs) in India. Hyperlipidemia is a lipid metabolism disorder and the major risk factor for the development of CVDs. Although most of the current hypolipidemic drugs are expensive and have potential side effects, the research focusing on natural alternative medicines is relevant. OBJECTIVE: To investigate the hypolipidemic and antioxidant effects of ethanol extract of C...
June 3, 2016: Pharmaceutical Biology
Gang Cheng, Geng Xu, Hong-wen Cai, Hui-hua Wang, Xiao-feng Bao
AIM: To examine the role of atorvastatin on volume-overload-induced heart failure and to test the hypothesis that atorvastatin inhibits MMP-2 and 9 expression in heart failure with non-ischemic etiology. METHODS: Arteriovenous (AV) fistula-treated rats were administered with atorvastatin (3 mg/kg/d) or vehicle for 17 weeks. Ventricular hypertrophy and heart failure were assessed by echocardiography, B-type natriuretic peptide BNP mRNA level and morphological measurement...
April 2007: Acta Pharmacologica Sinica
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