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https://www.readbyqxmd.com/read/28449481/procalcitonin-as-preoperative-marker-for-surgery-in-advanced-parapneumonic-empyema
#1
Claudio Caviezel, Philipp Schuetz, Stephan Gerdes, Franco Gambazzi
BACKGROUND: The optimal time point for surgical management of advanced parapneumonic empyema in need of open pleurectomy and decortication remains unclear. We hypothesized that surgical outcomes will be better when procalcitonin (PCT) levels have dropped to normal ranges as evidence for resolution of the underlying pneumonia. METHODS: We retrospectively analyzed outcomes of 38 patients with advanced parapneumonic empyema who underwent open decortication and pleurectomy with available preoperative PCT (pPCT) values...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449050/cardioscape-mapping-the-cardiovascular-funding-landscape-in-europe
#2
Axel Radlach Pries, Anastasia Naoum, Helmut Habazettl, Mathias Dunkel, Robert Preissner, Caroline J Coats, Ana Tornada, Francesco Orso, Frans Van de Werf, David A Wood
Aims: The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transformed into an on-line and up-to-date resource of great relevance for researchers, funding bodies and policymakers and could be a role model for mapping CV research funding in Europe and beyond...
April 25, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28448862/the-first-case-report-of-failed-single-anastomosis-duodeno-ileal-bypass-converted-to-one-anastomosis-gastric-bypass-mini-gastric-bypass
#3
Sonja Chiappetta, Christine Stier, Oliver Scheffel, Sophia Theodoridou, Rudolf Weiner
INTRODUCTION: The established single-anastomosis-duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is based on a sleeve gastrectomy (SG) as the restrictive part of the procedure. Due to preserved pylorus, SG has the disadvantage of a high-pressure system with de novo or worsening of existing gastroesophageal reflux disease (GERD). CASE PRESENTATION: A female patient presented herself due to protracted GERD and weight regain after multiple bariatric surgeries...
April 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28448394/in-response
#4
Sam Baete, Gerd Vercruysse, Margot Vander Laenen, Pieter De Vooght, Dimitri Dylst, Jeroen van Melkebeek, Maud Beran, Jan Van Zundert, René Heylen, Willem Boer, Sam Van Boxstael, Tom Fret, Hans Verhelst, Cathy De Deyne, Frank Jans, Pascal Vanelderen
No abstract text is available yet for this article.
April 24, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28446998/pathology-of-esophageal-cancer-and-barrett-s-esophagus
#5
REVIEW
Shilpa Jain, Sadhna Dhingra
Esophageal cancer is a serious malignancy with high mortality. The two common distinctive pathologic subtypes of esophageal cancer are squamous cell carcinoma and adenocarcinoma. These differ with regards to etiology, ethnic distribution, pathogenesis, and location in the esophagus. The precursor lesions are also unique to each subtype. Squamous cell carcinoma is more common in East Asia, is linked to smoking and tobacco use, more commonly involves the middle esophagus, and the precursor lesion is squamous dysplasia...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28446997/endoscopic-submucosal-dissection-and-endoscopic-mucosal-resection-for-early-stage-esophageal-cancer
#6
REVIEW
Bo Ning, Mohamed M Abdelfatah, Mohamed O Othman
Mortality from esophageal cancer remains high despite advances in medical therapy. Although the incidence of squamous cell carcinoma of the esophagus remains unchanged, the incidence of the esophageal adenocarcinoma has increased over time. Gastroesophageal reflux disease (GERD and obesity are contributing factors to the development of Barrett's esophagus and subsequent development of adenocarcinoma. Early recognition of the disease can lead to resection of esophageal cancer prior to the development of lymphovascular invasion...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28446996/barrett-s-esophagus-best-practices-for-treatment-and-post-treatment-surveillance
#7
REVIEW
Nabil M Mansour, Hashem B El-Serag, Sharmila Anandasabapathy
Barrett's esophagus (BE) is a premalignant condition that increases the risk of esophageal adenocarcinoma (EAC). Significantly more common in the Western world, risk factors include increased age, male sex, white race, gastro-esophageal reflux disease (GERD), central obesity, and cigarette smoking. The rates of progression to cancer depend on the grade of Barrett's dysplasia. Screening for BE is recommended in patients with GERD and additional risk factors. Endoscopic surveillance of patients with BE likely improves overall outcomes...
March 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28446978/optimizing-the-diagnosis-and-therapy-of-barrett-s-esophagus
#8
REVIEW
Juan A Muñoz-Largacha, Hiran C Fernando, Virginia R Litle
The incidence of Barrett's esophagus (BE) in the Western world has increased over the last decades. BE is considered a premalignant lesion that can progress to esophageal adenocarcinoma (EAC), a highly aggressive malignancy with poor survival rates. The close association between BE and EAC highlights the need for an early diagnosis in order to improve survival and outcomes in this group of patients. Although the evidence for BE screening with conventional endoscopy is controversial and limited by cost-effectiveness studies, screening can be suggested in patients with chronic gastroesophageal reflux disease (GERD) and two or more risk factors for EAC...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28446882/modified-low-dose-triiodo-l-thyronine-therapy-safely-improves-function-following-myocardial-ischemia-reperfusion-injury
#9
Viswanathan Rajagopalan, Youhua Zhang, Christine Pol, Clifford Costello, Samantha Seitter, Ann Lehto, Olga V Savinova, Yue-Feng Chen, A Martin Gerdes
Background: We have shown that thyroid hormones (THs) are cardioprotective and can be potentially used as safe therapeutic agents for diabetic cardiomyopathy and permanent infarction. However, no reliable, clinically translatable protocol exists for TH treatment of myocardial ischemia-reperfusion (IR) injury. We hypothesized that modified low-dose triiodo-L-thyronine (T3) therapy would confer safe therapeutic benefits against IR injury. Methods: Adult female rats underwent left coronary artery ligation for 60 min or sham surgeries...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28445907/-acceptance-of-emotion-sensitive-training-systems-of-individuals-suffering-from-facial-paralysis-and-their-relatives
#10
Uwe Altmann, Susanne Worrack, Magdalena C Kaczmarek, Julia Mühleck, Gerd Fabian Volk, Orlando Guntinas-Lichius, Bernhard M Strauß
No abstract text is available yet for this article.
April 26, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28445810/circulating-cadmium-concentration-and-risk-of-aortic-aneurysms-a-nested-case-control-study-within-the-malm%C3%A3-diet-and-cancer-cohort
#11
Björn Fagerberg, Yan Borné, Gerd Sallsten, J Gustav Smith, Stefan Acosta, Margaretha Persson, Olle Melander, Niklas Forsgard, Anders Gottsäter, Bo Hedblad, Lars Barregard, Gunnar Engström
BACKGROUND AND AIMS: Diet and smoking expose the general population to cadmium (Cd), which is a toxic metal that accumulates in the arterial wall. In experimental studies, Cd causes reductions in proliferation of smooth muscle cells and cellular synthesis of procollagen. The aim of this study was to examine whether blood Cd levels, a valid measure of Cd exposure, are associated with increased risk of abdominal aortic aneurysm (AAA). METHODS: All middle-aged men and women enrolled in the Malmö Diet and Cancer study (n = 30 447) were followed from the baseline examination in 1991-1996 through 2009...
April 8, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28445106/tension-free-inlay-repair-of-large-hiatal-hernias-using-dual-sided-composite-ptfe-eptfe-meshes-in-laparoscopic-surgery-for-gastroesophageal-reflux-disease
#12
Alexander M Prusa, Ivan Kristo, Erwin Rieder, Claudia Ringhofer, Reza Asari, Johannes Miholic, Sebastian F Schoppmann
BACKGROUND: Patients with gastroesophageal reflux disease (GERD) also frequently suffer from concomitant hiatal hernia. It has been described that a preoperative hiatal hernia of ≥3 cm is associated with a more than threefold relative risk for reflux symptom recurrence after fundoplication without mesh reinforcement. In this report, we describe our experience with the implantation of dual-sided composite PTFE/ePTFE meshes in a tension-free fashion during laparoscopic antireflux surgery (LARS)...
April 26, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28444229/a-novel-but-frequent-variant-in-lpa-kiv-2-is-associated-with-a-pronounced-lp-a-and-cardiovascular-risk-reduction
#13
Stefan Coassin, Gertraud Erhart, Hansi Weissensteiner, Mariana Eca Guimarães de Araújo, Claudia Lamina, Sebastian Schönherr, Lukas Forer, Margot Haun, Jamie Lee Losso, Anna Köttgen, Konrad Schmidt, Gerd Utermann, Annette Peters, Christian Gieger, Konstantin Strauch, Armin Finkenstedt, Reto Bale, Heinz Zoller, Bernhard Paulweber, Kai-Uwe Eckardt, Alexander Hüttenhofer, Lukas A Huber, Florian Kronenberg
Aims: Lp(a) concentrations represent a major cardiovascular risk factor and are almost entirely controlled by one single locus (LPA). However, many genetic factors in LPA governing the enormous variance of Lp(a) levels are still unknown. Since up to 70% of the LPA coding sequence are located in a difficult to access hypervariable copy number variation named KIV-2, we hypothesized that it may contain novel functional variants with pronounced effects on Lp(a) concentrations. We performed a large scale mutation analysis in the KIV-2 using an extreme phenotype approach...
April 25, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28443343/impact-on-diabetes-self-management-and-glycemic-control-of-a-new-color-based-smbg-meter
#14
Oliver Schnell, Gerd Klausmann, Bettina Gutschek, Rosa Maria Garcia-Verdugo, Michael Hummel
BACKGROUND: Self-monitoring of blood glucose (SMBG) is a key pillar of personal diabetes management. The objective of this observational study was to analyze diabetes self-management (DSM) and glycemic outcomes before and during system implementation in real-life settings of a blood glucose meter system with a color-coded display of glucose levels, which helps identify out-of-range levels. METHODS: A total of 193 insulin-treated diabetes patients (11% T1DM; 55% male, age 60 ± 4 years, mean diabetes duration 14 ± 9 years, HbA1c 8...
April 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28443162/novel-measurement-technique-for-the-sagittal-vertical-axis-and-its-clinical-application-in-adult-spinal-deformity
#15
Go Yoshida, Kenta Kurosu, Yu Yamato, Tomohiko Hasegawa, Tatsuya Yasuda, Daisuke Togawa, Yukihiro Matsuyama
STUDY DESIGN: Prospective physical measurement of the sagittal vertical axis (SVA). PURPOSE: To evaluate a simple method for measuring SVA by analyzing its relationship with radiographic measurements and clinical appearance. OVERVIEW OF LITERATURE: No studies have examined physical measurements using the cranial center of gravity (CCG) in a relaxed standing position. METHODS: The physical measurement of the horizontal distance between CCG and spina iliaca posterior superior (CCG-SIPS) was measured using a straight ruler in 252 healthy volunteers and 56 patients with adult spinal deformity...
April 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28442775/deterministic-bragg-coherent-diffraction-imaging
#16
Konstantin M Pavlov, Vasily I Punegov, Kaye S Morgan, Gerd Schmalz, David M Paganin
A deterministic variant of Bragg Coherent Diffraction Imaging is introduced in its kinematical approximation, for X-ray scattering from an imperfect crystal whose imperfections span no more than half of the volume of the crystal. This approach provides a unique analytical reconstruction of the object's structure factor and displacement fields from the 3D diffracted intensity distribution centred around any particular reciprocal lattice vector. The simple closed-form reconstruction algorithm, which requires only one multiplication and one Fourier transformation, is not restricted by assumptions of smallness of the displacement field...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28441441/a-novel-multiplexed-probe-based-quantitative-pcr-assay-for-the-soybean-root-and-stem-rot-pathogen-phytophthora-sojae-utilizes-its-transposable-element
#17
James S Haudenshield, Jeong Y Song, Glen L Hartman
Phytophthora root rot of soybean [Glycine max (L.) Merr.] is caused by the oomycete Phytophthora sojae (Kaufm. & Gerd.). P. sojae has a narrow host range, consisting primarily of soybean, and it is a serious pathogen worldwide. It exists in root and stem tissues as mycelium, wherein it can form oospores which subsequently germinate to release motile, infectious zoospores. Molecular assays detecting DNA of P. sojae are useful in disease diagnostics, and for determining the presence of the organism in host tissues, soils, and runoff or ponded water from potentially infested fields...
2017: PloS One
https://www.readbyqxmd.com/read/28439814/imaging-the-accumulated-intracellular-microalgal-lipids-as-a-response-to-temperature-stress
#18
Khaled N M Elsayed, Tatiana A Kolesnikova, Anja Noke, Gerd Klöck
Over the last few decades, many scientists considered microalgae as promising actors for future biofuels because of the high lipid productivity inside their cells. Moreover, much attention has been paid to algal lipids as they can be used in biodiesel production. In this study, we optimized the different suitable conditions such as incubation time, incubation temperature, Dimethylesulfoxide and Nile red concentrations of the lipophilic fluorescence dye Nile red as an excellent and fast vital stain to detect and quantify intracellular lipids...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28439593/reversible-restructuring-of-supported-au-nanoparticles-during-butadiene-hydrogenation-revealed-by-operando-gisaxs-giwaxs
#19
David James Martin, Donato Decarolis, Yaroslav I Odarchenko, Jennifer J Herbert, Thomas Arnold, Jonathan Rawle, Chris Nicklin, Hans-Gerd Boyen, Andrew M Beale
Periodically arranged, monodisperse gold nanoparticles supported on flat silicon substrates were studied for the hydrogenation of 1,3-butadiene under operando conditions using Grazing Incidence Small- and Wide-Angle X-ray Scattering (GISAXS/GIWAXS). It was found that the composition and shape of the nanoparticles depends very much on the chemical environment; the particles are shown to be dynamic, undergoing reversible size and shape change particularly during catalytic reaction, highlighting a dynamism often not observed in traditional studies...
April 25, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28437356/scoliosis-is-a-risk-factor-for-gastroesophageal-reflux-disease-in-adult-spinal-deformity
#20
Naobumi Hosogane, Kota Watanabe, Mitsuru Yagi, Shinjiro Kaneko, Yoshiaki Toyama, Morio Matsumoto
STUDY DESIGN: A prospective observational study. OBJECTIVE: To evaluate whether scoliosis is a risk factor for gastroesophageal reflux disease (GERD) in elderly patients. SUMMARY OF BACKGROUND DATA: Sagittal spinal deformities are reported to cause GERD, but its association with spinal deformity in the coronal plane is not well studied. METHODS: We examined 190 patients with spinal disorders (mean age 70.6±8.6 y) who underwent standing whole-spine x-rays in the coronal and sagittal planes...
May 2017: Clinical Spine Surgery
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