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Applied behavior analysys, behavior analysys

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https://www.readbyqxmd.com/read/29666832/structure-and-function-analysis-in-circulating-tumor-cells-using-nanotechnology-to-study-nuclear-size-in-prostate-cancer
#1
REVIEW
Nu Yao, Yu-Jen Jan, Shirley Cheng, Jie-Fu Chen, Leland Wk Chung, Hsian-Rong Tseng, Edwin M Posadas
Professor Donald Coffey and his laboratory pioneered studies showing the relationships between nuclear shape and cellular function. In doing so, he and his students established the field of nuclear morphometry in prostate cancer. By using perioperative tissues via biopsies and surgical sampling, Dr. Coffey's team discovered that nuclear shape and other pathologic features correlated with clinical outcome measures. Cancer cells also exist outside of solid tumor masses as they can be shed from both primary and metastatic lesions into the circulatory system...
2018: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/29666285/type-ii-secretion-dependent-aminopeptidase-lapa-and-acyltransferase-plac-are-redundant-for-nutrient-acquisition-during-legionella-pneumophila-intracellular-infection-of-amoebas
#2
Richard C White, Felizza F Gunderson, Jessica Y Tyson, Katherine H Richardson, Theo J Portlock, James A Garnett, Nicholas P Cianciotto
Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii , although these genes had been considered dispensable on the basis of the behavior of mutants lacking either lapA and lapB or plaC A plaC mutant showed even higher levels of lapA and lapB transcripts, and a lapA lapB mutant showed heightening of plaC mRNA levels, suggesting that the role of the LapA/B aminopeptidase is compensatory with respect to that of the PlaC acyltransferase...
April 17, 2018: MBio
https://www.readbyqxmd.com/read/29665018/differential-response-of-human-dermal-fibroblast-subpopulations-to-visible-and-near-infrared-light-potential-of-photobiomodulation-for-addressing-cutaneous-conditions
#3
Charles Mignon, Natallia E Uzunbajakava, Irene Castellano-Pellicena, Natalia V Botchkareva, Desmond J Tobin
BACKGROUND OBJECTIVES: The past decade has witnessed a rapid expansion of photobiomodulation (PBM), demonstrating encouraging results for the treatment of cutaneous disorders. Confidence in this approach, however, is impaired not only by a lack of understanding of the light-triggered molecular cascades but also by the significant inconsistency in published experimental outcomes, design of the studies and applied optical parameters. This study aimed at characterizing the response of human dermal fibroblast subpopulations to visible and near-infrared (NIR) light in an attempt to identify the optical treatment parameters with high potential to address deficits in aging skin and non-healing chronic wounds...
April 17, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29664666/adherence-to-principles-of-medical-ethics-among-physicians-in-mazandaran-province-iran
#4
Ahmad Ghaderi, Farhad Malek, Mohammad Mohammadi, Somayeh Rostami Maskopaii, Amir Hamta, Seyyed Abdollah Madani
BACKGROUND: Considering that medical ethics is an applied subject providing systematic solutions to help physicians with moral issues, this research aimed to evaluate adherence to the principles of medical ethics among physicians on the basis of attitude of physicians of Mazandaran province. METHODS: This cross-sectional study was conducted in Mazandaran province, Iran during 2015. A researcher-made questionnaire was used for data collection. The questionnaire was first completed by 40 physicians and its reliability was confirmed by obtaining a Cronbach's alpha coefficient equal to 0...
January 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29662259/psychometric-validation-of-the-columbia-suicide-severity-rating-scale-in-spanish-speaking-adolescents
#5
Daniel Serrani Azcurra
Introduction: Adolescent suicide is a major public health issue, and early and accurate detection is of great concern. There are many reliable instruments for this purpose, such as the Columbia-Suicide severity rating scale (C-SSRS), but no validation exists for Spanish speaking Latin American adolescents. Objetive: To assess psychometric properties and cut-off scores of the C-SSRS in Spanish speaking adolescents. Methods: Exploratory assessment with principal component analysis (PCA) and Varimax rotation, and confirmatory analysis (CFA) were performed on two groups with 782 and 834 participants respectively (N=1616)...
December 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29661241/breaking-bad-habits-by-improving-executive-function-in-individuals-with-obesity
#6
Vanessa Allom, Barbara Mullan, Evelyn Smith, Phillipa Hay, Jayanthi Raman
BACKGROUND: Two primary factors that contribute to obesity are unhealthy eating and sedentary behavior. These behaviors are particularly difficult to change in the long-term because they are often enacted habitually. Cognitive Remediation Therapy has been modified and applied to the treatment of obesity (CRT-O) with preliminary results of a randomized controlled trial demonstrating significant weight loss and improvements in executive function. The objective of this study was to conduct a secondary data analysis of the CRT-O trial to evaluate whether CRT-O reduces unhealthy habits that contribute to obesity via improvements in executive function...
April 16, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29656157/simultaneous-enantiomeric-analysis-of-eight-pesticides-in-soils-and-river-sediments-by-chiral-liquid-chromatography-tandem-mass-spectrometry
#7
Pengfei Zhao, Jing Zhao, Shuo Lei, Xingjie Guo, Longshan Zhao
A rapid and sensitive multi-residue method was developed for the simultaneous quantification of eight chiral pesticides (including diniconazole, metalaxyl, paclobutrazol, epoxiconazole, myclobutanil, hexaconazole, napropamide and isocarbophos) at enantiomeric levels in environmental soils and sediments using chiral liquid chromatography-tandem mass spectrometry based on a combined pretreatment of matrix solid-phase dispersion and dispersive liquid-liquid microextraction (MSPD-DLLME). Under optimized conditions, 0...
April 3, 2018: Chemosphere
https://www.readbyqxmd.com/read/29655685/polygonum-aviculare-l-extract-reduces-fatigue-by-inhibiting-neuroinflammation-in-restraint-stressed-mice
#8
Sun Haeng Park, Seol Jang, Eunjung Son, Si Woo Lee, Sun Dong Park, Yoon-Young Sung, Ho Kyoung Kim
BACKGROUND: Chronic fatigue patients experience various neuropsychological symptoms, including fatigue behaviors, chronic pain, and depression. They also display immune system dysregulation. Polygonum aviculare L. extract (PAE) is a traditional herbal medicine used to treat inflammatory diseases by reportedly decreasing pro-inflammatory cytokine production. HYPOTHESIS/PURPOSE: We hypothesized that the anti-inflammatory properties of PAE would attenuate fatigue symptoms in a mouse model of restraint stress...
March 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29650320/assessment-of-auditory-threshold-using-multiple-magnitude-squared-coherence-and-amplitude-modulated-tones-monaural-stimulation-around-40-hz
#9
Glaucia de Morais Silva, Felipe Antunes, Catherine Salvador Henrique, Leonardo Bonato Felix
BACKGROUND AND OBJECTIVE: The use of objective detection techniques applied to the auditory steady-state responses (ASSRs) for the assessment of auditory thresholds has been investigated over the years. The idea consists in setting up the audiometric profile without subjective inference from patients and evaluators. The challenge encountered is to reduce the detection time of auditory thresholds reaching high correlation coefficients between the objective and the conventional thresholds, as well as reducing difference between thresholds...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29650206/correlation-between-parent-adolescent-communication-and-adolescents-premarital-sex-risk
#10
Widyatuti, Citra Hafilah Shabrina, Astuti Yuni Nursasi
OBJECTIVE: Previous studies have indicated the parent-adolescent relationship has a correlation to adolescents' premarital sex behavior risk. Therefore, the aim of this study was to discover the influence of parent-adolescent communication on adolescents' risk of sexual issues. METHOD: This was a quantitative study with a cross-sectional design. The population of this study consisted of students from a high school in Jakarta. A purposive sampling technique was used, which resulted in the selection of 253 students as samples...
February 2018: Enfermería Clínica
https://www.readbyqxmd.com/read/29649903/pharmacokinetic-evaluation-of-quetiapine-fumarate-controlled-release-hybrid-hydrogel-a-healthier-treatment-of-schizophrenia
#11
Muhammad Akhlaq, Faiza Maryam, Abdelhamid Elaissari, Hashmat Ullah, Muhammad Adeel, Abid Hussain, Muhammad Ramzan, Obaid Ullah, Muhammad Zeeshan Danish, Shehla Iftikhar, Nighat Aziz
The current study aimed to rationally develop and characterize pH-sensitive controlled release hydrogels by graft polymerization of gelatin (Gel) and hydroxypropyl methyl cellulose (HPMC) in the presence of glutaraldehyde (GA) using quetiapine fumarate for the treatment of schizophrenia. The prepared hydrogels discs were subjected to various physicochemical studies including: swelling, diffusion, porosity, sol-gel analysis, Fourier transform infrared spectroscopy, differential scanning calorimetry, and scanning electron microscopy...
November 2018: Drug Delivery
https://www.readbyqxmd.com/read/29648901/training-health-professions-preceptors-in-rural-practices-a-challenge-for-interprofessional-practice-and-education
#12
Molly L Osborne, Virginia P Tilden, Elizabeth Eckstrom
The ever-increasing mandate for interprofessional practice and education (IPE) faces challenges in rural settings. Oregon Health & Science University (OHSU) launched a preceptor development program as part of its commitment to training interprofessional student groups in rural settings. The objectives of the program were to (1) encourage preceptors to exemplify team behaviors; (2) characterize contemporary learners and learning styles of trainees; (3) encourage interprofessional precepting skills, and (4) apply practical teaching tools in the clinical setting...
April 12, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29644992/the-lived-experience-of-parents-whose-children-discharged-to-home-after-cardiac-surgery-for-congenital-heart-disease
#13
Silvio Simeone, Nicol Platone, Marco Perrone, Valentina Marras, Gianluca Pucciarelli, Martina Benedetti, Grazia Dell'Angelo, Teresa Rea, Assunta Guillari, Paola Da Valle, Gianpaolo Gargiulo, Stefano Botti, Giovanna Artioli, Giuseppe Comentale, Salvatore Ferrigno, Gaetano Palma, Stefania Baratta
BACKGROUND: Congenital Heart Diseases (CHDs) afflicting children are estimated in 8 per 1000 live births. Recent advances in surgery and medical treatments allowed an improvement in survival rates leading to changes in diseases management as chronic conditions. Parents involvement during clinical pathways is considered an essential component of care, but frequently they experience stress and anxiety conditions during the care path. These feelings are typical of the pre and peri-operative period, however they don't disappear easily and sometimes they can increase after hospital discharge, affecting the family environment and its behaviors...
April 4, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29643766/spatiotemporal-control-of-gpr37-signaling-and-its-behavioral-effects-by-optogenetics
#14
Wu Zheng, Jianhong Zhou, Yanan Luan, Jianglan Yang, Yuanyuan Ge, Muran Wang, Beibei Wu, Zhongnan Wu, Xingjun Chen, Fei Li, Zhihui Li, Sergii Vakal, Wei Guo, Jiang-Fan Chen
Despite the progress in deorphanization of G Protein-Coupled Receptors (GPCRs), ≈100 GPCRs are still classified as orphan receptors without identified endogenous ligands and with unknown physiological functions. The lack of endogenous ligands triggering GPCR signaling has hampered the study of orphan GPCR functions. Using GPR37 as an example, we provide here the first demonstration of the channelrhodopsin 2 (ChR2)-GPCR approach to bypass the endogenous ligand and selectively activate the orphan GPCR signal by optogenetics...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29629455/lanthanide-atom-substitutionally-doped-blue-phosphorene-electronic-and-magnetic-behaviors
#15
Bo Su, Nan Li
The structure, energy, electronic and magnetic properties of lanthanide (La, Ce, Pr, Nd, Pm, Eu and Gd) doped blue phosphorene are systematically investigated by using the GGA+U method. The calculated results show that the semi-metallic or dilute magnetic semiconductor characteristics can be achieved by substitutional doping of lanthanide atoms in blue phosphorene. From La- to Gd-doped blue phosphorene, the calculated spin magnetic moments are respectively 0.0, 1.0, 2.0, 3.0, 4.0, 8.0 and 7.0 μB, which are generally proportional to the number of the spin-parallel 4f electrons in dopants...
April 9, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29629053/effective-factors-on-menstrual-health-among-female-students-in-bam-city-a-qualitative-study
#16
Mohammad Ali Morowatisharifabad, Aliakbar Vaezi, Neda Mohammadinia
Background: Menarche is an independent puberty event in a girl's life, and is associated with physical growth, ability in marriage and fertility. Therefore, poor menstrual health can be a major determinant of morbidity, as well as physical, mental and social problems in this age group. Objective: The aim of this study was to explore the effective factors on menstrual health among female students in Bam city. Methods: The qualitative study was conducted using content analysis approach in 2017...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29628735/chilean-dentistry-students-levels-of-empathy-and-empathic-erosion-necessary-evaluation-before-a-planned-intervention-levels-of-empathy-evaluation-and-intervention
#17
Víctor Patricio Díaz-Narváez, Ana Cristina Amezaga-Avitia, Pablo Alexander Sarabia-Alvarez, Macarena Lagos-Elgueta, Monserrat Saavedra-Madrid, Pablo Silva-Reyes, Mariela Padilla, María Paz Rodríguez-Hopp
Objectives: To estimate the general empathy levels and the potential for empathic growth in Dentistry students and demonstrate that the empathic erosion model is not med. Material and methods: Exploratory and cross-sectional study. Population: First- to fifth-year Dentistry students at Universidad San Sebastián, Santiago Campus (Chile). The total student population (N) was 800. The participants completed the Jefferson Scale of Empathy in its Spanish version for medical students, validated and adapted in Chile...
April 2018: Saudi Dental Journal
https://www.readbyqxmd.com/read/29628179/modeling-and-real-time-simulation-of-an-hvdc-inverter-feeding-a-weak-ac-system-based-on-commutation-failure-study
#18
Mohamed Mankour, Mounir Khiat, Leila Ghomri, Abdelkader Chaker, Mourad Bessalah
This paper presents modeling and study of 12-pulse HVDC (High Voltage Direct Current) based on real time simulation where the HVDC inverter is connected to a weak AC system. In goal to study the dynamic performance of the HVDC link, two serious kind of disturbance are applied at HVDC converters where the first one is the single phase to ground AC fault and the second one is the DC link to ground fault. The study is based on two different mode of analysis, which the first is to test the performance of the DC control and the second is focalized to study the effect of the protection function on the system behavior...
April 5, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29625329/multiporous-molybdenum-carbide-nanosphere-as-a-new-charming-electrode-material-for-highly-sensitive-simultaneous-detection-of-guanine-and-adenine
#19
Lei Zhang, Jing Zhang
By introduction of Mo metal species (molybdenum-based polyoxometalates) into the Cu-MOF as co-precursor, molybdenum carbide nanosphere (Mox C@C) was prepared via a simple calcining routine and a further etching the metallic Cu process. The obtained Mox C@C showed a unique structure where well-dispersed Mox C nanoparticles (NPs) were encapsulated in porous carbon matrix. As-fabricated novel 3D porous architecture Mox C@C nanosphere exhibited a potent and persistent electro-oxidation behavior followed by well-separated oxidation peaks (peak to peak voltage is about 350 mV) toward adenine (A) and guanine (G) by differential pulse voltammetry (DPV)...
March 29, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29625156/a-schizophrenia-like-behavioral-trait-in-the-shr-model-applying-confirmatory-factor-analysis-as-a-new-statistical-tool
#20
Fernanda Fiel Peres, Raí Álvares Eufrásio, Douglas Albuquerque Gouvêa, Mariana Cepollaro Diana, Camila Maurício Santos, Walter Swardfager, Vanessa Costhek Abílio, Hugo Cogo-Moreira
Questionnaires that assess symptoms of schizophrenia patients undergo strict statistical validation, often using confirmatory factor analysis (CFA). CFA allows testing the existence of a trait that both collectively explains the symptoms and gathers the information in a single general index. In rodents, some behaviors are used to model psychiatric symptoms, but no single test or paradigm adequately captures the disorder's phenotype in toto. This work investigated the existence of a behavioral trait in the SHR strain underlying five behavioral tasks used in schizophrenia animal studies and altered in this strain: locomotor activity, rearing behavior, social interaction, prepulse inhibition of startle and contextual fear conditioning...
April 3, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
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